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Diaz-Gil, Alicia 2018 - Dementia Journal
Diaz-Gil, Alicia 2018 - Dementia Journal
Dementia
0(0) 1–15
Care needs of people ! The Author(s) 2018
Article reuse guidelines:
with dementia in the sagepub.com/journals-permissions
DOI: 10.1177/1471301218809225
peri-operative environment: journals.sagepub.com/home/dem
A systematic review
Sarah Pendlebury
Departments of General (Internal) Medicine and Geratology, NIHR
Biomedical Research Centre, Stroke Prevention Research Unit, Nuffield
Department of Clinical Neurosciences, John Radcliffe Hospital and the
University of Oxford, Oxford, UK
Debra Jackson
Faculty of Health, University of Technology Sydney (UTS), Sydney,
Australia; Oxford Biomedical Research Centre, Oxford Health NHS
Foundation Trust, Oxford, UK
Abstract
The care of people with dementia within the hospital setting is challenging for healthcare pro-
fessionals. Hospital design and services are not optimized for people with dementia, owing to the
lack of preparation of healthcare professionals and the busy environment of the acute hospital.
The peri-operative environment may present particular difficulties but little is known about the
experience and care of people with dementia in this setting. The aim of this review was to
examine the care of surgical patients who have dementia and their family members in peri-
operative environments and describe strategies adopted by healthcare professionals. A system-
atic search of the following databases was completed: BNI, CINAHL, PubMED and PsychINFO in
accordance with PRISMA guidelines. Data were extracted and analysed within a thematic analysis
Corresponding author:
Alicia Diaz-Gil, Faculty of Health and Life Science, Oxford Institute of Nursing and Allied Health Research, Oxford
Brookes University, Headington Campus, Oxford OX3 BP, UK.
Email: a.diaz-gil@brookes.ac.uk
2 Dementia 0(0)
framework as described by Braun and Clarke. Ten papers based on eight studies were included,
five (n ¼ 355,010 participants) containing quantitative data and five reporting qualitative data
(n ¼ 395 participants). People with dementia who go undergo surgery experienced higher
adverse post-operative outcomes such as respiratory problems or urinary tract infections. The
key elements in surgical care for people with dementia included: health assessment throughout
the surgical trajectory (pre-, intra- and post-operative) and the resources used by healthcare
professionals in the peri-operative care. Healthcare professionals reported difficulties in
the completion of health assessments due to the cognitive status of people with dementia and
a lack of skills in dementia management. The use of restraints was still a common practice and a
source of conflict. Dementia-specific training and guidelines focused on the care of surgical
patients who have dementia in peri-operative environments are required to improve care and
post-operative outcomes. More research is required to develop effective interventions
to improve care and decrease the risk of complications for people with dementia in the peri-
operative care environment.
Keywords
dementia, Alzheimer disease, peri-operative care, post-operative care, pre-operative care,
specialties, surgical, procedure, nursing care
Introduction
Dementia is a progressive disease that affects over 46.8 million people worldwide (Prince,
Comas-Herrera, Knapp, Guerchet, & Karagiannidou, 2016). In the UK, it is estimated that
850,000 people are living with dementia, and this is predicted to rise to more than
one million by 2025, and to two million by 2050 (Lewis, Karlsberg Schaffer, Sussex,
O’Neill, & Cockcroft, 2014). The increasing prevalence of dementia impacts on healthcare
services, with one-quarter of hospital beds occupied by people with dementia, whose hos-
pital stay is more than twice as long as other patients with the same condition (Alzheimer’s
Society, 2016).
