Professional Documents
Culture Documents
2024 Cuadernillo Ingles 2 Mod 1
2024 Cuadernillo Ingles 2 Mod 1
Proyecto original:
Dr. Efraín Davis
Coordinación:
Mgter. Ana Claudia Saraceni
Equipo:
Lic. Ana María Carrizo
Mgter. Gabriela D’Anunzio
Mgter. Bárbara Konicki
Lic. Mariana Sanjurjo
Content Organization
Section 1
Serendipitous discoveries that changed the world
- Reading
- Vocabulary building
- Grammar stop: Connectors Part 1 (as, therefore, however)
- Check your progress 1
Section 2
- Grammar stop: Passive Voice
- Check your progress 2
- Express yourself: Describing and organizing information
Section 3
Bio Pill: Horace Wells
- Reading
- Question block: Active Voice vs. Passive Voice
- Check your progress 3
- Express yourself: Giving your opinion
Academic Literacy I
- Abstracts: Revision of moves
1
MODULE 2: THE RIGHT PERSON FOR THE RIGHT JOB
Section 1
The personality traits needed to be hired
- Reading
- Vocabulary building
- Lexis and Grammar stop: Describing qualities, abilities, obligations, expectations
and likes and dislikes
- Check your progress 1
- Express yourself
Section 2
- Grammar stop: Connectors Part 2 (also, what’s more, moreover, besides,
although)
- Check your progress 2
Section 3
Bio Pill: Ray Bradbury
- Reading
- Grammar stop: Past Simple revisited, Past Perfect
- Check your progress 3
- Grammar stop: Connectors Part 3 (after, before)
- Check your progress 4
- Question block: Past perfect
- Check your progress 5
Academic Literacy II
- Abstracts: Background and Purpose
Integrated Practice 1
- Practice for First Mid-term Test
2
MODULE 1
SERENDIPITY IN ACTION!
3
SECTION 1
BEFORE READING
a) Look at the title and picture of Module 1 again. Can you guess the meaning
of “Serendipity”?
Serendipity /ˌsɛr(ə)nˈdɪpɪti/
a. the state of being calm, peaceful, and untroubled
b. the feeling of sorrow and compassion caused by the suffering and misfortunes
of others
c. the faculty or phenomenon of finding valuable or beneficial things by chance
b) Have a look at the pictures and complete the table with the name of the
discovery and its discoverer. One has been done for you!
a) b) c)
Discovery Penicillin
Discoverer
c) What do you think the three discoveries above may have in common? Read on
to find out.
……………………………………………………………………………………………………………………………………………………………
WHILE READING
Check if your answers to the previous activity were right or wrong.
“Necessity is the mother of invention,” the English proverb goes. However, from
penicillin and anesthesia to chewing gum, chance played a major role in some of the
world's great inventions. Some things were not searched for, but in the end, they
turned out to be something great. Read on to learn about how these happy accidents
were first discovered!
4
Penicillin
Anesthesia
Chewing Gum
https://www.google.com/url?q=https://www.rd.com/list/10-accidental-discoveries-put-to-good-use/&sa=D&source=docs&ust=1670362023423703&usg=AOv
Vaw1psiDHm1YfeZLXxpVtgU8K
https://www.britannica.com/biography/Horace-Wells
https://www.hbs.edu/leadership/20th-century-leaders/details?profile=thomas_adams_jr#:~:text=Thomas%20Adams%2C%20Jr.,-American%20Chicle%20C
ompany&text=Experimenting%20with%20chicle%20(a%20gum,American%20Chicle%20Company%20in%201899.
5
AFTER READING
Quiz your classmates! Prepare one true or false sentence about each of the
texts above. Then, read them to the rest of the class to check if they
understood the texts. If the sentence is wrong, they must correct it!
1. ……………………………………………………………………………………………………………………………………………………………
2. ……………………………………………………………………………………………………………………………………………………………
3. ……………………………………………………………………………………………………………………………………………………………
VOCABULARY BUILDING
GRAMMAR STOP
Let’s reread the text on the discovery of anesthesia. This time, pay attention to
the words in bold letters. What are they used for?
