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Superseded European Surveillance Veterinary Antimicrobial Consumption Esvac Data Collection Form - en
Superseded European Surveillance Veterinary Antimicrobial Consumption Esvac Data Collection Form - en
Superseded European Surveillance Veterinary Antimicrobial Consumption Esvac Data Collection Form - en
YEAR
Digit code being a unique identifier for each package size, strength and
formulation of the VMP. Because it is a key variable in many databases
it has to be stable over time i.e. so that VMPs no longer available on the
market or that are no longer registered still can be identified to allow for
analysis of historical data
e
FORM Pharmaceutical Form
PRODUCT INFORMATION
s
Bolus (BOLUS), Injection (INJ), Intramammary (INTRAMAM),
r
Intramammary dry cow treatment (INTRAMAM-DC), Oral solution
individual treatment (ORAL SOLU-IND), Oral solution herd treatment
e
(ORAL SOLU-HERD), Oral pasta (ORAL PASTA), Oral powder individual
treatment (ORAL POWD-IND), Oral powder herd treatment (ORAL
POWD-HERD) Premix (PREMIX), Capsules and Tablets etc (TABL),
Intrauterine preparation (INTRAUT)
PACKSIZE
u
Content Quantity in Package: Pack size (numerical only)
p
E.g.: 100 for 100 tablets or 100 intramammaries; 10 for 10 ml injection;
S
Package of 2 kg premix: 2; Box of 10 blisters of 30 tablets: 300; Box of
12 injectors: 12
E.g.: ML, L, G, KG, PIECE (for e.g. tablets, capsules, bolus and
intramammaries)
e
E.g.: IU, IU/G, IU/ML, IU/PIECE, G, G/KG, G/L, MG, MG/ML, MG/PIECE
r s
In case of a multi-ingredient VMP unit of measurement strength has to
be given for each ingredient in separate lines
e
CONV FACT Conversion Factor
IU When strength is given as IU, IU/ML or IU/PIECE
p
CONV FACT Conversion Factor Prodrug
PRODR
u
Only when strength is given for the prodrug and not for the active
ingredient (e.g. procaine penicillin that is prodrug for benzylpenicillin)
S
INGR Content of Active Ingredient in Package
CONTENT
In case of multi-ingredient VMP the content in the package has to be
given separately for each ingredient in separate lines
CONT UNIT Unit of Active Ingredient in Package
(G)
S u
To be given in gram (G) for all substances
In case of multi-ingredient VMP the content unit has to be given
separately for each ingredient in separate lines
NUMBER
To identify time period for collected sales data
CHARACTER
e d
For validation purposes CHARACTER
d
To e.g. allow for analysis of use of e.g. longacting preparations and
antimicrobial resistance
e
Important to avoid misinterpretation of pharmaceutical form if given CHARACTER
s
in other language than English
e r
Allows for reporting of data as individual or flock treatment
CHARACTER
CHARACTER
Generally, a classification system is necessary to have common
language when reporting use and analysing data with data on AMR,
e.g. for 3rd and 4th generation cephalosporins
Optional
NUMBER
To calculate weight of active ingredient sold
CHARACTER
Important to avoid misinterpretation of ingredient name if given in
other language than English.
Only in cases when the strength is given in IU, IU/ML or IU/UNIT and
when different salts exists to - allow for conversion to weight of
active ingredient
CHARACTER
NUMBER
d
To allow for calculation of the amount of active ingredient in each
e
package/product product and to validate INGR CONTENT
d
CHARACTER
e
To allow for calculation of the amount of active ingredient in each
s
package/product and to validate INGR CONTENT. If
strenght given for PRODRUG apply this and include the PRODRUG
r
CONV FACT
e
NUMBER
When strength is given as IU, IU/ML or IU/PIECE - to allow for
calculation of weight of active ingredient in package
p
NUMBER
NUMBER
CHARACTER
NUMBER
Please specify:
e
Unlisenced products included (lisenced in other MSs)
e r s
p
If no complete coverage,
were the data extrapolated to obtain 100% coverage?