People with dementia have a higher prevalence of comorbidities and poorer health status
compared to those without dementia (Martin-Garcia, Rodriguez-Blazquez, Martinez-
Lopez, Martinez-Martin, & Forjaz, 2013). Age-associated conditions such as falls and
cataracts are common (Jefferis, Mosimann, & Clarke, 2011) and may require surgical inter-
vention. Indeed, older adults with Alzheimer’s disease are more likely to need surgery fol-
lowing hip fracture (Lai, Chen, Lin, & Liao, 2013). Despite this, there is limited information
on dementia co-morbidity in patients undergoing surgery and with the increasing prevalence
of dementia, it is expected that the number of surgical procedures in this population
will increase.
Hospital environments are not optimized for the care of people with dementia, as the
impersonal and busy nature of hospital wards can be confusing and disorientating (Moyle,
Olorenshaw, Wallis, & Borbasi, 2008). The impact of hospitalisation for people with demen-
tia includes an increase in behavioural and psychological symptoms of dementia (BPSD),
length of stay and poorer outcomes compared to other patients with the same condition
without dementia (Bynum et al., 2004; Dewing and Dijk, 2016; Sampson et al., 2014).
Diaz-Gil et al. 3
Aims
To examine the elements that affect the care of people with dementia undergoing surgery in
peri-operative environments and identify specific care strategies provided by healthcare
professionals for people with dementia and their family members.
Methods
Search strategy
A systematic search for papers published from 1 January 2000 to 31 December 2017 was
completed using the following electronic databases: BNI, CINAHL, PsycINFO and
PubMED. A combination of the search terms was applied: “Alzheimer’s” or “dementia”
combined with “surgical procedure”, “surgery”, “peri-operative care” or “post-operative”.
In addition, reference lists from included papers were hand searched to identify further
literature. Only literature written in English language was included.
The surgical pathway was operationalized through the term peri-operative and defined as
occurring from: pre-operative assessment through surgery and surgical care and up until
three days post-operative. This included the patients’ admission to the anaesthetic room, the
surgical procedure, the post anaesthetic recovery room and the discharge to the surgical
ward or home.
Inclusion and exclusion criteria. The inclusion criteria were studies that focused on any part of
hospital care for people with dementia in peri-operative trajectory. The exclusion criteria
were studies that did not present primary data, were related to non-surgical environments,
opinion articles or systematic reviews.
Data extraction, analysis and synthesis. Data from the studies were extracted to identify themes
and interpret the results. The thematic analysis framework as described by Braun and
Clarke (2006) was adapted and applied to identify the elements of care across the included
studies. The analysis involved a six-phase process: familiarisation with the published mate-
rial, coding, searching for themes, reviewing themes, defining and naming themes and writ-
ing up. Initially, the studies were analysed line by line and codes were assigned to relevant
sentences. The codes were arranged into similar topics to construct sub-themes related to the
elements of care surrounding the peri-operative care of people with dementia. The coding
4 Dementia 0(0)
process was data driven, where codification was performed following an inductive method
and themes were created from the data. Core concepts from the sub-themes were then
organized to construct thematic headings that best represented the data. Initial analysis
was undertaken by the first-named author, with a process of refinement through regular
meetings and collaborations with the full author team.
Quality appraisal
The included papers were evaluated to assess their scientific rigour, credibility and relevance,
using the Critical Appraisal Skills Programme (2015) assessment tools. The papers were
analysed to determine if the aims of the research and the methodology used were congruent,
the findings consistent and ethical requirements satisfied. The tools applied included: the
Cohort Study checklist (Hu, Liao, Chang, Wu, & Chen, 2012; Jensen-Dahm, Palm, Gasse,
Dahl, & Waldemar, 2016; Seitz, Gill, Bell et al., 2014; Seitz, Gill, Gruneir et al., 2014; Tsuda
et al., 2015) and the Qualitative Checklist (Hynninen, Saarnio, & Isola, 2015a, 2015b;
Jefferis, Clarke, Taylor, & Brittain, 2014; Krupic, Eisler, Skoldenberg, & Fatahi, 2016;
Rantala, Kankkunen, Kvist, & Hartikainen, 2014).
