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burrhole cranio
burrhole cranio
RESULT
Question: 1
Siewert classification is used for?
A Esophageal cancer
B Stomach cancer
C GE junction cancer
D Periampullary cancer
Explanation:
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Question: 2
Which of the following is not a capsular plate of liver?
A Portal plate
B Hilar plate
C Cystic plate
D Umbilical plate
Explanation:
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Glisson’s capsule which covers the liver extends into the liver at the hilus and
covers the portal triad, where it is called Glisson’s sheath. Glisson’s capsule also
covers the Glissonian pedicles inside the liver. Couinaud called this sheath the
Valoean sheath, after Valoeus, an anatomist from the Middle Ages who first
described the liver capsule.
The plate system consists of bile ducts and blood vessels surrounded by a
sheath. There are three plates in the hilar area: the hilar plate, the cystic plate,
and the umbilical plate. The bile duct and blood vessel branches penetrate the
plate system and form Glisson's capsule in all segments of the liver, except for
the medial segment.
Question: 3
All of the following are correct regarding Emphysematous cholecystitis
except?
B D M is a risk factor
Explanation:
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Question: 4
Which of the following structure causes sharp pain while doing
abdominal surgery?
A Parietal peritoneum
B Liver parenchyma
C Small intestine
D Colon
Explanation:
Correct Answer (A) Parietal peritoneum causes sharp shooting somatic pain all
other structure cause visceral pain
Question: 5
A 32 year old patient presented with Jaundice, pruritis and clay coloured
stool. USG showed Gall stone and dilated CBD. Which of the following
finding is consistent with this condition?
A High unconjugated
bilirubin
C Increased GGT
D Positive urobilinogen in
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urine
Explanation:
Question: 6
A 70 year old male was admitted with large bowel obstruction and caecal
diameter of 12.5 cm. An urgent laparotomy was done and a completely
obstructing rectal cancer was found in upper 1/3rd of rectum. Patient is
hemodynamically stable with a known H/O of DM and HT which is well
controlled on medicatiion. What is the best treatment for this patient?
A Defunctioning colostomy
D Abdomino-perineal
resection
Explanation:
Question: 7
Spigelian hernia occurs at?
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Explanation:
Question: 8
False statement about RIRS is?
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C Done by flexible
ureteroscopy
Explanation:
Correct Answer (D) Ho: YAG laser is used for stone breaking not KTP laser RIRS
(retrograde intrarenal surgery): is a procedure for upper tract stones using
flexible fibreoptic endoscope. It is done in retrograde fashion i.e. through the
urethra into the bladder and then through the ureter into the urine-collecting
part of the kidney. It is approved for stones which are < 2cm in size and is
considered a good minimal invasive technique for pelvic and calyceal stones.
Question: 9
Surgery shown in the picture is done for?
A Pyelolithotomy
B PUJ obstruction
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D Extended pyelolithotomy
Explanation:
Question: 10
Which of the following is not a surgery for Hypospadias
B MAGPAI
C Matheus
D Foley’s Y V plasty
Explanation:
Question: 11
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Explanation:
Question: 12
Most sensitive investigation for DCIS is?
A MRI
B Mammography
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C USG
D CT scan
Explanation:
Question: 13
Not a feature of Lobular carcinoma?
C CDH 1 gene
Explanation:
Correct Answer (B) LCIS is more easily detected on Mammography then DCIS
Question: 14
Preferred treatment for medullary cancer thyroid is?
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B Surgery and
chemotherapy
D Only surgery
Explanation:
Correct Answer (D) Total thyroidectomy and central node dissection is the
standard treatment for medullary cancer.
Question: 15
False statement about secondary hyper-parathyroidism is?
B Associated
Hyperphosphatemia
C Hypercalcemia is a
consistent feature
Explanation:
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Question: 16
Malignant pheochromocytoma maximally produces?
A Dopamine
B Epinephrine
C Nor epinephrine
D Metanephrines
Explanation:
Question: 17
Varicose vein. Test for SFJ incompetence?
A Trendelenburg test
B Fegan test
C Tourniquet test
D Perthes test
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Explanation:
Question: 18
Nicoladoni Branham sign is seen in?
A AV fistula
B DVT
D Popliteal aneurysm
Explanation:
Correct Answer (A) Nicoladoni Branham sign is seen in AV fistula. When the
artery proximal to the fistula is compressed, blood is no longer shunted from
artery to vein side which leads to increased peripheral vascular resistance. This
causes relative hypertension and bradycardia. Locally, because no blood is being
shunted, the swelling reduces and bruit/thrill disappears.
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Question: 19
What is the treatment of open pneumothorax?
A IPPV
D Air-tight dressing
Explanation:
An open pneumothorax happens when air builds up in the pleural cavity, due to
a hole in the chest wall. It differs from a closed pneumothorax, during which air
enters the pleural cavity from the lungs themselves. An open pneumothorax can
occur as a result of direct trauma or could be iatrogenic.
An open pneumothorax is treated by applying a three-way dressing to the
wound, which involves taping the dressing on only three of the edges. The intent
is to prevent the individual from breathing in air through the opening in the
chest wall while allowing them to exhale air from their lungs. An inserted chest
tube will further assist the individual in breathing. If the dressing is not properly
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applied, and it allows air into the chest space without allowing it to escape, a
tension pneumothorax may develop.
Question: 20
False stamen about superficial 2nd degree burn?
A Painful
C Blisters found
D Heals by epithelization
from skin appendages
Explanation:
Correct Answer (B) Superficial 2nd degree burn heals in 2 weeks not 4 weeks.
Question: 21
Which cancer does not spread through neural sheath?
C Adenocarcinoma of
pancreas
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D Hepatocellular cancer
Explanation:
Question: 22
In post radical neck dissection shoulder syndrome all are seen except?
A Pain
B Restricted range of
movement
C Drooping of shoulder
D Weakness of deltoid
muscle.
Explanation:
Correct Answer (D) I radical neck dissection Spinal accessory nerve is sacrifice
which leads to denervation of trapezius called shoulder syndrome (not deltoid).
It leads to inability of abduction beyond 90 degree along with internal rotation,
long standing pain in shoulder and drooping of shoulder
Question: 23
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A Lung cancer
B Colon cancer
C Prostate cancer
D Breast cancer
Explanation:
Question: 24
Most common nosocomial infection is?
C UTI
Explanation:
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UTI
Question: 25
Identify the instrument?
B Gelpi Retractor
C Weitlaner retractor
D Gutow retractor
Explanation:
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Question: 26
A primipara wishes to know the symptoms of onset of labour. Which of
the following is the most correct answer to her question?
A Blood-stained mucous
vaginal discharge.
D Dribbling
Explanation:
Correct Answer (B) Colicky lower abdominal pain and backache which increase in
frequency, intensity and duration with time. The definitive symptom of labour is
colicky lower abdominal pain and backache which increase progressively. This
should be accompanied by progressive effacement and dilatation of the cervix.
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The pain is not relieved by common analgesics. Show or dribbling may or may
not be present at the onset of labour.
Question: 27
Which one of the following is not a sign of separation of placenta?
Explanation:
Correct Answer (C) The cord "lengthens", but recedes on pushing the uterus
upwards signs: 1-umbilical cord lengthens and it does not recede back when
uterus is pushed upwards. -The most reliable sign is the lengthening of the
umbilical cord as the placenta separates and is pushed into the lower uterine
segment by progressive uterine retraction. 2-gush of blood 3-firm/globular
uterus 4-uterus rises to the abdominal wall 5- supra pubic bulge
Question: 28
In deep transverse arrest, the head is arrested at the levels of:
A Ischial tuberosity
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B Ischial spine
C Inlet of pelvis
D Perineum
Explanation:
Correct Answer (B) Ischial spine it is the narrowest plane in the pelvis and the
baby is not able to pass through this station.
Question: 29
Which one of the following is the most practiced regime of antenatal
corticosteroid therapy for maturation of fetal:
A Dexamethasone 12 mg
daily for 3 days
B Betamethasone 12 mg 12
hourly × 2 dose
C Dexamethasone 6 mg 12
hourly × 4 dose
D Betamethasone 8 mg 8
hourly × 3 dose
Explanation:
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Question: 30
A 19-year-old comes to an adolescent clinic with complain of nausea and
vomiting. She did a home urine pregnancy test which was positive. She
does not remember her date of last menstrual period. US shows a viable
pregnancy of 8 weeks gestation. Which of the following statements
regarding first trimester ultrasound is correct?
