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Code : 201061N

2nd Professional MBBS Exam., 2023

( New Course )

PHARMACOLOGY

Paper--I
Time : 3 hours Full Marks : 100

Instructions :ih sak Drll

(i) The marks are indicated in the right-hand margin.
(i) Attempt ALL questions.

1. Choose the Correct answer of the

following : 2x5=10

(a) Which one of the following

aasg antimicrobials is safe to prescribe
during pregnancy?

(W,Ampicillin
(i) Tetracycline
clineoudl
(ti) Gentamicin
(iv) Doxycyclinesdstacbr

24AK/589 (Turn Over )

 2 ) s TOso

(D) Which one of the following drugs is

680s used to treat status eplepticus?as
() Sodium valproate
(ü) Ethosuximide
fii) Carbamazepine

(iu) Lorazepam

(c) Which one of the following vitamnins is

used to reduce the adverse drug effects
(side effects) of methotrexate?
() Vitamin A
(ii) Vitamin B

(iüi) Vitamin Ciooi00

(iv) Vitamin D

(d) Which one of the following analgesic

agents possesses least anti-inflam
matory effect?

(i) Diclofenac sodium

(i) Ibuprofen anilsoT
(ii) Paracetamolicesnof
(iv) Indomethacin

24AK/589 (Continued )
 (3 )

(e) Lignocaine produces local anesthesia

by prolonging the inactivated state of
which one of the following ionic
20 J1 channels? ai
(). Potassium channels
(ü) Calcium channels c TOde st

(ii), Sodium channelsfilas (

(iv) Magnesium rchannels c101 (d

2. Write an essay on alpha blockers agents.

Write the detailed pharmacological aspects
of alfuzosin mentioning indications, side
ao effects, precautions, drug interactions and
contraindications. 10

3. Write short notes on the following : 5x4-20

(a) Routes of drug administration

(b) First-order kinetics
(c) Drugs used in treatment of
hypertension
(d) Vitamin D

4. Explain the following statements

mentioning proper scientific basis : 5x3=15
(a) Propranolol is used in treatment of
hypertension.

24AK/589 oo 6a(Tum Over )

 (4 )
(b) Oral contraceptive failure may occur in
females taking phenobarbitone.
(c) Prazosin is used in management of
benign prostatic hypertrophy.
5. Write short notes on the following: 5x4=20
(a) Penicillin
(b) Proton pump inhibitors
(c) Management of rheumatoid arthritis
(d) Management of open-angle glaucoma

6. Write short notes on the following : 5x5-25

(a) Intravenous route of drug
administration

(b) Dopaminers ausb le

(c) Adverse drug reactions
(a) Branches of pharmacology
(e) Teratogenic effects of drug

** *

24AK 2390/589 Code : 201061N