Data from all included studies were extracted into an evidence table. The five qualitative
studies (Hynninen et al., 2015a, 2015b; Jefferis et al., 2014; Krupic et al., 2016; Rantala et al.,
2014) were well presented, with a strong justification of the research purpose and ethical
considerations well discussed. However, all the studies were focused on a single setting or a
specific regional area, which restricts its application to other settings. One of the studies had a
small sample size (Hynninen et al., 2015b) due to the inclusion of people with dementia and
relatives. Nevertheless, the study was included since it was the only one which collected
qualitative data directly from people with dementia and their family members, and it included
a statement for reliability and credibility of the study. The five quantitative studies were well
presented; however, one of them did not identify the confounding factors (Tsuda et al., 2015)
while the rest considered the confounding factors during the data analysis.
All the studies were conducted in an ethical way and presented confidentiality statements
for privacy and protection of participants, adhering to the basic principles of respect, benef-
icence and justice.
Findings
From the 1117 studies screened on the initial search, 1072 were excluded on title screening and
45 were assessed with the inclusion and exclusion criteria (see Figure 1). After full-text screen-
ing, 10 papers were identified; however, two of the studies produced two separate publications
with the same data; therefore four articles from two different studies were also included
(Hynninen et al., 2015a, 2015b; Seitz, Gill, Bell et al., 2014; Seitz, Gill, Gruneir et al., 2014).
Studies included
Qualitave: n=5
Quantave: n=5
Figure 1. PRISMA flow chart of included studies related to peri-operative care of people with dementia.
2015a, 2015b; Jefferis et al., 2014; Krupic et al., 2016; Rantala et al., 2014) explored the
participants’ perspective regarding the peri-operative care of people with dementia through
interviews and questionnaires, with a total of 395 participants.
Of the five quantitative studies, three analysed the adverse post-operative outcomes of
people with dementia (Hu et al., 2012; Seitz, Gill, Gruneir et al., 2014; Tsuda et al., 2015);
one examined the post-operative complications of general anaesthesia (GA) versus regional
anaesthesia (RA) for people with dementia (Seitz, Gill, Bell et al., 2014) and one explored
the pain management of hip-fracture patients with and without dementia (Jensen-Dahm
et al., 2016). Out of the five qualitative studies, two explored the perspectives of nurses
(Krupic et al., 2016; Rantala et al., 2014); one examined the perspective of surgeons
(Jefferis et al., 2014); one analysed the points of view from both nurses and physicians
(Hynninen et al., 2015a) and one from patients and relatives (Hynninen et al., 2015b).
Dementia was associated with significantly prolonged hospitalisation and increased risk
of death (Hu et al., 2012; Seitz, Gill, Gruneir et al., 2014; Tsuda et al., 2015). Overall,
results showed that surgical patients who have dementia encountered significantly higher
post-operative complications and required more medical resources than patients without
dementia (Hu et al., 2012; Seitz, Gill, Gruneir et al., 2014; Tsuda et al., 2015). The preva-
lence of post-operative complications was 42.7% in patients with a diagnosis of dementia
6 Dementia 0(0)
Hu et al. (2012) – – – – –
Tsuda – – – – – –
et al. (2015)
Seitz, Gill, Bell – – – – – –
et al. (2014)
Seitz, Gill, – – – – – –
Gruneir
et al. (2014)
Jensen-Dahm – – – – –
et al. (2016)
Rantala – – –
et al. (2014)
Krupic –
et al. (2016)
Jefferis – – – – –
et al. (2014)
Hynninen – –
et al. (2015a)
Hynninen – –
et al. (2015b)
compared to 22.8% in patients without dementia (Hu et al., 2012). The most common
complications after surgery for people with dementia were surgical site infection, urinary
tract infection and respiratory complications (Hu et al., 2012; Tsuda et al., 2015). People
with dementia also had a higher risk of developing other medical complications such as
acute myocardial infarction, acute renal failure, pneumonia, septicaemia, deep wound infec-
tion, pulmonary embolism, post-operative bleeding and stroke (Hu et al., 2012). The reasons
why people with dementia undergoing surgery encountered more post-operative complica-
tions is unclear and likely to be multifactorial (Hu et al., 2012; Tsuda et al., 2015).