B The accuracy of
determining gestational age using
ultrasound begins to decrease
after first trimester
Explanation:
Question: 31
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A third para, who had a normal vaginal delivery in her first pregnancy and
an upper segment caesarean section for transverse lie in her second
pregnancy, attends the antenatal clinic at 36 weeks. The presentation is
cephalic. The estimated fetal weight is 2.8 kg. The birth weight of the first
baby was 3.2 kg. There are no other pregnancy complications. What is the
most appropriate method of management?
Explanation:
Question: 32
An ultrasound scan is performed in a woman with a monochorionic
diamniotic twin pregnancy at 24 weeks. Bladder of one twin not visible
with oligohydramnios and there is polyhydramnios in the other sac.
Doppler studies are normal. What is the best management option?
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A Perform amnioreduction of
the sac with polyhydramnios.
Explanation:
Question: 33
Indications for caesarean section in pregnancy are all except:
A Eisenmenger syndrome
B Aortic coarctation
C Aortic aneurysm
D Aortic dissection
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Explanation:
Question: 34
In heart patient the worst prognosis during pregnancy is seen in:
A Mitral regurgitation
C Aortic stenosis
D Pulmonary stenosis
Explanation:
Correct Answer (C) Aortic stenosis Stenotic lesions are worse than regurgitant
lesions. Aortic stenosis has highest mortality amongst all the given options.
Eisenmenger syndrome has even higher mortality but that is not given in the
option.
Question: 35
Infants of diabetic mothers are likely to have the following cardiac
anomaly:
A Coarctation of aorta
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B Fallot's tetralogy
C Ebstein's anomaly
D Transposition of great
arteries
Explanation:
Correct Answer (D) Transposition of great arteries CVS anomalies are the most
common anomalies in the infants of the diabetic mothers. The most common
ones are VSD, TGA, endocardial cushion defects, etc.
Question: 36
A primigravida 32-year-old female is admitted to the antenatal ward at 35
weeks is found to BP of 160/110. Her urine does not contain albumin.
Which of the following drugs should not be used in her management?
A Furosemide
B Labetalol
C Nifedipine
D Hydralazine
Explanation:
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Correct Answer (A) Furosemide The drug of choice is labetalol. Furosemide must
not be given because it causes intra vascular dehydration and in this case, there
is already a reduced level of intra vascular volume.
Question: 37
All of the following increase in pre-eclampsia except:
A Uric acid
B Thromboxane A2
C sFIt-1
D VEGF
Explanation:
Correct Answer (D) VEGF Uric acid is raised due to reduced functions of kidney.
TXA2 and sFlt-1 are vasoconstrictors. VEGF is vasodilator and it is having
reduced activity in pre-eclampsia.
Question: 38
A 45-year-old woman presented with lower abdominal discomfort on
examination uterus appears uniformly enlarged and adnexa is free.
Histopathology of uterus shows endometrial glands inside the
myometrium. The diagnosis is:
A Adenomyosis
B Endometriosis
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C Leiomyoma
D Endometrial Hyperplasia
Explanation:
Question: 39
Ideal contraceptive for lactating mother is:
A Barrier method
B Combined OCP
C Lactational amenorrhoea
Explanation:
Correct Answer (D) Progesterone only pill Barrier has high failure rate, COCs will
reduce the milk output, LAM is a natural method with 5 % failure rate. POP will
be best for lactating mothers.
Question: 40
Peritoneum is opened in all of the following procedures except:
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A Mini laparotomy
B Laparoscopy
C Vasectomy
D Transvaginal tubectomy
Explanation:
Correct Answer (C) Vasectomy Vasectomy does not require opening of the
peritoneum. Other procedures require this step.
Question: 41
Contraceptive to be avoided in epilepsy:
A OCPs
B Condom
C IUCD
D Mirena
Explanation:
Correct Answer (A) OCPs COC pills are not given if patient is on anti-epileptic
medications because estrogen is an enzyme inducer and it reduces the amount
of anti-epileptic drug in the circulation.
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Question: 42
A mother brings her 19 years old daughter to your clinic with complaint
that she has not started having menses. General examination reveals
normally developed breasts and pubic hair. On pelvic examination,
vaginal ending is blind and uterus is not palpable. Which of the following
do you suspect?
A Mullerian agenesis
B Ashermann syndrome
C Gonadal dysgenesis
D Turner syndrome
Explanation:
Question: 43
Which of the following is the most common route of development of
genital tuberculosis?
A Hematogenous
B Lymphatics
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C Ascending infection
D Direct mode
Explanation:
Correct Answer (A) Hematogenous Lungs are the most common site from where
TB is acquired by the genital tract. Fallopian tube is the most common organ
involved.
Question: 44
True regarding testicular feminization syndrome:
Explanation:
Correct Answer (C) Genotype 46XY, phenotype is of female and gonads of male
it is a case of androgen insensitivity syndrome. It is the most common cause of
male intersex aka male pseudohermaphrodite. In this case, the genotype is male
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but the phenotype is female because there are no androgenic receptors. Testes
are present in the pelvis or in the inguinal canal.
Question: 45
Which of these is diagnostic of menopause?
Explanation:
Correct Answer (A) Serum FSH > 40 IU/L Menopause is a case of ovarian failure.
In this case, the follicles are depleted and so the estrogen and progesterone
levels are reduced. Due to this, there is an increase in the levels of FSH and LH. It
is a case of hypergonadotropic hypogonadism. Biochemical definition of
menopause will be Sr. FSH >=40 IU/L.
Question: 46
HRT is helpful in all of the following except:
A Vaginal atrophy
B Flushing
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C Osteoporosis
Explanation:
Correct Answer (D) Coronary heart disease HRT is not useful in preventing
coronary heart disease. It is responsible for an increase in the risk of
thromboembolic phenomenon.
Question: 47
A young lady presents to your office with complain of copious vaginal
discharge, but there is no cervical discharge on per speculum
examination. Which of the following should be given for the
management?
A Metronidazole and
fluconazole
B Metronidazole and
azithromycin
C Metronidazole and
doxycycline
D Fluconazole only
Explanation:
Correct Answer (A) Metronidazole and fluconazole The most common vaginal
infections are anaerobic, fungal and protozoal. The combination therapy of
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Question: 48
A 55-year-old woman was found to have Ca cervix, FIGO stage 2B. What
would be the management?
B Radiotherapy plus
chemotherapy
C Chemotherapy
Explanation:
Question: 49
Nulliparous women have high risk of following cancer:
A Cervical cancer
B Vaginal cancer
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C Ovarian cancer
D Endometrial Ca
Explanation:
Correct Answer (D) Endometrial Ca The best answer is endometrial cancer. Less
progesteronic exposure is surely a high risk of endometrial cancer. Multiparity is
protective for endometrial cancer.
Question: 50
The reference part in POP -Q classification is:
A Hymen
B Internal os
C Ischial spine
D External os
Explanation:
Hymen
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Question: 51
Which of the following is not true regarding ferroptosis?
B Mitochondrial shrinkage
C Pyknosis
Explanation:
Question: 52
Which of the following collagen types is seen predominantly in keloid?
A Type I
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B Type IV
C Type III
D Type II
Explanation:
Correct Answer (A) Type I. In keloid there is have haphazardly arranged normal
collagen [type 1>type 3]. In hypertrophic scar there is delayed maturation of
collagen from type 3 to type 1 thus type 3>1 in HS.
Question: 53
Which of the following is not feature of severe combined
immunodeficiency?
B Shrunken Spleen
C Absent Immunoglobulins
D Hypoclcemia
Explanation:
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Question: 54
What is likely diagnosis in this patient?
A Amyloidosis
D Malignant hypertension
Explanation:
Correct Answer (B) The image shows Nutmeg liver caused due to congestion in
liver. Right heart failure is a cause of the same.
Question: 55
Which of the following disease is due to paternal disomy of chromosome
15?
A Angelmann syndrome
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C Beckwith Widemann
Syndrome
D A& C
Explanation:
Question: 56
Which of the following is not true for grade of tumor?
B It tells prognosis
C Based on histology
D Chemotherapy is based on
grade
Explanation:
Correct Answer (A) Stage tells extent of spread not grade. Grade tell the
differentiation of the tumor.
