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Treatment of Schizophrenia

Family Assessment and Intervention

Edited byM. J. Goldstein, I. Hand, andK. Hahlweg

With contributions by
C. M. Anderson, B. Barbaro, R. Berkowitz, G. Buchkramer,
A. Cechnicki, L. J. Cozolino, B. Dulz, R. Eberlein-Vries,
I. R. H. Falloon, M. J. Goldstein, K. Hahlweg, I. Hand,
J. M. Hooley, J. H. Jenkins, M. Karno, L. Kuipers, J. Leff,
L. Lewandowski, R. P. Liberman, D. J. Miklowitz,
H. J. Moller, K. Nuechterlein, D. Ploog, F. Santana,
W. Schmid-Bode, H. Schulze-Monking, A. de la Selva,
A. M. Strachan, F. Strian, D. Sturgeon, A. Szymusik,
C. E. Vaughn, H. U. Wittchen, C. Wittgen, L. C. Wynne,
J. Zadecki, K. Zawadzka, D. v. Zerssen

With 28 Figures and 18 Tables

Springer-Verlag
Berlin Heidelberg New York Tokyo
Prof. Michael J. Goldstein, Ph.D.
University of California, L.A.
Department of Psychology
1283 Franz Hall
Los Angeles, CA 90024
USA

Prof. Iver Hand, Dr. med.


University of Hamburg
Department of Psychiatry
Martinistrasse 52
D-2000 Hamburg
FRG

Dr. phil. habil. Kurt Hahlweg


Max Planck Institute of Psychiatry
Kraepelinstrasse 2
D-8000 Munchen 40
FRG

ISBN-13: 978-3-540-16628-3 e-ISBN-13: 978-3-642-95496-2


DOl: 10.1007/978-3-642-95496-2

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is
concerned, specifically those of translation, reprinting, reuse of illustrations, broadcasting, reproduc-
tion by photocopying machine or similar means, and storage in data banks.
Under § 54 of the German Copyright Law, where copies are made for other than private use, a fee is
payable to Verwertungsgesellschaft Wort, Munich.
© by Springer-Verlag Berlin Heidelberg 1986

Product Liability: The publisher can give no guarantee for information about drug dosage and
application thereof contained in this book. In every individual case the respective user must check
its accuracy by consulting other pharmaceutical literature.
The use of registered names, trademarks, etc. in this publication does not imply, even in the absence
of a specific statement, that such names are exempt from the relevant protective laws and regulations
and therefore free for general use.

2119/3321-543210
Contents

Contributors VII
h~. ~
Introduction:
Treatment of Schizophrenia: Historical Aspects (D. Ploog and F. Strian) 1

A. Prediction ofthe Course of Schizophrenia


1. Patient Attributes
1. Outcome and Prediction of Outcome in Schizophrenia: Results from the Litera-
ture and from Two Personal Studies (H. J. Moller, W. Schmid-Bode, H. U.
Wittchen, and D. v. Zerssen) 11

II. Family Attributes


2. An Introduction to EE Measurement and Research (J. M. Hooley) 25
3. Expressed Emotion in Cross-Cultural Context: Familial Respones to Schizo-
phrenic Illness Among Mexican Americans (1. H. Jenkins, M. Karno, A. de la
Selva, and F. Santana) 35
4. Do Relatives Express Expressed Emotion? (A. M. Strachan, M. J. Goldstein,
and D. J. Miklowitz) 51
5. Short-Term Relapse in Young Schizophrenics: Can It Be Predicted and Affect-
ed by Family (CFI) , Patient, and Treatment Variables? An Experimental Study
(B. Dulz and I. Hand) . 59
Comment on Chapter 5 (C. Vaughn) 76
6. Emotional Atmosphere in Families of Schizophrenic Outpatients: Relevance of
a Practice-Oriented Assessment Instrument (G. Buchkramer, H. Schulze-Mon-
king, L. Lewandowski, and C. Wittgen) 79
7. The Marriages and Interaction Patterns of Depressed Patients and Their
Spouses: Comparison of High and Low EE Dyads (J. M. Hooley and K. Hahl-
weg) 85
8. Patterns of Emotional Response in the Families of Schizophrenic Patients (C. E.
Vaughn) 97

B. Modification of the Course of Schizophrenia by Family Interventions


9. Working with Families of Acute Psychotics: Problems for Research and Recon-
sideration (L. C. Wynne) . 109
10. Family Education as a Component of Extended Family-Oriented Treatment
Programs for Schizophrenia (L. J. Cozolino and M. J. Goldstein) . 117
11. Pilot Study of the Impact of a Family Education Program on Relatives of Re-
cent-Onset Schizophrenic Patients (L. J. Cozolino and K. Nuechterlein) 129
12. Psychoeducational Family Therapy (c. M. Anderson) 145
13. Controlled Trial of Social Intervention in the Families of Schizophrenic Patients
(J. Leff, L. Kuipers, R. Berkowitz, R. Eberlein-Vries, and D. Sturgeon) 153
14. Behavioral Family Therapy for Schizophrenia: Clinical, Social, Family, and
Economic Benefits (I. R. H. Falloon) . 171
VI Contents
15. The Impact of Family Intervention Programs on Family Communication and the
Short-Term Course of Schizophrenia (M. J. Goldstein and A. M. Strachan). 185
16. The Psychosocial Program of Treatment of Schizophrenic Patients in the
Crakow Psychiatric Clinic (B. Barbaro, A. Cechnicki, A. Szymusik, K. Zawad-
zka, and J. Zadecki) 193

Epilogue
17. Coping and Competence as Protective Factors in the Vulnerability-Stress Model
of Schizophrenia (R. P. Liberman) 201

Subject Index . 217


Contributors

Carol M. Anderson, Ph.D., University of Department of Psychiatry, Martinistrasse


Pittsburgh, Western Psychiatric Institute, 52, D-2000 Hamburg, FRG
3811 O'Hara Street Pittsburgh, PA Jill M. Hooley, Ph.D., Harvard University,
15213, USA Department of Psychology and Social
Bogdan Barbaro, M.D., University of Cra- Relations, William James Hall, 33 Kirk-
cow Medical Academy, Zwierzyniecka land Street, Cambridge, Massachusetts
15/8,31-108 Cracow, PL 02138, USA
Ruth Berkowitz, Ph.D., MRC Social Janis H. Jenkins, Ph.D., University of Cali-
Psychiatry Unit, Institute of Psychiatry, fornia, Los Angeles, Department of Psy-
De Crespigny Park, GB-London SE 5, chiatry, 760 Westwood Plaza, Los Ange-
GB les, CA 90024, USA
Gerhard Buchkramer, Dr. med., Psychia- Marvin Karno, M.D., University of Cali-
trische und Nervenklinik der Westfali- fornia, L.A., Department of Psychiatry,
schen Wilhelms-Universitat, Albert- 760 Westwood Plaza, Los Angeles, CA
Schweitzer-StraBe, D-4400 Munster, 90024, USA
FRG Liz Kuipers, B.Sc., M.Sc., MRC Social
Andrzej Cechnicki, M.D., University of Psychiatry Unit, Institute of Psychiatry,
Cracow Medical Academy, Zwierzy- De Crespigny Park, GB-London SE 5,
niecka 15/8, 31-108 Cracow, PL GB
Louis J. Cozolino, Ph.D., Department of Julian Leff, M.D., MRC Social Psychiatry
Psychology, University of California, Unit, Institute of Psychiatry, De Cres-
L.A., 1283 Franz Hall, Los Angeles, CA pigny Park, GB-London SE 5, GB
90024, USA Ludwig Lewandowski, Dr. phil., Psychia-
Birger Dulz, Dr. med., Allgemeines Kran- trische und Nervenklinik der Westfali-
kenhaus Ochsenzoll, Langenhorner schen Wilhelms-Universitat, Albert-
Chaussee 560, D-2000 Hamburg 62, FRG Schweitzer-StraBe, D-4400 Munster,
Rosemarie Eberlein-Vries, Dr. med., Psy- FRG
chiatrische Universitatsklinik, NuB- Robert P. Liberman, M.D., University of
baumstraBe, D-8000 Munchen 2, FRG California, L.A., Brentwood VA Medi-
Ian R. H. Falloon, M.D., University of cal Center, 11301 Wilshire Blvd., Los
Southern California, School of Medicine Angeles, CA 90073, USA
Los Angeles; Correspondence: Bucking- David J. Miklowitz, Ph.D., University of
ham Hospital, High Street, Buckingham, California, L.A., Department of
MK181NV,GB Psychology, 1283 Franz Hall, Los Ange-
Michael J. Goldstein, Ph.D., University of les, CA 90024, USA
California, L.A., Department of Psycho- Hans-Jurgen Moller, Dr. med. Psychiatri-
logy, 1283 Franz Hall, Los Angeles, CA sche Klinik und Poliklinik Rechts der
90024, USA Isar, Technische UniversiHit Munchen,
Kurt Hahlweg, Dr. phil. Max Planck Insti- MohlstraBe 26, D-8000 Munchen 80,
tute of Psychiatry, Kraepelinstrasse 2, D- FRG
8000 Munchen 40, FRG Keith Nuechterlein, Ph.D., University of
Iver Hand, M.D., University of Hamburg, California, L.A., Department ofPsychia-
VIII Contributors
try, 760 Westwood Plaza, Los Angeles, Adam Szymusik, M.D., University of Cra-
CA 90024, USA cow Medical Academy, Zwierzyniecka
Detlev Ploog, Dr. med., Max Planck Insti- 15/8,31-108 Cracow, PL
tute of Psychiatry, Kraepelinstrasse 2, Christine E. Vaughn, Ph.D., Salfort Com-
D-8000 Munchen 40, FRG munity Health Project, Department of
Felipe Santana, Ph.D., University of Cali- Clinical Psychology, Prestwich Hospital,
fornia, L.A., Department of Psychiatry, GB-Manchester; Correspondence: 20
760 Westwood Plaza, Los Angeles, CA Beverly Rd., GB-Cholchester, Essex C03
90024, USA 3NG,GB
Willi Schmid-Bode, Dr. med., Max Planck Hans-Ulrich Wittchen, Dr. phil., Max
Institute of Psychiatry, Kreapelinstr. 10, Planck Institute of Psychiatry, Kraepelin-
D-8000 Munchen 40, FRG str. 2, D-8000 Munchen 40, FRG
Heinrich Schulze-Monking, Dr. med., Psy- Connie Wittgen, Dipl.-Psych., Psychiatri-
chiatrische und Nervenklinik der Westfa- sche und Nervenklinik der Westfalischen
lischen Wilhelms-Universitat, Albert- Wilhelms-Universitat, Albert-Schweit-
Schweitzer-StraBe, D-4400 Munster, zer-StraBe, D-4400 Munster, FRG
FRG Lyman C. Wynne, M.D., Ph.D., Univer-
Aurora de la Selva, M.Ed., University of sity of Rochester, Medical Center,
California, L.A., Department ofPsychia- Department of Psychiatry, Wing R, 601
try, 760 Westwood Plaza, Los Angeles, Elmwood Avenue, Rochester, NY
CA 90024, USA 14642, USA
Angus M. Strachan, Ph.D., University of Jerzy Zadecki, M.D., University of Cracow
California, L.A., Department of Psycho- Medical Academy, Zwierzyniecka 15/8,
logy, 1283 Franz Hall, Los Angeles, CA 31-108 Cracow, PL
90024, USA Krystyna Zawadzka, M.D., University of
Friedrich Strian, Dr. med., Max Planck Cracow Medical Academy, Zwierzy-
Institute of Psychiatry, Kraepelinstr. 10, niecka 15/8, 31-108 Cracow, PL
D-8000 Munchen 40, FRG Detlef von Zerssen, Dr. med., Max Planck
David Sturgeon, M.D., Department of Institute of Psychiatry, Kraepelinstr. 10,
Mental Health, School of Medicine, Uni- D-8000 Munchen 40, FRG
versity College, London WC 1, GB
Preface

A group of people are seated together in a tried to explain it to you, you wouldn't un-
room. Recently, they have shared two derstand,' and this went on and on in a big
important experiences - they have lived circle, nowhere, - no information at all!"
with a close relative, usually an offspring or The feelings of these relatives are not
spouse, who has been through an episode unique. Until recently, many relatives of
of a major mental disorder, most often of a schizophrenic patients experienced some
schizophrenic type, and they have also been form of rebuff by mental health profes-
participants in an experimental program sionals while their relative was treated as an
designed to assist them and their disturbed inpatient and little or no involvement in the
relative in modifying family patterns to aftercare process when the relative re-
foster rehabilitation. The experimental turned home. These attitudes of mental
programs involve maintenance pharmaco- health personnel reflected both the prevail-
therapy as well as a combination of family ing wisdom of the time that the family, be-
education and therapy. Since a number of cause of their pernicious impact, needed to
the relatives had experienced the problems be isolated from the patient and his treat-
of dealing with a mentally ill relative before ment, as well as a sense of helplessness
such a program existed, they were asked to concerning what information and advice
compare their current experiences with could be provided that would be useful and
earlier ones. An interviewer asket about helpful.
previous experiences with mental health The tendency to isolate and dissociate the
professionals when the relatives asked for relatives of severely disordered mental
information about their offspring or patients fit rather well with the treatment
spouse's mental disorder. One mother an- pattern existing in the United States and
swered: elsewhere from the end of World War II
Everything seemed to be kept such a dark secret until the early 1960s. Patients, when symp-
from the parents, from the people that are tomatic, were removed from their families
involved - whether that's the thing to do, I dont't for an extended inpatient stay. If and when
know, but I think that the parents need a lot of
support in whatever the program, the psychiatrist
released, they rarely returned to parental or
didn't give us that much. He was dealing with the spousal homes. Also, when patients were
patient but not with the family. released during this period, they frequently
had achieved reasonable levels of remission
A father from another family echoed these from their psychosis so that when they did
feelings of isolation, "We had the same return home relatives did not have to deal
problems, they would deal with the patient with active psychotic symptoms.
but not with the family at all. Everyone that The patterns of care which have evolved
our son went to, 1 mean, we went but that since the mid-1960s have forced both men-
was it. We were there, but we never saw tal health professionals and families of men-
anybody." The interviewer asked, "Did tal patients to rethink their respective roles.
you ask to see somebody?" The father Especially in the United States, the pattern
replied, "Yeah, you could see them, but of community care for schizophrenic pa-
they never had time to talk to you." tients has evolved into a two-phase ap-
Another mother from still another family proach in which a relatively brief inpatient
stated, "I first got absolutely nowhere, they stay is followed by extended aftercare in the
would tell me, 'You won't understand if 1 community. Because adequate transitional
X M. J. Goldstein et al.
living environments are rare, and even associated with a high probability of re-
when they do exist patients resist staying in lapse, actually alter the short-term course
them, patients frequently return to a family of the disorder? The first half of the book is
environment in varying states of partial re- oriented to reports which address these
mission. Examination of these family envi- significant questions.
ronments and the problems of reentry of a Although the focus of this book is on the
disturbed and frequently disturbing relative prognostic value of family attitudes, we
has revealed that families often experience have not ignored the significance of individ-
considerable difficulty in fulfilling the ual patient attributes as predictors of the
newly assigned role of primary caretaker. course of the disorder. Therefore a chapter
Even when families appear to cope well, discussing this issue is presented.
there is a notable impact on the mental The awareness that family members are
health status of relatives. In one study by increasingly responsible for the aftercare of
Hawks (1975), 50% of the relatives stated schizophrenic relatives and that specific
that their own mental health had been ad- attributes of the family environment may be
versely affected in the process of coping particularly pernicious has led to renewed
with the patient's mental disorder. interest in family intervention programs
Further research has indicated that atti- designed to support the family system, pre-
tudes expressed by the relatives toward the vent relapse, and foster the social recovery
returning mental patient are highly predic- of the patient. Many of these family inter-
tive of the likelihood that the patient will vention programs have utilized measures of
remain in the community 9 months after EE to identify the relapse-prone family
discharge from the hospital. The work of units in special need for treatment. Previous
Brown and his associates (Brown, 1959; attempts at using traditional family therapy
Brown, Birley, and Wing, 1972) followed with families of schizophrenics were not
up by Vaughn and Leff (1976) has gone be- successful or widely adopted. Further, these
yond informal clinical observation to pro- programs were, in the past, viewed as alter-
vide empirical evidence that those delete- natives to maintenance pharmacological
rious aspects of the family environment treatment. The newer models described in
associated with high risk for relapse could this volume are not based on such an either/
be specified and measured with standard- or conceptualization, and all, in fact, ac-
ized procedures. Their work on expressed knowledge the importance of antipsychotic
emotion (EE) revealed that relatives' atti- drugs as maintenance agents during the
tudes of criticism, hostility, and/or emo- posthospialization phase of treatment.
tional overinvolvement possess powerful These newer, experimental programs,
prognostic information about the likeli- which are frequently very pragmatic in
hood of relapse. These attitudes, assumed orientation, attempt to provide an addition-
to reflect ongoing family transactions, sug- al psychosocial dimension to aftercare be-
gest a particular sensitivity of the schizo- yond the protection against relapse provid-
phrenic patient to discriminable attributes ed by pharmacological agents.
ofthe family environment. In recent years, several models of family
While research on EE attitudes has been treatment have been developed, which at-
very provocative, there are still a number of tempt to include an educational component
unanswered questions about the construct. as 'part of a larger program of intervention
First, are EE attitudes associated with the for schizophrenic patients and their famil-
course of other psychiatric disorders such as ies. These models have been classified as
depression? Second, are the results gener- psychoeducational family therapies and
alizable to national or subcultural groups have been designed to help patients out of
other than the original English samples in hospitals and to return them to a productive
which the measure was developed? Third, life in the community. Working in tandem
are attitudes elicited during the interview with medication programs, they teach pa-
used to evaluate EE actually expressed in tients and families about the disorder and
family transaction? Finally, does thera- its management. Treating the family as a
peutic manipUlation of these EE attitudes, resource rather than as a stress, the pro-
Preface XI
grams focus on concrete problem - solving One chapter of this section describes a
and specific helping behaviors for coping unique intervention program for schizo-
with stress. These models recognize the phrenia developed by a clinical research
likelihood of a biological basis of the illness team from Poland. Since reports from
and the negative impact of stress on the Eastern Europe of innovative treatment
patient's ability to function. The underlying programs for schizophrenia rarely appear in
assumption of all psychoeducational family conjunction with those from Western Eu-
programs developed to date is that giving rope and the United States, the editors felt
families information about the nature of the that the inclusion of such a report would
disorder, along with specific suggestions for broaden the readers' appreciation of the
coping with it effectively, can decrease the diversity of family-oriented programs for
intensity and conflict inherent in family life schizophrenia which are emerging world-
and thus reduce the likelihood of (a) relapse wide.
in the index patient and (b) the emergence These topics were extensively discussed
of mental disorders in the previously non- and evaluated in two consecutive research
affected relatives. planning workshops, which were held on
These programs appear to have certain May 5-7, 1982 in San Diego, California
common components; (a) the establishment (USA) and on June 21-24, 1983 at SchloG
of a collaborative relationship between Ringberg, Bavaria (FRG). The first work-
therapist( s) and family members, (b) the shop was sponsored by the Department of
provision of information and support, and Psychology, UCLA, and the Office of Pre-
(c) the creation of highly structured pre- vention, Center for the Study of Schizo-
dictable environments in the treatment set- phrenia and Psychopharmacological and
ting and in the home. Somatic Research Branch, all of the Na-
While these commonalities exist, there tional Institute of Mental Health (NIMH).
are also substantial differences in the pro- The second workshop was sponsored by the
grams developed to date in terms of the Max Planck Institute of Psychiatry, Munich
type and detail of information provided (FRG).
about schizophrenia; the format of these Most of the chapters in this book repre-
family education programs (patients pres- sent papers that were presented at the
ent or not), the format of the extended fam- workshops. However, many of them have
ily therapy phase (relatives only vs family been altered or extended to reflect issues
and patient), the context of the extended raised during the formal and informal
family program (home vs clinic based), and discussions that followed each presenta-
the duration of these programs ranging tion. The epilogue in particular was written
from 6 weeks following discharge to to provide a comprehensive discussion of
programs lasting over 1 year. these various issues.
The variations in key dimensions of the It is difficult to characterize, on a printed
programs tested in controlled trials to date page, the emotional climate of both work-
warranted closer scrutiny to evaluate what shops. However, it was tremendously hear-
direction future research on preventive in- tening to us (as the organizers) to partici-
tervention programs for families with a pate in the sessions with professionals who
mentally ill relative should take. were not only extremely knowledgeable
The second half of the book deals with about their subject matter, but who were so
some of the more innovative family treat- enthusiastic in sharing their ideas and ex-
ment programs that have been tested in periences with each other with an absolute
controlled clinical trials in the United States minimum of defensiveness and posturing.
and Great Britain. In addition, we present There was a general feeling among the par-
some data concerning the impact of one ticipants that both workshops were a pro-
such program on family interaction, using foundly enriching experience.
procedures described earlier in this volume It is our hope that some of that flavor will
for measuring the correspondence between carryover to the reader and will stimulate
EE attitudes and directly observed family both clinical practice and research in the
behavior. difficult area of schizophrenia.
XII M. J. Goldstein et al.
References
Brown, G. W. (1959). Experiences of discharged Hawks, D. (1975). Community care. An analysis
chronic schizophrenic mental hospital patients of assumptions. British Journal of Psychiatry,
in various types of living group. Millbank Me- 127,276-285.
morial Fund Quarterly, 37, 105-131. Vaughn, C. E., and Leff, J. P. (1976). The in-
Brown, G. W., Birley, J. L. T., and Wing, J. K. fluence of family and social factors on the
(1972). Influence of family life on the course of course of psychiatric illness. British Journal of
schizophrenic disorders: A replication. British Psychiatry, 129, 125-137.
Journal of Psychiatry, 121,241-258.

M. J. Goldstein, I. Hand, and K. Hahlweg


Introduction: Treatment of Schizophrenia:
Historical Aspects
D. Ploog and F. Strian

The history of the treatment of schizophre- At the same time, however, it was pointed
nia reflects the continuing problems of es- out that in the case of an acute state of agita-
tablishing the etiology, even though today tion, hypnotics and narcotics "as a rule are
there is agreement that there has to be a of little use" (Kraepelin, 1899). Since schiz-
genetic disposition before schizophrenia ophrenic disorders were considered to be
will develop. As with all etiologically un- "the result of compound influences acting
clarified diseases, there are numerous etio- over a long period of time and gradually
logical hypotheses and therapeutic treat- having an increasingly profound effect," it
ment methods, with a corresponding dan- was not expected that rapid recovery would
ger of treatment methods being based on a result from administering drugs (Kahl-
priori assumptions or uncritical prag- baum, 1874). On the other hand, in the pre-
matism. Even the assessment of the effec- vious century psychiatry already had at its
tiveness of treatment, however, is closely disposal a wide variety of nursing methods
linked with valid diagnostic and assessment and psychological, social, and ergothera-
criteria, which have only recently become peutic approaches. An important part was
the object of intensive study (Carpenter, played by what was known as "moral treat-
Heinrichs, and Hanlon, 1981). ment," which evolved as early as the first
In the history of the treatment of schizo- half of the nineteenth century in England,
phrenia, the uncertainties with respect to France, and the United States and which
diagnosis, etiology, and therapy are re- essentially corresponded to present-day
flected not only in the relatively large varie- sociotherapy. Even before the turn of the
ty of therapy practiced but also in the century, "no restraint" treatment had not
marked influence of contemporary trends only shown itself to be of therapeutic value,
and cultural aspects, with swings between but the abandonment of rigorous restric-
biologically and psychologically biased ap- tions and physical restraint had also led to a
proaches. It can clearly be seen how fatal decrease in states of dramatic agitation.
any extreme position with regard to diagno- Committal was practiced to nurse the pa-
sis and therapy (e.g., a heavily biased genet- tient in an acute phase, but also to shield
ic or psychoanalytic approach) can be for him from provocative environmental influ-
both patient and psychiatrist. In between ences. In some cases, psychodynamic and
these extreme positions, however, there is a behavioral therapy approaches seem to
wide range of somatic and psychological have been anticipated. Kahlbaum, for ex-
therapies that individually and in combina- ample, wrote in 1874 that the goal of every
tion have without a doubt considerably therapy should be "to strengthen and rein-
ameliorated the situation of the schizo- force the ego and to save it from suppres-
phrenic patient. sion and disintegration." To that end, the
When schizophrenic psychoses first be- individual's premorbid imagination and
gan to be medically understood there were emotions were to be stimulated, without
virtually no somatic treatment methods however provoking the psychotic charac-
available. Opium in high doses, also bella- teristics. On the patient's return to his home
donna, quinine, and even digitalis were environment, the avoidance of emotional
tried (Griesinger, 1861; Kahlbaum, 1874). conflicts was considered to be of vital im-
2 D. Ploog and F. Strian
portance. An atmosphere of understanding prophylactic effect. In a review of 35 dou-
and patience would also help to prevent re- ble-blind studies already published, Davis
lapses. et al. (1982) established that long-term
It was not, however, these psychosocial neuroleptic therapy resulted in significantly
aspects, but the fact that schizophrenia in fewer relapses. Of the total of 3606 schizo-
the final analysis was considered to be an as phrenic patients investigated in the studies,
yet unclarified brain disease that was deci- 20% of those treated with neuroleptic drugs
sive for the further development of research but 53% of those taking placebos had re-
on psychoses. Kraepelin, in particular, called lapses over a 4- to 6-month time period. Pa-
for an intensive search for underlying neu- tients seemed to gradually relapse over
ronal mechanisms. Looking back at the time, that is, the number of relapses in each
somatic forms of treatment, it becomes month of the treatment appeared to be con-
clear that, with certain reservations, these stant. Neuroleptic drugs were shown to re-
represented the most important advances in duce the expected relapse rate by a factor of
the treatment of schizophrenic disorders. 2.5. When noncompliance patients were ex-
This is substantiated by a number of factors cluded, this factor rose to approx. 5.0. One
such as, for example, the improvement of year after hospital discharge, the average
the patient's condition, the shortening of relapse rate was 41 % for patients receiving
the hospitalization period, the decrease in active medication with a corresponding rate
the number of readmissions, and better of 68% for patients receiving placebo treat-
vocational and social reintegration. Thus, ment (Hogarty, 1984).
for example, the introduction of insulin and Maintenance treatment has been shown
convulsive treatment in the 1930s (Cerletti to produce significant results only when suf-
and Bini, 1938; Sakel, 1935) and the intro- ficiently high doses are administered. In a
duction of neuroleptic drugs in the 1950s group of schizophrenic patients treated
(Delay and Deniker, 1952, 1956) drasti- with low doses of Fluphenazin decanoate
cally, almost exponentially, reduced the (1.25-5.0 mg biweekly), the relapse rate
period schizophrenic patients spent in hos- was significantly higher than in a group
pital (Davis, Tanicak, Chang, and Kler- treated with a standard dosage (12.5-50.0
man, 1982; Meyer, 1984; Meyer, Simon, mg biweekly) (Kane, Rifkin, Quitkin, and
and Stille, 1964). In approximately the Klein, 1979a, 1979b). However, relapses
same way, it was possible to reduce the se- tended to be less severe when compared to
verity of the illness (Saarma, 1983). Since relapses in the standard dosage group
the introduction of neuroleptic therapy in (Kane et aI., 1983).
particular, the once common practice of Some words of caution are necessary with
physically restraining agitated patients as regard to long-term neuropleptic treat-
well as compulsory committals have be- ment. First, individual prognostic criteria
come the exception rather than the rule are still lacking. Consequently, treatment is
(Brill and Patton, 1959). In addition, not prescribed on the basis of individual
neuroleptic treatment has entirely replaced parameters but of overall criteria such as
insulin treatment, and electroconvulsive the chronicity of the disease (Gaebel and
therapy is practiced in only a limited num- Pietzcker, 1983). Second, drug-induced
ber of cases. The neuroleptic spectrum was tardive dyskinesia presents a serious prob-
broadened, and depot preparations in par- lem. It is estimated that after 4 years of
ticular have led to marked progress in long- neuroleptic treatment about 12% of the pa-
term treatment. It is now possible to identi- tients develope these largely irreversible
fy or predict side effects with greater cer- side effects (Kane, Woerner, Weinhold,
tainty, and in the case of long-term treat- Wegner, and Kinon, 1982). To avoid tar-
ment, it has become easier to balance out dive dyskinesia, new treatment approaches
desirable and undesirable neuroleptic ef- were tested, mainly low dose treatment
fects. (Kane et al., 1983) or intermittent treat-
It has recently been shown that in addi- ment in which the neuroleptics are with-
tion to their immediate antipsychotic effect, drawn and reintroduced whenever the pa-
neuroleptic drugs also have a long-term tient complains about prodromal signs
Introduction 3
(Carpenter, Stephens, Rey, Hanlon, and Although even before the turn of the cen-
Heinrichs, 1982; Herz, Szymanski, and tury and before Freud there was a great deal
Simon, 1982). Further research will show of interest in neurotic and hysterical disor-
how effective these approaches will be. ders as well as in appropriate therapeutic
Although in recent years new antipsycho- measures (such as hypnosis), this did not
tic drugs such as molindone, loxapine, and extend to psychotic disorders. It was quite a
pimozide have been developed, expecta- while before even Freud began to study the
tions in the field of psychopharmacology as problem of the psychodynamics of psycho-
to the development of selective or basically ses, and then he applied mechanisms that
new substances have not yet been fulfilled. he had established in connection with neu-
Except in a few specific cases, propranolol roses. [In the case of Schreber, incidentally,
seems to be mainly effective through poten- according to today's diagnostic criteria, the
tiation of neuroleptic drugs (Peet, 1981). patient was not suffering from paranoid
The effectiveness of lithium in schizophre- schizophrenia, but from endogenous de-
nia, excluding the schizoaffective forms, pression, probably of the bipolar type
does not yet seem to be sufficiently estab- (Koehler, 1981)].
lished (Delva and Letemendia, 1982), and The absence of a completely independent
hemodialysis in schizophrenia has been theoretical basis for psychoanalytic psycho-
shown to be a mistake (Skrabanek, 1982). sis therapy is probably also part of the ex-
No actual new alternatives to neuroleptic planation for the generally discouraging re-
treatment are yet in sight. sults. It can in general be seen that among
Parallel to somatotherapy, psycho- and the psychotherapeutic methods of treating
sociotherapeutic measures, though with schizophrenic psychoses, psychoanalytic
varying temporal and regional importance, methods have become much less popular
always played a part in the treatment of and methods aiming at the patient's social
schizophrenia. An early example of the ef- integration and rehabilitation have gained
fectiveness of social support comes from in importance. Here the treatment and
American psychiatry around the mid-nine- management of so-called negative symp-
teenth century (approx. 1830-1860) where toms is once again in the foreground.
"moral treatment" in small, open institu- Group therapy should not begin before the
tions where there was no discrimination acute psychotic symptoms have abated and
against the psychiatrically ill was also of at the same time should be oriented toward
considerable benefit to sufferers from schi- concrete everyday problems (Donlon,
zophrenia (Savino and Mills, 1967). These Rada, and Knight, 1973; O'Brien, et al.,
early experiences have been corroborated 1972). Even group therapy is more success-
anew by very recent, well-controlled trans- ful on the basis of neuroleptic drug treat-
cultural studies in which patients remain in- ment (Claghorn, Johnstone, Cook, and
tegrated in extended families and the mani- Itschner, 1974). In general, there will have
festations of psychosis are tolerated more to be a more precise definition of the tlrera-
readily by society. Here, the prognoses for peutically effective variables in psycho-
schizophrenic patients turned out to be therapy, situational therapy, and psycho-
more favorable in Nigeria, India, on the is- social rehabilitation. In their survey, Keith
land of Mauritius, and in Sri Lanka by com- and Matthews (1982) hence came to the
parison with Denmark and the USSR conclusion that all psychosocial therapeutic
(Murphy and Raman, 1971; Waxler, 1979; methods are generally assessed more opti-
World Health Organization, 1979). The re- mistically than the level of knowledge about
sults from research on twins and adopted them merits.
children are also of relevance in this con- On the other hand, a relatively clear pic-
text: on the one hand, they clearly show the ture is obstained by the methodologically
importance of genetic factors in the genesis excellent therapy studies in which the ef-
of schizophrenia, and on the other, do not fectiveness of neuroleptic and psychothera-
exclude the influence of environmental fac- peutic forms of treatment are compared.
tors (Kety, 1983; Kringlen, 1981; Rosenthal These comparative studies, however, are
and Ketty, 1968). mainly concerned with the effects treat-
4 D. Ploog and F. Strian
ment has on acute psychotic symptoms and roleptic treatment were noticeably better
only partially with long-term effects. In than those resulting from psychotherapeu-
these investigations the methodological tic treatment.
problems are not insignificant. A follow-up The question as to which of the psycho-
study, for instance, on a group of patients therapeutic methods used for schizophrenia
first described by Rosen (1947, 1953) gives the best results remains open due to a
showed that a large number of borderline lack of methodologically reliable studies as
cases had been included, and that in addi- well as of criteria for indicating when to
tion, in the long-term outcome of 75% of apply a particular method and establishing
the patients two to five readmissions had how effective it is. With regard to the effec-
occured (Horwitz, Polatin, Kolb, and tiveness oflong-term treatment, moreover,
Hoch, 1958). Results which significantly factors such as the length of time spent in
demonstrated the greater effectiveness of a the hospital (Glick and Hargreaves, 1979;
combination of psychotherapeutic and neu- Herz and Melville, 1980; Platt, Hirsch, and
roleptic drug treatment than of psycho- Knight, 1981), treatment on an inpatient
therapy unsupported by drug treatment basis only or a mixture of inpatient and out-
were obtained in a number of comparative patient treatment (Vanicelli, Washburn,
studies (e.g., Grinspoon, Ewalt, and Scheef, and Longabaugh, 1978), and partic-
Shader, 1972; Hogarty, Goldberg, and ularly the type of clinical aftercare (Linn,
Schooler, 1974a, 1974c; Hogarty, Gold- Caffey, Klett, and Hogarty, 1977; Stein and
berg, Schooler, and Ullrich, 1974b; Lind- Test, 1980) appear to be important.
berg, 1981; O'Brienet al., 1972). It is signif- Although a large number of valid com-
icant, for example, that in the study by parative studies demonstrated the necessity
Grinspoon et al. treatment with phenothia- of neuroleptic drug treatment, these results
zine proved to be no obstacle to psycho- are by no means an argument against psy-
therapy, but was rather found to result in chotherapeutic measures. It is far more a
better therapeutic cooperation and at the question of when which psychotherapeutic
same time fewer withdrawal tendencies on method should be used and with what aim
the part of the patient. Greenblatt, Solo- in view. The results of the comparative
mon, Evans and Brooks (1965), in a com- studies above all point toward therapeutic
parison of neuroleptic and social therapies, measures that can improve psychosocial in-
had already demonstrated that patients tegration and acceptance in the period fol-
who had no drug treatment in the acute lowing hospitalization. In this respect, the
phase of the illness were subsequently less situation today is in many ways analogous
able to profit from long-term psychothera- to the historical developments outlined
py than patients who had been treated with above.
drugs. Also on a pragmatic, rehabilitative level,
Particularly sobering results were ob- social therapy and aftercare today are es-
tained in the effectiveness studies of May, sential components of the treatment of schi-
Tuma, and Dixon (1981), where compari- zophrenia. This is particularly shown by the
sons were made between neuroleptic drugs, experiment in deinstitutionalizing schizo-
psychotherapy, and psychotherapy with phrenic patients since this was only achiev-
basic neuroleptic drug treatment and a con- ed without disastrous consequences for the
trol group with neither psychotherapy nor patient when he could be reintegrated into
neuroleptic drug treatment. Particularly family or social structures or received ap-
when long-term comparisons were made, propriate aftercare (Braun et al., 1981;
substantially better results were obtained Johnstone, Owens, Gold, Crow, and Mac-
for both the groups receiving drugs than for millan, 1981). The importance of including
the groups that had not received drugs. Al- the family in aftercare is clearly demon-
though the comparison is open to criticism strated by the family assessment and thera-
on account of the limited experience of py studies which are included in this vol-
some of the therapists, as well as the short ume. It is therefore not necessary to review
duration of psychotherapy, once again the these results. However, it must be pointed
long-term effects resulting from initial neu- out that it is not very likely that communica-
Introduction 5
tive structures are of specific significance in cial importance is something that still has to
connection with schizophrenia since social be proved. In any case, such concrete pat-
support also improves prognosis in other terns of interaction present an opportunity
psychiatric and even in most organic dis- of bringing about behavior changes without
eases (Strian, 1983, 1984). Whether the the individuals involved having to be bur-
particular sensitivity and anxiety on the part dened with unproductive questions as to
of the schizophrenic patient in response to a circumstances and persons in their environ-
critical, overprotective, and adverse envi- ment that might be responsible for the ill-
ronment ("expressed emotion") is of spe- ness.

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Introduction 7
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1404-1405. nia better in the nonindustrialized societies?
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A. Prediction of the Course of Schizophrenia
I. Patient Attributes

1. Outcome and Prediction of Outcome in


Schizophrenia: Results from the Literature and
from Two Personal Studies
H. J. Moller, W. Schmid-Bode, H. U. Wittchen, and D. v. Zerssen

Short Review of the Literature


A large number of studies investigating the in general, schizophrenia has a poor out-
outcome of schizophrenia have been car- come in less than 50% of the patients. This
ried out. These studies have provided many was not only demonstrated by short-term
hypotheses about the course of the illness, follow-up studies (e.g., Strauss and Car-
especially the characteristics of and the pre- penter, 1974; Astrachan et al. 1974; World
diction of the outcome. However, the find- Health Organization 1979) but also in long-
ings of the earlier studies have been ques- term follow-up studies covering 5 - 20 years
tioned because of severe methodological and more (e.g., Bleuler, 1972; Strauss and
deficiencies. In most of these studies, ret- Carpenter, 1977; Huber, Gross and Schutt-
rospective evaluation techniques or insuffi- ler, 1979; Achte, 1980; Watt, Karz, and
ciently standardized instruments were em- Schepherd, 1983). Comparing the results of
ployed and many have introduced signifi- older and newer studies, there is some evi-
cant bias. Some more recent studies, how- dence from follow-up studies that the better
ever, have avoided such methodological outcome of schizophrenia in the recent de-
problems by studying patients prospective- cades is due to modern biological treatment
ly. Unfortunately, these excellent studies methods, but also some factors, e.g., insti-
have evaluated patients only over short pe- tutional changes, must be taken into consid-
riods of time, generally from 1 to 2 years eration (Hogarty, 1977).
(e.g., Schooler, Goldberg, Boothe, and Based on the results of studies on long-
Cole, 1967; Astrachan, Brauer, Harrow, term treatment with neuroleptics (Davis,
and Schwartz, 1974; Hogarty, Goldberg, Schaffer, Killian, Kuard, and Chan, 1980),
Schooler, and Ullrich, 1974; Strauss and it can be concluded that this therapeutic ap-
Carpenter, 1974; Wittenborn, McDonald, proach is effective in preventing relapses of
and Maurer, 1977; World Health Organiza- schizophrenic illness in a high percentage of
tion, 1979). Only the 5-yearfollow-up study schizophrenic patients. Hitherto, it has
of patients in the International Pilot Study been rather uncertain whether the global
of Schizophrenia (IPSS) covers a longer pe- outcome concerning psychopathology and
riod of time. Thus far, data from this 5-year social adjustment after many years is better
follow-up study have only been published in those patients who took neuroleptic
by the Washington Research Center of the drugs than in those who refused to do so.
IPSS (Hawk, Carpenter, and Strauss, 1975; This is especially true for treatment periods
Strauss and Carpenter, 1977). longer than 3 years because there is no con-
Although there are many discrepancies trolled study on this topic. Another pro-
between the results of different follow-up blem of neuroleptic long-term treatment is
studies - these discrepancies are caused, that a~out 20% - 30% of the patients seem
among other things, by differences in sam- to be nonresponders.
pling, diagnostic process, assessment of The knowledge on the effect of psycho-
variables, length of follow-up period - therapeutical strategies in schizophrenia is
some findings have been replicated in many inconclusive up to now. The reported re-
of them. Very important is the result that, sults of controlled studies concerning psy-
12 H. J. Moller et al.
choanalytical individual therapy, for exam- sonality, or adjustment and length of epi-
ple, seem to indicate that a significant effect sode prior to assessment are known as pre-
on outcome variables was not measurable dictors of poor outcome. Besides this sub-
(Cancro, Fox, and Shapiro, 1978; Feinsil- stantial agreement on certain in prognostic
ver and Gunderson, 1972; Grinspoon, criteria, some findings remain contradicto-
Ewalt, and Shader, 1968; May, Tuma, and ry, such as the prognostic implications of
Dixon, 1977; Mosher and Keith, 1979). certain psychopathological symptoms.
The recent results of family intervention In general, the percentage of outcome
strategies, based on the concept of high ex- variance explained by a single one of these
pressed emotion (Vaughn and Leff 1976), predictors was rather low. Therefore, in re-
seem to be more hopeful (see Anderson, cent studies, combinations of predictors
Falloon, and Leff et aI., this volume). High were analyzed by multivariate methods to
expressed emotion of close relatives was increase the percentage of explained out-
also described as an important predictor of come variance (Strauss and Carpenter,
schizophrenic relapses (Chap. 2). 1977; WHO, 1979). However, such findings
There is a long tradition concerning the of multivariate analyses must be considered
differentiation of schizophrenia with good critically because the multivariate method
and poor outcome. In this context, the diag- optimizes the result concerning the specific
nostic concepts of schizophreniform psy- sample. Consequently, the practical rele-
chosis, reactive psychosis, atypical psy- vance has to be proven by cross validation.
chosis, and schizoaffective psychosis - all Replication studies concerning the results
describing psychoses with a comparatively of such multivariate analyses, however,
good outcome - have to be mentioned were usually not performed.
(Langfeld, 1957; Eitinger, Laane, and Another approach to improve the predic-
Langfeld, 1958; Wellner and Stromgren tion of outcome is the simple combination
1958; Vaillant, 1962; Stephens and Astrup, of relevant predictors, either according to
1965; Achte, 1967; Stephens, 1970; the literature or identified by one's own ana-
Crougan, WeIner, and Robins, 1974; Hawk lyses. Such combination scores should also
et aI., 1975; Tsuang, Woolson, and Fle- prove their predictive power in cross-vali-
ming, 1979). Besides psychopathological dation studies. However, this attempt if
and anamnestic characteristics defining performed at all, was successful only in a
these subtypes, numerous other psycho- few studies (Kokes, Strauss, and Klorman,
pathological, sociodemographic, and 1977; Strauss and Carpenter, 1974). The
anamnestic data have been described as total score of such a prognostic scale should
relevant concerning prognosis (Renton, guarantee a better prediction than any sin-
Affleck, Carstairs, and Forrest, 1965; gle predictive item, a presumption that does
Achte, 1967; Strauss and Carpenter, 1974; not seem to be fulfilled by some of these
Tsuang and Winokur, 1974; Gunderson, scales (Moller et aI., 1984 a, b, c). Several
Carpenter, and Strauss, 1975; Hawk et aI., prognostic scales for schizophrenic patients
1975; Pokorny, Thornby, Kaplan, and Bau, have been described in the literature
1976; Goldberg, Schooler, Hogarty, and (Kokes et aI., 1977). Some of them consist
Roper, 1977; Hargreaves, Glick, Drues, only of data on premorbid adjustment -
Showsrack, and Geigenbaum, 1977; such as the Phillips scale (Phillips, 1966) -
Strauss and Carpenter, 1977; Wittenborn some others focus more on psychopatholog-
et aI., 1977; Bland, Parker, and Om, 1978; ical items - such as the Vaillant scale (Vail-
Huber et al., 1979; World Health Organiza- lant, 1962) or the Stephens scale (Stephens,
tion, 1979). Only some of these predictors 1970). The broadest approach was realized
could be replicated by different research by the Strauss-Carpenter prognostic scale,
groups, e.g., lower age at onset, insidious a multidimensionaL approach combining
onset, no precipitating factors, affective aspects of psychopathology, social adjust-
blunting, disturbances of premorbid per- ment, and history of illness.
Outcome and Prediction of Outcome in Schizophrenia 13

Results of Own Follow-up Studies on Schizophrenia


Outcome and Predictors, First Sample

Our first study was a 5- to 6-year follow-up viously been admitted to a psychiatric hospi-
on about 100 patients who had been treated tal before entering the Max Planck Institute
as inpatients in the Max Planck Institute of (index admission). The sample was almost
Psychiatry (Moller et al. 1981 a, b, 1982 a, equally divided between men (49%) and
b). The study was performed using standard- women (51%). Sixty-six patients (82%)
ized assessment procedures, among them were 40 years old or younger, and only one
the Inpatient Multidimensional Psychiatric patient was over age 60. Only 22% were
Scale (IMPS) (Lorr, 1974) and the clinical married. Treatment consisted of neurolep-
self-rating scales (von Zerssen, 1976) to de- tics (mostly haloperidol, in individualized
scribe the psychopathological state and the but not high dosages), supportive psycho-
Global Assessment Scale (GAS) (Spitzer, therapy, and sociotherapy. Hospitalization
Endicott, and Fleiss, 1976) for describing was not longer than 3 months for 92% ofthe
the global outcome at follow-up. patients with only 8% staying for more than
At discharge 5 years earlier, the clinical 4 months. Usually 1-2 weeks before dis-
diagnosis was based on the leD classifica- charge, the oral neuroleptic medication was
tion. Of all the patients, 77% met the leD changed to an intramuscular depot neuro-
description for schizophrenia (leD 295; pa- leptic. The sample seems comparable to the
tients with schizo affective psychoses: leD schizophrenic population of university clin-
295.7 were excluded from this study) and ics, but not to that of county hospitals where
23% the leD descriptions for other types chronic patients are overrepresented. It
of paranoid psychoses (leD 297, 298.2, also appears comparable to the IPSS sam-
298.3,298.9). At follow-up, seven patients ple, which excluded chronic patients (with
had died, five of them by suicide. Sufficient psychotic symptoms of more than 2 years
follow-up data for the statistical analyses duration in the 5 years before index admis-
could be obtained from 81 patients, for sion or hospitalized more than 3 years).
three of them only by relatives. At follow-up, 44% of the patients showed
This sample (n = 81) included patients serious psychopathological symptoms and/
with their first lifetime episode (55%) or re- or disturbances of social adjustment, indi-
turn of the disorder at index admission. cated by a score below 50 on the GAS; 31 %
Sixty percent of the patients had never pre- were below a GAS score of 40, which means

Table 1. Level of Functioning (GAS Score) at Follow-up

Information from
Patients Relatives
Level of functioning No. % No. %
100-91 No symptoms 8 10 5 10
90-81 Transient symptoms 8 10 0 0
80-71 Minimal symptoms 4 5 5 10
70-61 Some mild symptoms 14 18 11 23
60-51 Moderatesymptoms 8 10 1 3
50-41 Any serious symptomatology 10 13 6 13
40-31 Majorimpairment 15 19 11 24
30- 21 Unable to function 9 12 8 17
20-11 Needs some supervision 0 0 0 0
10-1 Needs constant supervision 0 0 0 0
Not classifiable 2 3 0 0
Total 78 100 47 100
14 H. J. Moller et al.
according to the GAS definition that hospi-
talization would be expected if the patient
was not already hospitalized. During the
follow-up period, 34% of the patients were
unable to work for more than 1 year; 58%
had to be readmitted to a psychiatric hospi-
tal, 10% for more than 1 year. At follow-
up, 16% were living in a nursing home and
6% were psychiatric inpatients (Table 1).
Correlation analyses between the GAS
score and other outcome criteria demon-
strated that the GAS score best reflects the
general outcome (Table 2). Therefore, it
0\
V)
was chosen as the main criterion for the
o analysis of predictors. Among approxima-
I tely 40 potential predictor variables tested
in a product moment correlation analysis, a
O","N\O ,....;
number of variables proved to be statistical-
000"'""'"
""';000
V)
o
ly significant (P < 0.05) predictors of global
outcome (Table 3). The best predictors
(r > 0.35) were: duration of occupational
O<'l","NN
disintegration (inability to work, unemploy-
o \0\0 \0 V)
""';0000 ment) during the 5 years preceding index
admission, impairment of working ability in
the year before index admission, personali-
00\0\<'lV)""';
ty change before index admission, poor psy-
or-\Or-V)V)
""';00000 chopathological state on discharge, and the
self-rating factor of paranoid tendencies at
discharge. High scores on these variables
000","0\000\<'l
were correlated with a poor global out-
o \0 V) r- 00 <'l V)
""';000000 come. Besides these variables, some others
correlated significantly with the outcome
criterion, but mostly the percentage of ex-
ONr-r-Oo\\O""'; \0
plained variance was below 10%.
Or-<'lNV)V)N","
""';0000000
V)
o Most of the predictors found in our study
have already been mentioned in the litera-
ture dealing with the prognosis of schizo-
phrenia. Among those variables that
proved to be of greatest prognostic signifi-
cance in our own study, occupational dis-
integration (employment status) before in-
dex admission was a strong predictor in stu-
dies by Strauss and Carpenter (1974,1977).
The prognostic value of the psychopatho-
logical state at discharge was emphasized by
Renton et al. (1965), Affleck, Burns, and
Forrest (1976), and Wittenborn et al.
(1977). A personality change, especially in
the sense of a lack of emotion, is another
predictor that has been described by many
authors (Vaillant, 1964; Lindelius, 1970;
Stephens, 1970; WHO, 1979).
Analyses of correlations between the
predictor variables and other outcome
Outcome and Prediction of Outcome in Schizophrenia 15
Table 3. Predictors of Global Outcome (GAS) (n = 74-78; for Self-Rating Factors, n = 45-50)
Correlation
Predictors of global outcome (GAS) coefficient
(-) Higher socioeconomic status of the parents .25
(-) Premorbid working dysfunction .27
(+) More advanced age at first manifestation .28
(+) More advanced age at first hospitalization .23
(+) Precipitating factors before first manifestation .28
(-) Duration of psychiatric hospitalization (5 years before index admission) .27
(-) Duration of occupational disintegration (5 years before index admission) .38
(+) Lasting heterosexual relationship .28
(- ) Impairment of working ability (1 year before index admission) .39
(-) Personality change (1 year before index admission) .42
(-) Diagnosis of schizophrenia .25
(- ) Poor psychopathological state at discharge .35
(-) IMPS superfactor of organic syndrome * at discharge .30
(- ) IMPS superfactor of depressive-apathetic syndrome" at discharge .24
(+) Ratio of amelioration of the IMPS superfactor of psychotic excitement .28
(-) Self-rating factor of paranoid tendencies at discharge .39
(+ ) Ratio of amelioration of the self-rating factor of paranoid tendencies .40
( + ) = good prognosis; ( - ) = poor prognosis
, IMPS factor "retardation and apathy" + IMPS factor "disorientation";
** IMPS factor "anxious depression" + IMPS factor "retardation and apathy" + IMPS factor "im-
paired functioning"

criteria revealed that the prognostic signifi- psychoses (leD 297, 298.3). In this inves-
cance of one variable for the GAS score did tigation, the follow-up period was 5-8
not necessarily apply to other outcome cri- years.
teria (Table 4). Likewise, a variable that is At follow-up, two patients had com-
a good predictor for one outcome criterion mitted suicide. Sufficient information for
may not be predictive for the outcome on the statistical analyses could be obtained
the GAS. The inclusion of variables that are from 46 patients: 32% of them had never
predictive for other outcome criteria, but been admitted to a psychiatric hospital
not for the GAS, expands the number of prior to their treatment in the Max Planck
predictors. Institute (index admission); 59% of the pa-
tients were male, 41 % female; 83% were 40
years old or younger. Only 24% were mar-
Outcome and Predictors, Second Sample
ried.
Using partially the same assessment The outcome results are rather similar to
procedures, a second follow-up study the first sample; concerning the longitudi-
(Schmid-Bode and Moller, in preparation) nal criteria, they were somewhat worse,
on patients of the same diagnostic group perhaps due to the longer follow-up period.
was performed to replicate the findings con- Of the patients, 33% showed serious psy-
cerning outcome and predictors, especially chopathological symptoms and/or disturb-
the findings on prognostic scales (see p. 17) ances of social adjustment (GAS score be-
on the one hand and to compare the out- low 50); 26% were rated on the GAS below
come results with affective psychoses and 40, indicating that they needed hospital
schizoaffective psychoses on the other (see treatment; 49% of the patients were unable
p.19). This sample included 61 patients who to work for more than 1 year during the fol-
had been treated in the Max Planck Insti- low-up period; 81 % had to be readmitted to
tute of Psychiatry. Most of the patients (55) a psychiatric hospital; and: 30% were treat-
were diagnosed as schizophrenics (without ed for more than 1 year as psychiatric in-
schizoaffective psychoses) and only six as patients during 5 years after index treat-
suffering from similar types of paranoid ment. At follow-up, 26% were living in a
16 H. J. MOller et al.
Table 4. Product-Moment Correlations of the Most Important Predictors (Correlations with the G AS-
Score r > 0.35). Sample I (n = 74-78); Sample II = Replication Sample (n = 43-46)

Sample I Impair- Global Person- Impair- Para- Depres- Dura- Dura-


ment of psycho- ality mentof noid- sive- tion of tionof
level of patho- change work hallucin- apathet- occupa- psychi-
function-logical ability atory ic tional atric
ing state syn- syn- disinte- hospi-
(GAS) drome drome gration taliza-
(IMPS) (IMPS) tion
Duration of occupational
disintegration (5 years
beforelA) 0.38** 0.32** 0049*** 0048*** 0.28* 0.32* 0047*** 0.52***
Impairment of work
ability(lyearbeforeIA) 0.39** 0.34** 0046*** 0.30* 0.23* 0.23* 0.17 0.24
Personality change
(1 year before IA) 0042*** 0042*** 0.59*** 0040** 0.27* 0.19 0.29* 0.15
Psychopathological
state at discharge 0.35** 0047*** 0.19 0.22 0.26* 0.04 0.11 0.15

Sample II Impair- Global Person- Impair- Para- Depres- Dura- Dura-


ment of psycho- ality mentof noid- sive- tion of tionof
level of patho- change work hallucin- apathet- occupa- psychi-
function- logical ability atory syn- tional atric
ing state syn- drome desinte- hospi-
(GAS) drome gration taliza-
(IMPS) (IMPS) tion
Manic or depressive
component (first
manifestation) -0.38* -0.23 -0.26 -0.08 -0.26 -0.25 -0.06 -0.13
Lasting hetero-
sexual relation-
ship (IA) -0043* -0040* -0042* -0.32* 0.34 * -0.29 -0.22 -0040*
Duration of occu-
pational disinte-
gration (5 years
beforelA) 0.40* 0.38 0.52** 0048** 0.20 0.44** 0.33* 0.56***
Psychopatholog-
ical state at dis-
charge 0.36* 0046** 0049** 0.50** 0.12 0043* 0.44** 0.27
* = P < 0.05; ** = P < 0.01; *** = P < 0.001; IA = index admission

nursing home or were psychiatric inpa- sexual relationship. Some others were not
tients. replicated as predictors concerning the
As to the predictors of outcome, some GAS score, e.g., age at onset of the illness
findings could be replicated. Of special in- and age at first psychiatric hospitalization,
terest is that the duration of professional self-rating of paranoid tendencies at dis-
disintegration during the 5 years before in- charge, personality change before index ad-
dex admission and the psychopathological mission, and depressive-apathetic syn-
state at discharge again were found among drome at discharge. Thus, the known fact
the best predictors (Table 3). Also, some that results of predictor analyses depend in-
other characteristics again could prove their tensively on the specific characteristics of
predictive value, such as a lasting hetero- the sample becomes obvious.
Outcome and Prediction of Outcome in Schizophrenia 17
Optimizing the Predictive Possibilities by Kokes et al. (1977), apart from the fact that
Prognostic Scales we used an inverse scoring for the Strauss-
Carpenter scale. The data for these scales
To increase the outcome variance explain- had to be gathered from the records so that
ed by single predictors and to make the pre- in this respect the study is complicated by
diction more stable concerning different the typical problems of retrospective ap-
samples and different outcome criteria, proaches. Fortunately, the records of the
prognostic scales were applied (Moller, Psychiatric Department of the Max Planck
Schad, and Zerssen, 1984a, 1984b). Four Institute of Psychiatry (MPIP) are rather
scales communicated in the literature were well structured and informative so that in
tested concerning their predictive validity: most cases the necessary data were availa-
1. The Gittelman-Klein scale of prem- ble. In this context, it has to be mentioned
orbid adjustment (Gittelman-Klein and that some of these scales, such as the Phil-
Klein, 1969) lips scale, were developed with the special
2. The Phillips scale of premorbid adjust- aim of making it possible to obtain an evalu-
ment (Phillips, 1966) in the short version ation on the basis of data from case records.
of Harris (Harris, 1975) To avoid a potential bias, the evaluation of
3. The Goldstein scale of pre morbid adjust- the records was made by a psychiatrist who
ment (Rodnick and Goldstein, 1974) was not informed about the outcome data
4. The Strauss-Carpenter prognostic scale of the patients.
(Strauss and Carpenter, 1974) In addition, four new prognostic scores
All these scales were used in the version were developed and tested concerning their
published in the appendix of the review by predictive validity. Based on the results of

Table 5. Items of the Self-Constructed Prognostic Scores

Score 1 Score 2 Score 3 Score 4


Premorbid working dysfunction x
No precipitating factors before first manifestation x x x
Younger age at first hospitalization x
No signs of manic depressive disorder at first
manifestation x
Duration of occupational disintegration
(5 years before index admission) x x x
Duration of psychiatric hospitalization
(5 years before index admission) x
No lasting partnership at index admission x
Impairment of working performance
(during the year after index admission x x x
Residual syndrome (personality change)
prior to index admission x
Poor psychopathological state at discharge x x x
IMPS superfactors
"Organic syndrome" at discharge" x
"Depressive, phobic-compulsive
syndrome"*" at discharge (- ) x
IMPS factors
"Disorientation" at admission ( - ) x
"Obsessional-phobic" at admission ( - ) x
"Retardation and apathy" at discharge x
"Paranoid projection" at discharge x
"Motor disturbances" at discharge x
" IMPS factor "disorientation" + IMPS factor "retardation and apathy";
*" IMPS factor "anxious depression" + IMPS factor "obsessional phobic"
(-) = the value (10% of the theoretical score = 1,20% = 2, etc.) must be subtracted from the total
score
18 H. J. Moller et a1.
univariate and multivariate analyses of pre- 12 IMPS syndrome scores at admission and
dictors concerning the first sample of pa- discharge. It was constructed by the combi-
tients (Moller et aI., 1981b, 1982a, 1982b), nation of the five best predictors concerning
these prognostic scores (Moller, Schmid- the GAS score: total score of "disorienta-
Bode, and Zerssen, 1984c) were created by tion" and "obsessional phobia" at admis-
combinations of five to eight unweighted sion, total score of "retardation and apa-
predictors (Table 5). The first one contain- thy," "paranoid projection," and "motor
ed seven variables, the predictive signifi- disturbances" at discharge. This was the
cance of which was proven by univariate only scale that consisted of psychopatho-
analyses. They all correlated relatively logical data alone, whereas the other scores
highly (r > 0.35) with the GAS score and/or contained psychopathological data as well
they correlated significantly with several as sociodemographic data, data on social
other outcome criteria. The second score adjustment, and illness-related informa-
consisted of five variables, which had emer- tion.
ged from stepwise mUltiple regression anal-
ysis as the best predictor combination for Considering the main outcome criterion,
the GAS score. Score 4 was also based on the GAS score, the Strauss-Carpenter scale
the results of stepwise multiple regression obtained the best results (r = 0.43) in the
analyses. It contained all those predictor first sample. The predictive value of the
variables which had repeatedly appeared Gittelman-Klein scale and of the Phillips
among the combination of the five best pre- scale were somewhat lower (about
dictors concerning the different outcome r = 0.30); the Goldstein scale failed to prove
criteria. The third score was based on the a significant correlation with the global lev-
stepwise multiple regression analysis of the el of functioning (Table 6).

Table 6. Product-Moment Correlations of Prognostic Scales and Outcome Criteria

Variables Impair- Global Person- Impair- Para- Depres- Dura- Dura-


mentof psycho- ality mentof noid- sive- tionof tionof
level of patho- change work hallucin- apathet- occupa- psychi-
function- logical ability atory ic- tional atric
ing state syn- syn- desinte- hospi-
(GAS) drome drome gration taliza-
(IMPS) (IMPS) tion
Gittelmann- 0.28* 0.20 0.50*** 0.30* 0.21 0.36** 0.19 0.34*
Klein scale 0.28 0.28 0.35* 0.13 0.15 0.37* 0.26 0.34*
Goldstein -0.19 -0.07 -0.38** -0.31 -0.14 -0.38* -0.22 -0.31 *
scale -0.24 -0.33 -0.39* -0.12 0.19 -0.35 -0.29 -0.31
Phillips 0.29* 0.22 0.43*** 0.36** 0.19 0.38*** 0.28* 0.46***
scale 0.46** 0.48** 0.48** 0.22 0.12 0.48*** 0.34* 0.36*
Strauss-Car- 0.43*** 0.42*** 0.54*** 0.37** 0.38** 0.39*** 0.32** 0.49***
penter scale 0.41** 0.44** 0.52*** 0.40** 0.21 0.36* 0.40** 0.46**
Score 1 0.53*** 0.51*** 0.55*** 0.45** 0.36* 0.28 0.32* 0.36*
0.44* 0.50* 0.60* 0.49* 0.08 0.45* 0.47* 0.49*
Score 2 0.56*** 0.54*** 0.64*** 0.54*** 0.37** 0.29* 0.38** 0.52***
0.43* 0.49* 0.56* 0.43* 0.07 0.43* 0.39* 0.42*
Score 3 0.32* 0.27* 0.35** 0.39*** 0.33** 0.27* 0.24* 0.27*
0.21 0.30* 0.26 0.22 -0.08 0.14 0.23 0.36*
Score 4 0.62*** 0.55*** 0.72*** 0.76*** 0.39** 0.38* 0.53*** 0.51***
0.43* 0.57* 0.59* 0.54* 0.09 0.46* 0.49* 0.47*
Correlations above: sample I (n = 55-57); correlations below: sample II (n = 35-46).
* P<0.05 ** P < 0.01 *** P < 0.001
Outcome and Prediction of Outcome in Schizophrenia 19
The Strauss-Carpenter scale had also the In comparison with the newly developed
highest predictive power from the view- scores, the prognostic scales from the litera-
point of the magnitude and the number of ture obtained slightly less favorable results
significant correlations with the other out- (Table 6) also in the replication sample. In
come criteria. The scale reached prognostic general, however, they reached the same
significance for all eight outcome criteria predictive level as in the former sample.
within a range of r = 0.32 to r = 0.54. Also, Again, the Strauss-Carpenter scale proved
the highest correlation with an outcome cri- to have the highest prognostic value, fol-
terion was achieved by the Strauss-Carpen- lowed closely by the Phillips scale.
ter scale: the correlation with personality It can be summarized that the four prog-
change (r = 0.54). In comparison to this nostic scales described in the literature as
scale, the Gittelman-Klein scale proved well as three of the newly constructed prog-
only significant correlations with five, the nostic scores gave better results in general
Phillips scale only with six and the Gold- than any single predictive variable. The cor-
stein scale only with three outcome criteria. relations with different outcome criteria
The newly developed scores showed bet- were mostly comparatively close, e.g., the
ter results in the first sample (Table 6). Strauss-Carpenter scale was able to explain
There was a significant and rather close cor- 16% of outcome variance. It seems that a
relation with nearly all outcome criteria. multidimensional approach, taking into ac-
Concerning the global level of functioning, count many different aspects, ranging from
score 4 obtained the best results (r = 0.62), social functioning to illness-related varia-
closely followed by scores 1 and 2. Score 3, bles, reaches a better prognostic value than
which consisted only of psychopathological approaches that regard less complex con-
data, was less significant. Considering the cepts, such as premorbid adjustment orpsy-
other outcome criteria, scores 1, 2, and 4 chopathological syndromes. Such scales
also seemed to be rather equivalent in their may have a comparatively high predictive
potential predictive power. They showed value if certain dimensions and aspects are
rather close correlations to nearly all out- regarded. However, even by adding more
come criteria. Only score 3 has a lower, but and more items to a prognostic scale, a cer-
mostly significant relationship to the other tain maximum can usually not be exceeded.
outcome criteria. Perhaps a higher number of items can guar-
antee a better stability of the predictive
It could be expected that the newly devel- power in different samples.
oped scales would show better results than
the older prognostic scales in the original
sample of patients, in which they have been Prognosis of Schizophrenia Compared to
Other Endogenous Psychoses and to the
developed. To test their predictive value
more realistically, the data of the cross-vali- Average Population
dation study on the second sample have to The outcome of schizophrenic or similar
be considered (Table 6). Scores 1, 2, and 4 psychoses (second sample) was compared
reached highly significant substantial cor- to the outcome of affective or schizoaffec-
relations to almost all outcome criteria. tive psychoses and to controls from the
Score 3 largely failed to prove predictive average population.
significance. There were only significant Twenty-two former inpatients with schi-
correlations between score 3 and the out- zoaffective psychoses (ICD 295.7) (Zaudig
come criteria "global psychopathological and Vogl, in prep.) and 35 former inpa-
state" and "duration of psychiatric hospi- tients with affective psychoses (ICD 296)
talization". Scores 1, 2, and 4 were of a bet- (Cording-T6mmel, in preparation) were
ter predictive value considering the magni- also followed-up 5-8 years after their hospi-
tude and frequency of significant correla- tal treatment at the MPIP. The mean age
tions with the outcome criteria than the best was higher for patients with affective psy-
single predictors. The superiority of score 4 choses (44 years at the time of follow-up)
which had been found in the original sample than for the patients with schizophrenia (37
was not replicable. years) and schizoaffective psychoses (38
20 H. J. Moller et al.
50%

40

30

20

10

Fig. 1. Global level of func-


tioning (GAS) 5-8 years after
discharge.
10 20 30 40 50 60 70 80 90 100 GAS
o Schizophrenia
li'I Affective psychosis
• Schizoaffective psychosis

years). There were more female patients patients with affective psychoses, and 33%
among affective psychoses (57%) and schizo- of schizophrenics. In the worst group
affective psychoses (68%) (schizophre- ("completely unable to work or help with
nia: 41 % females). In addition, the schizo- the housekeeping"), only schizophrenic pa-
phrenic sample was compared concerning tients (24%) were found. The duration of
social adjustment to 46 nonpatients occupational disintegration during the fol-
matched for sex, age, and marital status low-up period exhibited a similar tendency:
from a random sample of 499 persons of the the schizophrenics had the longest duration
general population who were assessed by of inability to work.
the same standardized method. To measure These results might be partially biased by
social adjustment, a modified version of the the discrepancies of sociodemographic vari-
social interview schedule (SIS) (Clare and ables mentioned above. In this respect, the
Carins, 1978; Faltermaier, 1982) was ap- comparison of SIS data between patients
plied. and matched controls attracts more confi-
At follow-up, 77% of the patients with dence. Furthermore, the structured SIS al-
affective psychoses were married compared lows a more detailed view on social adjust-
to 17% of schizophrenic and 27% of schizo- ment (Figure 3). The objective conditions
affective patients. The global level of func- of occupation (for the 50% of schizophrenic
tioning as measured by the GAS also show- patients who were still working or studying)
ed marked differences between the diagnos- and the opportunities for social contacts
tic groups. The schizophrenic patients and leisure activities were not markedly dif-
were, on an average rated in the lower half ferent for schizophrenic patients and
of the 1oo-point GAS score range, whereas matched controls. Regarding their social
patients with affective of schizo affective management, however, significantly more
psychoses were more frequently repres- schizophrenic patients had marked or severe
ented in the upper range of scores (Fig- problems in occupation, social contacts,
ure 1). and leisure activities. Subjective dissatisfac-
Impairment of working performance in- tion was also more frequently expressed by
cluding study and housekeeping during the schizophrenic patients, but here the dif-
last year of the follow-up period can be seen ferences were not as marked. This discrep-
from Figure 2. No impairment was shown ancy between the ratings on management
by 95% of schizo affective patients, 71% of on the one side and the ratings on satisfac-
Outcome and Prediction of Outcome in Schizophrenia 21

1::%1
80

70

60

50

40

30

20
Fig. 2. Impairment of working 10
performance 5-8 years after dis-
charge.
o ~~~ ______ ~~ ____ ~~ ____ ~~ ______ L L_ __ _ _

No impairment Moderate impairment Inability to work


Slight impairment Serious impairment
o Schizophrenia
G Affective psychosis
• Schizoaffective psychosis

Social contacts and


%
Occupation leisure activities
60
50
4fJ
Difficult
objective 30
conditions 20
10

Social Leisure
Occupation contacts activities
%
60
50
Problems .0
in social 30
management
20
10

Social Leisure
Occupation contacts activities
%
60
50

Fig. 3. Percentage of subjects with 4fJ


Dissatisfaction 30
marked or severe difficulties in
objective conditions, social man- 20
agement, and subjective satisfac- 10
tion according to the SIS.

• Patients (n = 43, occupation: n = 23)


o Controls (n = 46, occupation: n = 40)
22 H. J. Moller et al.
tion on the other side might be explained affective psychoses. The outcome of schizo-
partially by affective blunting and schizoid affective psychoses seems to be similar to
personality traits. that of affective psychoses, which supports
In contrast to the schizophrenic patients, the hypothesis that this diagnostic group
the patients with schizo affective psychoses should be classified separately or as a sub-
or affective psychoses were not significantly group of the affective psychoses rather than
different from the controls concerning the as a subgroup of schizophrenic psychoses, a
SIS dimensions mentioned above. hypothesis based on the results of other fol-
It can be concluded that patients with low-up studies as well as on genetic findings
schizophrenic psychoses have a poorer out- (Tsuang et al., 1979; Angst, Felder, and
come than patients with affective or schizo- Lohmeyer, 1980).

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31,37-42. Gittelman-Klein, R., and Klein, D. F. (1969).
Bland, R. C., Parker, J. H., and Om, H. (1978). Premorbid asocial adjustment and prognosis in
Prognostic predictors and outcome. Archives schizophrenia. Journal of Psychiatric Re-
of General Psychiatry, 35, 72-77. search, 7, 35-53.
Bleuler, M. (1972). Die schizophrenen Geistes- Goldberg, S. C., Schooler, N. R., Hogarty, G.
storungen im Lichte langjiihriger Kranken- und E., and Roper, M. (1977). Prediction ofrelapse
Familiengeschichten. Stuttgart: Thieme. in schizophrenic out-patients treated by drug
Cancro, R., Fox, N., and Shapiro, L. E. (1978). and sociotherapy. Archives of General Psy-
Behandlungstechniken bei Schizophrenie. chiatry, 34, 171-184.
Munchen: Reinhardt. Grinspoon, L., Ewalt, J. R., and Shader, R. J.
Clare, A. W., and Cairns, V. E. (1978). Design, (1968). Psychotherapy and Pharmacotherapy
development and use of a standardized inter- in chronic schizophrenia. American Journal of
view to assess social maladjustment and dys- Psychiatry, 124, 1645-1651.
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Medicine, 8, 589-604. Strauss, J. S. (1975). Borderline and schizo-
Croughan, J. L., Weiner, A., and Robins, E. phrenic patients: A comparative study. Ameri-
(1974). The group of schizoaffective and relat- can Journal of Psychiatry, 132, 1257-1264.
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General Psychiatry, 37: 632-637. Short vs. long hospitalisation: VI. Two-year
Davis, J. M., Schaffer, C. B., Killian, G. A., follow-up results for schizophrenics. Archives
Kuard, C., and Chan, C. (1980). Important of General Psychiatry, 34, 305-311.
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Outcome and Prediction of Outcome in Schizophrenia 23
the Phillips rating scale of premorbid adjust- Moller, H. J., Zerssen, D. v., Werner-Eilert, K.,
ment in schizophrenia. Journal of Abnormal and Wiischner-Stockheim, M. (1982b). Out-
Psychology, 84,129-137. come in schizophrenic and similar paranoid
Hawk, A. B., Carpenter, W. T., and Strauss, J. psychoses. Schizophrenia Bulletin, 8, 99-108.
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come in schizophrenia: A report from the In- (1984a). StOrungen der pramorbiden sozialen
ternational Pilot Study of Schizophrenia. Ar- Adaptation als Priidiktor fUr die Fiinfjahres-
chives of General Psychiatry, 32, 343-347. prognose schizophrener Psychosen. Nerven-
Hogarty, G. E. (1977). Treatment and the course arzt, 55, 358-364.
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587-599. (1984b). Strauss-Carpenter-Skala: Uberprii-
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R., and Ullrich, R. F. (1974). Drug and socio- res-"Outcome" schizophrener Patienten. Eu-
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(1977). Premorbid adjustment in schizophre- Mosher, L. R., Keith, S. J. (1979). Research on
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Acta Psychiatrica Scandinavica, (Suppl. 216). and Forrest, A. D. (1965). A follow-up of schi-
May, P. R. A., Tuma, A. H., and Dixon, W. J. zophrenic patients in Edinburgh. Acta Psy-
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Mental Diseases, 165,231-239. mothering function in acute schizophrenic
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24 H. J. Moller et al.
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II. Family Attributes
2. An Introduction to EE Measurement
and Research
J. M. Hooley

Introduction
Expressed emotion (EE) is currently one of provided good evidence that the construct
the most important measures of family of EE is both valid and can be measured
functioning available to clinicians and re- reliably. Moreover, not only do familial
searchers working with schizophrenic pa- levels of EE predict relapse in schizophre-
tients. Based as it is on the number of criti- nic patients, but EE also appears to have
cal comments and level of emotional overin- some predictive validity for other psy-
volvement spontaneously expressed by a chiatric populations, specifically the depres-
relative over the course of the Camberwell sed. This introductory chapter will discuss
Family Interview (CFI) , the EE rating is the development of the EE construct and its
considered to reflect the attitude of the re- measurement and focus on some of the re-
lative toward the psychiatrically ill family search which has made an important contri-
member. bution to our current understanding of this
Research conducted in recent years has valuable concept.