6
patient groaned, Wells was exposed to ridicule as onlookers concluded that the
patient felt pain. However, he did not give up on his hypothesis and nitrous oxide
became an early form of anesthesia.
CONNECTORS (PART I)
Connectors are used to establish connections between two words, clauses,
sentences, and even paragraphs. They allow you to establish a logical relationship
between ideas -which, in turn, makes your speech more structured and harmonious.
AS - THEREFORE - HOWEVER
Which connector could be used to replace “as” in the sentence below: so, because or
but? What is the function of the connector “as”? What is the other possible
position of the connector in the sentence?
Which connector could be used to replace “therefore” in the sentence below: so,
because or but? What is the function of the connector “therefore”? What changes
do you need to make as regards punctuation?
● A man gashed his leg but did not feel any pain. Therefore, Wells started
using nitrous oxide in painless dental operations.
● ……………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………
Which connector could be used to replace “however” in the sentence below: so,
because or but? What is the function of the connector “however”? What changes
do you need to make as regards punctuation?
● Wells was exposed to ridicule as onlookers concluded that the patient felt
pain. However, he did not give up on his hypothesis and nitrous oxide became
an early form of anesthesia.
● ……………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………
7
Now, look for examples of connectors in the texts about penicillin and chewing gum.
Then, include all the connectors presented in this section in the table of connectors
at the end of the booklet.
b) Complete the text below with the following connectors: however, as,
therefore.
1
………………… chicle was foreseen by industrial developers as an equivalent to rubber, in
1869 Antonio López de Santa Anna, a former president of Mexico, considered it as a
potential means of funding his return to power. 2………………………, he was seized upon the
idea of using chicle in place of rubber in the manufacture of tires.
When Adams was conducting tests of various formulas, he discovered that the
desiccated resin was insoluble in water and extremely plastic. 5……………………… , in an
attempt to salvage his investment, he began selling small portions of flavourless
chicle to drugstores. Adams’ formula was not the first chewing gum patented in the
United States; 6………………………, it became the most popular 7…………………… Adams added
various flavours to his product. Adams’ discovery was patented in 1871.
Natural chicle is made from the coagulated milky latex of the sapodilla tree, a
tropical fruit tree of Central America; 8……………………… , after World War II, chicle
was virtually replaced by various waxes, plastics, and synthetic rubber in chewing
gum manufacture. Artificially sweetened chewing gum found a wide market in the
United States beginning in the late 20th century with a wide variety of flavours;
9
………………………, mint remained the favourite one.
8
c) Paraphrase these sentences by using the appropriate connector: AS,
THEREFORE, HOWEVER. Make any necessary changes.
1. All penicillins work in the same way because the bacterial enzymes responsible
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
3. Penicillin G is still widely used but it isn’t resistant to digestive acids, which
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
replicating and producing cell walls so they do not harm human cells.
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
5. Penicillins do not harm human cells because they fundamentally lack cell walls.
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
and various other infections but they are not effective on viral infections.
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
Adapted for pedagogical purposes from:
https://www.britannica.com/science/penicillin
9
SECTION 2
GRAMMAR STOP
Let’s reread this extract from the text on the discovery of penicillin. This time,
pay attention to the words in bold letters. What are they used for?
When Fleming returned from his vacation, he found the dish was covered with
bacteria except in the area where there was mold. Was the mold preventing
bacteria from proliferating? Yes, it was! And this is how penicillin was discovered
and many infectious diseases could be controlled. Therefore, medicine was
immediately revolutionized. Penicillin is probably the greatest medical
breakthrough of all times.
Have you heard about the terms Active Voice and Passive Voice? Do you know
about their differences? When do you use them? How do you use them?
PASSIVE VOICE
● Most sentences in the language are in the Active Voice, when the subject is the
focus of the action. Example:
We pay attention to the “doer” of the action, and we can answer this question:
“Who does the action?” In the example above, who did the action of discovering?