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Question: 57
All the following are true about paroxysmal nocturnal hemoglobinuria
except?
C Thrombosis
D Thrombocytopenia
Explanation:
Question: 58
A patient underwent gastrectomy 4 months back and has developed
anemia now. Likely diagnosis?
A Vitamin B12
B Iron
C Folic acid
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Explanation:
Correct Answer (B) Gastrectomy can lead to both iron and Vitami B12 deficiency.
But B12 deficiency takes 1-2 years to set in while iron deficiency sets early thus
IDA is answer.
Question: 59
Peripheral blood smear of patient presenting with early fatigue and fever is
as follows. What is likely diagnosis?
A Infectious mononucleosis
B B-Chronic lymphocytic
leukaemia
C Sezary syndrome
Explanation:
Correct Answer (D) Hairy cell leukaemia. Image shows cells with hair like
projections seen in HCL.
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Question: 60
What is role of thrombomodulin in hemostasis?
A Activate fibrinogen
B Activate factor V
C Activate protein C
Explanation:
Question: 61
Histological image of Myocardial infarction shows coagulative necrosis
along with dense neutrophilic infiltrate. What is likely age of infarct?
A <1 day
B 1-3 days
C 5 days
D >1 week
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Explanation:
Correct Answer (B) 1-3 days. In < 1 days only necrosis is seen without
neutrophils.
Question: 62
Obstruction in emphysema is due to?
B Collapse of terminal
bronchiole due to loss of elastin
D Destruction of cartilage
due to infection
Explanation:
Question: 63
Sarcoma expressing cytokeratin is?
A Rhabdomyosarcoma
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B Osteosarcoma
C Fibrosarcoma
D Synovial sarcoma
Explanation:
Correct Answer (D) Synovial sarcoma. Synovial sarcoma is biphasic showing both
malignant mesenchymal and epithelial components, it shows positivity to CK
and also shows lymphatic spread.
Question: 64
ER+ PR+ Her2 Neu +++ tumors are classified as?
A Luminal A
B Luminal B
D Basal like
Explanation:
Luminal B.
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Question: 65
Which of the following does not have the histological image as shown on
biopsy?
B Lupus nephritis
C Wegners Granulomatosis
Explanation:
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Correct Answer (A) Minimal change disease. The image shows cresents in
glomeruli and minimal doesnot present with cresentic GN.
Question: 66
A completely unimmunised aged 24 months comes to you at the
immunisation centre. Which of the following vaccines under the National
Immunization Schedule (NIS) won’t be given?
A BCG
B JE
C DPT
D MR
Explanation:
BCG Explanation
Group
BCG 1 year
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program)
IPV 1 year
Pentavalent 1 year
Rota 1 year
Measles 5 years
OPV 5 years
DPT 7 years
JE 15 years
Question: 67
Which of the following vaccines doesn’t follow open vial policy; that can’t
be used after 4 hours of opening of vial?
A JE
B Rota
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C IPV
D DPT
Explanation:
IPV
Explanation
Question: 68
In which coloured bag/ box would you discard a broken vaccine vial?
A White
B Blue
C Red
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D Yellow
Explanation:
Blue
Question: 69
Which is the program providing zero denial to patients at time of delivery
at government facilities?
A MusQan
B SUMAN
C SAPNA
D PMMVY
Explanation:
SUMAN
Question: 70
Under NBSU number of beds available for paediatric care is?
A 5
B 10
C 20
D 30
Explanation:
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20
Question: 71
Which of the disease does have a 2nd attack?
A Mumps
B Measles
C Rubella
D Chicken Pox
Explanation:
Correct Answer (D) Chicken Pox Explanation Classically we don’t report 2nd
attack from any of the 4 stated diseases as they provide lifelong immunity but
now, we are getting few cases of chicken pox in adults who had suffered in
childhood as well.
Question: 72
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A pregnant female had got bitten by her own pet dog (a 11-month-old
puppy) 1 month back and had taken full course of rabies vaccination; has
not again got bitten by a monkey now. What is the line of management
now?
B Give Ig again.
D Do nothing.
Explanation:
Do nothing.
Explanation
Nothing must be done as the duration of re- exposure is only one month.
Question: 73
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A Income of family
B Income of HOH
C Education of HOH
D Occupation of HOH
Explanation:
Income of HOH
Question: 74
Mitigation in disaster cycle refers to:
A Triage
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C Mock drills
D Prompt management
Explanation:
Explanation
Question: 75
Identify the logo:
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A Ujala
B Ujjwala
C Ujjawala
D Ujjaawala
Explanation:
Ujjwala
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Question: 76
Jan Arogya Yojna provides a health insurance of INR ____ lakhs / year to
BPL families in a year:
A 1
B 2.5
C 5
D 7.5
Explanation:
Correct Answer (C) 5 Explanation PMJAY: • Cashless & paperless access (both
private & public) • States are free to choose the modalities for implementation
(implement through insurance company or directly through trust/ society or
mixed level) • Benefits are portable over the country. • Increased benefit cover to
nearly 40% of the population • Covering almost all secondary and many tertiary
hospitalizations (except a negative list) - 1,393 procedures • Coverage of 5 lakh
for each family (no restriction of family size, age, or gender) • All pre–existing
conditions are covered. • Covers cost of hospitalization, treatment, up to 3 days
of pre-hospitalization and 15 days of posthospitalization follow-up care
Question: 77
Calculate the TFR for this population:
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A 0.25
B 0.5
C 0.75
D 1.0
Explanation:
Correct Answer (B) 0.5 Explanation TFR = (Sum total of ASFR * Interval in Each
Age Group)/ 1000 TFR = (100 * 5)/ 1000 = 0.5
Question: 78
Which of the following disease is not spread by sandfly as a vector?
A Chandipura encephalitis
B Oraya fever
C Sandfly fever
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Explanation:
Question: 79
Which is not true for Focussed Group Discussion (FGD)?
A 6- 12 participants.
C Should discuss on a
common issue.
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Explanation:
Question: 80
Survival rate is used of all except:
A Cancers
C Common cold
Explanation:
Correct Answer (C) Common cold Explanation Common cold has no mortality so
SR or CFR will have least use for it
Question: 81
This clinical examination is not useful in which of the following conditions
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B Carotico-cavernous fstula
C Entropion
Explanation:
Question: 82
A 2yr old child brought by the parents with complaints of enlarged eyes.
There was no other complaint. IOP was normal. Cornea was clear. Rest of
eye examination was also normal. Most probable diagnosis is?
A Congenital glaucoma
B Retinoblastoma
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C Congenital endothelial
dystrophy
D Megalocornea
Explanation:
IOP normal rules out congenital glaucoma Cornea clear rules of endothelial
dystrophy Eye examination was norma, so retinoblastoma ruled out
Question: 83
These spectacles are useful in following except
A Myopic astigmatism in 16
year old
B Accommodative esotropia
in 2 year old child
C Pediatric pseudophakia of
1 year old child
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Explanation:
Correct Answer (A) Bifocal spectacles (executive type) Myopic astigmatism does
not need bifocals It requires spherical and cylinder lenses
Question: 84
A patient presents with abnormal facies, frontal baldness and with weakness
of the hands and difficulty in walking. He has difficulty in releasing grip,
muscle wasting and weakness. Ocular signs include all except?
A Ptosis
B Pigmentory retinopathy
C Subluxated lens
Explanation:
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Myotonic dystrophy
Question: 85
Identify
A Vossius ring
B Pseudoexfoliation
C Foreign body
D Ocular trauma
Explanation:
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Question: 86
Where is the likely lesion here
D Optic chiasma
Explanation:
Question: 87
What could be the presenting symptom of a person with diabetic cystoid
macular edema
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Explanation:
Correct Answer (C) Macular edema will present with gradual painless vision loss
with metamorphosia as central retina is involved
Question: 88
-4.00DS with -1.00DC ×180 degrees. What is false?
B Compound myopic
astigmatism with the rule
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Explanation:
Question: 89
What will be the result if cold water is poured in right ear of the patient
D No nystagmus
Explanation:
Correct Answer (B) COWS Cold water in right ear induces left nystagmus left fast
and slow slow phase
Question: 90
What will be the pupil reaction if you shine light in right eye of this patient?