An Historical Perspective
The initial stimulus for the development of high levels of contact with their families.
the EE construct came originally from work That spending a lot of time with close re-
begun in England. Working with more than latives might not necessarily be beneficial to
200 discharged male psychiatric patients, schizophrenics was a rather unusual find-
most of whom had a diagnosis of schizophre- ing, and in subsequent research Brown
nia, Brown and his collegues (Brown, 1959; (Brown, Monck, Carstairs, and Wing,
Brown, Carstairs, and Topping, 1958) ob- 1962) attempted to document more preci-
served that the type of living group to which sely those aspects of living situations
patients were discharged seemed to be as- having most impact on patient outcome. In
sociated with how well or how poorly they a later study, which again used male schizo-
fared upon return to the community. Of phrenics, Brown employed a prospective
particular interest was the finding that pa- design and, in addition, interviewed the key
tients who returned to live in lodgings or female relative of each patient on three dif-
with siblings were more psychiatrically ferent occasions. Levels of "emotion ex-
healthy over the course of the subsequent pressed," "hostility," and "dominance"
year than patients who were discharged into were assessed for patients and relatives, al-
the parental or matrimonial home. Inter- though later analyses revealed only the rat-
estingly, it was also noted that the amount ings made for relatives to have any predic-
of time patients spent in contact with their tive utility. Briefly, the results showed that
relatives was another important factor relat- patients who returned to homes high in hos-
ed to outcome; patients who had only limit- tility or EE (high emotional involvement
ed contact with their relatives were less like- homes) were more likely to suffer a psychia-
ly to suffer a relapse than patients who had tric relapse over the course of a 1-year fol-
26 J. M. Hooley
low-up than patients who returned to live in assessments made and establishing reliable
low emotional involvement homes. techniques of EE measurement (Brown
This confirmation of the original finding and Rutter, 1966; Rutter and Brown,
was encouraging and, over subsequent 1966). The result was the development of
years, Brown and his co-workers began to the Camberwell Family Interview, describ-
focus attention on improving the interview ed below.

Measuring EE
Family levels of EE are assessed by means that's probably because I'm a rather intoler-
of the CFI, a nonschedule, standardized in- ant person." In these cases there is no
terview typically taking between 1 and 2 h dicrect blame of the patient and the remark
to carry out. The interview is conducted is consequently not considered critical.
with the patient's closest relative and is au- Remarks which are rated as critical be-
diotaped for later coding. Over the course cause they involve changes in the speed, in-
of the interview, the relative (who is most flection, or pitch of voice of the speaker
frequently a parent or a spouse) is asked cannot be retracted in this way, however.
questions about the emotional climate in While it is not easy to convey the essence of
the home in the 3 months prior to the pa- critical remarks which involve tone change
tient's admission to the hospital. Informa- using printed examples, the following il-
tion is obtained about the events which had lustration, taken from Kuipers (1979), is
taken place during this time and about the helpful.
relative's feelings toward the patient and his The words 'every morning he goes to buy the
or her condition. It is on the basis of the newspaper' have innocuous content but can be
emotions expressed while talking about the said in a variety of ways to give different emo-
patient that ratings of EE in the relative are tional meanings. If they were intended to be criti-
made. cal, this would be conveyed by writing stress
A total of five different ratings are made. marks - 'every morning he goes to buy the news-
paper.'
These include criticism, hostility, emotion-
al overinvolvement, warmth, and positive Emphasis on the first word thus conveys cri-
remarks. While only the first three of these ticism - in this example, criticism of the
have featured prominently in the literature regularity with which the patient goes out to
thus far, brief descriptive details of all five buy the newspaper.
scales will be given below.
Hostility:
Unlike criticism, which, as can be seen from
Criticism: the above illustration is situation specific,
Criticism is the sum total of critical remarks hostility involves a greater generalization of
the relative makes about the patient during negative feeling and usually includes re-
the course of the interview. Remarks are marks critical of the patient himself rather
judged as critical on the basis of (a) their than of his particular actions or behaviors.
content or (b) voice-tone changes. For a re- Examples of hostility include generalized
mark to be coded as critical on grounds of criticism (e.g., "He is stupid. Everything he
content, there has to be clear evidence of does is stupid. ") or of direct rejection ("It's
dislike, disapproval, or resentment on the just unbearable sometimes to be with her").
part of the speaker, e.g., "It's annoying While criticism is measured by simplyrecor-
coming in at night and finding breakfest ding the frequency of critical remarks the
things still on the table." A respondent can relative makes about the patient, hostility is
"opt out" of a remark which is critical only rated using a three-point scale. Although
in content if he or she implies that imper- initially incorporated into early definitions
fections in himlherself are in some way re- of EE (Brown, Birley, and Wing, 1972),
sponsible for the reaction shown, e.g., "It hostility ratings are now no longer used in
really annoys me when she does that but this way - principally because of the strong
Introduction to EE Measurement and Research 27
association between hostility and criticism tionship may be important in helping us un-
and the lack of predictive power of the hos- derstand why some patients do not relapse,
tility ratings when used alone. even when living within high EE families.
Like criticism, warmth is rated by focus-
ing on tonal change in the speaker. In this
Emotional Overinvolvement: case, however, the voice tone has to be
Emotional overinvolvement reflects a dra- clearly positive. Positive remarks, on the
matic or exaggerated emotional response to other hand, are defined primarily by con-
the patient's illness (e.g., "I said what hos- tent and reflect unambiguous praise or ap-
pital? Just imagine how I felt! I thought I'd preciation for some characteristic or behav-
have to go there myself from the shock.") or ior of the patient (e.g., "He's a wonderful
behavior which is excessively overprotec- husband."). Although the rating for posi-
tive ("I quit my job and went into debt so I tive remarks is based on the number of re-
can be home in case he ever needs me."). marks occurring during the interview,
Like hostility, emotional overinvolvement warmth is rated using a five - or six-point
is rated on a point scale, although typically scale.
this involves five or six points rather than Even though the principal component of
three. the EE rating (criticism) is rated primarily
The two final assessments, warmth and by focusing on what can often be quite sub-
positive remarks, have been given relatively tle tone changes in the voice of the relative,
little attention in the EE literature, probab- with adequate training it is possible for
ly in large part because empirically they highly reliable ratings to be made. EE train-
have been found to add little to the predic- ing typically takes about 3 weeks, and be-
tive power of EE ratings made using criti- fore a trainee is permitted to work inde-
cism and overinvolvement. However, they pendently, interrater agreement on criti-
are mentioned here for completeness and cism and emotional overinvolvement must
also because, at some future time, these be at least 0.80 (Pearson product-moment
positive aspects of the patient-relative rela- correlation) .

EE and Schizophrenia: Recent Research


Serveral studies have now provided evi- they show either a change in state (i.e.,
dence that levels of relatives' expressed from non schizophrenic to schizophrenic)
emotion, measured while patients are still during follow-up or exhibit a marked
in the hospital, are reliably associated with exacerbation of symptoms. One important
patients' psychiatric relapse in a 9-month point to note is that since relapse does not
period following discharge (Brown et aI., necessarily involve readmission to a hospi-
1972; Vaughn and Leff, 1976; Vaughn, Sny- tal, relatives' attitudes toward hospitaliza-
der, Freeman, Jones, Fallo, and Liberman, tion or their ability to cope with a pychiatri-
1982). Typically, a cutoff of six or seven cri- cally ill family member without medical as-
tical comments and/or marked evidence of sistance are not factors which can confound
emotional overinvolvement is used to as- the association between relapse and levels
sign relatives to the high or low EE groups. ofEE.
While relapse rates for patients living in Since EE has been demonstrated to be
high EE families are generally around 55%, reliably associated with the risk of relapse in
those for patients who live with low EE re- English schizophrenic samples, it is particu-
latives approximate 15%. larly encouraging to note that the associa-
In all EE research, relapse is determined tion between levels of EE and relapse re-
using the present state examination (PSE) tains its predictive validity cross-culturally.
(Wing, Cooper, and Sartorius, 1974) - a Work recently carried out on an American
semistructured standardized interview population by Vaughn and her associates
widely used for psychiatric assessment. Pa- (see Vaughn et aI., 1982; also Vaughn, Sny-
tients are considered to have relapsed if der, Jones, Freeman, and Falloon, 1984)
28 J. M. Hooley
used a sample of 54 schizophrenics from the research extends, however, it is likely that
Los Angeles area. As with the British sam- some instances of nonreplications will be
ples, family levels of EE were found to be reported in the near future. The findings of
significantly associated with patients' 9- studies reporting a failure to replicate will
month relapse rates, the percentages of re- do much to benefit EE research generally
lapsing patients in the high and low EE since they may provide some insights into
groups being remarkably similar to those the precise mechanism by which EE opera-
previously found for the English samples tes within the relapse process. More de-
(56% vs 17%). scriptive information about the types of pa-
Much work is now being conducted using tients who do or do not respond to high EE
even more diverse cultural groups. As EE influences will be of clear value.

Factors Interacting with EE Levels


At the present time, we know that a sub- Brown's earlier work had suggested
stantial number of patients fail to relapse, (Brown et al., 1962), in cases where schizo-
even when exposed to high EE families. In- phrenic patients spend only limited
creased knowledge about protective factors amounts oftime (less than 35 h/week) with
which attentuate the impact of such rela- high EE relatives, some protection from
tives is of evident benefit for preventive their negative effects seems to be afforted
psychiatry and might, in addition, lead to (see Brown et aI., 1972; Vaughn and Leff,
the development of more sophisticated and 1976).
precisely targeted techniques of interven- Medication also seems to be beneficial
tion. for patients exposed to a high EE relative.
At the present time, there are data to sug- When Vaughn and Leff (1976) analyzed
gest that three factors do interact with rela- data from their own study together with
tives' levels of EE and can serve to modify that collected by Brown et aI. (1972), they
the influence of high EE families. The first found that while 78% of patients living in
of these is the amount of time patient and high EE families and not taking phenothia-
relative spend in face-to-face contact. As zines relapsed during follow-up, only 25%
Total group
Low EE = 71 patients

High EE = 57 patients

LowEE High EE
(13%) (51%)

~
< 35 hrs > 35 hrs

Subgroups
2 3
A 4 5
A 6

not not not


on drugs on drugs on drugs on drugs on drugs on drugs
(12%) (15%) (15%) (42%) (53%) (92%)
Fig. 1. Relapses rates (%) for patients who returned to high and low EE homes at 9-month follow-up
as a function of medication compliance and degree of relative-patient contact. Data combined from
Brown et aI. (1972) and Vaughn and Leff (1976) studies.
Introduction to EE Measurement and Research 29
of patients also living in high EE homes but events. Research published in 1980 by Leff
regularly taking drugs did so. and Vaughn investigated the factors asso-
Moreover, the protective effects of de- ciated with a schizophrenic episode in 37
creased contact time and regular mainte- patients. While episodes of schizophrenia
nance medication appear to be additive. As in patients coming from high EE families
Figure 1 shows, while patients in the high did not seem to be triggered by an excess of
EE group who take drugs regularly and independent life events, such events do
spend less than 35 h1week in direct contact seem to be implicated in the relapses of pa-
with their families have a relapse rate com- tients coming from low EE homes. These
parable to patients from low EE homes data thus suggest that a schizophrenic epi-
(15%), the risk of relapse increases mar- sode can be associated either with contin-
kedly in the absence of these two protective ued exposure to a high EE relative or by an
factors. Thus, the highest rate of relapse elevated number of independent life events
(92%) is found in patients who have a high in the months preceding the onset of the
degree of contact with their high EE fami- episode. Thus, both life events and critical
lies and who in addition are not taking neu- attitudes in relatives seem to constitute un-
roleptic drugs. acceptable forms of stress for such psychia-
The third factor which appears to interact trically vulnerable individuals.
with levels of EE concerns independent life

Psychophysiological Investigations
In an attempt to learn more about how high n = 30), no longer appears to do so. Stur-
EE effects might operate to influence re- geon, Turpin, Kuipers, Berkowitz, and
lapse rates in schizophrenic patients, re- Left's (1984) data now show no differential
search has, in recent years, turned to psy- effect of EE on the decline in electrodermal
chophysiological studies. These typically activity after the relative joins the patient
assess peripheral autonomic responses to and interviewer. Also, in contrast to Tarrier
high and low EE relatives, and recently et al., Sturgeon and his collegues report a
some interesting if conflictual data have mean rate of skin conductance in the high
emerged. EE patient group which is almost double
In a study carried out in 1979 in a group of that found in the low EE patients.
schizophrenic patients in remission, Tarrier, Since Sturgeon was using an acutely ill
Vaughn, Lader, and Leff were able to de- patient group, all of whom had high levels
monstrate that while both high and low EE of face-to-face contact with their relatives,
patient groups showed highly aroused phy- and since all his recordings were made while
siological response patterns during a IS-min the patient was in the hospital rather than at
period spent talking to a psychiatrist, short- home, there are a number of differences
ly after their relatives entered the room, the between the two studies which might ac-
rates of spontaneous fluctuations in skin count for the discrepant results. While it is
conductance in the patients with low EE re- difficult to understand the implications of
latives quickly habituated and approached the studies in the area of psychophysiology
normal levels. Patients with high EE rela- to date (many of the results seem to depend
tives on the other hand showed no such on the physiological index chosen and the
habituation upon entry of the relative. In- method of statistical analysis employed), it
stead, their arousal levels remained high does seem that patients do differ in their
throughout the full 30 min of recording. electrodermal activity according to the EE
While Sturgeon, Kuipers, Berkowitz, Tur- levels of their relatives. Whether these dif-
pin, and Leff (1981) later claimed to have ferences appear after the relative enters the
replicated Tarrier et al.'s earlier finding, a room or whether they are more long-stand-
recently published reanalysis of these initial ing is not yet clear however.
data, together with data subsequently col- Data from Valone, Goldstein, and Nor-
lected on an additional ten patients (total ton (1984) even suggest that mere antic-
30 J. M. Hooley
ipation of an interaction with a high EE rel- more chronic stress associated with high
ative can be arousing. Disturbed adoles- levels of contact with a high EE relative
cents who were waiting to interact with a seeming most crucial. Sturgeon et al. hy-
high EE parent showed higher levels of psy- pothesize that the rise in SCR frequency
chophysiological reactivity than adoles- which takes place in low EE patients during
cents who were anticipating interactions a psychiatric episode is a more transient
with a low EE parents. Moreover, within phenomenon than the rise which occurs in
direct interactions, high EE parents and high EE patients. They suggest this is be-
adolescents become significantly more phy- cause the former have been exposed to
siologically aroused than parents and off- more acute stress prior to the episode while
spring in the low EE group, although prior the latter group have endured life stress
to the interaction no differences in reactivi- which is more chronic. If electrodermal
ty level were evident in the parents. activity is thus in some way associated with
Valone et al.'s data provide good evi- vulnerability to relapse, this slow recovery
dence that encounters with high EE parents rate, argued to be characteristic of patients
are more emotionally arousing than compa- in the high EE group, would render such
rable interactions involving low EE family patients at increased risk of subsequent re-
members. Given this, an hypothesis pro- lapse until remission levels can be estab-
posed by Sturgeon and his co-workers is of lished.
some interest. One explanation these re- While the above is an attractive formula-
searchers offer for their finding that SCR tion and provides an alluring link between
frequencies differ between the high and low several areas of EE research, it must be
EE patient groups concerns a factor which stressed that at the present time the issue of
often precipitates relapse or onset in the the relation between electrodermal activity
two groups. As has been mentioned earlier, and vulnerability to schizophrenia cannot
within the low EE group, a schizophrenic be resolved. Clearly, however, psychophy-
episode is most frequently preceded by the siological studies have a valuable role to
acute stress of an independent life event play in EE research and are likely to pro-
(Leff and Vaughn, 1980). In the high EE vide some important insights into the
patient group, however, life events seem to dynamics of the concept in future years.
play a less important role in relapse, the

Characteristics of mgh and Low EE Relatives


High EE relatives are not easy to spot - at is thus not clearly apparent to an untrained
least by the untrained observer (see Hoo- observer. EE is therefore not measuring
ley, 1984). Despite being able to discrimi- anything obvious to the layman. It is by con-
nate maritally dissatisfied individuals from trast a rather esoteric measure, the subtle
those who reported satisfactory marriages nature of which is reflected in the long train-
by ratings made of couples' videotaped in- ing period necessary to rate reliably.
teractions, ratings of positive and negative Nevertheless, insofar as it is tapping im-
behavior made by an observer blind to the portant aspects of family functioning, EE
EE levels of the individuals concerned did remains a valuable construct. Given this,
not reveal any significant differences across however, the issue of what exactly the
EE groups. High EE spouses were thus not measure is reflecting is central to our under-
rated as any less positive or any more nega- standing of the construct. While the psycho-
tives in their interactions with patients than physiological data described above and the
were low EE relatives, nor were any signifi- behavioral research to be described in
cant differences found in the ratings made Chap. 8 are of evident value in illuminating
by patients interacting with such spouses. the nature of the construct, a content analy-
Whatever it is that high EE relatives are sis of the critical remarks made by relatives
doing that is so potentially detrimental to has also been enlightening (Vaughn, 1977;
patients's progress after hospital discharge Vaughn and Leff, 1981).
Introduction to EE Measurement and Research 31
On the basis of a detailed investigation of She's tending to walk the way she sees all the de-
interview material collected from relatives pressive patients walk here. I think she's very im-
of patients participating in their 1976 study, pressionable.
Vaughn and Leff (1981) identified four re- The final difference between high and low
sponse styles which discriminated high from EE individuals described by Vaughn and
low EE individuals. The first of these con- Leff concerns tolerance. Probably to a large
cerned intrusiveness. While low EE rela- degree due to their conviction that the pa-
tives tend to respect the patient's desire for tient is suffering from a legitimate illness,
social distance, high EE relatives seem to low EE relatives appear much more accept-
find this difficult. They frequently invade ing of the low levels of functioning typically
the patient's privacy and undermine feel- found in schizophrenic patients. High EE
ings of autonomy by making repeated eff- relatives, in contrast, often exert considera-
arts to "get through to" the patient. Often ble pressure on the patient to behave in
this takes the form of unsolicited help or ad- ways they consider more normal.
vice. The example below is typical.
He got up one Sunday morning and he sat in the She wouldn't go out voluntarily. We dragged her
chair and I said, "What's the matter? Don't you out sometimes and it was virtually dragging her
feel well?" "No," he said. So 1 said, "Can 1 get out.
you a drink?" "No." "Well it's not very warm.
Don't you think 1 ought to get something to put With reference to this last point, it is warth
on you?" "No." So I left him. 1went back again to noting that Miklowitz, Goldstein, and Fal-
see that he was alright. He was still in the same
position. This was nearly an hour later. So 1 loon (1983) report that patients with high
thought, it's not very warm, he must be getting EE relatives generally have quite good lev-
cold. So 1went out and got a blanket without ask- els of premorbid adjustment. Conse-
ing him and put it on him. "I don't want it," he quently, it is interesting to speculate wheth-
said. And then 1 did break down because 1 er the contrast between this premorbid lev-
thought well what the devil can 1do for him? And el and the level of functioning exhibited
that's when it upset me - when 1 can't do any- during the illness phase might in some way
thing to help him like that. contribute to the critical responses of the
High EE relatives also tend to respond relatives. The idea that high EE relatives
more dramatically to the patient's illness may in some instances be trying to exert
and lack the more controlled coping style control over the patient's behavior in an ef-
found in low EE individuals. Moreover, fort to restore premorbid levels of function-
they are less likely to believe that the pa- ing is developed further elsewhere (Hoo-
tient is genuinely ill. ley, 1985).

Interventions Involving Relatives


EE researchers have always been fully ical data were collected on 42 schizophre-
aware of the correlational nature of their nics during hospitalization and also 2-4
data and the consequent problems in deter- weeks after discharge. In keeping with pre-
mining the direction of the causal arrow vious findings (Brown et aI., 1972; Vaughn
which arise from this. Both Brown et al. and Leff, 1976), patients living in high EE
(1972) and Vaughn and Leff (1976) used a families did not differ significantly from
variety of statistical techniques to eliminate those living in low EE households with re-
the possibility that mediating factors such as gard to their premorbid adjustment or the
the level of behavioral disturbance mani- symptoms and syndromes they exhibited
fested might both lead to high EE attitudes during hospitalization. Moreover, postdis-
in relatives and also increase relapse risk. charge measures also failed to discriminate
Miklowitz et al. (1983) have also recently between patients with low or high EE rela-
addressed this issue. In a study designed to tives. Thus, the general pattern of results
examine the relation between relatives' EE suggests that patients with high or low EE
and key patient attributes, symptomatolog- families are essentially indistinguishable on
32 J. M. Hooley
measures of the severity of the clinical con- Clearly, ethical considerations render
dition. The available evidence therefore studies designed to increase EE levels total-
points to the fact that high EE may cause re- ly unacceptable. However, one recent inter-
lapse, although the data can hardly be de- vention trial, designed to do exactly the op-
scribed as unequivocal. posite (see Leff, Kuipers, Berkowitz, Eber-
To demonstrate the direction of the caus- lein-Vries, and Sturgeon, 1982), has had an
al arrow convincingly, the hypothesized in- important influence on the directionality
dependent variable (EE) must be external- question. Since this study is described in
ly manipulated, and the consequent effect Chap. 17 of this volume and Sect. B of the
on the dependent variable (patient's re- book deals specifically with family inter-
lapse rates) observed. Only when it can be ventions, little further remains to be said
demonstrated that a modification of EE here. It is evident, however, that social in-
levels leads to a resulting change in relapse terventions of this nature have a very im-
rates can any issues of causality be fully re- portant role to play in relapse prevention
solved. and will continue to form an active area of
EE research in coming years.

EE and Depression
So far in this chapter, only research carried between EE and relapse might not be a phe-
out in schizophrenic patients or individuals nomenon uniquely associated with schizo-
considered to be at risk for schizophrenia phrenic samples.
spectrum disorders has been considered. Since the cutoff of two critical comments
While this is only appropriate, given that utilized by Vaughn and Leff was deter-
schizophrenia has been central to almost all mined post hoc, a replication of the study
the research involving EE, some mention was clearly needed before more generality
should perhaps at this point be given to two for the EE construct could be claimed. The
studies which have examined the relation first full replication and extension of
between EE and relapse rates in depressed Vaughn and Leff's 1976 study has recently
populations. been completed by the author (see Hooley,
Vaughn and Leffs study of 1976 was the Orley, and Teasdale, in press) in a sample of
first to suggest that depressed patients, like 39 patients admitted to psychiatric hospitals
schizophrenics, might be vulnerable to the suffering from an episode of major depres-
influences of high EE relatives. Using a sive disorder. All patients involved in the
group of 30 depressed hospital inpatients, study were married, and consequently all
whose symptom pattern involved no delu- key relatives interviewed were spouses.
sions or hallucinations, Vaughn and Leff While no demographic or illness-related
were able to show that while the thresholds variables, such as number of symptoms,
of six or seven critical remarks which had severity of depression, or duration of the
been so useful in schizophrenic populations key depressive episode, were significantly
did not reveal any significant associations associated with 9-month relapse rates, a
with relapse when used on data from the de- significant relation between spouses' EE
pressed sample, decreasing the cutoff to levels and probability of relapse was evi-
two critical remarks did produce significant dent. Although 59% (14120) of patients liv-
effects. Specifically, when this lowered ing with spouses rated as high EE (two or
threshold was used to assign relatives as more critical comments made during CFI)
high or low EE, 67% (141:21) of patients liv- relapsed during follow-up, none (0/5) of the
ing with high EE relatives relapsed over the patients living with low EE spouses did so.
9-month follow-up period. In contrast, only These results thus provide confirmation of
22 % (2/7) of patients living with low EE re- Vaughn and Leff's original findings and
latives did so. These results were thus inter- suggest that the EE construct not only has
esting since they were the first to suggest predictive validity with respect to schizo-
that the previously well-established relation phrenic patients, but is also a potentially
Introduction to EE Measurement and Research 33
valuable predictor of relapse in depressed depressed patients, this is clearly an impor-
populations. While no intervention studies tant next step.
involving EE have yet been conducted with

Concluding Remarks
Despite the strength of the association be- related issues focus attention quite rightly
tween EE and relapse, we still know rela- on techniques of intervention - techniques
tively little about the mechanism by which to reduce high EE levels - we should also
EE might operate to bring about a return of consider that high EE in relatives may not
symptoms in psychiatric patients. Although invariably be a bad thing. Perhaps, as a con-
we now know more about the correlates of sequence of the attitude they adopt and
high and low expressed emotion attitudes, the behavior they show, high EE relatives
we still need to know much more about how promote higher levels of patient function-
EE can operate to affect patients when they ing than low EE relatives. True, patients
return home. High EE relatives seem in may relapse more often, but they may also
some way to constitute a form of increased achieve higher levels of intermorbid adjust-
social stress for vulnerable individuals. Al- ment which might, in turn, increase their
ternately, low EE relatives can be construc- overall psychosocial stress levels and conse-
ted as individuals capable of lowering stress quently their relapse risk. Thus, while inter-
levels in vulnerable patients. Regardless of vention studies such as that of Leff et al.
which perspective is taken, the psychiatric have demonstrated that high EE relatives
patient is seen as an individual who, for can learn much from exposure to the coping
whatever reason, seems excessively sensi- styles of low EE relatives, some of the po-
tive to the effects of social stress. tentially beneficial aspects of the high EE
While it is important to know what fac- attitude might also be valuably conveyed to
tors contribute to this sensitivity in patients, low EE relatives. Many challenging ave-
it is also important for us to learn more nues of research still await researchers in
about the development of EE in relatives. the field, and may important and fundamen-
What makes a relative high in EE? Is it a tal questions still remain to be answered.
trait? Are certain individuals born high in The next few years will be an important
EE or does it arise as a consequence of ex- time for EE research. Our understanding of
posure to a psychiatrically ill patient? If so, the dynamics of this valuable construct is
what kinds of patients and in response to only just beginning.
what kinds of symptoms? While practically

References
Brown, G. W. (1959). Experiences of discharged ish Journal of Preventative Social Medicine,
chronic schizophrenic mental hospital patients 16,55-68.
in various types of living group. Millbank Me- Brown, G. W., and Rutter, M. L. (1966). The
morial Fund Quarterly, 37, 105-13l. measurement of family activities and relation-
Brown, G. W., Birley, J. L. T., and Wing, J. K. ships. Human Relations, 19,241-263.
(1972). Influence of family life on the course of Hooley, J. M. (1984). Criticism and depression.
schizophrenic disorders: A replication. British Unpublished D. Phil. thesis, University of
Journal of Psychiatry, 121,241-258. Oxford.
Brown, G. W., Carstairs, G. M., and Topping, Hooley, J. M. (1985). Expressed emotion: A
G. C. (1958). The post hospital adjustment of review of the critical literature. Clinical Psy-
chronic mental patients. The Lancet, II, chology Review, 5, 119 - 139.
685-689. Hooley, J. M., Orley, J., and Teasdale, J. D. (in
Brown, G. W., Monck, E. M., Carstairs, G. M., press). Levels of expressed emotion and
and Wing, J. K. (1962). The influence offamily relapse in depressed patients. British Journal of
life on the course of schizophrenic illness. Brit- Psychiatry .
34 J. M. Hooley
Kuipers, L. (1979). Expressed emotion: A J. P. (1979). Bodily reactions to people and
review. British Journal of Social and Clinical events in schizophrenia. Archives of General
Psychology, 18,237-243. Psychiatry, 36, 311-315.
Leff, J., Kuipers, L., Berkowitz, R., Eberlein- Valone, K., Goldstein, M. J., and Norton, J. P.
Vries, R., and Sturgeon, D. (1982). A control- (1984). Parental expressed emotion and psy-
led trial of social intervention in the families of chophysiological reactivity in an adolescent
schizophrenic patients. British Journal of Psy- sample at risk for schizophrenia spectrum dis-
chiatry, 141, 121-134. orders. Journal of Abnormal Psychology, 93,
Leff, J., and Vaughn, C. (1980). The interaction 448-457.
of life events and relatives' expressed emotion Vaughn, C. E. (1977). Patterns of interaction in
in schizophrenia and depressive neurosis. Brit- families of schizophrenics. In H. Katschnig
ish Journal of Psychiatry, 136, 146-153. (Ed.). Schizophrenia: The other side. Vienna:
Miklowitz, D. J., Goldstein, M. J., and Falloon, Urban and Schwarzenberg.
I. R. H. (1983). Premorbid and symptomatic Vaughn, C. E., and Leff, J. P. (1976). The in-
characteristics of schizophrenics from families fluence of family and social factors on the
with high and low levels of expressed emotion. course of psychiatric illness. British Journal of
Journal of Abnormal Psychology, 92 (3), Psychiatry, 129, 125 - 137.
359-367. Vaughn, C. E., andLeff, J. P. (1981). Patterns of
Rutter, M., and Brown, G. W. (1966). The re- emotional response in relatives of schizophre-
liability and validity of measures of family life nic patients. Schizophrenia Bulletin, 7 (1),
and relationships in families containing a psy- 43-44.
chiatric patient. Social Psychiatry, 1,38-53. Vaughn, C. E., Snyder,K., Freeman, W.,Jones,
Sturgeon, D., Kuipers, L., Berkowitz, R., Tur- S., Falloon, I., and Liberman, R. (1982). Fami-
pin, G., and Leff, J. (1981). Psychophysiologi- ly factors in schizophrenic relapse: A replica-
cal responses of schizophrenic patients to high tion. Schizophrenia Bulletin, 8 (2), 425-426.
and low expressed emotion relatives. British Vaughn, C. E., Snyder, K. S., Jones, S., Free-
Journal of Psychiatry, 138,40-45. man, W. B., and Falloon, I. R. H. (1984).
Sturgeon, D., Turpin, G., Kuipers, L., Berko- Family factory in schizophrenic relapse. Archi-
witz, R., and Leff, J. (1984). Psychophysiologi- ves of General Psychiatry, 41,1169-1177.
cal responses of schizophrenic patients to high Wing, J. K., Cooper, J. E., and Sartorius, N.
and low expressed emotion relatives: A follow- (1974). The description of psychiatric symp-
up study. British Journal of Psychiatry, 145, toms: An introduction manual for the PSE and
62-69. catego system. London: Cambridge University
Tarrier, N., Vaughn, c., Lader, M. H., and Leff, Press.
3. Expressed Emotion in Cross-Cultural Context:
Familial Responses to Schizophrenic Illness
Among Mexican Americans*
J. H. Jenkins, M. Karno, A. de la Selva, and F. Santana

Culture and Schizophrenic Outcome


Over the past several decades, a variety of six more industrialized countries of Czecho-
cross-cultural studies have been under- slovakia, Denmark, Taiwan, the United
taken to explore the relationship of culture Kingdom, the United States, and the USSR
to schizophrenia (cf. Draguns, 1980; Ken- (World Health Organization, 1979).
nedy, 1974; Sauna, 1980). Several investi- The systematic methods of data collec-
gators (e.g., Murphy, 1982, p. 78) have con- tion of the IPSS lend a high degree of cred-
cluded that schizophrenia is "widely distrib- ibility to their findings. However, even
uted around the world" and "takes a rather prior to publication of the IPSS outcome
similar form in all the diverse societies in data, there had existed a body of evidence
which it is found." In light of these data, it to suggest that the course of schizophrenia
may have seemed reasonable to assume is, indeed, cross-culturally variable. Several
that schizophrenia is not significantly in- reports of a favorable, nondisabling course
fluenced by sociocultural forces. However, for the disorder have come from various
in the wake of recent findings by the World parts of the non-Western world, including
Health Organization, such an assumption Africa (Jilek and Jilak-Aall, 1970; Kenne-
now appears unfounded. dy, 1974; Lambo, 1955), China (Rin and
There is strong evidence that the out- Lin, 1962), Sri Lanka (Waxler, 1977), and
come of schizophrenia varies across cul- Mauritius (Murphy and Raman, 1971).
tures. Furthermore, this variation does not Review of the IPSS findings concerning
seem to occur without regularity or pattern. differential prognosis led Sartorius, Jablon-
The International Pilot Study of Schizo- sky, and Shapiro (1978) to conclude that
phrenia (IPSS) 2-year follow-up of 1202 pa- social and cultural factors may playa role in
tients in nine countries revealed that pa- schizophrenic outcome. Although the IPSS
tients from the three developing nations of investigators did not collect data specifical-
Nigeria, India, and Colombia had a more ly designed to analyze the sociocultural con-
favorable course than did patients from the text, they nonetheless concluded that the
family may have an important influence on
* The authors wish to acknowledge the research the patient. In particular, they have sug-
projects and sources of funding upon which this gested that "differences in the intensity of
chapter is based: "The Course of Schizophrenia family bonds, in the type of family structure
among Mexican-Americans," Marvin Kamo, ... may make it more or less difficult for a
M.D., Principal Investigator, National Institute schizophrenic patient to return to the com-
of Mental Health, MH-33502 and 39011; "Family munity and remind in remission" (World
Factors," Christine Vaughn, Ph.D., Principal In- Health Organization, 1979, p. 371).
vestigator, recently reported upon by Vaughn Other investigators have made similar in-
et al. (1984); "Developmental Processes in Schi-
zophrenic Disorders," Keith Nuechterlein, terpretations related to benign schizophren-
Ph.D., Principal Investigator, MH-30911. ic outcome that support the need for fami-
Anglo-American data from the two latter pro- ly and community studies. For example,
jects were generously made available to Jenkins Rin and Lin (1962) found that a relative
(1984), for which we are grateful. lack of stigma was attached to mental illness
36 J. H. Jenkins et al.
among a Taiwanese population. The au- and Chapman, 1973; Leff, 1976), the home
thors speculated that the community might environment may prove influential to the
contain therapeutic resources such as "the course of illness. H. B. M. Murphy (1978)
intimate and close emotional ties between has posited that a biologically based infor-
members of a family and also a clan or vil- mation processing deficit in those vulnera-
lage, and the abundance of opportunities ble to schizophrenia may express itself as
for group and community participation in overt illness under conditions of stress
respect to daily life, farming, and festivals" (within or without the family setting),
(Rin and Lin, 1962, p. 145). Similarly, Wax- which overburden the individual's deficient
ler has proposed that the apparently benign information-processing capacity while at
outcome for schizophrenic patients in Sri the same time preventing him or her from
Lanka rested in part on close familial in- escaping the demands of the situation. He
volvement and expectations of responsibili- theorizes that different cultures impose dif-
ty for the afflicted family member. ferent degrees of difficulty on those who are
As Kleinman (1980) has recently pointed vulnerable to schizophrenia by means of
out, the family sector of health care has yet varying combinations of expectations and
to be fully appreciated in the daily manage- supports. Investigation of these sociocultur-
ment of illness episodes worldwide. For al processes has often been discussed gener-
persons suffering from schizophrenia, who ally at a community or societal level of
appear to be particularly sensitive to their analysis, but can be more specifically ad-
immediate social environment (Chapman dressed within family settings.

Family Studies of Expressed Emotion


For well over 2 decades, researchers from from relapse if they regularly took antipsy-
London, England have conducted studies chotic medication or were not in frequent
related to the sensitivity of the schizophren- contact with their high EE relative.
ic individual to the emotional atmosphere Vaughn, Snyder, Jones, Freeman, and Fal-
of the family environment (Brown, Birley, loon (1984) reported remarkably similar
and Wing, 1972; Brown and Rutter, 1966; findings for Anglo-American families living
Vaughn and Leff, 1976a). Their work has in Southern California, although some dif-
centered on the concept of expressed emo- ferences were observed with respect to the
tion (EE). The development of the concept presence of protective factors. In the Unit-
has been reviewed elsewhere (Kuipers, ed Kingdom, the high EE relapse rate was
1979; Leff, 1976; Hooley, this volume). partially mitigated if at least one of two pro-
A study by Vaughn and Leff (1976a) con- tective influences (medication compliance
firmed the earlier findings of Brown, Bir- or reduced contact with a high EE relative)
ley, and Wing (1972) that high EE was the was present. Schizophrenics within the Cali-
single most potent predictor of clinical re- fornia sample were similarly protected only
lapse, although patients who lived with high if both factors were present.
EE relatives were substantially protected

Family Factors and Schizophrenia Among Mexican-Americans


The influence of family factors on schizo- inpatient and outpatient settings (Karno,
phrenia among Mexican-Americans is un- 1966; Karno and Edgerton, 1969; Keefe,
known but the subject of much specula- Padilla, and Carlos, 1978; Lopez, 1981; Sue,
tion. Until recently, Mexican-Americans 1977; Weaver, 1973). Based on similar data
have been significantly underrepresented from the state of Texas and from his obser-
as psychiatric patients in proportion to their vation of Hispanic culture, Jaco (1959) hy-
numbers in the general population through- pothesized that the Mexican-American
out the Southwestern United States in both family provided a closely meshed psycho-
Expressed Emotion in Cross-Cultural Context 37
social support network which tended to ing with the family, whereas English-speak-
protect its members against the develop- ing Mexican-American respondents agreed
ment of psychotic disorders. Madsen's eth- with Anglo-American respondents that re-
nographic studies among Mexican-Ameri- covery would most likely occur by having
can families in the Rio Grande Valley in the afflicted individual removed to an out-
South Texas led him to support Jaco's hypo- side treatment setting (Edgerton and
thesis. As summarized by Madsen, "The Karno, 1971). The Edgerton-Karno
most important role of the individual is his group's findings supported the belief that
familial role and the family is the most val- Spanish-speaking Mexican-American fami-
ued institution in Mexican-American socie- lies would, in general, attempt to cope with
ty. The individual owes his primary loyalties the problem of psychotic illness within the
to the family, which is also the source of solidarity of the family. Beyond the nuclear
most affective relations" (Madsen, 1964, family's felt obligation of support, the ex-
p. 17). tended family may provide additional sup-
Regarding the frequently cited orienta- port for a psychotic family member among
tion of "familism" among Mexican-Ameri- Mexican-American families. Keefe, Padil-
cans, an Hispanic scholar has noted that la, and Carlos report that in Southern Cali-
"For the Chicano, the family is likely to be fornia "Mexican-Americans are much more
the single most important social unit in life. likely than Anglos to have large numbers of
It is usually at the core of his thinking and their relatives living in the community ...
behavior and is the center from which his Anglos are more likely to seek help from
view of the rest of the world extends. Even friends, neighbors, coworkers and groups.
with respect to identification, the Chicano Mexican-American's main resource, on the
self is likely to take second place after the other hand, is their extended kin network.
family" (Murillo, 1976, p. 19). Fabrega ... " (Keefe, Padilla and Carlos, 1978b).
(1969) has commented that "Extended Based on the preceding lines of evidence,
family-of-origin ties, family allegiances and an investigation of EE among Mexican-
closeness to relatives are felt to be sources American families of schizophrenic pa-
of psychological support to the individual tients seemed particularly appropriate. A
and he is expected to value these relations- research project entitled "The Course of
ships. Great respect is shown to older rela- Schizophrenia Among Mexican-Ameri-
tives and separate interests of family mem- cans" (COSAMA) was designed to carry
bers are subordinated fo family considera- out a transcultural extension of the British
tions." findings on EE at a greater "cultural dis-
Doubt concerning the Jaco-Madsen hy- tance" than was afforted by the Anglo-
pothesis of a Mexican-American familial American replication of Vaughn et al.
factor providing protection against the de- (1984). The study was intended to evaluate
velopment of major mental disorders led levels of EE among Mexican-American
Edgerton and Karno (1971) to study percep- families living in Southern California in
tions of and response to mental illness in the which a schizophrenic patient would be re-
East Los Angeles Mexican-American com- turning home after discharge from the hos-
munity. Based on 668 in-home interviews, pital and to determine the influence of EE
they found: (a) that primary language usage on schizophrenic outcome. The study,
differentiated between unacculturated which has completed both a pilot and for-
Mexican-Americans on the one hand and mal data collection phase over the past 4
acculturated (English-speaking) Mexican- years, has gathered materials for 70 patients
Americans on the other, the latter being and their families. A discussion of the de-
very like Anglo-Americans in perceptions sign and methodology of the study, togeth-
of mental illness, and (b) that a provocative er with some results entailing data on the
cultural difference was expressed in re- first 30 patients and 49 key family members,
sponse to a hypothetical case of an acutely form the core ofthis initial report. Data will
schizophrenic young woman. Spanish-spea- also be presented for a matched cohort of 30
king respondents expressed the belief that Anglo-American patients and 47 key rela-
such a person would best recover by remain- tives who have been studied under the aus-
38 J. H. Jenkins et al.
pices of the UCLA-MHCRC. 1 Cross-cul- kins, 1984) and will be referred to here in
tural comparisons of these Mexican-Ameri- abbreviated form for purposes of drawing
can and Anglo-American subsamples have cultural contrasts between these two ethnic
been more fully analyzed elsewhere (Jen- groups.

Methodology
with a history which suggested that the pri-
Patients
mary disorder was affective, organic, or
Patients recruited to the COSAMA project drug- or alcohol-related were excluded
have met the following criteria: from the study, as were those who did not
1. Diagnosed schizophrenic by the Present return to live in the household in which they
State Examination (PSE) and DSM-III were living prior to the index admission. At
criteria the time of the PSE, the Brief Psychiatric
2. Of bilateral Mexican descent Rating Scale (Overall and Gorham, 1962)
3. Between 18 and 50 years of age was also completed. Once the patient had
4. Living with parent, spouse, or other been diagnosed as schizophrenic, home
close relative for at least 1 of the 3 visits were scheduled with the patient's fam-
months prior to hospital admission ily.
The patients were recruited exclusively
from public mental health services in the
Assessment of Relatives
counties of Los Angeles and Ventura. With
the exception of ethnicity, the inclusion cri- Within several days after the patient's ini-
teria employed in the Anglo-American stu- tial diagnosis, adult key relatives - those
dies ofEE were similar to those of the Mexi- with whom the patient had an ongoing rela-
can-American project. tionship within the residential household -
were administered the Camberwell Family
Assessment of Patients Interview (CFI), which has been described
in detail by Vaughn and Leff (1976b).
Screening
The CFI is a partially structured inquiry
All patients were initially interviewed by a into the experience of the patient's illness
fieldworker fluent in Spanish, who estab- and its influence upon the life of the family
lished rapport, determined whether the di- during the 3 months prior to index hospitali-
agnosis was likely to be one of schizophre- zation. The CFI typically yields lenghtly
nia, and established that the patient met all and detailed narrations of family events and
other inclusion criteria, and who then ob- the emotional atmosphere of the house-
tained informed consent. hold. The abbreviated version of the CFI
takes about 1.5- 2 hs to complete and is au-
Diagnosis diotape-recorded for later scoring. In par-
ticular, the interviewer probes for and ob-
All patients were interviewed as soon as serves the expression of emotions and atti-
possible after admission - in accord with tudes expressed by family members toward
their capacity to consent and participate - the patient. The initial CFI interviewers of
by a bilingual clinical psychologist who had the COSAMA project (de la Selva and Jen-
been trained to research reliability in the kins) were trained in a 2-week workshop led
PSE. The ninth edition of the PSE was used by Vaughn and Snyder~ followed by several
in its official IPSS Spanish version. Patients months of training in the rating of Anglo-
1 The UCLA Mental Health Clinical Research
Center for the Study of Schizophrenia, MH- 2In the winter of 1980, Christine Vaughn, Ph.D.,
30911, R. P. Liberman, M.D., Principal Investi- and Karen Snyder, M. A., conducted a training
gator. All three research projects reported upon workshop in the administration of the Camber-
here for the Mexican-American and Anglo-Ame- well Family Interview and ratings of expressed
rican data were supported by the UCLA- emotion at Camarillo State Hospital, Camarillo,
MHCRC. California.
Expressed Emotion in Cross-Cultural Context 39
American and British "master" audiotapes three component ratings of EE, viz., the
of the various CFI scales. Both achieved number of critical comments, hostility, and
high interrater reliability scores with the emotional overinvolvement.
original ratings (above Pearson r of 0.90).
Periodic reliability checks were completed
Additional Procedures
within the project to ensure the ongoing re-
liability of the ratings. While the focus of this report is on data col-
lected within the CFI, data from several ad-
ditional procedures were also employed.
Translation and Development
These materials are important for the inter-
of the Spanish eFI
pretation of EE within the Mexican-Ameri-
Two independent Spanish translations of can family context. They include interview
the CFI were made, one by a professional schedules which inquire into following
native Spanish-speaking translator and lan- areas: social-psychiatric histories of the pa-
guage teacher, the other by de la Selva. The tient; sociodemographic data related to the
two translations were integrated into a composition of the household; social net-
single first draft translation, which was then works of the patient; level of acculturation
back-translated into English by Santana of key relatives and patients; and family
(who was "blind" to the CPI in English). members' ethnopsychiatric understandings
The integrated first translation was re- of the nature of schizophrenia and patterns
viewed line-by-line in comparison with the of coping with the problem. Also, ethno-
back-translation and original English ver- graphic observations of the household,
sion to resolve discrepancies and to produce neighborhood, and community were ob-
a semifinal translation that was utilized in tained.
22 pilot interviews with Spanish-speaking Since the primary goal of the project was
relatives of schizophrenic Mexican-Ameri- to assess the relationship of schizophrenic
cans in Ventura and Los Angeles Counties. outcome to family EE profiles, the clinical
These tape-recorded interview experiences status of the patient was regularly monitor-
were than reviewed to produce a final trans- ed. The follow-up phase of clinical status
lation of the CPI, which was revised and has yet to be completed and therefore will
adapted for local, colloquial Mexican- not be reported upon here. The purpose of
American usage. this initial report is the exploration of the
All CFI interviews were scored for vari- nature and meaning of EE among Mexican-
ous scales described by Vaughn and Leff American families coping with schizophre-
(1976b), but the major focus was on the nic illness.

Sample Characteristics
Selected sociodemographic and clinical scale developed by Cuellar, Harris, and J as-
characteristics of the Mexican-American so (1980), both the key relatives and pa-
patients, along with those of the matched tients tended to be relatively unacculturat-
Anglo-American comparison group, are ed. Most (65%) of the key relatives (often
presented in Table 1. The samples are simi- parents) were predominantly or only Span-
lar in many respects. Nearly all of the fami- ish-speaking, while only 43.4% of patients
lies were of lower socioeconomic status ac- were similarly monolingual. The vast ma-
cording to Hollingshead's (1957) index of jority (90%) of the sample were Catholic.
social position. The mean size of household was signifi-
The majority (79%) of the Mexican- cantly different among the Mexican-Ameri-
American key relatives were first-genera- can families compared to that of the Anglo-
tion Mexicanos, i.e., born in Mexico. A American sample, 6.7 and 3.6 persons, re-
similar percentage (73%) of the Mexican- spectively (P < 0.001). Further, Mexican-
American patients were first-generation American households of the present sam-
immigrants. According to the acculturation ple are characterized by large networks of
40 J. H. Jenkins et al.
Table 1. Selected Sociodemographic and Clinical Features of the Mexican-American (MA) and
Anglo-American (AA) Patient Samplesa

Variable MA AA
n % n %
Patients 30 100.00 30 100.00
Sex
Females 11 36.7 11 36.7
Males 19 63.3 19 63.3
Mean age 27.4 25.2
Marital status
Never married 22 73.3 26 86.7
Married 4 13.3 0 0.0
Separated, divorced, widowed 4 13.3 4 13.3
Length of illness
(mean number years) 5.5 4.3
Number of hospitalizations
(mean) 3.1 3.4
Family type
Parental 22 73.3 28 93.3
Sibling 3 10.0 1 3.3
Marital 3 10.0 0 0.0
Other 2 6.7 1 3.3
Socioeconomic status
(Hollingshead two-factor index)
III 1 3.3 2 6.7
IV 14 46.7 13 43.3
V 15 50.0 15 50.0

a Due to rounding error, percentages do not always equal 100%.


Note. From Schizophrenia and the Family: Expressed Emotion Among Mexican-Americans and
Anglo-Americans by J. Jenkins, 1984, University of California, Los Angeles.

locally residing kin who frequently visit the mic support for the families.
household, providing emotional and econo-

EE in Cross-Cultural Context
The importance of the EE construct has lated to familial response to schizophrenia,
been demonstrated for British and Anglo- factors underlying various patterns of EE
American psychiatric patients and their that are culturally distinctive as well as
families; however, its relevance and mean- more universal in nature need to be identi-
ing in other cultural contexts among non- fied. Discovery of features associated with
English speakers must be established if the EE profiles will contribute to the develop-
EE concept is to gain a wider cross-cultural ment of theoretical models informative of
validity. Variation in levels and types ofEE ways in which sociocultural processes may
needs to be explored. Moreover, since EE serve to influence the course of schizophre-
is an index which taps a host of features re- nic illness.
Expressed Emotion in Cross-Cultural Context 41
Cross-Cultural Variability ofEE
Vaughn et al. (1984) reported a signifi- The percentages of EE presented in
cant difference between the EE profiles of Table 2 reveal that EE was rated highest
British and Anglo-American families of among Anglo-American families and low-
schizophrenic patients. Slightly over one- est among Mexican-Americans. While this
half of the British households were low in may seem suggestive of cultural differences
EE (Brown, Birley, and Wing, 1972; in EE, it is necessary to take into considera-
Vaughn and Leff, 1976a) as against only tion other features that could account for
one-third of Anglo-American families. this variation. One such major concern is
While this report is based on comprehen- that of socioeconomic status. Leff (1977,
sive analyses completed for the first 30 fam- p. 321) has highlighted "the importance of
ilies included in the Mexican-American matching for social class in studies of emo-
study, the EE scores for the entire sample tional expression."
(n = 70) will be briefly presented here. To investigate styles of EE that may be
These data, together with those collected related to features that are cultural in na-
for the British and Anglo-American sam- ture, Jenkins (1984) compared the EE pro-
ples, establish the significant variation in files of lower socioeconomic status families.
patterns of EE across sociocultural settings Thirty Mexican-American and 30 Anglo-
and are presented in Table 2. A household American families (Table 1) living in South-
is defined as being high in EE if one or more ern California were studied. The Mexican-
key relative was rated as high in EE. American families were the first 30 recruit-
The above percentage of high vs low EE ed to the COSAMA project described
were made using the original cutoff points above, and the Anglo-American families
(Six or more criticisms and/or a score of were selected from the project reported on
4-5 on the EO! scale) as designated by the by Vaughn et al. (1984) and an ongoing
British researchers. These have been em- UCLA-MHCRC project.3
ployed here for purposes of cross-cultural The results of overall household EE for
comparison. However, it should be noted these matched subsamples are presented in
that upon completion of data collection for Table 3. A striking difference between
all clinical assessments, a different baseline these two ethnic groups was found: Anglo-
could later prove important for the predic- American schizophrenic patients were con-
tion of schizophrenic relapse among Mexi-
can-American families. 3 See Footnote at bottom of p. 38.

Table 2. EE Profiles of Anglo-American, British, and Mexican-American Households


LowEE HighEE
n % n %
Anglo-American (n = 69)a 23 33.3 46 66.7

British (n = 138)b 72 52.2 66 47.8

Mexican-American (n = 70) 41 58.6 29 41.4

a Note. From "Family Factors in Schizophrenic Relapse: A California Replication of the British Re-
search on Expressed Emotion" by C. E. Vaughn, K. S. Snyder, S. Jones, W. B. Freeman, and I. R.
H. Falloon, 1984, Archives of General Psychiatry, 41, pp. 1169-1177.
b Note. From "Influence of Family Life on the Course of Schizophrenic Disorders: A Replication" by
G. W. Brown, L. T. Birley, andJ. K. Wing, 1972, British Journal of Psychiatry, 121, pp. 241-258 and
Vaughn, C., and Leff, J. (1976). The influence of family and social factors on the course of psychiatric
illness: A comparison of schizophrenic and depressed neurotic patients. British Journal of Psychiatry,
129,125-137.
Overall x 2 = 9.90, d.f 2, P < 0.02; Anglo-American-British, Yates corrected x 2 = 5.84, d.f 1, P <
0.02; Mexican-American-British, Yates correctedx2 = 0.530, NS; Anglo-American-Mexican-Ameri-
can, Yates correctedx2 = 7.92, d.f 1, P < 0.01.
42 J. H. Jenkins et al.
Table 3. Comparison of Overall EE Profiles for Mexican-American and Anglo-American Households
of Lower Socioeconomic Status

Mexican-American Anglo-American
(n = 30) (n = 30)
LowEE 17 56.3 5 16.7
HigbEE 13 43.3 25 83.3

Totals 30 100.0 30 100.0

Note. From "Schizophrenia and the Family: Expressed Emotion Among Mexican-Americans and
Anglo-Americans" by J. Jenkins, 1984, University of California, Los Angeles.

siderably more likely to reside in high EE tionship of key relatives (mother, father,
home environments than were their Mexi- sister, and so forth), type of household (pa-
can-American counterparts. rental, marital, sibling), or variation among
It should be noted that the EE percent- the lower levels of socioeconomic status
ages reported upon here for the lower socio- [Hollingshead (1957) levels IV or V] also
economic status Anglo-American compari- proved unrelated to EE profiles. Rather,
son group are typical for the entire subsam- the highly significant difference is account-
pIe of such cases within the study completed ed for by the ethnic identity of the family
by Vaughn et al. (1984). (Mexican-American or Anglo-American).
Thus, it appears that differences in EE This is compelling evidence for major dif-
profiles are related not only to ethnicity but ferences in cultural styles of emotional re-
also to the socioeconomic status of key rela- sponse to schizophrenic illness within the
tives. The higher percentage ofEE (83.3%) family. We turn now to a discussion of some
found here, compared with that of the en- qualitative aspects of these styles and an ex-
tire Anglo-American sample (67%) of 69 ploration of some of the features that seem
families, is due to the selection of cases of to characterize patterns of EE among Mexi-
lower socioeconomic status. Analysis of can-Americans. Materials analyzed for the
variance and covariance revealed that ob- comparably matched Anglo-American
served differences in the EE profiles were sample will be employed to highlight cultur-
not significantly related to patient charac- al contrasts. In light of the finding that eth-
teristics (sex, age, marital status, edul::a- nicity and social class figure prominently in
tion, employment status, number of hospi- styles of emotional expression, it is evident
talizations, length of illness, socially disrup- that a greater appreciation of sociocultural
tive symptomatology, or level of premorbid factors is needed.
adjustment). Furthermore, the type ofrela-

Sociocultural Nature of EE
A first step toward an understanding of the Every cultural system includes patterned ideas
variation in EE among different ethnic regarding certain interpersonal relationships and
groups is appreciation of the fact that EE is certain affective states, which represent a selec-
inherently sociocultural and qualitative in tion from the entire potential range of interper-
nature. This is not to suggest that EE is not sonal and emotional experiences. The child, gro-
wing up within the culture and gradually inter-
amenable to quantitative analysis, but rat- nalizing these premises, undergoes a process of
her to underscore the point that EE indexes socially guided emotional specialization. He
a wide array of behaviors, emotions, and at- learns, in a sense, a special vocabulary of emo-
titudes which are part of an individual's cul- tion.
tural repertoire, developed through proces-
ses of socialization. As noted by Geertz Explantations of cross-cultural differences
(1959, p. 225): in the expression of emotion must include
Expressed Emotion in Cross-Cultural Context 43
an understanding of the "vocabulary of Anglo-American relatives reported feeling
emotion" characteristically employed by sad (particularly those relatives rated low in
individuals. EE), this did not occur as frequently as
among Mexican-American family mem-
bers. Feelings of sadness (tristeza), sorrow
Low EE Profiles Among
(pena), and pity (ltistima) were commonly
Mexican-Americans
voiced. This was especially true of Mexican-
The majority (69%) of Mexican-American American women. Verbalizations of sad-
key relatives were rated low in EE. This fig- ness were often accompanied by evidence
ure varies remarkably from that for the of warmth and sympathy for the patient and
Anglo-American key relatives of the mat- his or her condition.
ched comparison group, as shown in Such expressions of sadness or sorrow
Table 4. over the illness of a close family member
These percentages provide a more indi- may reflect genuine feelings on the part of
vidualized view of EE than does the overall the relative. On the other hand, they should
household index used for predicting re- also be regarded as culturally appropriate
lapse. Clearly, most of the Mexican-Ameri- responses to schizophrenic illness within
can family members tended not to be highly the family. As Nichter (1981) has recently
critical, overinvolved, or hostile toward pointed out, every culture provides its
their ill relatives. While this may indicate members with a variety of ways to express
the absence of certain kinds of verbally ex- emotions, including distress. Faced with
pressed emotions or communications with- what they may view as a serious illness or
in the family, it tells us relatively little about condition - whether temporary or long-
what other sorts of patterns might be ac- term - Mexican-American relatives ex-
tively shaping the household environment. press feelings that acknowledge an inher-
Moreover, the EE percentages do not say ently distressing situation, and the Spanish
anything about whether low EE among language provides a rich lexicon of emotion-
Mexican-Americans is similar in kind to low al terms to express feelings of unhappiness
EE profiles among other cultural groups. or distress. While some low EE relatives ex-
We will now turn our attention to a discus- pressed emotions related to their ill relative
sion of some of the contours and major that included anger or resentment, expres-
components of these low EE Mexican- sions of sadness clearly predominated over
American relatives. those of indignation or antipathy. How-
One of the most striking findings was that ever, several relatives reported that they at-
feelings of sadness as conveyed through the tempted to keep their feelings of sadness to
content and tone of the relatives' verbal be- themselves, fearing that the patient might
havior would often pervade the interviews. be adversely affected by their feelings of
This contrasted sharply with emotional re- being distraught.
sponses characterized by anger, indigna- Low EE profiles of Mexican-Americans
tion, and frustration that were frequently are also linked to ethnopsychiatric views of
displayed by high EE relatives. While the the nature of the problem that has beset

Table 4. Comparison of EE Profiles for Mexican-American and Anglo-American Key Relatives

Mexican-American Anglo-American
(n = 49) (n=47)
LowEE 34 69.4 18 38.3
HighEE 15 30.6 29 61.7

Totals 49 100.0 47 100.0

Note. From "Schizophrenia and the Family: Expressed Emotion Among Mexican-Americans and
Anglo-Americans" by J. Jenkins, 1984, University of California, Los Angeles.
44 J. H. Jenkins et al.
their ill relative. These ethnopsychiatric or sponses to symptom behaviors. A content
"folk" models for interpreting schizophren- analysis of critical comments by Jenkins
ic behavior are complex and merit in- (1984) revealed that Mexican-American
depth treatment that would be beyond the key relatives were far less likely to criticize
scope of this chapter. However, we will at- symptom behaviors than were their Anglo-
tempt to briefly summarize some of the American counterparts. These data provide
more salient aspects of these models and support for the proposition current in the
their relationship to low EE. Of principal literature that Hispanics tend to be relative-
significance is that Mexican-Americans do ly tolerant of psychotic symptomatology
tend to view the problem as one of illness; it (Fabrega, Swartz, and Wallace, 1968; Rog-
would appear that psychosis is commonly Ier and Hollingshead, 1965; World Health
considered to be an illness-related problem Organization, 1979). The Mexican-Ameri-
cross-culturally (Murphy, 1982). Among can relatives demonstrated a great deal of
Mexican-Americans, the problem is often tolerance, patience, and respect toward the
considered to be associated with one's "ner- schizophrenic family member and would
ves" or mental condition. In whatever man- seldom challenge or take exception to psy-
ner the illness may be conceptualized, it is chotic behaviors. Many relatives reported
typically believed to be legitimate. Fre- that confrontations with a sick family mem-
quently, the relatives would refer to the "ill- ber were unwise and did little to change
ness" independent of any prompting from matters.
the interviewer and in advance of any que- Low EE Mexican-American families
ries by the interviewer into the relative's would sometimes interpret symptom behav-
view of the nature of the problem. Most in- iors in a sympathetic or favorable light. For
formants were firm in their conviction that example, one young woman spent a great
the patient suffered from an illness prior to deal of time sitting alone and laughing to
the time that he or she was first hospitalized herself for no apparent reason. Her moth-
for the present troubles. er's view of this behavior was not a critical
Belief in the legitimacy of schizophrenia one; rather, she reported feeling glad that
as an illness is also linked to views that sym- her daughter was able to find some momen-
ptom-related behaviors generally lie out- tary relief from the very difficult circum-
side the patient's control. Some of the fol- stances of her life by simply being able to
lowing comments4 made during the course laugh at her troubles. In another instance, a
of the interviews illustrate this point: mother viewed her son's habit of sleeping
If he doesn't want to do anything it's because he's until early afternoon as potentially benefi-
sick; he always worked hard in school and jobs cial and clearly understandable, given that
before. He must be sick. he was typically up quite late into the night,
I knew right away that this wasn't Luis. I know unable to sleep because he was continually
what he was doing wasn't his fault. bothered by voices. She believed that sleep
She would like to get well ... if she could. was crucial to his recovery and that he
These comments are similar to those made should sleep whenever he was so inclined or
by low EE Anglo-American relatives: able. With respect to this same behavior -
If he could really control himself, I think that he sleeping late - another key relative's re-
would. sponse to his wife's routine of sleeping until
She's always looking for help. She tries the best to noon every day was to say, "Let her sleep as
help herself to get healthy. She tries her best- late as she likes! She is my queen!" These
looking for doctors to help her ... I don't think examples should not be taken as evidence
she could do any more. She's a fighter. She wants that Mexican-Americans do not recognize
to be well. these sorts of behavior as indicative of men-
Ethnopsychiatric views of the nature of the tal illness, for as discussed above, they do.
problem also influenced the relatives' re- Rather, these vignettes should be viewed as
exemplary of relatives' efforts to interpret
4 The qualitative materials reproduced here are such behaviors in a noncritical manner.
verbatim quotations from CFI materials and orig- Finally, low EE profiles among Mexican-
inally appeared in Jenkins (1984). Americans are linked to strong notions of
Expressed Emotion in Cross-Cultural Context 45
the importance of family bonds, which are ments or confrontations, and (4) large kin-
enduring and unchanging. The strength of based households and networks in which a
family ties demonstrated in the face of long- sense of the importance of family bonds
term schizophrenic illness is often remarka- induces relatives to assume responsibility
ble, although the type of relationship (par- for the patient's care and recovery.
ent, spouse, and so on) is often influential.
Mothers tend to be the most devoted, fol-
lowed by fathers, sisters and brothers, and High EE ProfIles Among
spouses. This may be common across a vari- Mexican-Americans
ety of cultural contexts. Much of the Mexi-
can-American relatives' compassion stem- The above positive features of low EE
med from a deeply felt commitment to a households are not universally found
family member, particularly one who is seri- among Mexican-American families. In con-
ously ill. Many relatives reported that they trast to the low EE Mexican-American rela-
felt a great deal more affection for the pa- tives for whom sadness seemed to represent
tient as a result of the illness. Several made a major emotional orientation toward the
passionate statements about how they illness, high EE respondents were likely to
would never, indeed could never, leave express feelings of anger and indignation.
their ill relatives to fend for themselves "in In fact, one of the most common ways a
the streets." high EE Mexican-American relative would
Another feature that we believe is related express criticism would be to comment on a
to the predominance of low EE profiles behavior by saying mi di6 mucho coraje (it
among Mexican-Americans is the size and made me very angry). These relatives were
structure of the families. As was discussed often distressed over behaviors they viewed
earlier in connection with the sample charac- as unacceptable. For example, the father of
teristics, Mexican-American nuclear house- one female patient made seven critical com-
holds tended to be larger than those of the ments during the course of the interview,
Anglo-Americans. In nearly all ofthe Mexi- and within four of these criticisms he made
can-American households, locally residing reference to the anger that certain behav-
kin visit the home frequently, providing iors would provoke in him. These criticisms
emotional and instrumental support and as- centered on the patient's tendency to argue,
sistance. This includes help in alleviating insult and swear at family members, and
the stress generated by living with schizo- throw objects about the house.
phrenic illness. In some families, caretaking Moreover, some high EE relatives, un-
of the ill relative was shared among various like those in low EE families, more often
relatives, thereby allocating the burden of doubted whether their family member was
responsibility among several individuals. truly ill. These relatives would point out
Large family size may also inhibit the devel- that the patient's symptoms would some-
opment of patterns of overinvolvement or times wax and wane. More frequent, how-
critical attitudes and behaviors. For exam- ever, were doubts that their relative could
ple, occasionally, key relatives would ex- possibly be mentally ill. This may indicate
press regret over not having more time to that high EE relatives had a greater tend-
devote to their ill relative, since responsibili- ency to deny the problem of mental illness
ties to other family members tended to de- in their family or to experience greater feel-
tract from their efforts in this regard. ings of shame and stigma associated with it.
To summarize, low EE among Mexican- Thus, one Mexican-American father be-
Americans is patterned along four dimen- lieved that his son might not be truly ill since
sions: (1) sadness as a predominant emo- he sometimes seemed ill and other times
tional response to the problem, (2) ethno- not; in any case, he claimed that it had gone
psychiatric models of schizophrenia that on long enough.
view the problem as a serious, legitimate ill- Among the high EE Anglo-American
ness outside of the patient's locus of con- relatives, often there was doubt or disbelief
trol, (3) styles of coping with troublesome in the legitimacy of the illness. These rela-
behaviors in a manner which avoids argu- tives would express the view that even if
46 J. H. Jenkins et al.
their relative was in fact ill, he or she could ly expressed. For example, Mexican-Amer-
surely exercise powers of personal initiative icans stated flatly that it was important that
and control in determining the course of the their relatives work or be active for their
illness, should they be so inclined. own sakes or in order that they be able to
A lot oftimes it wouldn't have happened if she ... take care of some of their own personal
saw it coming ... to me I think she could have needs.
done something about it and you know with me I He has to dress, to have money, work, so he can
can talk with someone and try to help them, but go out, have a girlfriend, because we can't give it
if they don't help themselves and don't give a all to him.
damn ... that's where it bugs me ... She wouldn't Look, my son, it's not good for someone to sleep
do anything - like she wanted to feel sorry for till 2:00 in the afternoon! We have to go to work,
herself ... She was just giving up ... I don't like to do something! (see Footnote 4).
see that. I don't like to see someone give up when
there's still something to fight for ... I say, "Why Anglo-American relatives, on the other
aren't you trying, don't give up," because to me hand, displayed critical attitudes toward in-
people who do that I can't get along with ... I activity or unemployment, frequently in-
can't get along with someone who sees the prob- ferring negative assessments of their rela-
lem and does nothing, just lets it happen ... and tive's character or personality:
I start to get a dislike.
I don't know if she has a button she can push or . .. he just didn't have no ambition to do anything
what ... that girl can fool you and fool anybody ... 20 years old, right in his prime ... but now he
... She can go like that and be as normal as you or should be involved but he's not. He would just sit
there in the chair and watch TV all the time.
I (see Footnote 4).
No ambition - doesn't care for nothing ... I
There were few differences between high should say doesn't care for anything, class up my
and low EE Mexican-American relatives English. The way I said it was to emphasize that
with respect to criticism of symptom behav- worthlessness of his. Useless.
She's too darn lazy. That's her trouble.
iors. Although generally speaking, high EE Do this today and you want to do this tomorrow,
relatives were more likely to be critical of or you never will make it. You've gotta make up
the patient, there was not a disproportion- your mind and go after it (see Footnote 4).
ate amount of attention focused on symp-
tom behaviors per se. This differed greatly Styles of coping and adaptation to schizo-
from comments made by high EE Anglo- phrenic illness among high EE Mexican-
Americans. They expressed discomfort Americans were typically different from the
concerning psychotic behaviors, as the fol- strategies employed by low EE relatives.
lowing remarks about conversation illus- High EE relatives would attempt to change
trate: undesirable behaviors through scolding,
... bugged the hell out of me, the thing that really admonitions, explanations, and avoidance.
drove me up a wall was her starting a conversa- In contrast to low EE coping styles, these
tion and not finishing it. I mean it really bugged responses were reactive and combative.
me.
She'd talk, talk, talk, talk, talk, about God or
Furthermore, some relatives tended to be
whatever - religion - you can't correct her and intrusive in ways that were uncharacteristic
I would not correct her ... but that constant of low EE relatives. For example, some rel-
drone is enough to drive me up a wall. atives would search through the patient's
I can't even remember some of the horrible personal things or listen in on telephone
things he'd come out and talk about ... and actu- conversations to gamer information con-
ally he was making me nervous. The things that cerning their activities.
he'd talk about (see Footnote 4). These kinds of responses were common
Cultural· differences between Mexican- to high EE Anglo-Americans relatives, as
Americans and Anglo-Americans were also well. These high EE relatives, however,
apparent in criticisms directed toward in- were more likely to report frequent "nagg-
activity or unemployment on the part of ing" of the patient, as the following exam-
schizophrenic relatives. While critical rela- ples demonstrate:
tives of both ethnic groups were likely to I am a nagger, well, normally [about] him doing
complain about these behaviors, they dif- things wrong. I am a nagger. I've tried to break
fered in the nature of criticisms they typical- myself of it, but I do nag him.
Expressed Emotion in Cross-Cultural Context 47
Sometimes I nag. I'm so exasperated ... mostly band since divorce was not possible within
about money [she throws away] and the fact that the Catholic church. This she accepted, al-
she always sits around ... (see Footnote 4). though in one instance she reported that her
Despite the critical attitude displayed by husband's incessant complaints concerning
high EE relatives, this did not alter their the living conditions of the household drove
sense of familial commitment toward their her to exclaim, "Look, if you're not happy
ill relative. In this regard, they did not here, there is the door! I've had it! I'm 'up
markedly differ from low EE relatives. to here!" The fact that only one such in-
There was only one instance in which a key stance occurred lends strong support to the
relative demonstrated a rejecting attitude. prevailing views concerning Mexican-Ame-
This case was a martial household in which rican familism and to the view that Mexi-
the wife, very weary of her husband's con- can-American relatives display high levels
tinuously psychotic condition throughout of acceptance toward schizophrenic rela-
their 9 years of marriage, sought a divorce. tives in the home, even when high EE char-
Her priest, however, counseled against such acterizes the mode of response toward
a move and told her to remain with her hus- them.

Conclusion
Both quantitative and qualitative analyses by schizophrenic illness.
of EE among Mexican-American families Comparative data from a matched sam-
revealed a predominance of low EE styles ple of Anglo-American families demon-
of response to a schizophrenic family mem- strated significant variations in EE across
ber. These low EE profiles were found to be cultures. While Mexican-Americans tended
patterned along several dimensions, many to be typically low in EE, the converse was
of which were notably different from those true of Anglo-Americans, for whom high
characteristically employed by high EE rela- EE profiles dominated. Although some
tives. In general, low EE family members similarities across high and low EE styles for
provided their schizophrenic relatives with these two ethnic groups were noted, there
a great deal of tolerance, sympathy, and were several aspects of EE styles (both high
support. However, not all Mexican-Ameri- and low) that were culturally distinctive to
can individuals responded in this fashion. Mexican-Americans. While these patterns
High EE relatives displayed anger, impa- of response may not be unique to Mexican-
tience, and frustration related to the pa- Americans when viewed in broader cross-
tient's troublesome behaviors. The strength cultural perspective, they do suggest that
of family bonds and affection was typically the sociocultural context may be influential
in evidence for both high and low EE rela- in shaping an individual's response to a schi-
tives alike, despite the difficulties generated zophrenic family member.

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4. Do Relatives Express Expressed Emotion?*
A. M. Strachan, M. J. Goldstein, and D. J. Miklowitz

Introduction
Recent research has shown that family in- 15), the way in which emotional attitudes
tervention programs, in combination with are communicated and problems are solved
neuroleptic medication, can have dramat- may be crucial factors, with expressed emo-
ic effects on the course of schizophrenia in tion (EE) as a key index of such processes.
terms of both psychiatric and social func- This chapter focuses on the interactional
tioning (Goldstein, Rodnick, Evans, May, correlates of EE, a measure based on rat-
and Steinberg, 1978; this volume, Chaps. ings of an interview with a relative. Such
12-14). All these programs have focused ratings have been correlated in a number of
on treating and supporting the family as a studies with direct behavior between the
unit, although it has not always been clear patient and a relative, providing measures
what important aspects of family function- of the congruence and incongruence be-
ing these programs affect. However, as sug- tween behavior in these two situations.
gested by Goldstein and Strachan (Chap.

