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Universal Access To Preferred Primary PCI For STEMI in Malaysia: It Is Time To Roll - Out A Sustainable Primary PCI Program
Universal Access To Preferred Primary PCI For STEMI in Malaysia: It Is Time To Roll - Out A Sustainable Primary PCI Program
Universal Access To Preferred Primary PCI For STEMI in Malaysia: It Is Time To Roll - Out A Sustainable Primary PCI Program
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“I’ve got to defend my children, and yours, and do what’s right health facilities, there is currently no mechanism to ensure that
to save lives… Obesity (STEMI) kills. There’s no question it everyone could access the appropriate medical care without
kills… People are dying every day. This is not a joke. This is any worries about reimbursement or ability to pay.8 Some
about real lives.” ~ Mayor Michael Bloomberg.1 patients have to join long waiting queues and some acute
emergencies are offered sub-optimum therapies for want of
Our Disparate Access to Healthcare better expertise or amenity.
Malaysia is a middle-income economy in South-East Asia,
aspiring to become a fully developed nation by 2020. It has a Clearly we must consider embarking on a national program for
population of 30 million, of which some 70% live in urban greater health equity. But this should be achieved without
locations. Yet despite this aspiration to become fully economically burdening the public any more than it has thus
developed, both economically and also in terms of human far.9 Undoubtedly, legislative policy and regulatory
development, Malaysia has faltered in more ways than one. We frameworks need to be consistently and properly planned to
certainly can do much better. ensure better resource management of public funds, as well as
to rationalize private spending patterns.10 Note too that while
It is true that our primary health care system is among the best most nations enforce some sort of prepayment options and risk
in the world, one that is praised by W.H.O. and emulated by pooling reimbursement mechanisms,11 any new plan that
other less developed nations of the third world.2 But on the side demands or mandates more personal taxes or social/health
of tertiary healthcare, we appear to have stalled. On the one insurance premium contribution would be adversely received,
hand, we have all the state-of-the-art amenities and expertise if not downright rejected! A realignment and/or an increased
for almost every serious ailment including non-communicable reallocation of already budgeted public funds would be the way
diseases such as coronary artery disease and cancers; yet we forward. It is sobering to look at the newly imposed GST that
are grappling losing battles with rising cardiovascular diseases, has been roundly condemned as a regressive tax that is
hypertension, diabetes, obesity as well as communicable burdening the poorer segment more than the rich!12
diseases such as dengue, influenza and multi-drug resistant
tuberculosis.3,4 Unfortunately in Malaysia, most of the treatment pathways for
major illnesses have been defined by one’s ability to pay, i.e.
But for many, diagnostic and therapeutic services are still those with means, health insurance or with third party payer
rather sporadic, inconsistent and not uniformly accessible. options for reimbursement are those who can afford to seek
There are wide differences in service availability or quicker and timelier access to medical care at private health
accessibility among urban, suburban and rural-riverine facilities. Unfortunately this accounts for just around 14% of
communities, as well as intra-city disparities.5 Most of the the population as shown by our national health accounts data.13
urban areas are clearly very well equipped, but this does not As many as 37% or so pay out of pocket. On the other hand,
necessarily translate down into universal access and uniform Malaysians with more limited funds have little choice but to
medical care for everyone. Sadly there is a wide chasm of seek treatment at the hugely-subsidized or low-cost point-of-
service public
amenities, which are
already bursting at the
seams of demand
overload.14 For the
acute treatment of
some conditions,
speedy and universal
access to any
healthcare facility is a
must, if we are to
achieve a fair
modicum of best
practices in health care
as expected of a
modern state.
health outcomes being highest (worst) among the lowest Our less than stellar management of STEMI
income group when compared with the highest income group. The lacklustre treatment of heart attacks or ST-elevation
(See Table 1)6 A gap of nearly 14 to 19 years (male vs. Myocardial Infarction (STEMI) comes to mind when we
female) for life expectancy at birth between the lowest to the examine our NCVD data.15 Here, we have not progressed as
highest income group is unacceptable, and inequitable for a much as we would like to have. The majority of our acute
‘developed’ nation status! coronary syndromes especially STEMI are still treated with
medical only therapy or the less-than optimum fibrinolysis in
The sad aspect of our health system is that we are still stuck in 70% of the cases, with less than 10% being offered primary
the past, with no declared universal access to healthcare for all angioplasty (Primary Percutaneous Coronary Intervention or
our citizens and residents.7 Even if we accept that no one is PPCI). Another 20% or so receive no targeted treatment due to
ever turned away from treatment at most public hospitals and missed diagnosis or delay in first medical contact (FMC).