● However, sometimes we need to change the focus and pay attention to the
“receiver” of the action and the action itself. The object of the sentence
becomes the new subject. This is the Passive Voice.
10
question: Who or what is affected by the action? In the example above, what is
affected by the action of “discovering”?
Important!
The verb “to be” indicates the tense in the Passive Voice. To determine the verb
tense in a Passive Voice sentence we must observe how the verb “to be” is
conjugated. We can also use Passive Voice sentences with Modal Verbs.
Notice!
If you need to include an adverb, it is usually placed between the verb “to be” and
the past participle verb.
Example:
Penicillin was accidentally discovered after a holiday.
1. When we want to emphasize the object or action (and not the “doer” of the
action). Example:
Can you identify other examples of Passive Voice in the text “Serendipitous
discoveries that changed the world”?
11
CHECK YOUR PROGRESS 2
The naturally occurring penicillins, penicillin G and penicillin V, 1use still/are still
used clinically. Because it has poor stability in acid, much of penicillin G is broken
down as it passes through the stomach, so it 2must give/must be given by
3
intramuscular injection, which limits its usefulness but penicillin V typically
gives/is typically given orally as it is more resistant to digestive acids than
penicillin G. Some of the semisynthetic penicillins are also more acid-stable so
they 4may give/may be given as oral medication.
5
All penicillins work/are worked in the same way: the bacterial enzymes
6
responsible for cell wall synthesis in replicating microorganisms inhibit/are
inhibited. Also, other enzymes are activated to break down the protective wall of
the microorganism. What’s more, they are effective only against microorganisms
that are actively replicating and producing cell walls so they 7do not harm/are not
harmed human cells (which fundamentally 8lack/are lacked cell walls).
9
Penicillins use/are used in the treatment of throat infections, meningitis,
syphilis, and various other infections.
Adapted for pedagogical purposes from:
https://www.britannica.com/science/penicillin
12
of flavourless chicle to drugstores. Adams’ formula was not the first chewing gum
patented in the United States but, with the addition of various flavours, it
…………………………3(become) the most popular.
d) Choose the correct information from each column to piece together the
story of each discovery. Then, write a short paragraph about them using
verbs in the active or passive voice and connectors.
Example:
Anesthesia was discovered by dentist Horace Wells in 1844. In its beginnings, nitrous
oxide was strictly used as a party toy as it made people howl like hyenas. However, a
man who took too much of the stuff at a laughing-gas roadshow gashed his leg. The
dentist noticed that the man didn’t feel any pain. Therefore, nitrous oxide became an
early form of anesthesia.
13
Now, it’s your turn! Remember to match the information before you write the
paragraph!
14
1. Saccharin
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
2. The microwave
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
3. Botox
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
4. Brandy
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
15
EXPRESS YOURSELF
Defining a concept
● … can be described as …
● … can be defined as …
● … is used to …
● … deals with …
Describing a process
● … was / were invented / discovered / coined / developed / influenced by
… in …
● First, … For example, … Therefore, … However, …
● Also, … / Then, … For instance, … Finally, …
● In conclusion, … / To sum up, ... as / because …
“We are going to talk about anesthesia. It can be defined as a medical treatment
that prevents patients from feeling pain during surgery.
Anesthesia was discovered by chance back in 1844. When dentist Horace Wells was
participating in a laughing-gas roadshow, he noticed that a man gashed his leg.
However, he didn’t feel any pain. Therefore, Wells concluded that nitrous oxide (or
“laughing gas”) had pain-killing properties and started using it in painless dental
operations. He was allowed to demonstrate the method at the Massachusetts General
Hospital in January 1845, but when the patient groaned, Wells was exposed to
ridicule as onlookers concluded that the patient felt pain. However, he did not give
up on his hypothesis and nitrous oxide became an early form of anesthesia.
To sum up, anesthesia allows people to have procedures that will lead to healthier
and longer lives.”