Early Research on EE and Interaction


Two early papers describe the development spouse in the individual interviews and be-
of a method for assessing the expression of havior toward the spouse in the joint inter-
emotion (Rutter and Brown, 1966; Brown views.
and Rutter, 1966), which was later to be- Results for these 18 wives and 18 hus-
come the Camberwell Family Interview. bands showed that criticisms of their spous-
The original study was of 30 families con- es were much less likely to be expressed in
taining at least one child in which one of the the joint than in the individual interview.
parents had been admitted either to an out- Only 13 people of 36 made one or more criti-
patient psychiatric clinic or to the hospital. cism during the whole hour. This was proba-
For each family, there was 2- to 3-h inter- bly because of the presence of their spouse
view with the patient, a 3- to 4-h interview and because the topic of conversation was a
with the spouse, and (for 18 families only) a
joint interview with the husband and wife • The UCLA research studies were supported by
together, which lasted about an hour. The grants MH08744, MH30911, and MH14584 from
individual interviews focused on the impact the US National Institute of Mental Health and
of the psychiatric problems and on family by a grant from the MacArthur Foundation
relationships. The joint interviews focused (K830902) to support a Network on Risk and
on the family's utilization of medical and Protective Factors in the Major Mental Dis-
orders. The authors are deeply indebted to Ian
social services. At each interview, two Falloon and Julian Leff for their warm spirit of
people made independent ratings of a num- collaboration and to Jeri Doane, Jeanette Nor-
ber of dimensions of emotional expression, ton, Karen Snyder, Keith Valone, and Sibyl
including warmth and critical remarks. Rat- Zaden for their important contributions to vari-
ings were made of attitudes toward the ous phases of this research.
52 A. M. Strachan et al.
relatively neutral one which would tend to sible that attitudes elicited on the CFI are
pull for criticism of external agencies rather imperfectly correlated with interactional
than of each other. behavior and that the predictive validity of
However, it was found that when there the Camberwell-derived EE attitudes in
were any criticisms in the joint interview, anyone study depends upon the degree of
there were nearly always (11 of 13 cases) 10 attitude-behavior correlation observed in
or more criticisms in the individual inter- that particular sample. Surprisingly, despite
view. Conversely, if there was a complete the obvious nature of this issue, it has rarely
absence of criticisms in the joint interview, been addressed in the accumulating litera-
there were usually (21 of 23 cases) fewer ture on EE. A correspondence between
than 10 criticisms in the individual inter- EE-type behaviors in direct family interac-
view. This was a highly significant differ- tion and subsequent clinical outcome would
ence (P < 0.(01). Thus, although the base- provide further support for the hypothesis
rate of critical remarks in the two situation that the affective climate of the family is rel-
was very different, the correspondence be- evant to the course of schizophrenia.
tween the two measures suggested some In our research program, we decided that
cross-situational validity to the rating of at- it was necessary to demonstrate that affec-
titude. The Pearson correlation between tive attitudes expressed by a relative in an
the two measures of criticism was 0.51. For interview corresponded with the manner in
warmth, the correlation was even higher, which that relative spoke when face-to-face
0.68. with the patient. To do this, two things were
The exciting and provocative findings of needed: a standardized situation to evalu-
Brown, Birley, and Wing (1972) and ate interactional behavior and a coding sys-
Vaughn and Leff (1976) stimulated a spate tem that reflected the behavior analogues
of replication studies designed to evaluate of EE attitudes. For the standardized situa-
whether the predicitve validity of the EE tion, we used the direct interaction task
measure holds up cross-nationally and used previously in our prospective longitudi-
cross-culturally (e.g., Chaps. 5, 7, this vol- nal study (Goldstein, Judd, Rodnick, Al-
ume; Vaughn, Snyder, Jones, Freeman, kire, and Gould, 1968) to assess family in-
and Falloon, 1984). While these efforts are teraction in a laboratory setting. In this
very understandable, they have focused modified version, family members were
upon a particular methodology for assess- asked to discuss two emotionally loaded
ing EE, the CFI, and lost sight of the origi- family problems derived from a prior inter-
nal model underlying this research. The ori- view. One problem was initiated by the pa-
ginal hypothesis of the Brown et al. studies tient and the other by a relative. These dis-
was that certain behavior expressed by rela- cussions were recorded in the absence of an
tives toward a recently released schizophre- experimenter.
nic patient increases the stress level within This procedure differs substantially from
the home and lowers the patient's threshold that used by Rutter and Brown (1966).
for relapse. The interactional behaviors First, the interactions are much shorter,
which were identified as important were being closer to 10 min than 1 h. Secondly,
rather specific styles of negative affective no raters are present: family members are
communication within the family. left alone to discuss the topic. Thirdly, the
However, the CFI is not a measure of in- topic is chosen to be one of immediate per-
trafamilial affective communication; in- sonal relevance to the participants. Where-
stead, it measures attitudes toward a patient as Rutter and Brown had couples discuss
expressed within the context of an interview the relatively neutral topic of their use of
with a mental health professional. These at- medical and social services, we had relatives
titudes mayor may not be expressed in face- discuss a much more emotionally charged
to-face interaction with the patient. We issue.
know, from years of research in social psy- For a coding scheme, we used the affec-
chology, that there is rarely isomorphism tive style (AS) coding system developed by
between verbally expressed attitudes and Doane (Doane, West, Goldstein, Rodnick,
overt interactional behavior. Thus, it is pos- and Jones, 1981) which was designed to
Do Relatives Express Expressed Emotion? 53
measure affective attitudes expressed to- Adolescents" by J. A. Doane, K. L. West, M. J.
ward a relative during a direct interaction Goldstein, E. H. Rodnick, andJ. E. Jones, 1981,
task. Some of the codes in this system over- Archives of General Psychiatry, 38, pp. 679 - 685.
lap with the EE dimensions of criticism and Although this scheme was originally de-
emotional overinvolvement. This system veloped to capture aspects of family process
was used to code the interactional data in which the research literature suggested had
our sample of schizophrenic patients and a negative impact, it can be seen that some
their parents. The codes in the AS system of these codes are analogous to the EE mea-
are presented in Table 1. sures. Thus, benign and personal criticisms
are analogous to critical comments. The in-
terpersonal analogue of overinvolvement is
Table 1. Negative Affective Style Codes
reflected in the intrusion code in which one
Criticism person speaks as though they were the ex-
1. Personal criticism pert on the patient's thoughts, inner states,
Unnecessary or overly harsh modifiers and/or and motives. The guilt induction and critical
negative reference to broad classes of behav- intrusiveness codes have elements of both
ior and/or negative evaluation of the child's criticism and emotional overinvolvement.
character or nature A series of three studies has examined
2. Benign criticism the relationship between EE and direct in-
Mild, circumscribed, matter-of-fact, directed teraction. The first study (Valone, Norton,
toward specific incidents or sets of behaviors
Goldstein, and Doane, 1983) examined 52
Guilt induction families in the UCLA Family Project, a lon-
Conveys child is to blame or at fault for some gitudinal prospective study. These families
negative event and parent has been distressed had all come to an outpatient clinic for
or upset by the event
problems with an adolescent offspring.
Intrusiveness Families were selected in which both natur-
Parent implies knowledge of child's thoughts, al parents were living with the adolescent
feelings, or motives without basis for such and in which the offspring was disturbed but
knowledge nonpsychotic. Both dyadic and triadic data
1. Critical intrusiveness
Contains a harsh, critical attribution of intent were available. In all, 28 mothers and 34
2. Neutral intrusiveness fathers were classified as low EE, whereas
Neutral quality; refers to child's emotional 24 mothers and 18 fathers were placed in
states, ideas, preferences, etc. the high EE category, mostly on the basis of
a highly critical attitude. It was found that
Note. From "Parental Communication Deviance high EE parents expressed more benign cri-
and Affective Style: Predictors of Subsequent ticisms and more harsh criticisms toward
Schizophrenia Spectrum Disorders in Vulnerable their offspring than low EE parents when

Table 2. Benign and Harsh Criticisms Expressed to Patients by Dual High, Mixed, and Dual Low EE
Parental Pairs

Benign Criticism Harsh Criticism


Group n Mean (SD) Mean (SD)
a. Dual high EE 11 12.36 (7.55) 7.45 (7.01)

b.MixedEE 20 8.05 (5.32) 2.20 (2.98)

c.DuallowEE 21 4.95 (5.95) 1.43 (1.78)

Significant differences (P < 0.05): benign criticism, c < b, c < a; harsh criticism, a> b, a > c

Note: From "Parental Expressed Emotion and Affective Style in an Adolescent Sample at Risk for
Schizophrenia Spectrum Disorders" by K. Valone, J. P. Norton, M. J. Goldstein, and J. A. Doane,
1983, Journal of Abnormal Psychology, 92, pp. 399-407.
54 A. M. Strachan et a1.
data from both dyads and triads were sum- show that the sharpest predictor of critical
med. When dyadic and triadic data were behaviors from EE attitudes occurred when
examined separately, it was found that high the EE profile of the parental pair was
EE mothers made more benign criticisms examined together, as would be predicted
than low EE mothers in the dyads, whereas by family-systems theorists.
there was no difference for fathers. There Unfortunately, in this study there was an
were trends for both mothers and fathers to almost complete absence of emotionally
use more benign criticisms in the triad. overinvolved parents so that it was not pos-
Next, the authors examined the synergist- sible to study the behavioral correlates of
ic influence of parents on each other's ex- such an attitude. This may have been be-
pression of criticism. They divided the fami- cause the sample was not one of schizophre-
lies into dual low EE (both parents low EE), nics but of problem adolescents who may
mixed EE (one parent high, the other low), elicit critical responses from parents but
and dual high EE (both high EE). They whose protective responses are in the nor-
found that the three parental EE profile mal range. The next two studies to be de-
groups differed significantly in the expres- scribed overcame these drawbacks by study-
sion of both benign and harsh criticism (see ing relatives of schizophrenics, some of
Table 2). More specifically, data analyses whom had emotionally overinvolved atti-
suggested that the high EE parent in mixed tudes.
EE parental pairs is especially prone to ex- Miklowitz, Goldstein, Falloon, and Doa-
press benign criticisms toward the adoles- ne (1984) assessed the relationship between
cent. However, the presence of the low EE EE attitudes and direct interactional be-
spouse in the mixed EE families appears to havior with a sample of schizophrenic pa-
inhibit the frequent expression of harsh criti- tients and their parents from 42 families. A
cism by the high EE parent. These data count was made of the total number of nega-

10

c-
en
Q)
E
8
Critical statements Intrusive statements

--
Q)
til 6
en
0
....
Q)
..c 4
E
:::J
C
c 2
co
Q)
~

0
LowEE High EE- High EE- High EE- Low EE High EE- High EE- High EE-
Critical Overinvolved Critical and Critical Overinvolved Critical and
EOI EOI
(n = 7) (n = 14) (n = 5) (n = 4) (n = 7) (n = 14) (n = 5) (n = 4)

Expressed emotion subgroup


Fig. 1. Mean number of critical and intrusive statements in direct interaction among high and low EE
parental subgroups
Note. From "Interactional Correlates of Expressed Emotion in the Families of Schizophrenics" by
D. J. Miklowitz, M. J. Goldstein, I. R. H. Falloon, and J. A. Doane, 1984, British Journal of Psychia-
try, 144, pp. 482-487.
Do Relatives Express Expressed Emotion? 55
tive AS statements (sum of criticisms and (criticism with critical EE attitudes and in-
intrusive statements) expressed by the par- trusiveness with emotional overinvolve-
ents in triadic discussion between the pa- ment). These data are also significant
tient and his or her parents. The high EE (P < 0.05).
relatives expressed a significantly greater The third study in this series (Strachan,
number of negative AS statements than low Leff, Goldstein, Doane, and Burtt, 1985)
EE parents with means of 9.6 and 5.4, re- differed in three ways from the Miklowitz
spectively (P < 0.002). et al. (1984) study. First, the study was
However, since high EE relatives attain done in Britain, so that a cross-national re-
this status by way of diverse attitudinal pat- plication could be performed. Secondly,
terns (high on criticism, high on criticism the sample of schizophrenics was mostly of
and emotional overinvolvement, and high recent onset. Thirdly, interactional behav-
on emotional overinvolvement only), we ior was assessed from dyadic interactions
investigated whether these subtypes, with between patient and each relative separat-
the high EE group, expressed different styl- ely. Thus, a direct comparison of EE atti-
es of AS as well. Figure 1 presents the fre- tudes with AS behaviors could be conduct-
quency of criticism and intrusive statements ed without the possibly confounding pres-
with the low EE and the different subtypes ence of another relative.
of high EE. We can see that there is notable As in the Miklowitz study, it was found
group differentiation such that the subtypes that high EE relatives expressed a signifi-
of high EE attitudes correspond with dif- cantly greater number of negative AS state-
ferent patterns of interactional behavior ments than low EE relatives, with means of

10

Critical statements Intrusive statements

-
en
c
(1)
8

--
E
(1)
6

-
co
en
0
....
(1)
4
.0
E
::l
C
2
c
co
(1)
~
0
Low EE High EE- High EE- High EE- Low EE High EE- High EE- High EE-
Critical Overinvolved Critical and Critical Overinvolved Critical and
EOI EOI
(n = 28) (n = 11) (n = 16) (n = 7) (n = 28) (n = 11) (n = 16) (n = 7)

Expressed emotion subgroup

Fig. 2. Mean number of critical and intrusive statements in direct interaction among high and low EE
parental subgroups
Note. From "Emotional Attitudes and Direct Communication in the Families of Schizophrenics: A
Cross-National Replication" by A. M. Strachan, J. P. Leff, M. J. Goldstein, J. A. Doane, and
C. Burtt, 1985, manuscript submitted for publication.
56 A. M. Strachan et al.
11.6 and 4.7, respectively (P < 0.02). Fur- cussions around more neutral issues may
thermore, when the high EE relatives were elicit greater differences between relatives
subdivided into those who were critical, in their rate of use of supporting statements.
those who were emotionally overinvolved This thesis is supported by data from Green-
(EOI), and those who were both critical wald, Kornblith, and Hopkins (1980). They
and EOI, a similar pattern to the Miklowitz applied the marital interaction coding sys-
data was obtained (see Figure 2). However, tem to samples of interaction between schi-
it was found in this sample that a critical at- zophrenic patients and their relatives. The
titude was associated with both criticisms discussion topics were more neutral than in
and intrusions, whereas in the more chronic the other studies. They found no differ-
American sample a critical attitude was ences between low and high EE relatives on
more uniquely associated with critical be- their use of negative or neutral codes, but
havior. A study is in progress to assess low EE relatives showed more positive be-
whether different types of neutral intru- haviors (n = 25, t = 2.64; P < 0.05) such
sions are associated with critical as com- as approval, agreement, smiling, and hu-
pared with overinvolved attitudes. mor. This suggests that low EE relatives
Another interesting finding in Strachan have the potential to be more supportive
et al. 's work was that in dyads where the rel- than high EE relatives in some situations.
ative was high EE both the relative and the Overall, these studies suggest that inter-
patient used more words than in dyads actions with high EE relatives can be char-
where the relative was low EE. These fin- acterized as calmer, less verbal, with more
dings suggest that in high EE dyads both pauses, and more positive support.
participants are actively involved in the in- Although there is a reasonable level of
teraction, rather than the relative being comparability between attitudes expressed
dominant and the patient submissive. These in the Camberwell and affective style ex-
findings are similar to those reported by pressed interactionally, the distributions
Kuipers, Sturgeon, Berkowitz, and Leff revealed that the correspondence is far
(1983) who observed relatives and patients from perfect. The majority of high EE par-
talking to an interviewer and found that ents, defined as critical on the Camberwell,
high EE relatives spent 57% more time are indeed expressive of criticism but others
talking than low EE relatives, a percentage express none at all. Thus, some high EE
which is very close to the 61 % higher word parents are congruent across situations and
count observed here. Further, they found others appear to dampen or inhibit these
that the amount of silence was significantly high EE attitudes when in direct confronta-
longerin low EE pairs than in high EE pairs. tion with the patient. Currently, we are in-
Strangely enough, none of these studies vestigating whether patients living with
showed that low EE relatives made signifi- high EE individuals who express these nega-
cantly more supportive statements during tive affective attitudes when interacting
the interactions, although there were trends directly with the patient are more relapse-
in the predicted direction. This may have prone than those patients with relatives
been because the discussions focused who have the negative attitudes but do not
around emotionally charged issues and elic- express them directly to the patient.
ited critical and intrusive statements. Dis-

Patient Attributes Associated with EE Status


We mentioned earlier that Brown et al. tion since. If high EE attitudes are associat-
(1972) indicated that certain patient char- ed with relapse, is it not possible that this is
acteristics were associated with both high due to a correlation with a third variable,
EE attitudes and subsequent relapse as such as the severity or quality of patient
well. However, the patient's contribution symptomatology at the time of hospital dis-
to the affective climate of the family follow- charge? Leff (1976) reported negative data
ing hospitalization has received little atten- in this regard when psychiatrists' ratings of
Do Relatives Express Expressed Emotion? 57
the severity of symptoms at discharge were level. The coping style codes covered three
examined. broad categories of self-statements express-
A similar analysis of symptom ratings, of ed by a patient: positive, negative, and auto-
the sample from the Falloon study (Miko- nomous. Positive self-statements refer to
witz, Goldstein, and Falloon, 1983), re- statements of worth or pride in some activi-
vealed parallel findings to those reported by ty or attribute of the patient. Negative self-
Leff. There were no significant differences statements are self-critical remarks, and
between patients from high or low EE autonomous statements reflect assertions
homes on the Present State Examination by the patient to follow some self-selected
(PSE; Wing, Cooper, and Sartorius, 1974) path of action.
rated during the most acute phase of the Data analyzed so far have revealed that
current episode, on the Brief Psychiatric patients from high and low EE homes differ
Rating Scale (BPRS; Overall and Gorham, markedly in the rate of negative and posi-
1962) obtained shortly before discharge, tive self-statements. As hypothesized, pa-
nor in the number of prior hospitalizations. tients from high EE homes express a signifi-
There were also no differences in ratings of cantly higher number of negative self-state-
premorbid adjustment on the UCLA social ments and a lower number of positive self-
attainment scale (Goldstein, 1978). The lat- statements than patients from low EE
ter is particularly important as premorbid homes (P < 0.001). Possibly, the sense of
adjustment is an established prognostic in- ineptitude expressed by these negative self-
dicator, and it is important to demonstrate statements may be particularly infuriating
its independence from EE attitudes. to relatives who see them as one more sign
Miklowitz et al. (1983) did find, however, of the frustrating negative symptoms of the
that patients from one high EE subgroup, disorder.
the emotionally overinvolved subsample, To date, our analyses of parent and pa-
had poor premorbid adjustment and high tient interactive behaviors have been car-
levels of residual symptomatology at dis- ried out independently. Yet, to understand
charge. However, patients whose high EE better the patterns of intrafamilial trans-
relatives were defined by highly critical at- actions in families varying in EE attitudes,
titudes were indiscriminable from patients future research must integrate these two
from low EE families in terms of their level levels of data (see also Chap. 7). Thus, cur-
of residual symptomatology and premorbid rent research in our laboratory is designed
adjustment. to further our understanding of how patient
Symptoms and permorbid adjustment do behaviors trigger relatives' emotional re-
not exhaust the personal qualities of a schi- sponses and, conversely, to identify those
zophrenic individual that can arouse high behaviors emitted by relatives which trigger
EE feelings in a relative. Possibly some negative social reaction by the patient.
other more subtle aspects of the schizophre- Thus, sequential analyses are being used to
nic's behavior arouse critical or overin- determine whether patient's self-denigrat-
volved feeling in a close relative. Currently, ing remarks trigger parental criticism and
we are investigating whether there are cer- intrusiveness or whether they represent re-
tain key behaviors emitted by the schizo- actions to these parental behaviors. A com-
phrenic during the direct interaction task prehensive analysis of the manner in which
which trigger criticisms or intrusiveness by a family relationships have an impact on the
parent. course of schizophrenia requires an appre-
In a study currently underway, a coding ciation of the subtle reciprocities in these
system (the coping style scale) was applied families and the manner in which the level
to the same transcripts which had previous- of tension within the home escalates or de-
ly been scored for affective style. This scor- escalates because of such interactive pro-
ing was done by raters blind to the AS scor- cesses.
ing done previously and to the parental EE
58 A. M. Strachan et al.
References
Brown, G. W., Birley, J. L. T., and Wing, J. F. Miklowitz, D. J., Goldstein, M. J., and Falloon,
(1972). Influence of family life on the course of I. R. H. (1983). Premorbid and symptomatic
schizophrenic disorders: A replication. British characteristics of schizophrenics from families
Journal of Psychiatry, 121,241-258. with high and low level of expressed emotion.
Brown, G. W., and Rutter, M. (1966). The Journal of Abnormal Psychology, 92, 359-367.
measurement of family activities and relation- Miklowitz, D. J., Goldstein, M. J., Falloon, I. R.
ships: A methodological study. Human Rela- H., and Doane, J. A. (1984). Interactional cor-
tions, 19,241-263. relates of expressed emotion in the families of
Doane, J. A., West, K. L., Goldstein, M. J., schizophrenics. British Journal of Psychiatry,
Rodnick,E. H., andJones,J. E. (1981). Paren- 144,482-487.
tal communication deviance and affective style: Overall, J. E., and Gorham, D. R. (1962). The
Predictors of subsequent schizophrenia spec- brief psychiatric rating scale. Psychological
trum disorders in vulnerable adolescents. Report, 10, 799.
Archives of General Psychiatry, 38, 679-685. Rutter, M., and Brown, G. W. (1966). The relia-
Goldstein, M. J. (1978). Further data concerning bility and validity of measures of family life and
the relation between premorbid adjustment relationships in families containing a psychia-
and paranoid symptomatology. Schizophrenia tric patient. Social Psychiatry, 1, 38-53.
Bulletin, 4, 236-243. Strachan, A. M., Leff, L. P., Goldstein, M. J.,
Goldstein, M. J., Judd, L. L., Rodnick, E. H., Doane, J. A., and Burtt, C. (1985). Emotional
Alkire, A., and Gould, E. (1968). A method attitudes and direct communication in the fami-
for studying social influence and coping pat- lies of schizophrenics: A cross-national replica-
terns within families of disturbed adolescents. tion. Manuscript submitted for publication.
Journal of Nervous and Mental Disease, 147, Valone, K., Norton, J. P., Goldstein, M. J., and
233-25l. Doane, J. A. (1983). Parental expressed emo-
Goldstein, M. J., Rodnick, E. H., Evans, J. R., tion and affective style in an adolescent sample
May, P. R. A., and Steinberg, M. R. (1978). at risk for schizophrenia spectrum disorders.
Drug and family therapy in the aftercare of Journal of Abnormal Psychology, 92, 399-407.
acute schizophrenics. Archives of General Psy- Vaughn, C. E., and Leff, J. P. (1976a). The mea-
chiatry, 35,1169-1177. surement of expressed emotion in the families
Greenwald, D. P., Kornblith, S. J., and Hop- of psychiatric patients. British Journal of Clini-
kins, J. (1980). Behavioral Assessment of Fami- cal and Social Psychology, 15, 157-165.
lies of Schizophrenics: A Validity Study of Ex- Vaughn, C. E., and Leff, J. P. (1976b). The in-
pressed Emotion. Paper presented at the 14th fluence of family and social factors on the
Annual Convention of the Association for the course of psychiatric illness: A comparison of
Advancement of Behavior Therapy, New schizophrenic and depressed neurotic patients.
York, November. British Journal of Psychiatry, 129, 125-137.
Kuipers, L., Sturgeon, D., Berkowitz, R., and Vaughn, C. E., Snyder, K. S., Jones, S., Free-
Leff, J. (1983). Characteristics of expressed man, W. B., and Falloon, I. R. H. (1984).
emotion: Its relationship to speech and look- Family factors in schizophrenic relapse: A Cali-
ing in schizophrenic patients and their rela- fornia replication of the British research on Ex-
tives. British Journal of Clinical Psychology, pressed Emotion. Archives of General Psychi-
22,257-264. atry,41,1169-1177.
Leff, J. P. (1976). Schizophrenia and sensitivity Wing, J. K., Cooper, J. E., and Sartorius, N.
to the family environment. Schizophrenia Bul- (1974). The description and classification of
letin, 2, 566-574. psychiatric symptoms: An instruction manual
Leff, J. P., and Vaughn, C. E. (1981). The role of for the PSE and CATEGO system. London:
maintenance therapy and relatives' expressed Cambridge University Press.
emotion in relapse of schizophrenia: A two-
year follow-up. British Journal of Psychiatry,
139, 102-104.
5. Short-Term Relapse in Young Schizophrenics:
Can It Be Predicted and Affected by Family (CFI) ,
Patient, and Treatment Variables?
An Experimental Study*
B. Dulz and I. Hand

The Hamburg Schizophrenia and CFI Project


The Hamburg Schizophrenia and CFI Pro- replication of the Anglo-American CFI stu-
ject evolved from an attempt by various aca- dies in a German-speaking culture. At the
demic and nonacademic members of the same time, with our diagnostic and treat-
Psychiatric University Clinic to develop ment interventions, we wanted to investi-
more reliable and effective means for pre- gate what the "meaning" of the published
dictive assessment and treatment of young- results and of our own CFI results could be
er, mainly first- or second-breakdown schi- for a conceptualization of the findings that
zophrenic patients at high risk for a chronic until then had been purely empirical. Much
course of illness. We decided to work with dispute had occured and still seems to be
younger schizophrenics as there had been going on about whether or not the CFI liter-
much less systematic treatment research ature implicitly "blames" the relatives for
performed with them than the more chronic the patients' relapse and illness. Research-
conditions. ers investigating expressed emotion (EE)
The development of our research design felt themselves misunderstood by these cri-
(Hand and Kottgen; details in Hand and tics. Yet, they themselves had not made
Gross, 1980) was strongly influenced by the clear whether high EE-related behaviors of
following sources: relatives were supposed to "cause" relapse
1. The results published concerning ex- of psychosis or vice versa. Does the assump-
perience with the Camberwell Family tion of a behavioral feedback loop really
Interview (CFI) (extensive literature re- answer this question?
views by Hooley, Chap. 2, and Vaughn, We shall first summarize the main aims of
Chap. 8, this volume) and direct support this project and some general data on out-
from C. Vaughn and K. Snyder regard- come before turning to our detailed ana-
ing the training of raters lyses of relapse and the variables that pos-
2. The frank and stimulating presentations sibly contribute to relapse.
and discussions of the schizophrenia re-
search groups participating in the 1979
Replication of Previous CFI Results and
conference of the Society for Psycho-
Direct Evaluation of the CFI
therapy Research in Oxford, England
3. The results of the three major long-term The main intentions of the following inves-
studies in German-speaking countries tigations were to replicate previous CFI re-
(Bleuler, 1972; Ciompi and Miiller, sults and to directly evaluate the CFI.
1976; Huber et aI., 1979) on the course Replication of previous CFI results con-
of schizophrenia over decades sisted of:
4. The continuous flow of information
from the ongoing research work of R. * This project was supported by the Deutsche
Liberman and his colleagues in Camaril- Forschungsgemeinschaft, Sonderforschungsbe-
lo and Los Angeles. reich 115, Project B 23, University of Hamburg
Within the context of our study, we con- (main study) and by the Charles Hosie Founda-
ducted the first and so far only attempt at tion, Hamburg (pilot study).
60 B. Dulz and I. Hand
Identification of the proportions of high more critical than nonobsessional?) and
EE relatives in younger schizophrenic in (b) the patients (do specific neurotic
patients in a German-speaking culture. symptoms or traits in patients specifical-
Comparison of relapse rates in patients ly correlate with high scores in EE scales
from high EE and low EE families. of their relatives?).
Comparison of relapse rates in patients
from high EE families who either did or
Indirect Evaluation of the eFI:
did not receive regular medication and
Group Therapy for Patients and Relatives
who did or did not participate in group Separately
therapy.
Direct evaluation of the CFI consisted of: According to the CFI literature in the late
Assessment of the stability of initially 1970s, "immunization by neuroleptic medi-
high and initially low EE ratings over cation" (of the patient) and reduction of
time (no such investigation had been face-to-face contact between the patient
published at the start of this project). If and high EE family members (less than
high EE ratings (in relatives) at the time 35 hlweek seemed to be powerful means of
of the patient's discharge do predict re- protecting vulnerable patients from re-
lapse (in patients) 9 months later, one lapse-inducing, high EE-related behaviors
ought to expect some kind of causal in- of their relatives. (It ought to be remem-
teraction and, hence, stability of high bered here that this causal attribution was
EE ratings over this period of time. implicit in most of the studies available until
Comparison of global EE ratings over the late 1970s.) These interventions seemed
time with ratings on the EE subscales of easy to administer and were the most fre-
emotional overinvolvement (EOI) , criti- quently applied.
cism, and hostility. All published studies Surprisingly, most of the CFI-related tre-
attribute a high EE "total" score to a rel- atment studies in those years employed
ative as soon as she or he has reached long-term neuroleptic medication and only
high ratings on at least one of the EE short-term psychosocial treatment (often
subscales. Yet, there is no published evi- only on an inpatient basis). Assuming that
dence that these subscales are directly family and social learning factors have a
related to a basic, unifying concept. If major impact on the course of schizophre-
ratings over time on these subscales nia, one would rather have expected the re-
were not correlated or went into oppo- verse proportion of both treatment ingre-
site directions, this would not necessarily dients - medication for patients as intermit-
question the clinical usefullness of the tent crisis intervention and psychosocial
EE total score as a "melting pot" for dif- treatment as the long-term stabilizer.
ferent relapse-related variables but it As far as the psychosocial treatments
would certainly question its "meaning" themselves are concerned, they did not
as a construct. seem to systematically use interventions
Comparison of reepeated assessments derived from information gathered with the
over time of EE ratings and nuclear CFI.
symptoms (according to the Present In recent years, there has been a major
State Examination, PSE). Only such an change in the content of CFI-related treat-
analysis of correlations over time can ment programs. A variety of approaches to
produce empirical evidence for a con- directly affect negative family interactions
ceptualization of the CFI that may stop are now being investigated: (a) social skills
the arguments about the "meaning" of training groups for patients (Liberman,
CFI results obtained in the "classic" way Wallace, Vaughn, and Snyder, 1980; Wal-
(EE at discharge, relapse at the 9- lace, Vaughn, and Snyder, 1982), (b) "psy-
months follOW-Up). choeducational" groups for relatives, in
Comparison of EE ratings and self-rat- combination with family sessions (Ander-
ings of multiple neurotic symptomatolo- son, Hogarty, and Reiss, 1980), (c) rela-
gy and neurotic traits over time in (a) the tives' groups, with a main focus on CFI-
relatives (e.g., are obsessional relatives derived themes to achieve reduction of high
Short-Term Relapse in Young Schizophrenics 61
EE-related attitudes and behaviors (Berko- other skills in patients and relatives, and (e)
witz, Kuipers, Eberlein-Vries, and Leff, offer training in recognizing the occurrence
1981), (d) mixed relatives' groups with high of schizophrenic symptoms such as an ex-
and low EE members in an attempt to em- pression of the illness, an attempted coping
ploy low EE relatives as co-therapists in response for more severe (e.g., social) de-
teaching skills for coping with schizophre- ficits, and an "interactional maneuver."
nia to family members with high EE ratings Additionally, basic information about
(Leff, Kuipers, and Berkowitz, 1979), and the illness of schizophrenia was given. In
(e) treatment of the single family unit in its contrast to the "psychoeducational" ap-
natural environment emphasizing CFI-re- proach, the delivery of "knowledge" to pa-
lated themes (Falloon, Boyd, and McGill, tients and relatives was tried in a much less
1984). directive manner, spaced over much longer
In our design, we (Hand and K6ttgen, in periods of time, with smaller amounts of in-
Hand and Gross, 1980) decided to try yet formation to be digested in a given session,
another approach, indirect family therapy: and with more room for the patients to in-
The families were treated in separate fluence the structure and content of the
groups for patients and their relatives with treatment session.
the same therapists treating those groups The treatment plan is described in some
into which the members of each single detail by K6ttgen, S6nnichsen, Mollen-
family had been separated. In half of these hauer, and Jurth (1984). This final strategy
families, the patients received "high-inten- was developed on an eclectic-psychodynam-
sity" (HI) treatment weekly group sessions) ic basis derived from the cooperation and
and their relatives a corresponding "low- close mutual supervision of the therapist
intensity" (U) treatment (monthly group dyads (for each treatment group) composed
sessions); in the other half, the reverse ap- of therapists from the project and from the
plication of group treatments was made. hospital. It was not possible to develop the
Treatment was entirely on on outpatient originally intended, structured behavioral
basis and was meant to go on for 2 years. therapy program. It was also not possible to
CFI-derived information provided the main continue the project for the originally plan-
themes, both in the patient's and relatives' ned 6-years period.
groups.
It was hoped that a comparison of the General Design and Overall Outcomes
outcome in the patient-centered group
therapy would allow evaluation of the fol- One-hundred and twenty patients were re-
lowing questions within one single study: ferred from two hospitals based on admis-
Can high EE ratings be directly affected by sion interviews as part of the project. Crite-
intensive group treatment of relatives, and ria for inclusion were: nuclear symptoms
how does this affect patients? (PSE) exhibited during the month before
Can patients and their course of illness be admission; age, 18-30 years; totallength of
directly changed by intensive treatment, previous inpatient treatments no longer
and how does this affect high EE ratings in than 1 year; maximum number of previous
their relatives? hospital admissions, 3; key relative willing
Are separate group treatments for patients to participate in assessments and, if offered,
and their relatives a helpful and economical treatment. The results of the application of
means of treating families with problematic these selection criteria are shown in Fig-
or traumatic interactions? ure 1. Only 13% of the originally referred
The main treatment aims originally were sample eventually received treatment.
to (a) reduce (interactional) vulnerability in Originally, 52 patients and their 79 rela-
the patient, (b) reduce harmful (interac- tives were included in the project (further
tional) events in daily life, in particular from reduction of participants, cf. p. 64). An at-
high EE-related attitudes and behaviors in tempt was made to secure complex assess-
relatives, (c) reduce patients' behaviors that ments of patients and relatives: with self-ra-
might cause or maintain high EE behaviors ting scales on psychotic and mUltiple neurot-
in their relatives, (d) increase coping and ic symptomatology, personality, social
62 B. Dulz and I. Hand

1. Admission interviews
1 120 1
Excluded
22
tor" other reasons"

2.PSE Excluded
46
PSE

3. CFI

4. Design 29 23
(49reL) (30 reL)

EE + EE-

15 EE + 14 22
1 EE-
(16 tam.; 29 reL) (21 reL) (29 reL)

EE + EE-

Patient Relatives
groups groups

Fig. 1. Selection of patients and relatives.


Short-Term Relapse in Young Schizophrenics 63
skills and deficits, and socioeconomic de- tient and relative to the last to form a group.
velopment. Structured interviews were The patients had a mean age of 23
done with the PSE, CFI, and a relapse que- (18-30), their relatives of 53 years. Two-
stionnaire. Except for the PSE and CFI, an thirds of the relatives interviewed were
attempt was made to perform most assess- mothers, and two-thirds of the parents were
ments with both the patients and relatives. still married.
Assessment intervals, except for relapse The results for patients and relatives with
(first follow-up after 9 months), were plan- most of these assessment instruments are
ned as usual: during admission and 6, 18, reported in detail by K6ttgen et al. (1984) as
and 30 months after discharge. The CFI was well as a direct comparison with the previ-
assessed with the abbreviated version by ous studies in London (Vaughn and Leff,
Vaughn and Leff. A family was rated as 1976) and Los Angeles (Vaughn et al.,
high EE when at least one relative scored 4 1984). As differences may be important for
or 5 on EOI and made six or more critical a discussion of our results, some are sum-
remarks. One project rater (C. K6ttgen) marized here (LO = London; LA = Los
received CFI training with C. Vaughn and Angeles; HH = Hamburg):
K. Snyder. She then trained two other rat- Percentage of families where both parents
ers in the project. For 12 families, interrater were interviewed:
reliability between her and one of the ad- LO 27; LA 52; HH 38
ditionally trained raters was reported to be Percentage of parents in total sample:
high (r = 0.95). LO 46; LA 94; HH 85
Of the 16 patients who received treat- Percentage of high EE families:
ment, only 3 were female. Of the 26 rela- LO 57; LA 67; HH 56
tives, 14 were mothers, 10 fathers, and 2 Percentage of male patients:
siblings. All relatives of high EE families LO 41; LA 77; HH 65
were offered participation in the treatment Percentage of first admissions:
program (if they were low EE themselves, LO 57; LA 17; HH 69 (first and second ad-
they are called low EE co-relatives in the missions together: 92!) Percentage of re-
subsequent analyses). Allocation to high- lapse in EE+: EE- families:
or low-intensity treatment groups was LO 48:6; LA 56:17; HH 41:57!
mainly influenced by the sequence in which The EE and relapse results in our own study
patients were referred to the project. Be- here differ slightly as we - unlike K6ttgen
cause of the loss of families due to the vari- et al., but similar to the L.A. study - did
ous selection steps, it often took months not include the patients with "persisting
from identification ofthe first "suitable" pa- symptoms" in all the analyses.

Experimental Results
We shall start our analyses of predictor vari- lapses at the 9-month follow-up and their
ables for the course of schizophrenia (re- correlation with single EE ratings at the
lapse) with the family variables from the time of the patients' discharge. This will be
CFI, to be followed by the patient variable folowed by a series of analyses with repeat-
"nuclear symptoms" (NS) and the treat- ed assessments of EE variables (at dis-
ment variables "medication" and "group charge and the 6-month follow-up, CFI-
treatments." Finally, results from a combi- FU), eventually again related to relapse
nation of two to five variables for predic- rates (at the 9-month follow-up, REL-FU).
tions of relapse will be presented.
"Classic" EE Assessment and Relapse
Family Variables
Relapse Rates at the 9-Month Follow-up:
Before investigating the CFI variables in Control and Treatment Groups Combined
detail, we will first present results with the
"classic" CFI analysis: assessment of re- The course of illness in our patient sample is
64 B. Dulz and I. Hand
summarized in Table 1. We formed then matology was not defined as relapse when
three categories of "no relapse," "relapse," the private and (or) professional life of the
and "special course': As the operationaliza- patient was not affected by the sympto-
tion of relapse in the literature on schizo- matology.
phrenia is still a largely unresolved prob- Table 1 does not include the data of four
lem, we decided to use criteria similar to patients (which are included in the publica-
those described by Vaughn et al. (1982). tion by Kottgen et al., 1984), as these pa-
The six criteria which constitute the three tients had moved away and information had
main courses of illness in Table 1 are: come only from their relatives. The remain-
la: No psychotic symptomatology since ing 48 patients include those 5 from cate-
discharge from the hospital; Ib: psychotic gories 5 and 6 ("special course") who will be
symptomatology without deterioration in excluded from all those subsequent analy-
the quality of daily life, maximum duration ses that rely on follow-up data (resulting in
of 1 week, with or without hospital admis- a n of 43). Category 5 was reached by three
sion; lc: intermittent, short-term psychotic an n of 43). Category 5 was reached by three
symptomatology without deterioration of female patients who had not been discharg-
the quality of daily life. ed from the hospital during the REL-FU.
2a: Psychotic symptomatology without The two patients in category 6 had commit-
nuclear symptoms, for longer than 1 week, ted suicide while on the waiting list for their
without hospital admission; assigned project group.
2b: nuclear symptoms in addition to 2a. The overall outcome of approximately
3a: Readmission to the hospital for more 50% relapse in young schizophrenics during
than 1 week, but no nuclear symptoms; 3b: the first 9 months after discharge is in ac-
3a with nuclear symptoms. cordance with previous reports in the litera-
4: Persisting symptoms with deteriora- ture.
tion of the everyday quality of life.
5: Hospitalization for more than 50% of EE at Discharge and Relapse at the
the follow-up time. 9-Month Follow-up
6: Suicide. Of all our patients from the relapse cate-
Relapse was defined with regard to its in- gories 1-5 (n = 46; cf. Table 1), 25 (54%)
dividual as well as social relevance. Hospi- had relapses. The relapses occured in 14 of
tal readmission of less than 1 week is inter- the 29 (48%) patients with high EE rela-
preted as one means of preventing relapse tives, but - contrary to all previous publica-
in a short-term psychotic crisis. Likewise, tions - even in 11 ofthe 17 (65% ) from low
intermittent short-term psychotic sympto- EE families.

Table 1. Relapse rates at the 9-month follow-up: control and treatment groups combined.

Relapse
category n % n %
1a 16 33
21 43 No relapse
1b,c 5 10
2a,b 3 6
3a,b 13 27 22 46 Relapse
4 6 13
5 3 6
5 10 Special course
6 2 4
48 48
Short-Term Relapse in Young Schizophrenics 65
Course of EE Ratings over Time cause any of the EE+ patients could score
initially low on one of the two subscales.
In all subsequent analyses and figures with On the EE score, 16 of 33 initially high
EE results, we shall first report the "total" EE relatives scored low at FU, whereas
EE score (EE), followed by the results on only 5 of 30 initially low EE relatives
the subscales of emotional overinvolve- changed to high ratings at FU. Only 8 of all
ment (EOI) and criticism (CRIT). The sub- these relatives were spouses, 7 of whom
scale of hostility is not included as relatives scored low on both occasions.
never reached the cutoff point for a high Results on the total EE score resembled a
score. Simultaneously high ratings on EOI labile, state-like quality of high EE and a
and CRIT at the first assessment were only rather stable, trait-like quality of initially
observed in 4 of 63 relatives; one remained low EE ratings. The EOI and CRIT scales
high at FU only in CRIT, two scored low on showed almost identical developments of
both scales, and the fourth did not partici- ratings over time, with a particularly high
pate in the FU. stability of low EOI ratings.
Course of EE Ratings over Time Course of EE Ratings over Time:
Treatment and Control Groups Combined Control Groups
The results on all scales together are shown Whereas in the treatment groups all rela-
in Table 2: 63 relatives of 46 patients partici- tives participated in both CFI ratings, the
pated in admission interviews as well as in control groups, in particular the one with
CFI-FU. Of these 63,46 relatives came from low EE relatives, showed a much lower re-
high EE families. These 46 included 13 low test compliance: 12 of 29 (41 %) of the low
EE co-relatives from families with at least EE relatives and 3 of 21 (14%) of the high
one high EE relative. Therefore, the EE+ EE relatives refused to participate in the
ratings in Table 2 are from a total of 33 rela- second assessment. Understandably, retest
tives (46 minus 13), whereas the EE+ ra- compliance is higher in treated than in un-
tings are from 30 relatives (17 from the low treated persons, but it does not appear to be
EE control group and 13 from low EE co- as obvious as to why the dropout rate was so
relatives of high EE families). This differen- much higher in the low EE relatives.
tiation cannot be made in both subscales be-

Table 2. Course of EE ratings over time: treatment and control groups combined.

2nd CFI

EEscales
+ -

EE+ 17 16 33
EE- 5 25 30 EE
total score
63

EOI+ 7 8 15
EE
EOI- 2 46 48 emotional
overinvolvement
63

CRIT+ 10 12 22
EE
CRIT- 8 33 41 criticism
63
66 B. Dulz and I. Hand
Table 3. Natural course ofEE ratings over time: control group (high and low EE groups separately).

2nd CFI

EEscales
+ -
EE+ 6 7 13 HighEE
[EE-] 2 3 5 control grp.
EE
total score
EE- 2 15 17 LowEE
controlgrp.

EOH 2 2 4 HighEE
EOI- 1 13 14 control grp. EE
emotional
EOI- 0 17 17 LowEE overinvolvement
controlgrp.

CRIT+ 3 6 9 HighEE
CRIT- 2 7 9 control grp.
EE
CRIT- 2 15 17 LowEE criticism
control grp.

Table 3 shows the results for the high EE tives on all three scales surprisingly did not
and the low EE control group separately. show a specific treatment effect (in both
The low EE co-relatives of high EE families conditions, some 50% of initially high scor-
are now separated (the separation being in- es were low at FU, whereas low scores
dicated by brackets around EE- ratings) showed little change). Paradoxically, the
from the low EE relatives in the low EE CRIT ratings even seemed to indicate a
control group. We introduced this addition- beneficial control group effect. In the low
al subgroup, as we wanted to investigate EE co-relatives, two of eight became high
whether low EE co-relatives resemble more in the treatment groups compared with two
their high EE counterparts or the low EE of five in the control groups (Table 4).
control group in the course of ratings (cf. Comparison of high-intensity groups for
p.74). relatives (HI rel.), with 23-26 treatment
At CFI-FU, 7 of 13 initially high EE rela- sessions offered to participants, and low-in-
tives scored low, whereas only 2 of the ini- tensity groups for relatives (LI rel.), with
tially 17 low EE relatives had changed in the 8-24 sessions offered, showed no differ-
reverse direction. Results in the untreated ences between groups, and both resembled
control groups thus resembled those from the results reported before on the total EE
the total sample. The same holds true for scores.
the EOI ratings. The scale for CRIT even However, as Table 5 indicates, HI rel.
showed a decrease of high scores in two- groups seemed to specifically affect ratings
thirds of the subjects (without treatment). in both subscales; while initially high EOI
Of the five low EE co-relatives, two ratings decreased in this group, initially low
changed to high ratings. CRIT ratings increased (the LI rel. group
did not show this effect).
Course of High EE Ratings over Time:
Treatment and Control Groups
Course of EE Ratings and Relapse
Direct comparison of treated (n = 20) and
untreated (n = 13) initially high EE rela- Since EE ratings at discharge did not prove
Short-Term Relapse in Young Schizophrenics 67
Table 4. Course of high EE ratings over time: treatment and control groups.

2ndCFI
Treatment groups Control groups

EEscales EEscales
+ - + -
EE+ 11 9 20 6 7 13 EE
total score
[EE-j 2 6 8 2 3 5
28 18 46

EOI+ 5 6 11 2 2 4 EE
emotional
EOI- 1 16 17 1 13 14 overinvolvement
28 18 46

CRIT+ 7 6 13 3 6 9
EE
CRIT- 4 11 15 2 7 11 criticism

28 18 46

to be useful predictors of relapse in our investigate EE ratings and relapse in high


study, we shall now investigate whether re- EE families (n = 46 relatives), both in treat-
peated EE ratings can increase the predic- ment and control groups (again including
tive power of this instrument. We shall first the low EE co-relatives separately under

Table 5. Course of high EE ratings over time: effects of high-intensity vs low-intensity relatives
groups.

2nd CFI
Treatment groups Control groups
(LI pat. groups) (HI pat. groups)

EEscales EEscales
+ - + -

EE+ 5 5 10 6 4 10 EE
3 1 4 5 total score
[EE-j 1 2
13 15 28

EOI+ 2 5 7 3 1 4 EE
emotional
EOI- 1 5 6 0 11 11 overinvolvement
13 15 28

CRIT+ 4 3 7 3 3 6
EE
CRIT- 3 3 6 1 8 9 criticism

13 15 28
68 B. Dulz and I. Hand
the total EE score), then in low EE families no relapse, but two-thirds changed to low
(n = 17 relatives). even when patients relapsed!
Results from High EE Families (Treatment Do such diverse developments of the
and Control Groups Combined): three EE scales over time question the va-
lidity of the (most commonly used) total
As already mentioned, some 50% of the score?
high EE relatives changed to low EE total
scores at FU, independently of relapses in Results from Low EE Families
patients. Initially low EE co-relatives re- (Control Group):
mained the same only when patients did not Of the 17 relatives in the low EE control
relapse; three of four initially low EE co- group (10 with a relapsed patient), 15 re-
relatives of the patients who relapsed mained the same at FU on all three scales.
changed to high EE. It is difficult to inter- The other two relatives, both with a re-
pret this result, as the initially low EE rela- lapsed patient, remained low in EOI, but
tives in the control group in the vast majori- became high in CRIT.
ty remained low, even when patients re-
lapsed (Table 6).
In contrast to high total scores, high EOI Patient Variables
scores showed a positive correlation be-
tween relapse and their development over Nuclear Symptoms and Relapse
time. Four of six initially high EOI relatives All seven patients with nuclear symptoms
remained the same at FU when patients re- (NS) at discharge (two) or at discharge and
lapsed, as compared with four of ten, when FU (five) "relapsed" during FU, five of
patients had suffered no relapse. Low EOI them with persisting symptoms (relapse cat-
ratings remained the same, independently egory 5).
of relapse. Of the 36 patients without NS at dis-
Results became even more inconclusive charge, 15 (42%) relapsed. Of the 21 pa-
with the CRIT ratings: high ratings changed tients without NS at discharge and no re-
to low in about 50% when patients showed lapse, only 1 developed NS at FU.

Table 6. Course of EE ratings over time: high EE families and relapse.

2ndCFI
High EE relatives of patients

Without relapse With relapse


EEscales EEscales
+ - + -

EE+ 10 9 19 6 7 13 EE
total score
[EE-] 1 9 10 3 1 4
29 17 46

EOI+ 4 6 10 4 2 6 EE
emotional
EOI- 1 18 19 2 9 11 overinvolvement
29 17 46

CRIT+ 6 6 12 3 6 9
EE
CRIT- 3 14 17 2 6 8 criticism
29 17 46
Short-Term Relapse in Young Schizophrenics 69
Of the 22 patients with relapse, about taken into consideration. In fact, 9 of 12 pa-
one-third (n = 8) showed no NS at dis- tients who relapsed in spite of CNM com-
charge and FD, the second third (n = 7) NS plained about side effects, whereas only 6 of
only at FD, and only the last third (n = 7) 11 who received CNM and did not relapse
NS at discharge or on both assessments. expressed the same complaint.

Treatment Variables Group Therapy and Relapse


Of the patients from high EE families, 7 of
Continuous Neuroleptic Medication 13 (54%) relapsed in the control and 5 of 14
and Relapse (36%) in the treatment groups. We shall
Continuous neuroleptic medication (CNM) now look at both treatment conditions sep-
was defined as a neuroleptic dosage com- arately.
parable to 100 mg Haldol Decanoat in High-intensity group treatment (HI pat.)
monthly intervals for at least over half of was given to eight patients in two groups.
the follow-up time (the majority of patients One of them only had the chance to attend
received depot neuroleptics, e.g., halo- 9 sessions, the others were offered between
peridol decanoate, independently of the 28 and 43 sessions. Five of these patients re-
project). mained without relapse. They as well as two
Although CNM compliance seemed to be of the three who relapsed attended more
much higher in patients from high EE fami- than 75% ofthe treatment sessions offered.
lies (17 of 26 = 65 %) - among those partic- Low-intensity treatment (LI pat.) was
ularly high in the treatment groups - than given to another eight patients in two
from low EE families (6 of 17 = 35%) me- groups. Of these, one refused treatment
dication did not seem to affect relapse rates and another one could not participate for
specifically. Fifty percent of the patients other reasons (both relapsed). Of the re-
with and without medication relapsed maining six, who were offered between 8
(Table 8). and 14 sessions, two relapsed. These two at-
Medication may show specific effects tended less than 50% of the sessions offered,
when their side effects are additionally but similarly so did three of the four who did

Table 7. Treatment intensity and relapse.

Group treatments
HI pat. group LI pat. group
(LI rei group) (HIrel group)

Relapse No relapse
+ - + -
i::'"<) >75% 2 5 0 1
§ i::'"
co
<) ·3co 50%-75% 0 0 0 0
!:i ~
0.. <50% 1 0 2 3
;:::
0
....
OJ) 3 5 8 2 4 6
..c::
......
.~ >75% 1 3 0 2
<) '"
<)
c..> .~
I:: co 50%-75% 2 2 2 0
.~
V
0.. p::: <50% 0 0 0 2
8
0
U 3 5 8 2 4 6
70 B. Dulz and I. Hand
not relapse (cf. Table 7, upper section). These fered. It appears that patients' compliance
short-term relapse data do not show better with treatment motivated their relatives to
results for high-intensity treatments (with participate regularly rather than the other
higher appointment compliance of patients) way around.
than for low-intensity treatments (with also
lower appointment compliance of patients). Multivariate Prediction of Relapse
As the relatives of LI pat. groups them-
selves were offered HI reI. groups., with As we have seen so far, the single variables
regard to family problems, this may have investigated in most analyses separated the
been a compensation: Every single family total patient sample into two or three al-
unit in both patient groups received the most equally sized subsamples - with the
same total amount of treatment. exception of the presence of NS "at dis-
If HI reI. groups were to have such a com- charge." Can the combination ofthese var-
pensatory effect, this could only be ex- iables enhance their predictive power?
pected from high compliance of the rela-
tives. As data in Table 7 (lower section) Relapse: Family and Treatment Variables
show, this was not the case.
Whereas most patients in HI pat. groups Neither CNM nor group therapy alone spe-
also showed optimum compliance and cifically affected relapse rates. If we regard
those in LI pat. groups showed low com- both together, a third variable, high EE,
pliance (i.e., they intensified by their com- implicitly (by design) affects the outcome.
pliance the separation of treatment condi- A look at the data of patients from high
tions by design), the relatives did not show EE families only (treatment and control
the same response pattern. We found that groups combined) reveals that 15 of them
in the HI reI. groups the four relatives of pa- had suffered no relapse, 9 of whom had
tients who did not relapse were equally been in treatment groups. Of the nine with
distributed to both extreme pools of com- and the six without group therapy, one-
pliance, whereas the two relatives of re- third in each condition had received no me-
lapsed patients showed medium compli- dication. Of the patients in group therapy,
ance. In the LI reI. groups, no relative at- there were only five who (together with one
tended less than 50% of the sessions of- relative) attended more than 50% of the
fered! Four of the eight relatives reached sessions offered, whereas four did not (cf.
medium, the other four optimum compli- Table 8).
ance. In the treatment groups, a combination
With regard to the single family units, it of EE+, CNM, and group therapy (Table
became clear that HI paULI reI. treatment 8) only prevented relapse in 6 of 11 patients.
produced by far the best compliance of This result seems to be even worse than for
both family members in the treatment of- patients from high EE families with CNM,

Table 8. Relapse: family and treatment variables.

I EE ratings
Patients with CNM Patients without CNM

Treatment Control Treatment Control


groups groups groups groups
+ + - n + + - n Total
+ 5 2 5 12 2 2 6 10 22
- 6 4 1 11 3 2 5 10 21
11 6 6 23 5 4 11 20 43
Short-Term Relapse in Young Schizophrenics 71
but without additional group therapy; in alone or in combination enhance predicta-
this group, four of six patients did not re- bility of relapse, what then can additonal
lapse. In the small subsamples of patients application of a patient variable ("no NS at
from high EE families without CNM, group discharge" , no NSd) bring about?
treatment was not revealed to have exerted No NSd and no CNM led to relapse in 9 of
a specific effect compared with no treat- 19 and no NSd with CNM in 6 of 17 patients.
ment at all. Of the five patients with no NSd and CNM
In the patients from low EE families, without side effects (SE) (ct. p. 69), only
CNM did not show any "protective" effect one relapsed. In all following analyses, we
regarding relapse rates; five of these six pa- shall only use CNM without SE as the me-
tients relapsed; on the other hand, only 6 of dication variable, as this outcome as well as
11 patients without medication relapsed. the analysis of side effects tentatively sup-
port the clinical impression of their rele-
vance.
Relapse: Family, Treatment, and Patient
Variables
Relapse
If neither family nor treatment variables
+ -
+ 4 11 15

- 21 10 31

25 21 46

All groups
Relapse / Relapse

+ - + -

+ 2 10 12 + 2 1 3

- 12 5 17 - 9 5 14

14 15 29 11 6 17

,/ All EE+ groups EE- control group

Relapse Relapse

+ - + -

+ 0 6 6 + 2 4 6

- 7 3 10 - 5 2 7

7 9 16 7 6 13

/ All therapy groups ~ EE+ control group

Relapse Relapse

+ - + -

+ 0 5 5 + 0 1 1

- 3 0 3 - 4 3 7

3 5 8 4 4 8
HI pat. therapy group LI pat. therapy group

Fig. 2. Prediction of relapse by Family Compliance Index (FCI) for all groups.
72 B. Dulz and I. Hand
Eleven patients had no NSd and group 2. Regular, high-potency neuroleptic med-
therapy, and only three relapsed. Six pa- ication at least during half of the obser-
tients had no NSd, CNM without SE, and vation time.
group therapy, and none of them relapsed. 3. No side effects of neuroleptic medica-
However, a fourth and possibly even a fifth tion.
variable may have influenced this outcome. 4. Regular participation in patients'
These six patients were from a total sample groups.
of seven, of whom two relatives participated 5. Regular participation in relatives'
regularly in group treatment; also, five of groups.
these six patients attended the HI pat. 6. If group treatment is not offered, use of
groups. Obviously, introduction of the pa- alternative treatment modalities (thera-
tient variable increased plurivariate pred- peutic hostels, etc.).
ictability of relapse. A high FCI was shown by 6 ofthe 16 high
Finally, we would like to suggest a multi- EE families in the treatment groups, and
variante "Family Compliance Index" (FCI) none of the respective patients relapsed. Of
for prediction of the course of illness from the 13 high EE families from the control
the compliance behavior of patients and group 6 showed a high FCI; two of the re-
relatives with regard to the treatment of- spective patients relapsed.
fered. This FCI consists of the following six Of the 19 low EE families, only 3 showed
variables, four of which have to be present a high FCI - again indicating the specificity
in families with group therapy offered and of low EE families. Two of these three pa-
three in those without such an offer to tients were among the 11 who suffered re-
achieve a "high" rating: lapse.
The results of the systematic application
1. Regular outpatient psychiatric treat- of FCI on our total patient sample and its
ment after discharge. subgroups is shown in Figure 2.

Summary and Discussion

Overall Results: Prediction of Relapse


ication) than LI pat.IHI reI. families; yet,
Of 46 mainly (92%) first- and second- relapse rates were identical. Within HI and
breakdown schizophrenic patients, 46% LI pat. groups, the low and high compliance
(56%, including those with persisting symp- patients again showed almost identical re-
toms) had relapsed at the 9-month follow- lapse rates. It should be remembered here
up. Relapses occurred in 58% of the high that these results refer to the effects of
(total n = 29) and 65% of the low (total n = "being under treatment," not to treatment
17) EE families. outcome! The patient variable of nuclear
Prediction of relapse with any single of symptoms (NS) had equally low predictive
the following family or treatment variables power when there was a negative rating at
appeared impossible: EE in single or discharge. However, persisting NS during
repeated assessments, continuous neuro- inpatient treatment invariably were cor-
leptic medication (CNM), and group treat- related with relapse.
ment for patients and for relatives. With or Prediction by a combination of variables
without any of these variables, relapse rates prooved hardly more satisfactory: a com-
were about 50%. The apparent, but statis- bination of relatives' and treatment variables
tically nonsignificant tendency for a treat- - EE, CNM, and group therapy - did not
ment effect (36% relapse in treated as com- result in lower relapse rates. In contrast, the
pared with 54 % in untreated high EE fami- results appeared odd, as group therapy did
lies) disappeared when HI and LI pat. not seem to have an additional effect to
groups were compared: the HI pat./LI reI. CNM in patients from high EE families,
families showed much higher treatment and in those from low EE families (who, by
compliance (with group sessions and med- design, did not receive group treatment)
Short-Term Relapse in Young Schizophrenics 73
CNM even seemed to make outcome worse The results do not support most of the im-
than no treatment at all. plicit assumptions in CFI research: High
Only the additional application of the pa- ratings decreased to low on all scales in
tient variable of NS (no NS at discharge, no most analyses in about 50% of the subjects
NSd) and the modification ofCNM to CNM - independently of relapse rates or treat-
without side effects (SE) seems to increase ments! They seemed to measure a state-like
predictability of relapse: of the six patients quality, the state-related variables remain-
who showed this combination of variables ing unidentified. Low ratings in the vast ma-
(EE+, CNM without SE, group treatment, jority remained stable (trait-like) over time
and no NSd), none relapsed. However, five on all three scales, with only about 10%
of these patients were also in the HI pat. changing to high scores.
groups; and of all six patients, both parents In comparison with high EE families, the
participated in relatives' groups (which only low EE families showed very distinct re-
happened in 7 of all 16 families with group sults: a lower compliance with FU appoint-
treatment). ments (59% as compared with 86% in high
From these results, we construed a Family EE control groups); a much lower FCI
Compliance Index (FCI) with six variables. (only 3 of 17 scored high, and this without
A high FCI indicated a low relapse rate in relapse prevention, 6 of 16 high EE families
high EE families, both with and without tre- with and 6 of 13 without group therapy
atment. It did not do so in low EE families! scored high, with low to zero relapses); fi-
This kind of plurivariate prediction of re- nally, patients from low EE families
lapse is only of limited practical value. So showed a higher relapse rate and lower
far, the CFI has been used as a predictor at compliance with medication (the latter
the beginning of outpatient aftercare (hospi- hardly being the cause of the first). Yet, as
tal discharge), whereas the FCI relies much K6ttgen et al. (1984) described, low and
more on (compliance) variables during out- high EE families did not differ in socio-
patient aftercare. Any prediction of an event economic variables.
that includes variables more closely related To complicate matters even further,
(in time and content) to this event is, of some of the more puzzling results with EE
course, bound to achieve better results - in subsamples are summarized. The two
with lower generalizability. Further, it can- subscales EOI and CRIT showed a very
not be concluded from such an assessment similar state-like instability over time (like
(FCI) whether a high score with a low re- the total EE scores) when ratings were ini-
lapse rate is a consequence of a treatment tially high; initially low ratings remained
variable (e.g., HI pat. groups as a "nuclear" low, particularly in EO!. Thus, there is no
treatment, around which the other inter- support for the assumption that drops in
ventions can be established) or whether an high EE total scores are due to drops in
as yet undetected "family health factor" CRIT rather than EOI (d. Chap. 8, this
(e.g., benign atmosphere, independent of volume).
EE) enabled all family members to respond On the CRIT scale, more high ratings
to any help offered - this health factor pos- changed to low in the control than in the
sibly being in itself sufficient enough to pre- treatment groups, and HI pat. groups even
vent relapse. Our results with the FCI in seemed to increase initially low ratings
treated and untreated high EE families (while reducing high CRIT, and even more
seem to support the latter hypotheses. high EOI). When patients developed no re-
lapse, some 50% of high ratings changed to
Specific Results: Direct and Indirect
low - but when patients relapsed, 66% be-
came low.
Evaluation of the CFI
On the EOI scale, there was a more direct
This is the only study so far that has tried to correlation of high ratings with relapse, the
systematically assess the course of ratings ratings remaining high in families with and
on three EE variables (EE, EO!, CRIT) turning low in families without relapse. Ini-
simultaneously and in relation to CNM and tially low ratings remained the same re-
CFI-derived group treatment. gardless of relapse. It appears difficult to
74 B. Dulz and I. Hand
subsume these divergent results under one relatives interviewed. A particularly im-
CFI concept. portant variable from previous studies
Ratings of the low EE co-relatives (of seemed to be the amount of face-to-face
high EE families) differed from the low EE contact between patient and relatives (>35
control group, as they - like the high rat- hlweek increasing relapse rates). Again,
ings of their high EE family members - this could not be reproduced in our study: in
seemed to correlate with relapse: three of the high EE families, some 50% had more
the four whose patients relapsed turned than 35 h contact; yet, around 40% relapsed
high in their EE. each in the high- and low-contact environ-
These small numbers certainly do not ques- ments. In the low EE families, 77% had low
tion the experimentally supported assump- contact, but nevertheless 69% of them re-
tion by K6ttgen et al. (1984) that the vast lapsed.
majority of low EE families of young schi- Could there be a relevant amount of er-
zophrenics may actually be high EE (if in- raneous CFI ratings, as there was only an
stead of one at least two family members interrater reliability test between the
are interviewed). However, taking into ac- "properly" trained CFI rater in the project
count all the specific outcomes in low EE and one of the two other raters she had
families in this study, the overall impression trained herself? This appears unlikely be-
is that low EE families are very special and cause of the very close cooperation between
not just "hidden" high EE families. all three raters throughout the whole pro-
Our relapse rates in low EE families seem ject.
to support notions that this group of fami- Could it then have mattered that 65% of
lies is inhomogeneous and includes a all and 81 % of the patients treated were
"burnt-out" type (cf. Chap. 8, this volume), male, whereas two-thirds of the relatives
with learned apathy and indifference to- interviewed were mothers and all CFI inter-
ward stressful life events. Too little positive viewers and main therapists (in the thera-
stimulation may occur for the patients of pist dyads) were female? Finally, if differ-
these families (cf. Chap. 6, this volume). ences in duration of illness were the decisive
Additionally, one may have to think of a factor for differences in EE and relapse re-
subgroup of "hypocritical" noncritical rel- sults (i.e., treatment effects), then it would
atives, who verbally cope and understand no longer appear clinically meaningful to
and nonverbally send opposite messages. give first- and second-breakdown schizo-
phrenics this diagnosis.
It follows that, at least for young "schizo-
Conclusions
phrenics" , more studies are needed with re-
The prediction of relapse and derivation of peated assessments over time of all varia-
optimal treatments for young schizophrenic bles regarded relevant, and more attention
patients remains an unresolved problem. should be paid to low EE families.
EE results in this study raise rather than The rather short duration of treatment
answer questions. Almost none of the cur- and FU, the loss of the majority of families
rent assumptions in the CFI literature could by the selection criteria, and compliance
be supported by our data. problems with assessment appointments
Reasons for our contradicting results and treatments severely restrict the con-
may be manifold: K6ttgen et al. (1984) have clusions that can be drawn for many of the
described in detail differences between our questions investigated. Unfortunately, pre-
patients' and relatives' samples and those in vious studies with other outcomes and con-
previous studies with regard to duration of clusions were hardly less affected by these
illness, age, sex, and type and number of problems.

References
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76 B. Dulz and I. Hand
Comment on Chap. 5*
C. Vaughn high persisting symptoms appeared to be
less responsive to social influence than
The Hamburg investigators admit to being other patients, perhaps because of a dif-
puzzled by their own results, which appear ferent type of schizophrenia, more biologi-
to refute the main findings of all EE-based cally based. Yet, the Hamburg investiga-
studies to date. None of the factors previ- tors included patients with high persisting
ously identified as offering a measure of symptoms in the "relapsed" group. Thus,
protection against schizophrenic relapse the allocation of patients to "relapse" and
did so in this study: neither regular medica- "no relapse" categories differed considera-
tion, nor relatives' low EE, nor family ther- bly from past practice. The broader out-
apy. Particularly surprising is the high rate come criteria employed in Hamburg are not
of relapse in the low EE group, irrespective necessarily inferior to a criterion of out-
of medication compliance. In previous stu- come which is narrowly defined, but they
dies, the rate of relapses for low EE patients are different and should not be viewed as
on regular medication has been negligible. equivalent. Meaningful comparisons with
These contradictory conclusions clearly previous results cannot be made in the ab-
warrant additional consideration and com- sence of comparable criteria.
ment. A second major difference concerns an
That this was a well-intentioned and care- unreported but crucial aspect of the Ham-
fully executed study is not in doubt. How- burg study: the fact that a majority of pa-
ever, there were major differences in the tients, and low EE patients in particular,
design and methodology of the Hamburg did not live at home throughout the follow-
study, vis-a-vis previous EE studies, which up period. Indeed, low EE patients were
made it less of a "replication" than one much more likely than high EE patients to
would have wished. These may be sum- live away from parents and to have low
marized as follows: face-to-face contact (Kottgen, 1984, per-
1. Differences in the relapse criteria used sonal communication). The failure of the
to define outcome Hamburg investigators to either acknowl-
2. Unreported differences in the propor- edge this fact or to allow for it in the collec-
tion of patients who were living contin- tion and analysis of data casts doubt on
uously at home during the follow-up pe- many of the conclusions concerning low EE
riod families and relapse. Results from the Cali-
3. Unreported differences in the proce- fornia EE study emphasized the impor-
dures used to allocate families to high tance of the "at-home" factor. In the Cali-
EE and low EE groups. fornia study, unlike earlier British studies, a
A fuller account of these differences may sizeable minority of the total sample lived
explain at least in part the discrepant results away from home for some part of the fol-
obtained. low-up period. Because the impact of the
Firstly, the Hamburg relapse criteria dif- key relatives might be "diluted" in these
fered in several important respects from cases (depending also on patterns of con-
those employed in earlier EE studies, de- tact), it was thought essential to consider
spite the author's claims to the contrary. the results for the at-home group separately
Past EE studies have used changes in spe-
cifically schizophrenic symptomatology to
define relapse, without regard to days spent * A copy of Chap. 5 was not available to Christine
in the hospital or quality of social function- Vaughn when she wrote her contribution to this
ing in the follow-up period. Furthermore, book. As results seem to question previous CFI
publications with regard to their generalizability
patients who never recovered from the key to young schizophrenics, we greatly appreciate
admission episode were excluded from sub- that she has accepted the invitation for her special
sequent analyses of the relationship be- comments. It was agreed beforehand that the
tween relatives' EE scores and their own re- authors would not comment upon these com-
lapse (Vaughn et al. 1984). Patients with ments in this volume.
Short-Term Relapse in Young Schizophrenics 77
from the rest of the sample. As reported ficient information. The households in que-
elsewhere (Vaughn, Snyder, Jones, Free- stion might well be high EE, and certainly
man, and Falloon, 1984), the relationship should not be treated as low EE. Such
between EE and relapse was predictably misallocations are likely to have contrib-
strongest for patients living at home con- uted to the increased rate of "relapse" in the
tinuously, although there was still a signifi- Hamburg low EE group.
cant relationship for the sample as a whole. In summary, there are a number of im-
However, the significant relationship disap- portant differences in design and methodol-
peared if one considered only the patients ogy between the Hamburg study and previ-
who lived away for some part of the follow- ous EE studies which call into question its
up period. High EE patients were more status as a "replication" study. It is neces-
likely to remain well if away from home, sary to look no further than these differ-
while low EE patients were more likely to ences for possible explanations of discre-
relapse. The interpretation of the low EE pant results regarding EE and relapse.
data was that the benign influence of the Other puzzling findings, such as the failure
low EE relative was diminished if the pa- of medication to protect patients against re-
tient lived away from home, with other re- lapse and the absence of a specific effect for
lationships and other stresses (including life family therapy, warrant a closer examina-
events) assuming increased importance. tion, which is beyond the scope of this com-
These results have important implications mentarv. However, the low levels of com-
for the Hamburg study. Given the high pro- pliance with family treatment may be parti-
portion of low EE patients living away from ally explained by the fact that many patients
home and exposed to various nonfamilial (especially low EE patients) lived away
influences, it seems quite unjustified to sug- from home, as well as by the clinicians' que-
gest that their high relapse rates may be due stionable decision to delay family therapy
to relatives who are "burnt-out" or "hypo- until the time when a treatment "group"
critical"! was complete. An approach in which pa-
A third major difference was the Ham- tients and relatives may wait weeks or even
burg decision to allocate to the low EE months for treatment to begin does not
group patients from households in which a seem to provide an optimal test of family
key relative who was not interviewed was therapy.
described by an interviewed low EE relative Finally, it is not an implicit assumption of
as being critical/hostile or overinvolved the CFI research that EE levels are constant
(Kottgen, 1984, personal communication). over time. This issue is discussed at some
This is not appropriate, even ifthe noninter- length elsewhere in this book (Chap. 8). In
viewed relative was in low contact with the most respects, the Hamburg results are con-
patient. In previous EE studies, such cases sistent with earlier findings concerning the
would have been dropped because of insuf- stability of EE.

References
Vaughn, C. E., Snyder, K. S., Jones, S., Free- plication in California of British research on ex-
man, W. B., and Falloon, I. R. H. (1984). pressed emotion. Archives of General Psychia-
Family factors in schizophrenics relapse: Re- try, 41,1169-1177.
6. Emotional Atmosphere in Families of Schizo-
phrenic Outpatients: Relevance of a Practice-
Oriented Assessment Instrument
G. Buchkremer, H. Schulze-Monking, L. Lewandowski, and C. Wittgen

Introduction
The Camberwell Family Interview (CFI), and Leff (1976 a) obtained with the CFI can
the measure used to assess "expressed emo- be replicated using a simpler measurement
tion" (EE), can hardly be used in routine instrument. An appropriate survey instru-
psychiatric work since the time required for ment, the Munster Familiy Interview
relatives and raters with this test instrument (Munsteraner Familienbogen, MFB), is de-
is very great (about 4-5 h per rating). In ad- scribed in this paper. This interview not
dition, the amount of effort necessary to ar- only provides a measure of the emotions ex-
rive at a sufficiently high interrater reliabili- pressed by the individual family members,
ty during rater training is hardly possible but also registers the entire emotional fami-
under the given conditions. ly atmosphere (EFA) and might therefore
For psychiatric practice, the question be an alternative measure of the EE con-
arises as to whether the results of Vaughn struct.

Method
expenditure of time than the CFI. By means
Munster Family Interview (MFB)
of this instrument, nine qualities of feeling
The MFB is a practicable survey instrument (EFA factors) in the emotional family at-
which requires both less rater training and mosphere are surveyed (Table 1).

Table 1. Emotional Family Atmosphere (EFA) Factors.

Hostility Statements of aggressive attitude toward patient, impatience


Criticism Comments of nonagreement with behavior or attributes of the patient
Overprotectiveness Tendency to take care of patient in overly concerned way, belief that
patient cannot take care of himself
Rejection Statements against the patient as a person, lack of any kind of empathy
Resignation Hopelessness that patient will get better, no impulse to improve
situation, pity
Acceptance Relative compliance with illness, patient with his problems accepted,
constructive criticism
Warmth Empathy, attachment, expression of affection
Indifference No interest at all in patient's matters, no inclination to support,
no empathy, laissez-faire attitude
Predominance Tendency to influence and control patient
80 G. Buchkremer et al.
The rating is performed by one or two months previously. The patients were thus
trained raters in the context of a home visit not receiving inpatient or partial inpatient
by a semistructured interview correspond- treatment at the time of the study. All of
ing to the CFI. The interview is conducted them were living in their family.
with the whole family, i.e., the patient as All family members, including the pa-
well as all relatives together. The evalua- tient, were rated during a home visit with
tion covers directly expressed feelings, re- regard to their emotional expressiveness
ports on feelings and behaviors from the re- (EFA factors). A mean value was calculat-
cent past, as well as other forms of emotion- ed for each emotional factor based upon the
al expression such as the sound ofthe voice, values of all the relatives present at the
mimicry, gestures, and bearing. A rating on home visit. These mean values were used as
a four-point scale is carried out with regard indicators of the emotional atmosphere of
to each EFA factor by raters who have been the whole family. In this way, a distortion is
trained in this procedure (it takes approxi- possible as when, for example, a highly crit-
mately 3 days to arrive at a sufficient inter- ical mother was present with an uncritical
rater agreement). father or siblings.
The test subjects on whom the MFB was Rating in the context of a home visit had
used and validated were from a research the further advantage that the interactions
project on relapse prevention in schizo- between the family members and the pa-
phrenic outpatients (cf. Buchkremer and tient could be observed in their natural sur-
Fiedler 1982). Twenty-four patients were roundings. In addition, the home visit
diagnosed as schizophrenic according to enabled the establishment of a strong and
ICD reference criteria. They had at least buoyant relationship between the relatives
two acute psychotic manifestations and and the therapist which was helpful in sub-
were checked in addition by an independent sequent therapy and motivated the relatives
expert with regard to the diagnosis of schi- to make themselves available for catamnes-
zophrenia. In addition, the last acute psy- tic investigations (Buchkremer and Lewan-
chotic exacerbation or the last hospitaliza- dowski 1984).
tion had to have occured more than 6

Results
For the EFA factors of criticism, over-
Reliability
protectiveness, and rejection, a good de-
Ten advanced psychology students were gree of reliability resulted, and for the EFA
trained for 24 h in the rating of the EFA fac- factors of hostility, resignation, predomi-
tors. The training was carried out using nance, and acceptance, a moderate degree
videotapes of family interactions. A loss of of reliability. Low Kappa coefficients were
information had to be accepted as the fami- calculated for the EFA factors of indiffer-
ly atmosphere can be experienced more viv- ence and warmth. For the reasons men-
idly during the home visit than on a video- tioned above, they were difficult to rate and
tape. In this way, the EFA factor indiffer- had only a low frequency of moderate or
ence and warmth were hard to rate since high degree rating but a good agreement.
their rating is especially based on nonverbal (In a study which is currently in progress, a
behavior which is difficult to assess from reliability check will be carried out in the
videotapes. context of home visits.)
Ratings of the EFA factors were done in-
dividually by each rater, and overall 18 fam-
Validity
ily members were rated. To test reliability a
dichotomy was used, contrasting a moder- Different aspects of the validity of the MFB
ate or high rating with a mild or "no evi- will be investigated below. According to the
dence" rating. The results are shown in results of Vaughn and Leff (1976 b), criti-
Table 2. cism, and to a small extent, emotional over-
Emotional Atmosphere in Families of Schizophrenic Outpatients 81
Table 2. Interrater Reliability of the EFA Factors (n = 18).

Kappa Agreement!

