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D. Ploog, F. Strian (Auth.), Prof. Michael J. Goldstein, Prof. Iver Hand, Dr. Phil. Habil. Kurt Hahlweg (Eds.) - Treatment of Schizophrenia_ Family Assessment and Intervention-Springer-Verlag Berlin H
D. Ploog, F. Strian (Auth.), Prof. Michael J. Goldstein, Prof. Iver Hand, Dr. Phil. Habil. Kurt Hahlweg (Eds.) - Treatment of Schizophrenia_ Family Assessment and Intervention-Springer-Verlag Berlin H
With contributions by
C. M. Anderson, B. Barbaro, R. Berkowitz, G. Buchkramer,
A. Cechnicki, L. J. Cozolino, B. Dulz, R. Eberlein-Vries,
I. R. H. Falloon, M. J. Goldstein, K. Hahlweg, I. Hand,
J. M. Hooley, J. H. Jenkins, M. Karno, L. Kuipers, J. Leff,
L. Lewandowski, R. P. Liberman, D. J. Miklowitz,
H. J. Moller, K. Nuechterlein, D. Ploog, F. Santana,
W. Schmid-Bode, H. Schulze-Monking, A. de la Selva,
A. M. Strachan, F. Strian, D. Sturgeon, A. Szymusik,
C. E. Vaughn, H. U. Wittchen, C. Wittgen, L. C. Wynne,
J. Zadecki, K. Zawadzka, D. v. Zerssen
Springer-Verlag
Berlin Heidelberg New York Tokyo
Prof. Michael J. Goldstein, Ph.D.
University of California, L.A.
Department of Psychology
1283 Franz Hall
Los Angeles, CA 90024
USA
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2119/3321-543210
Contents
Contributors VII
h~. ~
Introduction:
Treatment of Schizophrenia: Historical Aspects (D. Ploog and F. Strian) 1
Epilogue
17. Coping and Competence as Protective Factors in the Vulnerability-Stress Model
of Schizophrenia (R. P. Liberman) 201
A group of people are seated together in a tried to explain it to you, you wouldn't un-
room. Recently, they have shared two derstand,' and this went on and on in a big
important experiences - they have lived circle, nowhere, - no information at all!"
with a close relative, usually an offspring or The feelings of these relatives are not
spouse, who has been through an episode unique. Until recently, many relatives of
of a major mental disorder, most often of a schizophrenic patients experienced some
schizophrenic type, and they have also been form of rebuff by mental health profes-
participants in an experimental program sionals while their relative was treated as an
designed to assist them and their disturbed inpatient and little or no involvement in the
relative in modifying family patterns to aftercare process when the relative re-
foster rehabilitation. The experimental turned home. These attitudes of mental
programs involve maintenance pharmaco- health personnel reflected both the prevail-
therapy as well as a combination of family ing wisdom of the time that the family, be-
education and therapy. Since a number of cause of their pernicious impact, needed to
the relatives had experienced the problems be isolated from the patient and his treat-
of dealing with a mentally ill relative before ment, as well as a sense of helplessness
such a program existed, they were asked to concerning what information and advice
compare their current experiences with could be provided that would be useful and
earlier ones. An interviewer asket about helpful.
previous experiences with mental health The tendency to isolate and dissociate the
professionals when the relatives asked for relatives of severely disordered mental
information about their offspring or patients fit rather well with the treatment
spouse's mental disorder. One mother an- pattern existing in the United States and
swered: elsewhere from the end of World War II
Everything seemed to be kept such a dark secret until the early 1960s. Patients, when symp-
from the parents, from the people that are tomatic, were removed from their families
involved - whether that's the thing to do, I dont't for an extended inpatient stay. If and when
know, but I think that the parents need a lot of
support in whatever the program, the psychiatrist
released, they rarely returned to parental or
didn't give us that much. He was dealing with the spousal homes. Also, when patients were
patient but not with the family. released during this period, they frequently
had achieved reasonable levels of remission
A father from another family echoed these from their psychosis so that when they did
feelings of isolation, "We had the same return home relatives did not have to deal
problems, they would deal with the patient with active psychotic symptoms.
but not with the family at all. Everyone that The patterns of care which have evolved
our son went to, 1 mean, we went but that since the mid-1960s have forced both men-
was it. We were there, but we never saw tal health professionals and families of men-
anybody." The interviewer asked, "Did tal patients to rethink their respective roles.
you ask to see somebody?" The father Especially in the United States, the pattern
replied, "Yeah, you could see them, but of community care for schizophrenic pa-
they never had time to talk to you." tients has evolved into a two-phase ap-
Another mother from still another family proach in which a relatively brief inpatient
stated, "I first got absolutely nowhere, they stay is followed by extended aftercare in the
would tell me, 'You won't understand if 1 community. Because adequate transitional
X M. J. Goldstein et al.
living environments are rare, and even associated with a high probability of re-
when they do exist patients resist staying in lapse, actually alter the short-term course
them, patients frequently return to a family of the disorder? The first half of the book is
environment in varying states of partial re- oriented to reports which address these
mission. Examination of these family envi- significant questions.
ronments and the problems of reentry of a Although the focus of this book is on the
disturbed and frequently disturbing relative prognostic value of family attitudes, we
has revealed that families often experience have not ignored the significance of individ-
considerable difficulty in fulfilling the ual patient attributes as predictors of the
newly assigned role of primary caretaker. course of the disorder. Therefore a chapter
Even when families appear to cope well, discussing this issue is presented.
there is a notable impact on the mental The awareness that family members are
health status of relatives. In one study by increasingly responsible for the aftercare of
Hawks (1975), 50% of the relatives stated schizophrenic relatives and that specific
that their own mental health had been ad- attributes of the family environment may be
versely affected in the process of coping particularly pernicious has led to renewed
with the patient's mental disorder. interest in family intervention programs
Further research has indicated that atti- designed to support the family system, pre-
tudes expressed by the relatives toward the vent relapse, and foster the social recovery
returning mental patient are highly predic- of the patient. Many of these family inter-
tive of the likelihood that the patient will vention programs have utilized measures of
remain in the community 9 months after EE to identify the relapse-prone family
discharge from the hospital. The work of units in special need for treatment. Previous
Brown and his associates (Brown, 1959; attempts at using traditional family therapy
Brown, Birley, and Wing, 1972) followed with families of schizophrenics were not
up by Vaughn and Leff (1976) has gone be- successful or widely adopted. Further, these
yond informal clinical observation to pro- programs were, in the past, viewed as alter-
vide empirical evidence that those delete- natives to maintenance pharmacological
rious aspects of the family environment treatment. The newer models described in
associated with high risk for relapse could this volume are not based on such an either/
be specified and measured with standard- or conceptualization, and all, in fact, ac-
ized procedures. Their work on expressed knowledge the importance of antipsychotic
emotion (EE) revealed that relatives' atti- drugs as maintenance agents during the
tudes of criticism, hostility, and/or emo- posthospialization phase of treatment.
tional overinvolvement possess powerful These newer, experimental programs,
prognostic information about the likeli- which are frequently very pragmatic in
hood of relapse. These attitudes, assumed orientation, attempt to provide an addition-
to reflect ongoing family transactions, sug- al psychosocial dimension to aftercare be-
gest a particular sensitivity of the schizo- yond the protection against relapse provid-
phrenic patient to discriminable attributes ed by pharmacological agents.
ofthe family environment. In recent years, several models of family
While research on EE attitudes has been treatment have been developed, which at-
very provocative, there are still a number of tempt to include an educational component
unanswered questions about the construct. as 'part of a larger program of intervention
First, are EE attitudes associated with the for schizophrenic patients and their famil-
course of other psychiatric disorders such as ies. These models have been classified as
depression? Second, are the results gener- psychoeducational family therapies and
alizable to national or subcultural groups have been designed to help patients out of
other than the original English samples in hospitals and to return them to a productive
which the measure was developed? Third, life in the community. Working in tandem
are attitudes elicited during the interview with medication programs, they teach pa-
used to evaluate EE actually expressed in tients and families about the disorder and
family transaction? Finally, does thera- its management. Treating the family as a
peutic manipUlation of these EE attitudes, resource rather than as a stress, the pro-
Preface XI
grams focus on concrete problem - solving One chapter of this section describes a
and specific helping behaviors for coping unique intervention program for schizo-
with stress. These models recognize the phrenia developed by a clinical research
likelihood of a biological basis of the illness team from Poland. Since reports from
and the negative impact of stress on the Eastern Europe of innovative treatment
patient's ability to function. The underlying programs for schizophrenia rarely appear in
assumption of all psychoeducational family conjunction with those from Western Eu-
programs developed to date is that giving rope and the United States, the editors felt
families information about the nature of the that the inclusion of such a report would
disorder, along with specific suggestions for broaden the readers' appreciation of the
coping with it effectively, can decrease the diversity of family-oriented programs for
intensity and conflict inherent in family life schizophrenia which are emerging world-
and thus reduce the likelihood of (a) relapse wide.
in the index patient and (b) the emergence These topics were extensively discussed
of mental disorders in the previously non- and evaluated in two consecutive research
affected relatives. planning workshops, which were held on
These programs appear to have certain May 5-7, 1982 in San Diego, California
common components; (a) the establishment (USA) and on June 21-24, 1983 at SchloG
of a collaborative relationship between Ringberg, Bavaria (FRG). The first work-
therapist( s) and family members, (b) the shop was sponsored by the Department of
provision of information and support, and Psychology, UCLA, and the Office of Pre-
(c) the creation of highly structured pre- vention, Center for the Study of Schizo-
dictable environments in the treatment set- phrenia and Psychopharmacological and
ting and in the home. Somatic Research Branch, all of the Na-
While these commonalities exist, there tional Institute of Mental Health (NIMH).
are also substantial differences in the pro- The second workshop was sponsored by the
grams developed to date in terms of the Max Planck Institute of Psychiatry, Munich
type and detail of information provided (FRG).
about schizophrenia; the format of these Most of the chapters in this book repre-
family education programs (patients pres- sent papers that were presented at the
ent or not), the format of the extended fam- workshops. However, many of them have
ily therapy phase (relatives only vs family been altered or extended to reflect issues
and patient), the context of the extended raised during the formal and informal
family program (home vs clinic based), and discussions that followed each presenta-
the duration of these programs ranging tion. The epilogue in particular was written
from 6 weeks following discharge to to provide a comprehensive discussion of
programs lasting over 1 year. these various issues.
The variations in key dimensions of the It is difficult to characterize, on a printed
programs tested in controlled trials to date page, the emotional climate of both work-
warranted closer scrutiny to evaluate what shops. However, it was tremendously hear-
direction future research on preventive in- tening to us (as the organizers) to partici-
tervention programs for families with a pate in the sessions with professionals who
mentally ill relative should take. were not only extremely knowledgeable
The second half of the book deals with about their subject matter, but who were so
some of the more innovative family treat- enthusiastic in sharing their ideas and ex-
ment programs that have been tested in periences with each other with an absolute
controlled clinical trials in the United States minimum of defensiveness and posturing.
and Great Britain. In addition, we present There was a general feeling among the par-
some data concerning the impact of one ticipants that both workshops were a pro-
such program on family interaction, using foundly enriching experience.
procedures described earlier in this volume It is our hope that some of that flavor will
for measuring the correspondence between carryover to the reader and will stimulate
EE attitudes and directly observed family both clinical practice and research in the
behavior. difficult area of schizophrenia.
XII M. J. Goldstein et al.
References
Brown, G. W. (1959). Experiences of discharged Hawks, D. (1975). Community care. An analysis
chronic schizophrenic mental hospital patients of assumptions. British Journal of Psychiatry,
in various types of living group. Millbank Me- 127,276-285.
morial Fund Quarterly, 37, 105-131. Vaughn, C. E., and Leff, J. P. (1976). The in-
Brown, G. W., Birley, J. L. T., and Wing, J. K. fluence of family and social factors on the
(1972). Influence of family life on the course of course of psychiatric illness. British Journal of
schizophrenic disorders: A replication. British Psychiatry, 129, 125-137.
Journal of Psychiatry, 121,241-258.
The history of the treatment of schizophre- At the same time, however, it was pointed
nia reflects the continuing problems of es- out that in the case of an acute state of agita-
tablishing the etiology, even though today tion, hypnotics and narcotics "as a rule are
there is agreement that there has to be a of little use" (Kraepelin, 1899). Since schiz-
genetic disposition before schizophrenia ophrenic disorders were considered to be
will develop. As with all etiologically un- "the result of compound influences acting
clarified diseases, there are numerous etio- over a long period of time and gradually
logical hypotheses and therapeutic treat- having an increasingly profound effect," it
ment methods, with a corresponding dan- was not expected that rapid recovery would
ger of treatment methods being based on a result from administering drugs (Kahl-
priori assumptions or uncritical prag- baum, 1874). On the other hand, in the pre-
matism. Even the assessment of the effec- vious century psychiatry already had at its
tiveness of treatment, however, is closely disposal a wide variety of nursing methods
linked with valid diagnostic and assessment and psychological, social, and ergothera-
criteria, which have only recently become peutic approaches. An important part was
the object of intensive study (Carpenter, played by what was known as "moral treat-
Heinrichs, and Hanlon, 1981). ment," which evolved as early as the first
In the history of the treatment of schizo- half of the nineteenth century in England,
phrenia, the uncertainties with respect to France, and the United States and which
diagnosis, etiology, and therapy are re- essentially corresponded to present-day
flected not only in the relatively large varie- sociotherapy. Even before the turn of the
ty of therapy practiced but also in the century, "no restraint" treatment had not
marked influence of contemporary trends only shown itself to be of therapeutic value,
and cultural aspects, with swings between but the abandonment of rigorous restric-
biologically and psychologically biased ap- tions and physical restraint had also led to a
proaches. It can clearly be seen how fatal decrease in states of dramatic agitation.
any extreme position with regard to diagno- Committal was practiced to nurse the pa-
sis and therapy (e.g., a heavily biased genet- tient in an acute phase, but also to shield
ic or psychoanalytic approach) can be for him from provocative environmental influ-
both patient and psychiatrist. In between ences. In some cases, psychodynamic and
these extreme positions, however, there is a behavioral therapy approaches seem to
wide range of somatic and psychological have been anticipated. Kahlbaum, for ex-
therapies that individually and in combina- ample, wrote in 1874 that the goal of every
tion have without a doubt considerably therapy should be "to strengthen and rein-
ameliorated the situation of the schizo- force the ego and to save it from suppres-
phrenic patient. sion and disintegration." To that end, the
When schizophrenic psychoses first be- individual's premorbid imagination and
gan to be medically understood there were emotions were to be stimulated, without
virtually no somatic treatment methods however provoking the psychotic charac-
available. Opium in high doses, also bella- teristics. On the patient's return to his home
donna, quinine, and even digitalis were environment, the avoidance of emotional
tried (Griesinger, 1861; Kahlbaum, 1874). conflicts was considered to be of vital im-
2 D. Ploog and F. Strian
portance. An atmosphere of understanding prophylactic effect. In a review of 35 dou-
and patience would also help to prevent re- ble-blind studies already published, Davis
lapses. et al. (1982) established that long-term
It was not, however, these psychosocial neuroleptic therapy resulted in significantly
aspects, but the fact that schizophrenia in fewer relapses. Of the total of 3606 schizo-
the final analysis was considered to be an as phrenic patients investigated in the studies,
yet unclarified brain disease that was deci- 20% of those treated with neuroleptic drugs
sive for the further development of research but 53% of those taking placebos had re-
on psychoses. Kraepelin, in particular, called lapses over a 4- to 6-month time period. Pa-
for an intensive search for underlying neu- tients seemed to gradually relapse over
ronal mechanisms. Looking back at the time, that is, the number of relapses in each
somatic forms of treatment, it becomes month of the treatment appeared to be con-
clear that, with certain reservations, these stant. Neuroleptic drugs were shown to re-
represented the most important advances in duce the expected relapse rate by a factor of
the treatment of schizophrenic disorders. 2.5. When noncompliance patients were ex-
This is substantiated by a number of factors cluded, this factor rose to approx. 5.0. One
such as, for example, the improvement of year after hospital discharge, the average
the patient's condition, the shortening of relapse rate was 41 % for patients receiving
the hospitalization period, the decrease in active medication with a corresponding rate
the number of readmissions, and better of 68% for patients receiving placebo treat-
vocational and social reintegration. Thus, ment (Hogarty, 1984).