From the thematic analysis of peri-operative care for people with dementia, two main
themes of care were identified: peri-operative health assessment at all stages of the peri-
operative trajectory and the specific care strategies implemented by healthcare professionals,
including environmental resources, restraints, family members, and protocols and guidelines
(see Table 1).
professionals often reported frustration when assessing the physical health of people with
dementia due to the lack of effective communication (Hynninen et al., 2015b; Krupic et al.,
2016). These difficulties occurred across the pre-operative, intra-operative and post-
operative periods, and were associated with under-detecting post-operative complications
(Hu et al., 2012; Hynninen et al., 2015a; Rantala et al., 2014). A lack of effective assessments
of people with dementia throughout the surgical trajectory affected identification of pain,
discomfort and other peri-operative complications (Table 2) (Hynninen et al., 2015a, 2015b;
Rantala et al., 2014).
Pre-operative assessment
The importance of developing and establishing effective communication between patients and
healthcare professionals was highlighted (Jefferis et al., 2014; Krupic et al., 2016). An efficient
pre-operative assessment was recognized as an essential pre-requisite for surgery, but when the
pre-operative assessment was completed under time pressures, understanding of the patient
and their physical and psychological condition was not optimal (Jefferis et al., 2014; Krupic
et al., 2016). In the presence of time pressures, physicians based their decisions on their
instincts and experience rather than formal measures, and often the fact that the person
had dementia went unrecognized, creating highly distressing and potentially dangerous sit-
uations for patients and healthcare professionals (Jefferis et al., 2014). When identifying
dementia, surgeons reported changing their anaesthetic plan after a pre-operative assessment
to support the patient’s individual needs (Jefferis et al., 2014; Hynninen et al., 2015a).
Intra-operative assessment
Two of the studies explored the use of the different types of anaesthesia in people with
dementia (Jefferis et al., 2014; Seitz, Gill, Bell et al., 2014). Three different methods were
analysed: GA, RA and local anaesthesia (LA). Both GA and RA had similar rates of post-
operative complications and mortality for patients with and without dementia undergoing
hip surgery, with no significant evidence on which type of anaesthesia was safer for people
with dementia (Seitz, Gill, Bell et al., 2014). LA is widely used in procedures such as cataract
surgery, but this practice was often reconsidered if the patient had a diagnosis of dementia
and had difficulties communicating and adhering to instructions (Jefferis et al., 2014).
Ophthalmic surgeons performing cataract surgery on people with dementia sometimes
chose to operate on the patient whilst they were awake using LA, and avoided GA because
of deterioration in cognition of the patient (Jefferis et al., 2014). In contrast, other surgeons
were concerned that the patient would become distressed during the procedure if they used
LA, leading to potentially serious situation, which was more of a concern than that of the
associated risks of a GA (Jefferis et al., 2014). For that reason, the use of pre- and intra-
operative medication in the form of sedatives or anxiolytics was considered in procedures
8 Dementia 0(0)
under LA or RA to prevent patients from feeling confused and becoming agitated during
the procedure (Jefferis et al., 2014; Krupic et al., 2016).
Post-operative assessment
The experiences and perspectives of healthcare professionals caring for people with demen-
tia in surgical wards were explored and found registered nurses often felt that they lacked
the skills to complete an appropriate post-operative assessment for people with dementia
(Hynninen et al., 2015a). Physicians reported having received some basic training on demen-
tia and had developed their skills whilst working in primary care, but registered nurses
stated that basic knowledge about dementia was not included in their undergraduate edu-
cation and that they required additional training (Hynninen et al., 2015a; Krupic
et al., 2016).