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Explanation:
Correct Answer (A) Left hypo and exotropia with ptosis Left 3rd nerve palsy Right
pupil will constrict but left doesn’t when we shine light in right eye
Question: 91
A 9-year-old boy is brought to the clinic by his mother for evaluation of
rash and sore throat. Two days ago, the patient returned home from
summer camp with a fever, sore throat, and rash on his extremities as
shown in the image. The fever has resolved, but the rash has continued to
spread. The patient has no chronic medical conditions and has received all
routine vaccinations. Vital signs are normal. Oropharyngeal examination
shows superficial ulcers on the buccal mucosa and soft palate but no
tonsillar enlargement or exudates. The infectious agent most likely
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responsible for this patient's condition is also associated with which of the
following complications?
B Keratitis
C Myocarditis
D Symmetric polyarthritis
Explanation:
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Question: 92
A 25-year-old primigravida has a stillbirth at 18 weeks gestation. Her only
symptom during pregnancy was pain in both knees and feet, which she
attributed to pregnancy-related weight gain and being "on my feet all
day" as an elementary school teacher. The pain lasted approximately a
week and resolved without medication. The patient was taking prenatal
vitamins daily, and her prenatal care was appropriate. Fetal autopsy
shows pleural effusion pulmonary hypoplasia, and ascites. Infection with
which of the following is the most likely etiology of the stillbirth?
A Enveloped, double-
stranded DNA virus
B Enveloped, single-stranded
RNA virus
C Gram-positive coccus in
chains
D Nonenveloped, single-
stranded DNA virus
Explanation:
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Question: 93
A 43-year-old man undergoes induction chemotherapy for acute myeloid
leukemia. Three weeks later, he is hospitalized with fever, cough, and
generalized weakness. On physical examination, crackles are heard over the
right upper lung. Chest x-ray reveals a dense infiltrate involving the right
upper lung lobe. Broad-spectrum antibiotic therapy is instituted. Five days
later, the patient is still febrile. Bronchoscopy with biopsy is performed and
the tissue samples from the bronchoscopy grow mold as shown in the
image. Which of the following organisms is most likely responsible for this
patient's current condition?
A Aspergillus fumigatus
B Candida albicans
C Cryptococcus neoformans
D Pneumocystis jirovecii
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Explanation:
Question: 94
All the following organisms are positive for the test shown in the image
except
A Cryptococcus neoformans
B Brucella abortus
C Campylobacter jejuni
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D Helicobacter pylori
Explanation:
Question: 95
A 4-year-old male child is evaluated in your clinic for recurrent skin and
respiratory infections. He has light skin and silvery hair Horizontal
nystagmus is present on eye examination. Peripheral blood smear
demonstrates giant cytoplasmic granules in neutrophils and monocytes.
The patient most likely suffers from which of the following disorders?
A Chronic granulomatous
disease
B DiGeorge syndrome
C Wiskott-Aldrich syndrome
D Chediak-Higashi syndrome
Explanation:
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Question: 96
A 24-year-old woman comes to the emergency department due to 2 days
of fever. The patient has no chronic medical conditions. drinks alcohol
occasionally. and does not use tobacco or illicit drugs. She is sexually active
and frequently travels for her work as a freelance journalist. Physical
examination is notable for mild scleral icterus and splenomegaly. Laboratory
findings are shown in the image. Which of the following infectious agents is
most likely responsible for this patient ‘s current condition?
A Plasmodium falciparum
B Schistosoma mansoni
C Toxocara canis
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D Trichinella spiralis
Explanation:
Correct Answer (A) This patient with fever. Icterus, splenomegaly and ring-
shaped parasites within red blood cells has malaria, which is caused by 4 main
species of Plasmodium {P falciparum, P vivax. P ovale. P malaria). The parasite is
transmitted by female Anopheles mosquitos during blood feeding. travels to the
liver where it infects hepatocytes. and then subsequently undergoes asexual
reproduction, which generates hepatic schizonts with thousands of daughter
cells (merozoites). The diagnosis is confirmed when peripheral blood microscopy
shows intraerythrocytic trophozoites with a "diamond ring" appearance.
Question: 97
Vector for Trypanosoma cruzi is
A Tsetse fly
B Triatome bug
C Phlebotomus fly
D Simulium fly
Explanation:
Vector for T. cruzi is Triatome bug (Kissing, cone nose, assassin and reduviid bug)
Tsetse fly – T. brucei
Phlebotomus fly – Leishmania
Simulium fly – Onchocerca volvulus
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Question: 98
A 10-year-old boy is brought to the emergency department alter
experiencing high fevers and chills for the last few days. He also
complains of dull pain just above his left knee. He has no history of
recent trauma other than minor scrapes to his knees and elbows while
playing outside. Physical examination shows point tenderness 3 cm above
the kneecap. There is no joint effusion. Radiographs show soft-tissue
swelling and a periosteal reaction over the lower end of the femur. Which
of the following organisms is most likely responsible for this patient's
symptoms?
A Enterococcus faecalis
B Staphylococcus aureus
C Staphylococcus
epidermidis
D Pseudomonas aeruginosa
Explanation:
Correct Answer (B) Osteomyelitis is an infection of bone and bone marrow that
occurs by 1 of 3 mechanisms: Hematogenous seeding due to an episode of
bacteremia Spread from a contiguous focus of infection. as occurs in an infected
diabetic foot wound Direct inoculation of bone, such as with a compound
fracture Hematogenous osteomyelitis occurs predominantly in children
[particularly boys) and most frequently affects the long bones. The tibia, fibula
and femur are most often involved. Adults who develop the condition are more
likely to have vertebral involvement and frequently have a predisposition to
bacteraemia due to risk factors such as IV drug abuse or indwelling vascular
catheters. Overall MCC is Staphylococcus aureus
Question: 99
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A Bacillary angiomatosis
B Bladder cancer
C Condyloma acuminata
D Hemolytic uremic
syndrome
Explanation:
Question: 100
Kanagawa phenomenon in Wagatsuma agar is exhibited by
A Vibrio cholerae
B Vibrio parahaemolyticus
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C Vibrio vulnificus
D Vibrio alginolyticus
Explanation:
Question: 101
A patient on Sofosbuvir should periodically estimate
A RFT
B LFT
C ECG
D EEG
Explanation:
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Question: 102
All of the followings are matched correctly, EXCEPT
A A
B B
C C
D D
Explanation:
Correct Answer (B) Nalmefene nasal spray approved for treating opioid
overdose, not for dependence Sotagliflozin---- SGLT-2 inhibitor useful for heart
failure Fezolinetant – NK3 antagonist, useful for vasomotor symptoms associated
with menopause Trofinetide – approved for Rett syndrome
Question: 103
Which one of the following medications inhibits fibrinolysis?
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A Aminocaproic acid
B Heparin
C Lepirudin
D Lepirudin
Explanation:
Question: 104
Which of the following antidepressant drug is contraindicated in patients
with history of seizure?
A Fluoxetine
B Bupropion
C Venlafaxine
D Mirtazapine
Explanation:
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Correct Answer (B) Bupropion causes adverse effects of seizure and anxiety,
hence contraindicated in epileptic patients
Question: 105
Match the following
Explanation:
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Question: 106
A 14-year-old boy returns from a Boy Scout backpack trip with foul-
smelling watery diarrhea. On further questioning, he admits to drinking
water from a mountain brook without first boiling it. Stool is sent for ova
and parasites, confirming the diagnosis of Giardia lamblia infection.
Which of the following drugs is appropriate treatment?
A Metronidazole
B Nifurtimox
C Suramin
D Mebendazole
Explanation:
Question: 107
Which of the following drugs is correctly associated with its clinical
application?
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A A
B B
C C
D D
Explanation:
Correct Answer (D) Ferrous sulfate – useful for microcytic anemia Iron dextran
useful in iron deficiency anemia, for macrocytic anemia supplement VIT B12 and
folic acid Filgrastim is the recombinant granulocyte colony stimulating factor
useful for neutropenia not for thrombocytopenia, for thrombocytopenia due to
cancer chemotherapy orelvekin (IL-11) is used Eltrombopag – useful in
thrombocytopenia
Question: 108
A pregnant female with history of asthma presented in third stage of
labour. Which drug is to be avoided in her?
