DRUG STUDY

NAME OF MECHANISM INDICATION CONTRAINDIC SIDE EFFECTS NURSING

DRUG OF ACTION ATION CONSIDERATION
Generic Paracetamol  Fever  Hypersensitivity CNS: Headache. 1. Obtain culture and
Name: exhibits analgesic  Mild to  Severe hepatic Psychiatric: Insomnia. sensitivity test results,
Paracetam action by moderate pain impairment or GI: Nausea, vomiting, 2. Monitor vital signs
ol peripheral active liver constipation. closely.
blockage of pain disease (IV) Skin: Erythema, flushing, 3. Assess temperature.
Brand impulse pruritus 4. Advise to avoid alcohol
Name: generation. It Other: Thrombocytopenia, use.
Ifimol produces leucopenia, neutropenia,
antipyresis by angioedema, rarely
Chemical inhibiting the hypotension and tachycardia
Class: hypothalamic
Acetamino heat-regulating
phen centre. Its weak
anti-inflammatory
Therapeuti activity is related
c class: to inhibition of
Analgesic; prostaglandin
Antipyreti synthesis in the
c CNS.

Order:
Paracetam
ol 300 mg
IV q4 PRN
ANST
Generic Inhibits To relieve pain,  History of CNS: Dizziness, confusion, 1. Monitor for salicylate
Name: prostaglandin fever, and hypersensitivity drowsiness. toxicity. In adults, a
Aspirin synthesis, acts on inflammation; to salicylates Special Senses: Tinnitus, sensation of fullness in
the hypothalamus Reduction of including hearing loss. the ears, tinnitus, and
Brand heat-regulating risk of death or methyl Hematologic: Thrombocyto decreased or muffled
Name: center, and nonfatal MI in salicylate (oil of penia, hemolytic anemia, hearing are the most
Zorpin interferes with patients with wintergreen) prolonged bleeding time. frequent symptoms
production of history of  sensitivity to GI: Nausea, vomiting, associated with chronic
thromboxane A, a infarction or other NSAIDs diarrhea, salicylate overdose.
Therapeuti substance that unstable angina  history of GI anorexia, heartburn, 2. Discontinue aspirin use
c class: stimulates platelet pectoris ulceration, stomach pains, ulceration, with onset of ringing or
NSAID aggregation. bleeding, or occult bleeding, GI buzzing in the ears,
other problems bleeding. impaired hearing,
Order: Therapeutic Skin: Petechiae, easy dizziness, GI discomfort
ASA 80 Effect: Reduces bruising, rash. or bleeding, and report to
mg/tab OD inflammatory Urogenital: Impaired renal physician.
with meal response, intensity function. 3. Avoid alcohol when
of pain; decreases Body as a taking large doses of
fever; inhibits Whole: Hypersensitivity aspirin.
platelet (urticaria, bronchospasm, 4. Observe and report signs
aggregation anaphylactic shock of bleeding (e.g.,
(laryngeal edema). bleeding gums, bloody or
black stools, cloudy or
bloody urine).