One of the challenges that healthcare professionals encountered was the early recognition
of post-operative complications (Hu et al., 2012; Hynninen et al., 2015a; Rantala et al.,
2014). Challenges were associated with the busy character of hospital wards, the time
required to effectively assess and observe patients who had dementia, and a focus on task
delivery such as medication administration or wound care, rather than on effective obser-
vation to detect significant changes (Hynninen et al., 2015a, 2015b; Krupic et al., 2016;
Rantala et al., 2014). Registered nurses also reported problems identifying post-operative
complications owing to having insufficient knowledge on BPSD that might affect commu-
nication and assessment (Hynninen et al., 2015a; Krupic et al., 2016; Rantala et al., 2014).
Registered nurses felt they lacked competence in managing BPSD, especially confusion,
aggression or anxiety, despite dedicating more time to patients with a diagnosis of dementia
to establish effective communication and deliver care (Hynninen et al., 2015a; Rantala
et al., 2014).
Post-operative pain is associated with post-operative complications including prolonged
hospital stay, delay in mobility and extended rehabilitation (Jensen-Dahm et al., 2016).
Jensen-Dahm et al. (2016) explored the administration of post-operative pain treatment
for hip-fracture patients with and without dementia and found prescription of pain medi-
cation was equal for both groups. However, although both groups were likely to receive
some kind of analgesia, the total dose of opioids and paracetamol over the first 2 to 3 days
post-operative was lower for people with dementia. This study also found that older patients
who had dementia were more likely to receive this medication in a pro re nata (PRN) basis
rather than fixed and programmed doses. Effective use of PRN medication requires nurses
to recognize patients are in pain. However, registered nurses frequently experienced diffi-
culties in assessing pain, due to communication problems associated with cognitive decline
(Rantala et al., 2014); therefore, patients who are unable to verbally report pain could
demonstrate behavioural changes such as agitation, which may not be recognized as
being associated with pain (Krupic et al., 2016; Rantala et al., 2014).
the use of guidelines, training and support programmes for staff (Hynninen et al., 2015a,
2015b; Jefferis et al., 2014; Krupic et al., 2016; Rantala et al., 2014) (see Table 3).
Environmental resources
Providing a positive atmosphere was considered important to facilitate patients’ engagement
in the care process (Hynninen et al., 2015b). Maintaining a calm environment, for example,
by limiting the personnel around the patient, keeping eye contact during communication or
using an appropriate tone was observed to improve recovery, while stress and restlessness
caused by staff and other patients impacted negatively on recuperation from surgery
(Hynninen et al., 2015a; Krupic et al., 2016).
Creating a familiar environment was also found to be beneficial, for example, healthcare
professionals noticed that bringing personal items into the peri-operative setting had a
positive effect and brought comfort to people with dementia (Krupic et al., 2016). For
the LA procedures, surgeons emphasized the importance of supporting the person with
dementia by bringing someone familiar, like a close family member or carer, to the anaes-
thetic room or even the operating theatre (Jefferis et al., 2014). Strategies such as having
supportive nursing staff to provide confidence and reassurance to the person, having direct
physical contact and ensuring patients were in a comfortable position were also important to
create a safe environment (Jefferis et al., 2014; Krupic et al., 2016).
Discussion
Although previous literature reviews have explored the hospital care for people with demen-
tia (Dewing and Dijk, 2016; Di Nino et al., 2010; Digby, Lee, & Williams, 2017), little is
known about how the surgical trajectory affects the patients with a diagnosed dementia,
their family members, and the healthcare professionals looking after them.
