Background on the compounds in the roots of Uvaria chamae

N°) Name of Compound Molecular Molecular XLogP Références

formula weight 3
1 Chalcone C15H12O 208,26 g/mol 3.1
Diuvaretin chalcone form C30H26O6 482.5 g/mol 6.6 (Koudokpon et
Uvaretin C23H22O5 378.4 g/mol 4.9 al., 2018;
Dichamanetin C29H24O6 468.5 g/mol 5.9 Popoola et al.,
Iso-Chamanetin C22H18O5 362.40 g/mol 4.3 2021)
Chamanetin C22H18O5 362.4 g/mol 4.3
Iso-Uvaretin C23H22O5 378.4 g/mol 4.9
Uvangoletin C16H16O4 272.29 g/mol 3.3
2 Dihydrochalcone C15H14O 210,27 g/mol 3.5
3 Pentanoic acid, 4-methyl, methyl ester C7H14O2 130
4 11-Octadecenoic acid, methyl ester C19H36O2 296
5 2-Methyl-Z, Z-3,13-octadecadienol C19H36O 280
6 D-Limonene C10H16 136 3.4
7 Cyclohexene, 1-methyl-5-(1-methylethenyl) C10H16 136
8 p-Mentha-1,8-dien-7-ol C10H16O 152
9 1(3H)-Isobenzofuranone, C10H14O3 182 (Okereke et al.,
 3a,4,5,7atetrahydro-4-hydroxy-3a,7a- 2023)
dimethyl
10 Cis-p-mentha-1(7),8-dien-2-ol C10H16O 152
11 Copaene C15H24 204 4.5
12 Germacrene D C15H24 204 4.7
13 Hexadecanoic acid, methyl ester C17H34O2 270
14 Methyl 10-trans,12-cis-octadecadienoate C19H34O2 294
15 Methyl 9-cis,11-trans-octadecadienoate C19H34O2 294
16 2H-Pyran-2-one, 6-ethyltetrahydro C7H12O2 128
17 Vinyl ethyl sulfoxide C4H8OS 104 0.3
18 Octasiloxane,1,1,3,3,5,5,7,7,9,9,11,11,13,1 C16H48O7Si8 577
3,15,15-hexadecamethyl
19 Ethanone, 2-(2-benzothiazolylthio)-1-(3,5- C14H13N3OS2 303
dimethylpyrazolyl)-
20 Benzyl benzoate C14H12O2 212 4
21 Dimethoxy-p-cymene C12H18O2 194 3.4 (Thomas and
22 T-cadinol C15H26O 222 3.3 Essien, 2020)
23 Methyl thymol C10H14O 150 3.3
24 Cis-bullatencin C37H66O5Na 590 (Fall et al.,
2002)
25 Chamuvarin C23H22O5 378g/mol 4.9 (Kongstad et
 al., 2015;
Okorie, 1977;
Popoola et al.,
2021)
26 Bullatencin C37H66O5 590g/mol 12.2 (Fall et al.,
2002; Popoola
et al., 2021)
27 Squamocin C37H66O7 618g/mol 9.5 (Popoola et al.,
2021)
28 Neoannonin C37H66O6 606g/mol 11.2 (Fall et al.,
2004; Popoola
et al., 2021)
29 Uvaricin I/II C39H68O 649 (Popoola et al.,
2021)
30 Desacetyluvaricin C37H66O6 606 11.2 (Fall et al.,
2006; Popoola
et al., 2021)
31 Chamuvarinin C37H64O6 605 10.5 (Fall et al.,
2004)

Reference
Fall, D., Duval, R.A., Gleye, C., Laurens, A., Hocquemiller, R., 2004. Chamuvarinin, an Acetogenin Bearing
a Tetrahydropyran Ring from the Roots of Uvaria chamae. J. Nat. Prod. 67, 1041–1043.
https://doi.org/10.1021/np030521a
Fall, D., Gleye, C., Franck, X., Laurens, A., Hocquemiller, R., 2002. Cis -Bullatencin, a Linear Acetogenin
from Roots of Uvaria Chamae. Natural Product Letters 16, 315–321.
https://doi.org/10.1080/10575630290026437
Fall, D., Pimentel, L., Champy, P., Gleye, C., Laurens, A., Hocquemiller, R., 2006. A New Adjacent Bis-
Tetrahydrofuran Annonaceous Acetogenin from the Seeds of Uvaria chamae. Planta Med 72, 938–
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Kongstad, K.T., Wubshet, S.G., Kjellerup, L., Winther, A.-M.L., Staerk, D., 2015. Fungal plasma membrane
H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae
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Okorie, D.A., 1977. New benzyldihydrochalcones from Uvaria chamae. Phytochemistry 16, 1591–1594.
https://doi.org/10.1016/0031-9422(77)84030-2
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Fatokun, A.A., 2021. Potent Nrf2-inducing, antioxidant, and anti-inflammatory effects and
identification of constituents validate the anti-cancer use of Uvaria chamae and Olax subscorpioidea.
BMC Complement Med Ther 21, 234. https://doi.org/10.1186/s12906-021-03404-0
Thomas, P.S., Essien, E.E., 2020. Antiglycation, antioxidant, and cytotoxic activities of Uvaria chamae root
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