UPSTREAM TC TO site

51 7 31 bindIt ·
i

-
G binds
- relie un

Cast to
Rna
pol-OL G only act
ITFs bind -
> ISTAA
↓ nev
-

allow nucleosome act by add of

to unwind for T

RNASPLICING -
remove I E
out
final product ofME
↑
-

will take place

if in
cast insid
- more
so out
A IT SPUCING of nuclear RNASpre-mRNA =
Depul
transcript
-

diff prod a
or
One Gene : One
Polypeptide
-

· How does Induction Formation occur ?

& Organ
>
-
multicellular org
cell signaling >
-

cell communication
Mechanisms
Autocrine paracin Juxtacine Endocrine
·

L ⑳ !
&
same all
nearby
"
all
et
Y ·
distant all
>
homones to blood
< cutokines & site of
Injury = Fever

·
How Proceed ?
does cell
signaling
D Recognition ligand firet
Greceptor protein
② Transduction act and
magr
③ cell response elicits
respons
Signaling Molecules

HYDROPHOBIC HYDROPULIC

EC Spad EC space

Oreceptaten
-
s
g signalling
- Datas
Maroten
eas Freely
.

auffer
RecepTOR Types

① GPCR
7
-
uns
Mseg 200 protein CGuarine-nucloticbinding
- a

↑
6 Tb
GDP
X
protein)
Gtp to GDP

Ex :
⑪
= t
->

G
Gi Gq
⑮ * d
A Denylate Oyclase Phospholipase ( (in cell memb)
Anamp I ↓
ATp helps IA Phosphatidylinositol-4 ,
5-Bisphosphate
cells
dissociats ↓
eparts ,
~
Wwar as

regulatorySu P KA
differe
-

=
o proteins
can d
in c cast pKC
SM Contrax

& Enzyme Coupub Receptor -

i
J Receptor &
HTMSeg Enzyme DOMAIN
-
protein Kinase . ⑧

* RTKs BIND
Dimeriz
*
Tyr-associated proteins
↓ ↑
Y crossphospho
S.
Pathway + +
& -
⑳
Cyteplate
Tyr
-

Kinde
* Receptor Ser/thr Kinase

o
Typell Tyrel

I I
RIC Rec

③ On channel Receptors

9) Bind + open HW : Research Tournal Connect

#
6) IOns Flow Passively
, ,
Nat ca't
DE
disth
↑ c) charge
C + Response
, d) Cell