Generic Nitroglycerin To prevent chest  Hypersensitivity CNS: Headache, blurred 1. Take baseline BP and
Name: causes the pain (angina) in  Severe anemia vision, weakness, vertigo, heart rate with patient in
Nitroglyce relaxation of people with a  Hypotension dizziness, faintness. sitting position before
rin vascular smooth certain heart con CV: Postural initiation of treatment
muscles, causing dition hypotension, palpitations with transdermal
Brand arteriolar and GI: Nausea, vomiting, preparations.
Name: venous dilatation. involuntary passing of urine 2. One hour after
Nitro-Dur, It reduces cardiac and feces, abdominal pain, transdermal (ointment or
Transderm preload and dry mouth. unit) medication has been
-Nitro afterload and Hematologic: Methemoglob applied, check BP and
reduces coronary inemia (high doses). pulse again with patient
Chemical artery spasm, Skin: Cutaneous in sitting position. Report
Class: decreasing vasodilation with flushing, measurements to
Nitrates systemic vascular rash, exfoliative dermatitis, physician.
resistance as well contact dermatitis with 3. Assess for and report
Therapeuti as systolic and transdermal patch blurred vision or dry
c class: diastolic blood Body as a Whole: Muscle mouth.
Vasodilato pressure. The twitching, pallor, 4. Assess for and report
rs reduction of perspiration, cold sweat contact dermatitis from
cardiac work by the transdermal patch
Order: nitroglycerin is 5. Remove transdermal unit
Nitroglyce thought to cause or ointment immediately
rin patch 1 the most relief of from skin and notify
patch OD anginal symptoms. physician if faintness,
ACW dizziness, or flushing
occurs following
application.
6. Advise to report any
increase in frequency,
duration, or severity of
anginal attack.
Generic Exerts direct To prevent  History of Hematologic: Spontaneous 1. Monitor vital signs.
Name: effect on the blood clots from hypersensitivity bleeding, transient Report fever, drop in BP,
Heparin cascade of blood forming to heparin thrombocytopenia rapid pulse, and other
coagulation by  active bleeding Endocrine: Osteoporosis, S&S of hemorrhage.
Brand enhancing the  bleeding suppressed renal function, 2. Protect from injury and
Name: inhibitory actions tendencies hyperkalemia notify physician of pink,
Heparodic of antithrombin III (hemophilia, GI: increased AST, ALT. red, dark brown, or
(heparin cofactor) purpura, Skin: Injection site cloudy urine; red or dark
Chemical on several factors thrombocytopeni reactions: pain, brown vomitus; red or
Class: essential to normal a) itchingcyanosis and pains in black stools; bleeding
Glycosami blood clotting,  severe arms or legs (vasospasm), gums or oral mucosa;
noglycan thereby blocking hypertension reversible transient alopecia hematoma, bloody
the conversion of (usually around temporal sputum; chest pain;
Therapeuti prothrombin to area). abdominal or lumbar pain
c class: thrombin and Body as a Whole: Fever, or swelling; pelvic pain;
Anticoagul fibrinogen to chills, pruritus, skin rashes, severe or continuous
ant fibrin. itching and burning headache, faintness, or
sensations of feet, numbness dizziness.
Order: and tingling of hands and 3. Caution patient that
Heparin 1 feet, elevated BP, headache, smoking and alcohol
amp in nasal congestion, consumption may alter
90cc PNSS conjunctivitis, chest pains, response to heparin and
to run bronchospasm are not advised.
for 5-
10gtts/min.