EFAfactors Mean SD Median Range Mean


Criticism 0.69 0.23 0.73 0.18-1.0 0.89
Hostility 0.41 0.35 0.44 0.00-1.0 0.93
Overprotectiveness 0.75 0.12 0.73 0.45-1.0 0.90
Rejection 0.66 0.20 0.64 0.31-1.0 0.94
Resignation 0.51 0.22 0.46 0.17-1.0 0.87
Indifference 0.09 0.04 0.00 -0.08-1.0 0.94
Acceptance 0.40 0.20 0.37 0.05-0.82 0.81
Predominance 0.56 0.15 0.56 0.28-0.85 0.80
Warmth 0.14 0.26 0.00 -0.15-1.0 0.83
1 Percentage of agreement between two raters.

involvement, were especially predictive of lapse criteria. A high measure of criticism


relapse over the course of 1 year. The ques- by the relatives is accompanied by an espe-
tion therefore arises as to whether these cially great danger of relapse in the patient.
same EFA factors were equally valid re- According to the results of Brown et al.
lapse predictors. (1972) and of Vaughn and Leff (1976 b),
To answer this question, three different emotional overinvolvement would also
and mutually exclusive relapse definitions have had to lead to the expectation of a
were chosen: raised risk of relapse. The English word
1. Rehospitalization (more than 2 days) or overinvolvement, i.e., emotional overin-
more than 5 days in a day clinic volvement, was translated in the definition
2. Outpatient treatment: sick leave due to of the MFB factor with the term "overpro-
psychotic symptoms, recommencement tectiveness." A change in meaning thereby
of neuroleptics, doubling of the dose of arose which might possibly explain the dif-
neuroleptics ference between the result of this study and
3. Subjectively experienced relapse that of the English authors. With regard to
A subjectively experienced relapse was the MFB factor, a prognostic validity is thus
the term used to designate a crisis situation not to be assumed. The EFA factor of in-
experienced by the patient, which could be difference, surprisingly, showed several
mastered without the aid of the psychiatrist. positive correlations with relapse criteria.
The results (Table 3) indicate that the These criteria were met in the course of 1
EFA factors of criticism and indifference year after therapy.
display significant correlations with the re-

Table 3. Phi Correlation Coefficients Between EFA Factors and Relapse on I-Year Follow-up
(n = 23)

Relapse Rehospitali- Psychiatric outpatient treatment Subjectively


zation Sick leave due Recommence- Doubling of experienced
EFAfactors to psychotic mentof the dose of relapse
symptoms neuroleptics neuroleptics

Criticism 0.44* 0.48** 0.38* 0.14 0.44*


Indifference 0.73** 0.57** 0.06 0.39* 0.35***
* P < 0.05; ** P < 0.01; *** P < 0.001
82 G. Buchkremer et al.
Table 4. Rank Correlation Coefficients (Spearman) Between EFA Factors and Psychopathological
Symptom Areas (AMDP) (n = 22-24)

Impairment
Attention Compul- Delusion Hallu- Ego Affective
EFA disorder sion cination disorder disorder
factors

Criticism 0.38* 0.15 0.28*** 0.06 0.35* 0.35*


Overprotec-
tiveness 0.16 0.14 0.11 0.28*** 0.06 0.Q7
Rejection 0.09 0.10 0.52** 0.13 0.Q7 0.21
Indifference 0.42* -0.13 -0.04 0.32*** 0.08 0.10
Warmth -0.33*** 0.28*** -0.Q7 -0.46* -0.09 -0.Q1
Acceptance -0.26 0.10 -0.14 -0.44* -0.16 0.02
* P < 0.05; ** P < 0.01; *** P < 0.001

Emotional Family Atmosphere and found to have prognostic value , also showed
Psychopathology of the Patient a correlation with disorders of attention.
The paranoid hallucinatory syndrome
Marked involvement of the relatives in the
was not correlated with the EFA factors of
patient'slife can be understood as a possible
criticism or indifference. However, in the
reaction of the relatives to a schizophrenic
delusions there was a significant correlation
disorder (coping strategies). The correla-
with the EFA factor of rejection. Hallucina-
tion between the EFA and the psychopa-
tions correlated with low levels of warmth
thological status of the patient will there-
and acceptance.
fore be investigated next.
The following investigation is intended to
The psychopathological status of the pa-
clarify whether there is a correlation be-
tient was scored by third-person rating
tween the cognitive disorders rated by the
using the AMDP system (a German psychi-
patients themselves and the EFA.
atric rating system; AMDP 1982) and by
The patients (n = 24) answered the short-
self-rating using the Frankfurt syptom in-
ened form of the FBF by which the subjec-
ventory (FBF; Siillwold 1977).
tive experience of thought and perception
processes can be surveyed (Siillwold, 1977,
Results of the Third-Person Rating
(AMPD)
1983). The shortened form of the FBF as-
sesses three factors.
The EFA factor of criticism displayed sig- Factor A: Disturbance of perception and
nificant correlations with three areas of psy- movement activity
chopathological disorders (attention, ego, Factor B: Disturbance of thought and
and emotional disorders). The EFA factor speech
of indifference, which (like criticism) was Factor C: Anxiety and coping reactions

Table 5. Rank Correlation Coefficients (Spearman) Between FBF Scores and EFA Factors (n = 24)

EFA
FBF FBFscore FBFfactorA FBF factor B FBFfactorC

Criticism 0.30*** 0.25 0.28*** 0.36*


Indifference 0.60** 0.56** 0.59** 0.37*
* P < 0.05; ** P < 0.01; *** P < 0.001
Emotional Atmosphere in Families of Schizophrenic Outpatients 83
Results of the Self-rating (FBF) A and B) are significantly correlated with
"indifference" of the relatives. Anxiety and
There were statistically significant correla- coping reactions of the patients (factor C),
tions between the EFA factors of criticism on the other hand, are correlated with criti-
and indifference and the FBF factors. In cism and indifference of the relatives.
particular, indifference did not only corre- The validation of the MFB with other cli-
late in the overall score of the FBF but also nical or prognostic criteria failed to yield
significantly with the individual factors any results which were significant in the sta-
below the 1% level. tistical sense. In particular, there were no
The results appear to indicate that schizo- significant correlations between the MFB
phrenia-linked disorders of cognitive and the social status and disease course of
thought and perception processes (factors the patients.

Discussion
In contrast to the CFI, the MFB proved to teria of doubling the neuroleptic medica-
be a practical instrument for rating the en- tion indicates that the more chronic patients
tire EFA in the presence of all family mem- who are undergoing chronic neuroleptic
bers and of the patient. The results indicat- treatment are likely targets of indifference.
ed a satisfactory criterion validity. The in- In patients with a mainly critical family at-
terrater reliability was sufficient. mosphere, a long period of neuroleptic
With regard to prognostic criteria, the re- treatment was rarer. In these patients, there
sults of the MFB agreed with previous CFI was a more frequent fresh prescription of
research. As noted with the CFI, relapse neuroleptics in cases of crisis. Furthermore,
was associated with criticism expressed by they also experienced a subjective feeling of
the relatives. The present study confirms relapse significantly more often.
the results of Brown et al. (1972) as well as With some caution, these results can be
Vaughn and Leff (1976 b). interpreted in the following way: A critical
Surprisingly, an indifferent attitude of the family atmosphere is too great a strain for
relatives with regard to the patient likewise many patients, above all when they are
indicated a raised risk of relapse of the pa- under chronic neuroleptic treatment so that
tient. One reason for this appears to be that their vulnerability threshold is exceeded
the MFB assesses not only the family mem- and a relapse occurs. A high measure of in-
bers who are interacting most intensively difference in the family indicates that self-
with the patient but also the remaining rel- help potentials are absent in these families
atives. Evidently, both an emotionally in- and in these patients so that pychiatric in-
tense as well as a low-tension family atmos- terventions (e.g., rehospitalizations) be-
phere can entail a raised risk of relapse. come necessary to a greater extent in times
Great significance is to be accorded to of crisis.
this finding since it indicates that the "tight- In the investigation of the connection be-
rope walk" between overstimulation and tween the symptoms of the patients and the
understimulation as described by Wing EFA, significant correlations were revealed
(1976) also applies to the EFA of schizo- with "criticism" and the psychopathological
phrenic patients. Thus, not only emotional symptom areas of attention, ego, and emo-
overinvolvement in the families of schizo- tional disorders. In addition, disorders of
phrenic patients is to be avoided, but also a attention also correlated with indifference
lack of involvement is to be prevented. This of the relatives.
means that family therapies which empha- Analogous findings resulted when the ex-
size more reserve or more indifference by tent of the disorders of cognitive processes
the relatives toward their unwell family rated by the patients themselves as well as
member must be viewed with caution. their coping reactions were related to the
The finding that an indifferent family at- EFA.
mosphere is associated with the relapse cri- These findings indicate a reciprocity of
84 G. Buchkremer et al.
the correlations between the EFA and the mission and EE status. This is probably be-
psychopathological status of the patients. cause our patients were examined 6 months
The correlation between the EFA and the after their discharge from the hospital. The-
emotional expression behavior of the pa- refore, the range of symptoms from few to
tients could already be demonstrated in an severe was broader than in the investiga-
earlier investigation of Brown et al. tions of the authors mentioned above, who
(1972), Vaughn and Leff (1976 b), and examined patients on admission, when they
Miklowitz et al. (1983), who reported no as- normally all have severe symptoms.
sociation between clinical symptoms on ad-

References
AMPD. (1982). Das AMPD-System. Manualzur suchung zum EE-Index. Aktuelles Forum Psy-
Dokumentation psychiatrischer Befunde (4th cho (Suppl. I). (pp. 9-10). Erlangen: Perimed.
ed.). Berlin Heidelberg New York: Springer. Mikiowitz, D., J., Goldstein, M. J., and Falloon,
[English translation: Guy, W., and Ban, T. A. J. R. H. (1983). Premorbid and symptomatic
(Eds.) The AMDP system, Berlin, Heidelberg, characteristics of schizophrenics from families
New York: Springer (1982)]. with high and low levels of expressed emotions.
Brown, G. W., Birley, J. L., and Wing, J. K. Journal of Abnormal Psychology, 92,
(1972). Influence offamily life on the course of 359-367.
schizophrenic disorders: A replication. British Siillwold, L. (1977). Symptome schizophrener
Journal of Psychiatry, 121,241-58. Erkrankungen. Uncharakteristische Basissto-
Buchkremer, G., and Fiedler, P. (1982). Ange- rungen. Berlin, Heidelberg, New York: Sprin-
hOrigentherapie bei schizophrenen Patienten. ger.
In Helmchen, H., Linden, M., and Ruger, U. Siillwold, L. (1983). Schizophrenie. Stuttgart:
(Eds.), Psychotherapie in der Psychiatrie. Ber- Kohlhammer.
lin, Heidelberg, New York: Springer. Vaughn, C., and Leff, J. (1976 a). The measure-
Buchkremer, G., and Lewandowski, L. (1984). ment of expressed emotion in the families of
Therapeutische Gruppenarbeit mit AngehOri- psychiatric patients. British Journal of Social
gen schizophrener Patienten. In: C. Anger- and Clinical Psychology, 15, 157-165.
meyer, and A. Rinzuen (Eds.), Die AngehOri- Vaughn, C., and Leff, J. (1976 b). The influence
gengruppe. Stuttgart: Enke. of family and social factors on the course of psy-
Buchkremer, G., Lewandowski, L., and Fiedler, chiatric illness: A comparison of schizophrenic
P. (1982). Emotionale Interaktionsmuster in and depressed neurotic patients. British Jour-
Familien schizophrener Patienten. Eine Unter- nal of Psychiatry, 129, 125 -137.
7. The Marriages and Interaction Patterns
of Depressed Patients and Their Spouses:
Comparison of High and Low EE Dyads
J. M. Hooley and K. Hahlweg

Introduction
Although we can now be relatively confi- titude expressed during an interview has a
dent that there is indeed a reliable associa- corresponding behavioral analogue in na-
tion between family levels of expressed turalistic patient-relative interactions. Only
emotion (EE) and relapse rates in schizo- in recent years has the validity of this as-
phrenic and depressed patients, a word of sumption actually been subjected to empiri-
caution is perhaps appropriate. Despite the cal scrutiny (see Chap. 4). Results of a study
encouraging results of recent intervention published in 1983 by Valone, Norton,
work, we are still some distance from a full Goldstein, and Doane first suggested that
understanding of what EE actually is and there might indeed be differences between
how it might operate to influence the pro- the interactions of families which varied ac-
cess of relapse. Discussions of the content of cording to EE level. Using a sample of 52
interviews conducted with high and low EE disturbed but non psychotic adolescents
relatives, such as the one provided by and their families, these investigators were
Vaughn in Chap. 8, are of clear value in in- able to demonstrate that in affectively
creasing our knowledge of the emotional charged situations, parents who expressed
responses of families and in enhancing our high EE attitudes made significantly more
understanding of how they cope with a psy- criticisms during face-to-face interaction
chiatrically ill individual. with their offspring than parents who were
A second approach to understanding EE low in EE.1
concerns systematic investigation of the be- Valone et al.'s results are important be-
havior of high and low EE relatives, in an cause they indicate that a high EE attitude
effort to learn more about what goes on might be associated with high levels of criti-
when family members are involved in direct cal behavior toward a patient. Additional
interactions with an ill patient. Despite the but rather weak support for behavioral dif-
importance of this avenue of research, only ferences between high and low EE relatives
in very recent years have investigators also comes from a study conducted by Kui-
turned their attention toward the study of
the behavioral correlates of high and low 1 While such data are encouraging, two minor
EE attitudes. methodological issues should be noted. First, the
Clearly though, if high EE relatives have subjects used in the study were not adult psychia-
a negative influence on the course of a pa- tric patients (the population on which all previous
tient's illness, it is likely that some differ- EE research has focused) but were disturbed and
ences between high and low EE families possibly "preschizophrenic" adolescents.
must exist to trigger the relapse process. Second, the assessment of levels of EE was made
Indeed, this is an assumption implicit in all by rating the UCLA parental interview and not
EE work. At the present time, however, we the CFI which is the standard EE assessment
instrument. How much effect the use of a dif-
have relatively little information about the ferent interview has on the ratings of EE is not
types of behavior or behavior patterns as- clear, but nevertheless this is a feature of the
sociated with high and low EE attitudes. study which should be borne in mind in any inter-
The EE literature assumes that a critical at- pretation of the data.
86 J. M. Hooley and K. Hahlweg
pers, Sturgeon, Berkowitz, and Leff that some real difficulties do exist within the
(1983), which investigated rates of talking relationships of patients and high EE family
and durations of looking in high and low EE members. The physiological data referred
relatives. Although no differences between to earlier (see Chap. 2) also lend further
patients were apparent, high EE relatives support to this view. Since there is now evi-
did spend more time talking to patients and dence that high family levels of EE are asso-
less time looking at them than their low EE ciated with elevated rates of relapse in de-
counterparts. Such findings are consistent pressed patients (see Chap. 2), it is becom-
with the view of Berkowitz, Kuipers, Eber- ing clear that EE influences are not specific
lein-Vries, and Leff (1981) that low EE rel- to schizophrenia. Information about the in-
atives are better listeners. terpersonal relationships and interaction
To date, perhaps the best study of the in- patterns of depressed individuals and their
teractional correlates of EE in the families relatives is thus important and worthy of
of schizophrenics is that of Miklowitz and discussion here because of its potential val-
his coUegues (Miklowitz, Goldstein, Fal- ue for furthering our understanding of the
loon, and Doane, 1984). In this investiga- nature of EE. Since no data currently exist
tion, not only did high EE parents differ which examine such issues in schizophrenic
from low EE parents - the former showing samples, a chapter on depressed patients
more emotional negativity toward their off- has consequently been included in this
spring during face-to-face interactions - book.
but within the high EE group differences One principal difference between schizo-
were also found between high EE critical phrenics and depressed patients, however,
and high EE overinvolved parents. Over- is that the latter are much more likely to be
involved parents were much more likely to married. Their key relative is thus most
use neutral-intrusive statements than high likely to be a spouse. This provides an ideal
EE critical parents. Thus, the pattern of in- opportunity for the assessment of the rela-
teraction exhibited in schizophrenic fami- tionship between the patient and relative
lies may differ not only according to the EE using psychometrically sound inventories of
level of the relatives, but also according to marital satisfaction and for examining the
whether there is marked evidence of emo- association between marital harmony and
tional overinvolvement. levels of EE. This chapter will focus on the
All three studies of the behavioral corre- marital satisfaction levels reported by high
lates of EE described above were con- and low EE dyads2 within a depressed sam-
ducted using schizophrenic (or "preschizo- ple. In addition, data will be presented con-
phrenic") patients and their families. The cerning the interaction styles typical of such
behavioral data from these samples, togeth- groups. Finally, some remarks relevant to
er with the interview data presented by intervention work with high EE families
Vaughn in Chap. 8, clearly suggest that all is will be made, based on the results describ-
not well within high EE families and imply ed.

Subjects
The data presented in this chapter are based videotaped subgroup and the full sample
on a total sample of 44 patients and their (see Hooley, 1984) revealed that there was
spouses, all of whom were recruited while no tendency for the 30 videotaped couples
the patients were in a hospital suffering
from an episode of major depressive dis-
2 Throughout this chapter, the term high EE cou-
order. Since not all of these couples agreed
ple or high EE dyad will be used to refer to a part-
to be videotaped, however, behavioral data nership involving a depressed patient and a high
are available on only 30 dyads. Demo- EE spouse. The term low EE couple will be used
graphic data and data concerning EE levels in a similar way to denote the relationship be-
and marital satisfaction ratings are based on tween a depressed patient and his/her low EE
the full sample. Comparisons between the spouse.
The Marriages and Interaction Patterns 87
Table 1. Demographic Characteristics of Patients and Spouses Contributing Data to the Study

Group M SD
Patients (n = 44)
Age 48.2 11.7
DAS 103.6 17.8
Beck 26.0 11.0
Social class 19.6 11.1
Children 2.3 1.1
Length of marriage (years) 21.8 13.0
Spouses (n = 44)
Age 48.8 11.9
DAS 106.0 16.6
Beck 5.6 3.9

to be in any way untypical of the total re- from three psychiatric hospitals in or near
search sample in their EE levels or their Oxford, England and, as can be seen from
level of reported marital satisfaction. Table 1, are fairly representative of a mid-
All participating patients were recruited dle-aged, middle-class population.

Inclusion Criteria
To be accepted into the study, patients were tory (BDI) scores (Beck, Ward, Mendel-
required to meet the criteria of the Present sohn, Mock, and Erbaugh, 1961) confirm
State Examination (PSE; Wing, Cooper, that the patients recruited were generally
and Sartorius, 1974) and be cases of depres- severely depressed, their mean BDI score
sion at ID level 5 or above. In addition, it being 26.0. In contrast, their spouses
was also necessary for each patient to meet showed the low BDI scores typical of non-
the Research Diagnostic Criteria (Spitzer, depressed individuals (mean BDI for
Endicott, and Robbins, 1978) for major de- spouses = 5.6).
pressive disorder. Beck Depression Inven-

Assessment of EE and Videotaping


Once it had been established that a particu- ferences technique (Strodtbeck, 1951) was
lar patient met the criteria for inclusion into used to generate items for discussion. Vid-
the study, the spouse was interviewed either eotaping was carried out in the hospital
at home or during a visit to the hospital, us- setting except in the case of one couple
ing the Camberwell Family Interview. This who, due to the patient's refusal to remain
interview, used to assess family levels of in the hospital, had to be videotaped at
EE, is fully described in Chap. 2. Then, home. During this recording, all efforts
some days after the interviews had been were made to ensure that conditions were
completed, couples who consented were kept as similar as possible to those used in
videotaped while talking together for a pe- the hospital setting.
riod of 15 min. The Strodtbeck revealed dif-

Coding the Videotaped Interaction


The behavior of each couple videotaped partnerschaftliche Interaktion (KPI). This
was coded using the Kategoriensystem fur system, developed by researchers at the
88 J. M. Hooley and K. Hahlweg
Max Planck Institute of Psychiatry in categories and classified as either positive,
Munich, is expressly designed to handle negative, or neutral. Cohen's Kappa was
marital interaction data and has been de- 0.81. Full details of the coding system, its
monstrated to have good reliability and va- psychometric properties, and its method of
lidity. Although the KPI contains 12 dif- application, can be found in Hahlweg, Reis-
ferent verbal codes, for the purposes of the ner, Kohli, Vollmer, Schindler, and
analyses to be described below, all behav- Revenstorf (1984).
iors were collapsed into their superordinate

LevelsofEE
Spouses were assigned to the high or the tape data were available actually made ex-
low EE groups by a median split of the num- actly six critical comments, the median split
ber of critical comments made. Thus, resulted in high and low EE groups near-
spouses were placed into the high EE group ly identical to those recognized by Brown,
if they made seven or more critical com- Birley, and Wing (1972) and Vaughn and
ments; those who made six comments or Leff (1976) and found to be significantly as-
less were categorized as being low in EE. sociated with relapse rates in schizophrenic
Since none of the spouses for whom video- populations.

High and Low EE Spouses


A high EE relative may be one who makes their critical comments. The third emotion-
critical comments, emotionally over- ally overinvolved spouse, however, was a
involved remarks, or both. Emotional over- man who made no critical remarks at all
involvement in spouses, however, is much while discussing with his depressed wife. His
less common than it is in parents. In the wife unfortunately proved unable to com-
present sample, this is reflected by the fact plete more than a few minutes of videotap-
that of the 44 spouses interviewed, only 3 ing, and this couple did not therefore con-
showed levels of emotional overinvolve- tribute any behavioral data to the study. All
ment high enough to classify them as high high EE spouses on whom videotaped data
EE on the basis of this index alone. More- are available and whose interactions are de-
over, two of these spouses were also highly scribed in this chapter are thus critical indi-
critical and thus would have been placed viduals.
into the high EE group solely on the basis of

Demographic and Clinical Findings


Planned t comparisons performed on the high EE spouses is not in itself very remark-
high and low EE groupings derived from able since all hostile comments are, by def-
the median split revealed several important inition, also critical. Thus, individuals mak-
differences. As Table 2 shows, high EE ing larger numbers of critical comments are
spouses were younger than low EE spouses more likely to make some comments which
(mean age for high EE group = 44.4; mean are also hostile, and this is reflected in the
age for low EE group 53.3: t = -2.56, P < strong positive correlation which exists be-
0.02) and had been married for less time tween the two variables (r = 0.53, n = 43,
(t = -2.56, P < 0.02). High EE spouses P < 0.001).
were also rated as less warm than low EE Differences between high and low EE
spouses (CFI rating of 1.8 vs 3.8: t = -4.93, spouses were also foundf when levels of
P < 0.001) and more hostile (t = 3.84, P < marital adjustment were examined. Using
0.001). The higherlevel of hostility found in scores obtained on the Dyadic Adjust-
The Marriages and Interaction Patterns 89
Table 2. Comparison of High and Low EE Spouses

HighEE LowEE
Measure (n = 24) (n = 18) P
Age M 44.4 53.3 <0.02
SD 9.5 12.8
Length of marriage M 17.7 25.6 <0.05
SD 10.4 14.6
Children M 2.3 2.4 NS
SD 0.9 1.5
Social class M 17.9 21.7 NS
SD 11.2 11.1
BDIofspouse M 5.7 5.1 NS
SD 4.4 3.1
BDlofpatient M 25.9 26.2 NS
SD 11.1 11.3
Warmth" M 1.9 3.9 <0.001
SD 1.4 1.1
Hostility" M 1.6 0.4 <0.001
SD 1.1 0.9
Positive remarks" M 1.7 2.6 NS
SD 2.3 1.7
D AS of spouse M 99.2 112.4 <0.02
SD 16.0 13.7
DAS of patient M 97.4 111.6 <0.05
SD 12.5 20.7
"CFI rating.

ment Scale (DAS), a self-report inventory spouses also did not differ according to EE
of marital satisfaction developed by Spanier level. Thus, high EE spouses do not appear
in 1976, high EE spouses reported being to be critical simply because they have more
less satisfied with their marriages than low severely depressed partners or because they
EE spouses. This is reflected by their lower themselves feel more depressed than low
DAS scores (99.2 vs 112.4, t = -2.52, P < EE spouses, nor does having a highly criti-
0.02). cal spouse seem to influence the level of de-
Some variables, on the other hand, did pressed mood reported by the patient. The
not discriminate between spouses differing correlation between the BDI score of the
in EE levels. These variables included so- patient and the number of critical remarks
cial class, number of children, and also the made by the relative was 0.14 (NS). The
BDI scores of both patients and spouses. correlation between the BDI score of the
The findings for BDI scores are interesting spouse and the number of critical comments
since they suggest that the intensity of the he or she makes is even lower (r = -0.05,
depression reported by the patient is not it- NS). The amount of criticism made by the
self directly related to the number of criti- spouse thus seems to be independent of
cisms made by the spouse. Moreover, the both the BDI score of that spouse and ofthe
level of the depressed mood reported by BDI score of their patient-partner.

Marital Satisfaction Levels


In contrast to the results for BDI scores de- also a variable related to the frequency of
scribed above, the quality of the marital re- critical remarks received. Just as high EE
lationship does seem to be an important spouses reported higher levels of marital
variable and one which is associated with distress than low EE spouses, patients liv-
the frequency of critical remarks made. It is ing with high EE partners also reported
90 J. M. Hooley and K. Hahlweg
being more unhappily married than pa- tween high and low EE spouses investigated
tients living with low EE partners (DAS a second time. The repeated analyses re-
scores: 97.4 vs 111.6, t = 2.35, P < 0.05). vealed that the only variable which did not
The number of critical comments made (in discriminate as before was duration of mar-
the cases of spouses) or received (in the case riage - a finding which is hardly suprising
of patients) was significantly associated given the close association between this and
with the reported DAS score - high levels age. All other variables, however, still
of criticism being related to low levels of showed differences between the high and
marital satisfaction. In patients, there was a the low EE spouses. Thus, when the age dif-
correlation of -0.47 between criticism re- ference between the groups is reduced to
ceived from the spouse and DAS score nonsignificant levels by the systematic
(n = 34, P = 0.005) while in spouses the removal of selected individuals from those
correlation between DAS score and criti- groups, high EE spouses were still rated as
cism given was -0.32 (n = 34, P < 0.05, being less warm and more hostile and still
onetailed). reported higher levels of marital distress
Although several differences exist be- than low EE spouses.
tween high and low EE spouses, the fact Such conclusions are further supported
that there is a significant age difference be- by the fact that the number of critical com-
tween two groups presents a problem. Do ments made by the spouse was not signifi-
the differences described truly reflect genu- cantly correlated with age (r = -0.24, n =
ine differences between high and low EE 43, P> 0.1) and by comparisons made us-
spouses or are such differences simply arti- ing data from the 30 spouses for whom vid-
facts which have arisen as a consequence of eotape data were available (see Hooley,
the age difference between the groups? To 1984). Within this subsample, the high and
answer this question, it is necessary to per- low EE spouses did not differ significantly
form the same statistical analyses on high in age, nor did they differ in the number of
and low EE groups which do not differ in years they had been married. However, as
age. To do this, the youngest ofthe high EE found in the larger sample, differences did
spouses and the oldest of the low EE exist between high and low EE spouses for
spouses were systematically removed from warmth, hostility, and marital satisfaction.
the groups in a pairwise fashion until a t test In view of this, it seems reasonable to sug-
revealed that no significant age difference gest that such variables do reflect genuine
between the two EE groups remained. Da- differences between high and low EE
ta from these age-equivalent groups were spouses and cannot be explained simply by
then reanalyzed and the differences be- reference to age.

Interaction Patterns of High and Low EE Dyads


In addition to the marital and demographic criticisms, disagreements, and justifica-
data described above, data concerning the tions.
interaction patterns of 30 couples were also To facilitate comparison between the
obtained by means of videotaped observa- high and low EE dyads, cumulative records
tions. These took place while the couple of each of the 30 interactions were pro-
was left alone to discuss issues on which duced using a pen plotter. Figure 1 provides
they held differing opinions. All interac- an example of the type of plot produced by
tions lasted 15 min. The behavior of the this method. In this plot, which shows data
couple was subsequently coded into posi- from a low EE couple, the patient's behav-
tive, negative, or neutral categories. Inter- ior is represented by the solid black line,
actions of high and low EE dyads were then while data from the spouse are shown by the
compared. Examples of verbal behavior broken line.
rated as positive are agreements, self-dis- A positive behavior causes the pen plot-
closures, and accepting statements, while ter to move upward while a negative behav-
negative behavior is comprised primarily of ior results in the pen moving down. Any
The Marriages and Interaction Patterns 91
LEE MAR2
10

60

50

40

30

20

10

-10 Patient

- 20 Spouse

- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 1. Low EE dyad: Positive interaction pattern.

HEE ST01
10

60

50

40

30

20

10

-10 Patient

- 20 Spouse

- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140

Fig. 2. High EE dyad: Negative interaction pattern.


92 J. M. Hooley and K. Hahlweg
HEE : JOB2
10

60

50

40

30

20

10

-10 ---Patient

- 20 ---Spouse

- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 3. High EE dayd: Asymmetric interaction pattern.

HEE GRA2
10

60

50

40

30

20

10

-10 Patient

- 20 Spouse

30 Change
- ~---.--.---.---.---.---.---r---r-~~~---.---.--~~~
o 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 4. High EE dyad: Neutral interaction pattern.
The Marriages and Interaction Patterns 93
Table 3. Relationship Between EE and Interaction Pattern
Interaction pattern
Neutral, negative,
EE Positive or asymmetric Total
Low 9(30.0%) 3(10.0%) 12
High 5(16.7%) 13(43.3%) 18
Total: 14 16 30
x = 6.5 (P < 0.01)
Percentage agreement = 73.3%

neutral behavior is denoted by a line paral- EE levels of the spouses), by focusing on


lel with the central base line (broken), their overall style, with couples who showed
which is the neutral position, falling as it a clear and sustained positive pattern being
does between the positive and negative separated from those who exhibited a neu-
sides of the ordinate. The total number of tral, negative, or asymmetric pattern, 73.3 %
utterances is shown on the abscissa, while of dyads were found to be correctly identi-
the ordinate represents the extent of the de- fied as high or low in EE. As can be seen
viation from the neutral position. Thus, the from Table 3, the pattern most typical of
couple in this figure shows a strongly posi- low EE dyads is one of continuous positive
tive interaction pattern. The plot indicates exchange. This is shown in 9 of the 12 low
that both patient and spouse begin positive- EE couples. By contrast, such a positive
ly and generally remain positive throughout pattern is only found in 5 of the 18 high EE
the interaction. By contrast, the couple dyads (Chi-square = 6.5, P < 0.01). Within
plotted in Figure 2 shows a very different in- such dyads, interaction patterns tend to be
teraction style. In this dyad, positive behav- negative, neutral, or asymmetric, with hus-
ior is much less consistent and, as time pro- band and wife showing independent behav-
gresses, the pattern of the interaction grad- ior profiles.
ually becomes more negative. t Tests also reveal the positive interaction
The latter type of interaction pattern is pattern to be associated with lower levels of
typical of high EE dyads in this study. Whe- criticism. While spouses whose dyadic in-
reas low EE dyads generally show a clear- teraction pattern is nonpositive (i.e., nega-
cut positive pattern, high EE couples have tive, neutral, or asymmetric) make a mean
more varied, but nevertheless nonpositive, number of 10.8 critical comments about
styles of interaction. Thus, the couple their partners during an interview, those
whose data are shown in Figure 3 have an whose dyadic interaction plots reveal a po-
asymmetric pattern, while those shown in sitive pattern make only 5.7 critical remarks
Figure 4 are generally neutral in their (t = 2.6, P < 0.02). The cumulative inter-
behavior. action plots also validate the Dyadic Adjust-
The interaction patterns of high and low ment Scale, with positive patterns being-
EE dyads are so different that it is actually more indicative of marital satisfaction and
possible to identify couples reliably as high nonpositive patterns being more typical of
or low in EE on the basis of their interaction marital distress (DAS scores: 113.5 vs 96.9,
styles. When couples were grouped visually t = 3.2, P < 0.005).
by the second author (who was blind to the
94 J. M. Hooley and K. Hahlweg
Discussion
The data presented in this chapter suggest EE interactions and, focusing as they do on
that EE is a measure of important aspects of global measures of positive, negative, and
the interpersonal relationships of depressed neutral behavior, fail to capture the real es-
patients and their spouses. While it is not sence of such relationships. In subsequent
yet clear how relevant these findings are publications, we will present more detailed
for schizophrenic patients, both partners data concerning the specific behaviors
within high EE depressed relationships re- which both differentiate high and low EE
port being less happy with their marriages individuals and discriminate between de-
than individuals involved in low EE rela- pressed patients interacting with them. The
tionships. Moreover, for both patients and very important issue of the sequencing of
spouses, high EE levels are correlated with these behaviors will also be addressed with
low levels of marital satisfaction, although reference to positive and negative escala-
for patients the magnitude of the correla- tion patterns.
tion is much larger. Those patients who live Returning to the data presented here,
with the most critical spouses are the most however, the crucial question is why high
unhappy with their marriages. EE dyads interact more negatively (and less
Behavioral observations of the interac- positively) than low EE dyads. Any inter-
tions which take place within high and low ventions made within high EE families
EE dyads also confirm these self-report da- must necessarily be predicated on assump-
ta. Whereas the behavioral-interaction pro- tions about the answer to this question.
files of low EE dyads typically reflect a con- While a high EE attitude may be reflective
tinuous exchange of positive verbal com- of underlying personality variables in some
munication, those generated by high EE individuals, in others it may arise as a con-
couples are much more variable. They are sequence of continued exposure to particu-
also much less likely to be positive. Inter- lar types of behavior in patients. In still
action patterns of high EE dyads typically other instances, high EE may be the pro-
involve neutral, negative, or asymmetric duct of the interaction of both these factors,
exchanges. with certain types of symptoms (or constel-
Rather importantly, cumulative plots lations of symptoms) eliciting a high EE re-
which record the positive, negative, and sponse in certain types of individuals.
neutral aspects of interactions appear to be While the results of this investigation
a reliable way of differentiating high from highlight the absence of mutual exchanges
low EE dyads. Such a discrimination can be of positive communication within high EE
easily made visually and, suprisingly, is best couples, they also demonstrate the diversity
made by focusing on the presence or ab- of interactional styles within this group as a
sence of positive behavior patterns. This is a whole. Most low EE dyads show quite con-
particularly interesting finding since, on the sistent patterns of positive behavior over
basis of previous studies of EE, it might the course of a face-to-face interaction. In
have been predicted that a clear-cut nega- contrast, the interaction styles of high EE
tive interaction style would have been the dyads reveal much more variability and are
most likely differentiating high and low EE sometimes negative, sometimes neutral,
dyads. Thus, while the data concerning and occasionally asymmetric or positive.
marital satisfaction levels validate the CFI Whether this diversity is a reflection of un-
and support the view that high EE relation- derlaying differences in the etiology of the
ships are generally more troubled than low high EE response is not yet clear. If this is
EE relationships, the interaction plots sug- the case, however, interaction plots such as
gest that one manifestation of these inter- these may provide valuable information to
personal problems involves the lack of po- researchers and clinicians concerning the
sitive communicatory behavior. level and type of intervention most appro-
Clearly, however, the interaction pat- priate for any particular dyad. Although we
terns described represent a relatively crude are still some distance from being able to
way of depicting the nature of high and low tailor our interventions to individual fami-
The Marriages and Interaction Patterns 95
lies, detailed data concerning families who sen ted in this chapter cannot provide us
fail to respond to conventional forms of EE with any simple answers about the optimum
modification as well as on those who do de- method of intervention for high EE fami-
rive therapeutic benefit is clearly a neces- lies, they do provide us with a basis for ask-
sary first step. EE is a subtle and complex ing more refined and informed questions
phenomenon most likely to be determined about the directions subsequent interven-
in a variety of ways. While the data pre- tion research might take.

References
Beck, A. T., Ward, C. H., Mendelsohn, M., H., and Doane, J. A. (1984). Interactional cor-
Mock, J., and Erbaugh, J. (1961). An invento- relates of expressed emotion in the families of
ry for measuring depression. Archives of Gen- schizophrenics. British Journal of Psychiatry,
eral Psychiatry, 4, 561-571. 144,482-487.
Berkowitz, R., Kuipers, L., Eberlein-Vries, R., Spanier, G. B. (1976). Measuring dyadic adjust-
and Leff, J. (1981). Lowering expressed emo- ment: New scales for assessing the quality of
tion in relatives of schizophrenics. In M. J. marriage and similar dyads. Journal of Mar-
Goldstein (Ed.), New developments in inter- riage and the Family 38,15-28.
ventions with families of schizophrenics. Lon- Spitzer, R. L., Endicott, J., and Robbins, E.
don: Jossey-Bass. (1978). Research Diagnostic Criteria for a se-
Brown, G. W., Birley, J. L. T., and Wing, J. K. lected group of functional disorders. New
(1972). Influence of family life on the course of York: Biometric Research Unit, New York
schizophrenic disorders: A replication. British State Psychiatric Institute.
Journal of Psychiatry, 121,241-258. Strodtbeck, F. L. (1951). Husband wife interac-
Hahlweg, K., Reisner, L., Kohli, G., Vollmer, tion over revealed differences. American
M., Schindler, L., and Revenstorf, D. (1984). Sociological Review, 16,468-473.
Development and validity of a new system to Valone, K., Norton, J. P., Goldstein, M. J., and
analyse interpersonal communication (KPI: Doane, J. A. (1983). Parental expressed emo-
Kategoriensystem fUr partnerschaftliche Inter- tion and affective style in an adolescent sample
aktion). In K. Hahlweg and N. S. Jacobson at risk for schizophrenia spectrum disorders.
(Eds.), Marital interaction: Analysis and mo- Journal of Abnormal Psychology, 92 (4),
dification. New York: Guilford. 399-407.
Hooley, J. M. (1984). Criticism and depression. Vaughn, C. E., and Leff, J. P. (1976). The in-
Unpublished D. Phil. thesis, University of Ox- fluence of family and social factors on the
ford. course of psychiatric illness. British Journal of
Kuipers, L., Sturgeon, D., Berkowitz, R., and Psychiatry, 129, 125 -137.
Leff, J. (1983). Characteristics of expressed Wing, J. K., Cooper, J. E., and Sartorius, N.
emotion: Its relationship to speech and looking (1974). The description of psychiatric symp-
in schizophrenic patients and their relatives. toms: An introduction manual for the PSE and
British Journal of Clinical Psychology, 22 (4), cat ego system. London: Cambridge University
257-264. Press.
Miklowitz, D. J., Goldstein, M. J., Falloon, I. R.
8. Patterns of Emotional Response
in the Families of Schizophrenic Patients
C. E. Vaughn

Introduction
In Chap. 2, Hooley succinctly summarizes medication) and others did not. The origins
the history of expressed emotion (EE) re- of schizophrenia were assumed to be bio-
search and its principal findings to date. She logical; there was considerable scepticism
reviews the considerable body of evidence regarding some theorists' views of the fami-
which suggests that the EE index has pre- ly's role in the etiology of the illness. Never-
dictive validity where relapse patterns in theless, a series of anomalous findings early
schizophrenia are concerned and refers to on in the research suggested that influences
the content and concurrent validity studies from within the home might affect the
which offer further proof that EE is concep- course of a schizophrenic illness. One such
tually sound. However, she also acknowl- anomaly was the link between relapse and
edge the existence of unresolved questions type of living group; another was the fact
and issues raised by the EE investigations. that male patients apparently did well even
The intention of this chapter is to take up if unemployed as long as the mother went
some of these questions and issues and ex- out to work (Brown, Carstairs, and Top-
plore them in the light of unpublished data ping, 1958; Brown, 1959). Both anomalies
from relatives' interviews - rich sources of could be explained, the investigators rea-
information concerning patterns of emo- soned, if patients were reacting to close ties
tional response and family interaction in the because of a sensitivity related to the dis-
months preceding a psychiatric admission. ease process. Theories of sensory overload
The material to be presented suggests some and emotional overarousal in schizophrenia
directions for further research and tentative perhaps were relevant. It therefore seemed
guidelines for clinical interventions in the appropriate to try to identify aspects of fam-
future. ily life which might contribute to a better or
A recurrent criticism of the EE research worse psychiatric outcome. There was no
is that it has failed to indicate precisely what suggestion that the qualities or characteris-
the concept measures, how it manifests it- tics to be identified were necessarily deviant
self, or how it operates to influence the vul- or that they were unique to the relatives of
nerable individual. While it appears to tap schizophrenic patients. This important
qualities of family life which can either pro- point is emphasized by Brown (1985) in a
tect patients against relapse or make relapse recent account of the path to the "discov-
more likely by the exacerbations of symp- ery" of EE. He recalls:
toms, the process by which this happens has
remained unclear. It seemed important that the occasional presence
Hints as to what might be going on ap- of deeply disturbed or unusual relationships be-
tween parent and patient should not be allowed
peared in the early epidemiological studies
to dominate our thinking. If I had any hunch
of schizophrenia conducted by Brown and about what was going on, it was that it involved
his group. This work began as a search for something a good deal less fundamental, indeed
environmental explanations of why some everyday. Therefore one way forward would be
patients relapsed after discharge (despite to develop an instrument capable of recording
the protection afforded by antipsychotic the range of feelings and emotions to be found in
98 C. E. Vaughn
ordinary families. Indeed, the family instrument behavior occurred and how they coped at
used to record "expressed emotion" was not de- the time. During the course of the interview
veloped with the families of schizophrenic pa- the focus shifts from symptom behaviors to
tients and it did not occur to me that there was more general patterns of family interaction,
anything amiss in this. such as the occurrence of irritability and
Brown and his colleagues' initial attempts quarreling and the amount and intensity of
to identify features in the home environ- contact between the patient and other fam-
ment predictive of relapse produced hun- ily members. There are specific questions
dreds of rating scales concerning different too about the quality of the relationship be-
aspects of family life. Of all these scales, tween patient and relative: Can you get
only three showed independent relation- close to him? Have your feelings for him
ships with the course of schizophrenia: changed since the trouble came on? Addi-
relative's critical comments, hostility, and tional questions concern the impact of the
emotional overinvolvement. These three illness: What difference has this hospitaliza-
scales together comprise the index of EE, tion made to you and the family? What has
which essentially is an indicator of a rela- been the most disturbing aspect of the trou-
tive's negative affect or intrusive overcon- ble for you? Although the interviewing pro-
cern toward the patient. Two additional EE cedure is governed by rigorous guidelines,
scales, warmth and positive remarks, are the approach is a flexible one and the tone
measures of positive affect which undoubt- that of an informal conversation rather than
edly contribute to the emotional atmos- an interrogation. The result almost always
phere in the home. They were not included is a rich picture of family life during the pre-
in the EE index, however, because oftheir admission period. The quality of informa-
complex interrelationships with the other tion obtained in most instances provides
EE scales and with relapse. For example, quite a good idea of relatives' characteristic
high warmth toward the patient is associa- responses in a time of crisis and their re-
ted with a good outcome only when the rel- ported impact on the patient, as well as
atives score low on emotional overinvolve- more general patterns of family interaction.
ment (EOI). Where high warmth is found While EE researchers generally have ac-
in combination with high EOI, relapse is cepted relatives' accounts as valid, until re-
very likely. cently the assumption of veracity was based
The EE index is rated on the basis of both primarily on the usefulness of the EE index
feelings expressed during the inverview and as a predictor of symptomatic relapse. An
reported behavior outside it. The Camber- element of doubt lingered: in the absence of
well Family Interview (CFI) was designed more direct evidence, one could not be sure
to elicit two kinds of information: objective that a relative's interview behavior or re-
information concerning life in the house- ported reactions necessarily reflected what
hold in the months leading up to the pa- went on in the patient's presence. How-
tient's admission and subjective information ever, recent independent investigations of
concerning the relative's attitudes and feel- direct interactions between patient and rel-
ings toward the patient and the illness. ative have confirmed the impressions glean-
Brown believed that if the relative were ed from relatives' interviews, suggesting
asked in a neutral fashion about quite spe- that in a majority of cases there is a corres-
cific details of the illness and related events, pondence between these different sources
information about feelings would naturally of information (Miklowitz, Goldstein, Fal-
follow. A number of different interviewing loon, and Doane, 1984). Reassured by this
techniques help to ensure that this happens. knowledge, let us now consider some of the
Questions about the occurrence of patient ways in which low EE and high EE house-
behaviors cover many different aspects of a holds differ. The discussion of qualitative
particular behavior: onset, severity, fre- data which follows is based on interviews
quency, social contact, reactions of every- with several hundred relatives of patients in
one who witnessed the behavior. Relatives England, America, and Australia.
are asked to give examples of the last time a
Patterns of Emotional Response 99
EE as an Indicator of the Pre-illness Relationship
A detailed analysis of the interview data for when stressed, however, frequently found
78 relatives in the 1976 Vaughn and Leff the strain of coping with someone who was
study established a link between the con- psychiatrically ill intolerable. Feelings of
tent of relatives' criticism and the quality frustration and helplessness commonly re-
of the pre-illness relationship, for both schi- sulted in expressions of anger toward the
zophrenic and depressed samples of pa- patient. However, these relatives' criti-
tients (Leff and Vaughn, 1985). For this cisms invariably were directed at specific
analysis, a distinction was made between symptom behaviors for which the patient
critical remarks concerning symptom was not held responsible.
behaviors which first appeared in the con- Where there appeared to be a poor rela-
text of an illness episode (for example, de- tionship between patient and relative prior
lusional behaviors, changes in levels of ac- to the onset of the illness episode, critical
tivity or irritability) and critical remarks remarks were almost exclusively about
about more general, enduring personality long-standing behaviors. For both the schiz-
traits of the patient. Results revealed that ophrenic and depressed groups, approxi-
for both diagnostic groups a major deter- mately 70% of all critical remarks fell into
minant of a relative's current response to this category. Criticism tended to center on
the patient and the illness was the way in aspects of the relationship with which the
which patient and relative got along before relative was markedly dissatisfied, partic-
the present illness episode. ularly communication and the amount of af-
If the pre-illness relationship was good, fection and interest shown by the patient.
the relative at interview tended to either The relatives concerned did not identify
make no critical remarks or to confine criti- these behaviors as manifestations of illness,
cism to comments about florid symptom but considered them to be integral charac-
behaviors. A critical response seemed to teristics of the patient's personality.
depend less on the degree of the patient's Thus, it seems that the kind of remarks
disturbance than on the relative's own per- made by a relative at a crisis point (time of
sonality. Relatives who described them- admission) can provide important clues as
selves as generally tolerant and easygoing to how patient and relative get along in nor-
persons tended to be noncritical. Those mal circumstances.
who admitted to being tense or moody

Distinguishing Characteristics of High EE and Low EE Relatives


Measures of severity of psychopathology at Throughout the several decades of EE
admission consistently fail to distinguish be- research, investigators have been impres-
tween patients from low EE and high EE sed by the ways in which differences in lev-
families: high EE patients are not more ill els of EE tend to reflect differences in
than their low EE counterparts, by any cri- thresholds of tolerance, attitudes toward
terion adopted (Brown, Birley, and Wing, the legitimacy of the illness, and styles of
1972; Vaughn and Leff, 1976; Vaughn, Sny- coping. It has been possible to identify a
der, Jones, Freeman, and Falloon, 1984). number of characteristics which tend to
Miklowitz, Goldstein, and Falloon, (1983) distinguish relatives who score highly on
demonstrated that low EE and high EE criticism or emotional overinvolvement
schizophrenic patients were indistinguisha- from those who do not, as judged by their
ble on measures of premorbid adjustment behavior in the interview and reported re-
and residual symptomatology after dis- actions.
charge. The differences lie not in the pa- The first characteristic concerns the rela-
tients, but in the relatives - low EE and tive's respect for the patient's relationship
high EE relatives differ markedly in their needs, which may vary from patient to pa-
response to a patient's objective condition. tient, and by diagnosis. For example, many
100 C. E. Vaughn
schizophrenic patients find mhmate rela- doesn't shave, doesn't wash his hair, never
tionships difficult and prefer to maintain a changes his underwear - it's quite revolt-
certain social distance even when well. By ing!" This reply goes beyond mere descrip-
contrast, depressed patients may be socially tion; the strength ofthe negative reaction is
demanding and seek repeated expression of considerable.
caring and concern from persons around In another household, both parents de-
them. Low EE relatives "attend" to the pa- clared the son's playing of loud rock music
tient more; they are sensitive to requests to be a source of family tension. As with the
for either privacy and autonomy (schizo- preceding example, however, parental
phrenia) or increased social support (de- reactions differed in content and in tone.
pression). The father reported low-keyed attempts to
Additional characteristics which tend to intervene: "If he played loud music, I might
distinguish low EE and high EE relatives just say 'Tum the music down, Kev, the
are the relative's attitude toward the legiti- whole street doesn't need to hear. '" The
macy of the illness and the relative's level of mother's response was one of anger and
expectations for patient functioning. These acute distress: "Music, when he's on the
two characteristics are linked in predictable downgrade, would nearly drive you crazy.
ways. The low EE view that the illness is He'd play the same records over and over
genuine tends to result in lowered expecta- and over again, until you felt if I hear that
tions: the patient is unwell; therefore, one one more time I'll scream!"
must make allowances. Low EE relatives Low EE relatives frequently do express
consistently show greater empathy and dissatisfaction with a patient's behavior,
make more efforts to understand the pa- but the dissatisfaction is muted; it tends to
tient's ordeal than do high EE relatives. take the form of statements such as "I wish
While they are objective enough to recog- he weren't like that." Their opinions lack
nize that certain symptom behaviors are the emotional intensity of remarks made by
signs of illness, they can accept that certain high EE relatives. The use of words like
peculiar ideas or experiences might be real "revolting" and "drive you crazy" reflect
enough for the patient, and this realization strong disapproval. Indeed, the high EE
also contributes to an attitude of tolerance. relative often responds as if the behavior in
These attitudinal differences, it should be question were a personal affront. Given
noted, tend to evolve in the absence of any such strong reactions, confrontations with
professional counseling. the patient are very likely.
Finally, low EE and high EE relatives dif- Clinical intervention programs suggest
fer in their emotional reactions to the ill- that many high EE relatives have low prob-
ness. This may seem a tautological state- lem-solving skills, a conclusion supported
ment, but it is one which warrants further by relatives' own accounts. High EE rela-
examination. If one compares the respec- tives will freely acknowledge their inability
tive accounts of parents who are discrepant to react calmly and nonintrusively. Even
for EE - one highly critical, one not - the when attempts to change the patient's un-
same behavior will be described in very dif- desirable behaviors repeatedly fail, the rel-
ferent ways. The less critical relative will ative will persevere with the same ap-
tend to give a dispassionate, objective de- proaches. Predictably, a failure to adapt to
scription of a particular behavior by the pa- the changing circumstances created by the
tient, even when that behavior is undesira- illness tends to exacerbate the situation and
ble. For example, when asked about his to increase levels of tension, frustration,
son's personal hygiene (Does he look after and irritability generally.
himself all right?), one father simply an- One high EE father vividly described his
swered: "Not good. He doesn't want to inability to cope with his daughter's "mad"
shave, wash, that sort of thing." The lan- talk when ill. His response was one of ex-
guage used by the patient's mother in re- treme intolerance. In this particular case,
sponse to the same question was much less the relative recognized that the illness was
neutral: "That's a very sore point with me genuine and acknowledged the need to
... He goes beyond being a bit grubby. He show more understanding, yet no amount
Patterns of Emotional Response 101
of insight facilitated the process of adjust- kill him. The father managed to disarm his
ment: son of a knife through gentle persuasion:
I had no technique for dealing with her. I was at "Have a cup of tea, son, and let's talk about
a loss. My wife is much better talking to her when this." He did not contact the hospital until
she's like this, but I find it very difficult ... When the following morning. Admission did
she gets a bit more and more insane, I could never prove to be necessary, but a major social
- having been brought up as an engineer, used to
crisis was averted. When asked how he
examining things according to the rules of science
- I could never, ever think it worthwhile trying to managed to remain so composed, the father
talk to my daughter. It was such absolute non- replied: "It didn' worry me, I thought if he
sense! I couldn't stand it, couldn't adapt, couldn't goes for me I'll put him in his place. I wasn't
develop a method for dealing with her. But my too upset, as the wife had a breakdown
wife did. once. I do take things as they come, I sup-
Low EE relatives are more adaptable. Over pose."
time and usually by a process of trial and er- Contrary to some interpretations of the
ror - if it works, keep it up; if it doesn't, try EE data, low EE relatives do attempt to
something else - they gradually develop exercise social control over the patient, but
techniques for dealing with difficult behav- in less intrusive and confrontational ways
iors which minimize their impact. The pro- than their high EE counterparts. They also
cess by which repertoires of successful cop- exert considerable self-control. While some
ing techniques are built up is worthy of low EE relatives describe themselves as
more systematic investigation. What exists naturally easygoing, as in the above exam-
at the moment is a wealth of anecdotal ma- ple, a calm response in a crisis does not ne-
terial pertaining to relatives' efforts to come cessarily indicate a lack of emotion. Feel-
to terms with the disturbing changes ings of distress and dissatisfaction can be
brought by the illness, some of which may considerable. Frequently, there is evidence
be permanent. that low EE relatives have learned to con-
Particularly noteworthy are the excep- trol their emotions over many years, deal-
tionally calm and self-contained reactions ing not only with periodic crises but also
by some low EE relatives to extremely agi- with the everyday problems of living with a
tated or bizarre patient behaviors. Only very person who is vulnerable to episodes of psy-
occasionally does this response style seem chiatric illness. One mother described her
inappropriate, overcontrolled, or evidence trial-and-error efforts to discover what wor-
of some denial process at work. In most ked best:
cases, these relatives do seem concerned, I realized that if I got upset, exploded, it was bad
but they are not unduly anxious. Many dis- for Martin. It had a more calming effect on him if
play an admirable ability to defuse a crisis. I kept very calm. So I let many things pass. I
In such circumstances, they are likely to wouldn't make an issue. I became more permis-
have a calming effect not only on the patient sive in order to survive. You just do the best you
(an impression supported by the biological can each day. My husband and I are pretty happy-
data reviewed by Hooley) but also on other go-lucks. We don't let many things bother us, we
family members. At interview they offer try to keep a sense of humor. That's essential! In
cool, even humorous accounts of their ef- any event, we're not the same people we were
forts to deal with the patient. One low EE when we started out.
father recounted a preadmission incident in It is this quality ofJlexibility which, perhaps
which his son woke him up one night with more than any other characteristic, distin-
an announcement of a God-sent mission to guishes low EE from high EE relatives.

Impact of Different Response Styles on the Schizophrenic Patient


Relatives' accounts indicate that schizo- seldom avoided relatives who were low-
phrenic patients react to their widely vary- keyed and nonintrusive. They tended to
ing behaviors in very different ways. In the stay in the same room even if disinclined to
British and California EE studies, patients converse; they showed no inclination to re-
102 C. E. Vaughn
treat. In high EE households, however, then it's over with. But I think that's what my son
social withdrawal was commonplace. Often doesn't like. He doesn't like to hear the scream-
there seemed to be a clear link between a ing and the hollering. He doesn't like being con-
stressful stimulus and protective with- fronted, he doesn't like people to become upset
with him. It does not good at all to nag, it just
drawal by the patient. For example, one makes him more irritable.
young man divided his time between the
households of his divorced parents. In the These very similar comments, made by dif-
months after going to live in his mother's ferent relatives, were echoed again and
conflict-ridden high EE household, he again in interviews.
spent more and more time by himself, with- Thus, relatives' reported observation
drawing to his room or going for long solita- support psychophysiological findings (cf.
ry walks. During family rows, he ceased to Chap. 2) which suggest that high EE rela-
speak at all; he would cower in a corner of tives are more emotionally arousing to the
the room and put his hands over his ears as patient. Why should this be so? Research
if to shut out the noise. His mother com- into the precise mechanisms by which EE
plained that her attempts to "reach" him operates to influence the return of schizo-
seemed to make him more ill. Indeed, the phrenic symptoms is just beginning, but the
patient relapsed 3 times during a 12-month interview data provide some clues. Let us
period. It is notable that he showed no signs assume that persons prone to episodes of
of withdrawal, nor did he relapse, during schizophrenia have an underlying psycho-
the periods when he lived with his father in biological vulnerability which makes it dif-
less tense circumstances. ficult for them to process complex stimuli
A second kind of reaction by the patient and handle social relationships. Let us ac-
to overstimulation or stress was agitated ag- cept, also, that issues of control and influ-
gression. There were repeated instances in ence frequently preoccupy such persons. It
which a critical or intrusive action by the follows that certain environments may pro-
relative would provoke an irritable or vio- duce high and sustained levels of arousal in
lent outburst from the patient: schizophrenic patients which make them
Would he ever get excited or agitated? more likely to become ill again. By the rela-
That would be if someone was too much pressing tives' own accounts, these enVIronments
him. are characterized by discord and/or intru-
He likes the quiet, to be talked to softly; he sive attempts on the part of the relative to
doesn't like it when you try to press him. It makes advise, complain, or merely get through to
him very nervous.
Would he ever get irritable? Only if you aggra-
the patient. Whether or not these overtures
vated him. That would make him very angry, are well-intentioned, they are likely to be
very upset. He wouldn't say anything, but he'd viewed as threatening by persons vulnera-
get very aggressive ... He would kick chairs or ble to episodes of schizophrenia and may
throw something, to take his frustration out. precipitate a return or exacerbation of flor-
I scream and holler and get it out of my system, id symptoms.

Premorbid Personality, Relative's EE, and Relapse:


The Issue of Vulnerability
The content analysis of critical comments relapse is not due to another intervening
made in the 1976 study revealed an associa- variable thought to be associated with a
tion between the patient's previous person- poor prognosis, for example, a poor prem-
ality and the relative's emotional response, orbid personality?
suggesting that in at least a proportion of Results of the EE studies to date clarify
cases the relative was responding to ab- the ways in which different variables may
normality in the patient. In such cases, the interact to influence the outcome of any
relative's reaction may be entirely under- given patient. The schizophrenia literature
standable. how can one be sure that the link suggests that clinical variables and aspects
between a relative's EE and symptomatic of a patient's psychiatric history are not lin-
Patterns of Emotional Response 103
ked in any obvious way to the course of an month follow-up period. Those who re-
individual patient's illness. The EE findings turned to high EE relatives usually re-
suggest why this is so for patients living with lapsed. The particular vulnerability of un-
relatives. Patients showing few of the clini- married schizophrenic men again was high-
cal signs associated with a poor prognosis lighted by the analysis of differential pat-
are likely to remain well whether or not terns of parental response. Although schi-
they return to a high EE or low EE home. zophrenic sons and daughters were equally
This finding is consistent with results of likely to be found in high EE homes, the
other studies in which certain criteria such sons were significantly more likely than the
as acuteness of onset or marital status are daughters to return to homes featuring pa-
associated with a good prognosis or remis- rental conflict, according to the same three
sion in schizophrenia. Where the clinical in- studies (Brown et aI., 1972; Vaughn and
dicators are unfavorable, however, the Leff, 1976; Vaughn et aI., 1984). At the
quality of the postdischarge environment is same time, schizophrenic sons were less
highly important for the patient's clinical likely than schizophrenic daughters to be
outcome. Thus, an emotionally more neu- protected by the combined effects of main-
tral setting, such as a low EE home, exerts tenance phenothiazine therapy and reduced
the greatest protective influence on those contact with relatives, both of which can
patients who are constitutionally the most modify the effects of an excessively stimul-
vulnerable. In three different studies of ating environment. These findings explain
schizophrenia, patients with poor prem- at least in part their greater chances of de-
orbid personalities who returned to low EE veloping a chronic or relapsing condition
relatives almost always stayed well over 9- after an initial attack of schizophrenia.

Determinants of EE
At a given point in time, determinants of ployment; and cross-cultural differences in
the relative's degree of EE are likely to in- societal responses to the illness. The last of
clude the patient's behavior (degree of these factors is discussed by Jenkins et aI.,
disturbance and extent of secondary handi- in Chap. 3. With the exception of the pa-
cap); the relative's perceived ability to cope tient's behavior, none of these influences
and related problem-solving skills; idiosyn- on EE has been studied in a systematic fas-
cratic personality factors; the amount and hion, but relatives' accounts suggest that
quality of information available concerning each is of some importance and warrants
the illness; external stresses such as unem- further investigation.

EE: State or Trait?


An assumption throughout the EE investi- sponse appears to be a direct reaction to the
gations is that a high degree of EE on one patient's behavior when ill. (Brown's esti-
occasion "is a measure of the relative's pro- mate of 35% is in accord with the figures
pensity to react in that way to that particular which emerged from the content analysis of
patient, even though other factors may be criticism in the 1976 Vaughn and Leff
needed to precipitate this." (Brown et aI., study). In such cases, one would expect a
1972, p. 246). Thus, the EE level at the time good patient recovery with full remission of
of key admission represents a potential to symptoms to be followed by a lowering of a
respond in a characteristic manner, partic- relative's EE, particularly the number of
ularly at a time of crisis for the family. This critical comments. This is precisely what
tendency does not preclude fluctuations in happened in follow-up interviews conduct-
EE levels over time, however. These are ed by Brown et al. (1972) within a year of a
most likely to occur in the proportion of patient's discharge from the hospital. The
cases in which the relative's emotional re- number of criticisms made by relatives had
104 C. E. Vaughn
decreased considerably; the greatest reduc- be deep-rooted and hence less amenable to
tion in number occured with respect to pa- clinical intervention.
tients who had markedly improved. Thus, In both the London (1972) and Hamburg
the Hamburg results regarding the appar- follow-up studies, changes from low EE at
ent instability of EE (Chap. 5); are not in- admission to high EE at follow-up were un-
consistent with earlier findings. Other in- common. However, one can imagine cir-
dices of expressed emotion, such as emo- cumstances in which this direction of
tional overinvolvement (EOI), showed a change might occur: for example, the de-
less marked tendency to diminish over velopment of an increasingly pessimistic
time. These differential findings are con- view of the long-term prognosis when a pa-
sistent with clinical impressions of thera- tient fails to recover completely after a
pists who have attempted to modify levels single acute episode. In the absence of ap-
of EE. Apparently, it is easier to lower high propriate counseling or support, a relative
levels of criticism than to alter patterns of might easily become more anxious or more
marked EOI, which by their nature tend to critical, and EE levels rise accordingly.

Exceptional Response Styles: "Schizophrenogenic" Highs and


"Burnt-out" Lows
Because the main focus of EE investiga-; Nevertheless, a minority of relatives of
tions has been on schizophrenia, the risk re- schizophrenic patients - perhaps 15%, in
mains that the components of the EE index the author's experience - do display ex-
will be perceived to be specific to families of treme or bizarre response styles reminis-
that diagnostic group. It is worth reiterating cent of the "schizphrenogenic" stereotypes
that they are not. Criticism, hostility, and described in the past by Fromm-Reich-
emotional overinvolvement may feature in mann, Laing, Lidz, and others. These rela-
any relationship, and they have been shown tives are extraordinary individuals by any
to occur across a wide range of conditions criteria, especially memorable for the inter-
and cultures. Furthermore, while the dis- viewer because of the manner in which their
tinguishing characteristics of low EE and "stories" are told. They tend to be mothers
high EE relatives may be readily identified, and almost always score highly on EO!.
th!!re is considerable variation of response They mayor may not be highly critical as
within the dichotomized categories. Each well. It is not uncommon, however, for
family is different. Relatives obtaining simi- these relatives to score highly on all the key
lar scores on key EE scales do not neces- EE scales. The result can be a classic "dou-
sarily resemble each other, nor does any ble-bind" style of response in which signs
one relative display all the "markers" of of hostility toward the patient alternate
being high or low EE. Trainees in the use of with signs of warmth, and critical and posi-
the Camberwell Family Interview and the tive remarks are juxtaposed in the same
EE scales frequently express surprise at the passage. When there also is evidence of
ordinariness of many high EE respondents, communication deviance, the difficulties
particularly when the patient has a diagno- multiply for the interviewer/rater. One
sis of schizophrenia. Yet the majority of rel- wonders whether the resultant sense of con-
atives interviewed do seem to be "normal," fusion may not approximate, to some de-
whatever that word may signify nowadays. gree, the confusion experienced by the vul-
Reactions of extreme distress or anger are nerable patient exposed to such conflicting
often understandable, given the nature of messages. Almost certainly these high EE
the disorder and its sometimes grievous im- relatives pose problems of a special order
pact on family life. In the words of one rela- for the clinician hoping to influence the
tive, "It's all a very sad business, very sad." course of the illness by family intervention.
A high EE response by the relative usually There also exists a subgroup of low EE
is notable not for its own sake, but for its ap- relatives who do not fit the characteristic
parent impact on the vulnerable patient. low EE profile, i.e., who are not benign,
Patterns of Emotional Response 105
tolerant, mature individuals living in stable of their lives. For such persons, the identi-
households. The atypical low EE relative fied patient's schizophrenia represents just
has emerged fairly recently, in studies of another of a host of seemingly insoluble
large inner-city conurbations whose resi- problems. The positive characteristics usual
dents are economically and socially de- in low EE relatives are lacking. To date,
prived. In such families, a low EE response these "burnt-out" relatives are few in num-
may reflect apathy and indifference rather ber, but they may feature more prominently
than calm concern. These families tend to in future studies, particularly of popula-
be subjected to multiple stresses; they feel tions for whom rates of unemployment are
they have little or no control over the course high.

Conclusion: Some Implications for Clinical Intervention


In their efforts to cope with a serious psych- some respects an apt one; both present
iatric illness, most relatives claim to have management problems which can benefit
received little or no assistance from mental from a constructive, problem-solving ap-
health professionals. By their own ac- proach.
counts, the nature of the advice and infor- The particular qualities and coping abili-
mation provided has altered little over the ties of many low EE relatives deserve to be
years - the amount is negligible and the noted. The more positive and constructive
quality poor, in general. In the absence of elements of the low EE response style re-
professional guidelines, families tend to present behaviors which can be modeled in
manage on their own, more or less well. intervention programs with high EE fami-
The EE data suggest that mental health lies. Yet low EE relatives should not be
education is a basic imperative for all pa- neglected in such programs, for at least two
tients and their families. For both ethical reasons. Firstly, they too need advice, in-
and pragmatic reasons, they deserve to formation, and support. In the rush to iden-
know more about the disorder, medication tify "high-risk" households, there is a dan-
and its side effects, and other related issues. ger that the needs of those who appear able
In the 1976 British study, only half of the to cope will be overlooked. Secondly, the
relatives interviewed considered the pa- EE studies to date have been concerned
tient's schizophrenic illness to be a mental with one measure of outcome only: symp-
problem. Moreover, in all the schizophre- tomatic relapse. Other measures of out-
nia studies to date, highly critical relatives come, such as presence or severity of sec-
were significantly more likely than other ondary handicaps, were not attempted.
relatives to take an unsympathetic view of There is some evidence that when a low EE
the illness, i.e., to blame the patient for his relative has no expectations for a schizo-
symptoms and hold him responsible for not phrenic patient and exerts no pressure to
exercising control over them. It is essential perform, there may actually be an increase
that the persons most directly concerned - in negative symptoms and higher levels of
the patient and those around the patient - social impairment. Thus, home environ-
are involved in the treatment process from ment which is benign by one criterion may
the first psychiatric contact. If they are not, not be so by another.
then "administrative" solutions (such as the The existence of atypical high EE and
routine prescription of medication) to the low EE response styles further emphasizes
problems associated with relapse and read- the need to look beyond simplistic labels in
mission are likely to fail. Ideally, mental efforts to identify families who might bene-
health education for psychiatric consumers fit from direct clinical intervention. An EE
should become as commonplace as anten- index, or any other "risk" indicator, is of
atal care for pregnant women or counseling very limited use when it comes to planning
for persons who have diabetes. The analogy interventions. What are desirable - follow-
between schizophrenia and diabetes is in ing on from mental health education for all
106 C. E. Vaughn
- are treatment and rehabilitation pro- assessments of individual families' differing
grams which are based on comprehensive assets and needs.

