+U24BM3502-BIOMEDICAL INSTRUMENTATION

OBJECTIVES
 Analyze the problems in measurement equipment
 Design amplifiers for physiological measurement
 Realize safety requirements of biomedical instrumentation
UNIT I-MEDICAL INSTRUMENTATION SYSTEMS &BIOPOTENTIAL
MEASUREMENT
Generalized scheme of medical instrumentation-statistical analysis of measurement data-
problems encountered with measurements from human beings-errors and type of error in
measurement-general constrains in design and regulation of medical devices-Origin of bio
potential and propagation-electrodes-types of electrodes and their equivalent circuits-recording
problems-motion artifacts, measurements with two electrodes.
UNIT II-RECORDING SYSTEMS
Specification and interpretation of ECG,EEG, EMG-recording of ECG ,12 lead system, EMG
10-20 electrode system-transducers:pressure and temperature measurement-bio amplifiers : need,
types and amplification procedure.
UNIT III-MEASUREMENT OF NON ELECTRICAL PARAMETRS
pH,pO2,pCO2 measurement-colorimeter-spectrophotometer-blood gas analyzer-auto analyzer-Ion
Selective Field Effect Transducer(ISFET)-Immunolgically sensitive FET(IMFET)-Blood
pressure measurement-cardiac output measurement-blood cell counter-dilution
method:indicator,thermal and dye dilution.
UNIT IV-SURGICAL AND ASSIST DEVICES
Spirometry- ventillator- arrhythmia monitor- foetal monitor- incubator- pacemaker- defibrillator-
heamodialysis- heartlung machine- lithotripsy- diathermy.
UNIT V PATIENT SAFETY DEVICES
Physiological effects of current- macroshock and microshock- leakage current- isolation of
patient circuits-test equipments for checking safety parameters of biomedical equipment.
TEXTBOOKS
1. R.S KHANPUR,”HAND BOOK OF BIOMEDICAL INSTRUMENTATION”
2. JOHN G WEBSTER,’MEDICAL INSTRUMENTATION, APPLICATION AND DESIGN’
REFERENCE BOOK
1. DR.ARUMUGAM,’BIOMEDICAL INSTRUMENTATION’
COURSE OUTCOMES
CO1: Design medical instruments and identify problems in measurement
CO2: Design bio amplifiers for various physiological recordings
CO3: Illustrate the function of AD and produce solution
CO4: Design biological sensors for measuring non electrical parameter
CO5: Illustrate safety requirements of biomedical instruments

Assignment topics
1. Describe the purpose, usage and calibration of recording system and analyze two types of
error
2. A nurse reports that a colorimeter that was working is giving low transmittance reading for all
blood samples. Which portion of the device would you check first? Justify your answer
3. Calculate the mean arterial pressure whose bp range is 130/85.
4. Interpret the meanings of hyperpolarization, repolarization, depolarization and resting &action
potential.

Project
1. Design an amplifier to replicate patients ECG signal
2. Design a EMI shielding device for patient safety