16
b) Research work!
Note-taking grid
d) Which discovery or breakthrough did you find the most interesting? Use
your notes to justify your choice.
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………………………
17
SECTION 3
BIO PILL
BEFORE READING
Read the title of the text and have a look at the picture below, who are we
going to read about?
……………………………………………………………………………………………………………………………………………………………
WHILE READING
a) The following words and phrases have been extracted from the Bio Pill. What
can we infer about the character’s life ?
b) As you read the text, complete the blanks with the words above.
He left his family and moved to New York City. On January 21, 1848, his 33rd
birthday, Wells was 6____________ for throwing acid at two women while under the
18
influence of chloroform and was taken to the Manhattan House of Detention. He used
chloroform and a razor to take 7 in his cell.
The Parisian Medical Society named him the first to perform operations without pain
8
twelve days before his death. However, Horace Wells . What’s
more, he was recognized for discovering the principle of anesthesia by the American
Dental Society in 1864 and the American Medical Association in 1870. His impact as a
pioneer on modern dentistry is sometimes overlooked because of his tragic end.
AFTER READING
a) Order out these events from the Bio Pill.
Wells continued working with anesthesia with Dr. William Morton to create
ether anesthesia.
As Dr. Wells’ patient at the Massachusetts General Hospital in 1845 was both
obese and alcoholic, his demonstration failed.
Dr. Wells committed suicide.
The American Dental Society recognized Wells for discovering the principle
of anesthesia.
Horace Wells became addicted to chloroform.
Wells was named the first to perform operations without pain by the Parisian
Medical Society.
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
QUESTION BLOCK
a) First, order out the following questions about the section “Bio pill: The
man behind anesthesia”.Then, answer them.
Example:
19
Question: Why do most patients have very limited knowledge about anesthesia?
Answer: Because anesthesiology is still misconceived as a behind the screen
specialty.
1. continue / did / after his failed demonstration / his dental practice / Horace
Wells / ?
Q: ___________________________________________________________
A: ___________________________________________________________
Q: ___________________________________________________________
A: ___________________________________________________________
Q: ___________________________________________________________
A: ___________________________________________________________
Q: ___________________________________________________________
A: ___________________________________________________________
5. __________________________________________________________?
No, nitrous oxide doesn’t work well on people who are obese or drink lots of
alcohol.
6. __________________________________________________________ ?
7. __________________________________________________________?
20
8. __________________________________________________________ ?
Yes, Horace Wells was recognized for discovering the principle of anesthesia by
the American Dental Society in 1864.
c) Finally, complete these charts about question making with some examples
from the two previous tasks. Have a look at the example:
Yes/No
questions ______
Wh-
questions
Yes/No ________
questions
SUBJECT QUESTIONS
ACTIVE VOICE
21
SUBJECT QUESTIONS
PASSIVE VOICE
a)
1. In his career as a dentist, Dr. Horace Wells proposed that his patients have
regular check ups. Also, he was recognized as one of the first proponents of
paediatric dentistry b)because he believed that good oral hygiene needed to begin
early in a person’s life.
a. What………………………………………………………………………………………………………………………?
b. Why………………………………………………………………………………………………………………………?
2. On January 21, 1848, his 33rd birthday, Wells was arrested c)for throwing acid at
d)
two women while under the influence of chloroform and was taken to the
e)
Manhattan House of Detention. He was deeply worried about the consequences of
his arrest on his wife and son. Before taking his own life in his cell, he wrote f)a
letter begging forgiveness from God and his family.
c. Why………………………………………………………………………………………………………………………?
d. Where…………………………………………………………………………………………………………………?
e. ………………………………………………………………………………………………………………………………?
f. ………………………………………………………………………………………………………………………………?
22
g. What ……………………………………………………………………………………………………………………?
h. Why ………………………………………………………………………………………………………………………?
i. ………………………………………………………………………………………………………………………………?
j. Who………………………………………………………………………………………………………………………?
k. ………………………………………………………………………………………………………………………………?
l. ………………………………………………………………………………………………………………………………?
b) Choose the right option. You will integrate tenses and connectors.