u
Please specify:
d
Yes/No
Yes/No
de Yes/No
e
Yes
s
No
Partially (give %)
e r %
p
No
Yes
u Data source/provider
You
Others
PRODUCT INFORMATION
COUNTRY YEAR MA ID NAME FORM PACKSIZE
e d
Page 13_x000D_ Classified as internal/staff contractors by the European Medicines Agency
#
d
e d
e d
Data Collection Form
e r s
u p
S
Page 14_x000D_ Classified as internal/staff contractors by the European Medicines Agency
#
Data Collection Form
INGREDIENT 1
PACKSIZEU ATCVET SPECIES NO SOLD INGR SALT PRODRUG STRENGTH STRENGHTU CONV FACT IU
EDIENT 1 INGRED
CONV FACT PRODR INGR CONTENT CONTENT UNIT TONS SOLD INGR SALT PRODRUG STRENGTH
G 0
INGREDIENT 2
STRENGHTU CONV FACT IU CONV FACT PRODR INGR CONTENT CONTENT UNIT TONS SOLD INGR SALT
G 0
INGREDIENT 3
PRODRUG STRENGTH STRENGHTU CONV FACT IU CONV FACT PRODR INGR CONTENT CONTENT UNIT TONS SOLD
G 0
INGREDIENT 4
INGR SALT PRODRUG STRENGTH STRENGHTU CONV FACT IU CONV FACT PRODR INGR CONTENT
e
Dihydrostreptomycin sulphate 820
Erythromycin 920
d
Gentamicin 620
e
Kanamycin sulphate 796
Neomycin sulphate 755
s
Neomycin B sulfate (Framycetin) 670
r
Paromomycin* 675
e
Polymyxin B sulphate 8403
Procaine penicilline (benzylpenicillin)*** 1667
p
Spiramycin 3200
Streptomycin 785
u
Tobramycin 875
Tylosin 1000
S
Sources
WHO standards http://crs.pheur.org/db/4DCGI/search?vSelectName=4
*WHO Pharmacopoeia http://apps.who.int/phint/en/p/docf/
**WHO International Biological Reference Preparations http://www.who.int/bloodproducts/catalogue/AntiJan10
***Martindale http://www.medicinescomplete.com/mc/martindale/curr
d
0.000079
e
0.001220
0.001087
d
0.001613
e
0.001256
0.001325
0.001492
0.001481
0.000119
0.000600
0.000313
0.001274
0.001143
0.001000
GI/search?vSelectName=4&vContains=1&vtUserName=ISA&OK=Search
Monographs/Pharmaceutical substances
ducts/catalogue/AntiJan10.pdf
ete.com/mc/martindale/current/141-b.htm?q=procain%20penicillin&t=search&ss=text&p=2#_hit
e
Oxacilline benzathine 0.69
Penethamate hydriodide 0.63
d
Procaine penicillin 0.61
e r s e
S u
Calculation of the conversion factors
Prodrug
Benethamine benzylpenicillin
Benzathine benzylpenicillin
Benzathine phenoxymethylpenicillin
Cloxacillin benzathine
Oxacilline benzathine
Penethamate hydriodide
Procaine penicillin
p MW prodrug
545.701
909.1
941.1
1112.1
641.78
561.5
588.7
Data source: Martindale (2009) (http://www.medicinescomplete.com)
e
QA07AA03
d
QA07AA04
e
QA07AA05
s
QA07AA06
r
QA07AA07
e
QA07AA08
QA07AA09
p
QA07AA10
u
QA07AA11
QA07AA51
S
QA07AA54
QA07AA90
QA07AA91
QA07AA92
QA07AA93
QA07AA99
QA07AB
QA07AB02
QA07AB03
QA07AB04
QA07AB20
QA07AB90
QA07AB92
QA07AB99
QG
QG01
QG01A
QG01AA
QG01AA01
QG01AA02
QG01AA03
QG01AA04
QG01AA05
QG01AA06
QG01AA07
QG01AA08
e
QJ01XQ
d
QJ01XQ01
e
QJ01XQ02
s
QJ01XX
r
QJ01XX01
e
QJ01XX02
QJ01XX03
p
QJ01XX04
QJ01XX05
S
QJ01XX07
QJ01XX08
QJ01XX09
QJ01XX10
QJ01XX55
QJ01XX93
QJ01XX95
QJ51
QJ51A
QJ51AA
QJ51AA03
QJ51AA06
QJ51AA07
QJ51AA53
QJ51B
QJ51BA
QJ51BA01
QJ51BA02
QJ51BA90
QJ51C
QJ51CA
QJ51CA01
QJ51CA51
QJ51CE
QJ51CE01
QJ51CE09
QJ51CE59
QJ51CE90
QJ51CF
QJ51CF01
QJ51CF02
QJ51CF03
QJ51CF04
QJ51CF05
QJ51CR
QJ51CR01
QJ51CR02
QJ51CR50
QJ51D
QJ51DB
QJ51DB01
QJ51DB04
QJ51DB08
d
neomycin
nystatin
e
natamycin
d
streptomycin
e
polymyxin B
s
paromomycin
r
amphotericin B
e
kanamycin
vancomycin
p
colistin
u
rifaximin
neomycin, combinations
S
streptomycin, combinations
dihydrostreptomycin
