BIOCHEMISTRY ‫ طب بشري‬- ‫الدفعة السادسة‬ PAPER 1 - ‫االختبار الشمولي‬

BIOCHEMISTRY PAPER I
Q1:- Choose the correct answer only :-

CARBOHYDRATES:-
1. stage one of glycolysis:-
a) produce 2 ATP.
b) Not produce ATP
c) require one ATP
d) require 2 ATP .

2. diabetes innocence caused by:-

a. defective action of antidiurtic hormone
b. low renal threshold
c. defective insulin action
d. excessive absorption of iron

3. deficiency of aldolase_B enzyme lead to accumulation of: -

a. fructose_1_phosphate
b. glucose_6_phsphate
c. glyceraldehyde_3_phosphate
d. Dihydroxyacetone phosphate

4. regulate Pentose phosphate pathway by:-

(A) Glucose-6-phosphatase
(B) Phosphorylase
(C) Aldolase
(D) Glucose-6-phosphate dehydrogenase

5_ symptoms of hypoglycemia:-
A) tremors . sweating . hunger
B) dehydration
C) Hyperosmolarity.
d) polyuria

6- stimulates of pyruvate kinase.

A) fructos 1.6 bisphosphate .
B) citrate
C) fructos 2.6 bisphosphate.
D) glucokinase

‫ طب بشري – جامعة عمران‬- ‫إعداد اللجنة العلمية للدفعة السادسة‬

BIOCHEMISTRY ‫ طب بشري‬- ‫الدفعة السادسة‬ PAPER 1 - ‫االختبار الشمولي‬

7. Which of the following enzymes is responsible about the conversion of pyruvate to

lactate?
a. lactate reductase
b. pyruvate reductase
c.lactate dehydrogenase
d. pyruvate dehydrogenase

8. the following is known as tricarboxylic acid:-

a. oxaloacetate acid
b. citrate acid
c. malate acid
d. succinate acid

9- Malate - aspartate shuttle operates in......:-

a. liver
b. heart muscle
c. liver and heart muscle
d. non of the above

10. Glycerol _ phosphate shuttle function in....:-

a. lipid oxidation
b. triacylglycerols synthesis
c. anaerobic glycolysis
d. aerobics glycolysis to transfer NADH equalivant result from glycolysis into
mitochondria

11- Fetal genitic deficiency of the ....... lead to Galactosemia:-

a. galactokinase
b. galactose-1-phosphate uridyl transferase
c. UDP-galactose-4-epimerase
d. phosphoglucomutase

12- The Haemolytic anaemia is occur due to deficiency in: -

a. pyruvate kinase
b. Glucokinase
c. PFK-1
d. non of the above

13. Which one of the following is a rate limiting enzyme of glycolysis:-

a. enolase
b. Phsophtriose isomerase
c.glyceraldehyde_3_phosphate dehydrogenase
d. Phosphofrctukinase 1

‫ طب بشري – جامعة عمران‬- ‫إعداد اللجنة العلمية للدفعة السادسة‬

BIOCHEMISTRY ‫ طب بشري‬- ‫الدفعة السادسة‬ PAPER 1 - ‫االختبار الشمولي‬

14.growth hormone actsas :-

a. blocks the insulin action at cell membranes
b. stimulation glucose oxidation
c. stimulation glucose breakdown
d. stimulation glucose to enter inside cells

LIPIDS:-
15. after meal lipogenesis is:-
a) stimulated
b) Inhibited
c) stimulated glycolysis
d) stimulated lipolysis

16.this lipid never oxidized to give energy:-

a. tissue lipid
b. adipose tissue
c. white adipose tissue
d. brown adipose tissue

17. ....... deficiency lead to Gaucher's disease:-

a. lipoprotein lipase
b. Protease
c. glucoserebrosidase
d. HMG reductase

18- it does not contain enzymes for ketolysis and not oxidation them:-
a. liver
b. Brian
c. kidne
d. muscle

19- The fatty Acids Synthesis occur in:-

a. cystol
b. mitochondria
c. Endopalsmic reticulum
d. all the following

20- the organ acts roll both in synthesis and utilization of lipids:-
a. liver
b. kidney
c. lung
d. stomach

‫ طب بشري – جامعة عمران‬- ‫إعداد اللجنة العلمية للدفعة السادسة‬

BIOCHEMISTRY ‫ طب بشري‬- ‫الدفعة السادسة‬ PAPER 1 - ‫االختبار الشمولي‬

21- cholestrol is the precursor in the biosynthetase of , except:-

a. steroid Hormone
b. aldosteron Hormone
c. thyroid hormone
d. bile salts

22- cholesterol is regulated by:-

a. HMG CoA reductase
b. HMG CoA synthetase
c. cholestrol ester
d. thiokinase

23. increased synthesis of cholesterol by:-

a. insulin
b. Glucagon
c. Glucocorticoids
d. all the above

24- lack appropriate lipid absorption called:-

a. obesity
b. steatorrhea
c. metabolic syndrome
d.fatty liver

Q2:- WRITE:-
1- what do you know about familial hypercholesteremia ?
2- how the cholesterol is regulate?
3- what is the malate - aspartate shuttle?

‫ طالب الدفعة السادسة – طب بشري‬:‫تجمٌع‬

‫ موسى عبدهللا الصعر‬:‫مندوب الملتقى‬

ً‫ احمد ٌحٌى الشعب‬:‫مندوب الدفعة‬
‫ مقبل ناصر مارط‬:‫مسؤول اللجنة العلمٌة‬
ً‫ أحمد عروه الذانب‬:‫تنسٌق‬
‫ طب بشري – جامعة عمران‬- ‫إعداد اللجنة العلمية للدفعة السادسة‬