for example, the introduction of insulin and Maintenance treatment has been shown
convulsive treatment in the 1930s (Cerletti to produce significant results only when suf-
and Bini, 1938; Sakel, 1935) and the intro- ficiently high doses are administered. In a
duction of neuroleptic drugs in the 1950s group of schizophrenic patients treated
(Delay and Deniker, 1952, 1956) drasti- with low doses of Fluphenazin decanoate
cally, almost exponentially, reduced the (1.25-5.0 mg biweekly), the relapse rate
period schizophrenic patients spent in hos- was significantly higher than in a group
pital (Davis, Tanicak, Chang, and Kler- treated with a standard dosage (12.5-50.0
man, 1982; Meyer, 1984; Meyer, Simon, mg biweekly) (Kane, Rifkin, Quitkin, and
and Stille, 1964). In approximately the Klein, 1979a, 1979b). However, relapses
same way, it was possible to reduce the se- tended to be less severe when compared to
verity of the illness (Saarma, 1983). Since relapses in the standard dosage group
the introduction of neuroleptic therapy in (Kane et aI., 1983).
particular, the once common practice of Some words of caution are necessary with
physically restraining agitated patients as regard to long-term neuropleptic treat-
well as compulsory committals have be- ment. First, individual prognostic criteria
come the exception rather than the rule are still lacking. Consequently, treatment is
(Brill and Patton, 1959). In addition, not prescribed on the basis of individual
neuroleptic treatment has entirely replaced parameters but of overall criteria such as
insulin treatment, and electroconvulsive the chronicity of the disease (Gaebel and
therapy is practiced in only a limited num- Pietzcker, 1983). Second, drug-induced
ber of cases. The neuroleptic spectrum was tardive dyskinesia presents a serious prob-
broadened, and depot preparations in par- lem. It is estimated that after 4 years of
ticular have led to marked progress in long- neuroleptic treatment about 12% of the pa-
term treatment. It is now possible to identi- tients develope these largely irreversible
fy or predict side effects with greater cer- side effects (Kane, Woerner, Weinhold,
tainty, and in the case of long-term treat- Wegner, and Kinon, 1982). To avoid tar-
ment, it has become easier to balance out dive dyskinesia, new treatment approaches
desirable and undesirable neuroleptic ef- were tested, mainly low dose treatment
fects. (Kane et al., 1983) or intermittent treat-
It has recently been shown that in addi- ment in which the neuroleptics are with-
tion to their immediate antipsychotic effect, drawn and reintroduced whenever the pa-
neuroleptic drugs also have a long-term tient complains about prodromal signs
Introduction 3
(Carpenter, Stephens, Rey, Hanlon, and Although even before the turn of the cen-
Heinrichs, 1982; Herz, Szymanski, and tury and before Freud there was a great deal
Simon, 1982). Further research will show of interest in neurotic and hysterical disor-
how effective these approaches will be. ders as well as in appropriate therapeutic
Although in recent years new antipsycho- measures (such as hypnosis), this did not
tic drugs such as molindone, loxapine, and extend to psychotic disorders. It was quite a
pimozide have been developed, expecta- while before even Freud began to study the
tions in the field of psychopharmacology as problem of the psychodynamics of psycho-
to the development of selective or basically ses, and then he applied mechanisms that
new substances have not yet been fulfilled. he had established in connection with neu-
Except in a few specific cases, propranolol roses. [In the case of Schreber, incidentally,
seems to be mainly effective through poten- according to today's diagnostic criteria, the
tiation of neuroleptic drugs (Peet, 1981). patient was not suffering from paranoid
The effectiveness of lithium in schizophre- schizophrenia, but from endogenous de-
nia, excluding the schizoaffective forms, pression, probably of the bipolar type
does not yet seem to be sufficiently estab- (Koehler, 1981)].
lished (Delva and Letemendia, 1982), and The absence of a completely independent
hemodialysis in schizophrenia has been theoretical basis for psychoanalytic psycho-
shown to be a mistake (Skrabanek, 1982). sis therapy is probably also part of the ex-
No actual new alternatives to neuroleptic planation for the generally discouraging re-
treatment are yet in sight. sults. It can in general be seen that among
Parallel to somatotherapy, psycho- and the psychotherapeutic methods of treating
sociotherapeutic measures, though with schizophrenic psychoses, psychoanalytic
varying temporal and regional importance, methods have become much less popular
always played a part in the treatment of and methods aiming at the patient's social
schizophrenia. An early example of the ef- integration and rehabilitation have gained
fectiveness of social support comes from in importance. Here the treatment and
American psychiatry around the mid-nine- management of so-called negative symp-
teenth century (approx. 1830-1860) where toms is once again in the foreground.
"moral treatment" in small, open institu- Group therapy should not begin before the
tions where there was no discrimination acute psychotic symptoms have abated and
against the psychiatrically ill was also of at the same time should be oriented toward
considerable benefit to sufferers from schi- concrete everyday problems (Donlon,
zophrenia (Savino and Mills, 1967). These Rada, and Knight, 1973; O'Brien, et al.,
early experiences have been corroborated 1972). Even group therapy is more success-
anew by very recent, well-controlled trans- ful on the basis of neuroleptic drug treat-
cultural studies in which patients remain in- ment (Claghorn, Johnstone, Cook, and
tegrated in extended families and the mani- Itschner, 1974). In general, there will have
festations of psychosis are tolerated more to be a more precise definition of the tlrera-
readily by society. Here, the prognoses for peutically effective variables in psycho-
schizophrenic patients turned out to be therapy, situational therapy, and psycho-
more favorable in Nigeria, India, on the is- social rehabilitation. In their survey, Keith
land of Mauritius, and in Sri Lanka by com- and Matthews (1982) hence came to the
parison with Denmark and the USSR conclusion that all psychosocial therapeutic
(Murphy and Raman, 1971; Waxler, 1979; methods are generally assessed more opti-
World Health Organization, 1979). The re- mistically than the level of knowledge about
sults from research on twins and adopted them merits.
children are also of relevance in this con- On the other hand, a relatively clear pic-
text: on the one hand, they clearly show the ture is obstained by the methodologically
importance of genetic factors in the genesis excellent therapy studies in which the ef-
of schizophrenia, and on the other, do not fectiveness of neuroleptic and psychothera-
exclude the influence of environmental fac- peutic forms of treatment are compared.
tors (Kety, 1983; Kringlen, 1981; Rosenthal These comparative studies, however, are
and Ketty, 1968). mainly concerned with the effects treat-
4 D. Ploog and F. Strian
ment has on acute psychotic symptoms and roleptic treatment were noticeably better
only partially with long-term effects. In than those resulting from psychotherapeu-
these investigations the methodological tic treatment.
problems are not insignificant. A follow-up The question as to which of the psycho-
study, for instance, on a group of patients therapeutic methods used for schizophrenia
first described by Rosen (1947, 1953) gives the best results remains open due to a
showed that a large number of borderline lack of methodologically reliable studies as
cases had been included, and that in addi- well as of criteria for indicating when to
tion, in the long-term outcome of 75% of apply a particular method and establishing
the patients two to five readmissions had how effective it is. With regard to the effec-
occured (Horwitz, Polatin, Kolb, and tiveness oflong-term treatment, moreover,
Hoch, 1958). Results which significantly factors such as the length of time spent in
demonstrated the greater effectiveness of a the hospital (Glick and Hargreaves, 1979;
combination of psychotherapeutic and neu- Herz and Melville, 1980; Platt, Hirsch, and
roleptic drug treatment than of psycho- Knight, 1981), treatment on an inpatient
therapy unsupported by drug treatment basis only or a mixture of inpatient and out-
were obtained in a number of comparative patient treatment (Vanicelli, Washburn,
studies (e.g., Grinspoon, Ewalt, and Scheef, and Longabaugh, 1978), and partic-
Shader, 1972; Hogarty, Goldberg, and ularly the type of clinical aftercare (Linn,
Schooler, 1974a, 1974c; Hogarty, Gold- Caffey, Klett, and Hogarty, 1977; Stein and
berg, Schooler, and Ullrich, 1974b; Lind- Test, 1980) appear to be important.
berg, 1981; O'Brienet al., 1972). It is signif- Although a large number of valid com-
icant, for example, that in the study by parative studies demonstrated the necessity
Grinspoon et al. treatment with phenothia- of neuroleptic drug treatment, these results
zine proved to be no obstacle to psycho- are by no means an argument against psy-
therapy, but was rather found to result in chotherapeutic measures. It is far more a
better therapeutic cooperation and at the question of when which psychotherapeutic
same time fewer withdrawal tendencies on method should be used and with what aim
the part of the patient. Greenblatt, Solo- in view. The results of the comparative
mon, Evans and Brooks (1965), in a com- studies above all point toward therapeutic
parison of neuroleptic and social therapies, measures that can improve psychosocial in-
had already demonstrated that patients tegration and acceptance in the period fol-
who had no drug treatment in the acute lowing hospitalization. In this respect, the
phase of the illness were subsequently less situation today is in many ways analogous
able to profit from long-term psychothera- to the historical developments outlined
py than patients who had been treated with above.
drugs. Also on a pragmatic, rehabilitative level,
Particularly sobering results were ob- social therapy and aftercare today are es-
tained in the effectiveness studies of May, sential components of the treatment of schi-
Tuma, and Dixon (1981), where compari- zophrenia. This is particularly shown by the
sons were made between neuroleptic drugs, experiment in deinstitutionalizing schizo-
psychotherapy, and psychotherapy with phrenic patients since this was only achiev-
basic neuroleptic drug treatment and a con- ed without disastrous consequences for the
trol group with neither psychotherapy nor patient when he could be reintegrated into
neuroleptic drug treatment. Particularly family or social structures or received ap-
when long-term comparisons were made, propriate aftercare (Braun et al., 1981;
substantially better results were obtained Johnstone, Owens, Gold, Crow, and Mac-
for both the groups receiving drugs than for millan, 1981). The importance of including
the groups that had not received drugs. Al- the family in aftercare is clearly demon-
though the comparison is open to criticism strated by the family assessment and thera-
on account of the limited experience of py studies which are included in this vol-
some of the therapists, as well as the short ume. It is therefore not necessary to review
duration of psychotherapy, once again the these results. However, it must be pointed
long-term effects resulting from initial neu- out that it is not very likely that communica-
Introduction 5
tive structures are of specific significance in cial importance is something that still has to
connection with schizophrenia since social be proved. In any case, such concrete pat-
support also improves prognosis in other terns of interaction present an opportunity
psychiatric and even in most organic dis- of bringing about behavior changes without
eases (Strian, 1983, 1984). Whether the the individuals involved having to be bur-
particular sensitivity and anxiety on the part dened with unproductive questions as to
of the schizophrenic patient in response to a circumstances and persons in their environ-
critical, overprotective, and adverse envi- ment that might be responsible for the ill-
ronment ("expressed emotion") is of spe- ness.
References
Braun, P., Kochansky, G., Shapiro, R., Green- Delva, N. J., and Letemendia, F. J. (1982).
berg, S., Gudeman, J. E., Johnson, S., and Lithium treatment in schizophrenia and schizo-
Shore, M. F. (1981). Overview: Deinstitution- affective disorders. British Journal of Psychia-
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B., and Kinon, B. (1982). A prospective study O'Brien, C., Hamm, K., Ray, B., Pierce, J.,
of tardive dyskinesia development: Prelimi- Luborsky, L., and Mintz, J. (1972). Group vs.
nary results. Journal of Clinical Psychophanna- individual psychotherapy with schizophrenics.
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G., Sarantakos, S., Schiebel, D., and Ramos- nic? Neuropharmacology, 20,1303-1307.
Lorenzi, J. (1983). Low dose neuroleptic treat- Platt, S., Hirsch, S. R., andKnight,D. C. (1981).
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phrenic disorders. In: L. Grinspoon (Ed.), Psy- Rosen, J. N. (1953). Direct analysis. Selected
chiatry 1982 (pp. 166-178). Washington, DC: papers. New York: Grune and Stratton.
American Psychiatric Press. Rosenthal, D., and Kety, S. S. (1968). The trans-
Kety, S. S. (1983). Mental illness in biological mission of schizophrenia. New York: Perga-
and adoptive relatives of schizophrenic adop- mon.
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Psychiatry, 140,720-727. Schizophrenen [Study of results of treatment in
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Introduction 7
Sakel, M. (1935). Neue Behandlungsmethode Strian, F. (1984). Medizinische Aspekte von
der Schizophrenie. [A new treatment method Sozialangst und fehlender mitmenschlicher
for schizophrenia]. Wien: Perthes. Hilfe. Medizinische Klinik 79, 278-280.
Savino, M., and Mills, A. (1967). The rise and Vanicelli, M., Washburn, S., Scheef, B. J., and
fall of moral treatment in California. Journal of Longabaugh, R. (1978). A comparison of usual
the History of the Behavioral Sciences, 3, and experimental patients in a psychiatric cen-
359-369. ter. Journal of Consulting and Clinical Psycho-
Skrabanek, P. (1982). Haemodialysis in schizo- logy, 46, 87-93.
phrenia: Deja vu or idee fixe. Lancet, 1, Waxler, N. E. (1979). Is outcome forschizophre-
1404-1405. nia better in the nonindustrialized societies?
Stein, L., and Test, M. (1980). Alternative to The case of Sri Lanka. Journal of Nervous and
mental hospital treatment. Archives of Gener- Mental Disease, 167, 144-158.
al Psychiatry, 37, 392-411. World Health Organization. (1979). Schizophre-
Strian, F. (1983). Angst. Grundlagen und Klinik nia: An international follow-up-study. Chiche-
[Fear. Bases and clinical practice]. Berlin Hei- ster: Wiley.
delberg New York: Springer.
A. Prediction of the Course of Schizophrenia
I. Patient Attributes
Our first study was a 5- to 6-year follow-up viously been admitted to a psychiatric hospi-
on about 100 patients who had been treated tal before entering the Max Planck Institute
as inpatients in the Max Planck Institute of (index admission). The sample was almost
Psychiatry (Moller et al. 1981 a, b, 1982 a, equally divided between men (49%) and
b). The study was performed using standard- women (51%). Sixty-six patients (82%)
ized assessment procedures, among them were 40 years old or younger, and only one
the Inpatient Multidimensional Psychiatric patient was over age 60. Only 22% were
Scale (IMPS) (Lorr, 1974) and the clinical married. Treatment consisted of neurolep-
self-rating scales (von Zerssen, 1976) to de- tics (mostly haloperidol, in individualized
scribe the psychopathological state and the but not high dosages), supportive psycho-
Global Assessment Scale (GAS) (Spitzer, therapy, and sociotherapy. Hospitalization
Endicott, and Fleiss, 1976) for describing was not longer than 3 months for 92% ofthe
the global outcome at follow-up. patients with only 8% staying for more than
At discharge 5 years earlier, the clinical 4 months. Usually 1-2 weeks before dis-
diagnosis was based on the leD classifica- charge, the oral neuroleptic medication was
tion. Of all the patients, 77% met the leD changed to an intramuscular depot neuro-
description for schizophrenia (leD 295; pa- leptic. The sample seems comparable to the
tients with schizo affective psychoses: leD schizophrenic population of university clin-
295.7 were excluded from this study) and ics, but not to that of county hospitals where
23% the leD descriptions for other types chronic patients are overrepresented. It
of paranoid psychoses (leD 297, 298.2, also appears comparable to the IPSS sam-
298.3,298.9). At follow-up, seven patients ple, which excluded chronic patients (with
had died, five of them by suicide. Sufficient psychotic symptoms of more than 2 years
follow-up data for the statistical analyses duration in the 5 years before index admis-
could be obtained from 81 patients, for sion or hospitalized more than 3 years).
three of them only by relatives. At follow-up, 44% of the patients showed
This sample (n = 81) included patients serious psychopathological symptoms and/
with their first lifetime episode (55%) or re- or disturbances of social adjustment, indi-
turn of the disorder at index admission. cated by a score below 50 on the GAS; 31 %
Sixty percent of the patients had never pre- were below a GAS score of 40, which means
Information from
Patients Relatives
Level of functioning No. % No. %
100-91 No symptoms 8 10 5 10
90-81 Transient symptoms 8 10 0 0
80-71 Minimal symptoms 4 5 5 10
70-61 Some mild symptoms 14 18 11 23
60-51 Moderatesymptoms 8 10 1 3
50-41 Any serious symptomatology 10 13 6 13
40-31 Majorimpairment 15 19 11 24
30- 21 Unable to function 9 12 8 17
20-11 Needs some supervision 0 0 0 0
10-1 Needs constant supervision 0 0 0 0
Not classifiable 2 3 0 0
Total 78 100 47 100
14 H. J. Moller et al.
according to the GAS definition that hospi-
talization would be expected if the patient
was not already hospitalized. During the
follow-up period, 34% of the patients were
unable to work for more than 1 year; 58%
had to be readmitted to a psychiatric hospi-
tal, 10% for more than 1 year. At follow-
up, 16% were living in a nursing home and
6% were psychiatric inpatients (Table 1).
