The Role of Microbiota in Gut Homeostasis and Inflammatory Bowel Disease

This comprehensive review paper delves into the intricate relationship between gut microbiota and
inflammatory bowel disease (IBD). It explores how the composition and diversity of microbial
communities in the intestines influence the development and progression of IBD, which includes Crohn's
disease and ulcerative colitis. The paper discusses the mechanisms through which microbiota contribute
to gut homeostasis, such as metabolite production and immune modulation. It also examines factors like
diet, genetics, and environmental influences that can disrupt microbiota balance (dysbiosis) and
exacerbate IBD symptoms. Furthermore, the review highlights emerging therapeutic strategies aimed at
restoring microbial equilibrium to alleviate inflammation and promote gut health.