SANTANDER UNIVERSITY

FACULTY OF EXACT, NATURAL AND AGRICULTURAL

SCIENCES
BIOCHEMISTRY I

WORKSHOP REGULATION OF
BLOOD GLUCOSE CONCENTRATION

Answer each of the following questions related to the importance of blood glucose
determination and its relationship with different clinical disorders when carbohydrate
metabolism is altered.
De acuerdo a lo anterior, debe consultar bibliografía, y adicional a ello mirar los siguientes videos
que serán de utilidad.
https://www.youtube.com/watch?v=HJGjNTJgf48
https://www.youtube.com/watch?v=cJTnSD2t4Fg
https://www.youtube.com/watch?v=XfyGv-xwjlI

1. Briefly explain how the process of digestion and absorption of carbohydrates in

the body is carried out.

2. ¿Cuáles son las diferentes rutas o vías que sigue la glucosa en el organismo, una vez ha
sido absorbida a nivel intestinal?

3. What hormones are regulating the concentration of glucose in the blood? Explain its
mechanism of action.

4. Qué proceso se ve estimulado cuando el organismo se somete a ayunos cortos y

ayunos prolongados

5. What tests allow to evaluate the glycemic state of a person.

6. ¿Si un paciente presenta hiperglicemia, esto indica que tiene diabetes?

7. What are the types of diabetes there are?

8. About Glycosylated Hemoglobin:

a. What is glycosylated hemoglobin
b. How it is performed.
c. How useful is it in the clinical laboratory?
d. What are the reference values in:
✓ A healthy adult person
✓ A decompensated diabetic patient
✓ A decompensated diabetic patient

9. What is meant by renal threshold for glucose?

10. What is the renal threshold for glucose?

11. Acerca de la glucosuria:

a. ¿Qué causas pueden generar glucosuria en una persona?
b. ¿La presencia de glucosa en la orina implica siempre diabetes? Justificar
su respuesta.

12. What methods are used in the laboratory for the determination of Glycemia
and glycosuria, respectively. The two methods are equally specific. Justify your
answer.

13. Defina:
a. Alteración de la glucosa en ayunas (AGA)
b. Tolerancia alterada a la glucosa o Intolerancia a los carbohidratos (IHC)

14. According to the American Diabetes Association, what parameters have been
established to diagnose Diabetes, through the analyzes carried out in the laboratory.

15. What is meant by peripheral insulin resistance and what effects it generates in the
organism?

16. Clasificar los siguientes trastornos clínicos y/o enfermedades, de acuerdo a si se

caracterizan por presentar hiperglicemia o hipoglicemia:
a. Pancreatitis
b. Respuesta al estrés
c. Enfermedad de Addison
d. Insulinoma
e. Síndrome de Cushing
f. Glucagonoma