Correlation analyses between the GAS
score and other outcome criteria demon-
strated that the GAS score best reflects the
general outcome (Table 2). Therefore, it
0\
V)
was chosen as the main criterion for the
o analysis of predictors. Among approxima-
I tely 40 potential predictor variables tested
in a product moment correlation analysis, a
O","N\O ,....;
number of variables proved to be statistical-
000"'""'"
""';000
V)
o
ly significant (P < 0.05) predictors of global
outcome (Table 3). The best predictors
(r > 0.35) were: duration of occupational
O<'l","NN
disintegration (inability to work, unemploy-
o \0\0 \0 V)
""';0000 ment) during the 5 years preceding index
admission, impairment of working ability in
the year before index admission, personali-
00\0\<'lV)""';
ty change before index admission, poor psy-
or-\Or-V)V)
""';00000 chopathological state on discharge, and the
self-rating factor of paranoid tendencies at
discharge. High scores on these variables
000","0\000\<'l
were correlated with a poor global out-
o \0 V) r- 00 <'l V)
""';000000 come. Besides these variables, some others
correlated significantly with the outcome
criterion, but mostly the percentage of ex-
ONr-r-Oo\\O""'; \0
plained variance was below 10%.
Or-<'lNV)V)N","
""';0000000
V)
o Most of the predictors found in our study
have already been mentioned in the litera-
ture dealing with the prognosis of schizo-
phrenia. Among those variables that
proved to be of greatest prognostic signifi-
cance in our own study, occupational dis-
integration (employment status) before in-
dex admission was a strong predictor in stu-
dies by Strauss and Carpenter (1974,1977).
The prognostic value of the psychopatho-
logical state at discharge was emphasized by
Renton et al. (1965), Affleck, Burns, and
Forrest (1976), and Wittenborn et al.
(1977). A personality change, especially in
the sense of a lack of emotion, is another
predictor that has been described by many
authors (Vaillant, 1964; Lindelius, 1970;
Stephens, 1970; WHO, 1979).
Analyses of correlations between the
predictor variables and other outcome
Outcome and Prediction of Outcome in Schizophrenia 15
Table 3. Predictors of Global Outcome (GAS) (n = 74-78; for Self-Rating Factors, n = 45-50)
Correlation
Predictors of global outcome (GAS) coefficient
(-) Higher socioeconomic status of the parents .25
(-) Premorbid working dysfunction .27
(+) More advanced age at first manifestation .28
(+) More advanced age at first hospitalization .23
(+) Precipitating factors before first manifestation .28
(-) Duration of psychiatric hospitalization (5 years before index admission) .27
(-) Duration of occupational disintegration (5 years before index admission) .38
(+) Lasting heterosexual relationship .28
(- ) Impairment of working ability (1 year before index admission) .39
(-) Personality change (1 year before index admission) .42
(-) Diagnosis of schizophrenia .25
(- ) Poor psychopathological state at discharge .35
(-) IMPS superfactor of organic syndrome * at discharge .30
(- ) IMPS superfactor of depressive-apathetic syndrome" at discharge .24
(+) Ratio of amelioration of the IMPS superfactor of psychotic excitement .28
(-) Self-rating factor of paranoid tendencies at discharge .39
(+ ) Ratio of amelioration of the self-rating factor of paranoid tendencies .40
( + ) = good prognosis; ( - ) = poor prognosis
, IMPS factor "retardation and apathy" + IMPS factor "disorientation";
** IMPS factor "anxious depression" + IMPS factor "retardation and apathy" + IMPS factor "im-
paired functioning"
criteria revealed that the prognostic signifi- psychoses (leD 297, 298.3). In this inves-
cance of one variable for the GAS score did tigation, the follow-up period was 5-8
not necessarily apply to other outcome cri- years.
teria (Table 4). Likewise, a variable that is At follow-up, two patients had com-
a good predictor for one outcome criterion mitted suicide. Sufficient information for
may not be predictive for the outcome on the statistical analyses could be obtained
the GAS. The inclusion of variables that are from 46 patients: 32% of them had never
predictive for other outcome criteria, but been admitted to a psychiatric hospital
not for the GAS, expands the number of prior to their treatment in the Max Planck
predictors. Institute (index admission); 59% of the pa-
tients were male, 41 % female; 83% were 40
years old or younger. Only 24% were mar-
Outcome and Predictors, Second Sample
ried.
Using partially the same assessment The outcome results are rather similar to
procedures, a second follow-up study the first sample; concerning the longitudi-
(Schmid-Bode and Moller, in preparation) nal criteria, they were somewhat worse,
on patients of the same diagnostic group perhaps due to the longer follow-up period.
was performed to replicate the findings con- Of the patients, 33% showed serious psy-
cerning outcome and predictors, especially chopathological symptoms and/or disturb-
the findings on prognostic scales (see p. 17) ances of social adjustment (GAS score be-
on the one hand and to compare the out- low 50); 26% were rated on the GAS below
come results with affective psychoses and 40, indicating that they needed hospital
schizoaffective psychoses on the other (see treatment; 49% of the patients were unable
p.19). This sample included 61 patients who to work for more than 1 year during the fol-
had been treated in the Max Planck Insti- low-up period; 81 % had to be readmitted to
tute of Psychiatry. Most of the patients (55) a psychiatric hospital; and: 30% were treat-
were diagnosed as schizophrenics (without ed for more than 1 year as psychiatric in-
schizoaffective psychoses) and only six as patients during 5 years after index treat-
suffering from similar types of paranoid ment. At follow-up, 26% were living in a
16 H. J. MOller et al.
Table 4. Product-Moment Correlations of the Most Important Predictors (Correlations with the G AS-
Score r > 0.35). Sample I (n = 74-78); Sample II = Replication Sample (n = 43-46)
nursing home or were psychiatric inpa- sexual relationship. Some others were not
tients. replicated as predictors concerning the
As to the predictors of outcome, some GAS score, e.g., age at onset of the illness
findings could be replicated. Of special in- and age at first psychiatric hospitalization,
terest is that the duration of professional self-rating of paranoid tendencies at dis-
disintegration during the 5 years before in- charge, personality change before index ad-
dex admission and the psychopathological mission, and depressive-apathetic syn-
state at discharge again were found among drome at discharge. Thus, the known fact
the best predictors (Table 3). Also, some that results of predictor analyses depend in-
other characteristics again could prove their tensively on the specific characteristics of
predictive value, such as a lasting hetero- the sample becomes obvious.
Outcome and Prediction of Outcome in Schizophrenia 17
Optimizing the Predictive Possibilities by Kokes et al. (1977), apart from the fact that
Prognostic Scales we used an inverse scoring for the Strauss-
Carpenter scale. The data for these scales
To increase the outcome variance explain- had to be gathered from the records so that
ed by single predictors and to make the pre- in this respect the study is complicated by
diction more stable concerning different the typical problems of retrospective ap-
samples and different outcome criteria, proaches. Fortunately, the records of the
prognostic scales were applied (Moller, Psychiatric Department of the Max Planck
Schad, and Zerssen, 1984a, 1984b). Four Institute of Psychiatry (MPIP) are rather
scales communicated in the literature were well structured and informative so that in
tested concerning their predictive validity: most cases the necessary data were availa-
1. The Gittelman-Klein scale of prem- ble. In this context, it has to be mentioned
orbid adjustment (Gittelman-Klein and that some of these scales, such as the Phil-
Klein, 1969) lips scale, were developed with the special
2. The Phillips scale of premorbid adjust- aim of making it possible to obtain an evalu-
ment (Phillips, 1966) in the short version ation on the basis of data from case records.
of Harris (Harris, 1975) To avoid a potential bias, the evaluation of
3. The Goldstein scale of pre morbid adjust- the records was made by a psychiatrist who
ment (Rodnick and Goldstein, 1974) was not informed about the outcome data
4. The Strauss-Carpenter prognostic scale of the patients.
(Strauss and Carpenter, 1974) In addition, four new prognostic scores
All these scales were used in the version were developed and tested concerning their
published in the appendix of the review by predictive validity. Based on the results of
40
30
20
10
years). There were more female patients patients with affective psychoses, and 33%
among affective psychoses (57%) and schizo- of schizophrenics. In the worst group
affective psychoses (68%) (schizophre- ("completely unable to work or help with
nia: 41 % females). In addition, the schizo- the housekeeping"), only schizophrenic pa-
phrenic sample was compared concerning tients (24%) were found. The duration of
social adjustment to 46 nonpatients occupational disintegration during the fol-
matched for sex, age, and marital status low-up period exhibited a similar tendency:
from a random sample of 499 persons of the the schizophrenics had the longest duration
general population who were assessed by of inability to work.
the same standardized method. To measure These results might be partially biased by
social adjustment, a modified version of the the discrepancies of sociodemographic vari-
social interview schedule (SIS) (Clare and ables mentioned above. In this respect, the
Carins, 1978; Faltermaier, 1982) was ap- comparison of SIS data between patients
plied. and matched controls attracts more confi-
At follow-up, 77% of the patients with dence. Furthermore, the structured SIS al-
affective psychoses were married compared lows a more detailed view on social adjust-
to 17% of schizophrenic and 27% of schizo- ment (Figure 3). The objective conditions
affective patients. The global level of func- of occupation (for the 50% of schizophrenic
tioning as measured by the GAS also show- patients who were still working or studying)
ed marked differences between the diagnos- and the opportunities for social contacts
tic groups. The schizophrenic patients and leisure activities were not markedly dif-
were, on an average rated in the lower half ferent for schizophrenic patients and
of the 1oo-point GAS score range, whereas matched controls. Regarding their social
patients with affective of schizo affective management, however, significantly more
psychoses were more frequently repres- schizophrenic patients had marked or severe
ented in the upper range of scores (Fig- problems in occupation, social contacts,
ure 1). and leisure activities. Subjective dissatisfac-
Impairment of working performance in- tion was also more frequently expressed by
cluding study and housekeeping during the schizophrenic patients, but here the dif-
last year of the follow-up period can be seen ferences were not as marked. This discrep-
from Figure 2. No impairment was shown ancy between the ratings on management
by 95% of schizo affective patients, 71% of on the one side and the ratings on satisfac-
Outcome and Prediction of Outcome in Schizophrenia 21
1::%1
80
70
60
50
40
30
20
Fig. 2. Impairment of working 10
performance 5-8 years after dis-
charge.
o ~~~ ______ ~~ ____ ~~ ____ ~~ ______ L L_ __ _ _
Social Leisure
Occupation contacts activities
%
60
50
Problems .0
in social 30
management
20
10
Social Leisure
Occupation contacts activities
%
60
50
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II. Family Attributes
2. An Introduction to EE Measurement
and Research
J. M. Hooley
Introduction
Expressed emotion (EE) is currently one of provided good evidence that the construct
the most important measures of family of EE is both valid and can be measured
functioning available to clinicians and re- reliably. Moreover, not only do familial
searchers working with schizophrenic pa- levels of EE predict relapse in schizophre-
tients. Based as it is on the number of criti- nic patients, but EE also appears to have
cal comments and level of emotional overin- some predictive validity for other psy-
volvement spontaneously expressed by a chiatric populations, specifically the depres-
relative over the course of the Camberwell sed. This introductory chapter will discuss
Family Interview (CFI) , the EE rating is the development of the EE construct and its
considered to reflect the attitude of the re- measurement and focus on some of the re-
lative toward the psychiatrically ill family search which has made an important contri-
member. bution to our current understanding of this
Research conducted in recent years has valuable concept.
An Historical Perspective
The initial stimulus for the development of high levels of contact with their families.
the EE construct came originally from work That spending a lot of time with close re-
begun in England. Working with more than latives might not necessarily be beneficial to
200 discharged male psychiatric patients, schizophrenics was a rather unusual find-
most of whom had a diagnosis of schizophre- ing, and in subsequent research Brown
nia, Brown and his collegues (Brown, 1959; (Brown, Monck, Carstairs, and Wing,
Brown, Carstairs, and Topping, 1958) ob- 1962) attempted to document more preci-
served that the type of living group to which sely those aspects of living situations
patients were discharged seemed to be as- having most impact on patient outcome. In
sociated with how well or how poorly they a later study, which again used male schizo-
fared upon return to the community. Of phrenics, Brown employed a prospective
particular interest was the finding that pa- design and, in addition, interviewed the key
tients who returned to live in lodgings or female relative of each patient on three dif-
with siblings were more psychiatrically ferent occasions. Levels of "emotion ex-
healthy over the course of the subsequent pressed," "hostility," and "dominance"
year than patients who were discharged into were assessed for patients and relatives, al-
the parental or matrimonial home. Inter- though later analyses revealed only the rat-
estingly, it was also noted that the amount ings made for relatives to have any predic-
of time patients spent in contact with their tive utility. Briefly, the results showed that
relatives was another important factor relat- patients who returned to homes high in hos-
ed to outcome; patients who had only limit- tility or EE (high emotional involvement
ed contact with their relatives were less like- homes) were more likely to suffer a psychia-
ly to suffer a relapse than patients who had tric relapse over the course of a 1-year fol-
26 J. M. Hooley
low-up than patients who returned to live in assessments made and establishing reliable
low emotional involvement homes. techniques of EE measurement (Brown
This confirmation of the original finding and Rutter, 1966; Rutter and Brown,
was encouraging and, over subsequent 1966). The result was the development of
years, Brown and his co-workers began to the Camberwell Family Interview, describ-
focus attention on improving the interview ed below.
Measuring EE
Family levels of EE are assessed by means that's probably because I'm a rather intoler-
of the CFI, a nonschedule, standardized in- ant person." In these cases there is no
terview typically taking between 1 and 2 h dicrect blame of the patient and the remark
to carry out. The interview is conducted is consequently not considered critical.
with the patient's closest relative and is au- Remarks which are rated as critical be-
diotaped for later coding. Over the course cause they involve changes in the speed, in-
of the interview, the relative (who is most flection, or pitch of voice of the speaker
frequently a parent or a spouse) is asked cannot be retracted in this way, however.
questions about the emotional climate in While it is not easy to convey the essence of
the home in the 3 months prior to the pa- critical remarks which involve tone change
tient's admission to the hospital. Informa- using printed examples, the following il-
tion is obtained about the events which had lustration, taken from Kuipers (1979), is
taken place during this time and about the helpful.
relative's feelings toward the patient and his The words 'every morning he goes to buy the
or her condition. It is on the basis of the newspaper' have innocuous content but can be
emotions expressed while talking about the said in a variety of ways to give different emo-
patient that ratings of EE in the relative are tional meanings. If they were intended to be criti-
made. cal, this would be conveyed by writing stress
A total of five different ratings are made. marks - 'every morning he goes to buy the news-
paper.'
These include criticism, hostility, emotion-
al overinvolvement, warmth, and positive Emphasis on the first word thus conveys cri-
remarks. While only the first three of these ticism - in this example, criticism of the
have featured prominently in the literature regularity with which the patient goes out to
thus far, brief descriptive details of all five buy the newspaper.
scales will be given below.
Hostility:
Unlike criticism, which, as can be seen from
Criticism: the above illustration is situation specific,
Criticism is the sum total of critical remarks hostility involves a greater generalization of
the relative makes about the patient during negative feeling and usually includes re-
the course of the interview. Remarks are marks critical of the patient himself rather
judged as critical on the basis of (a) their than of his particular actions or behaviors.
content or (b) voice-tone changes. For a re- Examples of hostility include generalized
mark to be coded as critical on grounds of criticism (e.g., "He is stupid. Everything he
content, there has to be clear evidence of does is stupid. ") or of direct rejection ("It's
dislike, disapproval, or resentment on the just unbearable sometimes to be with her").
part of the speaker, e.g., "It's annoying While criticism is measured by simplyrecor-
coming in at night and finding breakfest ding the frequency of critical remarks the
things still on the table." A respondent can relative makes about the patient, hostility is
"opt out" of a remark which is critical only rated using a three-point scale. Although
in content if he or she implies that imper- initially incorporated into early definitions
fections in himlherself are in some way re- of EE (Brown, Birley, and Wing, 1972),
sponsible for the reaction shown, e.g., "It hostility ratings are now no longer used in
really annoys me when she does that but this way - principally because of the strong
Introduction to EE Measurement and Research 27
association between hostility and criticism tionship may be important in helping us un-
and the lack of predictive power of the hos- derstand why some patients do not relapse,
tility ratings when used alone. even when living within high EE families.