Malaysia’s Health Service under pressure… multiple factors: some from misdirection as to costs, but mostly
Malaysia spends a total of USD 12 billion per year (latest because of logistics mismatch, many of Malaysia’s heart attack
MYR 42.3 billion, 2012)13 on healthcare expenditure, through a patients still do not receive the best possible care i.e. timely
mixed reimbursement health system. The public-funded health primary angioplasty.
system caters to the bulk of the population. About 55% of the
total health budget comes from the public purse through tax So, as many as 70% of heart attack patients are only able to
revenue allocations, and are used to defray 70% of total access and receive fibrinolytic therapy (‘clot-busting’ therapy);
hospital admissions, as well as 30% of the total number of currently considered a second best option. Some 20% receive
primary care outpatient services. The other 45% of the no proper targeted treatment because of delay or access
country’s total health expenditure is provided by the private issues.15 Only 10% have access to primary angioplasty, which
sector on a fee-for-service mechanism, the bulk of which are is now globally regarded as the treatment of choice. Primary
through third-party-payer mechanisms including health angioplasties for heart attacks are projected to nearly halve the
insurers and employer-provided/subsidized Managed Care risk of death during hospitalization (4% vs. 7%), and over the
Organizations (MCOs).10 first year (7% vs. 12%) when compared to other treatment,
especially when these are carried out at accredited centres.18,19
Thus, wide disparity in timely access to the most advanced
forms of medical care is the norm in Malaysia. While basic At the current time in Malaysia, there is no national program to
health services are readily and universally accessible, tertiary address the issue of primary angioplasty as first choice for
and more advanced care is still sporadic and inconsistent, treatment of heart attacks (STEMI). The government-funded
depending to a large extent on locale, proximity, availability of public sector has always maintained a hands-off approach to
amenities/expertise and costs (who’s paying). By and large the coordinating or sharing of services with the private sector,
public sector provides a more limited and constrained basket of presumably because priorities elsewhere demand their greater
services, based on tight finite budgets, and more queue-based attention! Yet, there have been many areas and precedents
prioritization of needs and costs. Conversely the private sector where public-private sharing and cross-referrals have taken
provides facilitated access to more advanced technology and place, i.e. the shorthanded oncology and neurosurgical
modern state-of-the-art medical therapies on the basis of disciplines that regularly employ private specialists.
capacity of reimbursement, either via third party payers
(including self- or employer-provided health insurance Recently Institut Jantung Negara (IJN) our National Heart
schemes) or out-of-pocket means. Institute, has embarked on a collaborative strategy to involve
the Kuala Lumpur Hospital to strategize more timely referrals
Cardiology Services: public, academic vs. private of STEMI to its nearby facility. Furthermore, cardiology
Let’s consider a more focused area, i.e. Kuala Lumpur our services officials from the Ministry of Health for the Selangor
captial city. Greater Kuala Lumpur (‘the Klang Valley’) has 21 and Kuala Lumpur area have agreed on a more streamlined
cardiology centers with catheterization laboratories that can approach to refer STEMI patients to some public and academic
offer expertise and access for primary angioplasty for heart cardiac centers for PPCI where appropriate.
attacks. However of these 21 centers, only 5 are public sector
health facilities that are heavily subsidized for reimbursements Alas, private establishments have been omitted because of
of all health care costs. The other 16 centers are private concerns about reimbursement uncertainties. Sadly therefore,
hospitals that provide tertiary medical care on a fee-for-service this leaves out a chunk of the available private facilities and
model. However, only 12 of these 16 private medical centers expertise that can perform PPCI in a more efficient manner.
provide routine tertiary cardiology care and primary However, not long after these strategies have been mooted, the
angioplasty services. 16 About half of the 200+ accredited Health Ministry started issuing cost-cutting directives about not
specialist cardiologists in the country are located in the Klang referring patients across public-academic platforms, because
Valley, who are credentialed to perform angioplasty. this would increase costs for the federal government. The
reasons given were economic: budget cuts, belt-tightening to
But when it comes to seeking urgent treatment for STEMI, the mitigate our looming recession and address our runaway
luck of the draw determines who and where you are presented budget deficit concerns!20
to, especially for those without any prepayment plans of
reimbursement. The bulk of newly incident STEMI patients are Therefore, for heart attacks occurring among the public, there
referred to public centers where the overloaded system cannot is an implicit practice, based on some intra-governmental
guarantee the best approach possible, so it’s either just medical directive, for patients to be referred directly and only to the
therapy or fibrinolysis based on timing and availability. public medical centres. Such a practice or directive is however
shortsighted and inefficient, because it is fraught with logistic
It is sobering to note that Myocardial Infarction is still the
anomalies: more often than not, transfer and access is either
primary cause of death (30% of all deaths) in Malaysia for the
delayed, or in many cases, not available at all. This mismatch
past 35 years, over and above communicable infections and
of need vs. demand is due predominantly to limitations or
cancers. Heart attacks or ST-Elevation Myocardial Infarctions
constraints of bed- or CCU-availability, lack of available
(STEMI) are increasingly common and represent a serious
expert personnel, accustomed non-cardiologist physician-
cause of death in Malaysia, particularly in the major urban
decision bias, or perceived higher costs at private centers.
areas. Cardiovascular Diseases (CVD) accounted for 244,472
Therefore, for the capital city of Kuala Lumpur despite its
admissions or 7.44% of total admissions to Malaysia’s public
and private hospitals in 2012. In 2012, CVD accounted for higher GDP, there are not enough concerted efforts to organize
some 25.1% of all deaths among hospital admissions in the a coordinated response to address this issue of delay in access
to this lifesaving procedure.
