Kingdom of Saudi Arabia

Taibah University – Madinah

College of Applied Medical Sciences
Department of Clinical Laboratory Sciences

Student : Ahmad Khalaf Alsaedi

Student number : 3701447
Supervisor : Ahmad Mohamed
clinical practice 2
MLT 411
 ANNALS OF GLOBAL HEALTH

Paper Title: Prevalence of Prediabetes, Diabetes and Its Predictors among Females in

Alkharj, Saudi Arabia: A Cross-Sectional Study .

Authors : Khaled K. Aldossari, Sameer Al-Ghamdi, Mohammed Ali Batais, Sundas Javad, Shanila
Nooruddin, Nida Zahid, Hira Abdul Razzak, Ashraf El-Metwally, Jamaan M. Al-Zahrani , Abdulrahman
Aldiab.

Hypothesis: Prediabetes, Diabetes and Its Predictors are highly increase over years
in Saudi Arabia .

Aim : The aim of the study is to check the prediabetes and diabetes prevalence , with its
associated risk factors , between young females.

Introduction : Metabolic condition called Diabetes, that is described in "high blood

glucose/sugar levels" the outcome at extreme and insulin worsening resistance . The majority
widely recognized sorts of diabetes incorporate diabetes mellitus Type 1 , diabetes mellitus
Type 2, and gestational diabetes. in any case, presently borderline HbA1c levels are likewise
a significant marker of prediabetes . However, explicit instruments prompting diabetes are
not known . Prediabetes is likewise alluded to as transitional hyperglycemia or borderline
diabetes. Screening examination includes, however isn't constrained to, "easygoing plasma
glucose level, OGTT (oral glucose tolerance test) , FPG (fasting plasma glucose) .The
disorder happens when unequipped for delivering a satisfactory measure the insulin that
discarding blood glucose by pancreatic beta cells, or a human body is unequipped for
utilizing insulin alright for diminishing the glucose levels in blood , or failing to release
enough insulin by pancreatic beta cells. Furthermore, one of the critical resistance of insulin
determinant is obesity , adjusting the hereditary parts of resistance to insulin by adiposity, in
this manner adding to the Type 2 diabetes heterogeneity. In obesity there is increasing in the
demands of insulin , because of beta cell hyper function can bring about depleting the beta
cells, bringing about their inability to perform their function. Middle Eastern nations have an
explicitly high commonness of the two disorders of diabetes and mellitus prediabetes . The
predominance of diabetes in the Saudi populace was 14.4% (females: 13.8%). Of this
number, 33.7% were obese (females: 39.5%) and 68.2% were overweight (females 69.2%)
all this according to the WHO country profile in 2016. A state often perceives the effects of
this emerging public health concern that determined by current epidemiological research
studies in Saudi Arabia. This sort of proof is significant for planning of intervention. This
present examination, hence, expects investigation of the commonness of diabetes and
prediabetes between populace female in Al-Kharj city , methodologies can be created in
early intercession for forestall improvement of diabetes and prediabetes and to and its related
inconveniences.
 ANNALS OF GLOBAL HEALTH
Results: The total of 641 individuals they were participate in this study. The Diabetics are 25
(3.7%), 121 of them are prediabetics (18.8%) , and the nondiabetics are 495 (77.4%). The HbA1c
mean was 5.44 (SD 0.72, territory 2.3–12.7). Around 619 individual's levels of HbA1c under 6.5% ,
3 individuals had a levels of HbA1c above 10%. HbA1c mean levels were significantly higher
between females had diabetes (7.72 SD 2.12) while prediabetics are (5.87 SD 0.17) and
individuals with nondiabetics (5.23 SD 0.32) . The mean of age of individuals in the study was
23.36 (SD 6.5 ) , and range from 18 to 60 years . diabetes People had a higher critical mean in age
(34.5 SD 10.6) when contrasted with people of prediabetes (26.4 SD 8.6) and nondiabetics (22.08,
SD = 4.58) . Between prediabetic individuals , 18 to 24 years were about 61.7%, while 25 to 44 years
were 33.3% of individuals . 25 to 44 years were a higher proportion of diabetics (50%) , while 18 to
24 years were only 29.2%. 45 to 60 years were 46.2% and 38.5% about prediabetics and diabetics,
respectively.

Consolation : The Study shows that diabetes and prediabetes prevalence between Al -Kharj
females was from 3.8% and 18.8%, individually. higher mean BMI and midsection periphery found
in diabetic and prediabetic female individuals, were more established in age, smoked when
contrasted with nondiabetics , and were married .