References
Brown, G. W. (1959). Experiences of discharged I. R. H. (1983). Premorbid and symptomatic
chronic schizophrenic mental hospital patients characteristics of schizophrenics from families
in various types of living group. Millbank Me- with high and low levels of expressed emotion.
morial Fund Quarterly, 37, 105 - 13l. Journal of Abnormal Psychology, 92,359- 367.
Brown, G. W. (1985). The discovery of "ex- Miklowitz, D. J., Goldstein, M. J., Falloon, I. R.
pressed emotion": Induction or deduction? In H., and Doane, J. A. (1984). Interactional cor-
J. Leff and C. Vaughn (Eds.), Expressed emo- relates of expressed emotion in the families of
tion in families: Its significance for mental ill- schizophrenics. British Journal of Psychiatry,
ness. New York: Guilford. 144,482-487.
Brown, G. W., Birley, J. L. T., and Wing, J. K. Vaughn, C. E., and Leff, J. P. (1976). The in-
(1972). Influence of family life on the course of fluence of family and social factors on the
schizophrenic disorders: A replication. British course of psychiatric illness: A comparison of
Journal of Psychiatry, 121, 241-258. schizophrenic and depressed neurotic patients.
Brown, G. W., Carstairs, G. M., and Topping, British Journal of Psychiatry, 129, 125-137.
G. G. (1958). The post-hospital adjustment of Vaughn, C. E., Snyder, K. S., Jones, S., Free-
chronic mental patients. Lancet, 2, 685-689. man, W. B., and Falloon, I. R. H. (1984).
Leff, J. P., and Vaughn, C. E. (1985). Expressed Family factors in schizophrenic relapse: Replic-
emotion in families: Its significance for mental ation in California of British research on ex-
illness. New York: Guilford. pressed emotion. Archives of General Psychi-
Miklowitz, D. J., Goldstein, M. J., and Falloon, atry, 41,1169-1177.
B. Modification of the Course of Schizophrenia
by Family Interventions
9. Working with Families of Acute Psychotics:
Problems for Research and Reconsideration
L. C. Wynne

My observations of acute psychotics and be definitively diagnosed when first seen.


their families in recent years lead me to pro- Hence, all functional psychoses were pro-
pose that educational programs and other visionally included except clear-cut manics
forms of intervention with the families of or psychotic depressives. Patients with a
these patients need to be given much more history of use of street drugs or alcohol
distinctive consideration. Although much could be included provisionally if there was
that we have learned about educational evidence that these substances were not the
programs with families of chronic schizo- primary or major cause of the episode. In
phrenics is relevant, the programs with Rochester, we fortunately have a psychia-
families of acute, first-admission psychotics tric care system in which essentially all acute
should be significantly different. psychotics in our catchment area have been
My current thinking about these pro- funneled by families, doctors, and com-
blems has arisen since 1978 when Dr. Tho- munity agents (such as the police) into the
mas Gift and I, and our associates in Ro- Emergency Department (ED) ofthe Strong
chester, began to participate in the WHO Memorial Hospital. The ED, then, is the
Study of the Determinants of Outcome of established point of first contact for essen-
Servere Mental Disorder (DOS). Patients tially all of these patients in this catchment
selected for this study differed from those area.
with whom I had worked in earlier years at In sharp contrast to my experience in
NIMH and in Rochester. In the Interna- Washington and to prior studies in Roches-
tional Pilot Study of Schizophrenia (IPSS) ter with chronic patients and their families,
(WHO, 1973), in which I participated at these first-admission acutely psychotic pa-
NIMH, patients were selected only with the tients and their families in the DOS present-
very broad stipulation that the onset was to ed a new array of issues and problems.
be within 5 years of admission. The catch- First, the patient regularly defied diagnostic
ment area from which the patients were classification, even with DSM-I1I (1980).
selected was broad and loosely defined. In As Fox (1981, p. 63) has said in a British
no sense could the study be regarded as one perspective on DSM-III:
of epidemiologic incidence, even treated The least satisfactory aspect of the DSM-III
incidence. The DOS selection criteria were treatment of the psychoses is the classification of
much more rigorously defined by limiting those acute and episodic disorders with features
the sample to a specific, geographically de- of both schizophrenia and affective disorder. By
assigning most such disorders to schizophrenia or
fined catchment area, with the expectation
affective disorder, DSM-III may obscure the un-
that each first-admission patient in that certainty surrounding such patients, and diminish
catchment area would be consecutively in- the possibility of further clarifying their corre-
cluded if he or she met screening require- lates.
ments for functional psychosis. Further- Indeed, most of these patients do have stri-
more, the first outpatient psychiatric con- king affective features, in addition to the
tact for psychotic symptoms had to occur presence of hallucinations, delusions, or in-
within the previous 3 months. Although the coherence that is used to define psychosis
primary focus was on schizophrenia, such operationally. Although DSM-III is inade-
acute psychotic patients obviously cannot quate for classification of acute psychoses,
110 L. C. Wynne
the British approach, building upon Present tion within hours of arrival in the ED left us
State Examination (PSE) data and uncertain about our diagnostic assessment
CATEGO (Wing, Cooper, and Sartorius, and dissatisfied as to whether our standard
1974), is, in my view, even more unsatisfac- criteria were consistently relevant. There-
tory for these patients. If one faces these fore, in 1981, we successfully changed the
diagnostic dilemmas squarely, educational admission procedure so that we now are
programs with the patient's families need to called directly by a nurse in the ED about
acknowledge this uncertainty and recognize any patient broadly meeting our selection
that the relatively explicit diagnostic criteria criteria. We ourselves see the patient in the
and treatment and outcome data used in emergency setting before any other psychi-
programs with the families of chronic schi- atrist has done so. We then follow up with
zophrenics simply are not available for control over our own program of clinical
acute psychoses. care and treatment within the framework of
Second, the very fact of the acuteness of the WHO research program and do not
the episode, and especially the fact that this need to "wash out" the often confusing ef-
is the first such episode, clearly makes for a fects of various medications.
very different impact upon the family com- While in the ED, we are able to meet per-
pared with the experience of families who sonally with the family members and to be-
have lived through several episodes and re- gin immediately the process of support and
hospitalizations over many months or education at a time when the family is
years. highly receptive and grateful for attention.
Third, the way that the families reorgan- This process also facilitates the task of in-
ize themselves internally and in relation to teresting the family members a little later in
the support network evolves over time for participating in the Camberwell Family In-
the families of the chronic patients in a way terview (CFI) (Vaughn and Leff, 1976) and
that is structurally quite different than for our other family research procedures.
families of first-episode psychotic patients. Although I have been using the PSE since
Thus, the ease and appropriateness offam- 1965, when it was in an early edition, I have
ily changes inevitably differs for families of become concerned, especially in. our work
recurrent or chronic versus first-admission, with acute psychotics, by the inadequacy of
acutely psychotic patients. I shall return to this instrument for a broad spectrum of
each of these points later, together with acute psychoses. First, the PSE and the
some preliminary comments on family in- CATEGO system associated with it rely
tervention programs with the families of heavily on Schneiderian first-rank symp-
acute patients. toms. These symptoms formerly were as-
Misdiagnoses of patients inevitably pro- sumed to be quite diagnostic of schizophre-
duce misunderstanding of the family's ap- nia and were incorporated into the DSM- III
propriate contricution to the patient's with this viewpoint still in mind. However,
treatment. Research psychiatrists typically the analysis of diagnostic data, by Carpen-
do not see acute psychotics until after a psy- ter and Strauss (1974), Brockington, Ken-
chiatric resident or attending psychiatrist dell, and Leff (1978), and others, have fully
has first interviewed, diagnosed, and treat- documented the inadequacy of the Schnei-
ed the patient. Initially in Rochester, Dr. derian symptoms for diagnosing schizo-
Gift and I usually were able to see the acute phrenia. This is much more of a problem
psychotics quickly, within 24-48 h after ad- with acute psychotics than with chronic pa-
mission. Even so, we were the second or tients because the Schneiderian features are
third, not the first, to do so, and at that time found in most patients, schizophrenic or
we did not determine the treatment. We not, when they are floridly psychotic, espe-
were impressed by the frequency with cially those with marked affective features.
which important florid symptoms had al- A second problem with the PSE is the
ready disappeared or had been trans- lack of items relevant to affective psycho-
formed, either by medication or by the hos- ses. We had had to use supplementary items
pital admission process. Most importantly, to cover these areas in our Rochester re-
the administration of neuroleptic medica- search.
Working with Families of Acute Psychotics 111
Third, most acute psychotics have vivid than do older manics. Recent, unpublished
paranoid delusions that are strongly weight- observations by L. Crabtree (personal com-
ed on the PSE to produce a CATEGO diag- munication, 1982) in Philadelphia (which
nosis of paranoid schizophrenia. Since par- are concordant with my own observations)
anoid delusions (and hallucinations) are suggest that many acting-out adolescents
prominent in mania and even hypomania, and young adults with impulsive, assaul-
these CATEGO diagnoses are often in er- tive, and often disorganized behavior are in
ror. Helzer, Brockington, and Kendell fact mancis. They are subdued by neuro-
(1981) have found the CATEGO wanting leptics but otherwise do poorly with these
as a predictor of outcome. drugs, although they respond well to lithi-
At the same time, not only the CATE- um. Some are further benefited, especially
GO, but also other diagnostic classifica- if they have had a developmental disorder,
tions, excepts in the Scandinavian classifica- in focusing their attention through use of
tion system, clearly underestimate the like- tricyclic antidepressants, which have a
lihood that a diagnosis of reactive psychosis paradoxical effect in this age range similar
or psychogenic psychosis will be made. The to amphetamines in the treatment of hyper-
category of schizophreniform disorder in active children.
DSM-III requires the characteristic An additional problem for diagnosis and
(Schneiderian) symptoms for schizophre- intervention arises because some of the
nia, but at the same time fails to allow for acute psychoses arise from a baseline of
the distinctively different symptoms, most- severe personality disorders. Here a very
ly affective, and the differing course and important distinction will need to be made
precipitants that are found in the "reactive between those who have had a schizo typal
psychoses," "psychogenic psychoses," and personality disorder, usually with a poor
"benign schizophreniform psychoses," as premorbid adjustment, and those with a
they have been labeled in Denmark (WeI- "borderline" personality disorder, which
ner and Stromgren, 1958; McCabe, 1975). often appears to be part of the affective
By now it is commonplace to recognize spectrum. The latter patients are more apt
that American psychiatrists of 10-20 years to have transient psychotic episodes than
ago diagnosed schizophrenia loosely and are the schizotypal and schizoid patients.
much more frequently than did the British. A still further complication to the di-
As a turnabout, affective psychoses may agnostic problem with acute psychotics con-
now be diagnosed more frequently in Ame- cerns the effects of street drugs. There do
rica than they are in Britain. Although seem to be marked differences in the sex
these changes in diagnostic habits may lead distribution of acute psychotics, which may
to gains in the long run, confusion about the reflect in many settings the greater use of
acute picture remains, especially when eval- substance abuse in males. Recent evidence
uated from hospital records. First-admis- suggests that not only marijuana but also
sion records of patients who are now chron- PCP and LSD become bound in the tissues
ic and of family members hospitalized in the through chemical mechanisms and are re-
past are of dubious value for establishing a leased to produce recurrent flashbacks that
valid family history. Many American rec- clinically are often indistinguishable from
ords fail to mention the affective status of functional, acute psychotic episodes. Taka-
manics when delusions or hallucinations hashi (1982) has told me that Japanese data
have been reported so that the affective suggest that psychotic relapses may occur
aspect of the clinical status is often unclear. on this basis, without additional ingestion
Another shift has occurred through the of street drugs, for as long as 2 years; he is
belated recognition that manic-depressive quite convinced that this phenomenon may
illness often begins in adolescence and account for the remitting and relapsing
young adulthood. In the past, manic-de- qualities for some of the allegedly schizo-
pressive illness was ruled out in many clinics phrenic psychoses.
if the patient was less than 25 years old. The nature of psychoeducational pro-
These younger manics, especially males, grams with families will of course need to
often present with a rather different picture vary considerably with the nature of the ill-
112 L. C. Wynne
ness of the identified patient. Whether or believe are primary in schizophrenia,
not all of the points that I have raised above though admittedly difficult to delimit, schi-
about diagnosis are confirmed by further zophrenia is a nonremitting disorder. It is,
research, it seems clear that a definitive di- of course, useful to forestall relapse of the
agnostic assessment will remain difficult in florid symptoms, but in the home and com-
early stages of acute psychoses and that an munity, the deficit symptoms are most
educational program oriented to just one troublesome. This includes what Wynne
disorder (schizophrenia) may be misleading and Singer (1963) have called "amorphous"
for the family. forms of communication. Special attention
In years past, experimental psychologists to the issues of building compensatory so-
have given considerable emphasis to the cial skills, in the family setting and else-
concept of process schizophrenia versus re- where, is important with these families.
active schizophrenia. Many data have sup- However, with the families of acute psycho-
ported the idea that process schizophrenics, tics, only those with a long prodome and
with poor premorbid personality, insidious poor premorbid history need to have this
onset, and poor outcome, have core psy- emphasis.
chological deficits, particularly in the at- Diagnostic distinctions of the kind I am
tentional sphere. For many years, Strom- making here should facilitate more focused
gren (1965) and other Scandinavians have interventions with both patient and family.
recommended that the so-called good prog- Most importantly, I believe that we must
nosis schizophrenics, or what Vaillant take seriously this distinction between nu-
(1964) calls the remitting schizophrenics, be clear schizophrenia, as I have just described
more fully separated from the nuclear or it, and good prognosis schizophrenia, which
nonremitting schizophrenics. This view- may be better regarded as a form of affec-
point is now being explored in relation to tive disorder or, as McCabe (1975) has sug-
ventricular enlargement found in CT scans gested, as a third major type of disorder dif-
of different categories of patients (Wein- fering from both schizophrenia and manic-
berger, De Lisi, Perman, Targum, and depressive psychosis. If my gloomy view of
Wyatt, 1982). Strauss and Carpenter (1974) the outcome of nuclear schizophrenia is
have shown that poor premorbid adjust- justified, much of what is included in pre-
ment is associated with poor postmorbid sent-day family educational programs, such
adjustment, particularly in the social and as those of Anderson, Hogarty, and Reiss
occupational sphere. It appears that the (1980), will still be quite appropriate. On
poor premorbid and prodromal symptoms, the other hand, programs with acute psy-
such as social withdrawal, selectively pre- chotics who mayor may not be on their way
dispose to later negative or deficit symp- to nuclear schizophrenia will need to be
toms after a florid episode. What have been planned with much more discretion and
called the "characteristic," florid symptoms with a different orientation. It is crucial to
of schizophrenia are actually not so charac- consider this diagnostic distinction even in
teristic because they also are found in other the present day when more emphasis is
florid psychoses. The longitudinal se- given to affective psychoses because the
quences of florid symptoms preceded by, acute phase of illness is still inadequately
and followed by, deficit symptoms make a understood and is quickly masked in most
more definitive basis for the diagnosis of settings by large doses of neuroleptics. It is
schizophrenia. indeed rare to find a setting in which even a
My present view is that it would be desir- week of diagnostic study with nonmedic-
able to spell out still more than does DSM- ated care is available for acute psychotics,
III the following limitations for the di- despite the fact that Carpenter, McGlas-
agnosis of schizophrenia: The florid (posi- han, and Strauss (1977) clearly showed that
tive) symptoms remit and relapse, but the such care is possible for even longer pe-
deficit (negative) symptoms persist with riods.
only minor improvements and are inade- Beyond the immediate diagnosis, the
quately documented in DSM-III. From the heavy use of neuroleptics also leads to mis-
standpoint of the deficit symptoms, which I interpretation of deficit symptoms. All too
Working with Families of Acute Psychotics 113
often, the deficit symptoms that follow a plicitly designed to be a neutral research
florid episode are viewed as requiring larger procedure. Indeed, a good therapist at that
doses and longer duration of medication. crisis stage would handle the situation in a
Many patients who have been heavily me- very similar manner. Increasingly in Roch-
dicated for months or years, show side ef- ester, we have been finding that the CFI can
fects that blur with the deficit symptoms of usefully be integrated into the clinical pro-
the illness. I wish it were true that this kind gram and should not be labeled and put out
of problem only occurs with therapists who of sight as data only for the researcher.
are inexperienced or incompetent, but I 3. After preliminary meetings with the
fear that the problem is, in fact, far more relatives, without the patient present,
widespread. meetings with the whole family (including
What are the details of family interven- the patient) are nearly always useful, at the
tion and educational programs that can be very least to take stock of their future to-
useful with the families of acute psychotics? gether. Some family therapists have recom-
My suggestions here are highly preliminary mended against having patients meet with
and tentative, and they can by no means their families during the so-called florid
cope with all of the complexities that I have phase, perhaps because they fear that this
noted above. will evoke high expressed emotion from the
1. The interventions with both patient family (Vaughn and Leff, 1976). If the in-
and family need to be carried out most in a terviewer takes a firm, structuring position
phase-oriented manner (Wynne, 1983), be- and adapts the length of the family meeting
ginning at the first psychiatric contact, to the functioning of those present, I have
when the family typically brings the patient found that these difficulties, when they do
to the psychiatric facility. Perlmutter (1983) occur, are quite manageable. Such meetings
at the Strong Memorial Hospital in Roches- can be quite helpful in assessing the family
ter collected survey data from the ED staff relationships along dimensions (especially
for 1000 consecutive patients. The data spe- structured) that are not so fully evident
cified whether or not family members came from individual interviews or test situa-
with the patient and whether the patient's tions. However, I do not automatically con-
central presenting problem was about a tinue with conjoint interviews when assess-
family difficulty; 700 of the 1000 patients ment indicates this seems unworkable or
were thus involved with their families at the unrealistic.
time of the emergency contact. Dismaying- 4. The concept of psycho educational
ly, relatively few families were seen at that workshops similar to those used with fami-
time. As I have indicated, when the families lies of chronic schizophrenics need to be
are brought into the picture and viewed as modified for families of acute psychotics. I
assets and resources for both the ongoing am intrigued by a recent innovation by
clinical care and for future planning with Crabtree (personal communication, 1982)
the patient, their subsequent cooperation is in which he introduced five successive even-
much more likely. As Scott (1976) has ing workshops, a week apart, with parents
shown, a psychological closing off by the of four to five families, each having a psy-
family from the patient is greatly reduced if chotic offspring in the 18- to 25-year-old
the family is contacted within 72 h of admis- range. They spend one session each on schi-
sion and brought into the treatment plan- zophrenia, affective psychoses, borderline
ning. problems, street drugs and therapeutic me-
2. A crisis intervention approach with the dication, and developmental-life cycle is-
family is appropriate in the subsequent sues. This explicity educational program
days. Surely, acute onset of psychosis in a leads, as in the experience of most others
family member is experienced as a crisis. As who have carried out educational pro-
in other crisis intervention, the family needs grams, into frequent requests for more ex-
time to talk over and to ventilate their feel- tended family therapy, which may be on a
ings of perplexity, frustration, and anger. group or on an individual basis.
The CFI often serves a useful therapeutic Thus far, I have seen these families one at
purpose of this kind, even though it is ex- a time, rather than in multiple-family
114 L. C. Wynne
groups. I label several meetings as educa- times to make sure that the staff member
tional and informational, set apart as not was available, is useful. With the families of
having explicit therapeutic intent. How- acute psychotics, compared with the fami-
ever, I now regard education as a funda- lies of chronic patients, the kinds of ques-
mental component of all the family therapy tions that are raised and the kind of anxiety
that I do. An advantage in Crabtree's ap- and alarm are quite different. The families
proach of discussing a series of disorders, of chronic patients are often focused on
rather than the one disorder presumed to be themselves. They are inclined to blame
diagnostic for an identified patient, is that themselves or, more usually, feel blamed
the diagnostic complexity is conveyed at a and neglected by the psychiatrists, all too
sensible, understandable level, which the often with justification. In contrast, the
families seem to value highly and do not fall families of first-admission patients are more
so easily into demands for premature cer- inclined to look for "the problem" in pos-
tainty. sible marijuana usage, bad companions, or
5. Later follow-up will vary tremendously in some life event, and only rarely wonder
with the diverse problems, and with their whether something within the family may
course. Even when the diagnosis later is nu- be relevant. Nevertheless, these families of
clear schizophrenia, early intervention of acute psychotics are in a crisis; they are dis-
this kind continues to prove helpful in eas- tressed; and they are responsive to those
ing the burden on the family as a unit, and, who will listen to them and who will re-
in tum, helping the family to realize its po- spond with information and guidance. A
sitive capabilities in facilitating treatment. major task for the future in the field of pre-
My recent experience strongly indicates vention lies in developing early support and
that the willingness of families during and educational programs for the families of
after a first admission to be interested in ex- acute psychotics. These programs require
tended programs of this kind is quite dif- careful design and are not so easily organiz-
ferent from that of families of chronic pa- ed in a standard format as with the families
tients. Although the work with families of of chronic schizophrenics. Nevertheless,
chronic patients may not be continuous, in- the payoff in preventive success may be in-
termittent contact with family members, deed high.
sometimes about a new problem, some-

References
Anderson, C. M., Hogarty, G. E., and Reiss, D. ington, D. C.: American Psychiatric Associa-
J. (1980). Family treatment of adult schizo- tion.
phrenic patients: A psychoeducational ap- Fox, H. A. (1981). The DSM-II1 concept of schi-
proach. Schizophrenia Bulletin 6: 290-505. zophrenia. British Journal of Psychiatry 138:
Brockington, I. F., Kendell, R. E., and Left, J. 60-63.
P. (1978). Definitions of schizophrenia: Con- Helzer, J. E., Brockington, I. F., and Kendell,
cordance and prediction of outcome. Psycho- R. E. (1981). Predictive validity of DSM-II1
logical Medicine 8: 387-398. and Feighner definitions of schizophrenia: A
Carpenter, W. T., McGlashan, T. H., and comparison with research diagnostic criteria
Strauss, J. S. (1977). The treatment of acute and CATEGO. Archives of General Psychia-
schizophrenia without drugs: An investigation try 38: 791-797.
of some current assumptions. American Jour- McCabe, M. S. (1975). Reactive psychoses: A
nal of Psychiatry 134: 14-20. clinical and genetic investigation. Acta Psychi-
Carpenter, W. T., and Strauss, J. S. (1974). atrica Scandinavica, Supplement 259: 13-133.
Cross-cultural evaluation of Schneider's first- Perlmutter, R. A. (1983). Family involvement in
rank symptoms of schizophrenia: A report psychiatric emergencies. Hospital and Com-
from the International Pilot Study of Schizo- munity Psychiatry 34: 255-257.
phrenia. American Journal of Psychiatry 131: Scott, R. D. (1976). Closure in family relation-
682-687. ships and the first official diagnosis. In J. J(Ilr-
DSM-II1. (1980). Diagnostic and Statistical stad and E. Ugelstad (Eds.), Schizophrenia 75,
Manual of mental disorders (3rd ed.). Wash- pp. 265-281. Oslo: Universitetsforlaget.
Working with Families of Acute Psychotics 115
Strauss, J. S., and Carpenter, W. T. (1974). The Archives of General Psychiatry 39: 778-783.
prediction of outcome in schizophrenia: II. Re- Weiner, J., and Stromgren, E. (1958). Clinical
lationships between predictor and outcomc and genetic studies on benign schizophreni-
variables: A report from the WHO Intcrnat- form psychoses based on a follow-up. Acta Psy-
ional Pilot Study of Schizophrenia. Archives of chiatrica et Neurologica Scandinavica 33:
General Psychiatry 31: 37-42. 377-399.
Stromgren, E. (1965). Schizophreniform psycho- World Health Organization. (1973). The Inter-
ses. Acta Psychiatrica Scandinavica 41: national Pilot Study of Schizophrenia, Vol. 1.
483-489. Geneva: World Health Organization.
Takahashi, R. (1982). Personal communication. Wing, J. K., Cooper, J. E., and Sartorius, N.
Vaillant, G. E. (1964). An historical review of (1974). The measurement and classification of
the remitting schizophrenias. Journal of Nerv- psychiatric symptoms. Cambridge: Cambridge
ous and Mental Disease 138: 48-56. University Press.
Vaughn, C. E., and Leff, J. P. (1976). The in- Wynne, L. C. (1983). A phase-oriented approach
fluence of family and social factors on the to treatment with schizophrenics and their
course of psychiatric illness: A comparison of families. In W. R. McFarlane (Ed.), Family
schizophrenic and depressed neurotic patients. therapy in schizophrenia, pp. 251-265. New
British Journal of Psychiatry 129: 125-137. York: Guilford.
Weinberger, D. R., DeLisi, L. E., Perman, G. Wynne, L. c., and Singer, M. T. (1963). Thought
P., Targum, S., and Wyatt, R. 1. (1982). Com- disorder and family relations of schizophrenics:
puted tomography in schizophreniform dis- II. A classification of forms of thinking. Ar-
order and other acute psychiatric disorders. chives of General Psychiatry 9: 199-206.
10. Family Education as a Component
of Extended Family-Oriented Treatment
Programs for Schizophrenia
L. J. Cozolino and 1\1. J. Goldstein

Introduction
The desire for knowledge in relatives of beginning to evaluate family education, it
schizophrenic patients has stimuled the de- seems appropriate to start with such pro-
velopment of long-term intervention pro- grams because of the wealth of information
grams which include an initial phase of fam- that is available from the broader research
ily education. The present paper reviews project. This context allows us to have an
four family intervention programs designed accurate understanding of the information
for these relatives, which were summarized made available and the type of information
in a recent volume (Goldstein, 1981). These and treatment received by the patient and
programs were developed in the context of provides an opportunity for direct assess-
clinical research studies headed by Falloon ment of the interpretation and utilization of
and Liberman in Los Angeles, Leff and his information and practical management ad-
associates in England, and Anderson and vice.
Hogarty in Pittsburgh. Each program con- While all of these programs attempt to
tains a component specifically designed to delineate a family education phase from a
transmit some basic information about schi- long-term intervention phase, it is impor-
zophrenia and to answer questions concern- tant to note that long-term interventions
ing diagnosis, etiology, prognosis, and the have the opportunity to continue the edu-
relatives' role in the recovery process. cational process throughout the treatment
Family and patient education programs periods which range from 9 weeks with a 3-
did not begin with these newer family inter- month follow-up (Snyder and Liberman,
vention programs but have been developed 1981) to 2 years (Falloon, Boyd, McGill,
during the last 20 years throughout the Uni- Strang, and Moss, 1981). Thus, it is some-
ted States, Canada, and England in both what arbitrary to delineate an "educational
medical and community settings. They have component" in isolation from the rest of the
grown with the support of physicians, thera- program. In all of these programs, the edu-
pists, community workers, and family mem- cational component can be interpreted as a
bers to serve the needs of relatives and to seeding process or as an opportunity to be-
explore ways of getting information and gin with a common language and set of as-
support to a wide audience. Information is sumptions rather than expecting to transmit
delivered in many forms, ranging from information which will be understood and
books, pamphlets, and daylong courses to used by itself. In subsequent group meet-
being transmitted as part of ongoing family ings, Berkowitz, Kuipers, Eberlein-Fries,
therapy programs or mutual support or- and Leff (1981) found that although many
ganizations. The family education pro- participants seemed to need to hear the in-
grams analyzed in this paper have drawn formation given during the educational
heavily on this prior work. component a number of times, it did seem
The four family education programs out- " ... to have served the purpose ... of help-
lined in this paper are part of long-term ing relatives formulate questions that they
family intervention programs established may not have been able to ask before."
for research purposes in medical settings. In (p. 38). All program descriptions stress the
118 L. J. Cozolino and M. J. Goldstein
importance of exercising a great deal of ficacious methods of transmitting informa-
flexibility in both the educational and long- tion to the families has yet to be done. It is
term intervention phases because of the hoped that this comparison will serve as a
individual needs of particular families. starting point in the delineation of research
Because this is a relatively new move- questions to be addressed in the future de-
ment, systematic assessment of the most ef- velopment of family education programs.

Comparison of the Four Programs


To appreciate similarities and differences in to engage in behavior modeled for them by
the family education component in each of the low EE group members. This was a dif-
the four programs, it is necessary to have ficult process, and the groups tended to take
some overview of the total, extended pro- on the qualities of "support, catharsis, en-
gram in which each is embedded. There- couragement, and interest." Overinvolved
fore, in this section we will first present a relatives were also encouraged to find inter-
brief summary of each of the programs ests in areas other than the patient. Mem-
which presents the underlying rationale and bers often discussed information about
a short description of each of the different schizophrenia, management issues, and
phases of the program. The brief summa- their feeling about the entire process.
ries are based on program descriptions pro-
vided by these investigators in the Gold-
Liberman and Snyder
stein (1981) monograph on this subject.
Based on the premise of an interrelation-
ship between EE and psychophysiological
LefT, Berkowitz, and Knipers
arousal, Liberman and Snyder hypothesize
This program is the most specifically fo- that relapse in a biologically vulnerable in-
cused toward lowering expressed emotion dividual is a result of a balance between life
(EE) in the home and reducing the amount stressors and problem-solving skills. Too
of direct contact between the patient and much environmental stress (for example,
the family. The first component of the pro- an overly critical or involved family) and/or
gram is the joint interview, which takes too few coping skills may lead to relapse.
place as soon as possible after the patient's Thus, the emphasis here, as in the Leff et al.
discharge from the hospital. This interview program, is on improving interactive coping
consists of a meeting with the family, pa- strategies used by family members and pa-
tient, a psychologist, and a psychiatrist to tients, instead of on emphasizing reduction
discuss ways of reducing contact and to cov- of contact.
er specific areas of conflict. There may be Thus, families in which most members
one or more of these interviews during the were rated as high in EE were admitted to
next 9 months taking any form which is the program. The first two sessions were
helpful to the particular family. family and patient education, which focus-
Mental health education was introduced ed on information about schizophrenia and
on the basis of research which suggested its effects on both the patient and the fami-
that high EE families tended to attribute ly. Practical information on the use of re-
the patient's behavior to deliberate acts sources in the hospital and community were
while low EE families attributed the pa- also discussed.
tient's behavior to the illness. It was felt that The final seven sessions took the form of
the more information the family had about joint therapy for relatives and patients, de-
schizophrenia, the better they would be signed to address specific communication
able to cope with the patient and to keep and problem-solving skills which could as-
down their level of EE. sist the family during the recovery period.
The group meetings for relatives were de-
signed to bring together low and high EE
families and to encourage high EE families
Family Education as a Component of Treatment 119
Anderson, Hogarty, and Reiss Falloon, McGill, and Boyd

Similar to the Liberman and Snyder pro- Two initial home sessions comprise the
gram in theoretical assumptions, Anderson family education component of treatment
et al. base their model on research in which take place with the patient present.
arousal/attention dysfunction and deviant Interaction and sharing are encouraged be-
family communication as well as on re- tween the patient and their family. Thera-
search on EE. pists often return to education later during
Anderson et al. introduce certain social therapy as the need arises.
work concepts, stressing a period of con- Family education and therapy are con-
necting with the family, which the other ducted in the home, which increases atten-
programs do not emphasize. Anderson dance and is thought to improve the gener-
et al. also refer to their daylong educational alizability of behavioral interventions. The-
component as a survival skills workshop for rapists are on 24-h call.
relatives, which underscores their emphasis This program is the most behaviorally
on pragmatic, day-to-day issues of coping oriented program reviewed here. Assess-
and management. Their overall goal is to ment begins with a behavioral analysis of
increase the predictability and stability of each individual and then of the family
the home environment, to increase adher- group. The interviewer attempts, through
ence to medication, and to provide support this process, to define a number of core
for the family, as well as the patient, communication and problem-solving defi-
through the recovery process. cits which become the focus of the com-
Like the Berkowitz et al. project, there is munication and problem-solving training.
a strong emphasis on the use of support Consistent with behavioral theory, assess-
groups and on the expansion of the family ment is carried on throughout the process,
and the patient's social support network. and the specific behavioral interventions
Their interventions focus on present prob- can be subsequently modified to meet new
lems during family therapy, postponing or changing needs.
long-term issues until after the immediate The Falloon et al. program is perhaps the
crisis of the schizophrenic episode is resolv- most extensive of all the approaches in
ed. While family therapy in this program terms of actual family involvement and
does not appear to be explicitly behavioral length of treatment, with 40 family sessions
in orientation, it does seem to be pragmatic being held over a 2-year period. Sessions
and problem focused. Communication are conducted in the home for the first 9
skills and problem-solving skills are pre- months and are either continued through
sented in a less structured manner than in the next 15 months or the family has the
the more behaviorally oriented programs. option of participating in community-based
family groups. Monthly medication evalua-
tions are conducted with the patient.

When, Where, and to Whom is Family Education Provided?


Next, we will focus upon the specific educa- of families present, whether the patient is
tional unit, variously termed mental educa- present or not, and the style of presenta-
tion, family education, or survival skills tion.
workshop, in which family members, some- It can be seen that the number of sessions
times with and sometimes without the pa- ranged from one to three and that they var-
tient present, are offered information about ied from relatively brief sessions to the all-
schizophrenia within a didactic format. day format of Anderson's group (Ander-
Table 1 presents a schematic of each of son, Hogarty, and Reiss, 1981). Mostly,
these educational components which pre- these programs begin while the patient is in
sents details concerning the lengths and the hospital or shortly thereafter when the
number of sessions, the location, member patient has been stabilized on medication as
120 L. J. Cozolino and M. J. Goldstein
Table 1. Overview of Psychoeducational Programs

Research No. of Length of Location No. of Patient Timing of Style of


group sessions sessions families present education presentation
present
Berkowitz 2 No set Hospital 1 No After Brief textis read to
etal. (1981) length or home patient participants and
discharge given to them to
take home, ques-
tionsare
answered
Snyder 2 2h Storefront 3 patient Yes During hospi- 3 co-leaders jointly
and Liber- and their talization, lead 1st h and then
man (1981) families most after a separate into in-
few weeks dividual therapy
groups, structured
syllabus, class-
room format -
handouts and
homework
assignments
Anderson, 1 5h Hospital 3-4fam- No Early in treat- Seminar structure
Hogarty, ilies ment,most - lecturelhand-
and Reiss patients still in outs
(1981) hospital
Falloon, 2or3 Phh Home 1 family Yes When patient At-home discus-
Boyd, is (re )stabiliz- sion where family
McGill, ed on medica- members are
Strang, and tion asked to share
Moss their experiences
(1981) and the patient is
encouraged to
discuss personal
and interpersonal
experiences

in the Falloon et al. program (Falloon, Participation of the patient at this point may
Boyd, McGill, Strang, and Moss, 1981). not be fortuitous, and family members may
The programs do differ in one important need an opportunity to consider matters in
factor and that is whether the patient is pre- a less emotionally charged context. In the
sent or not at these educational settings. In Falloon project, the patient has been dis-
two of the programs they are and in two charged and stabilized on medication for
they are not. One ofthe key issues for future 4-6 weeks before family education is car-
investigation is whether this particular com- ried out in the home with only the patient
ponent of a family program is inhibited or and significant relatives present. Is it the
facilitated by patient participation. This is level of remission, the home context, or the
not as simple an issue to resolve as it might focus on the single family unit that deter-
seem as the programs outlined in Table 1 mines the patient's participation? Some of
vary considerably in important parameters the projects use a group format while
which would affect the value of patient par- others, such as Leff et al. and Falloon et aI.,
ticipation. For example, the Anderson meet with an individual family unit. In
et al. family education program (survival what way do these contextual factors affect
skills) begins shortly after the patient is ad- the impact of a family education unit, if at
mitted to the hospital and still very psychotic. all? Further research is needed to clarify
Family Education as a Component of Treatment 121
whether the timing, group composition, or tape. An issue not clarified in Table 1 is that
site (home vs clinic) affect the impact of a in each of the treatment programs the fami-
family education program. ly education program was delivered, in
Note that those programs that involve part, by one of the persons who was involv-
relatives only do not appear to provide sep- ed in the longer term family program. Thus,
arate education for the patient. It remains it was not simply a case of a mental health
to be demonstrated whether separate pro- professional imparting information and
grams targeted specifically toward patients withdrawing from future contact from the
will enhance the impact of the programs family. Any future research on the impact
directed at the relatives. of these family education programs needs
To date, none of these family education to consider not only the issue of live vs
units have been prepared for mass media videotape format, but whether the person
distribution to be utilized in other settings. or persons who provide the information are
Clearly this represents a distinct possibility likely to be involved in the subsequent sup-
as there has been sufficient experience with port provided to the families who receive
the administration of these programs that the family education.
scripts could be created and put on video-

Content of the Various Family Education Programs


The informational contents of the family ties and differences of information given
education component across the four pro- across programs. Instead we felt it would be
grams have a great many similarities. There more informative to offer to the reader a
are many common features in that they all general outline of information given in the
deal with (a) definitions of a schizophrenic areas of diagnosis, symptomatology, etiol-
disorder, (b) a description of the various ogy, course, and treatment and to include
symptoms, (c) present theories about etiol- short passages from the various syllabi to
ogy and prognosis, and (d) treatment re- give a flavor of each program. If the reader
commendations concerning pharmacother- is interested in developing a program at her/
apy and family impact. The overlap be- his own facility, the authors strongly sug-
tween programs is not due to chance as a gest contacting these programs for more
number of investigators worked together in complete syllabi and information.
London at one time (Leff, Liberman, and Please note that while passages are taken
Falloon), and Hogarty had contact with from the syllabi or written materials offered
these investigators in the course of develop- from these programs, at the time of writing
ing his program with his colleague, Carol this report the syllabus from the Anderson
Anderson. While the nature of the informa- et al. program was not available, and pas-
tion across programs is relatively constant, sages are taken from a videotape of their
the manner and detail in which it is present- survival skills workshop.
ed varies a great deal. The Leff et al. project
keeps factual information to a minimum, Diagnosis
while the Falloon and Liberman programs
contain a great deal of factual information All of the programs begin with a discussion
which is presented at a fairly sophisticated of the diagnosis of schizophrenia, which
level. The Anderson program lies some- usually includes common misconceptions
where in the middle, presenting factual in- (i.e., schizophrenia does not mean split
formation but balancing it with a good deal personality, most schizophrenics are not
of phenomenological examples of the ex- violent), a basic idea of the statistical occur-
perience of both the patient and the rela- rence of schizophrenia, and phenomeno-
tives. logical reports of patients who have been
Due to differences in terminology and through an experience ofthe illness.
emphasis, it was difficult to compile a sim- A major part of the discussion of diagno-
ple table which would convey the similari- sis is to demonstrate that the bizarre behav-
122 L. J. Cozolino and M. J. Goldstein
ior they have been experiencing is actually a The positive impact of such clear definitions
part of a "known" medical entity and that of the schizophrenic disorders can be seen
this experience is shared by many people in the following quotes from the relatives
throughout the world. Another goal is to re- cited in the preface of this volume whose re-
conceptualize the patient's deviant behav- actions to a psychoeducational program
ior as a reflection of his mental disorder were sought:
rather than as "bad" or "willful" behavior. I don't think the lay person knows very much
For example, in the syllabus of the Leff about what schizophrenia means, so it was a big
et al. family education program, it is stated educational, a big learning experience just to
that: learn what schizophrenia was.
· .. Schizophrenia is an illness. If affects people in
many ways. The difficulty is that the sort of ex- Symptoms
periences it gives rise to seem completely real to
the people suffering from it. For instance, some- A discussion of symptoms usually follows
one who hears voices may talk back to them be- diagnosis, which continues the process of
cause he thinks they are voices of people who are normalization. Perhaps for the first time,
actually there ... Because the patient cannot usu- relatives become aware that others have
ally explain what is happening in his mind, it is witnessed bizarre behavior such as their rel-
not always easy for other people, even those who ative has been exhibiting. The Falloon and
live with him like yourselves, to realize that many
the Liberman programs go through the var-
of the odd or upsetting things he does are caused
by the illness ... Schizophrenia is not a rare ill- ious symptoms, giving definitions and ex-
ness ... it can affect anyone. amples as seen below:

Besides attempting to "normalize" their ex- Falloon et al. (1980) Liberman et al. (1979)
perience to some degree, information Symptoms Symptoms
about diagnosis allows relatives to be better Disturbances of Thought broad-
thinking casting
able to communicate with professionals
Delusions Thought with-
they may encounter both in and outside of drawal
the program. Perhaps the biggest initial ob- Hallucinations Thought insertion
stacle in explaining the diagnosis of schizo- Incoherent talk Paranoid
phrenia is overcoming preconceptions delusions
based on movies and news reports and to Inappropriate Social with-
allay the fears of the patient and their fami- feelings drawal
lies based upon these misconceptions: Bizarre habits Work behavior
Self-care
· .. Schizophrenia means a disintegration of the Feelings
personality where a person finds it difficult decid- (flat affect)
ing what is real and what is not real. It is a little Thoughts
like having dreams when you are wide awake ... Conversation
We describe schizophrenia as a major mental ill- and speech
ness because it has a great effect on nearly every
aspect of a person's life. Everything that is im- While Leff and his group describe the above
portant in our lives may be affected by schizo- symptoms, their descriptions are less pa-
phrenia. The symptoms of schizophrenia are not tient centered and more focused on the in-
identical for every person, but they nearly always teraction between the patient and their rel-
produce a handicap in many aspects of everyday atives, as seen in the following excerpt:
living. (Taken from "What is Schizophrenia", Schizophrenia can also affect feelings .. . You
Falloon, McGill, and Boyd, 1980). may have noticed that he doesn't seem to care for
· .. a person suffering from schizophrenia has a you as he did before, or show his love for you in
different experience of reality than other people. the same way. There may be fewer and fewer
This means that the person with schizophrenia times when you can really talk to each other, and
sometimes relates to persons and events in a man- you may sometimes wonder whether he still feels
ner that is different enough from what most anything for you at all. He can't help this, be-
people usually expect that it can be said that the cause his usual feelings have been swamped by
schizophrenic has a split with reality. (Liberman the illness and he has become very wrapped up in
et al. 1979). himself.
Family Education as a Component of Treatment 123
Leff also describes: tions to the person with schizophrenia - is crucial
in the development and outcome of schizophre-
1. Instability of mood where the patient is at
times "miserable or desperate" and others nia.
when he is "very excitable and overactive" Thus, an important task of the information-
2. Social isolation al content is to shift focus from past fears
3. Reduced energy and blaming to a realistic and positive view
4. Apathy for the recovery process, involvement in the
5. Personal hygiene issues
program, and maintenance of the well-
Some of the programs go into an explora-
being of all family members.
tion of the phenomenology of a schizophre-
The problem of how to handle theories
nic psychosis. In the Hogarty/Anderson
concerning genetic factors is frequently ad-
survival skills workshop, excerpts of first-
dressed by developers of family education
person report of the inner experience of a
programs. The Liberman handout states,
psychotic break are read aloud and hand-
"Many people want to know if schizophre-
outs of such accounts are also provided to
nia comes from parents, they want to know
relatives. In the Falloon sessions, which are
carried out in the home with the patient pre- if they have to worry that someone else in
sent, both patient and relatives are asked to the family will get it. The heredity of schizo-
share their experience of the psychotic bre- phrenia is a complicated business, but it is
akdown. In both instances, it is reported clear that it sometimes runs in families and
that relatives report more sympathetic atti- sometimes does not." In other programs,
tudes toward the patient after such a session the genetic data are dealt with more expli-
as they appreciate that their relative's expe- citly. Any presentation of genetic theories
riences and behavior are not as unique as is likely to stimulate considerable discussion
they formerly believed. of risk factors for other offspring as well as
revive family arguments concerning whose
side of the family passed on the "bad"
Etiology and Course genes. Therefore, it is a topic that is covered
Although the etiology and course of schizo- in most family education programs but
phrenia may be the aspect of the illness needs to be handled with great care and sen-
which is least understood, it is perhaps the sitivity.
most important for the attitudes and morale Similarly, with regard to the stress side of
of the relative. Counteracting guilt con- the stress-diathesis theories covered in
cerning the cause of the illness and balanc- these programs, theories concerning the
ing realistic expectations for the future with family etiology of schizophrenia are either
a sense of hope is an important component played down or presented as unproven.
of these programs. All four programs are Stress, particularly during the post-dis-
grounded in a diathesis stress model of charge, aftercare period, is presented as a
schizophrenia, and they describe the genet- trigger of relapse, and family conflict is
ic as well as the environmental factors identified as a particularly potent stressor
which may contribute to the development during that period. Since a number of the
of schizophrenia. To the question "What is family education units are part of more ex-
the cause of schizophrenia?" Liberman et tended aftercare programs targeted spe-
al. explain: cifically for high EE family units, the im-
It is probably a better idea to think of the causes portance of reducing criticism and emotion-
of schizophrenia rather than a single cause. And al overinvolvement is emphasized as a
it is also important to think of factors which can mechanism for reducing family stress.
make the symptoms and life functioning better or While hope must be maintained, realistic
worse in a person who already has schizophrenia. expectations must also be supported. "Pre-
Since medication can improve the symptoms of paration" for relapse may serve as a stress
schizophrenia, it is likely that brain chemistry
changes are part of the problem. On the other inoculation as well as a sensitizer to a wor-
hand since psychotherapies and behavior thera- sening of symptomatology before another
pies which focus on the patient's environment episode.
also produce therapeutic change, it is felt that the In the Leff et al. syllabus, the following is
environment ... especially other people's reac- stated:
124 L. J. Cozolino and M. J. Goldstein
Some people only have one attack of schizophre- substitute with the dopamine and sneak-in there.
nia; they recover from this and never have anoth- The effect is to tone down the strength of the mes-
er. Others, luckily only a small number, do not sage, not as much can get through. This whole
respond to treatment at all. However, most pa- process of being excited and distracted and too
tients although they recover from the attack are much coming in at one time. This is a chemical
likely to have other attacks. These may occur way of enhancing the ... toning down process in
within weeks of recovery, or may happen years the cell which is not working at the moment. It
later. During further attacks new kinds of odd helps the body tone down and get equilibrium
behavior can appear, but often the same pattern back. It's the tune up - we're playing a trick on
will repeat itself. the receptors with medication. That's all we're
Although all of the family education pro- doing.
grams present material about etiology, they A key issue that is still unresolved is what
vary greatly in the detail covered. For ex- relatives and/or patients retain from the in-
ample in the handout Some Plain Facts formation provided. In some instances, lit-
about Schizophrenia, distributed by the tle of a technical nature is retained; in other
Liberman group as part of the family educa- cases, a key concept is retained which is
tion program, the section on causes of schi- found helpful. Consider the following
zophrenia states, "It is clear that schizo- quote from one of the relatives described in
phrenia involves a chemical problem in the the preface of this book who was sharing
brain. This is a problem that the person is her experience of family education:
born with and it's no one's fault." Contrast What helped was when you explained what hap-
this brief explanation with the extensive pens when there is a chemical imbalance or what
presentations by Hogarty, which covers is it, a dopamine flow? What happens inside their
some brief facts of neuroanatomy, neutro- head, I always had the idea that he could control
transmitter theory, the dopamine hypo- his symptoms, but we found that day that they
thesis, and the relationship ofthis model to really cannot control it. It is something that you
a hyperarousal theory of cognitive dysfunc- have no control over. It helped a greal deal, it
tion on schizophrenia. Hogarty states: really did, to know that he had no grip over real-
What you see on the board are two things that ity.
look like a star fish ... this is my feeble attempt to Or as another parent stated:
represent a neuron ... a neuron doesn't look that The number one point is that it is a chemical im-
big, in your brain right now there are the better balance like sugar diabetes that can be treated
part of ten billion neurons, and they are tightly with medication. He (the lecturer) went on to ex-
packed in ... I'm going to tell you a little bit about plain how this chemical imbalance bombarded
how the neuron works ... The center of the neu- with stimuli on the receiving end of the synapse
ron is the cell body and those little branches that made all kinds of sounds and sights magni-
which come out are ... called dendrites, and this fied - so the medication would screen out the
is a very important part ofthe cell body, the axon, dopamine that was bombarding your senses and
these are the nerve fibers ... There are messages eliminated some of the frightening sounds or sce-
that go through the body ... These ten billion nes or colors and they were brought down to nor-
neurons are connected but they are not physically mal perception and became more realistic.
wired together .. , and the message travels
through a very complex process ... Neuroanato- Even when retention is not great, relatives
mists refer to the message coming in as the af- often express appreciation that mental
ferent, they are affecting the cell and this would health professionals share with them the
be efferent ... (the spaces between cell) are cal- latest knowledge in this field. It is the be-
led synapses. After a description of dopamine ginning of an alliance, a building process
transmission, Prof. Hogarty continued: My guess than can facilitate relatives' investment in
is that everyone in this room has a family member the longer and more demanding phases of a
that has been ill who is receiving some form of sustained aftercare treatment program.
medication which we call antipsychotic medica- Difference in detail are also evident with
tion or antischizophrenic medication. You may regard to information provided about prog-
hear them referred to as tranquilizers. It turns out
that they don't tranquilize people, they operate nosis. Some programs are extremely ex-
on this (dopamine transmission) process ... They plicit in providing figures about relapse po-
put back the chemical balance. Those molecules tential while others are more vague One
look like the dopamine and they take its place, advantage of providing explicit figures
they block the crevice ... They'll compete and about relapse is that they provide a natural
Family Education as a Component of Treatment 125
segue into material concerning the protec- Maintenance drug
tive value of antipsychotic medication, a therapy
point emphasized in all four programs. Relapses rates and
medication
Symptoms likely
Treatment to improve
Symptoms likely not
All four educational components divide to improve
their treatment emphasis between pharma- Reasons patients
cological and psychosocial interventions re- stop taking
flecting the synthesis between these two medication
orientations, which until recently have Getting the right
dose
often been seen in opposition. The goal of Role of the family
this information is to increase drug com- in sustaining drug
pliance and stress the importance of both therapy
chemical and environmental components of
the illness.
Falloon et al. summarize their sessions on
medication thusly:
Medication 1. Regular tablet taking is the mainstay of
The Leff program describes medication: treatment of schizophrenia.
2. Major tranquilizers are very effective
These play an important part in the treatment of medicine for the treatment of schizo-
schizophrenia. They help to stop the voices in the
patient's head, they make him less anxious and phrenia.
restless and help him to think more clearly. They 3. In low doses they also protect a person
protect him against stresses coming from his own from a relapse of symptoms.
experiences and his everyday life. The effects 4. Side effects are usually mild and can be
cannot always be seen straight away. Some pa- coped with.
tients are not given tablets but are put on injec- 5. Street drugs make schizophrenia worse.
tions. These have the same effect as tablets but For the Liberman and Falloon projects, the
can be given less often. two sessions of education are followed by
interactive problem solving and communi-
In contrast to this minimal explanation of cation skills training, the actual details of
medication, the Falloon and Liberman pro- which are not described during education.
grams offer in-depth explanations of the The Leff and Anderson educational com-
range of medication and the benefits and ponents, however, include advice as to
risks of drugs used to combat side effects. what the families can do to assist the patient
The Leff et al. syllabus contains a single and themselves during the recovery pro-
page of drug information, while the Fal- cess. Their advice centers around reduction
loon, McGill, and Boyd syllabus is ten of contact, lowering EE, gaining support
pages long. Some of the psychopharmacol- from other families, and taking care of
ogical material provided by these investiga- yourself (the relative).
tors is summarized below. From the Leff et al. syllabus:
Falloon Liberman
Biochemical theory of Types of drugs The best thing for your to do in this situation is
schizophrenia Neuroleptics firstly, not to spend so much time with him so that
Types of medication Mood stabilizers you don't get on each other's nerves. It is impor-
Benefits of medication Antidepressants tant that the patient leads as independent a life
Reduced relapse Stimulants as possible ... If you have to be together a lot of
rates Types of neuroleptics the time, the best thing to do is not to shout or cri-
Relapse worse and effects ticize or get too involved.
without medication Generic names
Dosages Trade names The Anderson et al. psychosocial treatment
Warning signals Equivalent doses emphasizes both patient management and
Side effects Who is likely to concern for the relatives. The topics em-
Drugs/alcohol improve phasized are as follows:
126 L. J. Cozolino and M. J. Goldstein
Management ward understanding the experience of the
Benign indifference illness and contain information focused on
Realistic expectations
Normalization of family life
the long recovery period.
"Setting limits" The differences in detail offered and
manner of presentation may, in some cases,
Concern For Self be more an artifact of the authors presenta-
It may be a long process tion in their syllabi than of actual differ-
Take care of yourself ences in their programs. A great deal of
Mutual support between families flexibility is necessary to accomodate the
Families asked to share their wide range of needs and interests of the
gains with other families new to the project
various families of which these syllabi are
Written suggestions as to how to
start a parent's group are handed out as well merely a general format for presentation.
as information about parent of adult Thus, a program with a very detailed sylla-
schizophrenic (PAS) groups bus may omit detailed information to an
upset or low functioning family, while an-
With these foci, the Anderson et al. family other program with little technical informa-
education session remains true to its title of tion offers the opportunity for relatives with
survival skills workshop. a greater need for detailed information to
Throughout the educational component, have their questions answered.
each program maintains its basic perspec- It would seem that assessing the needs
tive. While they are all balanced with a mix- and abilities of the participants and match-
ture of didactic and experiential materials, ing information to these needs is crucial. In
the Falloon and Liberman programs take a program development, it may be best to
more information-oriented stance, which is have the ability and facilities to use these
separated from the rest of the treatment various modes of offering information
program. The Leff and Anderson programs about schizophrenia so that a wide range of
on the other hand seem more directed to- needs could and would be met.

Implications for Future Research on Family Education


Clearly, families need and desire informa- ation and thus increase compliance, (d) re-
tion and assistance. However, a number of duce family guilt concerning their role in
important issues concerning format, deliv- the cause of illness, (e) replace unrealistic
ery, and content require more research to expectations with more accurate estimates
optimize the impact of a family education of the length and nature of the recovery pe-
program. riod, and (f) give practical tips concerning
These programs described above, being management issues. While there are differ-
experimental in nature, incorporate many ences in the emphasis and focus of informa-
nonspecific factors, such as novelty and tion given to families during education, the
enthusiasm, which are difficult to quantify. basic theoretical positions are relatively
It is important, however, to compare pro- similar. Grounded in a diathesis-stress no-
grams in a way that provides information tion of etiology and theories of arousal and
about which components se.em most useful attention dysfunction, these programs have
and in which combinations. There are some a somewhat different emphasis from other
specific issues which call for discussion and educational programs based on orthomo-
investigation as program technology con- lecular hypothesis, for instance. Thus, in
tinues to evolve and expand. analyzing family reaction to this informa-
The programs outlined previously have a tion, it must be held in mind that their reac-
great many similarities, which is their most tions may be related to particular packages
striking feature upon first inspection. Their of information and not to information about
common goals are to (a) transmit informa- schizophrenia in general.
tion, (b) lead to a reduction of EE in the One salient aspect of family education is
home, (c) supply a rationale for the medic- the timing of the educational component in
Family Education as a Component of Treatment 127
the context of the long-term intervention. discussing issues concerning the mental ill-
Both the Berkowitz et al. and the Anderson ness of a relative. On the other hand, the
et al. programs have a phase prior to educa- group format may allow support and mutual
tion. While somewhat different in empha- sharing of feelings to develop across several
sis, they can serve to both assess the level of families and may reduce the pressure felt by
intellectual and emotional functioning of any single family. The general applicability
the relatives and to set the stage for the edu- of the group format becomes even more
cational component. In discerning the po- crucial when it is in the context of the ex-
tential position and negative effects of fam- tended treatment, as in the Berkowitz et al.
ily education, it may be important to ask program. The relative effectiveness of mul-
whether this preeducational connection tiple- vs single-family educational programs
should be considered optimal or whether it has yet to be assessed.
is for many a necessary prerequisite for a Whether family education takes place in
positive educational experience. Variations the home or at the treatment facility is an-
in the response to family education empha- other difference among these programs.
sizes the need for other tailoring informa- The added intimacy, increased information
tion in the educational component or for about natural family context, possible
doing remedial work with the family in pre- higher generalizability of treatment, and
paration for a structured group presenta- the lowered rate of missed sessions of home
tion. visits are balanced by the lower cost and
Another important issue of timing re- greater time efficiency for the professional
volves around at what point in the course of of having meetings in the hospital. Com-
the patient's illness should family interven- partive data on the effects of the location of
tion and education begin. The Anderson family education may yield information
et al. and Liberman and Snyder programs concerning the relative effectiveness of the
most often begin during hospitalization different venues as well as possible sugges-
while the Falloon et al. group waits from 4 tions about which families tend to benefit
to 8 weeks after patient discharge. The rela- most from which settings. Home visits may
tive merits of the different perspectives on prove to be especially important when
this issue of timing seems to be an important treating families of certain cultural and so-
point of discussion and further investiga- cioeconomic groups.
tion. The composition of the groups is also Patient reaction to family education has
relevant to the issue of flexibility in con- yet to be systematically assessed as well as
veying certain information. A group for- the differential effects of having the patient
mat, as used by Anderson, as opposed to involved or uninvolved with the family edu-
presentations to individual families, allows cation. Possible positive effects of patient
little adjustment to the individual needs of involvement, such as the added information
participants. The combined group/individ- obtained by the patient, the patient's ability
ual approach of Snyder and Liberman is an to give direct feedback to the family, and
interesting compromise allowing general avoidance of the patient's reactions to being
information dissemination followed by fo- "left out," may be counterbalanced by the
cused discussion. Responses from families relatives' needs to express their feelings and
in such programs will allow assessment of ask questions without the patient present.
the importance of presenting information Comparative patient feedback between the
specific to the ability level of the particular programs which include and exclude pa-
family members and specific to the particu- tients from family education should be eval-
lar ill relative. The usefulness of general in- uated and considered in future program de-
formation regarding the disorder presented velopment.
when the patient is first returning home can Consideration of informational content,
also be examined. Group presentation differences in intellectual level, level of
might inhibit relatives who are embarrassed stress, and the individual needs of the parti-
in a group or have difficulty in expressing cipants suggests investigation in the areas
themselves in front of strangers. This of: (a) the need for an impact of technical
inhibition may be especially salient when information, (b) the relative placement in
128 L. J. Cozolino and M. J. Goldstein
time and ordering in importance oftheoret- terpretations and reactions to various
ical and practical information, (c) the eval- pieces of data. Continued contact allows
uation of what is retained and what is for- more direct observation and assessment of
gotten and, (d) the possible negative side the impact and interpretation of the infor-
effects of information concerning medica- mation by family education.
tion, diagnosis, the extended recovery pe- While these research questions have
riod, and overall prognosis. Family reac- evolved in the context of long-term inter-
tions to information can be assessed in a vention programs for schizophrenic pa-
variety of ways in subsequent therapy ses- tients and their relatives, many of the same
sions, tests of information retention, and issues apply to any educational program of-
open-ended questions concerning their in- fered to relatives of a mentally ill person.

References
Anderson, C. M., Hogarty, G., and Reiss, D. J. and Moss, H. (1981). Family management
(1981). The psychoeducational family treat- training in the community care of schizophre-
ment of schizophrenia. In M. J. Goldstein nia. In M. J. Goldstein (Ed.), New develop-
(Ed.), New developments in interventions with ments in interventions with families of schizo-
families of schizophrenics (pp. 79-94). San phrenics (pp. 61-78). San Francisco: Jossey-
Francisco: Jossey-Bass. Bass.
Berkowitz, R., Kuipers, L., Eberlein-Fries, R., Goldstein, M. J. (Ed.) (1981). New develop-
and Leff, J. (1981). Lowering expressed emo- ments in interventions with families of schizo-
tion in relatives of schizophrenic. In M. J. phrenics. San Francisco: Jossey-Bass.
Goldstein (Ed.), New developments in inter- Liberman, R. P., Aitchison, R. A., and Falloon,
ventions with families of schizophrenics (pp. I. (1979). Family therapy in schizophrenia: Syl-
27-48). San Francisco: Jossey-Bass. labus for therapists. Unpublished Manuscript.
Falloon, I., McGill, c., and Boyd, J. (1980). Snyder, K., and Liberman, R. (1981). Family as-
Treatment of Schizophrenia - Part II: Medica- sesment and intervention with schizophrenics
tion. Unpublished Manuscript. at risk for relapse. In M. J. Goldstein (Ed.),
Falloon, I., McGill, c., and Boyd, J. (1980). New developments in interventions with famil-
What is schizophrenia? Unpublished Manu- ies of schizophrenics (pp. 49-60). San Fran-
script. cisco: Jossey-Bass.
Falloon, I., Boyd, J. L., McGill, C., Strang, J.,
11. Pilot Study of the Impact of a
Family Education Program on Relatives
of Recent-Onset Schizophrenic Patients
L. J. Cozolino and K. Nuechterlein

Introduction
It is assumed that advances in the technolo- ponent analyses may allow program coor-
gy of family education gained from broad dinators to direct available resources in
psychosocial research programs with schi- ways which will benefit the most clients.
zophrenic patients and their relatives (this However, there may be a tendency to enth-
volume, Chap 10, Goldstein, 1981) will be usiastically adopt family education, ab-
adapted and utilized in a variety of settings. stracting it from broader intervention pro-
Hospitals, professional training centers, grams, without understanding that the fam-
community mental health centers as well as ily's experience of education may be very
relative and patient support groups all de- different when such material is presented as
sire new and more impactful ways of de- a self-contained unit. Thus, as the technol-
livering information to their members. Spe- ogy of family education develops in the con-
cific analysis ofthe educational components text of broader intervention programs, par-
of these long-term treatment programs may allel research focused on family response to
be especially important for programs in education in the absence of family therapy
hospitals or community settings which can will increase our knowledge of the effects of
offer family education but may not have the family education programs in different the-
resources to conduct a full-scale family the- rapeutic or support contexts.
rapy program. In theory, educational com-

Pilot Study
As a first approach to this and more general sessions near the beginning of the outpa-
issues of family education, ten relatives tient program within 1-2 months of hospi-
from six different families with a schizo- tal discharge. Family members met with
phrenic member were interviewed. All rel- two UCLA Aftercare Clinic staff members,
atives participated in a family education usually on 3 consecutive weeks. They were
program in the context of an extended indi- given information about schizophrenia,
vidual patient aftercare treatment program. medication, and family stress management
All schizophrenic patients in this sample and discussed particular problem areas they
were enrolled in the Developmental Pro- were experiencing. The information given
cess in Schizophrenic Relapse Project (P. I. , to these families was adapted by Nuechter-
Keith Nuechterlein, Ph.D.) of the UCLA lein and Snyder from the programs of the
Clinical Research Center for the Study of earlier Liberman and Snyder (1981) project
Schizophrenia. The patients were all young, and the ongoing Anderson, Hogarty, and
recent-onset cases who were relatively early Reiss (1981) program. The information in-
in their contact with the mental health sys- cluded the sections on symptoms, possible
tem. The patients received medication and causal factors, and medication from the
individual and group therapy, while the Liberman and Snyder outline and those on
families were given three family education management of stress and communication
130 L. J. Cozolino and K. Nuechterlein
from the Anderson et al. outline. The fami- fects of stress, symptoms, the family role in
ly components of these programs were de- rehabilitation, family causes, medication,
liberately excluded because one focus of the and prognosis. If content was remembered
project was a medication-controlled exa- in each area, the usefulness and their reac-
mination of familial, behavioral, and psy- tion (i.e., if they found the information
chophysiological predictors of the course of comforting or disturbing) were discussed.
schizophrenic disorders and their predictive Ratings of usefulness of information
interrelationships. Thus, the family educa- were done on 8-point Likert scales where 1
tion program was purposely not an intensive was most useful and 8 was not useful at all.
attempt to change levels of expressed emo- Families were also asked to state what in-
tion (EE) or other familial factors and can formation they would have liked to have re-
serve as an example of the presentation of ceived which they were not given. Overall
family education without family therapy. program ratings were taken as well as rat-
These relatives were generally the same ings of specific management tips they re-
age and level of education as samples taken membered being told. Interviews were con-
by Hatfield (1981), and none were partic- ducted in the home because it was felt that
ipating in mutual support family groups in home interviews would afford families
the community. Thus, these people were more freedom of expression than the hospi-
generally isolated from others who shared tal environment. Families were assured of
their difficulties and, as a result of the ge- confidentiality and told that no feedback
ography of Los Angeles, most lived a good would be given to the clinic staff except
distance from UCLA. after it was combined with data from other
A semistructured consumer satisfaction families. The interviewer (L.J.C.) was in-
interview was conducted at their homes by troduced to the family by a telephone call
the senior author. The interview form is from the family's case manager and describ-
presented in Appendix A. While the format ed as an independent researcher who had
was somewhat structured, open-ended que- the support of the aftercare program but
stions allowed families a wide range of re- was in no way part of the treatment pro-
sponse. Relatives were first asked about the gram. This was done due to our concern
information they possessed prior to the ses- that they would feel that negative feedback
sions, where they obtained this informa- might jeopardize their relative's treatment.
tion, and how they reacted to it. Focusing The interview was conducted an average of
on the content of the program, they were 8.2 months after the last family education
then asked if they remembered specific con- session with a range from 5 months to 1
tent in the areas of diagnosis, cause, the ef- year.

Preliminary Results
General Reactions beginning the interviews, listening to step-
by-step detailed accounts of their relative's
While there were numerous suggestions for decompensation, their search for assist-
improvement, there was also consistent ance, or, more often, a description of some
praise for the program. Most felt that they current difficulty. Relatives also used us as
had finally found an ally after terrifying and a resource, asking for books, telephone
frustrating experiences with police, hospital numbers of family organizations, and refer-
staff members, and doctors. While the in- rals for therapists.
terview was fairly structured, relatives took Five of ten subjects remembered being
over for the most part and seemed to have a given practical tips, such as calling the
strong need to describe the details of their emergency number for assistance in a crisis,
family's difficulties. The interview had a reducing contact, and not pressuring the pa-
cathartic function for many as they vented tient. Of all the information remembered,
concerns and frustrations. We would often these tips were rated as the most useful. Of
have to wait between 15 and 30 min before the eight content areas, information con-
Pilot Study of the Impact of a Family Education Program 131
cerning medication was the most consist- I don't think it bothered us, we had already been
ently remembered and thought to be useful. bothered previously. (How?) When you go to the
hospital every day for a month and you see no
Relatives rated the data they were given change in your son - that bothers you ... so we
concerning cause and prognosis especially had already been bothered before. No it (the in-
unhelpful, describing it as too general and formation during the program) didn't bother us
vague. Especially in these areas, they felt at all.
that general information about schizophre-
nia was of little use as they went to the ses- On the other hand, some relatives who
sions expecting information specifically came expecting a rapid recovery period
about their ill relative. were distressed by the information that re-
It was found that the numerical ratings of covery would likely occur over a period of 1
relative usefulness had little meaning for year or 2. This raises an important issue
most of the categories beyond practical tips concerning the role of family education in
and medication because of the wide variab- fostering hope as well as instilling realistic
ility and the different mindsets with which expectations for the recovery process. A
the relatives were answering them (because delicate balance may need to be struck to
of this and in light of the small sample size at keep families actively and positively en-
the time of writing this report, statistical gaged in the treatment process. The impor-
evaluation has been omitted). Some rela- tance of maintaining this balance supports
tives took the stance that all of the informa- the notion of assessing the relative's expect-
tion was useful in contrast to total igno- ations prior to family education.
rance:
Anything is useful, you see, these questions are Did You Find the Information Pitched
really slanted from our context because - useful? at the Right Level for You?
Well God! Tell me anything - anything is useful.
I want to know! We have no backbone of infor- Another point of interest for us was wheth-
mation. er relatives found the information overly
technical, too elementary, or pitched at the
Others who really wanted extensive specific right level. None found it to be too techni-
information concerning their relative tend- cal, while those desiring more specific infor-
ed to rate all but the specific tips and infor- mation rated it as too elementary. While, in
mation on medication as too general to be general, relatives liked having the technical
useful: information about the possible role of neu-
We felt it was too general and a waste of time - it ral transmission abnormalities, "Its com-
got to the point where we didn't want to go back. forting to know that its something electri-
cal," their versions of what they were told
Was There Any Information Which You often caught us off guard:
Found Disturbing? Schizophrenia is like a tear in the brain - too
much chemical in the brain.
One goal of these interviews was to deter- There is a spot here (points to the center of the
mine whether any of the information dis- top of his head), she is missing this particular
turbed the family in any way. We thought thing and the medication can kind of work on that
that hearing the diagnosis of schizophrenia, area ... I can see that the medication has not
finding out about a prolonged recovery pe- made the gap any better.
riod, or hearing of the possible side effects And there are always the diehards even
of the medication might be particularly dis- after family education: "Schizophrenia is a
turbing during the family educational pro- split personality, isn't it?"
gram. In general, relatives reported that
they were so disturbed by their relative's
Did the Program Change the Way You Felt
behavior and the things they heard from po-
About Your Relative's Treatment?
lice and hospital staff prior to the educa-
tional program that they did not find the in- When asking relatives about the positive ef-
formation in the program to be particularly fects of family education, they found it diffi-
disturbing. One father stated: cult to separate the effects of the education
132 L. J. Cozolino and K. Nuechterlein
from the broader treatment program. Con- Would You Be Interested in Participating
cerning the sessions, one mother stated that in Relatives's Groups?
" ... they made me feel much more secure
None of these ten relatives were participat-
about the treatment. It also made me feel
ing in support groups, and only one expres-
that there was someone I could call." Thus,
the flesh and blood presence of a concerned sed even an interest in attending one ("but
professional seemed at least as important as only if it was close"). One said she was
the information. The information, while "anti-group" and another was quite upset
poorly remembered in many cases, repre- by the thought, saying:
sented a gesture of the establishing of a life- I don't want groups, I don't go for groups, I never
line, which was extremely positive. Rela- did go for groups, I don't want it ... I find that I'm
tives unanimously expressed their gratitude just not ready to go swap stories with other
and positive feelings toward the good inten- people. I don't feel that that is going to help me in
any way ... or just to know misery loves company
tions of the staff for offering their time. . .. NoWay!
None had ever been really given this sort of
attention before. A mother, when asked While previous research has addressed the
whether she found any of the information needs of members of relatives' groups,
comforting, keyed on the word comforting there is probably a still larger population of
and stated: relatives who have never participated in
Everything was a feeling of relief because we felt groups of any kind. It is interesting to con-
so isolated - once you get talking with other sider that the needs of these less social, less
people who deal with these problems and that interactive (if we can call them that) rela-
there was some place to tum for help - that's tives, may differ in significant ways from
what gave me relief - not so much the informa-
tion ... this program was a godsend.
those who will join groups and involve their
broader social network in the process of re-
Another mother was comforted by the fact covery. At the very least, it suggests that the
that other forms of treatment were explain- form of support and treatment that is view-
ed to her as well as the one offered by the ed as most desirables for families with schiz-
clinic. She said it made her feel as though ophrenic members may differ from one
she wasn't "up against an institution." population to the next.

General Issues Concerning Family Education


Certain issues appeared consistently confused and distanced by information
throughout the interview process which which was of "general" interest. One mo-
have specific ramifications for family edu- ther stated:
cation both inside and outside the context I don't remember the discussion very well at all.
of longer-term family treatment. At the time you're so involved with your own par-
ticular person's symptoms ... I don't think a
Information whole lot of things sink in that is general informa-
tion - at least it didn't for me. I knew what R.'s
Let's Get Specific! symptoms were.
It became clear to us during the course of Generally, relatives felt that it was difficult
the interviews that enthusiasm for impart- or impossible to translate general informa-
ing theoretical information to the relatives tion into specifically useful behaviors with-
of schizophrenic patients has some poten- out the help of the doctor. It seems that at
tial drawbacks which should be discussed. the beginning, their needs may be more
Schizophrenia was in no way a matter of specific to management issues and, as the
sheer intellectual curiosity to these families, pressures associated with severe symp-
they needed help, and they needed it fast. tomatology subside, perhaps a cognitive
They came expecting specific information understanding of the illness becomes more
about their relative and were somewhat important. The need for management ad-
Pilot Study of the Impact of a Family Education Program 133
vice relating to their relative seems most im- Format
portant. This need was sometimes not met
in the UCLA educational program because When Is Our Next Meeting?
the deliverers of the family education com-
ponent were not the patients' therapists and Besides wanting specific advice, relatives
were not necessarily deeply familiar with felt that follow-ups were essential. The in-
the individual case. Thus, they had only a formation and management advice appear-
limited amount of specific information that ed self-explanatory until they tried to im-
had been provided by the therapist. Famil- plement it at home. One father described
ies expressed a need for the doctors treating his experience:
their relative to be present at the sessions.
The illness of a family member does not You think, "That sounds easy ... I can do that"
occur in isolation of other problems and a but when it comes right down to it lots of times
you can't. We have the leaflet they gave us -
specific history. While specific skills are don't be sarcastic and all that stuff and that's fine
needed, they are interpreted and imple- ... it was useful ... but is wasn't very effective.
mented through the interpersonal and his- The things they said were the right things to do if
torical context of the family. One mother you could do them.
stated her confusion:
In four sessions one can't fill up a lifetime on what Parents expressed a need for the program to
had happened prior, so they go only by the time be given over a longer period of time for
that she had gotten ill. How do you separate that them to test out the management advice
part of your life from the area she's in now? ... they are given, to have an opportunity to
you can't and they did. see what sort of reactions the patient will
It seems difficult for relatives to separate have to medication, and to see how the re-
this part of their lives from their historical covery process will go. Specific difficulties
difficulties and conflicts. Without feedback, were consistently reported in the areas of
it is impossible to monitor how the informa- keeping a balance of discipline and freedom
tion is implemented and if it at all resembles for the patient especially when it involved
your intended results. keeping the level of emotion low. One
As part of their concern for the family, mother stated: "How do I keep it low-
parents are now vigilant for symptoms in keyed? I'm caught between fights (between
their other children and want specific infor- brothers). This is a natural conflict - I'm
mation concerning them: "They (the psy- fighting off fights." In giving general man-
chiatrists) asked about our son (the pa- agement advice without extensive follow-
tient's brother) and you start to worry about up, one risks establishing a failure experi-
him too. If it's hereditary ... what to say ence which may add to an already high level
that it won't." Besides specific information of guilt, frustration, and stress. One might
concerning the possibility of illness in their hypothesize that a management failure with
other children, parents requested informa- "expert" advice may add to feelings of pes-
tion concerning their children's interac- simism and hopelessness far outweighing
tions, especially competition. There were those which would occur in a trial-and-error
also instances of siblings concerned about approach by relatives. Relatives were sup-
their own health: "The psychiatrist said to portive of a program which would be less
my other son that there is a 30% chance that concentrated and spread out over a longer
this will happen to him." (This occurs de- period of time so that they could get advice
spite the presentation of accurate figures with their specific problems as they arose.
for risk of illness). One relative expressed this quite well when
Thus, there was much support for very she said:
specific information about an array of issues
Parent interviews should be spaced out rather
particular to a patient and the individual than all at the start cause you just don't know
family. Given the choice, these relatives what you need to know and need to remember
would have much preferred information when it happens at the beginning when you're
tailored to them, and most could have done upset anyway ... As things progress, they should
without general explanations. give you more as you need to know it.
134 L. J. Cozolino and K. Nuechterlein
Establishing Source Credibility aud loss as to which staff member to contact.
Coordiuatiou of Treatmeut These data seem to support Anderson
et al. 's use of a family ombudsman to co-
ordinate treatment, represent family con-
Who Is in Charge?
cerns to various staff members, and direct
The UCLA Aftercare Clinic program, like them to the appropriate professional for a
the other programs reviewed in this vol- particular difficulty.
ume, has a multidisciplinary staff. The re-
sult is that patients and their families come
Where Are They When You Need Them?
into contact with a variety of different kinds
of professionals, specifically psychiatrists, All relatives stressed the importance ofhav-
psychologists, social workers, and psychia- ing someone to call in emergencies, espe-
tric nurses. A greater understanding and ac- cially because things seem to go wrong late
ceptance of a medical illness model coupled at night and on holidays. Support in emer-
with the observable potency of pharmacol- gency situations was seen as one of the most
ogical interventions seemed to lead families important needs and most appreciated
to express a greater need to have interactive aspects of the Aftercare Clinic program,
feedback with the physician rather than which includes a 24-h emergency phone
with other staff members. This need is also number.
supported in that most individuals under- Relatives were unanimous concerning
stand the medical context and interventions the importance of feedback both to and
from personal experience while compara- from staff during the treatment process.
tively few have had psychotherapeutic con- Most wanted some form of regular informa-
tacts. One father stated: "Didn't under- tion concerning process in therapy and pro-
stand what the treatment was ... except for gnostic updates when possible. They also
medication. Everytime he came over here expressed a need for feedback during the
(this was the one family interviewed at the implementation of management advice
clinic) he was filling out some question- given to them during the family educational
naire, ... doing group therapy, ... I still program.
don't know what's going on." The notion of All relatives expressed a special need for
combining psychosocial and psychophar- feedback to and from the physician during
macological therapies seemed beyond their periods when the patient is adjusting to new
understanding (despite education empha- medication. They reported that the side ef-
sizing this combination), while the magical fects were quite disturbing, and there was a
presence and power of the physician was need for periodic reassurance as well as
held onto tenaciously. This perspective is feedback to the doctors concerning the pa-
clearly described by one mother: tient's symptoms.
They should set an appointment with the doctors
We were surprised to find that relatives
to talk to the parents even if it is for five or ten consistently mentioned that they did not
minutes - it would calm them considerably ... feel that the patient presented an accurate
otherwise you just don't know, you have all sorts picture of their "real" behavior to the doc-
of fantasies about what you think they are doing tors and wanted to have input in this way.
and even though there is a psychologist telling One mother was quite adamant that a short-
you, you don't trust those people like you do his coming of the program was that:
actual physician. Ten minutes with the doctor is
worth five hours with the psychologist - because ... more effort isn't made to get from the parents
you feel you are at the horse's mouth. what their opinions and observations are as to the
Instances were also noted when a specific patient's behavior. I don't think the patients are
honest with the doctors - they ought to check
problem of management was difficult to with the parents - the patient doesn't give an ob-
label as either psychological or medical. jective view of what his behavior is.
Relatives were often unsure whether a new
set of symptoms was related to medication This poses difficulty in the areas of parental
or a function of a "disturbed state of mind." overinvolvement as well as the maintenance
At these times, family members were at a of integrity and confidentiality of individual
Pilot Study of the Impact of a Family Education Program 135
patient treatment. Patient reaction to pa- logical and biological factors and the quali-
rental involvement in their therapy may tative differences between an illness such as
yield important information in this area as schizophrenia and most well-defined me-
well as a greater understanding of the rela- dical conditions.
tionship between overinvolvement and pa-
tient treatment. Another issue which family What Can I Believe?
education without subsequent family thera-
py might raise is the creation of positive ex- Most information in educational programs
pectancies for participation in the ongoing is presented as theory and expressed in ten-
treatment on the part of the parents. As a tative probabilities rather than delivered
result of their initial contacts, they may feel with certainty. The notable exceptions to
more isolated than if they were excluded this rule are the positive aspects of drugs
from the beginning. The UCLA program and the lack of evidence supporting a family
includes informal follow-ups by the individ- cause for schizophrenia. While this infor-
ual therapists. Perhaps initial family educa- mation appeared initially comforting to rel-
tion necessarily implies formal, scheduled atives, later some began to speculate: "If
follow-ups with parents to keep them sup- they are so unsure about all the other
portive of the therapeutic process. things, how can they be sure about this?"
Another trend among mothers was initial
relief upon hearing that they were not to
Who Can I Believe?
blame, followed by a return of guilt feelings
Family members in this sample described during the stress of the slow recovery peri-
the individuals who presented the educa- od. This growing doubt also took the form
tional materials as "nice social worker of fear concerning the long-term side effects
types", "well intentioned", "sweet", and as of the medications, which seemed to be
"really having their hearts in their work". fueled by the constant media barrage about
Most, however, said that they were expec- the delayed effects of all kinds of drugs,
ting an "authority" (i.e., physician) and pesticides, and chemicals. This data may
were thus somewhat skeptical about the point to a need for an evaluation of the
credibility of the information. Another fac- amount of certainty with which the infor-
tor to consider is that most of the informa- mation is presented as well as the need for
tion is presented as tentative theory (e.g., "booster shot" classes and follow-ups.
the dopamine model) rather than fact,
which is quite unlike the assertive confi- Assessing the Recipients of
dence with which their doctors have di- Family Education
agnosed and treated most of their illnesses.
Thus, it is easy to see how the lack of certain- Research has demonstrated differences in
ty in the presentation of information con- learning as a function of anxiety level, pro-
cerning issues of diagnosis, etiology, and longed stress, prior learning, and expecta-
prognosis could result in negative attribu- tions. Recipients of family education are af-
tions concerning the expertise of the in- fected by all of these factors. They are re-
structor rather than appreciation for the ceiving information about an emotionally
comparative complexity of schizophrenia charged issue which has caused them a great
and the actual state of knowledge relative to deal of personal distress; they are also
most commonly treated medical difficul- asked to make specific changes in their
ties. behavior. Thus, benefiting from family ed-
This feedback suggests that an initial ap- ucation not only involves one's cognitive
pearance by the physician could be impor- skills and affective state but also personal
tant in decentralizing power and describing history and interpersonal and communica-
the roles and expertise of the various tion skills.
professionals. The task at the outset may be Most relatives enter family education
to redirect a lifetime of thinking of illness with a great deal of misinformation, with a
from a medical perspective to an under- high level of stress, and uneasy as to what
standing of the interaction between psycho- will happen next. They also have a wide
136 L. J. Cozolino and K. Nuechterlein
variety of expectations concerning the ses- we are causing them to recall their involve-
sions and what will take place. The great ment in the program. These individuals see-
variability in this group of relatives led us to med to want to carry on life as usual and
speculate that there may be information were most pleased with the program as an
about some specific aspect of family func- auxilary caretaker: "It was good just to have
tioning which could suggest variations that someone to tum your troubles over to."
could optimize information presentation These individuals also seemed to remember
and format, if assessed prior to the pro- least about the program, even though they
gram. Five areas which stand out from the were interviewed within a shorter amount
interview materials are coping style, previ- of time since receiving family education
ous information, level of anxiety, attitudes than other relatives who remembered much
toward treatment, and need for a balance of more. If this is a reliable phenomenon, it
hope and realism. may offer some clues about how to tailor
family education and treatment to address
this issue. A full complement of references
Coping Style
and detailed information may be made
In our experience with this small group of available for copers while avoiders may
relatives, we found that different coping need clear, step-by-step instructions for
styles seem to be operating with respect to emergencies that they can take home and
information and involvement in the recov- use when needed.
ery process. A coper/avoider phenomenon
(Goldstein, 1973) seemed to be present in
Previous Information
many family members that is similar to the
integrator/sealing over distinction noted Everyone had their horror story concerning
among recovering schizophrenic patients what they had been told by doctors about
(McGlashan, Levy, and Carpenter, 1975). their relative's illness before becoming part
For some, the need to know and be involved of the Aftercare Clinic program. For ex-
was very strong, which led them to ask nu- ample:
merous questions during family education Doctor: Your daughter is a psychotic schizo-
and continue the process by reading and tal- phrenic.
king to others. They seemed to gain some Mother: Does that mean my daughter is insane?
sense of control or mastery over the process Doctor: Yes.
by wanting to know as much as possible. Father: At that point she (the mother) became a
This feeling was expressed by four of ten of basketcase.
the relatives in statements such as: After 5 days in the hospital, all of A ... 's doctors
Ignorance is frightening - the more you know, got together and came to the conclusion that he
the more you feel secure. was schizophrenic. They felt that he was an in-
I'd like to know, that's what I'd like to do. I'd curable schizophrenic ... then I got mad.
really like to know, I'd like to know what the pos- Beside these experiences specific to their
sibilities are, what we can do, anything that we relative, some other connotations of the
can help with, whatever, I want my daughter to word "schizophrenic" were not shared. In
be a well girl.
interviewing one husband and wife, we
These individuals were the most impressed asked if the fact that the recovery process
with information concerning biochemical would be a couple of years was disturbing to
theory and the action of the medication. them. The husband said "yes" because he
The more precise or scientific the better. had heard from someone that it would be a
These were often the individuals who also matter of months; the wife, who had taken
wanted the most specific information con- a psychology course 20 or so years ago, sta-
cerning their involvement in the treatment ted that that made her quite happy because
process: "I wish they could have said to me she had remembered it to be a totally in-
you're doing this wrong, you're doing that curable illness. This example underscores
wrong and this is what you should do." the discrepancies between family members'
Others seemed nearly indifferent to the prior knowledge and the importance of
information and somewhat annoyed that establishing an information base line prior
Pilot Study of the Impact of a Family Education Program 137
to the family educational process. This may helpful in understanding and supporting the
facilitate the goals of reeducating and pro- patient through the treatment process.
viding comfort to these families.
Balancing Hope and Realism
Level of Stress One of the expressed purposes of family ed-
ucation is to reduce pressure on the patient
It is clear that families are under a great deal by revamping relatives' unrealistic expect-
of stress during or immediately after the ations for a quick recovery. Relatives are
time of their relative's hospitalization, often anxious for the patient to get back to
which is when most family educational pro- work or school and to just be "normal"
grams (in the context of long-term treat- again. In most programs, the recovery peri-
ment) are given. While this has been re- od is described as at least a 1- to 2-year pro-
peated numerous times by many profes- cess with possible severe setbacks without
sionals, it was especially meaningful to hear proper adherence to the medication sched-
it expressed by relatives. When we asked ule. While this is important, there seems to
one mother about the most important be an element of danger in being too realis-
points in the program, she described a need tic with relatives right from the beginning.
to state the information slowly, clearly, and One mother expressed her distress by stat-
repeatedly. She dramatized the process of ing:
giving the relative the clinic number by tak- I would have liked more positive than negative
ing a card and pressing it firmly against her hope. The whole picture they presented was so
palm, saying: "Make sure people have the bleak - they didn't give me much hope. I think
clinic number - it's like talking to a child that when you're talking to a parent at that time,
because parents are very distraught." to sit and tell the parent that it's at least 3 years.
If he stops the medication, he may regress a
Perhaps, at least initially, our goals in
whole year and never come back. If I wasn't so
transmitting information should be quite positive I would have said, that's it - I have an
modest and subordinate to the needs of rel- idiot son for the rest of my life.
atives to build a bond of trust with the staff.
Assessing the amount of trauma or shock a While all relatives interviewed stressed the
relative is experiencing may give important need to be told the truth concerning the ill-
direction about how to proceed in the be- ness, most stressed the importance of en-
ginning stages of the program. This might couragement during the initial phases of the
take on the role of venting, dealing with treatment process. While they found the
personal issues of the relatives, or just shar- existence of the program reassuring, they
ing coffee. During the interviewing expe- found the realities of the extended recovery
rience, we found that relatives had a very period unsettling. Families enter education
high amount of emotion still locked into with a spectrum of expectations concerning
these issues 5 months to 1 year later. schizophrenia drawing parallels to every-
thing from a fever delirium to an incurable
Attitudes Toward Treatment brain disease. Assessment ofthese assump-
tions, expectations, and their level of
It may prove helpful to assess initially the distress prior to education may give facilita-
relative's attitudes toward the treatment tors more insight into how to balance hope
process and their general perspective to- with realistic expectations for a particular
ward medication, hospitals, and therapy to family. Some balance which would relieve
see if any remedial education or public rela- pressure from the patient but would also
tions work needs to be done. Some family encourage the relatives would be optimal.
members called themselves "anti-psychia-
try" while others seemed to have an almost
religious commitment to medication and
the medical model. Few had experience
with verbal psychotherapies, and some edu-
cation in this area may have been quite
138 L. J. Cozolino and K. Nuechterlein
Summary
Preliminary evaluation of these initial fami- into specific behaviors at home. There
ly interviews suggests specific and nonspe- appears to be a possibility of discourage-
cific effects of family education and raises ment and an increase in feelings of pessi-
many possibilities for investigating the rela- mism and guilt when advice is unsuccessful-
tive effectiveness of various approaches. ly implemented. Parents reported concern
This feedback from relatives present sug- about the possibility of their other children
gestions for education in a broader treat- becoming ill and requested more informa-
ment context, as well as pointing to possible tion in this area. Further research may sug-
drawbacks in presenting family education gest that especially in education programs
without adequate follow-up. without familiy therapy, equipping rela-
For the most part, relatives interviewed tives with survival skills should have priori-
thus far have found most of the theoretical ty over and precede the presentation of
information interesting but too general to general information.
be of much practical use. The exception to The consensus regarding format was that
this was information concerning the med- the need for follow-up and feedback is es-
ication and its side effects. Relatives seem- sential especially in the implementation of
ed to be most appreciative of practical management advice. Relatives suggested
management advice at least during the giving the information slowly, repeatedly,
initial phase of the patient's reintegration and simply, especially at first. The more
into the home and community. The sessions spread out the sessions, the better the op-
seemed to have the overall positive effect of portunity to implement and monitor the ef-
creating the feeling of a lifeline between fects of specific management tips and then
families and the treatment program. Rela- receive feedback. They also reported
tives reported a greater support for keeping changes in symptomatology over the course
their relative on medication as a result of of treatment and the need for updated ad-
the sessions. They were not disturbed by vice as new difficulties arose. Thus, given
the information except where the news of a limited resources, relatives seemed to sug-
1- to 2-year recovery period was introduced gest a slow pace with long intervals, as op-
to relatives who expected a rapid recovery. posed to a concentrated program when the
They found the information pitched at the patient is first released. From this perspec-
proper level and were particularly impres- tive, family education in the absence of on-
sed by biochemical explanations of neural gong support would not be of adequate as-
transmission and the effects of medication. sistance. A free-standing educational pro-
Only one of ten relatives thus far have been gram lacks the all important ability to give
willing to participate in family support ongoing feedback concerning practical ad-
groups. This points to the existence of a vice and lacks a way to monitor how the in-
large population of relatives of the mentally formation is interpreted and utilized. Be-
ill who are not participating in relatives' yond this, there may be the risk of creating
groups and thus may not be represented in positive expectancies of long-term assist-
research of family needs (Hatfield, 1979, ance with initial family education, which
1981). Research with these populations may lead families to be more discouraged
may suggest some important differences in with the passage of time. This is speculation
the uses of social support and the willing- on our parts and needs to be assessed.
ness to participate in group treatment. Many changes in the conceptualization
In the area of information, relatives stres- and treatment of schizophrenia have result-
sed the priority of specific management ad- ed in confusion for relatives. Information
vice over theoretical information. At least they have from the past and that which they
initially, survival skills superceded curiosity are now receiving is often vastly contradict-
in their minds. The more concrete and pa- ory. Add to this the mUltidisciplinary staf-
tient specific the information, the more use- fing of therapy programs, the strength of
ful it was found to be. Relatives reported the medical illness model in their minds,
great difficulty in translating general advice and the potency of the pharmacological in-
Pilot Study of the Impact of a Family Education Program 139
terventions and you have relatives straining nesses of students is done in most educa-
to get to speak to the physician for some tional settings. What we are asking of rela-
"truth". This is accentuated by the fact that tives is far more than remembering infor-
most of the information is presented as mation in a usual classroom sense. We are
theory instead of fact. Thus, establishing requesting specific changes in lifetime
source credibility and coordination of treat- behavior patterns in the context of an ex-
ment stands out as a major obstacle to the tremely stressful experience with a handful
family's understanding and integration into of tentatively held theories. In light of this,
the treatment process. For families to gain it seems that tailoring the information and
the full benefit available from individuals manner of presentation to account for what
with various expertise, it may be that edu- relatives are capable of understanding and
cation about the treatment program and the effectively using at the time may be a fruit-
decentralization of power should be one of ful area of future research.
the first orders of business. In line with this, While many factors have led to the de-
the question of who should present infor- velopment of family education and therapy
mation becomes an important area of in- in the treatment of schizophrenia, the nega-
vestigation. tive effects of emotional distress and ten-
In interacting with these families, the sion on patient recovery have been among
wide variability of anxiety levels, expecta- the most important. As researchers focus-
tions, and prior learning seemed to be the ing on schizophrenia, we measure program
most salient factors in determining their re- success as a function of lowered relapse
action to family education. The possibility rates or symptomatic relief of the patient.
of assessing the recipients of family educa- The well-being of the family is usually ap-
tion to maximize utility and learning could proached only from the perspective of its
be a possible area of investigation as pro- positive or negative effects on the identified
gram technology develops. Differences in patient. It is clear that for most families, a
coping style, previous information, level of psychotic break in one of their members is a
stress, and attitudes toward treatment, if as- major life stressor. The amount of stress
sessed, may allow a tailoring of information and disruption may vary from the aunt who
to best fit the needs of a particular relative lives in the next town to the husband who is
or family. Another important variable the primary supporter of the family. Be-
seems to be a proper balance of hope and sides the great interpersonal strain, a rela-
realism as relatives brace themselves for the tive's breakdown may result in major
recovery process. This may be the most im- changes, such as the modification and/or
portant role of family education and the dismissal of long-term plans and goals, ad-
best reason to properly assess the relative's ded economic burdens or total loss of in-
expectations and attributions prior to giving come, marital pressures, separation or
them information. Broader interventions divorce, decreasing outside contact and
which have contact with relatives prior to possible isolation, and a consistently stress-
family education are able to assess the psy- ful home environment. Thus, the families
chological state, intellectual capacity, and as well as the patients seem to be "at risk"
other important factors which allow tailor- for emotional difficulties. As educational
ing of presentations to match the recipients. and therapeutic interventions expand to in-
Group programs do not allow this flexibi- clude the family, it may be that the meas-
lity, but broader intervention programs urement of program utility and success
have the opportunity to clear up misunder- should also expand to include the coping
standings and deal directly with family re- and well-being of other family members.
actions. Group programs which stand on Perhaps by focusing only on the patient we
their own have no means of assessment and are missing the other half of the value and
no opportunity to make adjustments overall cost effectiveness of family inter-
without follow-ups. ventions as a primary prevention strategy
The notion of choosing the content and for physical and psychological illness for
format based on the strengths and weak- relatives.
140 L. J. Cozolino and K. Nuechterlein
References
Anderson, C. M., Hogarty, G., and Reiss, D. J. Hatfield, A. B. (1981). Coping effectiveness in
(1981). The psychoeducational family treat- families of the mentally ill: An exploratory
ment of schizophrenia. In M. J. Goldstein study. Journal of Psychiatric Treatment and
(Ed.), New developments in interventions with Evaluation, 3,11-19.
families of schizophrenics. San Francisco: Jos- McGlashan, T. T., Levy, S. T., and Carpenter,
sey-Bass. W. T. (1975). Integration and sealing over.
Goldstein, M. J. (1973). Individual differences in Archives of General Psychiatry, 32,
responses to stress. American Journal of Com- 1269-1272.
munityPsychology,1 (2),113-117. Snyder, K., and Liberman, R. (1981). Family
Goldstein, M. J. (1981). New developments in assessment and intervention with schizophre-
interventions with families of schizophrenics. nics at risk for relapse. In M. J. Goldstein
San Francisco: Josey-Bass. (Ed.), New developments in interventions with
Hatfield, A. B. (1979). The family as partner in families of schizophrenics, San Francisco: Jos-
the treatment of mental illness. Hospital and sey-Bass, p. 49-60.
Community Psychiatry, 30, 338-340.
Appendix A

