IHIS PAGE

Vitamins
Micronw hien. OrOrjanie y snongenic Compound
whi ae mo qhantittes to
nemal healt egaom - vitaminu s
Minoy ails
Vitamins ae essenkal gonie enpound
that Yequirad shal q,nenti ties fer
Natiet & bichemi al funhons such as
Co- en24mes motabolic Roaction, eleehon
donsrs, antiozidnts trans erip tion etectess.
be ertactod om fod and
They
Supplement o Korme Cases Synthis
(o) intestinal miccobeg.
kedyVitamy
Fat soluble Watin solubli
Viti A,D,E K. BComplNon (omplez
Enegy Reliing Hemato
Poiic
Vit-c
VitaB ,B2, B3, Bs, B6 iB7. folica CBa) B2
 Fat (AD,E S) Wate
lub)e in lipids ( obl
solctio
not n aqneeves
soluions.

Lmovtant invi in Vsad as

bone fon mation,atioidand Cofactors bg

Not

bdy
Vitamin -A

ulatel
St Consists
substencas
chenically sbiclgtaly
Rrawn as Potinoid.
Conis t Rotinol
Petn a
Petinoic aceo
auo
R-cHO’ petina
R
CHOH Retinot
R- Coou ’ Rotinoie ad
p-Ionone

RDARa Conmanded Die

Di etoy Allowan)
Adulyi keot qcg Cscooto| doy)
Pr nn y; too -126o
Laetotin! 1200 - 4o0 CAooIu lday
 Dieoiy soyeCes
Negelete sOWee lortaun the Provi tamyn
B- Casodme, yellaw dack giun veyelabl
nd ruils aie
Castol, spinach, pupken, mange,
ete

Liver,
ae
dhay, olle melk, chege , battr,
fishcCod o) shak) ive ols oe nh

hioo yans port STorag

(x) Plant Sowus (ortah tte provitamin
B- Caratne whuih to

(amceus) ot Retinal.
B- Caothe Calolznsy a Rotinal
cioygeran.
(Animal Souee cordoun potingt ests
Rtingt ate ipid Rotina + ffA
esteras
Bot Retind &potinal abcope into
inlutinal coal alls with the helo
Bilo Ralta
 Retina Tuetion gwes Retino
Retinal ptina, potindEAy
Rodutase
estificotim Retingl ata
Petin to Reinol
dylnion,
esle tied
wi tt
tatty acds t fom ehingl etie whit
ae in ovpor attl nto
chylomiCuns
eeasel
Petinyl esba * chylmi on
t) As awhen neode d, vitA s helast fom
fse Retnol
petinol s tans potd n tte iYalatien
by tt (Plasma) Retinol Binding Prolani
(R8 p). Each Rof binds with moleus
RBP» binoling is to Prevent tta ea uhin
wit A thio widnoys)

()qs. vit n Sterel liwes

hwee
Prestnt
the ivee
 THIS PAGE

planty JAnimals
B-Conotene Reti ny eslis

Tntestinal el Retinol.
B-Cootine

Retinal Roting
Retinol Al hans ehino)
J,
Reti ng estiw Al|-tiany petinal

visud yue
chylomieona
Live AL-trans
,retinol Retinol Tacget ay
RBp
RotinoRBp Retin
RA
 Biochemi cal functionu vit 9.
L Role in
> Retina Cona two
Retinal]:
eept calls
) Rods Cones whch Contan visnal Pgmanlk
callkd
Rhodapsin photpdn
>hee pmen Conjugatd psotn wh.
Catain opsin A + |-cio. Rotina
(Proan)
’|- cis Retina n esentha fon the absphion
a Selies
ct photochemical Reahina.
taksplae
ate
which ne senccd thiagh the cpla
neves and Sends the
the vs al centa. sigral
Rads aste
Rasponi ble for Voin a dein Lght
Corus are hponibe
sponibe fen Voion
and colous voien. bonght iglht
Rhodopsin Cvisual pigment) Rhodops
Çov
OPSin Wald
)- cis Retinal ALL brans -ye tina Visual
Ruhing
cu RotinalKin etina trans-Retinal
Bloed Blo