Like criticism, warmth is rated by focus-
ing on tonal change in the speaker. In this
Emotional Overinvolvement: case, however, the voice tone has to be
Emotional overinvolvement reflects a dra- clearly positive. Positive remarks, on the
matic or exaggerated emotional response to other hand, are defined primarily by con-
the patient's illness (e.g., "I said what hos- tent and reflect unambiguous praise or ap-
pital? Just imagine how I felt! I thought I'd preciation for some characteristic or behav-
have to go there myself from the shock.") or ior of the patient (e.g., "He's a wonderful
behavior which is excessively overprotec- husband."). Although the rating for posi-
tive ("I quit my job and went into debt so I tive remarks is based on the number of re-
can be home in case he ever needs me."). marks occurring during the interview,
Like hostility, emotional overinvolvement warmth is rated using a five - or six-point
is rated on a point scale, although typically scale.
this involves five or six points rather than Even though the principal component of
three. the EE rating (criticism) is rated primarily
The two final assessments, warmth and by focusing on what can often be quite sub-
positive remarks, have been given relatively tle tone changes in the voice of the relative,
little attention in the EE literature, probab- with adequate training it is possible for
ly in large part because empirically they highly reliable ratings to be made. EE train-
have been found to add little to the predic- ing typically takes about 3 weeks, and be-
tive power of EE ratings made using criti- fore a trainee is permitted to work inde-
cism and overinvolvement. However, they pendently, interrater agreement on criti-
are mentioned here for completeness and cism and emotional overinvolvement must
also because, at some future time, these be at least 0.80 (Pearson product-moment
positive aspects of the patient-relative rela- correlation) .
High EE = 57 patients
LowEE High EE
(13%) (51%)
~
< 35 hrs > 35 hrs
Subgroups
2 3
A 4 5
A 6
Psychophysiological Investigations
In an attempt to learn more about how high n = 30), no longer appears to do so. Stur-
EE effects might operate to influence re- geon, Turpin, Kuipers, Berkowitz, and
lapse rates in schizophrenic patients, re- Left's (1984) data now show no differential
search has, in recent years, turned to psy- effect of EE on the decline in electrodermal
chophysiological studies. These typically activity after the relative joins the patient
assess peripheral autonomic responses to and interviewer. Also, in contrast to Tarrier
high and low EE relatives, and recently et al., Sturgeon and his collegues report a
some interesting if conflictual data have mean rate of skin conductance in the high
emerged. EE patient group which is almost double
In a study carried out in 1979 in a group of that found in the low EE patients.
schizophrenic patients in remission, Tarrier, Since Sturgeon was using an acutely ill
Vaughn, Lader, and Leff were able to de- patient group, all of whom had high levels
monstrate that while both high and low EE of face-to-face contact with their relatives,
patient groups showed highly aroused phy- and since all his recordings were made while
siological response patterns during a IS-min the patient was in the hospital rather than at
period spent talking to a psychiatrist, short- home, there are a number of differences
ly after their relatives entered the room, the between the two studies which might ac-
rates of spontaneous fluctuations in skin count for the discrepant results. While it is
conductance in the patients with low EE re- difficult to understand the implications of
latives quickly habituated and approached the studies in the area of psychophysiology
normal levels. Patients with high EE rela- to date (many of the results seem to depend
tives on the other hand showed no such on the physiological index chosen and the
habituation upon entry of the relative. In- method of statistical analysis employed), it
stead, their arousal levels remained high does seem that patients do differ in their
throughout the full 30 min of recording. electrodermal activity according to the EE
While Sturgeon, Kuipers, Berkowitz, Tur- levels of their relatives. Whether these dif-
pin, and Leff (1981) later claimed to have ferences appear after the relative enters the
replicated Tarrier et al.'s earlier finding, a room or whether they are more long-stand-
recently published reanalysis of these initial ing is not yet clear however.
data, together with data subsequently col- Data from Valone, Goldstein, and Nor-
lected on an additional ten patients (total ton (1984) even suggest that mere antic-
30 J. M. Hooley
ipation of an interaction with a high EE rel- more chronic stress associated with high
ative can be arousing. Disturbed adoles- levels of contact with a high EE relative
cents who were waiting to interact with a seeming most crucial. Sturgeon et al. hy-
high EE parent showed higher levels of psy- pothesize that the rise in SCR frequency
chophysiological reactivity than adoles- which takes place in low EE patients during
cents who were anticipating interactions a psychiatric episode is a more transient
with a low EE parents. Moreover, within phenomenon than the rise which occurs in
direct interactions, high EE parents and high EE patients. They suggest this is be-
adolescents become significantly more phy- cause the former have been exposed to
siologically aroused than parents and off- more acute stress prior to the episode while
spring in the low EE group, although prior the latter group have endured life stress
to the interaction no differences in reactivi- which is more chronic. If electrodermal
ty level were evident in the parents. activity is thus in some way associated with
Valone et al.'s data provide good evi- vulnerability to relapse, this slow recovery
dence that encounters with high EE parents rate, argued to be characteristic of patients
are more emotionally arousing than compa- in the high EE group, would render such
rable interactions involving low EE family patients at increased risk of subsequent re-
members. Given this, an hypothesis pro- lapse until remission levels can be estab-
posed by Sturgeon and his co-workers is of lished.
some interest. One explanation these re- While the above is an attractive formula-
searchers offer for their finding that SCR tion and provides an alluring link between
frequencies differ between the high and low several areas of EE research, it must be
EE patient groups concerns a factor which stressed that at the present time the issue of
often precipitates relapse or onset in the the relation between electrodermal activity
two groups. As has been mentioned earlier, and vulnerability to schizophrenia cannot
within the low EE group, a schizophrenic be resolved. Clearly, however, psychophy-
episode is most frequently preceded by the siological studies have a valuable role to
acute stress of an independent life event play in EE research and are likely to pro-
(Leff and Vaughn, 1980). In the high EE vide some important insights into the
patient group, however, life events seem to dynamics of the concept in future years.
play a less important role in relapse, the
EE and Depression
So far in this chapter, only research carried between EE and relapse might not be a phe-
out in schizophrenic patients or individuals nomenon uniquely associated with schizo-
considered to be at risk for schizophrenia phrenic samples.
spectrum disorders has been considered. Since the cutoff of two critical comments
While this is only appropriate, given that utilized by Vaughn and Leff was deter-
schizophrenia has been central to almost all mined post hoc, a replication of the study
the research involving EE, some mention was clearly needed before more generality
should perhaps at this point be given to two for the EE construct could be claimed. The
studies which have examined the relation first full replication and extension of
between EE and relapse rates in depressed Vaughn and Leff's 1976 study has recently
populations. been completed by the author (see Hooley,
Vaughn and Leffs study of 1976 was the Orley, and Teasdale, in press) in a sample of
first to suggest that depressed patients, like 39 patients admitted to psychiatric hospitals
schizophrenics, might be vulnerable to the suffering from an episode of major depres-
influences of high EE relatives. Using a sive disorder. All patients involved in the
group of 30 depressed hospital inpatients, study were married, and consequently all
whose symptom pattern involved no delu- key relatives interviewed were spouses.
sions or hallucinations, Vaughn and Leff While no demographic or illness-related
were able to show that while the thresholds variables, such as number of symptoms,
of six or seven critical remarks which had severity of depression, or duration of the
been so useful in schizophrenic populations key depressive episode, were significantly
did not reveal any significant associations associated with 9-month relapse rates, a
with relapse when used on data from the de- significant relation between spouses' EE
pressed sample, decreasing the cutoff to levels and probability of relapse was evi-
two critical remarks did produce significant dent. Although 59% (14120) of patients liv-
effects. Specifically, when this lowered ing with spouses rated as high EE (two or
threshold was used to assign relatives as more critical comments made during CFI)
high or low EE, 67% (141:21) of patients liv- relapsed during follow-up, none (0/5) of the
ing with high EE relatives relapsed over the patients living with low EE spouses did so.
9-month follow-up period. In contrast, only These results thus provide confirmation of
22 % (2/7) of patients living with low EE re- Vaughn and Leff's original findings and
latives did so. These results were thus inter- suggest that the EE construct not only has
esting since they were the first to suggest predictive validity with respect to schizo-
that the previously well-established relation phrenic patients, but is also a potentially
Introduction to EE Measurement and Research 33
valuable predictor of relapse in depressed depressed patients, this is clearly an impor-
populations. While no intervention studies tant next step.
involving EE have yet been conducted with
Concluding Remarks
Despite the strength of the association be- related issues focus attention quite rightly
tween EE and relapse, we still know rela- on techniques of intervention - techniques
tively little about the mechanism by which to reduce high EE levels - we should also
EE might operate to bring about a return of consider that high EE in relatives may not
symptoms in psychiatric patients. Although invariably be a bad thing. Perhaps, as a con-
we now know more about the correlates of sequence of the attitude they adopt and
high and low expressed emotion attitudes, the behavior they show, high EE relatives
we still need to know much more about how promote higher levels of patient function-
EE can operate to affect patients when they ing than low EE relatives. True, patients
return home. High EE relatives seem in may relapse more often, but they may also
some way to constitute a form of increased achieve higher levels of intermorbid adjust-
social stress for vulnerable individuals. Al- ment which might, in turn, increase their
ternately, low EE relatives can be construc- overall psychosocial stress levels and conse-
ted as individuals capable of lowering stress quently their relapse risk. Thus, while inter-
levels in vulnerable patients. Regardless of vention studies such as that of Leff et al.
which perspective is taken, the psychiatric have demonstrated that high EE relatives
patient is seen as an individual who, for can learn much from exposure to the coping
whatever reason, seems excessively sensi- styles of low EE relatives, some of the po-
tive to the effects of social stress. tentially beneficial aspects of the high EE
While it is important to know what fac- attitude might also be valuably conveyed to
tors contribute to this sensitivity in patients, low EE relatives. Many challenging ave-
it is also important for us to learn more nues of research still await researchers in
about the development of EE in relatives. the field, and may important and fundamen-
What makes a relative high in EE? Is it a tal questions still remain to be answered.
trait? Are certain individuals born high in The next few years will be an important
EE or does it arise as a consequence of ex- time for EE research. Our understanding of
posure to a psychiatrically ill patient? If so, the dynamics of this valuable construct is
what kinds of patients and in response to only just beginning.
what kinds of symptoms? While practically
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chiatry, 141, 121-134. orders. Journal of Abnormal Psychology, 93,
Leff, J., and Vaughn, C. (1980). The interaction 448-457.
of life events and relatives' expressed emotion Vaughn, C. E. (1977). Patterns of interaction in
in schizophrenia and depressive neurosis. Brit- families of schizophrenics. In H. Katschnig
ish Journal of Psychiatry, 136, 146-153. (Ed.). Schizophrenia: The other side. Vienna:
Miklowitz, D. J., Goldstein, M. J., and Falloon, Urban and Schwarzenberg.
I. R. H. (1983). Premorbid and symptomatic Vaughn, C. E., and Leff, J. P. (1976). The in-
characteristics of schizophrenics from families fluence of family and social factors on the
with high and low levels of expressed emotion. course of psychiatric illness. British Journal of
Journal of Abnormal Psychology, 92 (3), Psychiatry, 129, 125 - 137.
359-367. Vaughn, C. E., andLeff, J. P. (1981). Patterns of
Rutter, M., and Brown, G. W. (1966). The re- emotional response in relatives of schizophre-
liability and validity of measures of family life nic patients. Schizophrenia Bulletin, 7 (1),
and relationships in families containing a psy- 43-44.
chiatric patient. Social Psychiatry, 1,38-53. Vaughn, C. E., Snyder,K., Freeman, W.,Jones,
Sturgeon, D., Kuipers, L., Berkowitz, R., Tur- S., Falloon, I., and Liberman, R. (1982). Fami-
pin, G., and Leff, J. (1981). Psychophysiologi- ly factors in schizophrenic relapse: A replica-
cal responses of schizophrenic patients to high tion. Schizophrenia Bulletin, 8 (2), 425-426.
and low expressed emotion relatives. British Vaughn, C. E., Snyder, K. S., Jones, S., Free-
Journal of Psychiatry, 138,40-45. man, W. B., and Falloon, I. R. H. (1984).
Sturgeon, D., Turpin, G., Kuipers, L., Berko- Family factory in schizophrenic relapse. Archi-
witz, R., and Leff, J. (1984). Psychophysiologi- ves of General Psychiatry, 41,1169-1177.
cal responses of schizophrenic patients to high Wing, J. K., Cooper, J. E., and Sartorius, N.
and low expressed emotion relatives: A follow- (1974). The description of psychiatric symp-
up study. British Journal of Psychiatry, 145, toms: An introduction manual for the PSE and
62-69. catego system. London: Cambridge University
Tarrier, N., Vaughn, c., Lader, M. H., and Leff, Press.
3. Expressed Emotion in Cross-Cultural Context:
Familial Responses to Schizophrenic Illness
Among Mexican Americans*
J. H. Jenkins, M. Karno, A. de la Selva, and F. Santana
Methodology
with a history which suggested that the pri-
Patients
mary disorder was affective, organic, or
Patients recruited to the COSAMA project drug- or alcohol-related were excluded
have met the following criteria: from the study, as were those who did not
1. Diagnosed schizophrenic by the Present return to live in the household in which they
State Examination (PSE) and DSM-III were living prior to the index admission. At
criteria the time of the PSE, the Brief Psychiatric
2. Of bilateral Mexican descent Rating Scale (Overall and Gorham, 1962)
3. Between 18 and 50 years of age was also completed. Once the patient had
4. Living with parent, spouse, or other been diagnosed as schizophrenic, home
close relative for at least 1 of the 3 visits were scheduled with the patient's fam-
months prior to hospital admission ily.
The patients were recruited exclusively
from public mental health services in the
Assessment of Relatives
counties of Los Angeles and Ventura. With
the exception of ethnicity, the inclusion cri- Within several days after the patient's ini-
teria employed in the Anglo-American stu- tial diagnosis, adult key relatives - those
dies ofEE were similar to those of the Mexi- with whom the patient had an ongoing rela-
can-American project. tionship within the residential household -
were administered the Camberwell Family
Assessment of Patients Interview (CFI), which has been described
in detail by Vaughn and Leff (1976b).
Screening
The CFI is a partially structured inquiry
All patients were initially interviewed by a into the experience of the patient's illness
fieldworker fluent in Spanish, who estab- and its influence upon the life of the family
lished rapport, determined whether the di- during the 3 months prior to index hospitali-
agnosis was likely to be one of schizophre- zation. The CFI typically yields lenghtly
nia, and established that the patient met all and detailed narrations of family events and
other inclusion criteria, and who then ob- the emotional atmosphere of the house-
tained informed consent. hold. The abbreviated version of the CFI
takes about 1.5- 2 hs to complete and is au-
Diagnosis diotape-recorded for later scoring. In par-
ticular, the interviewer probes for and ob-
All patients were interviewed as soon as serves the expression of emotions and atti-
possible after admission - in accord with tudes expressed by family members toward
their capacity to consent and participate - the patient. The initial CFI interviewers of
by a bilingual clinical psychologist who had the COSAMA project (de la Selva and Jen-
been trained to research reliability in the kins) were trained in a 2-week workshop led
PSE. The ninth edition of the PSE was used by Vaughn and Snyder~ followed by several
in its official IPSS Spanish version. Patients months of training in the rating of Anglo-
1 The UCLA Mental Health Clinical Research
Center for the Study of Schizophrenia, MH- 2In the winter of 1980, Christine Vaughn, Ph.D.,
30911, R. P. Liberman, M.D., Principal Investi- and Karen Snyder, M. A., conducted a training
gator. All three research projects reported upon workshop in the administration of the Camber-
here for the Mexican-American and Anglo-Ame- well Family Interview and ratings of expressed
rican data were supported by the UCLA- emotion at Camarillo State Hospital, Camarillo,
MHCRC. California.
Expressed Emotion in Cross-Cultural Context 39
American and British "master" audiotapes three component ratings of EE, viz., the
of the various CFI scales. Both achieved number of critical comments, hostility, and
high interrater reliability scores with the emotional overinvolvement.
original ratings (above Pearson r of 0.90).
Periodic reliability checks were completed
Additional Procedures
within the project to ensure the ongoing re-
liability of the ratings. While the focus of this report is on data col-
lected within the CFI, data from several ad-
ditional procedures were also employed.
Translation and Development
These materials are important for the inter-
of the Spanish eFI
pretation of EE within the Mexican-Ameri-
Two independent Spanish translations of can family context. They include interview
the CFI were made, one by a professional schedules which inquire into following
native Spanish-speaking translator and lan- areas: social-psychiatric histories of the pa-
guage teacher, the other by de la Selva. The tient; sociodemographic data related to the
two translations were integrated into a composition of the household; social net-
single first draft translation, which was then works of the patient; level of acculturation
back-translated into English by Santana of key relatives and patients; and family
(who was "blind" to the CPI in English). members' ethnopsychiatric understandings
The integrated first translation was re- of the nature of schizophrenia and patterns
viewed line-by-line in comparison with the of coping with the problem. Also, ethno-
back-translation and original English ver- graphic observations of the household,
sion to resolve discrepancies and to produce neighborhood, and community were ob-
a semifinal translation that was utilized in tained.