A Carboprost
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B Misoprostol
C Oxytocin
D Dinoprostone
Explanation:
Question: 109
Which one of the following is a fully human monoclonal antibody?
A Rituximab
B Bevacizumab
C Adalimumab
D Tositumomab
Explanation:
Correct Answer (C) Adalim u mab- U- fully human Tositum o mab- fully mouse
Ritu xi mab- chimerical Bevaci zu mab – humanized
Question: 110
Which of the following is an action of a non-competitive antagonist?
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Explanation:
Question: 111
A fetus was found to have congenital heart block. What should be
evaluated in the mother?
A APLA Syndrome
C SLE
D Hemolytic anemia
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Explanation:
Correct Answer (B) Newborn with congenital heart block, born to mothers with
Sjogren's syndrome and SLE have these issues due to anti Ro/SSA antibodies
from mother
Question: 112
A child presents with high grade fever, inspiratory stridor and develops
swallowing difficulty and drooling of saliva within 4-6 hours. Along with
airway management, which of the following needs to be given?
A Nebulized Racemic
epinephrine
B Anti-diphtheria toxin
C
Corticosteroids/Conservative
D IV Ceftriaxone
Explanation:
Question: 113
In Cystic Fibrosis, the mutation affects which ion transport, which amino
acid, and is at which position?
A 508; phenylalanine; Cl
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B 708; tryptophan; Ca
C 708; tryptophan; Cl
D 708; phenylalanine; Cl
Explanation:
Correct Answer (A) DeltaF 508 is the most common mutation in cystic fibrosis in
caucasions and indians.
Question: 114
Regarding UTI in children, correct options
A Most common is
S.pneumoniae
Explanation:
Correct Answer (B) In girls of 5-10 yrs, bowel bladder dysfunction adds to the
VUR and leads to recurrent UTI
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Question: 115
Not Useful in the management of GBS
A Plasmapheresis
B IV Immunoglobulins
C Steroids
D Ventilatory Support
Explanation:
Question: 116
A 3 week neonate presents with ambiguous genitalia with Na+ - 127, K+ -
5.6meq, along with IV fluids, what specific management is done?
A Calcium gluconate
B Potassium resins /
sequestration
C Hydrocortisone iv
Explanation:
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Question: 117
What is the most common cause of CAH in children?
A 21 hydroxylase deficiency
B 11beta hydroxylase
deficiency
C 17 alpha hydroxylase
deficiency
Explanation:
Question: 118
Age at which handedness develops?
A 2 years
B 3 years
C 4 years
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D 5 years
Explanation:
Question: 119
A 10 yrs old child with generalized edema has urine protein 3+ & serum
cholesterol 238mg/dl. His urine examination shows oval fat bodies What
is the most likely diagnosis?
A Nephrotic syndrome
B Nephritic syndrome
C Goodpasture syndrome
Explanation:
Question: 120
What is the first and best treatment for a frequent relapser nephrotic
syndrome?
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B Levamisole
C MMF
D Cyclophosphamide
Explanation:
Correct Answer (A) First and best step for frequent relapser or steroid dependent
nephrotic is low dose, long term alternate day prednisolone 0.5-0.7mg/kg/day
Question: 121
A patient of head injury has bluish discoloration over mastoid area,
bleeding from EAC and complaining of hearing loss with normal facial
nerve function. After three days, patient starts having facial weakness.
What is the possible diagnosis?
A Longitudinal fracture of
temporal bone
B Transverse fracture of
temporal bone
C Traumatic perilymphatic
fistula
D Traumatic fracture of
parietal bone
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Explanation:
Correct Answer (A) Longitudinal fracture of temporal bone Ref: Read the text
below Sol: • This is a case of longitudinal fracture of temporal bone. The ear
bleeding is a feature of longitudinal fracture. This fracture is due to fall on the
side. Battle sign is ecchymosis around the mastoid tip area which is seen in
temporal bone fractures. This fracture causes ossicular dislocation and hence
conductive hearing loss. Transverse fractures lead to cochlear injury and hence
cause SNHL. CSF otorrhoea is more common with longitudinal fractures • In
temporal bone fractures, the facial palsy is either of immediate (Transverse
fractures) or delayed onset ( Longitudinal fractures) • Immediate onset need
immediate surgery which is facial nerve decompression and if need be end to
end anastomosis or nerve grafting • Delayed onset should be managed with 3
weeks of steroid therapy as the cause is oedema in this case. If there is no
recovery after 3 weeks of steroid therapy, electrophysiological nerve testing
should be done (Electroneuronography). If there is significant facial nerve
degeneration, patient should be taken for surgery (facial nerve decompression)
should be done.
Question: 122
A 5 year old patient presents with the history of hearing loss. On
examination he is found to have a chalky white mass behind the intact
tympanic membrane as shown in the image . What is the most possible
diagnosis?
A Congenital cholesteatoma
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B Otomycosis
C Otosclerosis
D Exosteosis
Explanation:
Correct Answer (A) Congenital cholesteatoma Ref: Read the text below. Sol:- •
Congenital cholesteatomas are believed to arise from embryonal inclusions or
rests of epithelial cells. • Levenson, established a set of criteria for the definition
of congenital cholesteatoma in the middle ear. • These criteria included, (1) a
white mass medial to a normal tympanic membrane, (2) a normal pars flaccida
and pars tensa, (3) no prior otologic procedures. In addition, prior bouts of otitis
media were not grounds for exclusion.
Question: 123
A 20 year old male patient has high pitch voice. His fiberoptic
laryngoscopy is normal. The clinician has advised him for speech therapy
in which he is asked to pho-nate while pulling the thyroid cartilage
downwards and pressing it backwards. What is the name of this
manoeuvre?
A Heimlich manoeuvre.
B Gutzmann’s manoeuvre.
C Muller’s manoeuvre.
D Valsalva manoeuvre.
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Explanation:
Gutzmann’s manoeuvre.
Question: 124
What type of tympanogram is given in the picture?
A Type A curve.
B Type B Curve.
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C Type C Curve.
D Type AD curve.
Explanation:
Type B Curve.
Question: 125
Arrange the auditory pathway in order from periphery to centre A. Eight
nerve B. Inferior colliculus C. Medial geniculate body D. Ventral / dorsal
cochlear nucleus E. Superior Olivary nucleus F. Lateral lemniscus G.
Auditory cortex
A A, D, E, F, B, C, G
B B, C, G, A, D, E, F
C E, F, B, A, D, C, G
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D A, D, E, F, C, G, B
Explanation:
A, D, E, F, B, C, G
Question: 126
Which of the following is the most commonly used adjuvant for recurrent
respiratory papillomatosis (RRP) among members of American Society of
Pediatric Otolaryngology (ASPO)?
A Bevacizumab (Avastin)
B Intralesional cidofovir
(Vistide)
C Celecoxib (Celebrex)
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D Interferon
Explanation:
Correct Answer (B) Intralesional cidofovir (Vistide) Ref:Read the text below Sol •
Specific recommendations have been made by the Task Force on RRP from
ASPO in regard to the use of cidofovir. • Informed consent must be obtained
from the patient’s parents because this drug is being used in an off-label setting.
Question: 127
A Child underwent tonsillectomy and after surgery shifted to recovery
room where he started bleeding and on examination a clot was seen at
the site of surgery. Next step in management will be ?
Explanation:
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Question: 128
Which of the following statements is true about inverted papilloma
arising from the lateral wall of nose?
A Polypoidal masses
resemble allergic nasal polyps
B Affects females in
adolescent period
D Treatment requires
maxillectomy with postoperative
radiotherapy
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Explanation:
Correct Answer (A) Polypoidal masses resemble allergic nasal polyps Sol : •
Inverted papilloma, which arises from the mucosa of lateral wall of nose, most
frequently affects males in the age group of 30-5O years. • Only 10-15% are
associated with malignancy. • Treatment is complete excision which amounts to
medial maxillectomy. • Post-operative radiotherapy is not necessary.
Question: 129
50 yrs old male presented with odynophagia, “hot potato” voice and
stridor.On examination diffuse swelling over the posterior pharyngeal
wall was seen. X-ray revealed increased retropharyngeal space. Most
suspected diagnosis is :
A Retropharyngeal abscess.
B Prevertebral abscess.
C Parapharyngeal abscess.