Evex i-Rotinal br-ns -Retinal

ADH NADA NADH+y
AleheClwe)."
dehydhogerase CAP)
NApt
Zsomeiak. LAl- trens Retinol
1)- cis - Retind
 when the dght ghiees on the pimont
series photochemial
dokuplae blaching eactions
and spsun. witt sepasal
Psomn lotin a l|-is Retinal to nu- trans
Phoduus
whhih polaisalion in te Retinal Coll membotinal
iansfered as hele Signale to
brain.
ALL- kans etinal is
hotinal ibomeiase Ciiimmepliately is omenised by
Retnal epithellium) to
|- tis
Rotina. Thio Combines with oPin t
Agenekati shoolepsin Complite he Viaal
) How
eve, tte ConveLsion o all -tians Retinal to
I)- is Rotinal is in
sn lompleti. Theutore, mastst te al
tans einal i hansportiol to t0 ttu
tte we
Convestual o al - Rars retin by a
chl
dhydgenatthe
Csomenation to |- cio
al - tians hitirdnol urdgoey
vetnol which i then
pTodised o Il- cto etna' to
Vo ual posticpats 1n he
Dark A
daptation !.
( The me tabon L the forma tion ot
Rhadopsin is knawn as Dark adaptaton time.
o Depende in the eNailabilty et VitA, the
of tt tigment
Qdaplation
eleacbing Colauut Rhodopin, changs from tion Ped to yelo
dumng Con tirrmat ona Chang).
Role Ivit A) Retinojc aud as Hormone
(or)
Mechanon 8 oon of vit A (a Rhinse au)

Retinol einalLy p tinoic acod

Live Blood
estu petinol
RBP
R&A
RBP Rno
binding
Petinal Proleen
Reti no'c aud. C8P ollwa binding

RA Nuclia Receptn
slesponsc elernen
n-RA

speit pralutProtetns aie

ll ditt elon hato
actera
Retinol s a ohotmone
to tte which
Retioic aiel whnc

Hses BOh,tath , let, ,

acellla - Rohnd- bindung Stet)
to tte
prden that Cauies vit A
nulo binds pn DNA., Hoe it acto he
stooid hotms g Cavo the tian
latis
speüti fao lais Aeguidel cella dlitheentol
ihey nction START WITH THIS PAGE

Rctinol Peti noic aned

anot
dike St sod uncion al tmutt
Pho tin
homones
homonesThey reylat the
cell
Synthew and the ate in volv ed wn Tt
outh s di tteen halim
A
e8serlia to manlan halthy epthd
,due to te ettect 8
to Prvest pctincic at
Jeratin dynthnu
oe
boras s toeth
vit A in he torm Yetinoic acid indus ta
Ccbendqti n,
bone mabiz glyto
facts which ase
halptul
a bonec s cat lag. also
in . fomahm
ndus
fomat
Role
(genral) gvfuth development:
RA
produces 91cwh factos which
epitheliad ells
Jgnttae
gycoproten whill
(8 EPHthelialisatton'
vit n is essenti to to mantai helthuy
epihel
Ro poduo speuli proten whil helps
matuaton
int mate
Retina
seeretory epitheli tsues n
onjuctiva, skin, aIT, vT, D, eh e
wit A Prevento Keratn Syntheoy
keratnsatm
hyp
whech prevent

nco polysachai do whelh mainteni tte

moist Susdae
Reprooluhn'
js neceas aly r nomal
seoducf on by Paoventing eerati i 2atin
atphy geneital hact (degenea hi

Spem count pwento mS Catiage

s Canoensids (B- Cadone ) unchno as ant ai dlend

and heelue ìst Co0 0s iti alef by
tua dhaclilalo stere sthong 0ç
danls
BCaroono alo tound to be bohiy'iat to
heant toks oue to ts anti prerey
idan Propoy
 prapes main lanen a
tew

Sntechord
abe essenlia/ fn Th nthuny
brans fenin (Tsen iansprt P)fp
quicd for chlehe Jyottuw
VitA s gluoneogenws.
Detiien y of vit A:
peiieny manifestations o tu eyes'
) Nght Blind nes )Nc talopia!. is ohe
easliest
dafiueng.
The tndividalo have ittiety osae àn dim
dt.
Sine the dak adaptalon tme is inzeased.
prolngd detiueny ireveri bly damago aa nember
x enophthalmia; ore tn tene difiieny nevmal eseli
ckhatini sed Produceel
itt o seplad by fatened keatinized heapd
gtyati fied epithalium 0n Conuctva X Retina.
Laima gland sadng to dynes thichaning
Coniueh'va.
) while, thuch,tiargulae plag ues
(on Jle lonjuesva alled B ol! spo
 kelatomalaca..
Eucthe Sevele deti u'eny eado o
Sottonny, uleatien anel degeneatn
Coinea eadeng to Corneal peLtoratins. Deohucf
Coi naa ketbeico ao oya to
total blune ness
malaa (aum nsy
otte debi ienly manifesta hy'
Eeton yau. vit-A dLt lstettb in growtt
Asto daten due to fmpasment
EHect on keproduchm. qenntion ot gemi ra
epithelium leodls to ctemlq à mals, miSCatiaige
mfemale.

(RThe
beomo rough dy erati ~2atinn
epHhelias ullo 9astointesti nal
tyact Unnan
tyat restpi rato ta et io
tu inenea notied Thy
v asowalid
paclmd
wih infeetn
formation
(eads
vit n dA
nay
Oplasma RRP (vel d dand
vìt n dcf
aro ocay
Eteet on Tmmen ty.
19 synthnie, hena
Vit A def? ammeno polenty
X