22 pilot interviews with Spanish-speaking Since the primary goal of the project was
relatives of schizophrenic Mexican-Ameri- to assess the relationship of schizophrenic
cans in Ventura and Los Angeles Counties. outcome to family EE profiles, the clinical
These tape-recorded interview experiences status of the patient was regularly monitor-
were than reviewed to produce a final trans- ed. The follow-up phase of clinical status
lation of the CPI, which was revised and has yet to be completed and therefore will
adapted for local, colloquial Mexican- not be reported upon here. The purpose of
American usage. this initial report is the exploration of the
All CFI interviews were scored for vari- nature and meaning of EE among Mexican-
ous scales described by Vaughn and Leff American families coping with schizophre-
(1976b), but the major focus was on the nic illness.
Sample Characteristics
Selected sociodemographic and clinical scale developed by Cuellar, Harris, and J as-
characteristics of the Mexican-American so (1980), both the key relatives and pa-
patients, along with those of the matched tients tended to be relatively unacculturat-
Anglo-American comparison group, are ed. Most (65%) of the key relatives (often
presented in Table 1. The samples are simi- parents) were predominantly or only Span-
lar in many respects. Nearly all of the fami- ish-speaking, while only 43.4% of patients
lies were of lower socioeconomic status ac- were similarly monolingual. The vast ma-
cording to Hollingshead's (1957) index of jority (90%) of the sample were Catholic.
social position. The mean size of household was signifi-
The majority (79%) of the Mexican- cantly different among the Mexican-Ameri-
American key relatives were first-genera- can families compared to that of the Anglo-
tion Mexicanos, i.e., born in Mexico. A American sample, 6.7 and 3.6 persons, re-
similar percentage (73%) of the Mexican- spectively (P < 0.001). Further, Mexican-
American patients were first-generation American households of the present sam-
immigrants. According to the acculturation ple are characterized by large networks of
40 J. H. Jenkins et al.
Table 1. Selected Sociodemographic and Clinical Features of the Mexican-American (MA) and
Anglo-American (AA) Patient Samplesa
Variable MA AA
n % n %
Patients 30 100.00 30 100.00
Sex
Females 11 36.7 11 36.7
Males 19 63.3 19 63.3
Mean age 27.4 25.2
Marital status
Never married 22 73.3 26 86.7
Married 4 13.3 0 0.0
Separated, divorced, widowed 4 13.3 4 13.3
Length of illness
(mean number years) 5.5 4.3
Number of hospitalizations
(mean) 3.1 3.4
Family type
Parental 22 73.3 28 93.3
Sibling 3 10.0 1 3.3
Marital 3 10.0 0 0.0
Other 2 6.7 1 3.3
Socioeconomic status
(Hollingshead two-factor index)
III 1 3.3 2 6.7
IV 14 46.7 13 43.3
V 15 50.0 15 50.0
locally residing kin who frequently visit the mic support for the families.
household, providing emotional and econo-
EE in Cross-Cultural Context
The importance of the EE construct has lated to familial response to schizophrenia,
been demonstrated for British and Anglo- factors underlying various patterns of EE
American psychiatric patients and their that are culturally distinctive as well as
families; however, its relevance and mean- more universal in nature need to be identi-
ing in other cultural contexts among non- fied. Discovery of features associated with
English speakers must be established if the EE profiles will contribute to the develop-
EE concept is to gain a wider cross-cultural ment of theoretical models informative of
validity. Variation in levels and types ofEE ways in which sociocultural processes may
needs to be explored. Moreover, since EE serve to influence the course of schizophre-
is an index which taps a host of features re- nic illness.
Expressed Emotion in Cross-Cultural Context 41
Cross-Cultural Variability ofEE
Vaughn et al. (1984) reported a signifi- The percentages of EE presented in
cant difference between the EE profiles of Table 2 reveal that EE was rated highest
British and Anglo-American families of among Anglo-American families and low-
schizophrenic patients. Slightly over one- est among Mexican-Americans. While this
half of the British households were low in may seem suggestive of cultural differences
EE (Brown, Birley, and Wing, 1972; in EE, it is necessary to take into considera-
Vaughn and Leff, 1976a) as against only tion other features that could account for
one-third of Anglo-American families. this variation. One such major concern is
While this report is based on comprehen- that of socioeconomic status. Leff (1977,
sive analyses completed for the first 30 fam- p. 321) has highlighted "the importance of
ilies included in the Mexican-American matching for social class in studies of emo-
study, the EE scores for the entire sample tional expression."
(n = 70) will be briefly presented here. To investigate styles of EE that may be
These data, together with those collected related to features that are cultural in na-
for the British and Anglo-American sam- ture, Jenkins (1984) compared the EE pro-
ples, establish the significant variation in files of lower socioeconomic status families.
patterns of EE across sociocultural settings Thirty Mexican-American and 30 Anglo-
and are presented in Table 2. A household American families (Table 1) living in South-
is defined as being high in EE if one or more ern California were studied. The Mexican-
key relative was rated as high in EE. American families were the first 30 recruit-
The above percentage of high vs low EE ed to the COSAMA project described
were made using the original cutoff points above, and the Anglo-American families
(Six or more criticisms and/or a score of were selected from the project reported on
4-5 on the EO! scale) as designated by the by Vaughn et al. (1984) and an ongoing
British researchers. These have been em- UCLA-MHCRC project.3
ployed here for purposes of cross-cultural The results of overall household EE for
comparison. However, it should be noted these matched subsamples are presented in
that upon completion of data collection for Table 3. A striking difference between
all clinical assessments, a different baseline these two ethnic groups was found: Anglo-
could later prove important for the predic- American schizophrenic patients were con-
tion of schizophrenic relapse among Mexi-
can-American families. 3 See Footnote at bottom of p. 38.
a Note. From "Family Factors in Schizophrenic Relapse: A California Replication of the British Re-
search on Expressed Emotion" by C. E. Vaughn, K. S. Snyder, S. Jones, W. B. Freeman, and I. R.
H. Falloon, 1984, Archives of General Psychiatry, 41, pp. 1169-1177.
b Note. From "Influence of Family Life on the Course of Schizophrenic Disorders: A Replication" by
G. W. Brown, L. T. Birley, andJ. K. Wing, 1972, British Journal of Psychiatry, 121, pp. 241-258 and
Vaughn, C., and Leff, J. (1976). The influence of family and social factors on the course of psychiatric
illness: A comparison of schizophrenic and depressed neurotic patients. British Journal of Psychiatry,
129,125-137.
Overall x 2 = 9.90, d.f 2, P < 0.02; Anglo-American-British, Yates corrected x 2 = 5.84, d.f 1, P <
0.02; Mexican-American-British, Yates correctedx2 = 0.530, NS; Anglo-American-Mexican-Ameri-
can, Yates correctedx2 = 7.92, d.f 1, P < 0.01.
42 J. H. Jenkins et al.
Table 3. Comparison of Overall EE Profiles for Mexican-American and Anglo-American Households
of Lower Socioeconomic Status
Mexican-American Anglo-American
(n = 30) (n = 30)
LowEE 17 56.3 5 16.7
HigbEE 13 43.3 25 83.3
Note. From "Schizophrenia and the Family: Expressed Emotion Among Mexican-Americans and
Anglo-Americans" by J. Jenkins, 1984, University of California, Los Angeles.
siderably more likely to reside in high EE tionship of key relatives (mother, father,
home environments than were their Mexi- sister, and so forth), type of household (pa-
can-American counterparts. rental, marital, sibling), or variation among
It should be noted that the EE percent- the lower levels of socioeconomic status
ages reported upon here for the lower socio- [Hollingshead (1957) levels IV or V] also
economic status Anglo-American compari- proved unrelated to EE profiles. Rather,
son group are typical for the entire subsam- the highly significant difference is account-
pIe of such cases within the study completed ed for by the ethnic identity of the family
by Vaughn et al. (1984). (Mexican-American or Anglo-American).
Thus, it appears that differences in EE This is compelling evidence for major dif-
profiles are related not only to ethnicity but ferences in cultural styles of emotional re-
also to the socioeconomic status of key rela- sponse to schizophrenic illness within the
tives. The higher percentage ofEE (83.3%) family. We turn now to a discussion of some
found here, compared with that of the en- qualitative aspects of these styles and an ex-
tire Anglo-American sample (67%) of 69 ploration of some of the features that seem
families, is due to the selection of cases of to characterize patterns of EE among Mexi-
lower socioeconomic status. Analysis of can-Americans. Materials analyzed for the
variance and covariance revealed that ob- comparably matched Anglo-American
served differences in the EE profiles were sample will be employed to highlight cultur-
not significantly related to patient charac- al contrasts. In light of the finding that eth-
teristics (sex, age, marital status, edul::a- nicity and social class figure prominently in
tion, employment status, number of hospi- styles of emotional expression, it is evident
talizations, length of illness, socially disrup- that a greater appreciation of sociocultural
tive symptomatology, or level of premorbid factors is needed.
adjustment). Furthermore, the type ofrela-
Sociocultural Nature of EE
A first step toward an understanding of the Every cultural system includes patterned ideas
variation in EE among different ethnic regarding certain interpersonal relationships and
groups is appreciation of the fact that EE is certain affective states, which represent a selec-
inherently sociocultural and qualitative in tion from the entire potential range of interper-
nature. This is not to suggest that EE is not sonal and emotional experiences. The child, gro-
wing up within the culture and gradually inter-
amenable to quantitative analysis, but rat- nalizing these premises, undergoes a process of
her to underscore the point that EE indexes socially guided emotional specialization. He
a wide array of behaviors, emotions, and at- learns, in a sense, a special vocabulary of emo-
titudes which are part of an individual's cul- tion.
tural repertoire, developed through proces-
ses of socialization. As noted by Geertz Explantations of cross-cultural differences
(1959, p. 225): in the expression of emotion must include
Expressed Emotion in Cross-Cultural Context 43
an understanding of the "vocabulary of Anglo-American relatives reported feeling
emotion" characteristically employed by sad (particularly those relatives rated low in
individuals. EE), this did not occur as frequently as
among Mexican-American family mem-
bers. Feelings of sadness (tristeza), sorrow
Low EE Profiles Among
(pena), and pity (ltistima) were commonly
Mexican-Americans
voiced. This was especially true of Mexican-
The majority (69%) of Mexican-American American women. Verbalizations of sad-
key relatives were rated low in EE. This fig- ness were often accompanied by evidence
ure varies remarkably from that for the of warmth and sympathy for the patient and
Anglo-American key relatives of the mat- his or her condition.
ched comparison group, as shown in Such expressions of sadness or sorrow
Table 4. over the illness of a close family member
These percentages provide a more indi- may reflect genuine feelings on the part of
vidualized view of EE than does the overall the relative. On the other hand, they should
household index used for predicting re- also be regarded as culturally appropriate
lapse. Clearly, most of the Mexican-Ameri- responses to schizophrenic illness within
can family members tended not to be highly the family. As Nichter (1981) has recently
critical, overinvolved, or hostile toward pointed out, every culture provides its
their ill relatives. While this may indicate members with a variety of ways to express
the absence of certain kinds of verbally ex- emotions, including distress. Faced with
pressed emotions or communications with- what they may view as a serious illness or
in the family, it tells us relatively little about condition - whether temporary or long-
what other sorts of patterns might be ac- term - Mexican-American relatives ex-
tively shaping the household environment. press feelings that acknowledge an inher-
Moreover, the EE percentages do not say ently distressing situation, and the Spanish
anything about whether low EE among language provides a rich lexicon of emotion-
Mexican-Americans is similar in kind to low al terms to express feelings of unhappiness
EE profiles among other cultural groups. or distress. While some low EE relatives ex-
We will now turn our attention to a discus- pressed emotions related to their ill relative
sion of some of the contours and major that included anger or resentment, expres-
components of these low EE Mexican- sions of sadness clearly predominated over
American relatives. those of indignation or antipathy. How-
One of the most striking findings was that ever, several relatives reported that they at-
feelings of sadness as conveyed through the tempted to keep their feelings of sadness to
content and tone of the relatives' verbal be- themselves, fearing that the patient might
havior would often pervade the interviews. be adversely affected by their feelings of
This contrasted sharply with emotional re- being distraught.
sponses characterized by anger, indigna- Low EE profiles of Mexican-Americans
tion, and frustration that were frequently are also linked to ethnopsychiatric views of
displayed by high EE relatives. While the the nature of the problem that has beset
Mexican-American Anglo-American
(n = 49) (n=47)
LowEE 34 69.4 18 38.3
HighEE 15 30.6 29 61.7
Note. From "Schizophrenia and the Family: Expressed Emotion Among Mexican-Americans and
Anglo-Americans" by J. Jenkins, 1984, University of California, Los Angeles.
44 J. H. Jenkins et al.
their ill relative. These ethnopsychiatric or sponses to symptom behaviors. A content
"folk" models for interpreting schizophren- analysis of critical comments by Jenkins
ic behavior are complex and merit in- (1984) revealed that Mexican-American
depth treatment that would be beyond the key relatives were far less likely to criticize
scope of this chapter. However, we will at- symptom behaviors than were their Anglo-
tempt to briefly summarize some of the American counterparts. These data provide
more salient aspects of these models and support for the proposition current in the
their relationship to low EE. Of principal literature that Hispanics tend to be relative-
significance is that Mexican-Americans do ly tolerant of psychotic symptomatology
tend to view the problem as one of illness; it (Fabrega, Swartz, and Wallace, 1968; Rog-
would appear that psychosis is commonly Ier and Hollingshead, 1965; World Health
considered to be an illness-related problem Organization, 1979). The Mexican-Ameri-
cross-culturally (Murphy, 1982). Among can relatives demonstrated a great deal of
Mexican-Americans, the problem is often tolerance, patience, and respect toward the
considered to be associated with one's "ner- schizophrenic family member and would
ves" or mental condition. In whatever man- seldom challenge or take exception to psy-
ner the illness may be conceptualized, it is chotic behaviors. Many relatives reported
typically believed to be legitimate. Fre- that confrontations with a sick family mem-
quently, the relatives would refer to the "ill- ber were unwise and did little to change
ness" independent of any prompting from matters.
the interviewer and in advance of any que- Low EE Mexican-American families
ries by the interviewer into the relative's would sometimes interpret symptom behav-
view of the nature of the problem. Most in- iors in a sympathetic or favorable light. For
formants were firm in their conviction that example, one young woman spent a great
the patient suffered from an illness prior to deal of time sitting alone and laughing to
the time that he or she was first hospitalized herself for no apparent reason. Her moth-
for the present troubles. er's view of this behavior was not a critical
Belief in the legitimacy of schizophrenia one; rather, she reported feeling glad that
as an illness is also linked to views that sym- her daughter was able to find some momen-
ptom-related behaviors generally lie out- tary relief from the very difficult circum-
side the patient's control. Some of the fol- stances of her life by simply being able to
lowing comments4 made during the course laugh at her troubles. In another instance, a
of the interviews illustrate this point: mother viewed her son's habit of sleeping
If he doesn't want to do anything it's because he's until early afternoon as potentially benefi-
sick; he always worked hard in school and jobs cial and clearly understandable, given that
before. He must be sick. he was typically up quite late into the night,
I knew right away that this wasn't Luis. I know unable to sleep because he was continually
what he was doing wasn't his fault. bothered by voices. She believed that sleep
She would like to get well ... if she could. was crucial to his recovery and that he
These comments are similar to those made should sleep whenever he was so inclined or
by low EE Anglo-American relatives: able. With respect to this same behavior -
If he could really control himself, I think that he sleeping late - another key relative's re-
would. sponse to his wife's routine of sleeping until
She's always looking for help. She tries the best to noon every day was to say, "Let her sleep as
help herself to get healthy. She tries her best- late as she likes! She is my queen!" These
looking for doctors to help her ... I don't think examples should not be taken as evidence
she could do any more. She's a fighter. She wants that Mexican-Americans do not recognize
to be well. these sorts of behavior as indicative of men-
Ethnopsychiatric views of the nature of the tal illness, for as discussed above, they do.
problem also influenced the relatives' re- Rather, these vignettes should be viewed as
exemplary of relatives' efforts to interpret
4 The qualitative materials reproduced here are such behaviors in a noncritical manner.
verbatim quotations from CFI materials and orig- Finally, low EE profiles among Mexican-
inally appeared in Jenkins (1984). Americans are linked to strong notions of
Expressed Emotion in Cross-Cultural Context 45
the importance of family bonds, which are ments or confrontations, and (4) large kin-
enduring and unchanging. The strength of based households and networks in which a
family ties demonstrated in the face of long- sense of the importance of family bonds
term schizophrenic illness is often remarka- induces relatives to assume responsibility
ble, although the type of relationship (par- for the patient's care and recovery.
ent, spouse, and so on) is often influential.