Evidence shows that people with dementia are more at risk of adverse post-operative
outcomes (Hu et al., 2012; Seitz, Gill, Gruneir et al., 2014; Tsuda et al., 2015), which
indicates the need for closer post-operative monitoring and attention to the potential sour-
ces of complications in this population. Hu et al. (2012) suggested the revision of post-
operative care procedures for early recognition and active interventions to improve the
quality of post-operative care for people with dementia. There is a National Dementia
Strategy in the UK (Department of Health, 2009) focused on improving the quality of
care in general hospitals; however, it does not include any intervention specific to the
peri-operative environment, leaving a gap in the current practice yet to be explored.
An element of care emerging from this review as key to optimal dementia care is the peri-
operative health assessment. A decline in patients’ cognitive capacities, together with increased
anxiety compromised communication between the person with dementia and healthcare pro-
fessionals. Patients found difficulty in expressing their feelings and nurses felt unable to rec-
ognize pain, discomfort or other clinical problems. Pain management was an important aspect
highlighted by registered nurses since there were no standardized guidelines available for acute
post-operative pain management for people with dementia. In Rantala et al. (2014) study,
registered nurses in Finland found that the existence of guidelines did not mean their imple-
mentation in practice. Therefore, the development and implementation of acute pain-specific
behavioural assessment strategy for people with dementia is needed.
Other findings include the use of restraints by the nursing staff to preserve patient safety,
and although it is a frequent source of distress for the patients and their relatives, staff felt it
necessary to avoid the patient from inadvertently harming themselves. A report on physical
restraint in hospital settings in England (Mind, 2013) reported healthcare professionals used
physical restraint when patients became highly distressed, but very often they were used
before considering other options. The National Institute for Health and Care Excellence
published a guideline in 2015 about violence and aggression management, which includes
short-term management in health and community settings (NICE, 2015). Adapting the
information available for the use in peri-operative environments could be helpful and give
healthcare professionals specific guidance at the different stages of the surgical trajectory.
There was a general concern about the lack of education on dementia, especially for
nursing staff. While doctors reported receiving some education during their training, regis-
tered nurses felt that they did not have a comprehensive understanding of dementia and
often experienced feelings of frustration related to not being able to deliver appropriate care.
Healthcare professionals in general expected more support in order to deliver quality care
and manage the workload; with more effort needed to create standardized guidelines and
dementia-focused training to enhance care in peri-operative environments. The Dementia
Core Skills Education and Training Framework (Skills for Health, Health Education
England, & Skills for Care, 2015) provides education and training for the health and
care workforce in the UK and their resources are available online. However, further dis-
semination for all healthcare professionals in peri-operative environments is needed so more
staff are able to access and obtain benefit from these (and similar) programmes.
12 Dementia 0(0)
Conclusion
This literature review provides new insights into the peri-operative care of a person with
dementia and gives an idea of the factors that most influence patients, relatives and healthcare
staff during the surgical trajectory. Although some of the studies reviewed were more focused
on the post-operative phase of the peri-operative care pathway rather than the whole process,
it shows the need for more recognition of the pre- and intra-operative processes and the
special needs of people with dementia in surgical environments. The review also reveals
some gaps in the healthcare practice such as standardized protocols and guidelines for health-
care professionals, especially regarding pain management, cognitive assessment and use of
restraints. More support for nursing staff is needed in order to regulate the workload and
avoid burnout. Lack of general knowledge about dementia itself was an important issue and
most of the studies make emphasis on the need of up-to-date training for all healthcare
professionals. Research needs to aim its attention at developing new strategies for hospital
surgical environments to meet the needs of patients, relatives and healthcare professionals
effectively (Skills for Health, Health Education England, & Skills for Care, 2015).
Funding
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or
publication of this article: Funding for this study was obtained from the NIHR Oxford Biomedical
Research Centre.
Diaz-Gil et al. 13
ORCID iD
Alicia Diaz-Gil http://orcid.org/0000-0001-7439-619X
Joanne Brooke http://orcid.org/0000-0003-0325-2142
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Tsuda, Y., Yasunaga, H., Horiguchi, H., Ogawa, S., Kawano, H., & Tanaka, S. (2015). Association
between dementia and postoperative complications after hip fracture surgery in the elderly:
Analysis of 87,654 patients using a national administrative database. Archives of Orthopaedic and
Trauma Surgery, 135, 1511–1517.
