B.

Sc (H) Microbiology, Sem III

Cell Biology (Question Bank)
Q. 1: Define the following? 3 marks each
(i). Oncogene
(ii) Endocrine signaling
(iii) Sarcoma
(iv) Nucleosome
(v) Nuclear pore complex
(vi) Plasmodesmata
(vii) Phagocytosis
(viii) Signal transduction
(ix) Collagen
(x) Desmosomes
(xi) Mitrochondria
(xii) Lysosomes
(xiii) Selectins
(xiv) Clathrin coated pits
(xv) Tumor suppressor gene
(xvi) Autocrine signaling
(xvii) Lamins
(xviii) Synaptonemal complex
(xix) Uniport
(xx) Lipid rafts
Q2: Write short note on the following? 5 marks each
(i). Metastasis
(ii) Calmodulin
(iii) Apoptosis
(iv) Stem cells
(v) Cell cycle check points
(vi) Golgi complex
(vii) ABC transporter
(viii) Eukaryotic cell wall
(ix) MAP kinase pathway
(x) cAMP pathway
(xi) cGMP pathway

Q3: Differentiate the following? 3 marks each

(i) Tight and Gap junction
(ii) Apoptosis and Necrosis
(iii) Hetero chromatin and Euchromatinn
(iv) Mitosis and Meiosis
(v) Microtubules and Microfilaments
(vi) Extracellular matrix and Cell matrix interaction
(vii) Embryonic and Pluripotent stem cell
(viii) Ion channel and ABC transporter
(ix) Integral and peripheral proteins
(x) Carcinoma nad sarcoma
(xi) Autocrine and endocrine signaling
(xii) G1 and G2 phases of cell cycle
(xiii) Actine filaments and intermediate filaments
(xiv) Adhesion and Gap junction
(xv) Nucleoid and Nucleus
(xvi) Peroxisomes and lysosomes
(xvii) Steroid hormone and Neurotransmitter
 (xviii) Primary and Secondary cell wall
(xix) Uniport and Antiport

Q4: Discuss the role of Bcl-2 in the regulation of Apoptosis 3 marks

Q5: Discuss the mechanism of protein folding and processing in endoplasmic

reticulum? 7 marks

Q6: Discuss the role of angiogenesis inhibitors as anticancer agents? 3 marks

Q7: Describe the events involved in cell undergoing apoptosis with the help of
suitable diagram?

Q8: Discuss the stages involved in the development of cancer? 7 marks

Q9: Discuss the properties of cancer cells ? 7 marks
Q10: Discuss briefly the features of Receptor protein tyrosin kinases? 5 marks
Q11: Discuss briefly the signaling mechanism of G-protein coupled receptors?
5 marks
Q12: Explain the fluid mosaic model of cell membrane using a well labelled
diagram? 5 marks
Q13: Enumerate the steps involved in the production of induced pleuripotent stem
cells 5 marks
Q14: Discuss the major categorioes of the cell surface receptors involved in cell
signaling? 5 marks
Q15: Describe the molecular organization of chromatin? 3 marks
Q16: Describe the mechanism of eukaryotic cell cycle regulation? 5 marks
Q17; Discuss the phases involved in the eukaryotic cell cycle with the help of
labelled diagram? 5 marks
Q18: Explain the mechanism of protein glycosylation in golgi apparatus with the
help of diagram? 5 marks
Q19: Write a note on diagnosis and treatment of cancer? 5 marks
Q20: Comment on the structure and function of nucleolus? 5 marks
Q21: Expand the following? 1 marks
each
(i) NLS
(ii) MPF
(iii) LDL
(iv) CFTR
(v) PDGF
(vi) VEGF
(vii) GPCR
(viii) IAP
(ix) ECM
(x) NGF
(xi) CRE
(xii) GABA
(xiii) SRP
Q22: Write the contribution of the following scientists? 2 marks
each
(i) GEORGE PALADE
(ii) SHINYA YAMANAKA
(iii) SIR PAUL NURSE
(iv) ROBERT HORVITZ
(v) IAN WILMUT
(vi) ALFRED KNUDSON