Mothers tend to be the most devoted, fol-
lowed by fathers, sisters and brothers, and High EE ProfIles Among
spouses. This may be common across a vari- Mexican-Americans
ety of cultural contexts. Much of the Mexi-
can-American relatives' compassion stem- The above positive features of low EE
med from a deeply felt commitment to a households are not universally found
family member, particularly one who is seri- among Mexican-American families. In con-
ously ill. Many relatives reported that they trast to the low EE Mexican-American rela-
felt a great deal more affection for the pa- tives for whom sadness seemed to represent
tient as a result of the illness. Several made a major emotional orientation toward the
passionate statements about how they illness, high EE respondents were likely to
would never, indeed could never, leave express feelings of anger and indignation.
their ill relatives to fend for themselves "in In fact, one of the most common ways a
the streets." high EE Mexican-American relative would
Another feature that we believe is related express criticism would be to comment on a
to the predominance of low EE profiles behavior by saying mi di6 mucho coraje (it
among Mexican-Americans is the size and made me very angry). These relatives were
structure of the families. As was discussed often distressed over behaviors they viewed
earlier in connection with the sample charac- as unacceptable. For example, the father of
teristics, Mexican-American nuclear house- one female patient made seven critical com-
holds tended to be larger than those of the ments during the course of the interview,
Anglo-Americans. In nearly all ofthe Mexi- and within four of these criticisms he made
can-American households, locally residing reference to the anger that certain behav-
kin visit the home frequently, providing iors would provoke in him. These criticisms
emotional and instrumental support and as- centered on the patient's tendency to argue,
sistance. This includes help in alleviating insult and swear at family members, and
the stress generated by living with schizo- throw objects about the house.
phrenic illness. In some families, caretaking Moreover, some high EE relatives, un-
of the ill relative was shared among various like those in low EE families, more often
relatives, thereby allocating the burden of doubted whether their family member was
responsibility among several individuals. truly ill. These relatives would point out
Large family size may also inhibit the devel- that the patient's symptoms would some-
opment of patterns of overinvolvement or times wax and wane. More frequent, how-
critical attitudes and behaviors. For exam- ever, were doubts that their relative could
ple, occasionally, key relatives would ex- possibly be mentally ill. This may indicate
press regret over not having more time to that high EE relatives had a greater tend-
devote to their ill relative, since responsibili- ency to deny the problem of mental illness
ties to other family members tended to de- in their family or to experience greater feel-
tract from their efforts in this regard. ings of shame and stigma associated with it.
To summarize, low EE among Mexican- Thus, one Mexican-American father be-
Americans is patterned along four dimen- lieved that his son might not be truly ill since
sions: (1) sadness as a predominant emo- he sometimes seemed ill and other times
tional response to the problem, (2) ethno- not; in any case, he claimed that it had gone
psychiatric models of schizophrenia that on long enough.
view the problem as a serious, legitimate ill- Among the high EE Anglo-American
ness outside of the patient's locus of con- relatives, often there was doubt or disbelief
trol, (3) styles of coping with troublesome in the legitimacy of the illness. These rela-
behaviors in a manner which avoids argu- tives would express the view that even if
46 J. H. Jenkins et al.
their relative was in fact ill, he or she could ly expressed. For example, Mexican-Amer-
surely exercise powers of personal initiative icans stated flatly that it was important that
and control in determining the course of the their relatives work or be active for their
illness, should they be so inclined. own sakes or in order that they be able to
A lot oftimes it wouldn't have happened if she ... take care of some of their own personal
saw it coming ... to me I think she could have needs.
done something about it and you know with me I He has to dress, to have money, work, so he can
can talk with someone and try to help them, but go out, have a girlfriend, because we can't give it
if they don't help themselves and don't give a all to him.
damn ... that's where it bugs me ... She wouldn't Look, my son, it's not good for someone to sleep
do anything - like she wanted to feel sorry for till 2:00 in the afternoon! We have to go to work,
herself ... She was just giving up ... I don't like to do something! (see Footnote 4).
see that. I don't like to see someone give up when
there's still something to fight for ... I say, "Why Anglo-American relatives, on the other
aren't you trying, don't give up," because to me hand, displayed critical attitudes toward in-
people who do that I can't get along with ... I activity or unemployment, frequently in-
can't get along with someone who sees the prob- ferring negative assessments of their rela-
lem and does nothing, just lets it happen ... and tive's character or personality:
I start to get a dislike.
I don't know if she has a button she can push or . .. he just didn't have no ambition to do anything
what ... that girl can fool you and fool anybody ... 20 years old, right in his prime ... but now he
... She can go like that and be as normal as you or should be involved but he's not. He would just sit
there in the chair and watch TV all the time.
I (see Footnote 4).
No ambition - doesn't care for nothing ... I
There were few differences between high should say doesn't care for anything, class up my
and low EE Mexican-American relatives English. The way I said it was to emphasize that
with respect to criticism of symptom behav- worthlessness of his. Useless.
She's too darn lazy. That's her trouble.
iors. Although generally speaking, high EE Do this today and you want to do this tomorrow,
relatives were more likely to be critical of or you never will make it. You've gotta make up
the patient, there was not a disproportion- your mind and go after it (see Footnote 4).
ate amount of attention focused on symp-
tom behaviors per se. This differed greatly Styles of coping and adaptation to schizo-
from comments made by high EE Anglo- phrenic illness among high EE Mexican-
Americans. They expressed discomfort Americans were typically different from the
concerning psychotic behaviors, as the fol- strategies employed by low EE relatives.
lowing remarks about conversation illus- High EE relatives would attempt to change
trate: undesirable behaviors through scolding,
... bugged the hell out of me, the thing that really admonitions, explanations, and avoidance.
drove me up a wall was her starting a conversa- In contrast to low EE coping styles, these
tion and not finishing it. I mean it really bugged responses were reactive and combative.
me.
She'd talk, talk, talk, talk, talk, about God or
Furthermore, some relatives tended to be
whatever - religion - you can't correct her and intrusive in ways that were uncharacteristic
I would not correct her ... but that constant of low EE relatives. For example, some rel-
drone is enough to drive me up a wall. atives would search through the patient's
I can't even remember some of the horrible personal things or listen in on telephone
things he'd come out and talk about ... and actu- conversations to gamer information con-
ally he was making me nervous. The things that cerning their activities.
he'd talk about (see Footnote 4). These kinds of responses were common
Cultural· differences between Mexican- to high EE Anglo-Americans relatives, as
Americans and Anglo-Americans were also well. These high EE relatives, however,
apparent in criticisms directed toward in- were more likely to report frequent "nagg-
activity or unemployment on the part of ing" of the patient, as the following exam-
schizophrenic relatives. While critical rela- ples demonstrate:
tives of both ethnic groups were likely to I am a nagger, well, normally [about] him doing
complain about these behaviors, they dif- things wrong. I am a nagger. I've tried to break
fered in the nature of criticisms they typical- myself of it, but I do nag him.
Expressed Emotion in Cross-Cultural Context 47
Sometimes I nag. I'm so exasperated ... mostly band since divorce was not possible within
about money [she throws away] and the fact that the Catholic church. This she accepted, al-
she always sits around ... (see Footnote 4). though in one instance she reported that her
Despite the critical attitude displayed by husband's incessant complaints concerning
high EE relatives, this did not alter their the living conditions of the household drove
sense of familial commitment toward their her to exclaim, "Look, if you're not happy
ill relative. In this regard, they did not here, there is the door! I've had it! I'm 'up
markedly differ from low EE relatives. to here!" The fact that only one such in-
There was only one instance in which a key stance occurred lends strong support to the
relative demonstrated a rejecting attitude. prevailing views concerning Mexican-Ame-
This case was a martial household in which rican familism and to the view that Mexi-
the wife, very weary of her husband's con- can-American relatives display high levels
tinuously psychotic condition throughout of acceptance toward schizophrenic rela-
their 9 years of marriage, sought a divorce. tives in the home, even when high EE char-
Her priest, however, counseled against such acterizes the mode of response toward
a move and told her to remain with her hus- them.
Conclusion
Both quantitative and qualitative analyses by schizophrenic illness.
of EE among Mexican-American families Comparative data from a matched sam-
revealed a predominance of low EE styles ple of Anglo-American families demon-
of response to a schizophrenic family mem- strated significant variations in EE across
ber. These low EE profiles were found to be cultures. While Mexican-Americans tended
patterned along several dimensions, many to be typically low in EE, the converse was
of which were notably different from those true of Anglo-Americans, for whom high
characteristically employed by high EE rela- EE profiles dominated. Although some
tives. In general, low EE family members similarities across high and low EE styles for
provided their schizophrenic relatives with these two ethnic groups were noted, there
a great deal of tolerance, sympathy, and were several aspects of EE styles (both high
support. However, not all Mexican-Ameri- and low) that were culturally distinctive to
can individuals responded in this fashion. Mexican-Americans. While these patterns
High EE relatives displayed anger, impa- of response may not be unique to Mexican-
tience, and frustration related to the pa- Americans when viewed in broader cross-
tient's troublesome behaviors. The strength cultural perspective, they do suggest that
of family bonds and affection was typically the sociocultural context may be influential
in evidence for both high and low EE rela- in shaping an individual's response to a schi-
tives alike, despite the difficulties generated zophrenic family member.
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4. Do Relatives Express Expressed Emotion?*
A. M. Strachan, M. J. Goldstein, and D. J. Miklowitz
Introduction
Recent research has shown that family in- 15), the way in which emotional attitudes
tervention programs, in combination with are communicated and problems are solved
neuroleptic medication, can have dramat- may be crucial factors, with expressed emo-
ic effects on the course of schizophrenia in tion (EE) as a key index of such processes.
terms of both psychiatric and social func- This chapter focuses on the interactional
tioning (Goldstein, Rodnick, Evans, May, correlates of EE, a measure based on rat-
and Steinberg, 1978; this volume, Chaps. ings of an interview with a relative. Such
12-14). All these programs have focused ratings have been correlated in a number of
on treating and supporting the family as a studies with direct behavior between the
unit, although it has not always been clear patient and a relative, providing measures
what important aspects of family function- of the congruence and incongruence be-
ing these programs affect. However, as sug- tween behavior in these two situations.
gested by Goldstein and Strachan (Chap.
Table 2. Benign and Harsh Criticisms Expressed to Patients by Dual High, Mixed, and Dual Low EE
Parental Pairs
Significant differences (P < 0.05): benign criticism, c < b, c < a; harsh criticism, a> b, a > c
Note: From "Parental Expressed Emotion and Affective Style in an Adolescent Sample at Risk for
Schizophrenia Spectrum Disorders" by K. Valone, J. P. Norton, M. J. Goldstein, and J. A. Doane,
1983, Journal of Abnormal Psychology, 92, pp. 399-407.
54 A. M. Strachan et a1.
data from both dyads and triads were sum- show that the sharpest predictor of critical
med. When dyadic and triadic data were behaviors from EE attitudes occurred when
examined separately, it was found that high the EE profile of the parental pair was
EE mothers made more benign criticisms examined together, as would be predicted
than low EE mothers in the dyads, whereas by family-systems theorists.
there was no difference for fathers. There Unfortunately, in this study there was an
were trends for both mothers and fathers to almost complete absence of emotionally
use more benign criticisms in the triad. overinvolved parents so that it was not pos-
Next, the authors examined the synergist- sible to study the behavioral correlates of
ic influence of parents on each other's ex- such an attitude. This may have been be-
pression of criticism. They divided the fami- cause the sample was not one of schizophre-
lies into dual low EE (both parents low EE), nics but of problem adolescents who may
mixed EE (one parent high, the other low), elicit critical responses from parents but
and dual high EE (both high EE). They whose protective responses are in the nor-
found that the three parental EE profile mal range. The next two studies to be de-
groups differed significantly in the expres- scribed overcame these drawbacks by study-
sion of both benign and harsh criticism (see ing relatives of schizophrenics, some of
Table 2). More specifically, data analyses whom had emotionally overinvolved atti-
suggested that the high EE parent in mixed tudes.
EE parental pairs is especially prone to ex- Miklowitz, Goldstein, Falloon, and Doa-
press benign criticisms toward the adoles- ne (1984) assessed the relationship between
cent. However, the presence of the low EE EE attitudes and direct interactional be-
spouse in the mixed EE families appears to havior with a sample of schizophrenic pa-
inhibit the frequent expression of harsh criti- tients and their parents from 42 families. A
cism by the high EE parent. These data count was made of the total number of nega-
10
c-
en
Q)
E
8
Critical statements Intrusive statements
--
Q)
til 6
en
0
....
Q)
..c 4
E
:::J
C
c 2
co
Q)
~
0
LowEE High EE- High EE- High EE- Low EE High EE- High EE- High EE-
Critical Overinvolved Critical and Critical Overinvolved Critical and
EOI EOI
(n = 7) (n = 14) (n = 5) (n = 4) (n = 7) (n = 14) (n = 5) (n = 4)
10
-
en
c
(1)
8
--
E
(1)
6
-
co
en
0
....
(1)
4
.0
E
::l
C
2
c
co
(1)
~
0
Low EE High EE- High EE- High EE- Low EE High EE- High EE- High EE-
Critical Overinvolved Critical and Critical Overinvolved Critical and
EOI EOI
(n = 28) (n = 11) (n = 16) (n = 7) (n = 28) (n = 11) (n = 16) (n = 7)
Fig. 2. Mean number of critical and intrusive statements in direct interaction among high and low EE
parental subgroups
Note. From "Emotional Attitudes and Direct Communication in the Families of Schizophrenics: A
Cross-National Replication" by A. M. Strachan, J. P. Leff, M. J. Goldstein, J. A. Doane, and
C. Burtt, 1985, manuscript submitted for publication.
56 A. M. Strachan et al.
11.6 and 4.7, respectively (P < 0.02). Fur- cussions around more neutral issues may
thermore, when the high EE relatives were elicit greater differences between relatives
subdivided into those who were critical, in their rate of use of supporting statements.
those who were emotionally overinvolved This thesis is supported by data from Green-
(EOI), and those who were both critical wald, Kornblith, and Hopkins (1980). They
and EOI, a similar pattern to the Miklowitz applied the marital interaction coding sys-
data was obtained (see Figure 2). However, tem to samples of interaction between schi-
it was found in this sample that a critical at- zophrenic patients and their relatives. The
titude was associated with both criticisms discussion topics were more neutral than in
and intrusions, whereas in the more chronic the other studies. They found no differ-
American sample a critical attitude was ences between low and high EE relatives on
more uniquely associated with critical be- their use of negative or neutral codes, but
havior. A study is in progress to assess low EE relatives showed more positive be-
whether different types of neutral intru- haviors (n = 25, t = 2.64; P < 0.05) such
sions are associated with critical as com- as approval, agreement, smiling, and hu-
pared with overinvolved attitudes. mor. This suggests that low EE relatives
Another interesting finding in Strachan have the potential to be more supportive
et al. 's work was that in dyads where the rel- than high EE relatives in some situations.
ative was high EE both the relative and the Overall, these studies suggest that inter-
patient used more words than in dyads actions with high EE relatives can be char-
where the relative was low EE. These fin- acterized as calmer, less verbal, with more
dings suggest that in high EE dyads both pauses, and more positive support.
participants are actively involved in the in- Although there is a reasonable level of
teraction, rather than the relative being comparability between attitudes expressed
dominant and the patient submissive. These in the Camberwell and affective style ex-
findings are similar to those reported by pressed interactionally, the distributions
Kuipers, Sturgeon, Berkowitz, and Leff revealed that the correspondence is far
(1983) who observed relatives and patients from perfect. The majority of high EE par-
talking to an interviewer and found that ents, defined as critical on the Camberwell,
high EE relatives spent 57% more time are indeed expressive of criticism but others
talking than low EE relatives, a percentage express none at all. Thus, some high EE
which is very close to the 61 % higher word parents are congruent across situations and
count observed here. Further, they found others appear to dampen or inhibit these
that the amount of silence was significantly high EE attitudes when in direct confronta-
longerin low EE pairs than in high EE pairs. tion with the patient. Currently, we are in-
Strangely enough, none of these studies vestigating whether patients living with
showed that low EE relatives made signifi- high EE individuals who express these nega-
cantly more supportive statements during tive affective attitudes when interacting
the interactions, although there were trends directly with the patient are more relapse-
in the predicted direction. This may have prone than those patients with relatives
been because the discussions focused who have the negative attitudes but do not
around emotionally charged issues and elic- express them directly to the patient.
ited critical and intrusive statements. Dis-
1. Admission interviews
1 120 1
Excluded
22
tor" other reasons"
2.PSE Excluded
46
PSE
3. CFI
4. Design 29 23
(49reL) (30 reL)
EE + EE-
15 EE + 14 22
1 EE-
(16 tam.; 29 reL) (21 reL) (29 reL)
EE + EE-
Patient Relatives
groups groups
Experimental Results
We shall start our analyses of predictor vari- lapses at the 9-month follow-up and their
ables for the course of schizophrenia (re- correlation with single EE ratings at the
lapse) with the family variables from the time of the patients' discharge. This will be
CFI, to be followed by the patient variable folowed by a series of analyses with repeat-
"nuclear symptoms" (NS) and the treat- ed assessments of EE variables (at dis-
ment variables "medication" and "group charge and the 6-month follow-up, CFI-
treatments." Finally, results from a combi- FU), eventually again related to relapse
nation of two to five variables for predic- rates (at the 9-month follow-up, REL-FU).
tions of relapse will be presented.