Alicia Diaz-Gil is a qualified nurse working within surgical theatres at Oxford University
Hospitals. She is currently completing her PhD with a focus on exploring and developing the
care and support of people with dementia during their peri-operative trajectory.
Joanne Brooke has been at Oxford Brookes University since 2016. She has recently been
awarded the Winston Churchill Memorial Travel Fellowship, which provided her with the
opportunity to explore the support and care of prisoners in custodial settings in New
Zealand, Australia and America. Brooke is a Reader in Complex Older Persons Care,
with a focus on dementia and delirium across acute and primary care settings.
Olga Kozlowska has been at Oxford Brookes University since 2018. She is a Vice Chancellor
Research Fellow focusing on healthcare service integration and the interplay between
mental and physical health.
Diaz-Gil et al. 15
Sarah Pendlebury trained in Cambridge, Oxford and France before undertaking a DPhil
in MRI studies of stroke recovery at Oxford. She completed her clinical training at
Oxford where she is now a consultant physician and geriatrician in the Biomedical
Research Centre and Senior Clinical Fellow affiliated to the University Department of
Clinical Neurology.
Debra Jackson has been at UTS since 2011. She has recently returned from the UK where
she developed and led the Oxford Institute of Nursing, Midwifery and Allied Health
Research (OxINMAHR). In 2016, Jackson was named as a Principal Fellow, NIHR
Oxford Biomedical Research Centre, awarded in recognition of the quality and volume of
her internationally excellent research, and outstanding and sustained contribution, to trans-
lational clinical research that has improved the lives of NHS patients.
Appendix 䊏.
16
Hu et al. To characterize the general Population-based ret- 207,693 surgical Patients with dementia who underwent surgery
(2012)/Taiwan features of post-operative rospective patients had a significantly higher overall post-operative
adverse outcomes among cohort study 18,923 surgical patients complication rate compared to patients with-
surgical patients with dementia out dementia
with dementia Acute renal failure, pneumonia, septicaemia,
stroke and urinary tract infection are the top
priorities for prevention among surgical
patients with dementia
Tsuda et al. To elucidate the complica- Population-based ret- 87,645 older adults Complications such as infections and respiratory
(2015)/Japan tions that occur after hip rospective with hip fractures complications after hip-fracture surgery were
fracture in patients with cohort study 9,419 patients more common in people with dementia.
and without dementia with dementia Other complications such as stroke or cardiac
events had no relevant difference
Seitz, Gill, Bell To examine the association Population-based ret- 6135 individuals Similar rates of post-operative mortality, specific
et al. between anaesthetic tech- rospective received general medical complications and hospital length of
(2014)/ Canada nique and post-operative cohort study anaesthesia (GA) stay for GA and RA
complications in older and 6135 received RA is associated with better outcomes in general
adults with dementia regional anaesthe- anaesthesia
undergoing hip-frac- sia (RA) No greater risks observed of specific post-oper-
ture surgery ative complications or mortality associated
with GA
Other factors other than anaesthesia technique
are associated with post-operative outcomes
on individuals with dementia
Seitz, Gill, To evaluate the association Population-based ret- 45,602 older adults Compared with those without dementia, individ-
Gruneir et al. between dementia and rospective with hip fractures uals with dementia were less likely to be
(2014)/ Canada post-operative outcomes cohort study 16,657 patients admitted to rehabilitation facilities
of older adults with with dementia Among community-dwelling older adults,
hip fractures. dementia was associated with an increased risk
of long-term care admission
(continued)
Dementia 0(0)
Appendix Continued.
Author/country Aims Methodology Sample size Major findings
Appendix Continued.
Author/country Aims Methodology Sample size Major findings