Nitrous oxide doesn’t work as well on people who are obese or drink lots of alcohol,
and Dr. Wells’ demonstration patient at the Massachusetts General Hospital in 1845
was both. 1However,/Therefore, this discovery was not made until later and Horace
Wells gave up his dental practice after he 2ridiculed/was ridiculed for his failure.
Wells continued working with anesthesia with Dr. William Morton to create ether
3
anesthesia. However,/Therefore, he received hardly any credit for his work.
4
As/But Horace became increasingly discouraged, he began experimenting with
chloroform in the late 1840s and he eventually became addicted to it.
He left his family and moved to New York City. On January 21, 1848, his 33rd
birthday, Wells was arrested for throwing acid at two women while under the
influence of chloroform and was taken to the Manhattan House of Detention, which
5
knew/was known as “the Tombs.” He used chloroform and a razor to take his own
life in his cell where he 6found/was found the next morning.
Horace Wells 7named/was named the first to perform operations without pain
twelve days before his death by the Parisian Medical Society 8but/however he never
found out. What’s more, he was recognized for discovering the principle of
anesthesia by the American Dental Society in 1864 and the American Medical
Association in 1870. 9Therefore/As his life ended tragically, his impact as a pioneer
on modern dentistry 10sometimes overlooks/is sometimes overlooked.
23
EXPRESS YOURSELF
● I think …
● I suppose ... (tentative)
● I suspect that …
● I’m pretty sure that ... (only with friends)
● I’m fairly certain that …
● It’s my opinion that …
● I’m convinced that … (strong opinion)
● I wonder if … (an open opinion)
Choose ONE topic and write down your opinion in a five-sentence paragraph.
Use expressions of opinion and connectors introduced in this module. Be ready
to share your work with your classmates!
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
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………………………………………………………………………………………………………………………………………………………
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24
TIME FOR FICTION I:
“A SOUND OF THUNDER” BY RAY BRADBURY - PART I
BEFORE READING
Read the title of the story and have a look at the picture. How do you feel
when you hear the sound of thunder? What can you predict about the
atmosphere of the story?
WHILE READING
Read Part I of “A Sound of Thunder” and find out if your feelings and
predictions are represented in the text.
A SOUND OF THUNDER
BY RAY BRADBURY
PART I
The sign on the wall seemed to be moving under a thin film of warm water.
Eckels closed his eyes for a moment and the sign burned in his memory:
TIME SAFARI, INC.
SAFARIS TO ANY YEAR IN THE PAST.
YOU NAME THE ANIMAL.
WE TAKE YOU THERE.
YOU SHOOT IT.
Warm liquid gathered in Eckels' throat. He swallowed and pushed it down. The
muscles around his mouth formed a smile when he put his hand slowly out upon the
air. In that hand he waved a check for ten thousand dollars to the man behind the
desk.
Eckels wasn’t promised to come back alive. In fact, he was guaranteed nothing
but dinosaurs. Immediately, he was introduced to Mr. Travis, his safari leader in
the past.
25
“If he tells you not to shoot, you won’t. If you don’t do as he says, you will have
to pay another ten thousand dollars and face possible government action.”
Eckels looked quickly across the large office. There were hundreds of wires
flashing together, looking like a single mass and making a low continuous sound.
There were metal boxes that produced changing bands of light... now orange, now
silver, now blue. There was a sound like a huge fire burning all of Time, all the years
and all the calendars, all the hours piled high and set on fire. Therefore, he was
breathless and couldn’t believe his eyes.
"A real Time Machine." He shook his head. “Thank God Deutscher doesn’t have
one to go back in time and change the results. Thank God Keith will make a fine
President of the United States."
"Yes," said the man behind the desk. "We're lucky. Deutscher makes a man who
is for war but against everything else; against religion, against helping people, and
against people knowing too much. However, Keith is the president now, so there’s
nothing to worry about except…”
"Shooting my dinosaur!" Eckels finished it for him.