"Classic" EE Assessment and Relapse
Family Variables
Relapse Rates at the 9-Month Follow-up:
Before investigating the CFI variables in Control and Treatment Groups Combined
detail, we will first present results with the
"classic" CFI analysis: assessment of re- The course of illness in our patient sample is
64 B. Dulz and I. Hand
summarized in Table 1. We formed then matology was not defined as relapse when
three categories of "no relapse," "relapse," the private and (or) professional life of the
and "special course': As the operationaliza- patient was not affected by the sympto-
tion of relapse in the literature on schizo- matology.
phrenia is still a largely unresolved prob- Table 1 does not include the data of four
lem, we decided to use criteria similar to patients (which are included in the publica-
those described by Vaughn et al. (1982). tion by Kottgen et al., 1984), as these pa-
The six criteria which constitute the three tients had moved away and information had
main courses of illness in Table 1 are: come only from their relatives. The remain-
la: No psychotic symptomatology since ing 48 patients include those 5 from cate-
discharge from the hospital; Ib: psychotic gories 5 and 6 ("special course") who will be
symptomatology without deterioration in excluded from all those subsequent analy-
the quality of daily life, maximum duration ses that rely on follow-up data (resulting in
of 1 week, with or without hospital admis- a n of 43). Category 5 was reached by three
sion; lc: intermittent, short-term psychotic an n of 43). Category 5 was reached by three
symptomatology without deterioration of female patients who had not been discharg-
the quality of daily life. ed from the hospital during the REL-FU.
2a: Psychotic symptomatology without The two patients in category 6 had commit-
nuclear symptoms, for longer than 1 week, ted suicide while on the waiting list for their
without hospital admission; assigned project group.
2b: nuclear symptoms in addition to 2a. The overall outcome of approximately
3a: Readmission to the hospital for more 50% relapse in young schizophrenics during
than 1 week, but no nuclear symptoms; 3b: the first 9 months after discharge is in ac-
3a with nuclear symptoms. cordance with previous reports in the litera-
4: Persisting symptoms with deteriora- ture.
tion of the everyday quality of life.
5: Hospitalization for more than 50% of EE at Discharge and Relapse at the
the follow-up time. 9-Month Follow-up
6: Suicide. Of all our patients from the relapse cate-
Relapse was defined with regard to its in- gories 1-5 (n = 46; cf. Table 1), 25 (54%)
dividual as well as social relevance. Hospi- had relapses. The relapses occured in 14 of
tal readmission of less than 1 week is inter- the 29 (48%) patients with high EE rela-
preted as one means of preventing relapse tives, but - contrary to all previous publica-
in a short-term psychotic crisis. Likewise, tions - even in 11 ofthe 17 (65% ) from low
intermittent short-term psychotic sympto- EE families.
Table 1. Relapse rates at the 9-month follow-up: control and treatment groups combined.
Relapse
category n % n %
1a 16 33
21 43 No relapse
1b,c 5 10
2a,b 3 6
3a,b 13 27 22 46 Relapse
4 6 13
5 3 6
5 10 Special course
6 2 4
48 48
Short-Term Relapse in Young Schizophrenics 65
Course of EE Ratings over Time cause any of the EE+ patients could score
initially low on one of the two subscales.
In all subsequent analyses and figures with On the EE score, 16 of 33 initially high
EE results, we shall first report the "total" EE relatives scored low at FU, whereas
EE score (EE), followed by the results on only 5 of 30 initially low EE relatives
the subscales of emotional overinvolve- changed to high ratings at FU. Only 8 of all
ment (EOI) and criticism (CRIT). The sub- these relatives were spouses, 7 of whom
scale of hostility is not included as relatives scored low on both occasions.
never reached the cutoff point for a high Results on the total EE score resembled a
score. Simultaneously high ratings on EOI labile, state-like quality of high EE and a
and CRIT at the first assessment were only rather stable, trait-like quality of initially
observed in 4 of 63 relatives; one remained low EE ratings. The EOI and CRIT scales
high at FU only in CRIT, two scored low on showed almost identical developments of
both scales, and the fourth did not partici- ratings over time, with a particularly high
pate in the FU. stability of low EOI ratings.
Course of EE Ratings over Time Course of EE Ratings over Time:
Treatment and Control Groups Combined Control Groups
The results on all scales together are shown Whereas in the treatment groups all rela-
in Table 2: 63 relatives of 46 patients partici- tives participated in both CFI ratings, the
pated in admission interviews as well as in control groups, in particular the one with
CFI-FU. Of these 63,46 relatives came from low EE relatives, showed a much lower re-
high EE families. These 46 included 13 low test compliance: 12 of 29 (41 %) of the low
EE co-relatives from families with at least EE relatives and 3 of 21 (14%) of the high
one high EE relative. Therefore, the EE+ EE relatives refused to participate in the
ratings in Table 2 are from a total of 33 rela- second assessment. Understandably, retest
tives (46 minus 13), whereas the EE+ ra- compliance is higher in treated than in un-
tings are from 30 relatives (17 from the low treated persons, but it does not appear to be
EE control group and 13 from low EE co- as obvious as to why the dropout rate was so
relatives of high EE families). This differen- much higher in the low EE relatives.
tiation cannot be made in both subscales be-
Table 2. Course of EE ratings over time: treatment and control groups combined.
2nd CFI
EEscales
+ -
EE+ 17 16 33
EE- 5 25 30 EE
total score
63
EOI+ 7 8 15
EE
EOI- 2 46 48 emotional
overinvolvement
63
CRIT+ 10 12 22
EE
CRIT- 8 33 41 criticism
63
66 B. Dulz and I. Hand
Table 3. Natural course ofEE ratings over time: control group (high and low EE groups separately).
2nd CFI
EEscales
+ -
EE+ 6 7 13 HighEE
[EE-] 2 3 5 control grp.
EE
total score
EE- 2 15 17 LowEE
controlgrp.
EOH 2 2 4 HighEE
EOI- 1 13 14 control grp. EE
emotional
EOI- 0 17 17 LowEE overinvolvement
controlgrp.
CRIT+ 3 6 9 HighEE
CRIT- 2 7 9 control grp.
EE
CRIT- 2 15 17 LowEE criticism
control grp.
Table 3 shows the results for the high EE tives on all three scales surprisingly did not
and the low EE control group separately. show a specific treatment effect (in both
The low EE co-relatives of high EE families conditions, some 50% of initially high scor-
are now separated (the separation being in- es were low at FU, whereas low scores
dicated by brackets around EE- ratings) showed little change). Paradoxically, the
from the low EE relatives in the low EE CRIT ratings even seemed to indicate a
control group. We introduced this addition- beneficial control group effect. In the low
al subgroup, as we wanted to investigate EE co-relatives, two of eight became high
whether low EE co-relatives resemble more in the treatment groups compared with two
their high EE counterparts or the low EE of five in the control groups (Table 4).
control group in the course of ratings (cf. Comparison of high-intensity groups for
p.74). relatives (HI rel.), with 23-26 treatment
At CFI-FU, 7 of 13 initially high EE rela- sessions offered to participants, and low-in-
tives scored low, whereas only 2 of the ini- tensity groups for relatives (LI rel.), with
tially 17 low EE relatives had changed in the 8-24 sessions offered, showed no differ-
reverse direction. Results in the untreated ences between groups, and both resembled
control groups thus resembled those from the results reported before on the total EE
the total sample. The same holds true for scores.
the EOI ratings. The scale for CRIT even However, as Table 5 indicates, HI rel.
showed a decrease of high scores in two- groups seemed to specifically affect ratings
thirds of the subjects (without treatment). in both subscales; while initially high EOI
Of the five low EE co-relatives, two ratings decreased in this group, initially low
changed to high ratings. CRIT ratings increased (the LI rel. group
did not show this effect).
Course of High EE Ratings over Time:
Treatment and Control Groups
Course of EE Ratings and Relapse
Direct comparison of treated (n = 20) and
untreated (n = 13) initially high EE rela- Since EE ratings at discharge did not prove
Short-Term Relapse in Young Schizophrenics 67
Table 4. Course of high EE ratings over time: treatment and control groups.
2ndCFI
Treatment groups Control groups
EEscales EEscales
+ - + -
EE+ 11 9 20 6 7 13 EE
total score
[EE-j 2 6 8 2 3 5
28 18 46
EOI+ 5 6 11 2 2 4 EE
emotional
EOI- 1 16 17 1 13 14 overinvolvement
28 18 46
CRIT+ 7 6 13 3 6 9
EE
CRIT- 4 11 15 2 7 11 criticism
28 18 46
Table 5. Course of high EE ratings over time: effects of high-intensity vs low-intensity relatives
groups.
2nd CFI
Treatment groups Control groups
(LI pat. groups) (HI pat. groups)
EEscales EEscales
+ - + -
EE+ 5 5 10 6 4 10 EE
3 1 4 5 total score
[EE-j 1 2
13 15 28
EOI+ 2 5 7 3 1 4 EE
emotional
EOI- 1 5 6 0 11 11 overinvolvement
13 15 28
CRIT+ 4 3 7 3 3 6
EE
CRIT- 3 3 6 1 8 9 criticism
13 15 28
68 B. Dulz and I. Hand
the total EE score), then in low EE families no relapse, but two-thirds changed to low
(n = 17 relatives). even when patients relapsed!
Results from High EE Families (Treatment Do such diverse developments of the
and Control Groups Combined): three EE scales over time question the va-
lidity of the (most commonly used) total
As already mentioned, some 50% of the score?
high EE relatives changed to low EE total
scores at FU, independently of relapses in Results from Low EE Families
patients. Initially low EE co-relatives re- (Control Group):
mained the same only when patients did not Of the 17 relatives in the low EE control
relapse; three of four initially low EE co- group (10 with a relapsed patient), 15 re-
relatives of the patients who relapsed mained the same at FU on all three scales.
changed to high EE. It is difficult to inter- The other two relatives, both with a re-
pret this result, as the initially low EE rela- lapsed patient, remained low in EOI, but
tives in the control group in the vast majori- became high in CRIT.
ty remained low, even when patients re-
lapsed (Table 6).
In contrast to high total scores, high EOI Patient Variables
scores showed a positive correlation be-
tween relapse and their development over Nuclear Symptoms and Relapse
time. Four of six initially high EOI relatives All seven patients with nuclear symptoms
remained the same at FU when patients re- (NS) at discharge (two) or at discharge and
lapsed, as compared with four of ten, when FU (five) "relapsed" during FU, five of
patients had suffered no relapse. Low EOI them with persisting symptoms (relapse cat-
ratings remained the same, independently egory 5).
of relapse. Of the 36 patients without NS at dis-
Results became even more inconclusive charge, 15 (42%) relapsed. Of the 21 pa-
with the CRIT ratings: high ratings changed tients without NS at discharge and no re-
to low in about 50% when patients showed lapse, only 1 developed NS at FU.
2ndCFI
High EE relatives of patients
EE+ 10 9 19 6 7 13 EE
total score
[EE-] 1 9 10 3 1 4
29 17 46
EOI+ 4 6 10 4 2 6 EE
emotional
EOI- 1 18 19 2 9 11 overinvolvement
29 17 46
CRIT+ 6 6 12 3 6 9
EE
CRIT- 3 14 17 2 6 8 criticism
29 17 46
Short-Term Relapse in Young Schizophrenics 69
Of the 22 patients with relapse, about taken into consideration. In fact, 9 of 12 pa-
one-third (n = 8) showed no NS at dis- tients who relapsed in spite of CNM com-
charge and FD, the second third (n = 7) NS plained about side effects, whereas only 6 of
only at FD, and only the last third (n = 7) 11 who received CNM and did not relapse
NS at discharge or on both assessments. expressed the same complaint.
Group treatments
HI pat. group LI pat. group
(LI rei group) (HIrel group)
Relapse No relapse
+ - + -
i::'"<) >75% 2 5 0 1
§ i::'"
co
<) ·3co 50%-75% 0 0 0 0
!:i ~
0.. <50% 1 0 2 3
;:::
0
....
OJ) 3 5 8 2 4 6
..c::
......
.~ >75% 1 3 0 2
<) '"
<)
c..> .~
I:: co 50%-75% 2 2 2 0
.~
V
0.. p::: <50% 0 0 0 2
8
0
U 3 5 8 2 4 6
70 B. Dulz and I. Hand
not relapse (cf. Table 7, upper section). These fered. It appears that patients' compliance
short-term relapse data do not show better with treatment motivated their relatives to
results for high-intensity treatments (with participate regularly rather than the other
higher appointment compliance of patients) way around.
than for low-intensity treatments (with also
lower appointment compliance of patients). Multivariate Prediction of Relapse
As the relatives of LI pat. groups them-
selves were offered HI reI. groups., with As we have seen so far, the single variables
regard to family problems, this may have investigated in most analyses separated the
been a compensation: Every single family total patient sample into two or three al-
unit in both patient groups received the most equally sized subsamples - with the
same total amount of treatment. exception of the presence of NS "at dis-
If HI reI. groups were to have such a com- charge." Can the combination ofthese var-
pensatory effect, this could only be ex- iables enhance their predictive power?
pected from high compliance of the rela-
tives. As data in Table 7 (lower section) Relapse: Family and Treatment Variables
show, this was not the case.
Whereas most patients in HI pat. groups Neither CNM nor group therapy alone spe-
also showed optimum compliance and cifically affected relapse rates. If we regard
those in LI pat. groups showed low com- both together, a third variable, high EE,
pliance (i.e., they intensified by their com- implicitly (by design) affects the outcome.
pliance the separation of treatment condi- A look at the data of patients from high
tions by design), the relatives did not show EE families only (treatment and control
the same response pattern. We found that groups combined) reveals that 15 of them
in the HI reI. groups the four relatives of pa- had suffered no relapse, 9 of whom had
tients who did not relapse were equally been in treatment groups. Of the nine with
distributed to both extreme pools of com- and the six without group therapy, one-
pliance, whereas the two relatives of re- third in each condition had received no me-
lapsed patients showed medium compli- dication. Of the patients in group therapy,
ance. In the LI reI. groups, no relative at- there were only five who (together with one
tended less than 50% of the sessions of- relative) attended more than 50% of the
fered! Four of the eight relatives reached sessions offered, whereas four did not (cf.
medium, the other four optimum compli- Table 8).
ance. In the treatment groups, a combination
With regard to the single family units, it of EE+, CNM, and group therapy (Table
became clear that HI paULI reI. treatment 8) only prevented relapse in 6 of 11 patients.
produced by far the best compliance of This result seems to be even worse than for
both family members in the treatment of- patients from high EE families with CNM,
I EE ratings
Patients with CNM Patients without CNM
- 21 10 31
25 21 46
All groups
Relapse / Relapse
+ - + -
+ 2 10 12 + 2 1 3
- 12 5 17 - 9 5 14
14 15 29 11 6 17
Relapse Relapse
+ - + -
+ 0 6 6 + 2 4 6
- 7 3 10 - 5 2 7
7 9 16 7 6 13
Relapse Relapse
+ - + -
+ 0 5 5 + 0 1 1
- 3 0 3 - 4 3 7
3 5 8 4 4 8
HI pat. therapy group LI pat. therapy group
Fig. 2. Prediction of relapse by Family Compliance Index (FCI) for all groups.
72 B. Dulz and I. Hand
Eleven patients had no NSd and group 2. Regular, high-potency neuroleptic med-
therapy, and only three relapsed. Six pa- ication at least during half of the obser-
tients had no NSd, CNM without SE, and vation time.
group therapy, and none of them relapsed. 3. No side effects of neuroleptic medica-
However, a fourth and possibly even a fifth tion.
variable may have influenced this outcome. 4. Regular participation in patients'
These six patients were from a total sample groups.
of seven, of whom two relatives participated 5. Regular participation in relatives'
regularly in group treatment; also, five of groups.
these six patients attended the HI pat. 6. If group treatment is not offered, use of
groups. Obviously, introduction of the pa- alternative treatment modalities (thera-
tient variable increased plurivariate pred- peutic hostels, etc.).
ictability of relapse. A high FCI was shown by 6 ofthe 16 high
Finally, we would like to suggest a multi- EE families in the treatment groups, and
variante "Family Compliance Index" (FCI) none of the respective patients relapsed. Of
for prediction of the course of illness from the 13 high EE families from the control
the compliance behavior of patients and group 6 showed a high FCI; two of the re-
relatives with regard to the treatment of- spective patients relapsed.
fered. This FCI consists of the following six Of the 19 low EE families, only 3 showed
variables, four of which have to be present a high FCI - again indicating the specificity
in families with group therapy offered and of low EE families. Two of these three pa-
three in those without such an offer to tients were among the 11 who suffered re-
achieve a "high" rating: lapse.