D Ludwig’s Angina
Explanation:
Correct Answer (B) Prevertebral abscess. Ref: Read the text below Sol: •
Prevertebral abscess presents with diffuse swelling while retropharyngeal
abscess presents with localized swelling.
Question: 130
Vocal cord fixation is most likely due to invasion of the
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A Conus elasticus.
B Quadrangular membrane.
C Paraglottic space.
D Broyle tendon.
Explanation:
Correct Answer (C) Paraglottic space. Ref: Read the text below Sol: • There are
multiple barriers in the larynx to cancer spreading, including the conus elasticus,
quadrangular membrane, and the Broyle tendon. • Vocal cord fixation is usually
a sign of paraglottic space invasion or arytenoid involvement.
Question: 131
All of the following are contents of the posterior triangle of the neck
except:
Explanation:
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Nerve to rhombideus
Occipital artery
Supraclavicular nodes
Third part of subclavian artery Part of subclavian vein Suprascapular artery and
vein Supraclavicular lymph nodes Three trunks of brachial plexus
Question: 132
A patient recovering from a traumatic injury to the face now finds himself
unable to chew his food. On physical examination, his jaw deviates to the
right side. The nerve that has been injured in this patient exits the skull
through which of the following foramina?
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A Foramen rotundum
B Foramen ovale
C Foramen spinosum
D Foramen lacerum
Explanation:
Correct Answer (B) Foramen ovale Ref: Read the text below Sol All the given
features indicate that Mandibular nerve is involved hence Foramen ovale is
correct
Question: 133
A 43-year-old male received a deep intramuscular injection two days ago
and now presents with difficulty walking. You note that his right hip
drops every time he raises his right foot. At which location did this
patient most likely receive his injection?
A Superomedial quadrant of
the buttock
B Superolateral quadrant of
the buttock
C Inferomedial quadrant of
the buttock
D Inferolateral quadrant of
the buttock
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Explanation:
Exp:-
All injections into the gluteal region should target the superolateral quadrant, to avoid
damage to the gluteal nerves and sciatic nerve. This patient is exhibiting the classic
"gluteus medius gait," i.e. the hip dips downward when the ipsilateral foot is lifted off of
the ground. This gait is observed when there is injury to the superior gluteal nerve or to
the gluteus medius muscle itself. The superior gluteal nerve is derived from the L4-S1
ventral rami and leaves the pelvis through the greater sciatic foramen above the level of
the piriformis. Injection in the superomedial quadrant of the buttock is likely to injure
this nerve.
Question: 134
A 5-year-old male demonstrates persistent food-seeking behavior He is
obese, and his mother reports thathe sometimes exhibits aggressive and
bizarre behaviors These clinical findings may be explained by a lesionin
which of the following hypothalamic nuclei?
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A Lateral
B Suprachiasmatic
C Supraoptic
D Ventromedial
Explanation:
Correct Answer (D) Ventromedial Explanation: The body's satiety center resides
within the ventromedial nucleus of the hypothalamus. The neurons heredetect
blood glucose elevations and signal satiety in response. Bilateral lesions of the
ventromedial nucleicause hyperphagia and obesity. Episodes of rage and/or
savage behavior are also sometimes noted. Themost common cause of such
lesions is tumor invasion, for example by a craniopharyngioma. Lesions of the
ventromedial nuclei are the cause of obesity in only exceedingly rare cases.
Question: 135
A patient presents to your office with right leg numbness. When he walks,
you notice that he lifts his right foot higher than he does his left, and that
his right foot slaps to the ground with each step. On neurologic exam,
you also ascertain that he is unable to evert the right foot. Which of the
following nerves has most likely been injured?
A Tibial
B Common peroneal
C Superficial peroneal
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D Sural
Explanation:
Correct Answer (B) Common peroneal Exp: Patients with common peroneal
nerve damage present with an equinovarus (plantarflexed and inverted) posture
of the affected foot due to paralysis of the peroneus longus and peroneus brevis
muscles (mediate foot eversion), paralysis of the tibialis anterior muscle
(mediates dorsiflexion), and paralysis of the extrinsic extensors of the toes. Injury
to this nerve also causes loss of sensation to the anterolateral leg. The classic
finding on gait exam in patients with common peroneal nerve injury is "foot
drop," where the affected leg is lifted high off of the ground while walking due
to an inability to dorsiflex the foot. The affected foot will also classically slap to
the ground with each step.
Question: 136
An 15-year-old girl comes to the psychiatrist because she pulls out her
hair in pathes when she is anxious or upset. She is taught to make a tight
fist whenever she has this impulse rather than pull out her hair. Which of
the following techniques is this?
B Extinction
C Flooding
D Desensitization
Explanation:
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Question: 137
30 year old gentleman has excessive sleep at work attributed to sleep
discomfort at night. He also has recent history of falling while partying
with friends. What are the other features that can be seen associated with
his condition?
Explanation:
Correct Answer (D) Paralysis with sleep awake junction hallucinations Excessive
sleep at work, sleep discomfort at night, history of falling while partying with
friends is suggestive of narcolepsy. In narcolepsy, we also get sleep paralysis,
and hypnagogic and hypnapompic hallucinations.
Question: 138
A 32-year-old woman presents to the psychiatrist. She states she is
depressed because she did this to her child. The infant has growth
retardation, microphthalmia, short palpebral fissures, midface hypoplasia,
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a short philtrum, a thin upper lip, and microcephaly. Which is the most
likely diagnosis of the mother?
A Bipolar disorder
B Major depression
C Hypochondriasis
D Alcohol dependence
Explanation:
Correct Answer (D) Alcohol dependence The features described in this clinical
scenario resembles foetal alcohol syndrome. • Fetal alcohol syndrome affects
about one third of all infants born to alcoholic women. • The syndrome is
characterized by growth retardation of prenatal origin (height, weight); minor
anomalies, including microphthalmia (small eyeballs), short palpebral fissures,
midface hypoplasia (under-development), a smooth or short philtrum, and a thin
upper lip; and central nervous system (CNS) manifestations, including
microcephaly (head circumference below the third percentile), a history of
delayed development, hyperactivity, attention deficits, learning disabilities,
intellectual deficits, and seizures. • The incidence of infants born with fetal
alcohol syndrome is about 0.5 per 1,000 live births. • Some studies suggest that
alcohol use during pregnancy may contribute to attention-deficit hyperactivity
disorder (ADHD).
Question: 139
A 25-month-old boy plays with a ball, which rolls under a couch. The boy
promptly crawls under the couch to retrieve the ball. According to
Piaget’s theories of cognitive development, which thinking process best
describes this child’s behaviour?
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A Object permanence
C Object constancy
D Sensorimotor stage
Explanation:
Correct Answer (A) Object permanence By 2 years of age, child passes throught
sensorimotor stage and finally learns that objects are permanent. Remember :
Object constancy : Margaret Mahler Concept Object permanence : Jean Piaget
Concept
Question: 140
A 35-year-old woman sees a psychiatrist for a chief complaint of
depressed mood. She begins psychotherapy and sees the physician once
per week. After 3 months of therapy, she tells the psychiatrist that she is
very afraid of him because he is so angry and irritable person. She
behaves as if this is true and that the psychiatrist will explode with rage at
any minute. The psychiatrist is not normally seen as an angry person and
is unaware of any anger toward the patient. Which of the following
defense mechanisms is this patient likely displaying?
A Distortion
B Blocking
C Isolation
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D Projection
Explanation:
Correct Answer (D) Projection Projection, involves the tendency to see your own
unacceptable desires in other people.
Question: 141
A 78-year-old woman with a history of coronary artery disease & diabetes
takes aspirin 150 mg, telmisartan 40, glimepiride 2mg and clopidogrel 75
once a day from last 5 years. She is being taken for an emergency
exploratory laparotomy. Possible side effects associated with her drug
history include all the following EXCEPT
A Bradycardia
B Hypotension
C Hypoglycaemia
Explanation:
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• BETA BLOCKERS
• NTG
• CCBS
• STATINS
• STEROIDS
• THIAZIDES
• POP
• ANTI EPILEPTICS
• THYROID MEDS
• ATT
• ART
Question: 142
The following drugs are predominantly metabolized by the liver:
A Propofol
B Cisatracurium
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C Esmolol
D Mivacurium
Explanation:
Question: 143
Cisatracurium is preferred over atracurium because?
