HOW OUR

PHAGES
W H AT A R E
PHAGES?
Bacteriophages, or just phages, are
microorganisms that exclusively destroy
specific bacteria, they are their natural enemy.
When they recognize one of them, the phages
WORK enter the bacteria's system and use their
cellular machinery to replicate and destroy it.

PHAGELAB
E L I M I N AT I O N
C O C K TA I L OF THE
We use a cocktail of BACTERIUM
specialized phages against
highly pathogenic bacteria. Bacteriophages can carry out a
lytic cycle, where they cause lysis
or elimination of the bacterium.

F U N DA M E N TA L
CRITERIA

All PhageLab bacteriophages must meet 3

HEAD
fundamental criteria:

DNA

A . LY T I C B. SECURITY C. SCALABILITY
EFFICACY PROTEIN

PHAGES
We guarantee efficient results by testing
MINEFIELD
a cocktail against selected bacteria,
where our large-scale production system When the bacteriophages that
S C H E M AT I C D I AG R A M O F
allows us to address challenges of BACTERIOPHAGE T4
make up PhageLab products
industrial volumes. reach the intestine, they adhere to
the intestinal mucus creating a
TA I L "minefield" against the bacteria
that have colonized or will
LO N G TA I L colonize this organ.
FIBERS

We can completely eliminate and

B A S E P L AT E control diseases like E. coli and
Salmonella in poultry, calves
and cattle.

T H E LY TIC CYC L E

A . HOST B. ADSORPTION & C . R E P L I CAT I O N D. PHAGE E . E N D O LY S I S F . LY S I S

RECOGNITION DNA INJECTION STAG E A S S E M B LY EXPRESION STAG E

SCIENCE WORKS, AND WE CAN PROVE IT.

www.phage-lab.com
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HOW OUR All PhageLab

PHAGES
bacteriophages
must meet 3
fundamental
criteria:
WORK
I N D E TA I L A. LYTIC EFFICACY

1
In vitro experiments show that bacteriophages have
a specific spectrum of action against target bacteria.
W H AT A R E Testing the bacteriophage cocktail against local bacteria increases
PHAGES? the probability of success of the phage treatment in the field.
Bacteriophages (phages for
short) are viruses capable of B. SECURITY
invading only specific bacteria.
Bacteriophages must have a lytic cycle
Its structure is composed of a unit of and must not have lysogenic genes (such
genetic material and different protein structures. as integrases or recombination sites) that
They are abundantly present in the biosphere and are known can generate their integration into the
to be the natural antagonists of bacteria, since in order to genome of the target bacterium and not eliminate it. At the
"survive" they need to specifically recognize one of them, same time, they must not have other risk genes, such as

2
enter its system and use its cellular machinery to produce virulence factors or resistance to antibiotics. Therefore, the
copies of themselves. formulation is 100% lytic and safe for the host.

C. SCALABILITY
E L I M I N AT I O N
OF THE PhageLab has a large-scale bacteriophage
BACTERIUM production system with unique volume and

5
concentration yields in the world. All
Bacteriophages can bacteriophages in PhageLab formulations must have adequate
c a rr y o u t a ly t i c cyc le, replication cycles for large-scale production.

c aus i n g t he lys i s o r PHAGES

elimination of the MINEFIELD
bacteria, or a Mucous surfaces are the main area of contact
lys o g e n i c cyc le, between animals and the environment, so they
represent the main point of entry for
where they pathogenic bacteria, which will colonize the
integrate their digestive tract, generating symptomatic
genetic material outbreaks.

into the genome of Considering this model, when the

the bacteria, without bacteriophages that make up PhageLab

products reach the intestine, they adhere to
eliminating it. the intestinal mucus, generating a "minefield"

3
against the bacteria that have colonized or

6
will colonize this organ.
PHAGELAB
C O C K TA I L OUR
PRODUCTS
At PhageLab we use
treatments based on lytic C A LV E S
bacteriophages or a mixture of them Our product for calf rearing is a food additive
against pathogenic bacteria. Bacteriophages designed to prevent infectious diarrhea caused
are ubiquitous viruses found primarily where bacteria exist. by E. coli and Salmonella Spp in lactating calves.

It is estimated that the total number of bacteriophages on the P O U LT R Y & S W I N E

planet exceeds a proportion of 1031 and that for each different We have developed a liquid application
bacterium there are 10 bacteriophages capable of infecting it. designed to eliminate the presence of
Salmonella in broilers and E. coli in swines in
intensive rearing processes.