"A Tyrannosaurus Rex. The King of Dinosaurs, the most amazing Monster in
history. Sign this form saying that if anything happens to you, we will not be
responsible. Those dinosaurs are hungry."
Eckels’ face turned red. "Are you trying to scare me?" he said angrily.
"To be honest, yes. We don't want anyone going who'll get scared and do
something silly at the first sign of danger because six safari guides and twelve
hunters were killed last year. We're here to give you the most exciting experience
a real hunter ever asked for: taking you back sixty million years to shoot the
biggest game in all of Time. Your personal check's still there. Tear it up."
Mr. Eckels looked at the check. There was a small movement of his fingers.
"Good luck," the man behind the desk said. "Mr Travis, he's all yours."
26
VOCABULARY BUILDING
Read the extract again and match these words and expressions to their
corresponding definitions:
AFTER READING
a) Re-read the text and order out these ideas on the protagonist as they take
place in the story.
………………………………………………………………………………………………………………………………………………
27
2. What was Eckels promised?
………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………
……………………………………………………………………………………………………………………………………………
6. Why didn’t the company want anyone to get scared and do something silly ?
………………………………………………………………………………………………………………………………………………
EXPRESS YOURSELF
Choose one of the following topics, write down your opinion on it and be ready
to share your viewpoint with the rest of the class.
science.
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
………………………………………………………………………………………………………………………………………………………
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28
ACADEMIC LITERACY I
According to Busch-Lauer (2014), abstracts have turned into one of the most
abstracts are required for graduation works such as B.A., M.A. and PhD theses,
grant proposals, short communications and for specific disciplinary purposes. Their
main function is to give the reader orientation on whether to read the complete
Moreover, abstracts are used to easily store and retrieve information in online
Because an abstract is often reproduced separately from the full paper, it has to
pattern of five moves identified by Swales (1993). These moves constitute the
transitions between the different stages of the abstract and each one has a
length can vary from a phrase to sentences and some moves may be omitted
Gábor L. Lövei. Writing and Publishing Scientific Papers: A primer for the non-English speaker
https://books.openbookpublishers.com/10.11647/obp.0235.08.pdf
29
a) Complete the table below with the names of the abstract moves taking
into account the functions described and the prompt questions.
_________________
_________________
_________________
_________________
Adapted from:
(PDF) Chapter: Abstracts: Cross-linguistic, Disciplinary and Intercultural Perspectices.
Writing Abstracts
30
b) In this abstract, label the different moves.
CNR, National Research Council of Italy, Collegio Carlo Alberto, Via Real Collegio,
30-10024, Moncalieri, Torino, Italy
Abstract
Source:
Coccia, Mario, 2022. "Probability of discoveries between research fields to explain scientific and technological change," Technology in
Society, Elsevier, vol. 68(C).
https://doi.org/10.1016/j.techsoc.2022.101874.
https://www.sciencedirect.com/science/article/abs/pii/S0160791X2200015X
31
c) In the following abstract, which moves can you identify?
Abstract
Organoids are 3D structures grown from pluripotent stem cells derived from
human tissue and serve as in vitro miniature models of human organs. Organoids
are expected to revolutionize biomedical research and clinical care. However,
organoids are not seen as morally neutral. For instance, tissue donors may perceive
enduring personal connections with their organoids, setting higher bars for
informed consent and patient participation. Also, several organoid sub-types, e.g.,
brain organoids and human–animal chimeric organoids, have raised controversy.
This systematic review provides an overview of ethical discussions as conducted in
the scientific literature on organoids. The review covers both research and clinical
applications of organoid technology and discusses the topics informed consent,
commercialization, personalized medicine, transplantation, brain organoids,
chimeras, and gastruloids. It shows that further ethical research is needed
especially on organoid transplantation, to help ensure the responsible development
and clinical implementation of this technology in this field.
d) Comprehension check.
32