B No histamine release
C Metabolism by Hoffman’s
elimination
Explanation:
Question: 144
Anesthetic gas with maximum respiratory irritation
A Halothane
B Enflurane
C Desflurane
D Sevoflurane
Explanation:
Correct Answer (C) Inhaled anesthetic agent which in pungent in odour are: •
Ether • Isoflurane • Desflurane (maximum) Pungent inhaled anesthetic agents
cant be used for induction of anesthesia.
Question: 145
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Question: 146
A psychiatric person hears sounds of daggers being sharpened, while
normal people around him do not hear anything. This is an example of
A Illusion
B Obsessive compulsive
behavior
C Hallucination
D Fugue
Explanation:
Question: 147
The usual fatal dose of Opium is
A 2 micrograms
B 2 milligrams
C 20 milligrams
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D 2 grams
Explanation:
Question: 148
Motorcyclist’s fracture is
A Ring fracture
D Comminuted fracture of
the vault
Explanation:
Correct Answer (B) Division of base of skull into two halves – an anterior and a
posterior
Question: 149
Smokeless gunpowder is composed of
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A KMnO4
B HCN
C Nitrocellulose
D Sulphur
Explanation:
Question: 150
Caloric content of ethyl alcohol is
A 4 cal/g
B 4 cal/cc
C 7 cal/g
D 7 cal/cc
Explanation:
Question: 151
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Arrange the following structures in skin in the order of top to bottom (from
most superficial to deepest)
1. Desmoglein
2. Hemidesmosomes
3. Collagen7
4. Laminin
A 1, 2, 3, 4
B 2, 1, 4, 3
C 2, 1, 3, 4
D 1, 2, 4, 3
Explanation:
Question: 152
A patient from Himachal Pradesh gets a thorn prick and subsequently
presents with a verrucous lesion. The diagnosis?
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A Sporothrix
B Chromoblastomycosis
C Eumycetoma
D Verruca
Explanation:
Question: 153
A child presents with the image shown. The diagnosis is?
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A Bullous impetigo
B SSSS
C Candidal intertrigo
D Scrofuloderma
Explanation:
Question: 154
Check the MDT schedule in adult leprosy and mark the correct options: A.
Rifampicin 600mg once a month supervised B. Clofazimine 300 mg once
a month supervised C. Dapsone 50 mg once a day unsupervised D.
Clofazimine 50 mg once a day unsupervised
A A, B, D are correct
Explanation:
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Question: 155
Arrange the following lesions in varicella in order of their time of onset in
the infection ( from earliest to last) 1. Crust 2. Vesicle 3. Pustule 4. Papule
A 1, 2, 3, 4
B 2, 1, 4, 3
C 2, 4, 3, 1
D 4, 2, 3, 1
Explanation:
Question: 156
Cytosine in DNA is deaminated, the uracil residue that results may be
removed by
A An endonuclease
B An exonuclease
C A glycosylase
D Polynucleotide ligase
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Explanation:
An endonuclease
Question: 157
Which one of the following sequences places the lipoproteins in the order
of most dense to least dense?
A
HDL/VLDL/chylomicrons/LDL
B
HDL/LDL/VLDL/chylomicrons
C
LDL/chylomicrons/HDL/VLDL
D
VLDL/chylomicrons/LDL/HDL
Explanation:
HDL/LDL/VLDL/chylomicrons
Question: 158
Why glucose is stored as glycogen
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Explanation:
Question: 159
Enzyme which is active in well fed state is:
A Carnitine palmitoy1
transferase 1
B Pyruvate carboxylase
D HMG lyase
Explanation:
Question: 160
A 10 year old boy presented with abdominal pain, muscle weakness and
fatigue. On investigations , serum lead levels were found increased in
blood . Activity of which of the following enzyme in the liver is increased :
A ALA synthase
B Ferrochelatase
C PGB deaminase
D Heme oxygenase
Explanation:
ALA synthase
Question: 161
A 40-year-old male meets with a RTA after rash driving his bike without the
helmet on. NCCT head shows.
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A SDH
B SAH
C EDH
D Cerebral contusion
Explanation:
EDH
The NCCT head shows a biconvex hyper-density in right frontal area suggestive
of extra-dural hemorrhage. Also visible is subperiosteal hemorrhage on right
side.
Question: 162
Identify the X-ray view shown.
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A Caldwell
B Water's
C Schuller
D Towne
Explanation:
Caldwell
Notice that only the frontal sinus and anterior ethmoidal sinuses are visible and
this is seen in Caldwell view.
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Question: 163
A 35-year-old female presents with dysphagia, regurgitation and weight
loss. What is the likely diagnosis?
B Achalasia cardia
C Malignancy
D Leiomyoma
Explanation:
Correct Answer (B) Achalasia cardia • Notice the abrupt tapering at the distal
end of esophagus. The esophagus also looks grossly dilated just proximal to
tapering. This is seen in Diffuse esophageal spasm. • Option A would have
corkscrew appearance • Option C will have irregular filling defect in lower or
middle part of esophagus • Option D will produce a local filling defect with
relatively smooth margins in any part of esophagus
Question: 164
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A Ureterocele
B Hydronephrosis
C Staghorn calculi
D Bladder calculi
Explanation:
Correct Answer (A) Ureterocele The given IVP shows bilateral cobra head
appearance of distal ureter diagnostic of ureterocele.
Question: 165
Gold standard investigation for sinuses is:
A X-ray
B MRI
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C CT scan
D PET scan
Explanation:
Question: 166
Early onset IBD which is refractory to treatment is due to deficiency of
which cytokine
A IL-1
B IL-6
C IL-10
D IL-12
Explanation:
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Question: 167
For diagnosis of IBS abdomen pain frequency of >1day/week should be
present for
A >1month
B >2 months
C >3 months
D >6 months
Explanation:
>3 months
Question: 168
A patient has Hepatitis B surface antigen (HBsAg) positive, Antibody to
HBsAg (anti-HBs) negative Antibody to hepatitis B core antigen (anti-
HBc) IgM negative, Anti-HBc IgG positive What is the next step in his
management?
B Liver biopsy
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D Tenofovir
Explanation:
Question: 169
A 45 year old woman presents with a 5-day history of pale stools and
dark urine associated with cramping epigastric and right upper quadrant
pains. Blood tests show elevated ALP and GGT. What would be your first-
line imaging investigation?
A CT pancreas
B MRCP
C ERCP
D Ultrasound abdomen
Explanation:
Question: 170
A 14 year old boy has behaviour abnormalities with tremors.On examination
brownish green coloured deposit at corneal periphery is observed as shown
in the figure.What is the likely etiology
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A Hemochromatosis
B Wilson disease
C Sydenham’s chorea
Explanation:
Question: 171
A 33-year-old man comes for donating blood. He is asymptomatic. On
further history he has never been vaccinated for hepatitis B. Serologic
tests reveal negative hepatitis B surface antigen (HBsAg) and positive
Anti HBs and IgG antiHBc. Which of the following conditions does this
serologic pattern represents?
A Previous hepatitis B
infection
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B Chronic hepatitis
C Acute hepatitis
D Precore mutant
Explanation:
Question: 172
A 20-year-old woman with past history of rheumatic fever has dyspnea.
On examination- loud S1 present, opening snap and mid diastolic
rumbling murmur heard at the apex. What is the cause of this
presentation?
A Mitral stenosis
B Mitral regurgitation
C Aortic stenosis
D Aortic regurgitation
Explanation:
Question: 173
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A HOCM
B Restrictive cardiomyopathy
C ST elevation Myocardial
infarction
D Tako Tsubo
cardiomyopathy
Explanation:
Question: 174
A 76-year-old woman has atrial fibrillation with history of hypertension
and diabetes. There is no valvular heart disease. Which of the following
would be the most appropriate antithrombotic regimen for this patient?
A Aspirin
C Apixaban
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Explanation:
Question: 175
A 40 year old patient has developed palpitations.Pulse:130 beats/minute,
irregularly irregular with positive pulse deficit. What is the likely cause of
patient’s tachycardia?