Generic Naturally Control of  systemic fungal  Opportunistic infection, 1. Give daily dose of
Name: occurring severe or infections infection hydrocortisone in
Hydrocorti glucocorticoids incapacitating  hypersensitivity  Leukocytosis morning to mimic normal
sone (hydrocortisone allergic to the drug or  drug hypersensitivity, peak in adrenocortical
and cortisone), conditions any component anaphylactic/anaphylactoi secretion of
Brand which also have intractable to of the d reaction corticosteroids.
Name: salt-retaining adequate trials formulation  steroid withdrawal 2. Be aware that high-dose
Solu-cortef properties, are of conventional such as syndrome therapy shouldn’t be
used as treatment in: Hydrocortisone  metabolic acidosis given for longer than 48
Chemical replacement Acute non- sodium  Na/fluid retention hours.
class: therapy in infectious succinate ,  alkalosis hypokalemic 3. Be alert for depression
Glucocorti adrenocortical laryngeal edema, Monobasic and psychotic episodes.
 impaired glucose
coid deficiency states. atopic sodium 4. Monitor blood pressure,
intolerance
Their synthetic dermatitis, phosphate electrolyte levels, and
Therapeuti analogs are bronchial  increased insulin weight regularly during
anhydrous,
c class: primarily used for asthma, contact requirement, affective, therapy.
Dibasic sodium
Adrenocor their anti- dermatitis, drug psychotic & mental 5. Monitor blood glucose
phosphate dried,
ticoid inflammatory hypersensitivity disorder level in diabetic patients,
10% Sodium
replaceme effects in reactions,  personality change and increase insulin or
hydroxide
nt, anti- disorders of many seasonal or  confusional state oral
inflammat organ systems. perennial  anxiety 6. Avoid withdrawing drug
ory Glucocorticoids allergic rhinitis,  mood swing suddenly after long-term
 cause profound serum sickness,  abnormal behavior therapy because adrenal
Order: and varied urticarial  insomnia crisis can result. Expect
Solu-cortef metabolic effects. transfusion  irritability to reduce dosage
1 vial 30 In addition, they reactions.  increased intracranial gradually and monitor
mins modify the body's pressure response.
before BT immune response  seizure 7. Inform patient that he
to diverse stimuli.  amnesia may bruise easily.
 cognitive disorder,
dizziness
 headache
 cataract
 glaucoma
 vertigo
 thrombosis
 HTN
 hypotension
Generic Binds to a  To treat mild  History of CNS: Aggressiveness, 1. Obtain culture and
Name: ribosomal subunit community- cholestatic agitation, anxiety, sensitivity test results
Azithromy of susceptible acquired jaundice or asthenia, dizziness, fatigue, 2. Monitor liver enzymes
cin bacteria, blocking pneumonia, hepatic headache, closely in patients with
peptide otitis media, dysfunction hyperactivity, malaise, impaired liver function
Brand translocation and pharyngitis, associated with nervousness, and expect to discontinue
Name: inhibiting RNA- tonsillitis, and prior use of paresthesia, seizures, the drug immediately if
Zithromax, dependent protein uncomplicated azithromycin somnolence, syncope, signs and symptoms of
Zmax synthesis. Drug skin and soft-  hypersensitivity vertigo hepatitis occur.
concentrates in tissue to azithromycin, Hematologic: Leukopenia, 3. Assess patient for
Chemical phagocytes, infections erythromycin, neutropenia, bacterial or fungal
class: macrophages, caused by ketolide thrombocytopenia superinfection.
Azalide and fibroblasts, susceptible antibiotics, other CV: Arrhythmias, chest 4. Urge patient to consult
(subclass which release it bacteria macrolide pain, edema, prescriber before taking
of slowly and may  Plays a antibiotics or elevated serum CK level, OTC drugs, including
macrolide) help move it to cardioprotectiv their components hypotension, ventricular antacids. If they’re
 infection sites. e role in early tachycardia prescribed, tell patient to
Therapeuti phase post-MI EENT: Hearing loss, oral take azithromycin 1 hour
c class: through attenu candidiasis, before or 2 to 3 hours
Antibiotic ating perversion or loss of taste or after taking antacids.
inflammation smell, tinnitus, tongue 5. Warn patient that
Order: and enhancing discoloration abdominal pain and
Azithromy cardiac Endocrine: Hyperglycemia loose, watery stools may
cin recovery. GI: Abdominal pain, occur. If diarrhea persists
500mg/ anorexia, cholestatic or becomes severe, urge
10ml OD jaundice, constipation, him to contact prescriber
ANST diarrhea, dyspepsia, and replace fluids.
elevated liver enzymes, 6. Teach patient to watch
flatulence, hepatic for and immediately
necrosis or failure, hepatitis, report signs of
nausea, pancreatitis, superinfection, such as
vomiting white patches in the
GU: Acute renal failure, mouth.
elevated BUN and
serum creatinine levels
SKIN: Erythema, pruritus,
rash, Stevens–
Johnson syndrome, toxic,
urticaria
Other: Allergic reaction,
anaphylaxis,
elevated serum phosphorus
level, hyperkalemia,
infusion-site reaction
(such as pain and redness)
Paracetamol 300 mg IV q4 PRN ANST
QMC
314 Andres Rizal Medicine Ward
AOrdan
Paracetamol 300 mg QMC
Alliah Jubileen L. Ordan
314 Andres
IV q4 Rizal ( )
PRN ANST Medicine Ward
BSN IV – SLSU
AOrdan
Paracetamol 300 mg Nov. 29, 2020
Alliah Jubileen L. Ordan
IV q4 PRN for T > 37.6C BSN IV – SLSU
Nov. 29, 2020
ASA 80 mg/tab OD with meal

QMC
314 Andres Rizal Medicine Ward
AOrdan
ASA 80 mg/tab Alliah Jubileen L. Ordan
OD with meal BSN IV – SLSU
Nov. 29, 2020/ 9AM

Nitroglycerin patch 1 patch OD ACW QMC

Medicine Ward
AOrdan
314 9 Andres Rizal Alliah Jubileen L. Ordan
Nitroglycerin patch 1 patch BSN IV – SLSU
Nov. 29, 2020/9AM
OD ACW

Heparin 1 amp in 90cc PNSS to run for 5-10gtts/min.

QMC
314 Andres Rizal Medicine Ward
Heparin 1 amp AOrdan
Alliah Jubileen L. Ordan
in 90cc PNSS to run for 5- BSN IV – SLSU
10gtts/min. Nov. 29, 2020

Solu-cortef 1 vial 30 mins before BT

QMC
314 Andres Rizal Medicine Ward
AOrdan
Azithromycin 500mg/10ml OD1 ANST
Solu-cortef vial Alliah Jubileen L. Ordan
30 mins before BT BSN IV
QMC – SLSU
Nov. 29, 2020
Medicine Ward
314 AOrdan
Andres Rizal
Alliah Jubileen L. Ordan
Azithromycin 500mg/10ml BSN IV – SLSU
OD ANST ( ) Nov. 29, 2020