country.17
So how can we achieve or perform better for STEMI Suboptimal Choice of Fibrinolytic Therapy: Of course, there
management? STEMI is best treated with early and timely is still a place for fibrinolytic therapy based on our curent CPG
primary angioplasty to re-open clogged-up heart arteries, to guidelines for STEMI. But this should not be the default first
help save and preserve heart muscle and function. PPCI has choice.21 Used as default first line therapy, many patients who
been shown to save more lives. Unfortunately because of could have been better treated with primary angioplasty, would
be denied this preferred mode of therapy. While also beneficial associated with unaffordable higher costs. Thus, most heart
when compared to no treatment at all, fibrinolytic therapy has attack patients are either self-referred or are preferentially
been shown to be inferior to primary angioplasty in short and channeled to ‘cheaper’ public hospitals and facilities by
long term results, in residual morbidity outcomes and even default. This is also true when ambulance services are called
deaths.22 Survival data suggest that primary angioplasty upon for emergency transfer. These default transfers have been
reduces by half the one-year mortality rate that which is known to cause great strains on the limited resources of these
achievable with fibrinolytic therapy, and that return to work heavily subsidized public centers, and result in bottlenecks of
and life functionality, quality of life is also superior. Cost- delayed or suboptimal care. Thus, we also need to address this
effectiveness measures also favor primary angioplasty in terms issue of engaging emergency and ambulance services as well
of longer-term costs of therapy and economic loss analysis.23 as primary care practitioners to enlighten them that we now
have a more concerted and integrated approach to optimum
According to our NCVD database, as many as 7-10 percent of STEMI therapy, regardless of costs.
heart attack patients in Malaysia still perish within the first 7
days of hospitalization (the rate for best global standards is So what can be done about the costing issue?
now around 5%); with the 30-day mortality rate ranging from
11-14 percent. The first year mortality rate averages 15-18 The Rationale of Bridging the Private-Public Gap
percent.15 These do not reflect the best practices achievable Is this current public-private dichotomy of care, and lack of
elsewhere, unfortunately. coordinated access viable or sustainable? Or can this be
mitigated? In West Jakarta, Indonesia, there is now an ongoing
Perhaps it is time to enact a pradgim shift in our dichotomous coordinated project (both public and private facilities) that
approach to treating STEMI for Malaysians. Could we not integrates all PCI-capable centers to engage in the best
establish and coordinate a program to help educate, facilitate optiumum treatment for STEMI.26
access, transfer as well as to integrate the various facilities to
ensure that as many people as possible with heart attacks can One suggestion for us here in Malaysia, is to set up a not-for
achieve this goal of timely access and therapy at the lowest profit but self-funding private-public financed corporation/
costs and best utilization of current resources, as best as consortium to develop a working cost-effective model and
possible? It is certainly doable if some common vision and integrated proposition to the health authorities. But we also
mission can be established to realize this win-win strategy for need buy-ins from healthcare payers (insurers, third party
all, especially for all our patients. payers, employer-health schemes, public sector health cost
allocation) on how to develop and execute a comprehensive
A Greater Kuala Lumpur Area/Klang Valley STEMI PPCI seamless system to ensure the best care for heart attack patients
Project? i.e. coordinated transfer of patients, providing well-trained
We could pilot this project to include all of Greater Kuala personnel, consistent and routine access to coordinated
Lumpur area or the Klang Valley, which has the metropolitan pathways, i.e. organizing cathlabs (cardiac catheterization
population of about 6.9 million, as of 2010. laboratories) to operate 24/7 for acute PCI, seamless structural
admission/registration mechanisms and integrated approaches
Costs of therapy: Since costs has always been a bugbear in including reimbursement models for timely primary
health access, we need to resolve this issue once and for all. angioplasty. The goal is for this improved system to be rolled
Treating a heart attack in the Klang Valley by primary out for action within a year or as soon as possible.
angioplasty costs approximately MYR 30,000 for a daytime
procedure with a single stent, standard medications, and a Social Impact Bonds: Possible Financing Model
routine uncomplicated hospital stay of 3-4 days.24 Care Recently there have been some touted new models of joint
requiring coronary artery bypass surgery (CABG) or during Public-Private Financing Initiatives, not just based on for-profit
off-office hours emergency setting can cost up to twice or three ventures, but also for social causes. This came about when
times as much, with an additional cost of MYR 8-10,000 per Corporate Social Responsibility (CSR) and grant giving are
additional stent used. Medical treatment of heart attacks using seen as one-off contributions that often do not see committed
fibrinolytic therapy costs an average of MYR 12,000 for the or measurable outcomes. So how about creating possible
acute hospital stay of 3-4 days, if the cheaper streptokinase is higher-risk “Pay for Success” joint venture models to help
used, MYR 16,000 for tenectaplase. However, because of bring about more accountability and measureable results?27
expected increased rates of recurrent events and complications
utilizing the fibrinolytic method, the overall total economic
costs are estimated to be 4 to 5 times the total cost of primary
angioplasty in the longer term, per incident STEMI.