Family Interview
Do you recall the session(s) at UCLA (or at your forting or' reassuring?
home) in which you were given information 10. Why do you feel that it was comforting or
about the causes and treatment of your relative's reassuring to you?
mental illness?
I would like to ask you some questions con-
cerning your experiences during these sessions. UCLA Sessions/General Impressions
This is not a test in any way! It is a consumer sur- 11. Generally, what do you recall being told
vey designed to find out whether or not these ses- about the nature of your relative's disorder
sions served your needs. All of this information is during the family education sessions?
confidential and will not be shared with clinic 12. Overall, did you find this information useful?
staff except after it is combined with responses Yes No
from others who have participated in the pro- 1..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
gram.
13. What information stands out in your mind as
Previous Knowledge being particularly useful in some fashion?
14. What kinds of information stand out in your
1. Before we discuss the sessions, I would like mind as not so useful?
to get an idea of how much you had learned 15. Overall, did the information you were given
about your relative's illness before you par- during the sessions seem to agree with your
ticipated in this program. How would you experience with your relative?
rate the amount of information you had Completely In large part About half
prior to these sessions? Somewhat Not at all
A Great Deal Nothing
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 16. In what ways did it seem to agree?
17. In what ways did it disagree?
2. What prior information did you find useful? 18. Overall, did the information tend to agree
3. What prior information did you find not so with the information you knew or believed
useful? prior to the sessions?
4. Where did you obtain this information? Completely In large part About half
Previous doctors _ _ Somewhat Not at all
Books _ _
Friends _ _ 19. What stands out in your mind in this regard?
Others __________________________ 20. Were any of the things you were told disturb-
5. Was any of the information you received be- ing to you?
fore you participated in the session(s) dis- 21. (If yes), what were they and how were they
turbing to you? disturbing?
6. (If yes), what information did you find dis- 22. Overall, do you feel the information was pit-
turbing? ched at the right level for you?
7. Why do you feel that it was disturbing to Too elementary Right Too technical
you? 1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
8. Was any of the information you received be-
fore you participated in the session(s) com- 23. What stands out in your mind as being too
forting or reassuring to you? elementary?
9. (If yes), what information did you find com- 24. What do you remember as being too tech-
142 Appendix A
nical? ing the causes of mental illness comforting or
25. What things do you remember that seemed reassuring?
just right? 46. (If yes), what did you find comforting and
26. As a result of the program do you feel that reassuring and why?
you have a greater or lesser understanding of 47. What weren't you told about the causes of
your relative's illness? mental illness that you would have liked to
Greater understanding Lesser understanding have been told?
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8

27. Overall, what weren't you told about that Effects of Stress
you would have liked to have known?
48. Do you recall being told anything about the
effects that stress may have on mental ill-
Diagnosis ness?
28. Many sessions include a discussion of diagno- 49. What stands out in your mind in this regard?
sis, you know, words like schizophrenia, 50. How useful have you found this information
schizophreniform, psychotic reactions, or to be?
other mental disorders. Do you recall di- Useful Not useful
agnosis being discussed during your ses- 1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
sion(s)?
29. What stands out in your mind in this regard? 51. What information did you find most useful?
30. Do you find that this information is useful to 52. What information did you find to be not so
you? useful?
Useful Not useful 53. Did you find any of the information comfort-
1 ..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 ing or reassuring?
54. (If yes), how was it comforting and reassur-
31. In what ways do you find this information ing and why do you think that it had this ef-
useful? fect?
32. Are there ways in which you feel it is not use- 55. Did you find any of this information disturb-
ful? ing?
33. Was there anything in the discussion of di- 56. (If yes), how was it disturbing and why do
agnosis which you found comforting or re- you think that it was disturbing to you?
assuring? 57. What weren't you told about the effects of
34. (If yes), what did you find comforting or re- stress that you would have liked to have
assuring and why? known?
35. Was there anything in the discussion of di-
agnosis which you found disturbing?
36. (If yes), what did you find disturbing and
Symptoms
why?
37. Was there anything about diagnosis that you 58. Do you recall during the sessions discussing
would have liked to have been told that the various symptoms your relative may be
wasn't included in the sessions? experiencing?
59. What stands out in your mind in this regard?
Etiology 60. Did you find the information useful?
Useful Not useful
38. Often, the cause of mental illness are dis- 1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
cussed in these sessions, do you recall this
being discussed? 61. What did you find to be most useful?
39. What stands out in your mind in this regard? 62. What information was least useful?
40. Did you find this information useful? 63. Was any of the information concerning
Useful Not useful symptoms disturbing to you?
1 ..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 64. (If yes), what did you find disturbing and
why?
41. What information did you find most useful? 65. Was any of the information concerning
42. What information did you find least useful? symptoms comforting or reassuring to you?
43. Did you find any of the information concern- 66. (If yes), what did you find comforting and
ing the causes of mental illness disturbing? reassuring and why?
44. (If yes) , what did you find disturbing and why 67. Are there things which weren't discussed
do you feel it disturbed you? that you would have liked to know more
45. Did you find any of the information concern- about?
Appendix A 143
Family Role in Rehabilitation 89. Did you find this information useful?
Useful Not useful
68. Many sessions include advice to relatives as
1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
to how they can best help the patient during
the recovery process. Did your sessions con-
90. What do you recall as being useful?
tain any information in this area?
91. What do you recall as being not so useful?
69. What stands out in your mind in this area?
92. Do you recall being told about the possible
70. Have you found this information to be use-
side effects of the medication?
ful?
93. Did knowing about the possible side effects
Useful Not useful
help you keep your relative on medication?
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
94. Was there anything discussed concerning
medication which was disturbing to you?
71. What do you recall as being most useful?
95. (If yes), what did you find disturbing and why
72. What information seems to be least useful?
do you feel that it disturbed you?
73. Was any of this information comforting or
96. Was there anything discussed concerning
reassuring to you?
medication which was comforting or reas-
74. (If yes), what did you find comforting or re-
suring to you?
assuring and why do you feel that it had this
97. (If yes), what did you find comforting or re-
effect on you?
assuring and why do you feel that it was reas-
75. Was any of the information disturbing to
suring to you?
you? 98. What weren't you told about medication that
76. (If yes), what was disturbing and why do you
you would have liked to have known?
feel that it was disturbing to you?
77. Are there issues concerning the family's role
in rehabilitation that you would have liked to Prognosis/Recovery Period
discuss that were overlooked during the ses-
99. One session may have included advice con-
sions? cerning your relative's convalescence or
recovery period. What do you remember in
Family Etiology this regard?
100. Was this information useful?
78. Many times when a family member is stric- Useful Not useful
ken with a psychological illness, close relati- 1 ..... 2 ..... 3 ..... 4 ..... 5 ..... 6 ..... 7 ..... 8
ves may feel that they are in some way to
blame or that there may have been some- 101. Was this information comforting or reas-
thing that they could have done to prevent suring in any way?
the illness. Did you experience any of these 102. (If yes), what did you find comforting and
feelings when your relative became ill? reassuring and why?
79. What kinds of feelings did you have in this 103. How did you react to this information, was
regard? it disturbing to you in any way?
80. Was this discussed in the sessions at all? 104. (If yes), what did you find disturbing and
81. Was anything said that was disturbing to why?
you? 105. Was there any discussion concerning your
82. (If yes), what was disturbing to you and why? relative's future?
83. Was anything said that was reassuring or 106. What do you recall being discussed?
comforting to you? 107. How did you react to this information, was
84. (If yes), what was comforting and why do feel it disturbing to you in any way?
it was comforting to you? 108. (If yes), what did you find disturbing and
85. What do you remember being said about why?
these issues? 109. How useful did you find information con-
86. As a result of your attending the sessions, cerning your relative's future?
have your thoughts and/or feelings changed Useful Not useful
in regard to this issue? 1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8

Medication 110. Were there areas of discussion concerning


the future that you would have liked to
87. The role of medication in the treatment pro- cover that were not discussed?
cess is often a topic of discussion. Do you re-
call medication being discussed?
Practical Tips (Survival Skills)
88. What sorts of information stand out in your
mind in this regard? 111. Often the sessions include practical tips in
144 Appendix A
day-to-day living with the patient. Do you 117. In what way?
remember any of these tips? 118. Did participation in the educational pro-
112. Which ones stand out in your mind? gram affect the way you feel about your rel-
113. Please rate each tip after description ative's treatment?
Useful Not useful 119. In what way?
1. .... 2 ..... 3.... .4 ..... 5 ..... 6..... 7 ..... 8

114. What things have you learned about how to Other Participants
deal with your relative's illness which might 120. Were there members from other families
be useful to other families? with you when you went through the pro-
115. Were there practical sorts of advice that you gram?
weren't given that you would have liked to 121. How many others were there?
have gotten?

Relating to Doctors, Clinic Staff,


Other Professionals, etc.
116. Did participation in the educational pro-
gram affect the way you feel about the after-
care clinic program or staff?
12. Psycho educational Family Therapy
C. M. Anderson

Introduction
In recent years, several models of family dropping out after only a few visits. It has
treatment have been developed which at- become important, therefore, to develop
tempt to include an educational component treatment programs which would help fam-
as part of a larger program of intervention ilies to perform this caretaking role, pro-
for schizophrenic patients and their famil- grams which are not dependent solely upon
ies. These models can be generally classi- the motivation of patients.
fied as psychoeducational family therapies. Second, recent British studies of expres-
They aim to keep patients out of hospitals sed emotion (EE) have confirmed long held
and return them to productive life in the clinical impressions that families have an
community by teaching patients and famil- impact on the course of the patients' illness.
ies about the illness and its management, These studies demonstrate that measures of
treating the family as a resource rather than high EE in family members is correlated
as a stress, focusing on concrete problem with high relapse rates for patients. (Brown
solving and specific helping behaviors for and Birley, 1968; Brown, Birley, and Wing
coping with stress, and working in tandem 1972; Vaughn and Leff, 1976; Hooley,
with medication programs. These models Chap. 2). These findings have stimulated
emphasize the likelihood of a biological increased interest in attempting to develop
basis of the illness and the negative impact ways of modifying family systems to de-
of stress on patient ability to function. The crease family intensity and thus the likeli-
underlying assumption of the interventions hood of patient relapse.
used in psychoeducational models is that Third, the first controlled study which in-
giving families information about the na- cluded an attempt to provide patients and
ture of the illness, along with specific sug- families with some understanding of the ill-
gestions for coping with it effectively, can ness and ways to cope with had dramatic re-
decrease tIie intensity and conflict inherent sults. Michael Goldstein and his colleagues
in family life, and thus decrease the likeli- from UCLA (Goldstein, Rodnick, Evans,
hood that patients will relapse. May, and Steinberg, 1978) designed a 6-
There seem to be a number of reasons week program of family therapy in which,
why these models are attracting so much following hospitalization, patients were
attention today. First, major changes have randomly assigned within a 2x2 design:
occurred in patterns of mental health care high- or low-dose drug therapy, and family
for severely disturbed patients. Policies therapy or no therapy. The Goldstein
supporting deinstitutionalization have cau- model of family intervention was brief, con-
sed minimally functioning patients to be re- crete, and problem focused. The goals of
turned to the community after very brief the program were to identify the events that
hospitalizations. Consequently, families were stressful to the patient and then to pre-
have become long-term primary care agents vent the occurrence of these events or to
for very disturbed patients. Many of these mitigate their destructive impact. Family
patients do not cooperate with plans for af- sessions began by exploring the psychotic
tercare treatment, failing to attend at all or experience, with the therapist helping the
146 C. M. Anderson
patient and the family to discuss the illness family therapy and high doses of medica-
and its symptoms. Out of these discussions, tion. In other words, this intervention pro-
the therapist helped the family and patient gram achieved its primary goal of helping
to identify and agree on two to three specif- patients to maintain themselves in the com-
ic stresses that were of particular current munity during the high-risk period immedi-
concern. Conflicts with significant others or ately following hospitalization through the
other stresses, that are viewed as potential- provision of only six sessions of family ther-
ly precipitating a psychosis were emphasiz- apy. Although the differences between the
ed. Although symptoms themselves were groups were less dramatic at long-term fol-
often labeled as stressors, attempts were low-up points (Goldstein and Kopeikin,
made to focus on the interpersonal conse- 1981), the impact of this program was dra-
quences of symptoms rather than symptoms matic enough to inspire increased optimism
perse. regarding attempts to intervene with fami-
Following the identification of stressors, lies of schizophrenic patients.
the therapist helped families to develop This paper will describe the psychoedu-
strategies to avoid these stresses or methods cational model developed in Pittsburg as a
of coping with them when they occurred. part of a larger research project, which is
With the therapists guidance, the need for both attempting to replicate the British
both the family and the patient to accomo- work on EE and attempting to investigate
date to the other was emphasized. Once the impact of various strategies of interven-
coping strategies were developed, the ther- tion in the aftercare of patients with schizo-
apist helped the patient and the family to phrenia.! The larger research project
implement them. When necessary, coping screens patients to insure they meet Re-
skills were developed using direct teaching, search Diagnostic Criteria for schiz-
coaching, and practice. When problems ophrenia, rates the level of EE of their
arose in the implementation of these new family members, and randomly assigns
coping strategies, obstacles to the imple- patients with high EE families to one of four
mentation process were analyzed and the treatment cells: family therapy, social skills
strategies were modified. Finally, thera- training, family therapy and social skills
pists helped families and patients to antici- training, or medication alone. Patients and
pate and plan how they would handle future their families are followed in these treat-
stress. ment modalities for 2 years with various
The results of this short-term program measures of individual and family function-
were extremely positive. After 6 weeks of ing taken at periodic intervals. This paper
treatment, the low medication-no family will briefly note the assumptions and goals
therapy group had a relapse rate of 24% of the family program, describe its compo-
while the high medication-family therapy nents and stages, present some preliminary
group had no relapses at all. After 6 findings about its effectiveness alone and in
months, the relapse rate increased to 48% combination with social skills training, and
for the low dose-no family therapy group, discuss some of the common elements of
but remained at 0% or those receiving this and four similar programs.

Assumptions
It is assumed that whatever the "cause" of Tecce and Cole, 1976; Venables, 1964,
schizophrenia, patients with schizophrenia 1978). This patient vulnerability is probably
appear to have a "core psychological defi- exacerbated by the range of behaviors and
cit," which appears to increase their vul- emotions that their families are likely to dis-
nerability to internal and external stimuli
(Broen and Storms, 1966; Lang and Buss, 1 This research project, under the direction of
1965; Payne, Mattussek, and George, 1959; Gerard Hogarty, is partially funded by Grant No.
Rabin, George, Doneson, and Jentons, MH 30750 from the National Institute of Mental
1979; Shakow, 1962; Silverman, 1972; Health.
Psychoeducational Family Therapy 147
play. For instance, communication in fami- ture, and specific coping mechanisms of use
lies of schizophrenic patients often includes in dealing with a psychotic family member.
communicative behaviors that are vague, A highly structured and directive approach
unclear, amorphous, tangential, or lacking was used to increase the predictability and
in acknowledgment (Goldstein and Rod- stability of the family environment. An ed-
nick, 1975; Jacob, 1975; Jones, 1977; Jones ucational component was included to in-
et aI., 1977; Singer and Wynne, 1965,1966; crease family knowledge about the illness
Wynne, 1961). Whether or not these com- and confidence in coping with it, thus de-
munication patterns predate the illness or creasing family anxiety about the patient
contribute to its etiology, it would seem log- and their ability to react helpfully. The pro-
ical that patients who have problems con- gram has four basic overlapping phases,
trolling and processing stimuli would have separated here for the sake of clarity. Since
difficulties coping with these complicated the entire program is discussed in more de-
and confusing family communications. tail elsewhere (Anderson, Hogarty, and
Furthermore, when patients have be- Reiss, 1980), only the major points will be
come acutely psychotic, families usually re- stressed.
port feelings of anxiety, guilt, anger, and
sadness (Hatfield, 1978; Kreisman and Joy,
Phase I: Connecting with the Family
1974). These emotions are likely to increase
the intensity of family life, and, since the ill- Based on the assumption that no interven-
ness is a chronic one, this intensity is likely tion can succeed unless the family can hear
to increase over time as family members are or use it constructively, the first phase of
unable to find ways to help the patient. It treatment, which emphasizes the establish-
might be hypothesized that family members ment of an allliance with the family, begins
in such chronic crises would come to re- immediately after the patient's admission to
spond to patients in one of the two ways the hospital. Since all families begin the
Brown describes as components of high program during a serious crisis, and most
EE: becoming overinvolved, attempting to have had multiple unsuccessful contacts
constantly monitor and protect patients with other hospitals and professionals, spe-
from themselves or the environment, or be- cial attention is given to the creation of an
coming frustrated, angry, rejecting, and atmosphere which increases the family's re-
withdrawn from patients and treatment sys- ceptivity to treatment intervention. Phase I
tems. Either of these emotional responses interventions first involve joining the family
would appear to both decrease family abil- by eliciting their reactions to the patient's
ity to cope with patient behaviors and to be illness and to past attempts to cope with it,
problematic to a patient vulnerable to in- as well as eliciting their perceptions of their
tense stimuli. In summary then, these two own current needs and problems. Hope-
forces (the patients vulnerability and the fully, these discussions communicate to
turmoil of families) probably interact to the families that therapists care about what
patient's disadvantage in a spiraling man- they have been through, are not critical
ner; the patient's vulnerability to stimuli about how families have attempted to cope
causing symptoms which upset family mem- with patients, and genuinely want to know
bers, who in turn upset the patient, and so family ideas and views of what is helpful.
on. Once the family has begun to form a rela-
Because of this hypothesized relationship tionship with the therapist, the therapist is
between patient vulnerability and family established as the family's ombudsman or
anxiety or behaviors, this program of family representative in relationship to the hospi-
intervention was designed to accomplish tal system. Since the staff of inpatient facili-
two goals: (1) to decrease the patient's vul- ties are primarily involved with the patient
nerability to stimuli through a program of on a daily basis, it is easy for them to neglect
maintenance chemotherapy and (2) to de- families or fail to see family needs. The
crease the intensity of the family environ- creation of a family representative serves to
ment through a program of providing the balance this skewed perspective and pre-
family with support, information, struc- vent the alienation of families from the tre-
148 C. M. Anderson
atment team. Thus, the family ombudsman therapy, pharmacology, megavitamins,
keeps the family informed of ward decisions homeodialysis. Every attempt is made to
about the patient, ensures the input offam- discriminate between the facts, theory, and
ily concerns and needs into treatment plan- opinion about each ofthese issues. Because
ning, and provides the family with structure medication compliance is viewed .as a cru-
and concrete help in coping with the illness cial component of the program, the impor-
and the hospitalization. In this way, the the- tance of antipsychotic medication is given
rapist also begins to mobilize the family's special attention. Mechanisms of action,
concern and involvement into constructive possible negative side effects, and the use of
attempts to help themselves and the pa- antiparkinsonian agents are explained and
tient. By the end of the hospitalization statistics about the risk of relapse on and off
(which usually is less than 3-4 weeks), the medication are shared. In particular, the
family, patient, and therapist arrive at a tre- critical importance of family support for
atment contract which roughly specifies the and feedback about the medication pro-
goals, content, length, rules, and methods gram is stressed.
of the aftercare family program. This pro-
gram, then, continues for 1-2 years after
Information About Management
patient discharge from the hospital.
of the Illness
Following the presentation of general facts
Phase II: Survival Skills Workshop
and theories, families are introduced to a
Based on the assumption that people are series of techniques for managing patients.
more anxious about what they do not un- Based on the assumption that families can-
derstand, the survival skills workshop seeks not accept staff suggestion unless they
to provide the family with as much informa- genuinely believe that the staff know how
tion as possible about the nature of schizo- hard it has been to cope with this illness, this
phrenia. The education workshop was de- discussion begins with a description of what
signed as a multiple family enterprise to families have probably done over the years
simultaneously promote deisolation of the that has not worked.
family and desensitization about the subject Following this description, families are
of mental illness. It is a daylong event at- told that while there is no firm evidence that
tended by all the members of four or five families cause schizophrenia, there is rea-
families who are new to the program. (The son to believe that families have the power
patient does not attend.) Every attempt is to influence the course of the illness. They
made to encourage an informal atmosphere are helped to see the need to create barriers
in which families can question professionals to overstimulation of the patient by estab-
and interact with one another. The work- lishing firm, clear, and approximate bound-
shop is held as early in the treatment pro- aries. Families are encouraged to set limits
cess as possible because it also serves to on unacceptable behaviors, while allowing
establish the basic themes of the entire fam- patients to set their own pace toward recov-
ily program. The workshop focuses on the ery. This theme is translated into specific
following categories of information. suggestions for responding to the patient's
fears, delusions, paranoid thoughts, obses-
sive rituals, or threats of violence. Finally,
Information About the Illness
families are strongly encouraged to avoid
The most recent data about the phenome- centering their lives around patients. They
nology, onset, treatment, course, and out- are asked to attend to their own needs, the
come of schizophrenic disorders is present- needs of other family members, and to mo-
ed in clear, understandable language. bilize a social support network to maintain
Theories of etiology, ranging from genetic their own ability to cope and survive over
and biochemical to family and cultural, are time.
explained. What is known about the pro-
gnosis of the illness is also outlined, as are
various methods of treatment: psycho-
Psychoeducational Family Therapy 149
Phase DI: Reentry and Application their expectations of patients. Since pro-
of Workshop Themes gress on these issues is exceedingly slow, a
great deal of support is given to family
Highly structured low-key individual family members to enable them to tolerate inactiv-
sessions are held as soon as the acute phase ity, amotivation, and apathy.
of the illness has been controlled sufficient-
ly to enable the patient to attend. Once pa- Phase IV: Continued Treatment
tients have left the hospital, these sessions or Disengagement
occur once every 2-3 weeks. The interven-
tions of these sessions are based on the Once the goals for effective functioning
themes established in the survival skills have been attained (and these goals differ
workshop and relate largely to the reinfor- depending on the patient's abilities, the
cement of family boundaries and the gradu- length of impairment, and tolerance level of
al resumption of responsibility by the pa- families), the model calls for the family to
tient. be presented with two possible options for
Three kinds of boundaries are stressed on treatment: (1) more traditional family-
an ongoing basis. The interpersonal bound- oriented treatment to resolve long-term
aries between family members, the gener- family conflicts of unfinished business or (2)
ational boundaries between parents and periodic supportive maintenance sessions
offspring, and the family boundary with the of gradually decreasing frequency.
larger social community support system. The first three phases of this model of
The first two types of boundaries are rein- family intervention do not offer families the
forced, largely by encouraging families to opportunity to deal with family issues and
establish clear expectations, rules, and problems that do not immediately relate to
limit-setting processes. The third type of the patient's survival in the community. In
boundary, that between the family and the fact, the model specifically discourages the
community, is minimized by stressing the discussion of upsetting topics, such as mari-
family's need for the development of a tal discord, unresolved losses, or major
support system beyond the nuclear family. moves toward emancipation. Nevertheless,
Over time, patients are gradually en- some of these issues could interfere with the
couraged to assume more responsibility for ongoing growth and development of family
their lives and functioning. Initially, the en- members, and once the crisis has passed,
tire treatment focus is on the patient's sur- family members are offered the opportuni-
vival outside of the hospital. As signs of life ty to devote their energies to resolving
begin to occur in patients, the sessions gra- them. Unless it is thought that the issues
dually emphasize a return to effective work have direct and immediate impact on the
and social functioning. This is initially ac- patient's progress, families are to be offered
complished by the assignment of small hou- a choice about this phase of treatment since
sehold tasks or tasks which involve a mini- contracting to help the patient is. not
mal amount of socialization with outsiders. thought to give the right to unilaterally de-
Later, more ambitious tasks are assigned, termine the family's general goals or meth-
and families are encouraged to increase ods of attaining them.

Preliminary Results
Results for the 1st year of treatment using no patient in the treatment cell which re-
this model have been encouraging. Among ceived both family therapy and social skills
treatment takers (n = 88), 19% ofthose re- training experienced a relapse. In contrast,
ceiving family therapy alone experienced a nearly 36% of those receiving chemothera-
psychotic relapse in the year following hos- py and support relapsed. When all assigned
pital discharge. Twenty-one percent of patients were studied (n = 102), only a sig-
those receiving an individual behavioral nificant effect for family therapy could be
therapy (social skills training) relapsed, but identified in lowering relapse. Most impor-
150 C. M. Anderson
tant, when patients who were entirely faith- feel that investigators familiar with the EE
ful in adhering to their maintenance chemo- method and associated family therapists
therapy were included, a clear and signifi- (ourselves included) have succumbed to a
cant effect for family therapy was observed. profound error in judgment in limiting
Analyses regarding the adjustment of these these modern interventions to high EE pa-
patients are not complete as of this writing, tients and their families. High EE, it seems,
but in general, there is no evidence that has become the exclusive definition of high
family therapy or social skills training are risk in these studies. Admitting patients to
simply maintaining poorly adjusted patients studies who come from high EE houses por-
in the community just to make the relapse tends to place under observation essentially
rates "look good". If anything, clinical a group of unmarried males living in paren-
judgments regarding the "degree of illness" tal homes. In our own studies, this group
and "change in clinical state" pre- and post- represents but a subsample of the "at risk"
treatment reveal a significant effect for fam- schizophrenic population. Other samples,
ily therapy. (There is also a trend suggesting including married and unmarried females,
better role performance for social skills pa- are also at high risk for relapse, and we
tients as well.) Studies conducted at the believe these subgroups might also profit
University of Southern California by Fal- from these interventions.
loon's group (Chap. 14) and in London by We surmise from the results we have
Leff's group (Chap. 13) revealed that 6% achieved so far that the primary effect of
and 9% of family therapy-treated patients, family treatment is a prophylactic one and
respectively, experienced a relapse by 9 that these experimentally treated patients
months, but that 44% and 50% of controls are not simply being maintained in the com-
treated with drug and individual therapy munity in a more impaired condition. Al-
had relapsed by 9 months. Thus, there ap- though both family treatment and social
pears to be an increasingly broad validation skills training are useful, a limitation of the
of the effectiveness of family approaches, at social skills training approach seems to be
least in the forestalling of a psychotic re- its inability to engage or maintain patients
lapse. This, in turn, increases the potential who are actively psychotic at the time of
for helping the patients to be integrated discharge. The family approach, however,
within the communities. appears to buy time for patients, permitting
We do not, however, wish to be intem- them to more fully recover by decreasing
perate in our claims. The results, at least family distress, educating them about the
from our own study, have demonstrated illness, reducing their expectations and uni-
that these approaches forestall relapse but tary views of the illness, and otherwise in-
in no way provide "prevention" per se. To corporating new coping strategies. How-
date, relapse rates continue to rise as pa- ever, in facilities with long-term hospital-
tients near the end of their 2nd year of treat- izations or who otherwise discharge pa-
ment. An uncensured estimate of relapse tients in a more clinically stable condition,
into the 2nd year of treatment reveals that both family therapy and social skills trai-
25% of family therapy alone patients, 35% ning might well be effective interventions in
of social skills training alone patients, 22% significantly lowering schizophrenic re-
of the combined treatment patients, and lapse. The combined treatment approach
57% of drug-treated controls have ex- provides an additional and important pro-
perienced a relapse to date. Further, we phylactic advantage.

References
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Schizophrenia Bulletin, 6 (3), 490-505. and lifes change and the onset of schizophrenia.
Broen, W. E., and Storms, L. H. (1966). Lawful Journal of Health and Social Behavior, 9,
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Brown, G. W., Birley, J. L. T., and Wing, J. H. Payne, R. W., Mattussek, P., and George, E. I.
(1972). The influence of family life on the (1959). An experimental study of schizophren-
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Goldstein, M., and Kopeikin, H. (1981). Short (1979). Studies of psychological functions in
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May, P. R., and Steinberg, M. (1978). Drug Singer, M. T., and Wynne, L. C. (1965). Thought
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(5),355-359. search Reports, 20, 25-38.
Jacob, T. (1975). Family interaction in disturbed Tecce, J. J., and Cole, J. O. (1976). The distrac-
and normal families: A methodological and tion-arousal hypothesis, CNV and schizophre-
substantive review. Psychological Bulletin, 82, nia. In: D. I. Mostofsky (ed.). Behavior control
33-65. and modification of physiological activity. Eng-
Jones, J. E. (1977). Patterns of transactional style lewood Cliffs, NJ: Prentice-Hall.
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Jones, J. E., Rodnick, E., Goldstein, M., course of psychiatric illness. British Journal of
McPherson, S., and West, K. (1977). Parental Psychiatry, 129, 125-137.
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Kreisman, D. E., and Joy, V. D. (1974). Family pp. 1-47). New York: Academic Press.
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Lang, P. J., and Buss, A. H. (1965). Psychologic- Press.
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tivation. Journal of Abnormal Psychology, 70, gnments and splits in exploratory family thera-
77-106. py. In N. Ackerman, F. Beatmen, S. Sherman
Leff, J., and Vaughn, C. (1980). The interaction (Eds.), Exploring the base for family therapy
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in schizophrenia and depressiv neurosis. Brit- sociation of America.
ish Journal of Psychiatry, 135, 146-153.
13. Controlled Trial of Social Intervention in the
Families of Schizophrenic Patients
J. Leff, L. Kuipers, R. Berkowitz, R. Eberlein-Vries, and D. Sturgeon

Introduction
A robust association has been established these results is reproduced here (Figure 1).
between the level of expressed emotion These issue of the direction of cause and ef-
(EE) shown by relatives and the outcome of fect in the relationship between relatives'
schizophrenia in patients living with them EE and patients' relapse has been ap-
(Brown, Monck, Carstairs, and Wing, proached by using statistical techniques to
1962; Brown, Birley, and Wing, 1972; define the role of possible mediating fac-
Vaughn and Leff, 1976a; Leff and Vaughn, tors, such as patient's disturbed behavior.
1981). Relapse of schizophrenia is more The possibility that such behavior might
likely if patients live with relatives who are lead both to high EE in relatives and to re-
excessively critical and/or overinvolved. lapse in the patients was eliminated by a
Such relatives are designated as high EE. variety of statistical approaches (Brown et
Two factors appeared to operate in a pro- aI., 1972; Vaughn and Leff, 1976a). How-
tective manner for patients living whith ever, a causal relationship between high EE
high EE relatives. These were regular and schizophrenic relapse and low EE and
maintenance therapy with neuroleptic patients remaining well can only be de-
drugs and the establishment of a social dis- monstrated convincingly by an experiment
tance between patient and relative, as mea- in which relatives's EE is manipulated and
sured by the amount of face-to-face contact patients' relapse rate is monitored. The
during a typical week. Furthermore, these same argument applies to the possible pro-
two factors seemed to be additive in their tective nature of low face-to-face contact,
protective effect. The evidence for these which can only be established beyond doubt
conclusions was derived from an analysis of by an experimental approach. This paper
pooled data from the two most recent stu- reports an experiment directed at both
dies (Brown et aI., 1972; Vaughn and Leff, these issues.
1976a). The relevant figure setting out

Method
and a staff member, however trivial, has
Design
therapeutic potential, even a standardized
The problems to be surmounted in design- assessment procedure. We recognize that
ing a controlled trial of any social therapy there is no ideal solution to all the inherent
have been explored in detail by Leff (1981). problems, but present our design as the op-
The double-blind placebo controlled drug timum under the circumstances.
trial is a sound basis to start from, but a We chose to study patients at highest risk
number of modifications are necessitated of relapse, represented by subgroup 6 in
by the nature of social treatments. For ex- Figure 1. Virtually all these patients not
ample, there is no placebo for a social treat- taking regular medication and living in high
ment. Any interaction between a patient contact with high EE relatives relapsed
154 J. Leff et al.
Subgroups

LowEEI3%

Face-to-face contact
! 1. On drugs

2 Not on drugs
12%

15%

!
Total group 3. On drugs 15%
<35h28%

} 4. Not on drugs 42%

!
HighEE51%
>35 h 69% 5. On drugs 53%

6. Not on drugs 92%

Fig. 1. Nine-month relapse rate of total group of 128 schizophrenic patients.


Note. From "The Influence of Family and and Social Factors on the Course of Psychiatric Illness. A
Comparison of Schizophrenic and Depressed Neurotic Patients" by C. E. Vaughn and J. P. Leff, 1976,
British Journal of Psychiatry, 129, pp. 125-137.

over the course of 9 months. In view of the the effect on relapse rate of altering rela-
proven efficacy of maintenance neuro- tives' EE from high to low (compare sub-
leptics in preventing relapse of schizophre- groups 1,2, and 3). Hence, the aims of so-
nia (Leff and Wing, 1971; Hogarty and cial intervention were to reduce face-to-
Goldberg, 1973), we considered it unethical face contact below the crucial level of 35 hi
to withhold such drugs from these high-risk week (Brown et aI., 1972) and/or to change
patients. Our strategy then was to ensure relatives' EE from high to low. A range of
that all patients entering the trial received strategies that might be expected to achieve
maintenance neuroleptics in the form of these aims has been set out by Leff (1976).
long-acting injections, to eliminate prob- One possible design for our trial was to as-
lems with compliance. Patients were then sign experimental families randomly to a
randomly assigned to an experimental variety of social interventions, for example,
group, which received the social interven- an educational program, family sessions, or
tion, and a control group, which received behavioral modificaton. We decided that
routine outpatient care. In considering the this was too ambitious in terms of the num-
design, we were faced with the choice of bers required and instead compiled a pack-
administering a nonspecific social treat- age of social interventions which was to be
ment of the control group or allowing their applied flexibly according to the needs of
responsible clinicians to treat them accord- each family. Thus, we set out to compare
ing to their usual practice. Both procedures the relative effectiveness of this package
have their drawbacks, and we chose the lat- with routine outpatient care with the expec-
ter, recognizing that we would need to es- tation that if it did prove to be superior, the
tablish that the treatment experiences of ex- individual elements could be evaluated sep-
perimental and control families were sub- arately in a subsequent trial.
stantially different (cf. Orford and Ed- The intervention basically consisted of
wards, 1977). three elements: an education program, a
relatives' group, and family sessions.
Package of Social Interventions
Education Program
It can be seen from Figure 1 that, provided
low social contact is genuinely protective, This consisted of four lectures on the etiol-
reduction in face-to-face contact between ogy, symptoms, course, and treatment and
high EE relatives and patients on medica- management of schizophrenia. We put a lot
tion should reduce the relapse rate from of thought into the writing of these lectures,
53% to 15%. This would be equivalent to which incorporated our consensus opinions
Controlled Trial of Social Intervention 155
on the above topics, couched in everyday curred after each group meeting.
language with a strict avoidance of jargon. Other reasons for setting up the group in-
The lectures were read out from a type- cluded the need to counter the sense of
script to each relative in his or her home. isolation felt by many relatives of schizo-
Initially four visits were made, one for each phrenic patients, the possibility that the
topic, but after a few relatives had been in- group would allow relatives to discharge
structed in this way, we decided it would be emotions that would otherwise be directed
preferable to give two lectures at a time. at the patients, and the fact that it was eco-
Following each lecture, we allowed unlimit- nomical of resources. The group was con-
ed time for the relative to ask questions. structed to be flexible both in regard to
This element in the package was in fact membership and attendance. Relatives
evaluated separately by means of a knowl- were inducted into the group as the patients
edge interview, administered before and entered the study. The group met every 2
after the education program. This is pres- weeks in a large, comfortable room in the
ented in detail under "assessments." Institute of Psychiatry for 1.5 h, and rela-
tives attended when they could. They were
encouraged to attend for the 9 months of
Relatives' Group the study period, but were free to continue
This was originally conceived of as a way of thereafter if they wished, and a number car-
bringing together high EE and low EE rela- ried on coming for over 1 year. The group
tives. In addition to the family emotion stu- had a maximum of seven members at any
dies, we had evidence from psychophysio- one time and included two professionals for
logical studies (Tarrier, Vaughn, Lader, most of the study, but latterly only one. Our
and Leff, 1979; Sturgeon, Kuipers, Berko- experience with the group is presented in
witz, Turpin, and Leff, 1981) that low EE more detail elsewhere (Berkowitz, Kui-
relatives had found way of coping with the pers, Eberlein-Fries, and Leff, 1981). Each
everyday problems of living with schizo- session was taperecorded, with permission
phrenic patients that not only avoided dis- of the relatives, for future analysis.
tressing the patients but provided them with
active support. Family Sessions
It was our intention to use the group as
a means of altering the coping styles of high Because the relatives' group was not ap-
EE relatives so as to resemble more closely propriate for dealing with the whole range
those of low EE relatives. Some of the of problems or for dynamic work and be-
problems that relatives face were known cause patients were excluded from it, we
from Creer and Wing's (1975) study. Priest- felt that it needed to be complemented by
ley's experiences with a similar group of rel- sessions with the whole family. Conse-
atives were also valuable (Priestley, 1979). quently, we saw each family in their own
Given this information, the group was de- home on a minimum of 1 and a maximum of
liberately set up so that the therapists acted 25 occasions. The sessions, which lasted
as facilitators. Both high EE and low EE 1 h, were conducted by two professionals, a
relatives were encouraged to bring their male psychiatrist and a female psychologist.
problems and their solutions to the meeting Where the key relative was a spouse, we
and share them with others in a similar posi- saw the patient and spouse together. Where
tion. The purpose of this was to enable parents were involved, we saw the patient
them to learn about coping strategies of with both parents if available, and adult sib-
which they were unaware and finally to help lings were also encouraged to participate.
them try a different approach at home. The At the beginning of the study, the value
focus of the group was thus on potential or of family therapy was not well established,
actual difficulties that relatives experienced particularly for the families of schizophreni-
and not primarily on interpretations of the ic patients. Consequently, we adopted a
relatives' own behavior. This latter was pragmatic approach, guided by our princi-
more useful in discussions between the pro- pal aims of reducing EE and/or social con-
fessionals about the group process that oc- tact. Techniques used to achieve these aims
156 J. Leff et al.
Admission Discharge
'V V
1st 2nd 3rd
Proce- knowledge Education knowledge Relatives' Family Follow-up knowledge
dures PSE EE interview interview program interview group sessions EEandPSE interview
Experimental + + + + + + +
High
Control + + + +
Experimental + + + + + +
Low
Control + + + +
_ _ _ _ _ _ _-'9 months..s_ _ _ _ _ __

Fig. 2. Flow chart of intervention program.

in family sessions varied from dynamic in- Having passed these screens, patients
terpretations to behavioral interventions. then entered the study, and demographic
Before each session, we discussed and for- and historical data were collected with a
mulated our objectives, but we could be standardized schedule. Relatives in high
diverted from these if other important is- face-to-face contact with the patient (al-
sues emerged in the course of the visit. Each most invariably a spouse or parents) were
session was discussed afterward and a quite interviewed with the abbreviated form of
detailed account written up. the Camberwell Family Interview (Vaughn
In addition to these formal contacts, and Leff, 1976b). Ratings of the four main
some relatives phoned up one or other of us components of EE, criticism, hostility,
on several occasions. We kept careful rec- warmth, and overinvolvement, were made
ords of all such contacts to calculate the from taperecordings of the interviews. Rel-
total amount of professional time taken up atives with a score of six or more critical
by each family. comments, any degree of hostility, or a rat-
ing of 3 or more on overinvolvement1 were
assigned to a high EE group. The further
Assessments
assessments and procedures than ensued
All patients between the ages of 16 and 65 are shown on a flow chart in Figure 2.
admitted to the Bethlem and Maudsley The knowledge interview was specially
Hospital, the Southwestern Hospital, and constructed to test the effect of the educa-
the North Wing at St Pancras Hospital were tion program. It consisted of 21 questions
screened regularly. If they had lived with directly related to the basic information
relatives continuously for 3 months before given in the program. It was administered
admission, resided within reasonable com- before and after the program to experimen-
muting distance from the hospital con- tal high EE and low EE relatives and at the
cerned, and appeared from the case notes same interval to the control relatives. The
to be suffering from a functional psychotic knowledge interview was given a third time
illness, they were interviewed with the Pres- to all relatives at the end ofthe 9-month fol-
ent State Examination (PSE) (Wing, Coo- low-up.
per, and Sartorius, 1974). The PSE data Immediately following the first knowl-
were processed by the CATEGO program, edge interview, a joint interview was held
and those patients assigned a diagnosis of with the relative and patient in a studio.
schizophrenia were included in the trial if in This allowed us to make a videotape record-
addition they spent more than 35 hlweek in ing of the interview, during which certain
face-to-face contact with one or more rela-
tives. This was determined by constructing 1 The crucial level of overinvolvement was lower-
a time budget of a typical week from an in- ed from 4 to 3 prior to the study in the light of
terview with the patient, or failing that with more extensive experience with this rather in-
a relative (Brown et al., 1972). frequent attitude.
Controlled Trial of Social Intervention 157
psychophysiological measures of the pa- a more subjective judgment than the first
tient's respones were made. The data from kind of relapse and hence may be influ-
these interviews will be presented else- enced by the interviewer's bias. Unfortun-
where. ately, it was not possible to maintain blind-
The next step was to give the education ness to each family's status as experimental
program to the experimental high EE and or control because the research team was
low EE relatives. When this was com- both conducting the intervention and mak-
pleted, the relatives were invited to join the rng the assessments. This deficiency in the
relatives' group. At about this time, most design could only have been remedied by a
patients were close to discharge from the considerable increase in staff, which was
hospital. For all high EE families, the clin- not feasible. However, there were a num-
icians responsible for the patients were in- ber of safeguards against the influence of
formed of their high risk of relapse and bias. The key assessments, EE and the
were asked to prescribe long-acting neuro- PSE, were made by researchers who were
leptic medication if possible. It must be extremely experienced in the use of the
appreciated that patients remained under techniques and had been trained to a high
the care of their usual clinician. Our thera- level of interrater reliability.
peutic interventions with the experimental The assessment of EE was usually con-
families were conducted in parallel with the ducted independently by two raters. Where
patients' ordinary clinical care and de- they disagreed or where the rating was par-
pended on a close liaison with the clinical ticularly crucial, the recording was sent to
team. This was usually, but not invariably, a Dr Christine Vaughn, who rated it blindly.
successful arrangement. In addition, a representative selection of
Just before discharge, the patient's clin- eight follow-up interviews was rated blindly
ical state was assessed. If it was clear that by Dr R. Gosh, who had been trained in the
the psychosis had completely resolved, an assessment of EE. His reliability with the
informal assessment was carried out. How- definitive raters was calculated using the
ever, if there were any residual pychotic product moment correlation coefficient and
symptoms, a full PSE was conducted and was found to be 0.88 for critical comments
served as a baseline for any subsequent and 0.90 for overinvolvement. He agreed
change. Following discharge, virtually all with the definitive raters on the assignment
the patients attended outpatient clinics on a to high or low EE in seven of the eight
regular basis. A note was affixed to their cases. In the eighth case, he rated one ex-
case records asking the responsible clini- perimental mother as marginally high on
cian to contact the research team if there criticism whereas she had been rated as low
was any suggestion of an impending or by both definitive raters independently.
actual relapse. As a result, it was possible to With regard to the PSE ratings, these
see all but one of the patients who suffered were not done blindly in the case of a type 1
a recrudescence of symptoms at an early relapse. However, for possible type 2 re-
stage in their relapse. A full PSE was per- lapses, an independent rater, Dr Paul Beb-
formed at the time and a history of life bington, was recruited to make the assess-
events taken for the 3 months prior to re- ments blindly. He did not always concur
lapse (Brown and Birley, 1968). with the view of the patient's clinician that a
For the purposes of the research, relapse relapse had occurred.
was defined as a recurrence of schizophren-
ic symptoms as detected by the PSE, in pa-
Follow-up
tients who had been free of them at dis-
charge (type 1 relapse of Brown et al., All patients in the trial were followed up at
1972). For the small proportion of patients 9 months after discharge. If they had not al-
who still had active schizophrenic symp- ready relapsed, a PSE and life events his-
toms at discharge (two experimental, three tory were administered. The relative or rel-
control), relapse was defined as a marked atives were reinterviewed with the Camber-
increase in the number or intensity of symp- well Family Interview, if possible by the
toms (type II relapse). This clearly involves same person as on the first occasion, and
158 J. Leff et al.
EE was rated. The time budget was also A 2-year follow-up has also been initia-
repeated. A history of medication taken by ted, the results of which will be presented
the patient during the preceding 9 months when it is completed.
was obtained.

Subjects
nificant difference between the two groups,
Characteristics of Patients
once more confirming the truly random
Over the course of 4 years, 49 patients pas- nature of patient assignment. In terms of
sed the screening criteria for the trial. The CATEGO classes, 11 patients in each
number is so small because our selection group were labeled S+ (schizophrenia),
procedures for high-risk patients eliminated while the remaining patient in each group
more than two of every three admissions for was classified as P+ (paranoid psychosis).
schizophrenia. Of those families ap-
proached, nine (18%) refused to take part
Characteristics of Relatives
in the study. Of the remainder, 24 lived with
high EE relatives and actually participated In the experimental group, six patients
in the trial. The randomization procedure, lived with a spouse and six with parents. In
using a table of random numbers, segregat- the control group, six lived with a spouse,
ed them into 12 control and 12 experimental five with parents, and one with her sister.
families. Relatives who were found to be Some patients in both groups lived with a
low EE from the Camberwell Family Inter- single parent, and in some households one
view were also randomly assigned to ex- of the parents was in low face-to-face con-
perimental and control groups for the pur- tact with the patient, in which case they
pose of assessing the effects of the educa-
tion program (see Figure 2). In addition,
the low EE experimental families were en- Table 1. Demographic and Historical Charac-
couraged to join the relatives' group, in ac- teristics of Patients
cord with the principal therapeutic aim of Experi- Control
identifying and using their coping skills as a mental
model.
Number 12 12
Male/female 6/6 6/6
Demographic and Historical Data Living group: parents 6 6
spouse/sibling 6 6
The experimental and control patients were Mean age 39 30
compared on a large number of demo- Education: CSE or above 4 4
graphic and historical features as shown in Ever married 6 7
Table 1. Except for unemployment, which Ever divorced or separated 1 2
was worse in the experimental group, none Mean number of children 0.8 1.3
of the items differed significantly between Drop from highest sociosexual
the two groups, endorsing the effectiveness achievement 3 2
ofthe randomization procedure. Occupation: nonmanual or
above 6 2
Mean length of unemployment
Clinical Data before admission in months 16.5 4.8'
Employed at admission 4 7
The PSE data were processed by the Abnormal premorbid
CATEGO program and a print-out ob- personality 8 5
tained of syndromes and of diagnostic clas- First admission 4 4
ses. The experimental and control patients Mean number of previous
were compared for the presence or absence admissions 2.3 1.2
of each of the 38 syndromes using Fisher's Age at first onset 33 27
exact test. For no syndrome was there a sig- • P<0.05.
Controlled Trial of Social Intervention 1S9
Table 3. Overinvolvement Scores of Experimental and Control Relatives
Number of relatives Mean number of critical comments
with six or more
critical comments At9-month
initially Initially follow-up

Experimental 12 15.8 6.S t=3.37,P<0.00S


Control 8 12.0 10.7 NS
NS NS

Table 2. Critical Comments of Experimental and Control Relatives

Mean overinvolvement score


Number of relatives
scoring 3 or more At9-month
on overinvolvement Initially follow-up

Experimental 5 4.0 2.4 t=2.36,0.1 >P>O.OS


Control 6 4.0 3.7 NS
NS NS

were not interviewed for an EE assessment. scores for these individuals are shown in
A total of 13 relatives in the experimental Tables 2 and 3. There were no significant
group and 13 in the control group were differences between the groups on these
rated on EE. The mean number of critical measures.
comments and the mean overinvolvement

Results

Social Intervention
only one family had as many as 25 sessions.
Two relatives did not attend the group at In addition to the formal contacts of the
all. One, a wife, attended for the first time relatives' group and family sessions, rela-
on the only occasion when no other rela- tives were encouraged to phone members
tives turned up. She was given a one-to-one of the team whenever they felt the need.
session with the therapist and declined This facility was not abused as a total of 10
further attendance or contact. She was the relatives used this method of contact be-
only relative who did not receive the educa- tween 2 and 19 times, the mean being 7.5
tion program. The other, a husband, was times.
managing a business which demanded his Apart from our own efforts to work with
presence at the time the group met. The re- the relatives in the experimental group, the
maining 11 high EE relatives attended the clinical team responsible for the patient's
group an average of 9.1 times ranging from care provided some input in two cases. For
6- 21 times over the 9-month follow-up pe- one married couple, the clinical team's so-
riod. The number of relatives present at cial worker acted as a co-therapist with
each session varied from two to seven, with one of the research psychologists, as he
a mode of four. wished to gain experience of mariti thera-
Family sessions in the home wee held for py. Another married couple received mari-
all families. The number of sessions ranged tal therapy from the clinical psychiatrist in
from 1 to 25 with a mean of 5.6. However, parallel with our own family sessions. We
160 J. Leff et al.
took pains to maintain a close liaison with went through the planned assessment pro-
this therapist. cedures at the 9-month follow-up. 2-year
The therapeutic experiences of the con- follow-up has been completed and will be
trol relatives were studied by consulting the presented elsewhere (Leff, Kuipers, Ber-
case notes of the patients as well as ques- kowitz, and Sturgeon, in press).
tioning the relatives at follow-up. The control relatives were not as cooper-
ative as their experimental counterp!lrts,
probably because we offered them no help.
Treatment Experiences of Control
Two of the 13 originally interviewed re-
Relatives
fused a second EE interview, and one, a
In eight cases, no therapeutic help was husband, had left his wife and was unob-
given to the relatives. In two cases, the rela- tainable. Thus the success rate for follow-
tives themselves were seen by a psychiatrist up was 77%.
to receive treatment for overt symptoms. The mean number of critical comments
One relative, the mother of a schizophrenic and the overinvolvement scores obtained at
girl, was discovered to suffer from schizo- follow-up are shown in Tables 2 and 3. It is
phrenia herself and was treated as an outpa- evident that there has been a highly signifi-
tient with a neuroleptic drug. She attended cant reduction in criticism in the experi-
a total of 11 times in the course of 9 months, mental group over the 9-month period of
but the focus of treatment was on her psych- social intervention. Five experimental rela-
iatric condition rather than on her attitudes tives changed from high to low criticism,
toward her daughter. The other relative to while three others showed some decrease.
receive treatment was a husband who be- Only three critical relatives remained vir-
came depressed and was seen as an outpa- tually unchanged. By contrast, there was a
tient on several occasions over 2 months. small and nonsignificant reduction in the
Two further families received help from number of critical comments made by the
social workers. In one family, this took the control relatives. This was entirely account-
form of a single family session held during ed for by two relatives, one a spouse and
the 9th month after the patient was dis- one a sister, who changed from high to low
charged with the aim of persuading him to criticism. As neither relative had received
attend a day hospital. In the second family, any therapeutic help from professionals,
the wife of a schizophrenic patient was seen this almost certainly represents a spontane-
every 2 weeks by a psychiatric social work- ous alteration in attitude.
er, and one family session was held during We can conclude from these data that our
the 9 months. The social worker wrote that package of social interventions met with
"my interviews with her have had the object considerable success in ameliorating critical
of providing her with some support through attitudes in the experimental relatives. The
helping her to share her feeling of responsi- same cannot be said for emotional overin-
bility for maintaining her husband's pro- volvement. There was a drop in the mean
gress." He gave her some advice on how to overinvolvement score for the experimental
handle her husband's behavior that stem- relatives, as can be seen from Table 3, but
med from his delusions. It is only in this this failed to reach an acceptable level of
single case of the 12 controls that profes- significance. In terms of individuals, two
sional help to the relatives approximated relatives altered from high to low scores on
that received by the experimental families. overinvolvement. One of these, the only
It is worth noting that in this control case spouse to show overinvolvement in the ex-
the wife's level of overinvolvement actually perimental group, underwent a particularly
rose during the follow-up period, although dramatic change from a score of 4 to zero.
her husband reduced his contact with her to Two others achieved a lower score, but did
a low level. not drop below 3, while one relative showed
no change. By contrast, none of the overin-
volved control relatives fell below 3 on this
FoUow-up Relatives
scale, while one relative actually changed
All relatives in the experimental group from low to high during the follow-up period.
Controlled Trial of Social Intervention 161
At follow-up, face-to-face contact had of neuroleptics and received these regularly
fallen below 35 hlweek in six experimental as prescribed. One control patient with a
relatives, two being the parents of one pa- first episode of a paranoid psychosis was
tient. In one patient, this reduction resulted prescribed oral trifluoperazine, which he
from his getting a full-time job and in anoth- took religiously, while one experimental
er from attendance at a day hospital, while patient could not tolerate the side effects of
the remaining three made alterations in the injections and was transferred to oral med-
ways they spent their leisure time. Low con- ication. She also adhered meticulously to
tact was also found at follow-up in three her drug regime.
control families, which is not significantly
During the 9-month follow-up, relapse
different from the proportion in experi-
occurred in seven patients, six of them in
mental families. However, in two of these,
the control group. All relapse were type 1 in
the way in which this was achieved was dif-
nature. In six patients, the relapse took the
ferent from that in the experimental group.
form of a florid episode, similar if not ident-
One patient's husband left her during the
ical to the previous one. Three of these pa-
follow-up period, while another patient
tients were readmitted to the hospital. The
began spending most of his leisure time
seventh patient, a control case, had been
alone in his room. The third patient de-
free of auditory hallucinations, which re-
veloped more leisure interests which took
turned abruptly. The relapse rate in the
him out of the parental home.
control group was 50%, while the rate in the
As stated earlier, the aims of the social in-
total experimental group was 8% (exact
tervention were to lower EE and/or face-to-
P = 0.032). Hence, the package of social
face contact below certain crucial levels. interventions produced a significant reduc-
Reduction of EE was achieved in five famil- tion in relapse rate of schizophrenia. Furth-
ies and reduction of contact also in five fam-
er light is thrown on the specificity of the
ilies, but there was some overlap, as can be
interventions by comparing the relapse rate
seen in Table 4.
in the control group with that of the patients
As a consequence, one or both of our
in whose families we achieved one or both
aims were met in 9 of the 12 families with
of the aims of social intervention. In fact, in
follow-up completed to date. Hence, social
these nine families not a single patient re-
intervention was successful with 75% of
lapsed, a difference from the relapse rate in
families. the control group of even greater signifi-
cance (exact P = 0.017).
FoUow-up Patients The single experimental patient who re-
In each group, all but one of the patients lapsed was living in high contact with her
were maintained on long-acting injections mother, who was both highly critical and

Table 4. EE and Face-to-Face Contact at Follow-up in Experimental Group.

Patient code number Relative EE Face-to-face contact


1 Mother Low Low
1 Father Low Low
7 Husband Low High
13 Wife High High
30 Wife Low Low
31 Wife High Low
40 Wife Low High
41 Mother Low High
45 Husband High Low
49 Mother High Low
53 Mother High High
55 Mother High High
61 Mother Low High
162 J. Leffetal.
extremely overinvolved. The patient was In the control group, as already mention-
burdened with two handicaps, since in addi- ed, two relatives spontaneously changed
tion to schizophrenia she also had Turner's from high to low EE between the initial as-
syndrome and was of conspicuously short sessment and the follow-up. In neither
stature. household did the patient relapse.

Discussion
The screening procedure for our trial was Rodnick, Evans, May, and Steinberg
calculated to select patients with schiz- (1978), Hogarty, Goldberg, Schooler, and
ophrenia who were at high risk of relapse. Ulrich (1974) and Hogarty, Schooler,
The effectiveness of the procedure was sub- Ulrich, Mussare, Ferro, and Herron (1979)
stantiated by the relapse rate of 50% over 9 satisfy reasonably stringent scientific crite-
months in the control group, despite the ria. Goldstein and his colleagues studied
fact that they were all maintained regularly schizophrenic patients in their first or se-
on neuroleptic drugs. The significantly and cond admission so that it is inevitable that
substantially lower relapse rate of 8% in the their average age, 23, was considerably
experimental group provides evidence for lower than that of our sample, 35. Their pa-
the therapeutic effectiveness of our pack- tients were discharged after an admission of
age of social interventions. However, we only 1-2 weeks on long-acting injections of
did not achieve our aims of lowering EE fluphenazine. The experimental subjects
and/or social contact in every family, but received six sessions of crisis-oriented fami-
only in three-quarters of them. It is notable ly therapy, with the primary goal of helping
that in this smaller group of nine families no the patient and significant others use the
patient relapsed. The single relapse of an events of the psychosis to adjust to the ill-
experimental patient occurred in one of the ness. At a 6-month follow-up, no patient in
three families in which neither EE nor so- the drug plus family therapy group had re-
cial contact was lowered to the target level. lapsed, whereas the relapse rate among pa-
This shows that the achievement of one or tients who received the drug alone was 18%
both of our stated aims was crucial for a (P = 0.04). The interpretation of this result
therapeutic effect. is slightly clouded by the fact that the thera-
The specificity of our therapeutic en- py received by both groups was not stand-
deavor in totally preventing relapse of schi- ardized after the initial6-week trial period.
zophrenia in a high-risk group over 9 In the two studies of Hogarty and his col-
months provides unequivocal evidence leagues, social therapies were also added to
both for the causal influence of high EE rel- maintenance neuroleptic drugs in a con-
atives on relapse and for the protective ef- trolled design. Their patients were more
fect of lowered social contact between pa- like ours than were Goldstein's, being
tient and relative. Our tentative interpreta- mainly chronic and having a median of
tion of the data in Figure 1 (Vaughn and three previous hospital admissions. In the
Leff, 1976a) now takes on a definitive sta- first study, the social therapy was a com-
tus, all the more so because the relapse bination of intensive social casework and
rates predicted from the Figure were so vocational rehabilitation counseling, while
close to the actual rates (53% cf. 50%,15% in the second it comprised intensive individ-
cf.8%). ual and family social casework. In neither
It needs to be emphasized that our find- study did the social intervention significant-
ings not only constitute evidence for the ly reduce the relapse rate when added to
causal influence of relatives' EE on the maintenance drugs. However, it did appear
schizophrenic process in patients, but also to confer an advantage on the patients in
substantiate the effectiveness of a form of the 2nd year of the follow-up, no relapse oc-
social intervention with these families. To curring during this period among patients
date, the evidence for this has been some- receiving social therapy and drugs in both
what sparse. Only the studies by Goldstein, studies.
Controlled Trial of Social Intervention 163
Our result is thus closer to that of Gold- detectable by monitoring the patients' auto-
stein et aI., although we were studying a nomic responses (Tarrier et aI., 1979; Stur-
more chronic population in remission rath- geon et aI., 1981). An "arousal" hypothesis
er than in the throes of a psychosis, and fur- has been proposed to accommodate these
thermore our subjects were selected to re- findings and work has recently begun using
present a particularly high-risk group. This this paradigm to study cortical psycho-
difference is pointed up by comparing the physiology.
relapse rate of our control group over 9 There are a number of practical issues,
months, 50%, with that of Goldstein's con- the first of which concerns our failures in
trol patients over 6 months, 18%. the experimental group. With hindsight
Our findings have important implica- could we have been more effective in work-
tions, both theoretical and practical. On the ing with the three families concerned, bear-
theoretical side, now that the role of rela- ing in mind our lack of experience with
tives' emotional attitudes has been firmly these kinds of families when we began the
established in the causation of schizophren- study? The answer for one family is possibly
ic relapse, the question arises of whether yes. This was a marital couple where the
they operate in a similar manner prior to the husband was the patient. They received
first episode. It is logically inadmissable to marital therapy from the clinical psychia-
extrapolate our findings backward in time trist in parallel with our sessions of family
to before the first attack of illness since this therapy. It is possible that this diversifica-
itself may dramatically alter relatives' at- tion of effort weakened the potency of the
titudes. However, evidence exists linking two sets of therapists, and more would have
one emotional attitude we found to be in- been achieved with a single set.
fluential, with maternal overprotectiveness The other two families shared a number
antedating the onset of schizophrenia. This of features in common: they both had multi-
evidence, which derives from child guid- ple problems, the patient was a single girl in
ance clinic studies, was reviewed by Hirsch both, and the key relative was a mother who
and Leff (1975) who concluded that over- was both excessively critical and overin-
protective attitudes were more commonly volved. In one family, already, referred to,
shown by mothers of children who later the patient had Turner's syndrome in addi-
develop schizophrenia than mothers of con- tion to schizophrenia, and the mother had
trol children. There is a clear link between shown overinvolved attitudes to her almost
this early overprotectiveness and an aspect from birth. In the other, the mother was Ita-
of overinvolvement, as measured in the stu- lian and spoke broken English, and it was
dies of EE. This suggests that the overpro- doubtful, in retrospect, whether she took in
tective component of overinvolvement much of what went on in the relatives'
develops very early in the child's life, and group and family sessions.
indeed we have anecdotal evidence of this In the first of these two families, the pa-
from several of our families. It is likely that tient relapsed after only 2 months at home
the long-standing nature of this component and before her mother had started to attend
of maternal overinvolvement accounts for the relatives' group. This was an unusual
the lesser degree of success we had in alter- delay and may have been symptomatic of
ing this attitude when compared with our the mother's resistance to therapy. In fact,
effect on criticism. The single dramatic dis- we continued working with the family fol-
appearance of overinvolvement was not in a lowing the patient's relapse, and after a
mother but in a wife, who would of neces- year or more there are some indications of
sity have held this attitude for a much short- change in the mother's attitudes. These will
er period of time. be assessed at the 2-year follow-up. The
The other theoretical consideration is the second of these two families, with the ita-
mechanism by which relatives' attitudes lian mother, we felt would probably have
produce a recurrence or exacerbation of resisted the efforts of the most experienced
schizophrenic symptoms in the patients. therapist. However, someone who was
Previous studies have established that the bilingual in English and Italian might well
effect of high EE relatives on patients is have breached the communication barrier.
164 J. Leff et al.
The other two practical issues are closely requires no special training and could read-
connected: which element in our package ily be introduced as part of the history tak-
was the most effective, and what should be ing. In choosing between the strategies of
taught to professionals who intend to work attempting to reduce face-to-face contact or
with the families of schizophrenic patients? to lower EE, it might be assumed that the
We cannot answer the first question fully former was the easier and less time-con-
since we did not evaluate the individual ele- suming option. Indeed, we began the trial
ments of our package, apart from the edu- with this explicit assumption. However, we
cation program. In the absence of this infor- found that a number of families were very
mation' we have to assume that the rela- reluctant to spend less time together and yet
tives' group and family sessions are of equal responded to our attempts to reduce EE. In
importance. Working with families would other families, we felt that a reduction in
appear to require a longer training than the contact only became possible when the
running of relatives' groups, but it must be emotional bonds tying them together had
appreciated that we had little experience in been loosened. As it turned out, we were
either form of therapy with families of schi- equally successful in achieving both aims so
zophrenic patients when we started and yet would recommend their joint adoption by
managed to achieve a high success rate in clinicians.
meeting our aims. We consider that part of From the beginning, we have been sensi-
the formula for success is the setting out of ble of the need to keep our interventions
clear aims from the beginning, and anyone within the scope of everyday clinical prac-
entering this area of clinical work should tice. We attach such great practical impor-
have as a target the reduction of face-to- tance to the result of our trial that we see
face contact and of critical and overin- our next task as the compilation of a train-
volved attitudes in the relatives. ing program that will make the necessary
The clinician is faced with the problem skills available to social workers, clinical
of deciding which families need this kind of psychologists, and psychiatric nurses.
approach. Unfortunately, the training re-
quired to rate EE is a long and arduous pro-
cess so that the Camberwell Family Inter- Acknowledgment. We are grateful to the consult-
ants at the Bethlem and Maudsley Hospital, the
view cannot be incorporated routinely into Southwestern Hospital, and the North Wing at St
clinical assessment. However, most high Pancras Hospital who allowed their patients to
EE families are readily identified by clin- take part in this study. Our thanks are due to Dr.
icians, even those unfamiliar with the con- Bebbington for carrying out PSE assessments on
cepts of criticism and overinvolvement. some patients and to Dr. Vaughn and Dr. Ghosh
Families with borderline levels on these sca- for conducting EE assessments on some relatives'
les are likely to be missed in clinical prac- interviews.
tice, but the clinician should be alerted to An extended version of J. Leff, L. Kuipers, R.
the possibility that relatives are high EE if Berkowitz, R. Eberlein-Vries, and D. Sturgeon,
"A Controlled Trial of Social Intervention in the
patients living with them require frequent Families of Schizophrenic Patients". British
readmissions despite prophylactic medic- Journal of Psychiatry, 1982, 141, 121-134. Copy-
ation. right 1982. The Royal College of Psychiatrists.
The determination of the degree of face- Reprinted by permission of authors and pub-
to-face contact is a simple procedure which lisher.