gentamicin
apramycin
bacitracin
antibiotics, combinations
Sulfonamides
phthalylsulfathiazole
sulfaguanidine
succinylsulfathiazole
sulfonamides, combinations
formosulfathiazole
phthalylsulfathiazole, combinations
combinations
GENITO URINARY SYSTEM AND SEX HORMONES
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Antibiotics
nystatin
natamycin
amphotericin B
candicidin
chloramphenicol
hachimycin
oxytetracycline
carfecillin
d
nifurtoinol
furazolidone
e
Pleuromutilins
d
tiamulin
e
valnemulin
s
Other antibacterials
r
fosfomycin
e
xibornol
clofoctol
p
spectinomycin
methenamine
S
nitroxoline
linezolid
daptomycin
bacitracin
methenamine, combinations
furaltadone
novobiocin
ANTIBACTERIALS FOR INTRAMAMMARY USE
TETRACYCLINES FOR INTRAMAMMARY USE
Tetracyclines
chlortetracycline
oxytetracycline
tetracycline
chlortetracycline, combinations
AMPHENICOLS FOR INTRAMAMMARY USE
Amphenicols
chloramphenicol
thiamphenicol
florfenicol
BETA-LACTAM ANTIBACTERIALS, PENICILLINS, FOR INTRAMAMMARY USE
Pencillins with extended spectrum
ampicillin
ampicillin, combinations
Beta-lactamase sensitive penicillins
benzylpenicillin
procaine benzylpenicillin
procaine benzylpenicillin, combinations
penethamate hydriodide
Beta-lactamase resistant penicillins
dicloxacillin
cloxacillin
meticillin
oxacillin
flucloxacillin
Combinations of pencillins and/or beta-lactamase inhibitors
ampicillin and enzyme inhibitor
amoxicillin and enzyme inhibitor
combinations of penicillins
OTHER BETA-LACTAM ANTIBACTERIALS FOR INTRAMAMMARY USE
First-generation cephalosporins
cefalexin
cefazolin
cefapirin
e
PIECE
r s e d
u p e
S
e
G/L
G/PIECE
d
IU/ML
e
IU/G
IU/PIECE
s
IU/KG
p e r
S u
e
Oral powder individual treatment ORAL POWD-IND
d
Oral powder herd treatment ORAL POWD-HERD
e
Oral solution individual treatment (e.g. mixtures andORAL SOLU-IND
Oral solution herd treatment ORAL SOLU-HERD
s
Oral pasta ORAL PASTA
r
Premix PREMIX
e
Tablets, capsules, boli TABL
p
Intrauterine preparations INTRAUT
Bolus BOLUS
S u
e
QA07AB04
d
QA07AB20
e
QA07AB90
s
QA07AB92
r
QA07AB99
e
QG01AA01
QG01AA02
p
QG01AA03
QG01AA04
u
QG01AA05
S
QG01AA06
QG01AA07
QG01AA08
QG01AA09
QG01AA10
QG01AA11
QG01AA51
QG01AA55
QG01AA90
QG01AA91
QG01AA99
QG01AE01
QG01AE10
QG51AA01
QG51AA02
e
demeclocycline
dibekacin
d
dicloxacillin
e
difloxacin
dihydrostreptomycin
s
dirithromycin
r
doripenem
e
doxycycline
enoxacin
p
enrofloxacin
epicillin
u
ertapenem
S
erythromycin
fleroxacin
flomoxef
florfenicol
flucloxacillin
flumequine
flurithromycin
formosulfathiazole
fosfomycin
framycetin
furaltadone
furazolidone
fusidic acid
e
Turkey TU
d
Pig PIG
Horse HO
e
Rabbits RA
s
Dog DOG
r
Cat CAT
e
Fish FI
Salmon SAL
p
Trout TRO
u
Cod COD
Others ZZ
S
Not given NO
ALL XX
When "ALL" is selected no other species could be specified for the same product.
If you have consumption for a specific species and for the remaining species, use the code of
the species and "ZZ" for others
d
Belgium BE
e
Bulgaria BG
Croatia HR
s
Cyprus CY
r
Czech Republic CZ
e
Denmark DK
Estonia EE
p
Finland FI
u
France FR
Germany DE
S
Greece GR
Hungary HU
Ireland IE
Iceland IS
Italy IT
Latvia LV
Liechtenstein LI
Lithhuania LT
Luxembourg LU
Macedonia, The Former Yugoslav Republic of MK
Malta MT
Netherlands NL
Norway NO
Poland PL
Portugal PT
Romania RO
Slovakia SL
Slovenia SI
Spain ES
Sweden SE
Switzerland CH
Turkey TR
United Kingdom UK