A Sinus tachycardia
B Atrial fibrillation
C PSVT
D Atrial flutter
Explanation:
Question: 176
A 40-year old woman presents with sudden onset palpitations. An ECG
done reveals narrow QRS complex tachycardia. The most likely diagnosis
is:
A Ventricular tachycardia
B Pre-excited tachycardia
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C Paroxysmal
supraventricular tachycardia with
aberrancy
D AV rentry tachycardia
Explanation:
Question: 177
A 36-year-old man has generalized swelling over the body. Urinalysis: 4+
protein, oval fat bodies, serum albumin 2.1 g/dL, Liver function tests:
normal, serum Low-density lipoprotein (LDL) 145 mg/dL; triglycerides 500
mg/dL (elevated).What is the likely cause of this patient presentation
B Hypothyroidism
C CHF
D Nephrotic syndrome
Explanation:
Question: 178
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A Add cyclophosphamide.
B Add cyclosporine.
C Add rituximab.
D Add tacrolimus.
Explanation:
Question: 179
A male patient history of hypertension ,diabetes and CKD. He is taking
Lisinopril, amlodipine, Linagliptin and Gliclazide. On examination- BP:
150/96 mm Hg. Lab tests- serum creatinine 4 mg/dL; potassium 4.9
mEq/L;HbA1c 8 %, urine dipstix - protein 2+,What will you do next
C Immediate dialysis
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D Renal transplant
Explanation:
Question: 180
A 24 year female comes for a routine check up.Her thyroid function test is
as follows. Serum T3 = Normal, T4 = Normal, TSH = 10mU/L. What is the
most likely diagnosis?
A Primary hypothyroidism
B Secondary hypothyroidism
C Subclinical hypothyroidism
Explanation:
Question: 181
A 68 year old man diagnosed as having type 2 diabetes, hypertension,
dyslipidemia, CHF and microalbuminuria. The patient is given
prescriptions for lisinopril, metformin,thiazide and a statin.The patient’s
glucose levels are not fully controlled.He is not willing for any injectable
therapy. What will be next appropriate agent
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A Sulfonylurea
B Pioglitazone
C GLP-1 agonist
D SGLT inhibitors
Explanation:
Question: 182
A 48-year-old man noticed that his shoe and ring size started increasing
over the last 1 to 2 years. On examination BP: 160/100 mm Hg; General
appearance: large nose, lips, and jaw; teeth widely spaced. Thyromegaly
present. Chest-clear, CVS- normal. What is the best initial test?
B GH
C MRI head
Explanation:
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Question: 183
A 22-year old male is admitted with fever and altered consciousness for
two days. Examination reveals nuchal rigidity and diffuse petechial rash
on the trunk and lower extremities. The most likely etiologic agent is:
A Escherichia coli
B Streptococcus pneumoniae
C Neisseria meningitidis
D Haemophilus influenzae
Explanation:
Question: 184
A 44-year-old man presents with involuntary movements of his face,
shoulders, and arms. His father had a similar condition. There is also a
history of mood changes for the past 6 months. On examination, he
appears restless with intermittent slow movements of his hands and face.
He has difficulty performing rapid finger movements, and tone is
decreased in the upper and lower limbs. Which of the following is the
most likely diagnosis?
A Parkinson’s disease
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B Huntington’s chorea
C Amyotrophic lateral
sclerosis
D Sydenham’s chorea
Explanation:
Question: 185
A 45-year-old man presents with weakness and fasciculations in his arms
and legs. His cranial nerves are normal, but there is weakness of his left
handgrip and right leg quadriceps with loss of muscle bulk. There are
obvious fasciculations over the left forearm and right thigh. Tone is
increased in the arms and legs and the reflexes are brisk. There is no
sensory loss. Which of the following is the most likely diagnosis?
A Amyotrophic lateral
sclerosis
B Myotonic muscular
dystrophy
C Tabes dorsalis
D Migraine
Explanation:
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Question: 186
Which one of the following is the minimum spirometry criterion for
diagnosis of bronchial asthma?
A Decrease in FEV1 ≥ 20 %
after 6 minutes of exercise
B Increase in FEV1 ≥ 12 %
following administration of
inhaled bronchodilators
Explanation:
Question: 187
A 50-year-old woman presented with pain in her hands for the past year.
The pain is worse in the morning, but improves as she starts to move
around over the course of the day over the next 1 to 2 hours. Reports:
ESR: 68 mm/h, CRP: elevated, Anti-CCP: positive. What is the most likely
diagnosis
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A Rheumatoid arthritis
B Pulmonary TB
C SLE
D Sarcoidosis
Explanation:
Question: 188
A 10-year-old child has recurrent symptoms of joint pains and colicky
abdomen pain. Now he developed swelling of face and low urine output
as noticed by his parents. On examination BP-150/90 mmHg, palpable
purpura on the buttocks are present. Lab tests elevated BUN, serum
creatinine and thrombocytosis is observed. Urine tests revealed
microscopic hematuria. Which of the following is the most likely
diagnosis?
A Wegener’s granulomatosis
C Polyarteritis Nodosa
D Juvenile RA
Explanation:
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Question: 189
A 40 year old male patient has macrocytosis on complete blood count. He
can have all the following conditions EXCEPT:
A Liver disease
B Post splenectomy
C Hypothyroidism
D Myelodysplastic syndrome
Explanation:
Question: 190
In HIV infection IRIS (Immune reconstitution inflammatory syndrome)
usually develops when ART is started at what CD4 count
A Less than 50
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Explanation:
Question: 191
In a study dye A is used to measure cardiac output and plasma volume.
The dye is replaced with a new dye which diffuses more rapidly out of the
capillaries. This would affect-
Explanation:
Correct Answer (C) Cardiac output will be normal as the dye moves into the
interstitial space but as the dye moves out of the circulation concentration of the
dye will reduce in circulation so false high plasma volume will be estimated ie.
A= C X V according to principle of volume distribution of body fluids. So, V= A/C
as C decreases A will be falsely high.
Question: 192
True regarding excitation contraction coupling in smooth muscle is –
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A Presence of troponin is
essential
C Phosphorylation of actin is
required for contraction
Explanation:
Correct Answer (D) Explanation- Ca2+ is essential for muscle contraction, and
troponin is absent in smooth muscle also phosphorylation of myosin not actin is
essential for muscle contraction.
Question: 193
A substance is prepared that specifically and completely inhibits glucose
transport in PCT. In healthy volunteer receiving this substance, clearance
of glucose will approximate the clearance of which of the following?
A PAH
B Urea
C Na+
D Inulin
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Explanation:
Question: 194
All of these are actions of atrial natriuretic peptide except:
A Afferent arteriolar
dilatation
C Decreased sodium
absorption in the PCT
D Inhibition of sodium
reabsorption in medullary
collecting duct
Explanation:
Correct Answer (B) Explanation- ANP causes mesangial relaxation and dilatation
of afferent arterioles leading to increased glomerular filtration and sodium
excretion. It also acts on renal tubules to inhibit sodium reabsorption.
Question: 195
Following a sympathectomy, a 66-yearold man experiences orthostatic
hypotension. The explanation for this occurrence is-
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A An exaggerated response
of the renin–angiotensin–
aldosterone system
B A suppressed response of
the renin–angiotensin–
aldosterone system
C An exaggerated response
of the baroreceptor mechanism
D A suppressed response of
the baroreceptor mechanism
Explanation:
Question: 196
This classical X-ray sign is seen in which of the following conditions :
A Anterior Shoulder
Dislocation
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B Posterior Shoulder
Dislocation
C Inferior Shoulder
Dislocation
D Central Shoulder
Dislocation
Explanation:
Question: 197
The most common cause of relapse after successful correction of CTEV is :
A Overcorrection during
Ponseti’s technique
Explanation:
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Question: 198
Most common complication of fracture neck of talus :
C Subtalar arthritis
D Non union
Explanation:
Question: 199
A 12 year old boy has been complaining of pain and swelling in his right
thigh. He has associated fever as well. He was taken to a doctor where
blood markers were done which show raised TLC , ESR and CRP. He is put
on IV antibiotics and NSAID. He responds to the medicines till the time he
takes them but then symptoms occur again when he stops. X-ray was
done which shows laminated periosteal reaction along the diaphysis of
femur. Which of the following will be the most conclusive investigation to
establish the diagnosis ?
A Bone Scan
B MRI
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C Biopsy
D CT scan with 3D
reconstruction
Explanation:
Question: 200
Most common joint involved in Septic Arthritis :
A Knee
B Hip
C Wrist
D Elbow
Explanation:
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