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Drug and sociotherapy in the aftercare of schi- Sturgeon, D., Kuipers, L., Berkowitz, R., Tur-
zophrenic patients. One-year relapse rates. pin, G., and Leff, J. (1981). Psychophysiologi-
Archives of General Psychiatry, 28, 54-64. cal responses of schizophrenic patients to high
Hogarty, G. E., Goldberg, S. C., Schooler, N. and low expressed emotion relatives. British
R., and Ulrich, R. F. (1974). Drug and socio- Journal of Psychiatry, 138,40-45.
therapy in the aftercare of schizophrenic pa- Tarrier, N., Vaughn, C. E., Lader, M. H., and
tients. II. Two-year relapse rates. Archives of Leff, J. P. (1979). Bodily reactions to people
General Psychiatry, 31, 603-608. and events in schizophrenia. Archives of Gen-
Hogarty, G. E., Schooler, N. R., Ulrich, R. F., eral Psychiatry, 36, 311-315.
Mussare, F., Ferro, P., and Herron, E. (1979). Vaughn, C. E., and Leff, J. P. (1976a). The in-
Fluphenazine and social therapy in the after- fluence of family and social factors on the
care of schizophrenic patients. Archives of course of psychiatric illness. A comparison of
General Psychiatry, 36, 1283 -1294. schizophrenic and depressed neurotic patients.
Leff, J. P. (1976). Schizophrenia and sensitivity British Journal of Psychiatry, 129, 125-127.
to the family environment. Schizophrenia Bul- Vaughn, C. E. and Leff, J. P. (1976b). The mea-
letin, 2, 566-574. surement of expressed emotion in families of
Leff, J. P. (1981). Clinical and methodological psychiatric patients. British Journal of Social
problems in interaction studies. In G. Tognoni, and Clinical Psychology, 15, 157-165.
C. Bellantuono, and M. Lader (Eds.), Epi- Wing, J. K., Cooper, J. E., and Sartorius, N.
demiological Impact of Psychotropic Drugs. (1974). Measurement and classification of psy-
Amsterdam: Elsevier. chiatric symptoms. Cambridge: Cambridge
University Press.
Appendix

Vignettes of mgh EE Families in Study


I = iDitiai assessment; F = foUow-up assessment;
C = critical comments; 0 = overinvolvement
score.

Experimental Families

Case 1 Mother I: Cll, 03; F: Cl, 02. Case 3 Wife I: C26; F: Cll.
Stepfather I: C9; F: C2.
The patient, a married man of 42, had been
The patient, a man of 23 living with mother, step- admitted six times before the current episode of
father, and a younger brother, suffered a first at- schizophrenia. He had not been able to work in
tack of schizophrenia. Mother had always seen the preceding 18 months. There were three chil-
him as the weaker of her two sons and appeared dren, with the eldest of whom, a daughter, he had
to have been overinvolved with him virtually had an incestuous relationship some years previ-
from birth. He slept in her bed till the age of 15. ously. This had come to light and he had served a
He was discharged from the hospital to a hostel, prison sentence. His wife was very intolerant of
but left after a few weeks to return home. How- his handicaps and extremely critical of his inabili-
ever, he attended a day hospital so that contact ty to playa man's role in the family. She used the
remained low. Family sessions included his par- group to vent a great deal of anger. Family ses-
ents and brother and focused on the marital rela- sions were held, sometimes including the chil-
tionship, which was initially poor, but improved. dren, but our attempts to persuade patient and
The patient was free of psychotic symptoms on wife to spend less time together were unsuccess-
discharge and remained so throughout the 9 ful. Although she welcomed the opportunity to
months. go out in the evening, he both refused to ac-
company her and made her feel guilty about leav-
ing him. At follow-up, her criticism had consid-
Case 2 Husband I: C9; F: CO. erably abated, although not below the crucial
The patient, a married woman of 53, experienced level, and they remained in high contact. Never-
a second episode of schizophrenia. Her husband, theless, he remained free of psychotic symptoms,
a retired professional and an intelligent, emo- although he continued to exhibit a significant de-
tionally inhibited man, was extremely intolerant gree of depression.
of her irrationality when she was ill. He attended
the group regularly, and in addition we conduct-
Case 4 Wife I: C7, 01; F: C2, 01.
ed joint sessions in the home, but we were never
able to explore the emotional roots of his in- The patient, a married man of 47, was admitted
tolerance. Nevertheless, his critical attitude had on the second occasion for an episode of paranoid
disappeared at follow-up, and his wife remained schizophrenia. He believed that the neighbors
free of all symptoms. They continued to be in downstairs were interfering with his apartment in
high contact despite her joining day classes, and various ways, a belief that his wife shared, thus
his taking up a part-time teaching job. exhibiting folie Ii deux. He had retired from his
Appendix 167
job as a caterer 3 years earlier on account of phy- Case 7 Mother I: C16, 01; F: C3, 02.
sical ill health. One conjoint marital session was
held, following which his wife attended the group The patient, a divorced woman of 42, lived with
on a single occasion, but as no other relatives ar- her elderly mother and was admitted for the first
rived that time, she was given an individual ses- time with an episode of schizophrenia. A younger
sion by the psychologist. She refused to come to sister had suffered from schizophrenia for many
the group again. The patient lost his paranoid de- years and had eventually committed suicide. The
lusions while in the hospital, and his wife's abnor- patient slept in the same bedroom as her mother,
mal beliefs also disappered. He remained well who was very critical of her. The patient was also
and at follow-up was found to be in low contact as physically disabled by chronic bronchitis and was
he had increased the time spent going out on his unable to work. Her mother attended the group
own. regularly, and sessions were also held in the
home. In particular, we attempted to persuade
the patient to move into a bedroom of her own
and to influence her mother to allow her to do
Case 5 Wife I: C8; F: C9. more for herself in the home. We made efforts to
The patient, a married man of 55, was admitted get the patient to attend a day center, but she was
for the first time with an acute and florid attack of very resistant to this, so instead we arranged for
schizophrenia. He had been unemployed for 3 her to come to the hospital daily as a day patient.
years having lost his job as a chauffeur through a At follow-up, she was spending much less time
drinking and driving offence. He had married his with her mother, although still in high contact.
wife when she was pregnant with another man's Her mother had become much less critical,
child, and they had had four children of their though was slightly more overinvolved and they
own. His wife was critical of him and showed little still slept in the same room. At discharge, the
warmth. She attended the group regularly, and patient was hearing voices continuously despite a
we held several conjoint marital sessions, but at high dose of a phenothiazine. The voices gradual-
follow-up her critical attitudes were unaltered ly attenuated over the course of 9 months and
and the marital relationship appeared to be were much less insistent and frequent at follow-
unchanged. However, the patient had taken on a up.
job as a security guard and because of the shifts he
worked was in low contact for 5 of every 6 weeks.
He remained free of psychotic symptoms
throughout the 9 months.

Case 6 Wife I: C3, 04; F: C1, 00. Case 8 Husband I: C26; F: C15.
The patient, a married man of 56, was admitted The patient, a married woman of 44, was admit-
for the tenth time with a psychotic illness. In the ted for the sixth time with an attack of schizo-
past, his diagnosis had varied between schizo- phrenia. She and her husband ran a hotel and
phrenia, mania, and schizoaffective psychosis. both abused alcohol. However, there was no
On this occasion, he had first-rank symptoms as doubt of the schizophrenic nature of her illness.
well as grandiose delusions and was diagnosed by He was exceedingly critical of her, and they often
CATEGO as S+. His wife had been a social had physical fights. Because of their work, the
worker and gave up her job on marrying him 6 husband could not attend the group, so instead
years previously. It was evident that she treated regular conjoint marital sessions were arranged
him as though he was her client, and this was re- to fit in with the couple's working hours. These
flected in her overinvolvement with him. He had were conducted by a female research psycholo-
given up his job as a commercial artist 7 years gist and a male staff social worker. After a while,
previously and did clerical work part-time. His it was decided that each therapist would see the
wife attended the group regularly, and in addi- same-sex client on an individual basis in place of
tion, we held one conjoint marital session in the joint sessions. The couple owned a house in
which the patient's feelings of inadequacy and his addition to living in the hotel and were encour-
wife's need to protect him were explored. This aged to spend more time in their house, where
appeared to have a significant effect as shortly they tended to occupy separate rooms. As a con-
afterward she returned to full-time work. He con- sequence, at follow-up they were in low contact.
tinued to work part-time at home and remained The husband's criticism had abated considerably
in high contact with his wife, but at follow-up her but was still well above the safe level. The patient
overinvolvement had completely dissipated. The had no recurrence of symptoms during the 9
patient remained well. months.
168 Appendix
Case 9 Mother I: C41, 04; F: Cll, 03. spoke broken English, while the patient was
Father - low contact. bilingual. Her father, a caretaker, spent long
hours away from the home. The patient was ad-
The patient, a youth of 20, lived with his parents mitted for the third time with an acute episode of
and two siblings. His father, an engineer, worked schizophrenia. Her mother had few friends, took
long hours, and they spent little time together. the patient with her wherever she went, and
He was admitted with a first episode of schizo- clearly treated her as her principal companion.
phrenia and was markedly overactive, running They slept in the same bed, while the father was
away from the hospital on several occasions. His banished to another room. Her mother joined the
mother was one of the most critical relatives in group and several family sessions were held, in-
the study and was also highly overinvolved. She cluding the brother. Communication in these ses-
attended the group regularly, and we also held sions were held, including the brother. Com-
several sessions with the patient and both his munication in these sessions was very disrupted,
parents. Although he recovered from the acute and we put a lot of effort into clarifying it. It pro-
episode, the patient continued to complain of ved very difficult to engage her father in the
apathy and anhedonia throughout the follow-up therapeutic program. At follow-up, the mother's
period. He improved very slowly, began to at- attitudes were unaltered, and she remained in
tend the hospital as a day patient, and started high contact with the patient. Nevertheless, there
playing squash and taking up the piano again. At had been no relapse.
follow-up, his mother showed a reduction in both
elements of EE, but not below the crucial levels.
However, the patient was found to be in low con- Case U Mother I: C27; F: C3, 02.
tact with her, as well as with his father, and suf- The patient, a single woman of 41, lived with her
fered no return of the florid symptoms of his ill- mother. She was admitted for the second time
ness. with an episode of schizophrenia. The patient's
mother was extremely critical of her, but she
spent all her leisure time with her. Her mother
Case 10 Mother I: C15, 05; F: C14, 03. received the education program and was a regu-
The patient, a woman of 25, lived with her lar attender at the group. The group terminated
mother and mother's boyfriend, her father hav- before the follow-up was due, and a research psy-
ing committed suicide in a psychiatric institution. chologist saw the mother and daughter every 2
The patient suffered from Turner's syndrome re- weeks for the rest of the follow-up period. This
sulting in dwarfism, as well as schizophrenia. She patient was in the hospital for nearly 1 year and
was admitted for the third time. Her mother had appeared at times to be at risk of becoming in-
always been overprotective, and this had been stitutionalized. At discharge, she was free from
intensified with the advent of schizophrenia. Her florid symptoms but showed blunting of affect
mother was also excessively critical. It proved dif- and no spontaneous speech. She had been work-
ficult to get the mother to attend the group and ing prior to her admission, but was too handi-
before she did so, the patient relapsed with a re- capped to resume work and attended a day hospi-
currence of florid symptoms during a weekend tal three times a week and a day center twice a
together at a holiday caravan. This occurred 2 week. Much of the therapeutic work was aimed at
months after discharge and was the only relapse enabling the patient to become more active, to
in the experimental group. Following this, her get up in the morning at a reasonable hour, and to
mother began to attend the group regularly, and do some household tasks. In addition, our aim
we held several family sessions. At follow-up, the was to help the mother to encourage her daughter
mother's criticism was unchanged, though she in these activities and to persevere with her ef-
was considerably less overinvolved. However, forts. At the 9-month follow-up, the mother sho-
she and the patient were still in high contact. wed very little criticism although she was a little
more emotionally overinvolved. The patient ex-
perienced no recurrence of florid symptoms dur-
Case 11 Mother I: C6, 04; F: C7, 04. ing the 9-month follow-up period. Her affect re-
Father - low contact. mained rather restricted, but she showed much
more spontaneous speech, had resumed some
The patient, a woman of 23, lived with her par- hobbies such as knitting, helped with chores, and
ents and a brother. Her mother was Italian and in particular kept her own room clean and tidy.
Appendix 169
Control Families

Case 1 Father I: C8; F: C14. Case 5 Sister I: C6; F: C2.


Mother -low EE. The patient, a woman of24, was the only subject
The patient, a man of 29, lived with his parents. in this study living with a sibling, her older sister.
He was unemployed and was in high contact with She was admitted for the third time with an epi-
his father, who had retired from his job as a te- sode of schizophrenia, which completely re-
lephonist. The patient was admitted for the sixth solved. Her sister was given no professional help,
time with an episode of schizophrenia. On dis- but despite this was much less critical when seen
charge, he continued to hear voices, which per- at follow-up. They remained in high contact, and
sisted unchanged throughout the follow-up per- the patient experienced no return of her symp-
iod. No therapeutic work was done with the par- toms.
ents, and the father's level of criticism had risen
at follow-up.
Case 6 Mother I: C13, 01; F: refused.
Father I: C38; F: C32.
Case 2 Mother I: 03; F: 04.
The patient, a woman of 24, lived with her par-
Father - low contact. ents and siblings. Both parents were highly criti-
The patient, a man of 30, lived with his parents. cal of her, particularly her father. She was admit-
He worked as a sales assistant but was in high ted for the second time with schizophrenia and
contact with his mother as they spent all their lei- responded well to treatment. She met and mar-
sure time together. His mother was overinvolved ried another patient while in the hospital and
with him, though not at all critical. He developed went to live with him on discharge. However, this
a first attack of schizophrenia from which he re- was not a success, and after a while she returned
covered completely. No therapeutic work was home. After a few days, her father had a furious
done with his parents, and he suffered a return of row with her and ordered her to sleep in a shed in
his psychotic symptoms a few months later. At the garden. Sevcral days later, she suffered a
follow-up, his mother's overinvolvement had return of auditory hallucinations.
somewhat increased.
Case 7 Mother I: C5, 05; F: C?, 03.
Case 3 Wife I: C6; F: CO. Father - low contact.
The patient, a man of 33, lived with his wife and The patient, a young woman of 21, lived with her
two children. He was admitted for a second time parents. Her father, a postman, lived virtually a
with an episode of schizophrenia. His wife's crit- separate life from the rest of the family and was in
icism was just over the threshold. He recovered low contact with the patient. She was admitted
completely with treatment and went back to his with a first attack of schizophrenia from which
job as a porter. The wife received no professional she made a slow but complete recovery. When
help, but when assessed at follow-up was com- her mother was seen for an EE assessment, it
pletely uncritical of her husband. They continued became clear that she was psychiatrically ill and
to be in high contact and he remained well. she was referred to a psychiatrist. He decided that
she was also suffering from schizophrenia, which
had not been previously diagnosed. The mother
Case 4 Husband I: C8; F: unobtainable. was treated for this as an outpatient with a
The patient, a woman of 48, lived with her hus- neuroleptic drug, but her attitudes to her
band and the youngest oftheir eight children. She daughter were not focused on. The patient suf-
was admitted with a second attack of schizophre- fered a recurrence of schizophrenia several
nia, from which she made a full recovery. Her weeks after leaving the hospital. At follow-up,
husband was quite critical of her and had left her mother refused to allow the interview to be
home for short periods in the past. Several recorded so that critical comments could not be
months after her discharge, he left her again, but assessed. However, her overinvolvement with
this time did not return. Some weeks later, she her daughter was still found to be high, and they
suffered a recurrence of florid symptoms and was remained in high contact.
readmitted.
170 Appendix
Case 8 Mother I: 05; F: 05. Case 10 Mother I: 04; F: 03.
Father - low contact.
The patient, a man of 31, lived with his mother.
He had never had a girlfriend, and he and his The patient, a youth of 20, lived with both par-
mother appeared to be totally absorbed in each ents. He had never had a girlfriend and spent
other. He was admitted for the first time with an much of his leisure time with his mother. He wor-
episode of schizophrenia, from which he made a ked as a post-office clerk and returned to this job
full recovery. He had been unemployed for 1 year on discharge. His admission was for a first epi-
before his admission, and he remained without a sode of schizophrenia, and he made a full recov-
job during the follow-up period. He was reluctant ery. No professional help was offered the
to attend a day hospital and spent virtually the mother, whose overinvolvement was a little less
whole day confined in their apartment with his at follow-up, but still above the crucial level.
mother. He experienced a return of his symptoms However, the patient had developed leisure acti-
a few months after discharge. At follow-up, the vities of his own and was in low contact with his
mother's overinvolvement was just as intense, mother. He remained well.
and they were in high contact. A single family in-
terview had been held to persuade him to attend
a day hospital. Case 11 Wife I: C8, 02; F: C8, 04.
The patient, a man aged 40, lived with his wife
Case 9 Husband I: C7, 04; F: refused. and two children. She was quite critical and
somewhat overinvolved. He was admitted with a
The patient, a woman aged 37, lived with her hus- second episode of schizophrenia, from which he
band and three children. He was quite critical of made an incomplete recovery, continuing to har-
her, but also overinvolved, showing a degree of bor a number of delusions when discharged. A
morbid jealousy. She was admitted for the second social worker saw his wife at regular 2-weekly
time with schizophrenia and during her admis- intervals throughout the 9 months, but at follow-
sion asserted that she had had a sexual encounter up her overinvolvement had actually intensified.
with another patient. The truth of this was un- However, the patient had reduced his contact
certain, but it exacerbated her husband's jeal- with her by retiring to his room, and his conditon
ousy, and he could not get it out of his mind. He did not worsen during the follow-up period.
became clinically depressed and received outpa-
tient treatment over the course of 2 months. On
discharge, the patient was still hearing voices, but Case 12 Husband I: C14, 03; F: C8, 03.
these gradually became less insistent, and she did The patient, a woman of26, was admitted for the
not suffer any exacerbation of her symptoms over second time with an episode of schizophrenia.
the 9 months. Her husband refused a follow-up Unlike the first attack, this one immediately fol-
assessment, but in a brief interview the impres- lowed the birth of a child and had a prominent
sion was gained that his attitudes were un- depressive component. Her husband was both
changed. highly critical and overinvolved. Her illness ran a
protracted course, but she finally became free of
symptoms and went home. Her husband received
no professional help, and at follow-up was still
excessively critical and overinvolved. The patient
suffered a relapse with the same mixture of schiz-
ophrenic and depressive symptoms several
months after discharge.
14. Behavioral Family Therapy for Schizophrenia:
Clinical, Social, Family, and Economic Benefits
I. R. H. Falloon

Introduction
Behavioral family therapy represents a focus on manifest weaknesses. It is assumed
clear departure from the focus on "ab- that in very situation each family member is
normal" family interaction patterns that has doing his or her best to cope with the stres-
played a prominent role in the psycho- sors that they are experiencing. Their abil-
dynamic and non behavioral family theories ity to achieve ideal solutions and goals is
of schizophrenia. Research and clinical limited by a broad range of personal and en-
practice, especially with psychodynamic vironmental constraint, such as intelli-
and systemic methods, have sought to gence, past experience, education, social
examine the detrimental effects of family learning, interpersonal role patterns, and
transactions upon the family member who finances. It is assumed that they will en-
is experiencing the symptoms of schizo- deavor to fashion the most effective re-
phrenia (Fromm-Reichmann, 1948; Lidz, sponses from all the resources within their
Fleck, and Cornelison, 1965; Jackson and group. However, it is recognized that under
Weakland, 1960; Wynne, Ryckoff, Day, the added strain of having one (or more)
and Hirsch, 1958). Despite formulations to family member(s) suffering from a major
the contrary, the paradoxical approaches of illness that the capacity for efficient prob-
the Milan group (Selvini-Palazzoli, Ce- lem solving will be eroded, sometimes to
chin, Prata, and Boscolo, 1978) have tend- the point where other individuals in the
ed to instigate change through the parents family may decompensate and become phy-
of disturbed index patients, indirectly im- sically or mentally ill under the burden.
plicating their behavior as detrimental. On This is particularly so when the symptoms
the other hand, the behavioral family thera- are persistent and disruptive to the usual
py approach proposes that the family is the pattern of family interaction. Thus, it may
basic unit for the promotion of the healthy not be sufficient for the family of a chron-
functioning of all its members, and it is a ically ill person to function as an average
crucial determinant in the recovery and re- problem-solving unit; indeed, they may
habilitation of those suffering from illness. need to achieve much greater than "nor-
This natural care giving function of families mal" family functioning to preserve their
is considered to be the greatest resource own health as well as restore the health of
available to the mental health services. the sick member. This paradigm of effective
For this reason, the behavioral family problem solving in families alters, in a fun-
therapy approach seeks first to evaluate the damental fashion, the way we assess family
healthy elements of family communication functioning and subsequently formulate
in solving everyday problems before assist- our therapeutic interventions. The goal is
ing the family to enhance their problem- not merely to ameliorate symptoms through
solving efficiency. Minimal attention is reducing stress in the environment, but also
accorded to patently ineffective problem- the enhance the functioning of each mem-
solving strategies. The aim is to build upon ber of the family unit.
pre-existing family strenghts, rather than
172 I. R. H. Falloon
Behavioral Analysis of Family Functioning
The first step in behavioral family therapy This is the first time the family is brought
involves an assessment of the strenghts and together as a group. Previous assessments
weaknesses of the family as a problem-solv- of individual family members may have re-
ing unit. Particular note is made of the pre- vealed reports of problem-solving efforts,
cise manner in which they tackle the prob- but such reports provide only a sketchy
lems of everyday life together, as well as view of family discussions from highly sub-
their responses to significant life events. jective viewpoints. We have employed
Life problems include the personal goals of several methods to obtain naturalistic ob-
individual family members. servation of family problem-solving behav-
Initially, family members are interviewed ior. Perhaps the best has been obtained
individually to establish their unique assets from observing the family in their home.
and deficits, their personal life goals, and Occasionally this is not feasible, and clinic-
the assistance they obtain from other family based analogues have been used. It is im-
members in their attempts to achieve these portant to realize that families may not pro-
goals. Their feelings and attitudes toward vide valid evidence of their functioning
other family members are discussed. The within the constraints of the clinic and that
Camberwell Family Interview (CFI) provi- at least one home visit is crucial in their as-
des a useful adjunct to this individual analy- sesment. The problem-solving test that we
sis, although in its abbreviated form have found most useful involves carefully
(Vaughn and Leff, 1976a) it focuses on re- choosing a "hot issue" that concerns all
lationships with the index family member family members and leaving them to at-
and his or her behavioral disturbance. tempt to resolve the problem within a 10-
The second step in behavioral analysis of min period. This time interval is often too
a family unit involves an assessment of the brief to allow detailed planning to be achie-
relationships between the various goals and ved but provides a surprisingly good insight
problems of individual family members. It into the structure and strategies the families
is clear that the aspirations of individual employ in their discussions. The strengths
family members may conflict at times with and weaknesses of the family's communica-
the wishes and values of other family mem- tion and problem-solving skills can be relia-
bers. An insecure mother may not want her bly coded for clinical and research analysis.
son or daughter to leave her and go to work Once these steps have been undertaken,
or a day center every day. often over several weeks, and up to 20 h of
Strictly religious parents may be upset by intensive assessment, the behavioral family
social activities that involve drinking or therapist is in a position to formulate a
sexual contact. Such conflicts with individ- management plan that is uniquely structur-
uals' goals for themselves and one another ed to enhance the problem-solving efficien-
may undermine progress unless they can be cy of each family unit. The current efforts of
resolved by effective problem solving. families to cope with their problems and
Seemingly positive changes, from a thera- achieve their goals are documented, and
pist's perspective, may be perceived dif- these serve as the basis upon which to con-
ferently by the family as a whole. It is, struct increasingly effective problem solv-
therefore, crucial that the therapist can for- ing. This base line behavioral analysis is
see these potential problems at the onset of merely the initial phase of the program, and
intervention and can help the family to seek throughout the course of treatment similar
creative solutions at an early stage. This assessment of family functioning continues,
analysis of how the family fits together as a enabling strategies to be modified as new
system is described as functional analysis by information is gathered. The therapist is
behavioral therapists. It has much in com- constantly addressing his or her own prob-
mon with the systemic analysis of ap- lem of "How can I assist this family to con-
proaches based on systems theory. duct their own problem-solving functions
The third step involves observation of the more efficiently?"
family having a problem-solving discussion.
Behavioral Family Therapy for Schizophrenia 173
Treatment Program
The most important component of the tre- continuing drug treatment that is carefully
atment program is the behavioral analysis. monitored throughout. Index patients play
The initial and continuous pinpointing of a crucial role in this education. They are en-
specific deficits of family problem solving couraged to describe their own experiences
enables the therapist to assist the family to of schizophrenia and its management to
achieve gradually more fluent strategies for their families. Usually, this is the first oc-
coping with the wide variety of difficulties casion on which the nature of the patient's
they encounter, while at the same time con- symptoms has been discussed among the
tinuing to promote their personal life goals. family. The patient assumes the "expert"
Many families show considerable compe- role, although at times other family mem-
tence in problem solving, but through a lack bers may report similar episodes of schizo-
of understanding of the nature of schizo- phrenic symptoms in the past or even the
phrenia may seek solutions that provoke present. These sessions are delayed until
excessive stress for the index patient. Other the index patient is stabilized after an acute
families may have difficulties conducting a episode and is usually able to discuss his ex-
calm discussion within their family group. periences in an objective manner.
One person may assume dictatorial control A questionnaire is administered before
and prevent the flow of ideas and sugges- and after these initial sessions to assess the
tions from others; another may not listen to amount of information acquired and to note
what others are saying; in many cases, fam- areas where further education may be ne-
ilies do not sit down in a relaxed setting, cessary. Prior to this education, half of all
free from distractions to discuss important patients and family members knew the di-
issues; still other families who reach agree- agnosis of the patient's condition; after-
ment on what appears to be the optimal so- ward, 95% agreed with the primary diagno-
lution to resolving a problem fail to imple- sis of schizophrenia. A 50% increase in
ment that solution owing to inadequate scores on a multiple-choice questionnaire
planning. There are no familial defects that about schizophrenia has been observed
are specific to schizophrenia. However, the consistently (McGill, Falloon, Boyd, and
unusual nature of the disorder and the Wood-Siverio, 1983).
stress that ensues for patients and their
caregivers tend to provoke inefficiencies of
Communication Training
problem solving.
The major interventions employed in the At times of crisis, ineffective patterns of
behavioral family therapy program can be communication substantially impede cop-
divided into four broad categories: ing efforts and contribute to the stress that
1. Education about schizophrenia may trigger exacerbations of schizophrenia.
2. Communication skills training Effective communication is the basis for ef-
3. Problem-solving skills training ficient problem solving. The major com-
4. Behavioral strategies for specific prob- ponents of family communication that are
lems assessed involve the ability to listen em-
pathically to one another when discussing
problem issues, mutual communication of
Education About Schizophrenia
positive and negative feelings, and making
Although the mutual sharing of information constructive requests for behavior change.
about the nature, course, and treatment of The nonverbal and verbal components of
schizophrenia is a continuous process, two interpersonal communication are addres-
sessions at the onset of family therapy are sed, particularly where major deficits
devoted to discussion about the diagnosis, detract from the clarity of such expression.
etiology, management, course, and drug Improved communication is shaped
and psychosocial treatment of the disorder. through skills-training procedures, where-
These initial sessions provide a rationale for by brief segments of interaction are re-
the subsequent family therapy and for the hearsed repeatedly with instructions,
174 I. R. H. Falloon
modeling, social reinforcement, and per- 2. List Alternative Solutions. Once the
formance feedback from the therapist and problem has been specified, a brain-storm-
family members. Homework assignments ing approach is used to generate a list of po-
are employed so that family members con- tential solutions. Discussion about the rela-
tinue to practice these skills outside the tive merits of each solution is postponed,
therapy sessions. and both "good" and "bad" ideas are re-
No specific attempts are made to prevent corded. Reticent family members are en-
family members from expressing criticism, couraged to express their thoughts, and
hostility, rejection, or overinvolved com- every idea is acknowledged by adding it to
munication in their discussions. These pat- the list.
terns of expression, directed toward the in- 3. Discuss Merits of Each Solution. Each
dex patient, have been considered predic- solution is discussed in tum. The advan-
tive of symptom exacerbations (Vaughn tages and disadvantages of each are high-
and Leff, 1976b). Nevertheless, effective lighted.
training of modes of communicating posi- 4. Choose the Optimal Solution. The fam-
tive and negative feelings is likely to reduce ily chooses that solution (or combination of
the frequency with which these potentially solutions) that best fits the needs of the
destructive comments are made. Families problem and the resources of the family.
are encouraged to express their feelings of 5. Plan How to Implement the Solution.
anger, frustration, and guilt within a con- Detailed plans are drawn up to map out the
structive problem-solving framework. In steps through which the solution will be im-
this way, their negative expressions become plemented. Strategies for ensuring that the
the initial steps in identifying and resolving solution is implemented smoothly are de-
difficult problems, thereby relieving stress vised. Major roadblocks are anticipated,
in the family. and ways of coping with these and other im-
portant consequences are discussed. At
Problem-Solving Training
times, families may rehearse the steps
among themselves in a dry run; often
Families are encouraged to adopt a struc- merely talking through the procedures step-
tured approach to their problem-solving by-step is sufficient.
discussions. This involves arranging specific 6. Review All Efforts. Any genuine at-
times when the whole family can meet, free tempt to implement the plan is acknowl-
of distractions, to discuss important issues. edged and praised, even if a successful out-
The frequency of such family meetings, come was not achieved. The family is en-
their duration, and the choice of topic for couraged to review their efforts and to use
discussion is left to the discretion of the all knowledge gained to construct a more
family. However, they are advised to meet effective plan. The notion that successful
at least once a week, to limit the time spent, problem solving requires persistent and re-
and to choose relatively straightforward peated efforts is clearly instilled.
problem issues for their initial meetings. The therapy sessions enable families to
The family therapy sessions examine the practice their problem solving under the
progress of their family discussions and pro- supportive guidance of the therapist. Initi-
vide a workshop for enhancing their ef- ally, and at times of crisis, he or she may
fectiveness. A six-step model of problem need to provide clear direction for the fami-
solving is advocated as a guide for the fami- ly. Guidesheets that list all the steps of
ly meetings. The six steps include: problem solving are used during the ses-
1. Identify a Specific Problem. This step sions and in family discussions at home.
entails active listening to each person's de- One family member "chairs" the discus-
scription of the problem, seeking clarifica- sion, recording notes on the sheets of each
tion when necessary, and avoiding giving problem-solving step. As soon as the family
premature advice or reassurance. The aim begins to master the approach, therapist
is to be able to specify the problem in clear involvement is withdrawn.
operational terms that are readily under-
stood by all family members.
Behavioral Family Therapy for Schizophrenia 175
Behavioral Strategies for Specific Problems setting, and skill training.
The burden of management of severe,
Few families have an adequate repertoire of persistently handicapped individuals can be
coping behavior to manage all the problems substantially reduced when families can
that arise in the course of schizophrenia. learn to make effective use of supportive
Although the problem-solving structure persons and agencies in their social net-
helps facilitate creative resolution of diffi- works.
cult problems, there are times when ad- At all times, the therapist remains clearly
ditional professional assistance may be em- aware that his role is that of a facilitator of
ployed. Behavioral strategies that have family problem solving and that the goal of
been validated in research studies to assist therapy is to enhance the family's own ef-
with symptoms of anxiety, depression, ob- forts in the most efficient manner possible.
sessive-compulsive disorders, persistent de- Thus, additional behavioral strategies are
lusions or hallucinations, medication com- not introduced until the families have failed
pliance, or enhancing social and sexual inter- to achieve a satisfactory outcome with their
action are taught within the family prob- own attempted strategies.
lem-solving context. In addition to teaching A detailed manual of the behavioral
methods of dealing more efficiently with family therapy methods that have been de-
symptomatic states, families may learn a veloped for the community care of schizo-
broad range of general management skills, phrenia are provided in Family Care of
such as operant reinforcement strategies, Schizophrenia (Falloon, Boyd, and McGill,
contingency contracting, role playing limit 1984).

Controlled Outcome Study


To assess the efficacy of behavioral family The initial phase of treatment in the study
therapy as the core component of a family involved weekly sessions for 3 months,
management program for schizophrenia a tapering to biweekly sessions until 9
controlled outcome study was designed months, when once-monthly sessions were
(Falloon, Boyd, McGill, Razani, Moss, and conducted until the 2-year point. A total of
Gilderman, 1982; Falloon, 1985). It was not 40 sessions were provided in this manner
considered feasible to compare the pro- over the 2 years.
gram with a control treatment of drug ther- Therapists were assigned a similar num-
apy alone because almost every patient with ber of cases in each condition. They were
schizophrenia who attended the psychiatric available to provide additional sessions at
outpatient service on this basis tended to all times throughout the study and covered
drop out unless more extensive therapeutic for emergency calls on a 24-h-a-day basis.
contact was established. The most appro- Case management by the same therapist
priate comparison appeared to be a patient- was continued throughout any periods of
oriented management program that pro- hospital admission, day treatment, or resi-
vided a similar level of intensive support, dential care.
with optimal medication, comprehensive An extensive battery of dependent mea-
care management, and crisis intervention, sures of clinical, social, and family morbi-
including extensive family support, but dity were administered at base line and 3,9,
without the specific focus on enhancing and 24 months. In addition, monthly ratings
family problem-solving functions. of clinical factors were made throughout
The study involved the random assign- the study. Ongoing data regarding life
ment of 39 index patients and their families events and family coping were collected in
to either family therapy of individual- biweekly interviews with family members.
oriented therapy after they had been stabi- Information of potential relevance to the
lized on optimal doses of medication after monetary costs and benefits of treatment
an acute episode of schizophrenia. was recorded throughout the study.
176 I. R. H. Falloon
Patient Selection severe side effects and the availability of
laboratory assay of plasma levels, chlor-
A syndrome diagnosis of schizophrenia or
promazine was our drug of choice. Poor
delusional psychosis according to PSEI
compliance with oral preparations neces-
CATEGO criteria (Wing, Cooper, and Sar-
sitated the use of long-acting intramuscular
torius, 1974) was an initial requirement for
fluphenazine decanoate at times. Where
selection. Most patients had symptoms of
chlorpromazine was poorly tolerated, flu-
"nuclear" schizophrenia, indicating the
phenazine hydrochloride, haloperidol, and
presence of one or more of Schneider's
thiothixene were used.
first-rank symptoms. One-third had expe-
Pharmacotherapy was provided by two
rienced their first episode of schizophrenia
psychiatrists and a clinical pharmacist at
prior to entry to the study. Another one-
monthly clinic appointments. A research
third were long-standing cases. nurse collected blood samples for plasma
Age was restricted to between 18 and 45
assays. The pharmacotherapists remained
years, and patients were required to be liv- blind to the psychosocial treatments pa-
ing with (or in close daily contact with) at
tients received and conducted monthly clin-
least one natural parent. ical assessments. On the basis of these as-
At least one member of the family house-
sessments, they continuously sought to
hold was required to display high levels of lower the dosage of neuroleptics to provide
expressed emotion (EE) in the Camberwell the minimal dose that was sufficient to pre-
Family Interview or to display other clear vent the exacerbation of symptoms of schiz-
evidence of extreme family tension where ophrenia. When signs of imminent de-
high EE was absent. terioration appeared, the pharmacothera-
Three patients withdrew from treatment pists increased the doses according to need.
prior to the end of the 1st month leaving 18 Four 1-h sessions of rehabilitation coun-
in each condition. These two randomly as- seling were provided for each patient by an
signed groups were well matched on socio- experienced rehabilitation counselor. A
demographic and clinical variables. One range of vocational and psychosocial re-
further patient withdrew after 10 months, habilitation programs was made available
but continued aftercare in a neighborhood to patients in both conditions. Once again,
clinic and was reassessed after 2 years. the counselor was blind to the treatment as-
Treatment Conditions
signment.
Family therapy sessions during the first 9
Certain aspects of treatment were identical months were conducted in the patients'
for all patients, regardless of the treatment homes. Individual sessions were usually
condition. Special efforts were made to conducted in the clinic. All missed sessions
maintain patients on optimal doses of were rescheduled so that each patient re-
neuroleptic medication throughout the 2- ceived the same minimal amount of thera-
year program. Owing to its relative lack of pist contact.

Results
Thirty-six patients (18 in each condition) exacerbations of psychopathology in each
completed the initial 9 months of intensive treatment condition during the first 9
management. In a few cases, pharmaco- months of management: a total of 40 epi-
therapy was not optimal for periods, but in sodes in the family condition and 43 with in-
every case this issue was resolved, obviating dividual therapy. However, of the 18 epi-
the need for withdrawal of cases from the sodes of schizophrenia experienced with
data analysis. family management only, 3 were consider-
ed of major significance. Family cases had
10 further major episodes of nonschizo-
Clinical Morbidity
phrenic symptoms, thereby totaling 13
Patients experienced a similar number of major exacerbations. This contrasted with
Behavioral Family Therapy for Schizophrenia 177

i
130 DAYS

120 Other disorders


Anxiety
:: Depression
100 Schizophrenia

80

60

40

20
Fig. 1. Exacerbations of all symp-
toms (0-9 months).
Individual Family
management management

29 major episodes in the individual condi- parison between the coefficients of varia-
tion, 21 of which involved florid schizophre- tion of the total BPRS scores of each patient
nia . Furthermore , the duration ofthe major over the first 9 months. Family cases sho-
episodes that occurred in the family mana- wed significantly lower coefficients of varia-
gement averaged less than half that of indi- tion than individual cases (P < 0.009).
vidual management: 30 days vs 69. To date, the focus of our assessment has
Figure 1 summarizes the differences in been on florid symptoms. It is possible that
psychopathology between the two condi- the lowered morbidity associated with fam-
tions. Individual management maintained ily management was accomplished at the
symptom stability about half the time , expense of an increase in the deficit , or neg-
whereas family management cases remain- ative, symptoms of schizophrenia. This did
ed stable for about 80% of the time. These not appear to occur. Indeed, there was a
trends were maintained during the less in- trend for deficit symptoms to be reduced
tensive follow-up phase. more with family management. The BPRS
These clinical observations were sup- "withdrawal" factor, which was comprised
ported by rating scale data provided by of the items "motor retardation," "blunted
blind raters and subjected to a repeated affect," "emotional withdrawal," and
measures analysis of covariance. Monthly "grandiosity" (scaled negatively), favored
serial ratings of each patient's specific schiz- family management (P < 0.09) .
ophrenic target symptoms were signif- Qualitative blind ratings of psycho-
icantly lower for family management pathology using the PSE interview showed
(P < 0.003) throughout the 24 months (see no differences in the neurotic symptoms in
Figure 1). A similar trend was observed for the two conditions. At 9 months, ten (56%)
the BPRS "schizophrenic thought" factor of the family-managed cases were in full re-
that combined ratings of thought disturb- mission from schizophrenic compared to
ance, delusions , and hallucinations three (17%) of the individual group. At 2
(P < 0.04). The greater stability with fami- years, 12 (67%) of the family cases showed
ly management was supported by a com- no evidence of schizophrenia, with 9 (50%)
178 I. R. H. Falloon
free from any psychiatric symptoms. In con- tional performance; individual manage-
trast, 14 (83%) of the individual cases sho- ment succeeded in maintaining previous
wed persistence of schizophrenic or para- levels of functioning.
noid symptoms. The results of rating scales of social func-
Thus, there was substantial evidence that tioning showed a similar pattern, although
family management was associated with in- some deterioration of social adjustment was
creased clinical stability related to all evident during the first 9 months of individ-
sources of psychopathology. Furthermore, ual management (Falloon, McGill, Boyd,
there was a trend toward a gradual reduc- and Pederson, in press b). On the self-
tion of clinical morbidity to the extent that report measure (SAS-SR) (Weissman et
half the patients who received family man- al., 1978), an analysis of covariance, using
agement were free of any signs of mental ill- the base line scores as covariates, greater
ness at the end of 2 years. As a result of this overall social adjustment was reported with
reduction in clinical morbidity, substantial- family management (P < 0.02). Significant
ly less hospital care was required. Over the advantages were seen for the family ap-
2 years, family cases averaged 4 days in the proach on scales of leisure activity (P <
hospital and individual cases 23 days. 0.01), and family relationships (P < 0.04).
Seven items from the SBAS social per-
formance scales were examined (Platt,
Social Morbidity
Weyman, Hirsch, and Hewett, 1980).
The determinants of social functioning are These were derived from blind assessor in-
varied, not all associated with illness fac- terviews with key family members. Figure 2
tors. Both the family and individual thera- summarizes these ratings of social perform-
pies endeavored to enhance the social per- ance as well as relatives' dissatisfaction with
formance of the index patient. This was at- the impairment they observed. Small, but
tempted through direct therapist-patient significant, gains in social performance
goal setting and planning in the individual were evident in the first 9 months for family
condition and through teaching the family management cases, whereas some overall
as a whole how to use their problem-solving deterioration in social functioning was evi-
discussions to address similar issues for the dent in half the individually managed pa-
index patient as well as other family mem- tients at 9 months, with improvement
bers. occurring in the 2nd year of the program.
In the initial phase of psychosocial treat- An analysis of covariance, using the base
ment, patients with good premorbid social line scores as covariates, showed significant
adjustment and schizophrenia of recent between-group differences on the combin-
onset tended to have less difficulty re- ed social performance score at 9 and 24
establishing work and social activities. months (P < 0.02). The interaction be-
Eight patients (44%) in each management tween the groups over time was not signif-
condition were paid for work during the icant.
first 9 months. All had been working at the The relatives' dissatisfaction with social
onset of their index episode. Over 24 performance tended to parallel their re-
months, family cases were engaged in func- ports of impairment. During the first 9
tionally useful daily activities (i.e., full- or months, family management appeared to
part-time work, sheltered workshops, ed- reduce dissatisfaction in several cases
ucational or training programs) for an aver- where high levels of impairment remained.
age of 12.6 months. This compared with 7.2 This suggested that the family approach
months for individual cases. During the 24 may have assisted in instilling more tolerant
months prior to the study, patients subse- attitudes in the face of persisting handicaps.
quently assigned to family management had Individual management relatives tended
been occupied in similar constructive activ- toward less tolerant attitudes. The com-
ity for 7.0 months, and those assigned to in- bined dissatisfaction ratings over the 24
dividual management averaged 7.4 months. months significantly favored family man-
Family management was, therefore, as- agement (P < 0.0002). It was possible that
sociated with a substantial increase in func- more tolerant attitudes accounted for re-
Behavioral Family Therapy for Schizophrenia 179

