CILIARY BODY The Ciliary Body which is triangular in cross section bridges the anterior and posterior segmen Iris and ciliary body CILIARY BODY IS THE ANTERIOR PARTS OF UVEAL TRACT The Uveal Tract consists of : Iris ( Red ) Ciliary Body (Green) Choroid ( Blue ) IRIS Highly pigmented tissue Regulate the amount of light that reaches the retina by changing pupillary diameter responses to light and spesific pharmacologic stimuli Dilator muscle Sphincter muscle CILIARY BODY
Produces and regulates Aqueous Humor
and thus directly influences the ionic environment and methabolism of lens, cornea and trabecular meshwork Main pharmacologic target in gloucoma treatment PROTEIN TYPES EXPRESSED IN HUMAN CILLIARY BODY 37 % unidentified Functions of major group of expressed genes include : Protein Synthesis ( 20% ) Energy supply and biosynthesis ( 12%) Contractility and cytoskleton structure ( 6%) Cellular signaling & cell cycle regulation (7%) Nerve cell – related task (2%) IRIS-CILIARY BODY SMOOTH MUSCLE
Derived from neuroectoderm
The biochemistry of the smooth muscle of the iris includes Contraction – relaxation Receptors Characterization Second messenger formation and regulation Protein phosphorylation Phospholipid metabolism Arachidonic acid (AA ) release and eicosanoid biosynthesis IRIS MUSCLE LAYER DERIVED FROM NEUROECTODERM Dilator Muscle : response to sympathetic α, Adrenergic stimulation Sphincter muscle : receive its primary innervation from para symphathetic nerve fibers that originate in CN III Nucleus CILIARY BODY SMOOTH MUSCLE
Download Effects Of Brain Derived Mitochondria On The Function Of Neuron And Vascular Endothelial Cell After Traumatic Brain Injury Baoliang Zhang Yalong Gao Qifeng Li Dongdong Sun Xinlong Dong Xiao full chapter