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04 - Benzoin Condensation
04 - Benzoin Condensation
04 - Benzoin Condensation
: 011-47623456
The Benzoin Condensation is a coupling reaction between two aldehydes that allows the preparation of
α-hydroxyketones. This method is only suitable for aromatic aldehydes.
Mechanism of Benzoin Condensation
Addition of the cyanide ion to create a cyanohydrin.
(1)
Try Yourself
1. Consider the following reaction
KCN alc.
Ph – CHO Major Product P
CHO
(X) + –CN
Me
O
KCN alc. PCC
Ph – C – H
P Q
(2)
4. Consider the following reaction
CH
KCN alc.
Product (P)
CH 3
P is
O O
(1) (2)
OH
OH OH
(3) (4)
O
O
CHO CHO
KCN
A B
CHO
Product ‘B’ is
(1)
O
O
OH
(2) OH
O
OH
O
(3) O
O
O
O
(4) O
OH
(3)
Answer of Question Based on Beckmann Rearrangement
1. Answer (1)
2. Answer (1)
3. Answer (3)
4. Answer (1)
5. Answer (1)
(4)