• f l .·· ·
% Family management Individual management
impairment dissatisfaction
100: fimljPairm*ent dissatisfaction
Household 5
tasks
...:;:;:;:;
~... ;:;:;:;:
.. ....
,
~~~~~ ~----~~~~~

o 9 mo 0 9 mo 0 9 mo o 9 mo

100~
oil •
Leisure
activity 50 *
o 9 mo o 9 mo o 9 mo o 9 mo

Work/study
activity

o 9 mo o 9 mo o 9 mo o 9 mo

Decision
making

.u:=.-**
o 9 mo
-----Lt.~~_
0 9 mo
I
0 9 mo

Friendliness/
affection

Everyday
conversation

.~'~I
o 9 mo o 9 mo o 9 mo

100 ~
ti
Relationships ~ ......
outside family s:~
....
o 9 mo o 9 mo o 9 mo o 9 mo
indicates proportion of family-treated patients significantly less
than individually treated, p < .01
* indicates p < .05, Fisher's Exact Test

Fig. 2. Social role impairment and parental dissatisfaction with index patients' performance.
180 I. R. H. Falloon
duced reporting of social impairment. The ysis of covariance, using the base line scores
consistency of clinician, patient, and rela- as covariates, supported the superiority of
tive reports makes this unlikely, as well as the family approach (P < 0.0005).
the fact that the relatives reported continu- Benefits in terms of reductions in the clin-
ing impairment in those same areas of func- ical and social morbidity of family members
tioning where their dissatisfaction had be- other than the index patient were more dif-
come minimal. Therefore, despite the dif- ficult to demonstrate. Although a few fami-
ficulties in assessing social functioning, ly members were suffering from significant
there appeared to be good evidence for the levels of morbidity at base line, the overall
superiority of family management in reduc- levels of distress and burden did not appear
ing the social morbidity associated with to induce measurable impairments in the
schizophrenia. majority of family members. In those family
members where notable morbidity was evi-
dent, family therapy appeared more bene-
Family Morbidity
ficial. Consistent with the trend toward
We have already noted that family toler- slightly increased morbidity for individual
ance toward social deviance may have been management at 9 months, more family
increased by the family approach. Further members in this condition had significant
evidence for benefits to the family members impairment at this point.
who received behavioral family therapy in- It is important to note again that behav-
cluded significant reduction' in the distress ioral family therapy does not aim primarily
they expressed toward the patients' endur- to reduce clinical morbidity; rather, the fo-
ing clinical and social morbidity and reduc- cus is on achievement of positive functional
tion in the overall burden they associated changes. The scales used to assess change in
with having the index patient living in the this study were restricted to measuring im-
household (Falloon, Doane, and Pederson, paired functioning. As a result, positive
in press c). Figure 3 summarizes the functional goals that were achieved in the
changes in family burden in both manage- lives of our patients and families were less
ment conditions. A repeated measures anal- evident in the rating scale data. Approxi-

100 %
Family management

50

o L..-_KU.
Baseline 9 Months 24 Months

100
Individual management

Fig. 3. Percentages of families reporting mod-


erate or severe subjective burden attributed to
caring for the index patient.
Baseline 9 Months 24 Months
Behavioral Family Therapy for Schizophrenia 181
mately half the problem-solving sessions related to similar goal achievement. The
with families concerned issues relating to enhanced quality of life that was achieved
the personal goals of family members other by this approach is only dimly portrayed by
than the index patients, and the majority of our standardized measures of morbidity.
issues that concerned index patients were Nevertheless, it is clear that family-oriented

I!?
.!l1
(5
"0
"0
I/)
"0
C
tOO
'":>
I/)

=
0

.!;
I/)
1ii
0
u

Family management IndIvidual management

Fig. 4. The cost of treatment.


182 I. R. H. Falloon
management was associated with signifi- main source of added costs was the in-
cant, stable benefits in terms of clinical, creased need for crisis services, particularly
social, and family functioning and that hospital care for individual cases.
these benefits were more pronounced than Global indices of clinical, social, and
those achieved through the more usual pa- family morbidity were used to produce a 7-
tient-centered approach. point standardized index of effectiveness
that ranged from 0 = no therapeutic effects
Economic Benefits
in any area to 6 = high therapeutic effec-
tiveness in all areas. The comparative cost
A crucial limitation of many new ap- efficiency of the two management ap-
proaches to health servicves is the cost, proaches was determined by assessing the
which often exceeds that of previous ap- overall cost per unit of therapeutic effec-
proaches, and despite the advantages of im- tiveness. Individual management cases
proved effectiveness, restricts general im- averaged 2.1 units of therapeutic effective-
plementation. In this study, all direct and ness during the 1st year, at a cost of $5167
indirect costs of community management to per unit. Family cases averaged 4.0 units, at
patients, families, health, welfare, and a cost of $2220 per unit. Thus, in broad eco-
community agencies were recorded nomic terms, family management doubled
throughout the 2 years each patient was in the efficiency of the service to achieve the
the study. These costs were tabulated and goals of reduced clinical, social, and family
compared for family and individual man- morbidity. If this cost efficiency can be re-
agement (Cardin, McGill, and Falloon, plicated in everyday clinical practice, family
1985). The results of this cost analysis are management appears to be a highly attrac-
summarized in Figure 4. tive proposition for widespread deploy-
It is evident that the overall costs of the ment in the health services.
family approach were approximately 20%
less than those of individual management
during the 1st year of the study, and this Therapeutic Factors in
despite a hefty differential to account for Family Management
the added time and expense of traveling to The comprehensive nature of the manage-
the homes for family therapy sessions. The ment approaches we used did not allow us

10

8
Q)
Cil 7
u
en
Ol
c: 6
'0.
0
()
5

0 1 1-3 4-6 7-9


Follow-up
I
10-12
Fig. 5. Mean coping ratings during year 1.

Months

o Individual treatment
• Family treatment
Behavioral Family Therapy for Schizophrenia 183
to attribute the added benefits associated bidity in individual management cases.
with family management to any specific fac- It was tentatively concluded that the
tor. However, detailed data collected dur- major source of the increased efficacy of
ing the course of the study enabled us to family management probably resided in the
consider the probable effects of a number of behavioral family therapy component. Spe-
potential factors on the outcome (Falloon, cific changes resulted from the family edu-
1985). cation (McGill et al., 1983) and coummuni-
First, there was little support for the pro- cation and problem-solving training
position that random assignment had pro- (Doane, Falloon, Goldstein, and Mintz,
duced a bias that favored family man- 1985) that were the core ingredients of
agement. The two conditions were well behavioral family therapy. The coping ef-
matched on prognostic factors. Family ficiency of the family unit was specifically
management patients tended to comply enhanced by the behavioral family therapy.
more readily with medication, but skillful Figure 5 shows a highly significant linear in-
deployment of depot preparations and pro- crease in the effectivieness of the family
grams to improve adherence would seem to unit to resolve the wide range of stressful
have counteracted the potential clinical situations with which they were faced over
morbidity that may have accrued from in- the three trimesters of the intensive phase
adequate pharmacotherapy. Overall there of therapy. No such change in coping was
was a tendency for family cases to ingest evident for family units in the individual
lower amounts of neuroleptic medication condition. This increase in coping remained
than those receiving individual manage- stable after the intensive phase of behav-
ment. The impact of life events that were ioral family therapy had been completed.
not clearly associated with the patient's This improved ability to resolve stress while
condition appeared similar in both condi- achieving functional goals was attributed to
tions. Therapists favored employing family the behavioral family therapy. Further dis-
management in general, but when faced cussion of the process through which ef-
with specific patients and their families, fectiveness of the family therapy appeared
showed no differences in their attitudes to- to have been mediated is provided in Chap.
ward the patient and his assigned form of 15.
management. Conducting family therapy We have concluded that a family man-
sessions in the home on a regular basis con- agement approach that combines optimal
tributed to the very efficient delivery of this pharmacotherapy with comprehensive care
treatment, but rescheduling of missed ap- management, family education, and behav-
pointments and home sessions when neces- ioral family therapy is a cost-effective
sary enabled both conditions to receive a method of producing sustained reductions
similar amount of scheduled therapy. in the clinical, social, and family morbidity
Indeed, extra therapy time and effort was associated with schizophrenia.
required to prevent clinical and social mor-

References
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Cardin, V., McGill, C. W., and Falloon, I. R. H. kins University Press.
(1985). An economic analysis: Costs, benefits, Falloon, I. R. H., Boyd, J. L., and McGill, C. W.
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psychoanalytic psychotherapy. Psychiatry, 11, Weissman, M. M., Prusoff, B. A., Thompson,
263-273. W. D., Harding, P. S., Myers, J. K. (1978). So-
Jackson, D. D., and Weakland, J. H. (1961). cial adjustment by self-report in a community
Conjoint family therapy: Some consideration sample and in psychiatric outpatients. Journal
on theory, technique, and results. Psychiatry, of Nervous and Mental Disease, 166,317-326.
24 (2) (Supplement), 30-35. Wing, J. K., Cooper, J. E., and Sartorius, N.
Leff, J., Kuipers, L., Berkowitz, R., Eberlein- (1974). The measurement and classification of
Vries, R., and Sturgeon, D. (1982). A control- psychiatric symptoms. London: Cambridge
led trial of social intervention in the families of University Press.
schizophrenic patients. British Journal of Wynne, L. C., Ryckoff, I., Day, J., and Hirsch,
Psychiatry, 141, 121-134. S. (1958). Pseudo-mutuality in the family rela-
Lidz, T., Fleck, S., and Cornelison, A. (1965). tions of schizophrenics. Psychiatry, 21,
Schizophrenia and the family. New York: In- 205-220.
ternational Universities Press.
15. Impact of Family Intervention Programs on
Family Communication and the Short-Term
Course of Schizophrenia
M. J. Goldstein and A. M. Strachan

Introduction
Recent interest in the role of the family in Now, if there are stress-producing as-
the course of schizophrenia has focused on spects of the family environment which in-
aspects of the family environment which in- crease the likelihood of a relapse, then inter-
fluence the short-term course of the disor- vention programs designed to modify these
der once an episode of schizophrenia has aspects of the family environment should
occurred. One research strategy has been to produce a more favorable course. This has
measure aspects of the family environment been the rationale underlying four major
and then follow the natural course of the pa- studies, three of which have been com-
tient's psychiatric and social functioning. pleted (Chaps. 13,14; Goldstein, Rodnick,
This strategy has successfully demonstrated Evans, May, and Steinberg, 198) and one
that relatives' expressed emotion (EE) which is close to completion (Chap. 12).
about the patient is predictive of relapse in This chapter will provide a brief overview
both British and American samples (Chaps. of the outcome of these four studies and will
2, 8). Further, it has been demonstrated then describe in depth the impact of one in-
that this measure of emotional attitudes re- tervention program on family interactional
lates to direct observational measures of variables hypothesized to be important in
communication with the patient (Chap. 4). indexing family status: affective communi-
cation, problem solving, and coping.

Recent Family Intervention Programs and the Short-term Course


of Schizophrenia
All four studies share a number of common consisted of patients who, for the most part,
features. First, all were based on the dia- were undergoing their first lifetime episode
thesis-stress model of schizophrenia in of schizophrenia, and the period of the con-
which a biological predisposition interacts trolled trial was the 6 weeks following dis-
with environmental stressors including both charge after a very brief hospitalization. In
stressful life events and family pressures. a 2x2 design, patients were randomly as-
Secondly, all patients were kept on main- signed to one of two dose levels of in-
tenance pharmacotherapy throughout the jectable phenothiazine (moderate = 25 mg
aftercare period. The central research que- or low = 6.25 mg of fluphenazine en-
stion in these programs was whether the ad- anthate) and to the presence or absence of a
dition of a family-based therapeutic pro- crisis-oriented family therapy program.
gram to regular pharmacotherapy could re- Relapse rates were evaluated at the end of
duce the probability of relapse in the schizo- the 6-week controlled trial and at 6-month
phrenic patient. follow-up.
The first of these studies was carried out In the Leff et al. (Chap. 13) and Falloon
by Goldstein, Rodnick, Evans, May, and studies (Chapt. 14), patients were more
Steinberg at UCLA (1978). The sample chronic, received individually determined
186 M. J . Goldstein and A. M. Strachan
maintenance levels of phenothiazine drugs, Despite the wide variation in samples and
injectible in the former and oral in the lat- the format of treatment, the results of these
ter, and relatives were involved in a longer- three studies were remarkably similar. Fig-
term, family-oriented program which lasted ure 1 presents the relapse rates for these
for a minimum of 9 months. In the Leff studies, contrasting patients treated with
study, the family intervention program was and without a family-based intervention.
focused on the relatives rather than the pa- Although no final report has appeared from
tients, and the relatives were seen in the Anderson et al. study, results sum-
groups. In the Falloon study (Chap. 14), in- marized in this volume (Chap. 12) are very
dividual family therapy sessions did involve similar. Across the three studies, the re-
the patient as well as key relatives and were lapse rates for the family-treated groups are
held in the home. A common feature of the approximately one-fourth of that found in
Leff et al. (Chap. 13) and Falloon studies the groups where the relatives did not par-
(Chap. 14) was that they selected patients ticipate in a focused aftercare program.
primarily from high EE homes so that these The fact that in three of the four studies
interventions were targeted toward the most regular intramuscular neuroleptic medica-
relapse-prone patients and family units. In tion was given suggests that the family pro-
our own study, in contrast, we did not select gram added something above and beyond
on this variable, and took all consecutive insuring medication compliance. Indeed, it
patients who applied for treatment in the certainly appears that something has chan-
local community mental health center ged within the family which has markedly
whose key relatives were living in the area. altered the short-term course of the pa-
tient's disorder.

Impact of One Family Intervention Program on Family Factors


and Short-Term Course
The replicated finding that some form of familial behavior. A theoretical model that
family intervention lowers the risk for re- emphasizes the affective climate of the fam-
lapse in patients already on maintenance ily as a risk factor for relapse would receive
pharmacotherapy does not indicate what greater support if it could be shown that the
processes have been modified by the family family programs that reduce relapse do, in
program. Most family programs, tested in fact, modify this component of family life.
these controlled trials, have been com- In the report from Leff et al. (Chap. 13),
prehensive in nature, providing education there is a suggestion that this was the case,
for relatives, support for the family system, as the majority of participants in the relative
as well as specific training in altering intra- group condition did show a shift in their EE

Family intervention
[]:ID No family intervention

Fig. 1. Relapse rates from three


studies contrasting family interven-
tion program with the absence of
such a program (all schizophrenic
patients on continuous medica-
etal.,
tion).
Six month loliow-up Nine month follow -up Nine month lollow-up
Impact of Family Intervention Program 187
status from high to low, and where this shift system. Of the 39 families who participated
did not occur relapse was more likely. initially, 3 dropped out, and of these 34
However, as Strachan, Goldstein, and completed both assessments. The total
Miklowitz (Chap. 4) indicated previously, number used in our analyses was reduced to
this merely documents a change in attitudes 33 because a father in one family failed to
expressed to an interviewer during a repeat show up for the posttest assessment. The
Camberwell Family Interview, but does not data will be described below. Further de-
indicate that family behaviors have chang- tails of the analyses have been reported
ed. In Los Angeles, we have attempted this elsewhere (Doane, Falloon, Goldstein, and
type of evaluation with data from the Fal- Mintz, 1985; Doane, Goldstein, Miklowitz,
loon et al. study summarized in this volume. and Falloon, in press).
The reader is referred to Chap. 14 (Falloon) First, we examined whether there was a
for a full description of that study. To sum- greater decline in the negative affective
marize , it involved a comparison ofindivid- style codes of criticism and intrusion for
ual and family therapy for schizophrenic pa- parents in family therapy than parents of
tients maintained on phenothiazine med- individually treated patients. To test this,
ication. the total number of these types of parental
Before each family entered their respec- statements were summed over the two
tive psychosocial treatment program, they problem discussions, and analysis of co-
participated in a pretherapy family assess- variance was carried out in which the pre-
ment task. This was the direct interaction therapy scores served as the covariate for
task described by Strachan et al. (Chap. 4), the posttherapy scores. These results are
in which two problems were discussed with presented in Figure 2 where we see that the
an experimenter present. After the first 3 incidence of negative affective style mes-
months of treatment, this procedure was re- sages was markedly lower in the family-
peated. The problems discussed were de- treated group [F = 9.41 (1,30) P < 0.005].
veloped in a similar fashion as for the pre- A breakdown of the data for criticisms and
therapy assessment. The problems used intrusions revealed highly significant reduc-
were those identified as idiosyncratically tions for both types of negative affective
relevant to each family at the time each as- communications for relatives in the family
sessment took place . as contrasted with the individual treatment
The interactions were audio-recorded, groups [F for criticisms = 5.49 (1,30) P <
and verbatim transcripts of these discus- 0.05; Ffor intrusions = 8.1 (1,30) P < 0.01].
sions were coded blindly by raters using the This sample consisted of an equal num-
Doane Affective Style (AS) (Doane, Fal- ber of single- and dual-parent families. We
loon, Goldstein, and Mintz, 1985) coding then tested whether the contrast between
20

18

16
14
o
OIl

~ 14
.,
s::
.0 10
~
"8 16
u
~ 6
4
Fig. 2. Total number of critical and intrusive
statements at 3 months post-test, by therapy 2
group (adjusted means).
Family Individual
F = 8.052 . dl 1/29. therapy therapy
P< 0.008
For treatment group
188 M. J . Goldstein and A. M. Strachan
24

20
18
rn ~ Pre-therapy assessment
0
.;::; 16 _ 3 Month post-the rapy assessment
«l
.r::
<Il
.D 14
"0
<Il
"0
0
12
(.)
(f)
« 10
'0
Q; 8
.D
E
;:)
c:
6
(ij
(5 4
I-

single parent dual pare nt single parent dual parent


families families famil ies families
Individual therapy Family therapy
Fig. 3. Pre-post changes in AS by family composition and therapy group.

the parents in the family or individual treat- tween the reduction of negative affective
ment groups was valid for both types of fam- communication in a parent, or parents, and
ilies. Figure 3 gives pre- and post-AS data the likelihood of relapse in the patient off-
for both types of family structures by treat- spring. To deal with these two questions,
ment condition. We see that there is a com- the 33 families were divided into three
parable reduction in the sum of criticisms groups based on the patterns of pre- and
and intrusions for both types of family post-AS scores. Since the British work on
structures in the family treatment condi- EE treats criticism and overinvolvement as
tion. Interestingly, while there was little or independent dimensions in defining EE sta-
no change in the level of negative AS state- tus, we considered the rate of change in crit-
ments for single parents in the individual icism separate from the rate of change in in-
treatment condition, there are suggestions trusiveness. Families were thus classified
of a worsening affective climate in the dual- into three categories: (1) dual increase, in
parent families when only the patient is which both criticism and intrusiveness in-
treated. This was quite intriguing, but un- creased from pre- to posttest, (2) dual de-
expected, as we had anticipated that the crease, in which both declined during the
single parents, because of their limited same period, and (3) a mixed group in
marital support system, might deteriorate which one attribute increased while the
more without family treatment. other decreased. Figure 4 presents the fre-
The pattern of group means suggests the quency of each type of family change pat-
Falloon family management approach does tern by treatment group, and it also pre-
indeed reduce the average level of negative sents the number of relapse cases that oc-
affective communication in parents of curred in each of these pattern-based cate-
schizophrenics. However, an average does gory groups. First, we see that the dual in-
not tell us how many families reduced this crease pattern is found in half of the individ-
behavior in each treatment condition nor ual therapy families but only rarely appears
does it establish a precise association be- in the family therapy group. Conversely,
Impact of Family Intervention Program 189
Family therapy Individual therapy
(n = 17) (n = 16)
10

(/)
Q)
6 o No relapse
(/) • Relapse
C1:l
0 4

0
01 MX 00 01 MX 00

Change in criticism/intrusiveness
Fig. 4. Patterns of change in AS in individual and family therapy. DI = dual increase; MX = mixed;
DD = dual decrease.

the dual decrease pattern is prominent in cently been reported by Doane et a1. (1985)
the family-treated cases, but less frequent which involved the ratings of coping effec-
in the individual therapy condition. The fre- tiveness alluded to earlier. Doane et a1.
quency of the mixed pattern does not vary classified families at the 3-month assess-
by treatment groups. Thus, there is a clear ment as relatively benign or negative in AS,
trend for reduction in one or both forms of on the basis of parental behavior in the in-
the negative AS behaviors in the family tre- teraction task. Her classification was based
atment condition. on whether the parent(s) reduced the num-
All but one of the relapses occurred in the ber of harshly critical remarks (personal cri-
individual therapy condition, and all but ticisms, guilt-inducing remarks, or critical
one occurred in the dual increase or mixed intrusions) or reduced the number of in-
groups. The probability of relapse for indi- trusions below a previously determined cut-
vidually treated patients in or of these two ting score of six. Within the family therapy
groups is 67% compared with 25% for the condition, negative AS status was associat-
dual decrease group. These data show that ed with lower coping than the benign AS
88% of families in family therapy have a re- families at the 3-month point. However,
duction in one or both dimensions of AS in after 3 more months of family therapy, the
contrast to 50% of those in the individual differences between the two AS groups had
therapy condition. Increases in AS are as- disappeared and both, in fact, showed sig-
sociated with relapse in that condition as nificantly higher levels of coping than either
well. What is puzzling is that there are some AS group in the individual therapy condi-
cases in the family therapy condition who tion, who had in fact deteriorated in coping.
show the dual increase pattern (n = 2) or Thus, while there are some families who
the mixed pattern (n = 6) who did not re- had not reduced their negative AS by 3
lapse. Of course, this reassessment of the months, they did show improvement with
families occurred after only 3 months of sustained family therapy, and this improve-
family therapy, and it is possible that with ment in coping is associated with a signifi-
sustained therapeutic contacts over the sub- cantly lower rate of patient relapse than was
sequent 6 months, changes in the affective found in the individual therapy condition.
climate of these families did occur which In the latter condition, there seemed to be
prevented relapse. little change in family coping effectiveness
Data supporting this hypothesis have re- following the 3-months assessment.
190 M. J. Goldstein and A. M. Strachan
Discussion
The various studies summarized in this form of problem solving takes the place of
chapter indicate that the affective climate of the negative interaction patterns of criti-
the family with a schizophrenic young adult cism, blaming, and intrusiveness into the
offspring relates to the short-term course of inner state of the patient. When a large re-
the disorder. Further, when family-based duction in the negative AS behaviors (in the
interventions are associated with a longer form of redcutions in both criticism and
period of community tenure for the patient, intrusiveness) has occurred, a major shift in
parallel reductions in this negative affective this more affectively neutral, task-centered
climate are noted in direct observations of behavior is observed; the reverse is noted
family behavior. The optimum results were when heightened levels of both forms of AS
found when both components of the AS are evident. These data suggest a marked
system, criticism and intrusiveness, were reciprocity between uncontrolled negative
reduced in frequency from pre- to a 3- affective expression focused upon the pa-
month posttest assessment, although be- tient and more controlled, cognitive form of
nefits were observed when only one com- behavior focused upon common family
ponent was attenuated. problems. Since we have only two points in
Whenever one type of family behavior is the Falloon study where direct interaction
reduced in frequency, it naturally raises the data were obtained, we cannot speak to the
question of what characterizes the new pat- sequential linkage between these two di-
tern of family transactions. A key objective mensions of family behavior. Does family-
of the Falloon et al. study was to train family based intervention first inhibit negative af-
members in a defined set of strategies for fective expression, thereby permitting the
dealing with problems inside and outside of acquisition of problem-solving skills? Or,
the family. A coding system was developed does the early acquisition of problem-solving
by Doane et al. (1985) for recording in- skills simply replace negative affective ex-
stances in the direct family interaction tasks pression without any specific instructions to
where family members utilized these re- limit or inhibit these behaviors? Further
commended problem-solving strategies studies with repeated observation of the
(PSS). When pre- and 3-month direct in- family therapy process are needed to tease
teraction tasks data were contrasted in the apart these issues - issues that are critical to
number of PSS behaviors expressed, there understand if were are to plan more effective
was a highly significant difference between programs for optimizing family change.
treatment conditions at 3 months favoring An interesting finding was that family
the family-treated group (adjusted mean coping responses to external life events im-
FT = 24.59; adjusted mean IT = 10.39, F = proved over time in the family therapy con-
6.60, P < 0.02). Also, when the pattern of dition, particularly in the families with
change in AS presented in Figure 4 was negative AS profiles. Unfortunately, the
examined for PSS change levels, sharp dif- measure of coping was very global, and thus
ferences were found between the dual de- it is not known whether the improvement in
crease groups in family therapy and dual in- coping represents changes in behavioral,
crease group in individual therapy in the 3- cognitive, or emotional responses. Hatfield
month data (mean PSS for dual decrease FT (1981) studied coping in the families of the
= +20.0; mean dual increase IT = -0.20). mentally ill and found that coping varied
This means that in the former group there on a number of dimensions: emotional
were 20 more instances of PSS behavior mastery, cognitive skill in understanding
than was evident at pretest, while in the lat- the illness and learning management strate-
ter there was virtually no change from base gies, and the extent to which relatives main-
line. The remaining AS change groups sho- tained outlets for their own personal needs.
wed slight positive changes in scores that An important avenue of research would be
were similar in the two treatment condi- to understand the development of family
tions. member's abilities to cope over time and
These data suggest that a task-centered the interaction with their style of emotional
Impact of Family Intervention Program 191
expression. interventions typically cease or patients are
Much of this chapter has emphasized the transferred to some other clinical unit or
impact of a combined program of phar- service. What happens to those patients and
maco- and family therapy on relapse rate their families at this point? Do they start to
over a 9-month to I-year period after dis- relapse rather rapidly or do they continue to
charge for an episode of schizophrenia. It is hold the gains observed during the "offi-
obviously an important criterion for a suc- cial" treatment period? Evidence concern-
cessful maintenance program, but relapse ing maintenance or deterioration in both
prevention is a minimal criterion for a treat- the patient and intrafamilial relationships in
ment program. Can a family intervention general would be useful. If there is little re-
program extend beyond this minimal ob- tention of the gains observed during the
jective to facilitate improved social role controlled trials, it does not imply that these
functioning? The data here are far from drug and family programs are without
complete. Findings from the Falloon et al. value. Instead, they could suggest that the
study do suggest that significantly greater treatment of schizophrenia requires a type
improvements in social role functioning of longer-term commitment than most re-
were observed in the family than in the indi- search studies can typically guarantee.
vidually treated group. Also, the recent re- One final issue, because the emphasis of
port by Doane et al. (1985) indicates that a this chapter has been upon the family of the
reduction in negative AS from pre- to 3- schizophrenic and family-oriented treat-
month assessment was associated with high- ment programs, we have not emphasized
er levels of social functioning than when this issues concerning the long-term pharmaco-
was not the case. Also, Anderson et al. therapy of the patient. We should never for-
(this volume) report improvements in social get that all of the successful family pro-
role functioning when families were in the grams are built upon a foundation of regular
family therapy condition. Thus, it appears and continuous pharmacotherapy. How-
that modifications of the affective climate ever, the successful addition of family-
of the family achieves more than relapse based intervention programs to regular
prevention and is associated with greater pharmacotherapy raises the question of
social improvement as well. Despite these whether a potent social therapy permits
encouraging findings, it is still not clear alteration in the strategy of drug treatment
what level of social improvement is possible in terms of dose level and pattern of treat-
when such a multimodal program is con- ment. Given the evidence that a com-
tinued beyond the 9-month point of active prehensive family intervention program
treatment used in the Leff et al. and Falloon produces some degree of stabilization of the
et al. programs. Certainly, the optimistic stress level in the social environment, we
results to date warrant continued efforts to can now consider whether this stabilization
test the limits of efficacy of such programs. permits the use of lower dose levels of phe-
Along these lines, it would be very help- nothiazine medication or even more radical
ful to gather data concerning the long-term strategies, such as intermittent or targeted
impact of these family-focused programs use of medication. An ironic side effect of
after they officially cease. Most of the con- an effective family program may be that it
trolled trials described in this paper have permits greater latitude for experi-
offered drug and family interventions for mentation in the complementary area of
roughly half of their sample for a fixed time psychopharmacology.
period. At the end of the time period, these

References
Doane, 1. A., Falloon, 1. R. H., Goldstein, M. Doane, 1. A., Goldstein, M. 1., Miklowitz, D. 1.,
1., and Mintz, 1. (1985). Parental affective style and Falloon, 1. R. H. (in press). The impact of
and the treatment of schizophrenia: Predicting individual and family treatment on the affective
course of illness and social functioning. Ar- climate of families of schizophrenics. British
chives of General Psychiatry, 42, 34-42. 10urnal of Psychiatry.
192 M. J. Goldstein and A. M. Strachan
Goldstein, M. J., Rodnick, E. H., Evans, J. R., study. Journal of Psychiatric Treatment and
May, P. R. A., and Steinberg, M. R. (1978). Evaluation, 3. 11-19.
Drug and family therapy in the aftercare of Vaughn, C. E., and Leff, J. P. (1976). The influ-
acute schizophrenic. Archives of General ence of family and social factors on the course
Psychiatry, 35,1169-1177. of psychiatric illness: A comparison of schizo-
Hatfield, A. B. (1981). Coping effectiveness in phrenic and depressed neurotic patients. Brit-
families of the mentally ill: An exploratory ish Journal of Psychiatry, 129, 125 -137.
16. The Psychosocial Program of Treatment
of Schizophrenic Patients in the
Crakow Psychiatric Clinic
B. Barbaro, A. Cechnicki, A. Szymusik, K. Zawadzka, and J. Zadecki

Community Psychiatry in Poland


Polish psychiatry is still under the influence university centers. They have not eliminat-
of the nineteenth century model, which em- ed the key position of hospitals in the health
phasized large psychiatric hospitals. The care system. The lack of modern legal re-
image of these hospitals corresponds to that gulations, lack of social organizations ready
of the large state hospitals as previously de- to aid the movement seeking to provide
scribed by Goffman (1961). help for those suffering from psychiatric
The ideology of "hospital centralization" diseases, financial difficulties, difficulties in
is a direct descendent of the medical model the coordination of the existing social serv-
of the organization of health care. Recent ices, and the lack of suitably trained "social
changes within the hospitals, as well as the workers," etc. have all hindered the de-
development of community-based forms of velopment of community psychiatry in
treatment, have occurred in only a few Poland.

General Data on the Crakow Clinic


The psychiatric clinic is situated in the cen- The wards of the clinic (for young people,
ter of Crakow among other university clin- children, geriatric, neurotic, and two psych-
ics. At present the inpatient department otic patients) take patients regardless of
houses about 120 patients, while in the en- their place of residence, although most of
larged outpatient department about 1000 them come from the town of Crakow.
patients are treated.

A Glance at the Sociology of the Institution


In 1951, the psychiatric clinic gained auton- ter "to the individuality and personality of
omy and a separate site. Previously, it had the patient and physician". It corresponded
been part of the psychiatric-neurological to a more "familiar" style of relationship
clinic. In the last 3 decades, the clinic de- among the medical personnel (in spite of
veloped from a closed, uniform organiza- the hierarchical structure of the hospital)
tion system toward an open and differen- and a great limitation of the patients' free-
tiated one (Szymusik, Cechnicki and, dom. The theoretical foundations of treat-
Zadecki, 1982). This development, which ment were influenced by E. Kretschmer's
paralleled the sociopolitical transformation and E. Bleuler's classical German psychia-
in Poland as well as that in psychiatry world- try. Pavlos's influence was felt and to some
wide, went through three phases. slight extent, that of classical psychoanaly-
Phase 1: "Asylum" (1951-1955). The SIS.
clinic operated during this phase to segre- Phase 2: "Renovation of the Hospital and
gate patients from society and to give shel- the Organization of the Clinical Based on
194 B. Barbaro et al.
Therapeutic Groups" (1955-1975). During groups, which undertook their work in the
this phase, the change within the clinic fol- newly organized treatment settings (day
lowed the English emphasis on therapeutic wards, hostels, therapeutic camps, differ-
communities publicized in the mid-1950s. entiated ambulatory treatment of the pa-
This shift in theoretical model was a crucial tient and his family, etc.). Although the in-
change. Most of the changes were part of a stitutions founded on the therapeutic com-
dynamic process which is still in progress munity notion and group psychotherapy
today. During this period, the emphases of developed parallel in time to the English ex-
American dynamic psychiatry on the one periments in the 1950s, the newer forms of
hand and of the existential-phenomenologi- partial hospitalization and of therapeutic
cal movement on the other were assimilated lodgings appeared later. During phase 3,
into the hospital system. the psychiatric hospital became a part and
Phase 3: "Branching of the Outpatient no longer the center of a complex system of
System" (1975-1981). This phase corres- psychiatric care.
ponded to the "separation" of therapeutic

Group-Oriented Community Treatment of Schizophrenia


One of five therapeutic groups in the clinic the particularly human-value subsystem,
is devoted to the treatment of schizophrenic with similar attention.
patients. Paranoidal states, schizoaffective
psychoses, borderline states, and deep dis-
Organization Model
turbances of personality with noncharac-
teristic psychotic phenomena are also in- The psychotic ward of less than 20 beds
cluded within this group. Patients are usual- forms the basis of the hospital. The day
ly between 18 and 35 years old and live in hospital with the therapeutic family group
Crakow. There are 20 persons in the was opened 3 years ago when the other
groups: physicians, occupational thera- parts of the system were already completed.
pists, psychologists, nurses, a social wor- The day hospital is situated on one floor of
ker, and a sociologist. a multifamily housing complex in the center
oftown. The club offormer patients and the
section of the Polish Tourist Association
Pragmatic Plan
run by them are also situated there. The day
In our social model of therapy, we are con- center is also the meeting place for the
cerned with concentrating on the process of patients who have left after having been in
communication and on social training for ambulatory care for several years. A hostel
the relationship between the patient and rented by the clinic from private owners
those around him or her. Thus, we oppose forms another part of the system. The inpa-
the tendency noticed in those who suffer tient ward is prepared to receive, when ne-
from schizophrenia to increase the isolation cessary, an outpatient or an inmate of the
system. hostel. Therapy is also carried out in a shel-
Professional psychotherapy constitutes ter in the mountains where therapeutic
only a small segment of the treatment. An camps are organized every year, as well as
integrated approach is possible only in the patient's home.
through the linkage of various types of ther-
apy: linking inpatient with outpatient ther-
Inpatient Ward
apy and 24-h care with part-time care and
partial hospitalization. Therapy of acute psychotic states is carried
It is necessary to "introduce" those out in the inpatient ward, where an attempt
people closest to the patient, particularly is made to reduce the length of the patient's
the family, to the process of therapy and to stay to a minimum. The basic problem dur-
treat the various subsystems, e.g., the body ing inpatient treatment involves maintain-
subsystem, the information subsystem, or ing a balance between reality and the world
The Psychosocial Program of Treatment 195
of the patient's imagination and delusions. the following criteria: (a) the acute psycho-
One major goal is to rebuild a sense of social tic symptoms have disappeared, (b) the sui-
and individual identity. An emotional rela- cide risk has disappeared, (c) the optimum
tionship with the individual therapist is a therapeutic dosage of drugs has been
basic conditon in this process. Individual reached, (d) basic group abilities have been
care is undertaken not only by phsyicians achieved, (e) basic practical abilities have
but also by experienced nurses and psycho- been realized, e.g., going to town inde-
logists, with the physician serving as a con- pendently, and (f) a positive motivation to
sultant in the matter of drugs. continue psychiatric treatment has been
The purpose of all the therapeutic, phar- achieved.
macological, individual, and group meth- These criteria require a short commen-
ods is to rebuild emotional communication tary. The attenuation of acute psychotic
with the people around the patient before symtoms is relatively easy to evaluate, yet
the psychotic phenomena disappear. Non- persisting hallucinations or delusions do not
theless, there is a progressive shift from in- constitute a contraindication for moving the
dividual to group contacts. In addition to patient to the day ward. The level of anxiety
the daily, large group meetings of the thera- and secondary adaptation to the symtoms
peutic community, there are a wide variety determines what course of action is subse-
of group experiences which reflect the so- quently taken. The necessity of evaluating
ciocentric model of therapy (sports, group the risk of suicide needs no explanation.
psychotherapy three times a week, excur- Reaching the optimal dosage of drugs in-
sions, occupational therapy organized by volves evaluation of the individual's bio-
the leaders of the ward). The purposes of logical reaction to the neuroleptics. We
the therapy in the day ward are clear: we try have noticed that despite the appearance of
to introduce the patient into the "common additional symptoms connected with taking
area." Several almost ritualistic activities neuroleptics the dosage should not be ra-
are dealt with during the therapeutic com- pidly reduced for a patient who after trans-
munity meetings, such as the election oflea- fer to the day ward encounters a more com-
ders, the establishing of the hours of duty at plicated social situation. Perhaps it is ana-
the door of the ward, reports on the week- logous to a family with a high index of ex-
end spent outside the hospital, planning of a pressed emotion (Brown, Birley, and
common afternoon, introduction of new Wing, 1972; Kuipers, 1979; Vaughn and
patients and saying goodbye to those leav- Leff, 1976). The achievement of basic group
ing, which tend to reinforce a constant abilities is connected with a readiness to
structure of common situations. This type receive feedback from the group. Finally,
of communication bears fruit in increased the practical abilities are limited to going to
activity and enhanced initiative among the town on one's own and basic self-care.
patients. This emphasis on self-efficacy is The motivation for psychiatric treatment
critical from the first moment the patient is is usually feigned when presentation is the
received into the inpatient setting. There is result of pressure from the patient's family
frequently an inherent conflict between or other contact persons and the patient is
these socially oriented therapy programs sometimes hospitalized involuntarily.
and the expectations of the schizophrenic Ambulatory treatment is the result of at-
patients, probably related to the main sym- tachment to the institution or the therapist
ptoms of the disease, such as suspicious- who established emotional contact with the
ness, social withdrawal, and anhedonia. patient. When transferring the patient to
This should be understood as one aspect of the day ward, we expect at least a trace of
the complex process of establishing com- authentic motiviation. This motivation is
munication between patient and staff on the not always associated with full insight into
unit. the disease. Often the patients lose interest
The stay of the patient in the ward aver- in the psychotic contents of their dreams,
ages about 3 weeks. From among 140 pa- but on the other hand, in the group they fre-
tients treated during the year, half transfer quently become aware of severe personality
subsequently to the day ward, if they fulfill problems.
196 B. Barbaro et al.
Day Hospital the plan of the day. The style of work in the
group is similar to the interactive groups
As mentioned previously, greater impor- described by Kayser et al. (1973), where
tance is attached to the patient's own mo- stress is placed on the present situation of
tivation to participate in therapeutic activi- the patient and a minimum of attention is
ties. Patients transferred from the inpatient devoted to the conflict from the past. In a
ward of the clinic constitute 75% of the day group of this kind it is easier to correct pres-
hospital population, and the remaining ent behavior with the support of the group.
25% come from various psychiatric wards Psychodrama is central for demonstrating
or outpatient care. The average length of actual conflicts before the group. Group
stay is about 7 weeks. The day hospital ther- psychotherapy forms an institutional
apy area is shared together with the family framework for communicating, and
group, the club of former patients, and the through socialization it lessens the feeling
outpatient clinic. Thus, the day hospital of isolation and loneliness of patients suf-
performs its part of the rehabilitation pro- fering from schizophrenia.
cess (Howells, 1968) and is directed mainly Another type of group is oriented to crea-
at patients who, having gone through psy- tive activity, in which spontaneity and try-
chosis, are left with feelings of emptiness, ing ou of new parts are encouraged. It takes
insufficiency, ruptured or feeble bonds with place during paratheater, choreotherapy
their previous peers, a readiness for with- and art sessions. Self-help is required and
drawal, which has been increased by the the patients themselves prepare breakfasts
disease and a stay in the hospital, and a state and lunches from supplies provided, per-
of postpsychotic depression while searching mitting the practice of skills, the lack of
for their place in society. The whole sur- which is often described as the "life aprag-
rounding reality of the ward has as its aim to matism" of those suffering from schizo-
create a "corrective family atmosphere," phrenia. Finally, many therapeutic activ-
which allows the patient's social abilities to ities are oriented toward creating a thera-
develop. The family-oriented therapy pro- peutic milieu with an emphasis upon mutual
gram is possible only with close cooperation coexistence and cooperation such that a so-
between the families and the ward staff. cial field is created for individual decisions
Through the direct association with the and personal responsibility. This is found
primary group, the family, and the thera- everywhere within the therapeutic com-
peutic group on the ward, it is possible to munity: the day hospital, the classes held
work through the current conflicts and for the former patients club, the section of
mutual involvements in the primary group. the Polish Tourist Association, and at the
One of the sessions is called "My family therapeutic camp (which is the climax of
today and tomorrow" and is conducted by each year's work at the day hospital and
the family therapists, who hold similar ses- where most of the patients who had been
sions for the patient's families. treated during the year meet).
The day hospital offers a 40-h program of Those parts of the system not described
therapy 5 days a week and once a month a here in more detail emphasize the patients'
weekend excursion into the mountains with own numerous activities, while the part
the Polish Tourist Association. The patients played by the psychiatric institution is mini-
are gradually prepared to take up work or malized.
study. The group cooperates closely with
the Trade Advisory Center, trying to
Family Therapy Unit
achieve a return to work in full-time jobs for
this group of young patients 18-35 years As mentioned above, this unit occupies the
old. Only a small percentage of patients re- same area as the day hospital and exerts a
turn to institutions offering protected work decisive influence through its close co-
(sheltered workshops). operation with the day hospital. Our under-
The day program of the ward is filled with standing of schizophrenia is expressed in a
various group activities. The daily 90-min lecture: "Values, aims, and aspirations and
psychotherapy group has a central place in the crisis of identity experienced by those
The Psychosocial Program of Treatment 197
suffering from schizophrenia," in which we rence and requires "home care." With
describe more fully the initiation and de- every contact, the family's ability to carry a
velopment of disturbances within the family further burden and the harmfulness of the
system and in the complex pathological patient's increasing isolation in his own
communication within the family. We em- home are evaluated.
phasize that the individual and social reac-
tions to the illness do not exist separately
from each other. An understanding of the Live-in Community Hostel
implications of the illness must take into ac- The hostel is a transitional form with a de-
count both the person and the milieu in finite social program. The therapy in the
which he/she lives. hostel is directed at the development of the
person through real life experiences. The
Clinical Experience
institution's role consists in introducing into
the group a "hostel adviser" from the thera-
During the first 2 weeks of the patient's stay peutic group, who lives in and shares every-
in the inpatient hospital, the therapist initi- day life with the patients. The general aims
ates a home visit without the patient's pres- are to develop, in a small group, important
ence. This is done after all the family mem- emotional bonds and to enhance the abili-
bers have agreed. On the part of the thera- ties needed to deal with life so that a more
pists these visits are participant observa- independent life is feasible. With a periodic
tions. The aim of the visit is to produce a separation from the family there is a good
dynamic diagnosis of the family which de- chance of regulating the disturbed relations
fines, at least, the complexity of communi- which have existed in the family group,
cation among the members of the family e.g., an excessive overinvolvement with the
group. One therapist from the family treat- patient. Patients are assigned to a hostel
ment group and one from the day hospital straight from the day hospital or while in
or the inpatient hospital take part in each ambulatory care. Two therapists from the
such visit. The goal is to experience the real hospital visit the hostel once a week at the
atmosphere in the family as perceived hostel community meeting and analyze the
through the medium of the therapists' emo- course of the previous week. The close co-
tions, which are later analyzed. The scheme operation of the hostel adviser, the visiting
of the diagnosis follows, that published by therapists, oriented to the development of
Howells (1968) and is subsequently trans- the group as a whole, the individual thera-
mitted to the therapists conducting the fam- pist, who is most often one of the members
ily therapy. In addition to the family thera- of the day hospital, and the family therapy
py described above, work with a multifami- group makes it possible to implement a
ly group with patients has recently been coherent treatment strategy based on
undertaken. Both the patients and their mutual agreement. It often happens that
families have earlier experiences from the families of the inhabitant remain in the
groups in which they have participated that multifamily group with the patients while
have a decisive influence on the group the patients reside in the hostel. It allows
dynamics. still another opportunity for the whole
We have noticed advantages of such a family to assimilate new experiences.
form of therapy in addition to the greater
economy compared with each family having
its own therapist. Thus, meetings with indi- Hostel Adviser
vidual family units most often have a diag- The hostel adviser of the therapeutic com-
nostic character, giving one more glance at munity hostel, who lives with the psychotic
the family as a whole from another per- patients for about a year, has a difficult
spective, or allow intervention when the pa- task. Since the hostel came into being in
tient is already in ambulatory care and the 1976, eight persons have undertaken this
family is in a crisis. Similarly, therapists oc- role. They need to overlook professional
casionally come into contact with the family limitations and to avoid any conflict of
of a former patient who has had a recur- loyalty between the group of patients and
198 B. Barbaro et al.
the therapeutic group. The feeling of be- Principle of Continuity in the Process of
longing to the group of inhabitants must be Therapy
emphasized. The expression of aggressive-
ness is usually a critical event and is usually The continuity of the treatment depends on
followed by good communication between an administrative structure which encour-
the adviser and the members of the group. ages entry into transitional forms of treat-
The adviser functions in the hostel as a ment after the patient leaves the hospital,
model to be imitated. His close proximity e.g., day hospital, hostel, and, depending
exposes him to intensive feelings, transfer- on the individuals' needs and abilities, into
red and countertransferred. The hostel ad- varied ambulatory care programs such as
viser requires intensive help and an analysis the club of former patients, individual ther-
of his own emotions with the help of the the- apy, family therapy, therapeutic camp, and
rapists visiting the hostel. the Polish Tourist Association section.
Such prolonged living together with schiz- Continuity of care requires at the very least
ophrenic patients is an invaluable method a number of years of the various therapies.
of developing the abilities needed to coexit This continuity is guaranteed by partici-
with patients in close proximity. The specif- pation in the same therapeutic group over
ic range of problems and difficulties associ- the years. The group fulfills, for the pa-
ated with such an experience would require tients, various therapeutic functions by pro-
a separate chapter. As in a lens, the practi- viding a chance for manifold relationships
cal problems of therapy are brought into to develop.
focus. When seen at such close quarters the
psychopathological symptoms do not look
Principles of Work in the Group
like symptoms, and they need nontradition-
al solutions. The complex tasks are orchestrated by the
interplay between the main therapists and
the auxiliary therapists. Although each pa-
Principle of the Small Group
tient always has his own individual thera-
The system of therapy described above is pist, it is important that he/she can tum to
based on small groups of 10-12 persons. different members of the group for assist-
The hostel has only seven residents. The ance depending on his therapeutic situa-
developemnt of these groups enriches the tion.
therapy by providing realistic life experi- The functioning of the groups is based on
ences. It is done mostly outside the psychia- the principle of rotation. Once a year a
tric hospital, on the basis of emotional meeting of the group is held, which lasts a
bonds that can be sustained when the dis- few days, in which a summary of the work
tance between the members of the group is accomplished to date and plans for the com-
small. ing years are presented. The rotation of
people into particular subgroups takes into
account both the patients' and the thera-
Problem of Distance
pists' needs, the need for reciprocal school-
The autism described in schizophrenia re- ing, and deadlines established for thera-
quires putting the patient in contact with his peutic or research tasks in the groups.
milieu (therapist) but also the milieu (thera- With this multiplicity of therapeutic
pist) must be put in touch with the patient. tasks, constant ongoing supervision is nec-
The various systems of therapy can be eval- essary. This is carried out in small thera-
uated from the point of view of this peutic groups; for example, one of the ther-
distance. The distance is almost automatic- apists from the family therapy section is a
ally connected with differently organized supervisor of the inpatient hospital. The so-
structures. Thus, the psychopathological called Balint groups (Balint and Balint,
symptom is a dynamic function of the entire 1962) undertake other problems of patients
complex social structure in which it is mani- and their therapists. In Crakow there are
fested and observed, depending on the five such groups and the majority of the
point of observation. therapists participate in them.
The Psychosocial Program of Treatment 199
The Most Difficult Task pseudoindependence which is manifested
The most difficult task consists of treating by breaking all of the bonds established
the schizophrenic patient without creating a during therapy. The work of motivating the
deep dependance on the therapist or the patient for the therapy should be based on
therapeutic system. It happens sometimes the expectation that a phase of dependence
that the patient passes from a deep depend- will be followed by a phase of cooperation
ence on the therapist and family to a type of based on mutually established conditions.

Final Remarks
Psychosocial models have begun to play an ble onte to predict which patient will profit
increasingly important part in the treatment from a rehabilitation program (Klar, Fran-
of schizophrenia (Stierlin, Wynne, and Wir- ces, and Clarkin, 1982). It is a positive de-
sching, 1983). The model described here pro- velopment that various systems of therapy
vides more intensive treatment and re- take into account the patient's individual
habilitation than is possible in traditional needs. This permits therapists to compare
ambulatory treatment. Through its many their experiences and the results of research
links, such as the day hospital or the hostel, (Anthony, Cohen, and Ray, 1978; Katsch-
high expectations for change are rein- nig, 1985). The fairly homogeneous popula-
forced. tion of our patients in terms of age, the pre-
The greatest dilemma confronting the cli- cisely determined diagnostic criteria, and
nician preparing such a social treatment the specific description of various forms of
program is whether the patient can profit therapy used in our system permit further
from a less intensive ambulatory treatment, longitudinal research to evaluate both the
such as traditional individual psychothera- total model and the suitability of the various
py and supportive neuroleptic treatment. components for any given patient.
There are not patient attributes which ena-

References
Anthony, W. A., Cohen, M. R., and Ray, V. dology in evaluation of psychiatric treatment.
(1978). The measurement of rehabilitation out- Cambridge: Cambridge University Press.
come. Schizophrenia Bulletin, 4, (3). Kayser, and Mavers, W. (1973). Gruppenarbeit
Balint, M., and Balint, E. (1962). Psychothera- in der Psychiatrie [Group work in psychiatry].
peutische Techniken in der Medizin. Stuttgart: Stuttgart: Thieme.
Klett. Klar, H., Frances, A., and Clarkin, 1. (1982).
Brown, G. W., Birley, J. L. T., and Wing, 1. K. Selection criteria for partial hospitalization.
(1972). The influence of family life on schizo- Hospital and Community Psychiatry, 33,11.
phrenic disorders: A replication. British Jour- Kuipers, L. (1979). Expressed emotion. A
nal of Psychiatry, 121,241-258. review. British Journal of Social and Clinical
Cechnicki, A., Zawadzka, K., Rostworowska, Psychology, 18,237-243.
M., Zadecki, J., and Barbaro, B. (1984). Die Stierlin, H., Wynne, L. C, and Wirching, M.
sozialpsychiatrische Tagesklinik fUr schizo- (Eds.) (1983). Psychosocial intervention in
phreniereagierende Patienten [The Socio- Schizophrenia. An international view. Heidel-
psychiatric day clinic for patients with schizo- berg: Springer.
phrenic reactions]. Paper presented at the Szymusik, A., Cechnicki, A., and Zadecki, J.
XVth Symposium of the DAP, Munich. (1982). Die Entwicklung der Idee der dynami-
Goffman, E. (1961). Asylums. Essays on the schen Psychiatrie in der Psychiatrischen Klinik
social situation of mental patients and other der Medizinischen Akademie in Krakow
inmates. Chicago: Aldine. [Development of the idea of Dynamic Psychia-
Howells, J. G. (1968). Theory and practice of try in the Psychiatry Department of the Aca-
family. Edinburgh: Oliver and Boyd. demy of Medicine in Crakow]. Paper presented
Katschnig, H. (1985). Methods of measuring so- at the XIVth Symposium of the DAP, Munich.
cial adjustment. In T. Helgason (Ed.), Metho-
200 B. Barbaro et al.
Vaughn, C. E., and Leff, J. P. (1976). The influ- phrenic and depressed neurotic patients. Brit-
ence of family and social factors on the course ish Journal of Psychiatry, 129, 125-137.
of psychiatric illness. A comparison of schizo-
Epilogue

17. Coping and Competence as Protective Factors


in the Vulnerability-Stress Model of Schizophrenia
R. P. Liberman

Introduction
Schizophrenia is not to be understood as nerable person from stress-related, bio-
psychopathology alone, or as a set of bio- medical determinants of schizophrenic re-
logical impairments or deficits; rather, the lapse. One major source of protection
nature of schizophrenia is to be found in the emerges from studies of the familyenviron-
interfaces among environmental, behav- ment where supportive, tolerant, and
ioral, and biological factors. Some of these understanding relatives who exhibit realis-
factors endure over time and change only tic expectations for social performance
slowly in response to changes in the en- from a schizophrenic member can reduce
vironment. Biobehavorial factors operate relapse to 15% in 9 months following dis-
on the person as vulnerability to episodes of charge from the hospital (Vaughn et aI.,
schizophrenic symptoms when they endure 1982). On the other hand, ambient levels of
through periods of remission as well as re- stress and tension within the family can
lapse. Abnormalities in information pro- negatively affect patients who suffer from
cessing and attention as well as autonomic schizophrenia. When individuals with the
reactivity have been implicated as enduring specific psychobiological vulnerability to
vulnerability factors across illness episodes schizophrenia experience stress and tension
as well as in children at risk for schizophre- from family transactions, relapse or exac-
nia (Nuechterlein and Dawson, 1984). In- erbation of symptoms is made more likely,
adequate learning opportunities during with relapse rates exceeding 50% in the 9
one's developmental years can also lead to months after hospitalization. Family pat-
subsequent, enduring deficits in social and terns of stress are interactional as schizo-
occupational capabilities that may increase phrenic persons also produce stress on their
a person's susceptibility to schizophrenic relatives by virtue of their symptoms and
symptoms. For example, certain schizo- social impairments. This interactional pat-
typal traits have been posited as vulnerabil- tern leads to emotional overinvolvement
ity factors in schizophrenia (Chapman, and excessive criticism from relatives in
Edell, and Chapman, 1980). Furthermore, about two-thirds of Anlgo-American fami-
studies have demonstrated that premorbid lies (Vaughn et aI., 1984). Thus, family
social and occupational deficiencies can interaction processes, both unfavorable
predict subsequent symptomatic status and and supportive, go in both directions and
rehospitalization of schizophrenic patients can affect patients and their relatives in re-
(Strauss and Carpenter, 1981). Enduring verberating cycles.
biobehavioral vulnerabilities interact with Brief cross-sectional views of course and
transient, time-limited stressful life events, outcome seen at anyone point in time in our
longer-term environmental potentiators of assessments and follow-ups of patients with
risk to symptoms, and protective factors schizophrenia can be interpreted from
that operate at the environmental and per- a vulnerability-stress-coping-competence
sonallevels. model. These are really not "outcomes" but
Progress has been made in recent years in rather momentary "snapshots" of how the
identifying factors that can protect a vul- family environment, the social network,
8 ~ Personal vulnerability factors
3~ f3
('1) I-' r-------------~i i
o .
;:;J> Reduced Autonomic
Schizotypal
g..g Dopaminergic available hyperreactivity
personality :;tl
N-= dysfunctions processing to aversive
o :::t_ traits .."
'1:1 '" capacity stimuli
0" O.
.... (")
('1) (")
~
('1)
~-g
f6 Intermediate states Outcomes 3
-g ::l
'"
Personal protectors
=
e.. ~--------~i ~i----------~
Processing Social
q> capacity functioning
Coping overload
Antipsychotic
and
medication
I self-efficacy

Q
* Tonic Schizophrenic
= Prodromal
autonomic psychotic
symptoms
~ Environmental Protectors hyperarousal symptoms
fa
8.5- Family Supportive
OQ problem psychosocial
g. solving interventions Deficient
('1) Occupational
< processing
functioning
:::t_
'" of social stimuli
2:
('1)

'"
[ T Enviro~menital potentiators and ~tressl"'io_r_s__________--,
a
('1)
0- Critical or Over-
....
o emotionally stimulating Stressful
overinvolved social life events
§ family climate environment
;jl
('1)

8.o Feedback loop


Premorbid or remission period Prodromal period - - - - - - - - - -....-- Episode
!f.
Copying and Competence 203
and the individual's psychobiological vul- of schizophrenia. At present, we probably
nerability and personal coping are interact- know more about the influences at the envi-
ing to determine current levels of symptoms ronmental and behavioral levels affecting
and social functioning. Figure 1 depicts a schizophrenia than we know about the bio-
conceptual framework for organizing a vul- logical factors.
nerability-stress-coping-competence model

Case Example
To elucidate the vulnerability-stress-cop- which was supportive, nurturing, warm,
ing-competence model of schizophrenia, and friendly. The staff were helpful to him
we might think of a farm boy, Michael, who and seemed to understand his needs for pri-
at the age of 18 is recruited into military vacy and quiet. They did not expect much
service. He has spent all of this life in a rural from him. He did not have to polish his
and serene pastoral county, without very shoes or make his bed in the morning. He
much contact with people. He went to a received antipsychotic medication and
small school but avoided contact with other slowly but surely his symptoms subsided.
children. Most of his time was spent on the He began to tentatively socialize, and his
slopes of his native mountains, tending level of function returned to its premorbid
sheep and cows. He has poorly developed level.
social skills with peers. His parents were At this point, he was discharged from the
also socially withdrawn and did not provide military hospital and returned to his family
opportunities to learn expressiveness or home. Unfortunately, the protective fac-
intimacy. There was, at the genetic level, a tors provided by the military hospital did
grandfather who spent many years in the not get communicated to Michael's after-
state pychiatric hospital, presumably for a care system. The psychiatrist in the milita-
schizophrenic disorder. ry did not talk to the psychiatrist respons-
At the age of 18, Michael entered military ible for the rural clinic near Michael's home
training. He lived in a barracks full of other nor to Michael's parents. As a result,
young men, most of whom came from lar- Michael returned home to family members
ger cities. They talked openly, fast, and who were baffled and confused about what
loud. He was not used to this active and had happened to him. He looked normal.
stimulating social intercourse and he expe- There were no outward signs of illness. He
rienced difficulty in processing the incoming was taking some pills, which his parents felt
information. He did not know how to make made him sleepy and were a sign of weak-
jokes with his fellow recruits. He did not ness. His parents told him that he did not
know how to brag about his sexual exploits really need to have those pills as long as he
because he did not have any. After several ate his ample farm meals and drank a lot of
stressful weeks of trying vainly to cope with good milk. His parents urged him to again
the rigorous military discipline and peer work on the farm. Their expectations for his
pressure, he experienced confusion in his work capacity were as high as before, if not
thinking and autonomic symptoms of anxie- higher, because they were frustrated and
ty. These prodromal symptoms of psychosis annoyed with him for having failed to com-
were quickly followed by ideas of reference plete his military service.
and then delusions that thoughts were being As the performance demands on the farm
put into his head by his officers. He showed and pressures within the family mounted,
lapses in attending his regular duty, was Michael experienced the return of weird
awake at night, and was brought to the mili- feelings. He felt unreal and became obses-
tary hospital with florid hallucinations and sed with concerns about bodily decay and
delusions where the psychiatrist pronounc- dying. The long-acting antipsychotic med-
ed him as suffering from a schizophrenic ication was slowly metabolized and ex-
disorder. creted, and Michael again developed the
Michael then went into a hospital ward symptoms of schizophrenia.
204 R. P. Liberman
Reference to Figure 1 will enable the rea- tive capacities and social functioning; how-
der to chart the evolution and course of ever, returning home to family members in
Michael's disorder and to identify points of a tense and unsupportive home environ-
departure for therapeutic intervention. The ment led quickly to relapse when the pro-
prototypical patient, Michael, had both tective benefits of medication were with-
genetic and schizotypal personal vulnerabi- drawn.
lity to schizophrenia. As he was exposed to Several entry points for therapeutic inter-
the stressors of leaving home and entering vention present themselves, including fam-
the military, his personal and coping skills ily education and management, mainte-
and environmental support were inade- nance neuroleptic drug therapy, social skills
quate to protect him from the emergence of training, and less demanding vocational
psychotic symptoms. Prodromal symptoms and peer settings. The diagram in Figure 1 is
were associated with autonomic hyper- meant to highlight the reverberating cycles
arousal and cognitive overload and were and interactions among factors influential
precipitated by an overstimulating environ- in the course of schizophrenia. Protective,
ment in the military. potentiating, vulnerability, and stress fac-
The supportive framework of the military tors interact to determine the symptomatic
hospital combined with neuroleptic med- and functional status of a person at anyone
ication temporarily reconstituted his cogni- time.

Schizophrenia: A Multidimensional Disorder


Counteracting unidimensional thinking lapses.
about schizophrenia is difficult in contem- The research reported in this book also
porary psychiatry because of the strong raises the possibility that temporary re-
trends toward biological or psychopatho- lapses may be worth the price to pay to
logical determinism. Psychopathology is achieve greater gains in social functioning.
reified and viewed as having permanency In other words, patients and their families,
and pervasiveness well beyond its actual as well as responsible clinicians, might ac-
parameters. The ascendant neurosciences cept and tolerate a relapse if that relapse is
are uncovering more of the secrets of the in the service of the individual's confronting
brain, but we too quickly accept early data and eventually mastering the stress requir-
on PET scans, neurotransmitters and re- ed to compensate for premorbid deficits in
ceptors as the holy grail. We do not need to social functioning. It may be necessary to
engage in an ideological struggle over nur- encounter new life situations, risking exac-
ture vs nature in schizophrenia, but we do erbations and symptoms while learning
need to resist premature and simplistic bio- skills to improve social and occupational
logical theories of mental disorders. functioning. In fact, data supporting this
The chapters of this book begin the ardu- view were presented in Chap. 1 by Moller
ous journey of searching for the complex in- and his colleagues from the Max Planck
teractions among the biological, environ- Institute of Psychiatry. They found that
mental, and behavioral determination of patients with frequent episodic relapses
schizophrenia. Data are becoming available also had the best occupational adjustment
to go beyond the general outlines of a vul- at the time of long-term follow-ups. Simi-
nerability-stress model of schizophrenia to larly, in Chap. 12 on psychoeducatoional
an empirical framework that possesses pre- family therapy by Anderson, increases in
dictive Validity. Jobs, work, participation in relapses from 4% to 24 % were noted for pa-
social clubs, social skills training, familyed- tients from the 1st to the 2nd year of psycho-
ucation and survival skills training, and trai- social treatment, presumably because more
ning in problem solving have been identi- patients were holding jobs and involved in
fied in quantitative and objective studies as school and other kinds of normalizing work
having the power to reduce impairments in and educational activities. Thus, we might
social functioning and the frequency of re- view relapses as being temporary but neces-
Copying and Competence 205
sary costs for improved social functioning. arousal and low reactivity on electrodermal
In turn, strengthened social skills and fam- responses during the initial hospital period
ily coping may reduce the vulnerability of appear to predict higher symptomatology at
the individual at the behavioral level, en- the 3-month follow-up. Thus, through more
abling that person to be more resistant to frequent assessments in intensive follow-
subseqent stressful events and family ten- through studies, we may improve predic-
sion. tion of factors that influence the course of
As highlighted by this book, it is impor- schizophrenic disorders. Measures also
tant to extend our studies both longitudinal- need to be drawn from psychobiological
ly over time and intensively across relevant factors that may be markers or indicators of
biological, behavioral, and environmental the underlying vulnerability of schizophre-
variables. No longer is it sufficient to design nia; that is, factors that do not change when
studies that begin with initial assessments at symptoms change, but that remain fairly
point A and then recapitulate with follow- constant during pre morbid , symptomatic,
ups at 1, 2, 3, or 30 years later. We have and remitted periods.
gained knowledge from these follow-up or A frequent criticism of research on psy-
retrospective studies that assess patients at chosocial stressors in schizophrenia is its
long intervals; however, we will learn much lack of specificity to schizophrenia. Critics
more from intensive follow-through stu- who take this view appear not to realize that
dies, such as the one reported by Falloon nonspecificity of many protectors, stres-
in Chap. 14, which continuously and re- sors, and potentiators is integral to the vul-
peatedly rate biopsychosocial variables that nerability-stress model of illness and
influence the course of illness. This type of health. It is the nature of the interaction
intensive research design is exemplified by among nonspecific stressors, potentiators,
a current study being carried out at the and protective factors with specific psycho-
UCLA Clinical Research Center for the biological vulnerability that predict onset,
Study of Schizophrenia by Nuechterlein course, and outcome of schizophrenia. Psy-
and his colleagues (1984) who are studying chobiological vulnerability, perhaps in-
patients within 2 years of their first episode herited or influenced by congenital prenatal
of schizophrenia. The patients are followed or postnatal trauma, infection, or immuno-
for at least 2 years while they participate in logical events, determines specificity of ill-
a clinic where they are seen every 2 weeks as ness and its symptomatic impairments.
they come in for their medication evalua- However, nonspecific factors may be even
tions. Ratings of psychopathology and life more powerful in determining severity and
events are made every 2 weeks, and meas- course of illness. Moreover, factors that are
ures are taken of their autonomic psycho- nonspecific for diagnostic categories may
physiology and cognitive attention capabili- possess specificity for dimensions of course
ties every 3 months. Every year ratings are and outcome. The data reported on family
made of their home emotional climate factors in this volume are pointing the way
through the CFI. toward more specific and dimensional pre-
Preliminary results from this study indi- dictors of outcome in schizophrenia. For
cate that 3 months after discharge from the example, high expressed emotion may spe-
hospital, there is a strong trend for family cifically predict return of positive schizo-
"expressed emotion" (EE) to predict both phrenic symptoms, but not predict social
symptoms and poor occupational status. outcome. On the other hand, indices of di-
From direct behavioral observations made rect family interaction may better predict
of ecological variables during the index hos- patients' social adjustment. We must in-
pitalization, those young schizophrenics vestigate variables that not only predict
who show greater social interaction (i.e., relapse, but also other specific dimensions
talk with and listen more to other patients of outcome. We will undoubtedly discover
and staff and are in closer proximity to that some of our assessment instruments
other patients and staff) have a much better are better than others at predicting the vari-
rate of social functioning at the 3-month fol- ous domains of outcome of importance in
low-up point. At the autonomic level, high schizophrenia.
206 R. P. Liberman
Advances in Assessment
Improvements in assessment methods have direct observation of patients in natural, cli-
been highlighted in chapters of this volume nical environments (Licht, 1984; Paul and
and represent the most critical advances in Lentz, 1977). Methods of behavioral assess-
furthering our understanding of the vul- ment have permitted differentiation of di-
nerability-stress model of schizophrenia. agnostic groups, accurate predicaton of
Improvements in diagnostic and assessment short- and long term outcome, and evalua-
instruments have made generality and re- tion of the effects of different psychosocial
plicability of research on schizophrenia pos- treatment settings (McGuire and Polsky,
sible for the first time. Studies now can be 1982; Paul and Lentz, 1977; Paul, 1986;
compared across countries and cultures be- Alevizos, DeRisi, Liberman, Eckman, and
cause we share common criteria for diagno- Callahan, 1978).
ses of schizophrenia, and even more impor- Improvements in assessment help us to
tantly, common instruments for eliciting more specifically and efficiently identify
the symptoms of schizophrenia. The Pre- areas for intervention. We now can see as-
sent State Examination (PSE), the SADS, sessment, not as an isolated exercise in pa-
the SCID, and the DIS are now being used tient description, but as intertwined with
in many parts of the world (Andreason, treatment. The value of an assessment in-
1986). Results from studies in Europe are strument is enhanced if it enables a clinician
now comparable with those being done in to pick out problems and goals that can
centers in the United States. On both sides serve as targets for treatment. The instru-
of the Atlantic, investigators are using an ments described in this book for measuring
expanded approach to the assessment of family factors related to relapse - the CPI,
psychopathology and functional behavioral KPI, and AS codes - are excellent ex-
states that assumes that manifestations of amples of how assessment technology can
schizophrenia are heterogeneous and di- provide clinicians road maps for directing
verse. We no longer have to limit our focus treatment.
on characteristic symptoms of schizophre- The research reported in this book on the
nia as long as we take care to gather diag- role of expressed emotion in depression
nostic information very specific and reliable also reminds us that depression is a very
ways. We also have begun to better specify common problem for people suffering from
measures of social process and outcome schizophrenia, particularly in the post-hos-
variables. As illustrated by several chapters pitalization phase when the patient has re-
in this book, methods for measuring protec- constituted from first-rank symptoms. We
tive and potentiating variables within fami- can look forward to assessment instruments
lies are being developed in Germany, the that may help us to identify phase-specific
United States, and the United Kingdom; vulnerabilities to certain social stressors.
for example, the KPI (see Chapter 7), ex- We may discover, for instance, that individ-
pressed emotion, and Affective Style (AS, uals with schizophrenia who are in a de-
see Chapters 4 and 15) are bringing the role pressed phase of their illness may be more
of the family system into clearer focus. sensitive to relapse induced by critical com-
Instruments for measuring social adjust- ments made by workmates or family mem-
ment, social skills, and social competence bers. Identification of phase-specific vul-
are coming into use that will refine our ap- nerabilities can help us to refine and tailor
preciation of course and outcome at the so- our treatment programs to better fit pa-
cial and occupational levels and of treat- tients' needs. One very significant area
ment effects as well (Liberman, 1982). A which has benefited from advances in as-
very promising approach to measuring and sessment is the conceptualization of "re-
predicting social and behavioral status lapse."
comes from time-sampling techniques of
Copying and Competence 207
Operationalization of Relapse
Relapse in schizophrenia tends to be de- who it was agreed would fall into "relapse"
fined too broadly and loosely by most inves- and "no relapse" categories on clinical
tigators (Falloon, 1984). If we are to com- grounds. The criteria were then applied to
pare the results from studies and build on 28 schizophrenic patients who were partici-
each other's work in a truly scientific way, pating in a controlled clinical trial of psy-
then we need to know how each research chosocial and drug therapy. The patients'
group or team is actually defining and ope- ratings on the three psychotic scales at dis-
rationalizing relapse. Quantified scales for charge were used as the base line from
measuring changes in psychopathology which changes were assessed. Follow-up as-
have been developed at the UCLA Clinical sessments were conducted at 1, 3, 6, 9, 12,
Research Center for the Study of Schizo- 18, and 24 months. Monthly telephone calls
phrenia which have proven useful in relia- or visits were made by the project's social
bly assessing relapse as increases in symp- worker to ascertain whether a deterioration
toms exceed certain threshold criteria. The in functioning or increase in symptomato-
methods derive operational criteria from logy might be occurring. Any suspected in-
changes in severity of psychotic symptoms dications of a change in symptoms or func-
and signs as measured by standardized in- tioning triggered an immediate PAS evalu-
terview using the Psychiatric Assessment ation by a psychiatrist or psychologist. Of
Scale (Krawiecka, Goldberg, and Vaughn, the 28 patients in the study, 24 could be
1977) and the Brief Psychiatric Rating Scale rated by these criteria. The remaining four
(Overall and Gorham, 1962). patients had such high levels of persisting
symptoms at discharge that even rating a re-
lapse as an exacerbation of existing symp-
Psychiatric Assessment Scale (PAS)
toms could not be made. Interrater reliabi-
Criteria
lities obtained by two sets of interviewers in
Ratings on this scale are based on a brief 10- the United Kingdom and the United States,
to 20-min interview utilizing questions that utilizing the PAS, are shown in Table 2, and
elicit psychotic symptoms from the PSE. are acceptably high.
The PAS contains eight items which are
rated on a 0-4 scale of increasing severity,
and each scale point is operationally defin-
ed. For the purpose of defining relapse,
Brief Psychiatric Rating Scale (BPRS)
however, only the items assessing schizo-
Criteria
phrenic symptoms were employed, e.g.,
hallucinations, delusions, incoherence. Operational criteria for two categories of
The type I and II criteria presented in relapse were developed for an expanded
Table 1 were developed after extensive dis- version of the BPRS that included three
cussion and prior application of various new scales suitable for rating decompensa-
scoring strategies to a sample of patients tion of schizophrenic outpatients: bizarre

Table 1. Relapse Criteria Based on the PAS Psychotic Symptom Scale of Delusions, Hallucinations,
and Incoherence
Type I:
If a change from discharge rating occurs on only one of the three scales, a 2-point increase is designated
as a relapse, providing that a maximum severity score of 4 on that scale occurs. Thus, score increases
from 0 to 2 or from 1 to 3 would not be considered a relapse, but an increase from 2 to 4 would be a re-
lapse.
Type II:
A total increase of 3 points on one or more of the three scales is designated a relapse with the caveat
that single-point changes from 0 to 1 are not counted. (Zero represents symptoms absent, while 1 indi-
cates symptoms not clearly pathological. )
208 R. P. Liberman
Table 2. Interrater Reliabilities of the PAS Psychotic Symptom Scales

Kendal's coefficient of Pearson Rs for 2 raters


concordance W for five co-interviewing 51 patients
psychiatrists' ratings of 10
videotaped interviews

Delusions .83 .94


Hallucinations .78 .99
Incoherence .64 .85

behavior, self-neglect, and suicidality. Be- recover from an episode sufficiently to be


cause the BPRS was designed primarily for considered in remission. About 10% of
use with an inpatient psychiatric population first-admission patients and 22% of longer-
in psychopharmacology outcome studies, a term patients have such high persisting sym-
brief interview and anchor points applica- ptoms, even when they are discharged from
ble to an outpatient setting were developed the hospital, that there is no way that one
for its use with outpatients participating in could subsequently consider a rating a re-
longitudinal studies of course and outcome. lapse. These patients are near the top ofthe
The two types of relapse coded were: (1) psychopathology ceiling at all times. Thus,
psychotic relapse which is based on the core instead of using "all or none" qualitative
BPRS psychotic symptom scales of. hal- concepts of symptomatic status, it would be
lucinations, unusual thought content (de- better to adopt methods that permit meas-
lusions), and conceptual disorganization urement of psychopathology on a con-
and (2) other types of relapse, which signal tinuum. This is best done, as described in
gross impairments in the patient's func- Chap. 14, by frequent and repeated meas-
tioning and thinking but which are not as ures of the patient's key symptoms. This
clearly related to schizophrenic psychotic method of monitoring target symptoms
processes, that is, depression, suicidality, would also be useful for assessing needs for
self-neglect, bizarre behavior, hostility. changes in antipsychotic medication and for
The BPRS items that were used in these cri- determining the lowest dose consistent with
teria for relapse are presented in Table 3 sustained minimization of symptoms. Such
with their behavioral anchors and interrater an approach has been used for decades in
reliability coefficients. BPRS items are medicine where repeated measures of lab-
rated on a 1- 7 scale of increasing severity. oratory tests of organ function direct the re-
A rating of 6 (severe) or 7 (extremely sponsible clinician to treatment decisions.
severe) on the critical item signifies a re- There is no reason why objective and stand-
lapse. ardized ratings of patient's psychopatholo-
In future studies of schizophrenia, it may gy cannot enable mental health profes-
be advisable to avoid using qualitative sionals to titrate social therapies as well as
terms describing "states" of remission or re- drug treatment.
lapse. Many schizophrenic patients never

Research Instruments Have Clinical Valoe


There is the widespread, but misguided, clinicians in the field. I strongly diagree
view that assessment instruments, such as with that view. We denigrate the interests,
the Camberwell Family Interview (CFI) attitudes, and motivation of clinicians to
yield rich lodes of information but are only suggest that the CFI is too cumbersome and
useful in research. Because they take so difficult for them to learn. We are now get-
much time to learn and use reliably, it is felt ting to the point where our assessment in-
that they cannot be readily disseminated to struments are providing predictive and
Copying and Competence 209

Table 3. BPRS Scales and Behavioral Anchors Used to Define Various Types of Relapse. Interrater
Reliability is Expressed as Median Intraclass Correlational Coefficients.

Psychotic Relapse

Scale Rating Definition Reliability


item coefficient*
Unusual 6 Severe Full delusion( s) present with much preoccupation OR
thought many areas of functioning are disrupted by delusional
content thinking
.93
7 Extremely Full delusion( s) present with almost total preoccupation
severe OR most areas of functioning are disrupted by delusional
thinking
6 Severe Severeal times a day OR many areas of functioning are
disrupted by hallucinations
Hallucin- .97
ations 7 Extremely Persistent throughout the day OR most areas of
severe functoning are disrupted by hallucinations
Conceptual 6 Severe Speech is incomprehensible due to severe impairments
disorgan- most of the time
ization .73
7 Extremely Speech is incomprehensible throughout interview
severe
Other types of relapse
6 Severe Deeply depressed most of the time OR many areas if
functioning are disrupted by depression
Depression .90
7 Extremely Deeply depressed constantly OR most areas of
severe functioning are disrupted by depressive thinking
6 Severe Wants to kill self; searches for appropriate means and time
OR suicide attempt that is a potentially serious threat to
life with patient knowledge of possible rescue
Suicidality .97
7 Extremely Specific suicidal plan and intent (e.g., "As soon as _ _ _ ,
severe I will kill myself by doing X") OR suicide attempt
characterized by plan that the patient thought was lethal
or an attempt in a secluded environment
6 Severe Hygiene and eating potentially life-threatening, e.g., eats
and/or bathes only when prompted
Self- .78
neglect 7 Extremely Hygiene and eating life-threatening; does not eat or
severe engage in hygiene
6 Severe Unusual petty crimes, e.g., directing traffic, public nudity,
contacting authorities about imaginary crimes
Bizarre .84
behavior 7 Extremely Unusual serious crimes, e.g., setting fires, asocial theft,
severe kidnapping committed in bizarre fashion or for bizarre
reasons
6 Severe Has assaulted others but with no harm likely, e.g., slapped
or pushed others OR destroyed property, e.g., knocked
overfumiture, broken windows
Hostility .89
7 Extremely Has attacked others with definite possibility of harming
severe them or with actual harm, e.g., assault with hammer or
weapon
* Median ICC among the seven Developmental Processes BPRS raters.
210 R. P. Liberman
prognostic infonnation, at scientifically ac- because neuropsychological test batteries
ceptable levels, that would be highly bene- are in great demand and insurance com-
ficial to clinicians for guiding treatment. panies will pay for their cost. When patho-
Instruments have been carefully honed to logists began doing laboratory studies in
effectively elicit and rate high-quality infor- hospitals, fees for the tests could be charged
mation on problems and goals that could be that netted income to doctor and hospital;
chosen for treatment, the indications for they provided diagnostic and prognostic in-
certain types of treatment, and most im- fonnation that guided the treatment; and
portantly, assessments that reflect the pro- they could be analyzed and used to assess
gress that our patients are making over the progress patients were making. Labora-
time. tory tests were instituted, not as part of the
At some future time, we will have the so- practice of the nurse or general practition-
cial psychiatric equivalent of a thenno- er, but by new specialities of pathology,
meter or a panel of blood chemistry tests to clinical chemistry, and radiology. Radio-
aid our diagnosis and monitoring efforts. logists do not ask whether they should re-
We may ask the "family laboratory" for serve CAT scans for research only because
KPI or EE "readings" on our patient and they are so complex, so expensive, and so
family. These assessment instruments also difficult to teach people to use. No, they use
help to engage patients and families in them because they have scientific utility and
treatment, through their ability to produce they provide useful infonnation.
catharsis, to promote motivation, and to "Exportability" of an assessment proce-
make the family and patient more aware of dure is an example of the transfer of knowl-
the problems they face. Most people who edge. Many factors have been identified
have administered CFIs to families speak of that determine how, when, and why clinical
the powerful impact the interview has on research practices get adopted by other
the establishment of rapport and the feeling practitioners (Libennan, 1983; Libennan et
by the family members that they are being aI., 1986). One of the most important of
understood for the first time. Thus, moti- these factors is having an "internal champi-
vating and preparing families to participate on" , a person with positive informal or for-
in treatment is another strong justification mal status within an institution who is wil-
to incorporate these instruments into every- ling to fight for that innovation, to "raise
day clinical practice. the flag" and install the CFI, the KPI, or the
However, the most important of the fac- PSE. Once mental health professionals ex-
tors that will detennine whether any of our pand the clinical use of objective and scien-
assessment instruments will be adopted into tifically validated diagnostic and prognostic
psychiatric and psychological practice are tools, as radiologists and pathologists have
their profitability and their "exportability." already done, we will see hospitals compet-
Profitability is a major consideration for the ing with each other to hire a KPI technician
widespread professional acceptance of as- or a CFI interviewer to provide assessment
sessment instruments. Neuropsychology is services.
developing rapidly as a clinical subspecialty

Intervention Design for the Future


Specifying the relevant domains of func- intervention has worked very well in the
tional outcome for therapy, based upon as- area of sex therapy (Annon, 1974). In
sessments of patient and family deficits, is behaviorally oriented therapy for sexual
vital for setting goals in our treatment ef- dysfunctions, a certain proportion of cou-
forts. Planning for feasible and realistic out- ples only need a small amount of informa-
comes, consonant with the desires of pa- tion to correct their misbeliefs; for ex-
tient and relatives, will enable us to apply a ample, a single session with some reassur-
minimum-maximum approach to treat- ance and infonnation can produce improve-
ment. A minimum-maximum strategy of ment in 10% of the couples. Depending
Copying and Competence 211
upon their assets and defiats, more severely nestic CFI, which often yields an emotion-
disordered couples require more extensive ally satisfying catharsis. Many more fami-
counseling, adivice, and reassurance while lies will have to go through a survival skills
still others need more systematic behavioral workshop or an extended educational pro-
interventions such as training in sensate gram, perhaps sponsored by self-help or ad-
focus. A residual number of couples need vocacy groups. It is possible that well-de-
discrete behavioral training plus couple signed videocassettes could help to fill the
therapy that focuses on areas of their mar- need for family education, some of which
riage beyond the sexual sphere, such as could be carried out in the privacy of the
communication. home (Backer, Liberman, and Kuehnel,
We can make our family interventions 1985). Families with less coping skills will
more efficient by offering only so much as is have to go through intensive problem-solv-
desired and needed. Some families will do ing training and communication skills train-
very well with just a few sessions of educa- ing. Some families will require a combination
tional counseling or even a single an am- of family, individual, and group-therapies.

Modular Interventions
Cost constraints in the delivery of mental Medical Center in Los Angeles (Liberman
health service will move our interventions and Foy, 1983). The program focuses on
beyond minimum-maximum strategies to goal setting and problem solving. Modules
modular approaches that specify the ele- are provided for training these skills that a
ments of treatment that are best for certain patient lacks. A module is composed of a
patient needs. We know, for example, that category of skills falling within a major life
neuroleptics seem best for the positive domain and is constructed so that problem-
symptoms of schizophrenia. Workers in solving and interpersonal skills are taught
psychiatric rehabilitation also are develo- simultaneously.
ping methods for remediating specific social Each module is divided into separate skill
deficits through social skills training (Liber- areas with each area having specific behav-
man, Massel, Mosk, and Wong, 1985b). iors that are taught to achieve personal ef-
One example of a modular approach to fectiveness and competence. For example,
training social problem-solving skills to the module that teaches "medication self-
chronic mental patients comes from work at management" contains skill areas on (a)
the UCLA Clinical Research Center for learning about the benefits and side effects
Schizophrenia (Foy, Wallace, and Liber- of medications, (b) acquiring the skills of
man, 1983). Modules have been developed medication self-administration, and (c)
for training a variety of social and indepen- coping with the side effects of medication.
dent living skills, including personal hy- Patients proceed through each module in
giene, conversational skills, use of public sequence, starting with an "introduction"
agencies, job finding, leisure and recrea- that aims to highlight the values and advant-
tion, medication management, and money ages of the module to motivate subsequent
management. The modules are constructed participation. After acquiring requisite
to teach a patient specific functional skills, knowledge and skills in the "training"
to train the patient to solve problems that phase, patients learn how to gather the tan-
may be encountered while attempting to gible and social resources required to put
employ these new skills, and for practicing the skills to use. For example, to negotiate
the skills in vivo. medication side effects or dosage issues
Because most chronic mental patients with the prescribing physician, a patient
suffer from a spectrum of deficits in social must be able to use a telephone to make an
and independent living skills, a comprehen- appointment to see the doctor and find
sive yet modular program for remediating transport to take him to the doctor. After
these deficits has been designed and operat- solving such "resource management prob-
ed at a 500-bed Veterans Administration lems," patients anticipate "outcome prob-
N
I-'
N

(:i
:0
t::
cr'
(1)

Structured 3
Florid symptoms activities Intensive Il>
of schizophrenia psychopharma- ::I
graded
cotherapy
expectations

Specialized
behavior therapy
Sx's remit? token economy Increase dose
eod
social learning

Depot drugs
and
med education
Low dose drugs
0<
mtermittant
supportive, drugs
goal-oriented
psychosocial Ax 0'
drug-free trial
Vocrehab

Social skills
tramlng
Psychosocial rehab
and community support
program
(social prostheses)

Consider
drug-free
trial

Fig. 2. Decision tree for clinical management of schizophrenic disorders: drug and psychosocial
treatment strategies
Copying and Competence 213
lems" which might interfere with the suc- the physician at the appointment. Patients
cessful implementation of the skills in the can enroll in one or more of these modules,
natural environment. Thus, patients learn depending upon the extensiveness of their
how to deal with disappointing events, such deficits and the nature of the goals estab-
as the lateness or unpredicted absence of lished for their treatment.

Drug-Psychosocial Treatment Interactions


A modular approach to the treatment of given the benefit of optimal doses of neuro-
schizophrenia is diagramed in Figure 2. A leptic drug in the context of a supportive
decision-tree model is used to delineate the milieu - whether inpatient, day hospital,
choices available to the practitioner in im- home care, or residential care. Psychosocial
plementing treatment that is modular and treatment during the period of acute symp-
flexibly responsive to the specific needs and tomatology should be aimed at calming the
attributes of the patient, including the on- patient, buffering and reducing levels of so-
going effectiveness oftreatment. This treat- cial and physical stimulation and stress, and
ment model, then, guides the clinician to in- assisting the patient in integrating and
crementally provide additional modules of understanding the symptoms as part of an
intervention conditional upon the cumula- illness process. The most effective psycho-
tive impact of previous modules, and course social treatment, in any clinical locale, con-
of illness. tains elements of practicality, concrete
The flow chart depicted in Figure 2 also problem solving of everyday challenges,
integrates drug therapy with psychosocial low-key socialization and recreation, en-
therapy, thereby making the interactional gagement in tasks that are attainable, and
nature of treatment congruent with the specific goal orientation (Liberman, Fal-
multifaceted determinants of course and loon, and Wallace, 1984). It is important
outcome of schizophrenia. For example, that a positive therapeutic alliance - begun
patients with acute onset of schizophrenic during acute episodes and continued inde-
symptoms, good pre morbid adjustments, finitely into the aftercare period - occupy a
and low EE families could be considered for central position in the overall strategy for
drug-free psychosocial treatment if special- treating the schizophrenic patient, no mat-
ly structured and richly programed inpa- ter how much drug or psychosocial treat-
tient milieus were available (Carpenter, ment contributes to the overall plan. This
McGlashin, and Strauss, 1977; Paul and relationship can be with the prescribing psy-
Lentz, 1977). In one comparison study of chiatrist or with a paraprofessional case
intensive behavior therapy with custodial manager.
state hospital treatment, only 10.7% of the If the patient's symptoms respond to this
former patients required continuation neu- environmentally assisted drug regimen,
roleptic therapy compared with 100% of more specific psychosocial interventions
the latter patients (Paul and Lentz, 1977). can be considered depending upon those
Similarly, a supportive family-style residen- stressors in the environment and deficits in
tial treatment program, where only 8% of personal functioning that appear to play
the patients received neuroleptic medica- specific roles in relapse and community
tion, was clinically as effective as standard maladjustment. Thus, family intervention
hospital treatment with regular doses of can be offered when high EE, negative af-
medication. Furthermore, the patients fective climate. and communication de-
treated in the special-group home milieu viance are present in the family relation-
achieved more independent community ships. Similarly, vocational rehabilitation
living and superior vocational outcomes and social skills training can be provided
(Mosher and Keith, 1979). when deficits in these areas are interfering
Unless most or all of the prerequisites for with a patient's community adjustment and
a drug-free trial are present, a patient with quality of life. Family communication, em-
florid symptoms of schizophrenia should be ployment, and social skills may be consider-
214 R. P. Liberman
ed protective factors - at the personal and stems from the overarching importance of
environmental levels - against vulnerabili- individual differences in schizophrenia, dif-
ty to stress-linked relapse. ferences which are grounded in the wide
While space precludes a full annotation diversity of biological vulnerability, stres-
of the decision tree for clinical management sors, and protective and potentiating fac-
of schizophrenic disorders shown in Figure tors that together determine course and
2, one further point needs to be made. Psy- outcome of schizophrenic disorders. In-
chosocial treatment, as well as drug thera- deed, individual differences are found in all
py, should be long-term. It is clear from a medical disorders, and medical therapeut-
number of studies that the benefits accruing ics has been guided by an appreciation of
from psychosocial intervention do not be- and adherence to the special needs and re-
come apparent before 12 months and are sponses of the individual patient.
even greater at 2 years following initiation From yet another point of view, a mod-
(Liberman et aI., 1984). It is likely that in- ular approach to treatment makes sense. If
definite, if not lifelong, psychosocial sup- methods designed and tested in clinical re-
port, guidance, and training may be optimal search settings are to be "exported" to serv-
for most chronic schizophrenics. Since neu- ice settings and practitioners, the methods
roleptic drugs are most effective in main- must be adaptable to local conditions and
taining symptomatic improvement when constraints. Each treatment and rehabilita-
continued indefinitely, it should not be sur- tion system of care for chronically mentally
prising that psychosocial rehabilitation ef- ill individuals has its own strengths and
forts are similarly optimized by continuing weaknesses, its unique set of resources, and
care. The module in the flow chart labeled its political, social, and economic concerns.
"specialized behavior therapy, token econ- A comprehensive treatment program that
omy, and social learning" is purposely works in an urban setting may need con-
meant to be part of a closed loop. For siderable "retooling" before it can be used
refractory patients who resist most efforts in a rural setting. Thus, by dismantling com-
at deinstitutionalization, this arduous form prehensive programs into discrete elements
of intervention may have to be sustained for or modules, each treatment setting can
2 or more years. Such long-term commit- organize its own system of care that fits its
ment to a consistent and predictable location, organization, and patient popula-
psychosocial treatment environment has tion. Modularization of treatment for the
been shown to yield highly beneficial out- chronically mentally ill has already begun,
comes (Paul and Lentz, 1977; Banzett, including a resource book containing ele-
Liberman, Moore, and Marshall, 1984). ments of effective service for this important
The value of a modular and individualiz- group of patients (Liberman, Kuehnel,
ed approach to the combined drug and Phipps, and Cardin, 1985a).
psychosocial treatment of schizophrenia

References
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Subject Index

Acceptance 47, 79, 80, 82, 90 Camberwell Family Interview (CFI) 25. 26,
Acute phase 4 32. 38. 39.44. 51, 52. 59. 60. 61. 63. 73. 74.
- psychotics 111. 112 76.79,80.83.87,94.98,104. 110. 113. 158.
Adherence to medication 119 159,160,166.174,189.207,208,210.211,
Adopted children 3 212
Affection 47. 99 - Anglo-American 38. 39.41. 42. 43
Affective climate 193 Mexican-American 45
- communication 187. 190 - spanish 39
- relations 37 -. interrater reliability 63
- Style (AS) 52.53.55.57. 189. 190, 191. -. interviewing techniques 98
192.208 -, retest compliance 65
Aftercare X. 4 Catharsis 212
Aggression 102 Chicano 37
Alliance 124 Chronic patients 83
AMDP 82 Chronicity 2
Amotivation 151 Closeness 37
Anger 43.45.47.99.104. 113. 149 Cognitive overload 206
Anhedonia 197 Communication 99, 118, 119. 149. 174, 185.
Antiparkinsonian medication 150 187
Antipathy 43 - deficits 119
Antipsychotic medication 124. 125.210 - Deviance (CD) 104. 214
Anxiety 82. 135. 149 - skills 135
Apathy 105.151 - skills training 119. 125. 175
Approval 56 -. amorphous forms 112
Arousal 29 Community hostel 199
- hypothesis 165 - tenure 192
Assessment 119. 208 Competence 203, 205
Autonomic hyperarousal 206 Compliance 125. 126. 150. 156
- reactivity 203 Conceptual disorganization 210
Autonomy 31, 100 Conflict XI. 1. 118. 147
A voiders 136 Contact time 29
Conversational skills 212
Beck Depression Inventory (BDI) 87, 89 Convulsive treatment 2
Behavioral analysis 119. 174. 175 Coping XL 61. 82, 83,99, 101. 105. 119, 136.
- family therapy 173. 185 147.148.150.152.157.160, 185,187.191.
Belladonna 1 192, 203, 205, 206, 207, 212
Benefits 125 - skills 118
Benign criticism 53, 54 - styles 31. 46. 136. 139
Biobehavioral factors 203 Costs 184
- vulnerabilities 203 Cost-effectiveness 184. 185
Bizarre behavior 210 Crisis 149. 175
Blame 114. 135. 192 - intervention 113
Borderline 4 Critical 56
Brief Psychiatric Rating Scale (BPRS) 57. 179. - comments 39,43.44.45. 88. 90. 98. 161
209, 210 - comments. content analysis 44
Burnt-out 105 - remarks 32. 51. 52. 63
218 Subject Index
Criticism X. 26. 27. 45. 46. 51. 52. 53. 55, 57. - dual high 54
60. 79. 80, 81. 82, 83, 85, 89, 90, 99, 104, 123. - dual low 54
158. 165, 166. 189. 190. 192. 203 - high 27, 28, 29, 30. 31. 32, 33, 36, 41, 43,
- (CRIT) 65 45,46,47, 53, 55, 56, 57,59,60, 61, 63, 64,
65, 66, 67, 73, 74, 77, 85, 86, 88, 89, 90, 93,
94, 98, 99, 101, 102, 103, 104, 105, 113, 118,
Daily management 36
123, 147, 152, 155, 157, 158, 160, 161, 165,
DAS 90,93
188
Decompensation 209
- high, mothers 54
Deficit symptoms 112, 113
- low 27, 28, 29, 30, 31, 32, 33, 41, 43, 44, 45,
Deinstitutionalization 147.215
47, 53, 55, 56, 57, 60, 61. 64, 66, 67. 73. 74.
Delusions 32, 210
77, 85, 86, 88. 90. 93, 94, 98. 99. 100. 101.
Depression X. 32, 87. 89. 100. 208. 210
103, 104. 105. 118. 157, 158, 160
- endogenous 3
- modifications 95
Developing nations 35
- research 97
Diathesis stress model 123, 126, 187
Differential prognosis 35 - criticism 97
Disagreements 90 -. cross-cultural valididty 40. 41, 42
Discharge 14 -. determinants 103
-, development 33
-. psychopathological 16
Disengagement 151 -. ethnicity 42
Distress 43 -. fluctuation over time 103
Divorce 47 -. interactional correlates 51
Dominance 25 -. patient characteristics 42
Double-bind 104 -, psychophysiology 102, 118
-, response styles 31
Drugs antipsychotic 3
-, sociocultural context 47
-, antipsychotic X
- neuroleptic 4 -. socioeconomic status 41,42
DSM-III 109. 110. 111. 112 -. stability of 60
- Emotion, family 36
Dual-parent families 189. 190
- emotion. level of contact 25
Durations of looking 86
Dyadic Adjustment Scale (DAS) 89
Face-to-face contact 28.60. 74. 76. 155. 156.
158. 160. 163. 166
Economic benefits 184 - interaction 85. 86
Education 175 Familial commitment 47
- program 156, 158, 159, 160, 161, 166 - involvement 36
Educational program 131,212 Families mixed EE 54
- programs 109, 110, 112, 113, 114, 120 Familism 37
Electroconvulsive therapy 2 Family assessment 4
Electrodermal activity 29, 30 - assessment task 189
Emotinal overinvolvement 98 - bonds 45,47, 151
Emotional atmosphere 98 - burden 114.182
- Family Atmosphere (EFA) 79,80,81, - communication 119. 173
82.83 - Compliance Index (FCI) 72, 73
- overinvolvement (EOI) X. 25, 26, 27, 39. 53. - conflict 123
54. 55, 56, 57, 60. 63. 65. 68. 81. 83. 86. 98, - education IX, 117, 118, 119, 121, 126, 127,
99, 104, 123, 203 128, 129, 131, 133. 135, 136, 137, 138, 139,
- response 97 185, 206, 212
Empathy 100 - education program 120, 121, 123, 124, 134
Employment status 14 - education, live format 121
Ergotherapy 1 - education, mass media distribution 121
Ethnicity 38 - education, videotape format 121
Events 29 - etiology 123
Expectations 36, 123, 126, 135 - factors 208
Expressed emotion (EE) X, 5, 12,25,26.27, - functioning 30
28, 30, 32, 33, 36, 37, 38, 39,40, 41, 43, 51, - groups 119
52, 53, 57, 59, 61, 63, 65, 67, 73, 76, 77, 79, - interaction XI, 52, 80, 97, 98, 173, 203
85, 86, 89, 94, 97, 98, 102, 104, 105, 118, 119, - interaction, standardized situation 52
130, 147, 148, 149, 152, 155, 158, 159, 163, - intervention programs 113, 117
165, 166, 187, 190, 197, 207, 208, 211 - intervention. acute psychotics 113
Subject Index 219
- involvement 119 Interactions 30, 54, 85, 94
- life XL 97, 98, 104, 147 - direct 53, 98
- management 179, 180, 182, 185, 190 - pattern 90. 93. 94
- ombudsman 134 - style 93
- problem solving 175 - task 53, 57, 189
- programs XI Interactional behavior 52, 55
- stress 123 Intermittent medication, intermittent 193
- support groups 138 Intermorbid adjustment 33
- system 188 International Pilot Study of Schizophrenia
- tension 207 (IPSS) 13. 109
- therapy X, 76, 77, 83,117.119.130.148. Interpersonal boundaries 151
152 - skills 212
- therapy indirect 61 Interrater reliability 63
- therapy psychoeducational X. 60. 61 Intervention research 95
- transactions X Interviewing techniques 98
- treatment. models of X Intolerance 100
Flashbacks 111 Intrusion 189. 190
Flexibility 101. 126. 127 Intrusiveness 31. 46, 53. 55. 56, 57, 98.
Frankfurter Beschwerdebogen (FBF) 82 102. 192
Frustration 43,47.99,100. 102. 113. 133 Irritability 100
Functional analysis 174 Isolation IX. 157

Generational boundaries 151 Job finding 212


Gittelman-Klein scale 17,18.19 Justifications 90
Goal setting 212
Gobal Assessment Scale (GAS) 13. 14. 15. Kategoriensystem fUr Partnerschaftliche Inter-
18.20 aktion (KPI) 87. 208. 211
Goldstein scale 17. 18 Kin network 37
Group therapy 3 Knowledge interview 157. 158
Guilt 53. 123. 126. 133. 135. 138. 149
Leisure 212
Life events 30. 77. 114. 174. 192. 203. 207
Habituation 29 - goals 174
Hallucinations 32. 210 Lithium 3. 111
Haloperidol 13 Locus of control 45
Helplessness 99
Hemodialysis 3 Maintenance medication 29
Home environment 36 Mania 111
Hope 123. 131. 137. 139 Manics young 111
Hopelessness 133 Marijuana 111. 114
Hospital discharge 56 Marital adjustment 88
Hospitalization 2.4. 13. 14,27,31. 57, 81. - discord 151
110,137,147. 150 - interaction 88
Hostility X. 25, 26. 27. 39. 65. 79. 80. 88, 98. - satisfaction 86. 89. 90. 94
104.158.210 - therapy 161. 165
Humor 56 Medication 28.76.77. 97. 105. 125. 126, 129,
Hygiene, personal 100.212 131. 133, 134. 136. 137, 138, 148
- compliance 28, 76
leo 13 - depot 2
Inactivity 46. 151 - dosage 2
Independent living skills 212 - evaluations 119
Indifference 79. 80, 81. 82. 83, 105 - intermittent 193
Indignation 43. 45 - neuroleptic 11
Individual management 179, 180, 185 - self-management 212
Industrialized countries 35 - targeted 193
Information processing 203 -. benefits 125
Inpatient Multidimensional Psychiatric Scale Megavitamins 150
(IMPS) 13 Mental health education 105. 119
Insulin 2 - health-professionals IX
Integration, psychosocial 4 - illness 37
220 Subject Index
Mexican-Americans 36, 37, 38, 39, 41, 42, 43, Premorbid adjustment 12, 19. 31. 57. 99
45,47 - social adjustment 180
- familism 47 Premorbid personalities, poor 103
Minimum-maximum strategies 211, 212 Present State Examanization (PSE) 27, 38, 57,
Modeling 176 60,61,63,87,110,111,158,159,160,208,
Modular interventions 212 209,211
Money management 212 Preventive psychiatry 28
Moral treatment 1, 3 Pride 57
Morale 123 Primary caretaker X
Morbidity 178, 180, 182 Problem-Solving XI, 105, 125, 173, 174, 175.
- clinical 182, 185 180, 183, 185, 187, 192, 206, 212, 214
- family 184, 185 - deficits 119
- social 182, 185 - skills 100, 103, 118, 119,212
Munster Family Interview (Munsteraner - strategies (PSS) 192
Familienbogen, MFB) 79, 80, 81, 83 - training 119,175,176
Prodromal symptoms 2, 205, 206
Prognosis 12, 14, 124, 150
Negative feelings 176
- symptoms 3, 105, 112 Prognostic criteria 2
- scale 19
Neuroanatomy 124
Propranolol 3
Neuroleptic medication 2, 3, 4, 13, 29, 51, 60,
Protective factors 28, 36, 203
81,83,110,112,155,159,163,188,206,212,
Psychiatric Assessment Scale (PAS) 209
214
Psychoeducational family therapies 147
- depot 13, 69
- model 148
- medication continuous 69 - programs 111, 120, 122
- therapy 2 Psychopathology, at discharge 14
Neuroses 3 -,severity of 99
Nonresponders 11 Psychophysiological studies 29
Nonverbal behavior 80 Psychosis 1, 2. 3, 12, 13
- acute 109,110,113,114
Occupational disintegration 14, 20 - affective 15. 19,20,22, 112
Ombudsman 149, 150 -. atypical 12
Opium 1 - paranoid 13, 15
Outcome 14 -, psychodynamics of 3
-, poor 12 -, reactive 12
-, predictors of 12, 16 - schizoaffective 12, 13. 15, 19,20,22
Overinvolvement 43,45,77, 158, 161, 162, -, schizophrenic 19,22
165, 166, 190 Psychosocial treatments 60
Overprotectiveness 79, 80, 81, 82, 165 Psychotherapy 3, 4, 150
Overstimulation 83, 102, 150 - long-term 4
- supportive 13

Parental conflict 103 Quinine 1


Patients, chronic 13, 114
Personality change 14, 16, 19 Recovery period 126. 131, 137, 138
Pessimism 133, 138 - process 119, 123, 125. 132, 133. 136, 139
Pharmacotherapy 2, 185, 193 -, social X
- maintenance IX, X Recreation 212
-, depot 2 Rehabilitation IX, 3
-, long-term 2 - psychosocial 3
Phenothiazine 4 Rehospitalization 83
Phillips scale 12, 17, 18, 19 Rejection 47, 79, 80, 82
Placebo Treatment 2 Relapse X, XI, 2, 11, 12, 25, 27, 30. 32. 33,
Positive feelings 176 36, 52, 56, 59, 63. 67, 68, 70. 72. 73, 74, 77.
- remarks 26, 27. 98. 104 83.97,98,105,118.123,147,150,152,155.
- symptoms 212 159, 163, 164. 165. 187. 191.203.206.207,
Pre-illness relationship 99 208, 209
Predictor 14, 18,36, 67 - criteria of 64. 81, 84
- of relapse 98 - definitions 81
Predominance 80 - operationalization 209
Subject Index 221
-- predictors 12, 14, 18, 36, 67, 81, 98 - improvement 193
prevention 32, 193 - interaction 207
-- process of 85 - Interview Schedule 20
-- questionnaire 63 - learning 173, 215
- rate 2, 28, 29, 193 - management 20
- rate, in depression 32 - network 119,132
-- rates 28, 32, 69, 85, 86, 139 - reinforcement 176
-, risk for X, 29, 3 L 83 - role functioning 193
Relationship heterosexual 16 - skills 148,152,207,208
Relative-patient contact 28 - skills training 60, 151, 152, 206, 212, 214
Remission 210 - status 83
Residual symptomatology 57, 99 - stress 33
Resignation 79, 80 - support 100, 138
Role performance 152 - Support 5
- therapies 4
Sadness 43, 45, 149 - withdrawal 102, 112, 197
Schizophrenia 123 Sociocentric model 197
-courseof 11,51 Sociocultural processes 36
-, daily management 36 Socioeconomic status 41
- diagnosis of 121. 122, 131 Sociotherapy 13
-, dopamine hypothesis 124 Sorrow 43
- ethnopsychiatric models 44, 45 Stephens scale 12
-, etiology 123, 124 Stigma 45
-, family factors 36 Straus-Carpenter scale 19
-, genetic factors 123 Strauss-Carpenter scale 12, 17, 18
-, International Pilot Study (IPSS) 11 Stress XL 29, 30, 33, 36, 52, n 102, 103, 105,
-, misconceptions 121, 122 1 HL 123, In 133, 135, 137, 139, 147, 148,
-, misinformation 135 n
1 175, 185, 193, 203, 205, 206, 214, 215
-, neutrotransmitter theory 124 - level 137
-nuclear 112,114 management XL 129
-, outcome 11 Suicidality 210
- paranoid 3 Suicide 13, 15
-, sociocultural processes 36 Support 36, 37, 56
- spectrum disorders 32 - groups 119
-, symptoms 122 Supportive statements 56
Schizophrenics young 59, 60, 74, 76 Survival skills 120, 138
-, chronic 59 - skills workshop 119,121, 123, 126, 150,
Schizophrenogenic response styles 104 151, 206, 212
Schneiderian first-rank symptoms 110 Sympathy 43
Self-control 101 Systems theory 174
Self-disclosures 90
Self-neglect 210 Tardive dyskinesia 2
Self-statements negative 57 Target symptoms 179, 210
- positive 57 Targets of indifference 83
Sequential analyses 57 Tension 100,203
Shame 45 Therapeutic camps 196
Side effects 2,69,71, 105, 113,125,131,134, Therapy, behavioral 1
135,138,150, 163,212 -, pschodynamic 1
Silence 56 -, psychoanalytic 3
Single parents 190 Time budget 158, 160
Single-parent families 189 Token economy 215
Sleep 44 Tolerance 31, 99, 100
SociaL activities 180 Training 166
- adjustment 11, 12, 13, 15, 18, 20, 180, 208 Tranquilizer 125
- competence 208 Tranqulizer 124
- contact 164 Treatment, effectiveness 3
- control 101 -, inpatient 4
- distance 3 L 100 -, intermittent 2
- functioning 182, 205, 206, 207 -, long-term 2, 11
- impairment 105, 182 -, long-term effects 4
222 Subject Index
Treatment, low dose 2 Vaillant scale 12
-, maintenance 2 Vocational rehabilitation 214
-, neuroleptic 11 Vulnerability 30, 36, 61, 83, 102, 103, 118,
-, outpatient 4 148, 149, 205, 206, 207, 215
-, psychosocial 60 Vulnerability-stress model 203, 207, 208
Twins 3
Warmth 26, 27, 43, 52, 79, 80, 82, 90, 98, 104,
158
Understimulation 83 - remarks 51
Unemployment 14,46, 103, 105 Work 14, 180

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