The results of the systematic application
1. Regular outpatient psychiatric treat- of FCI on our total patient sample and its
ment after discharge. subgroups is shown in Figure 2.
References
Anderson, C., Hogarty, G., and Reiss, D. New developments in interventions with fami-
(1981). The psychoeducational family treat- lies of schizophrenics. San Francisco: Joessey-
ment of schizophrenics. In M. Goldstein (Ed.) Bass.
Short-Term Relapse in Young Schizophrenics 75
Berkowitz, R., Kuipers, L., Eberlein-Fries, R., Leff, J., Kuipers, L., and Berkowitz, R. (1983).
and Leff, J. (1981). Lowering expressed emo- Intervention in families of schizophrenics and
tion in relatives of schizophrenics. In M. Gold- its effect on relapse rate. In W. McFarlane
stein (Ed.) New developments in interventions (Ed.) Family therapy in schizophrenia. New
with families of schizophrenics. San Francisco: York: Guilford.
Jossey-Bass. Liberman, R., Wallace, c., Vaughn, c., and
Bleuler, M. (1972). Die schizophrenen Geistes- Snyder, K. (1980). Social and family factors in
storungen. Stuttgart: Thieme. the course of schizophrenia. Toward an inter-
Ciompi, L., and Muller, C. (1976). Lebensweg personal problem solving therapy for schizo-
und Alter der Schizophrenen. Berlin, Heidel- phrenics and their families. In: Strauss, J.,
berg, New York: Springer. et al. (Eds.) The psychotherapy of schizophre-
Falloon, I., Boyd, J., and McGill, C. (1984). nics. New York: Plenum.
Family case of schizophrenia. A problem-solv- Vauhn, c., and Leff, J. (1976). The influence of
ing approach to the treatment of mental illness. family and social factors on the course of psy-
New York: Guilford. chiatric illness. A comparison of schizophrenia
Hand, I. and Gross, J. (1980). Diagnostik und and depressed neurotic patients. British Jour-
Therapie von hochgradig ruckfallgefiihrdeten, nal of Psychiatry 129: 125 -137.
fruh erkrankten schizophrenen Patienten. Vaughn, c., Snyder, K., Simon, J., Freeman,
Finanzierungsantrag SFB 115, 1981-1983 Uni- W., and Falloon W. (1984). Family factors in
versitiit Hamburg. schizophrenia relapse. Replication in Cali-
Huber, G., Gross, G., and Schuttler, R. (1979). fornia of British research on expressed emo-
Schizophrenie. Berlin, Heidelberg, New York: tion. Archive of General Psychiatry 41:
Springer. 1169-1177.
Kottgen, C., Sonnichsen, I., Mollenhauer, K., Wallace, C. (1982). The social skills training pro-
and Jurth, R. (1984). Results of the Hamburg ject of the Mental Health Clinical Research
Cambcrwell Family Interview Study, I-III. Center for the study of schizophrenia. In Cur-
International Journal of Family Psychiatry, 5: ran, J., Monti, P. (Eds.) Social skills training: a
61-94. practical handbook for assessment and treat-
ment. New York, Guilford.
76 B. Dulz and I. Hand
Comment on Chap. 5*
C. Vaughn high persisting symptoms appeared to be
less responsive to social influence than
The Hamburg investigators admit to being other patients, perhaps because of a dif-
puzzled by their own results, which appear ferent type of schizophrenia, more biologi-
to refute the main findings of all EE-based cally based. Yet, the Hamburg investiga-
studies to date. None of the factors previ- tors included patients with high persisting
ously identified as offering a measure of symptoms in the "relapsed" group. Thus,
protection against schizophrenic relapse the allocation of patients to "relapse" and
did so in this study: neither regular medica- "no relapse" categories differed considera-
tion, nor relatives' low EE, nor family ther- bly from past practice. The broader out-
apy. Particularly surprising is the high rate come criteria employed in Hamburg are not
of relapse in the low EE group, irrespective necessarily inferior to a criterion of out-
of medication compliance. In previous stu- come which is narrowly defined, but they
dies, the rate of relapses for low EE patients are different and should not be viewed as
on regular medication has been negligible. equivalent. Meaningful comparisons with
These contradictory conclusions clearly previous results cannot be made in the ab-
warrant additional consideration and com- sence of comparable criteria.
ment. A second major difference concerns an
That this was a well-intentioned and care- unreported but crucial aspect of the Ham-
fully executed study is not in doubt. How- burg study: the fact that a majority of pa-
ever, there were major differences in the tients, and low EE patients in particular,
design and methodology of the Hamburg did not live at home throughout the follow-
study, vis-a-vis previous EE studies, which up period. Indeed, low EE patients were
made it less of a "replication" than one much more likely than high EE patients to
would have wished. These may be sum- live away from parents and to have low
marized as follows: face-to-face contact (Kottgen, 1984, per-
1. Differences in the relapse criteria used sonal communication). The failure of the
to define outcome Hamburg investigators to either acknowl-
2. Unreported differences in the propor- edge this fact or to allow for it in the collec-
tion of patients who were living contin- tion and analysis of data casts doubt on
uously at home during the follow-up pe- many of the conclusions concerning low EE
riod families and relapse. Results from the Cali-
3. Unreported differences in the proce- fornia EE study emphasized the impor-
dures used to allocate families to high tance of the "at-home" factor. In the Cali-
EE and low EE groups. fornia study, unlike earlier British studies, a
A fuller account of these differences may sizeable minority of the total sample lived
explain at least in part the discrepant results away from home for some part of the fol-
obtained. low-up period. Because the impact of the
Firstly, the Hamburg relapse criteria dif- key relatives might be "diluted" in these
fered in several important respects from cases (depending also on patterns of con-
those employed in earlier EE studies, de- tact), it was thought essential to consider
spite the author's claims to the contrary. the results for the at-home group separately
Past EE studies have used changes in spe-
cifically schizophrenic symptomatology to
define relapse, without regard to days spent * A copy of Chap. 5 was not available to Christine
in the hospital or quality of social function- Vaughn when she wrote her contribution to this
ing in the follow-up period. Furthermore, book. As results seem to question previous CFI
publications with regard to their generalizability
patients who never recovered from the key to young schizophrenics, we greatly appreciate
admission episode were excluded from sub- that she has accepted the invitation for her special
sequent analyses of the relationship be- comments. It was agreed beforehand that the
tween relatives' EE scores and their own re- authors would not comment upon these com-
lapse (Vaughn et al. 1984). Patients with ments in this volume.
Short-Term Relapse in Young Schizophrenics 77
from the rest of the sample. As reported ficient information. The households in que-
elsewhere (Vaughn, Snyder, Jones, Free- stion might well be high EE, and certainly
man, and Falloon, 1984), the relationship should not be treated as low EE. Such
between EE and relapse was predictably misallocations are likely to have contrib-
strongest for patients living at home con- uted to the increased rate of "relapse" in the
tinuously, although there was still a signifi- Hamburg low EE group.
cant relationship for the sample as a whole. In summary, there are a number of im-
However, the significant relationship disap- portant differences in design and methodol-
peared if one considered only the patients ogy between the Hamburg study and previ-
who lived away for some part of the follow- ous EE studies which call into question its
up period. High EE patients were more status as a "replication" study. It is neces-
likely to remain well if away from home, sary to look no further than these differ-
while low EE patients were more likely to ences for possible explanations of discre-
relapse. The interpretation of the low EE pant results regarding EE and relapse.
data was that the benign influence of the Other puzzling findings, such as the failure
low EE relative was diminished if the pa- of medication to protect patients against re-
tient lived away from home, with other re- lapse and the absence of a specific effect for
lationships and other stresses (including life family therapy, warrant a closer examina-
events) assuming increased importance. tion, which is beyond the scope of this com-
These results have important implications mentarv. However, the low levels of com-
for the Hamburg study. Given the high pro- pliance with family treatment may be parti-
portion of low EE patients living away from ally explained by the fact that many patients
home and exposed to various nonfamilial (especially low EE patients) lived away
influences, it seems quite unjustified to sug- from home, as well as by the clinicians' que-
gest that their high relapse rates may be due stionable decision to delay family therapy
to relatives who are "burnt-out" or "hypo- until the time when a treatment "group"
critical"! was complete. An approach in which pa-
A third major difference was the Ham- tients and relatives may wait weeks or even
burg decision to allocate to the low EE months for treatment to begin does not
group patients from households in which a seem to provide an optimal test of family
key relative who was not interviewed was therapy.
described by an interviewed low EE relative Finally, it is not an implicit assumption of
as being critical/hostile or overinvolved the CFI research that EE levels are constant
(Kottgen, 1984, personal communication). over time. This issue is discussed at some
This is not appropriate, even ifthe noninter- length elsewhere in this book (Chap. 8). In
viewed relative was in low contact with the most respects, the Hamburg results are con-
patient. In previous EE studies, such cases sistent with earlier findings concerning the
would have been dropped because of insuf- stability of EE.
References
Vaughn, C. E., Snyder, K. S., Jones, S., Free- plication in California of British research on ex-
man, W. B., and Falloon, I. R. H. (1984). pressed emotion. Archives of General Psychia-
Family factors in schizophrenics relapse: Re- try, 41,1169-1177.
6. Emotional Atmosphere in Families of Schizo-
phrenic Outpatients: Relevance of a Practice-
Oriented Assessment Instrument
G. Buchkremer, H. Schulze-Monking, L. Lewandowski, and C. Wittgen
Introduction
The Camberwell Family Interview (CFI), and Leff (1976 a) obtained with the CFI can
the measure used to assess "expressed emo- be replicated using a simpler measurement
tion" (EE), can hardly be used in routine instrument. An appropriate survey instru-
psychiatric work since the time required for ment, the Munster Familiy Interview
relatives and raters with this test instrument (Munsteraner Familienbogen, MFB), is de-
is very great (about 4-5 h per rating). In ad- scribed in this paper. This interview not
dition, the amount of effort necessary to ar- only provides a measure of the emotions ex-
rive at a sufficiently high interrater reliabili- pressed by the individual family members,
ty during rater training is hardly possible but also registers the entire emotional fami-
under the given conditions. ly atmosphere (EFA) and might therefore
For psychiatric practice, the question be an alternative measure of the EE con-
arises as to whether the results of Vaughn struct.
Method
expenditure of time than the CFI. By means
Munster Family Interview (MFB)
of this instrument, nine qualities of feeling
The MFB is a practicable survey instrument (EFA factors) in the emotional family at-
which requires both less rater training and mosphere are surveyed (Table 1).
Results
For the EFA factors of criticism, over-
Reliability
protectiveness, and rejection, a good de-
Ten advanced psychology students were gree of reliability resulted, and for the EFA
trained for 24 h in the rating of the EFA fac- factors of hostility, resignation, predomi-
tors. The training was carried out using nance, and acceptance, a moderate degree
videotapes of family interactions. A loss of of reliability. Low Kappa coefficients were
information had to be accepted as the fami- calculated for the EFA factors of indiffer-
ly atmosphere can be experienced more viv- ence and warmth. For the reasons men-
idly during the home visit than on a video- tioned above, they were difficult to rate and
tape. In this way, the EFA factor indiffer- had only a low frequency of moderate or
ence and warmth were hard to rate since high degree rating but a good agreement.
their rating is especially based on nonverbal (In a study which is currently in progress, a
behavior which is difficult to assess from reliability check will be carried out in the
videotapes. context of home visits.)
Ratings of the EFA factors were done in-
dividually by each rater, and overall 18 fam-
Validity
ily members were rated. To test reliability a
dichotomy was used, contrasting a moder- Different aspects of the validity of the MFB
ate or high rating with a mild or "no evi- will be investigated below. According to the
dence" rating. The results are shown in results of Vaughn and Leff (1976 b), criti-
Table 2. cism, and to a small extent, emotional over-
Emotional Atmosphere in Families of Schizophrenic Outpatients 81
Table 2. Interrater Reliability of the EFA Factors (n = 18).
Kappa Agreement!
Table 3. Phi Correlation Coefficients Between EFA Factors and Relapse on I-Year Follow-up
(n = 23)
Impairment
Attention Compul- Delusion Hallu- Ego Affective
EFA disorder sion cination disorder disorder
factors
Emotional Family Atmosphere and found to have prognostic value , also showed
Psychopathology of the Patient a correlation with disorders of attention.
The paranoid hallucinatory syndrome
Marked involvement of the relatives in the
was not correlated with the EFA factors of
patient'slife can be understood as a possible
criticism or indifference. However, in the
reaction of the relatives to a schizophrenic
delusions there was a significant correlation
disorder (coping strategies). The correla-
with the EFA factor of rejection. Hallucina-
tion between the EFA and the psychopa-
tions correlated with low levels of warmth
thological status of the patient will there-
and acceptance.
fore be investigated next.
The following investigation is intended to
The psychopathological status of the pa-
clarify whether there is a correlation be-
tient was scored by third-person rating
tween the cognitive disorders rated by the
using the AMDP system (a German psychi-
patients themselves and the EFA.
atric rating system; AMDP 1982) and by
The patients (n = 24) answered the short-
self-rating using the Frankfurt syptom in-
ened form of the FBF by which the subjec-
ventory (FBF; Siillwold 1977).
tive experience of thought and perception
processes can be surveyed (Siillwold, 1977,
Results of the Third-Person Rating
(AMPD)
1983). The shortened form of the FBF as-
sesses three factors.
The EFA factor of criticism displayed sig- Factor A: Disturbance of perception and
nificant correlations with three areas of psy- movement activity
chopathological disorders (attention, ego, Factor B: Disturbance of thought and
and emotional disorders). The EFA factor speech
of indifference, which (like criticism) was Factor C: Anxiety and coping reactions
Table 5. Rank Correlation Coefficients (Spearman) Between FBF Scores and EFA Factors (n = 24)
EFA
FBF FBFscore FBFfactorA FBF factor B FBFfactorC
Discussion
In contrast to the CFI, the MFB proved to teria of doubling the neuroleptic medica-
be a practical instrument for rating the en- tion indicates that the more chronic patients
tire EFA in the presence of all family mem- who are undergoing chronic neuroleptic
bers and of the patient. The results indicat- treatment are likely targets of indifference.
ed a satisfactory criterion validity. The in- In patients with a mainly critical family at-
terrater reliability was sufficient. mosphere, a long period of neuroleptic
With regard to prognostic criteria, the re- treatment was rarer. In these patients, there
sults of the MFB agreed with previous CFI was a more frequent fresh prescription of
research. As noted with the CFI, relapse neuroleptics in cases of crisis. Furthermore,
was associated with criticism expressed by they also experienced a subjective feeling of
the relatives. The present study confirms relapse significantly more often.
the results of Brown et al. (1972) as well as With some caution, these results can be
Vaughn and Leff (1976 b). interpreted in the following way: A critical
Surprisingly, an indifferent attitude of the family atmosphere is too great a strain for
relatives with regard to the patient likewise many patients, above all when they are
indicated a raised risk of relapse of the pa- under chronic neuroleptic treatment so that
tient. One reason for this appears to be that their vulnerability threshold is exceeded
the MFB assesses not only the family mem- and a relapse occurs. A high measure of in-
bers who are interacting most intensively difference in the family indicates that self-
with the patient but also the remaining rel- help potentials are absent in these families
atives. Evidently, both an emotionally in- and in these patients so that pychiatric in-
tense as well as a low-tension family atmos- terventions (e.g., rehospitalizations) be-
phere can entail a raised risk of relapse. come necessary to a greater extent in times
Great significance is to be accorded to of crisis.
this finding since it indicates that the "tight- In the investigation of the connection be-
rope walk" between overstimulation and tween the symptoms of the patients and the
understimulation as described by Wing EFA, significant correlations were revealed
(1976) also applies to the EFA of schizo- with "criticism" and the psychopathological
phrenic patients. Thus, not only emotional symptom areas of attention, ego, and emo-
overinvolvement in the families of schizo- tional disorders. In addition, disorders of
phrenic patients is to be avoided, but also a attention also correlated with indifference
lack of involvement is to be prevented. This of the relatives.
means that family therapies which empha- Analogous findings resulted when the ex-
size more reserve or more indifference by tent of the disorders of cognitive processes
the relatives toward their unwell family rated by the patients themselves as well as
member must be viewed with caution. their coping reactions were related to the
The finding that an indifferent family at- EFA.
mosphere is associated with the relapse cri- These findings indicate a reciprocity of
84 G. Buchkremer et al.
the correlations between the EFA and the mission and EE status. This is probably be-
psychopathological status of the patients. cause our patients were examined 6 months
The correlation between the EFA and the after their discharge from the hospital. The-
emotional expression behavior of the pa- refore, the range of symptoms from few to
tients could already be demonstrated in an severe was broader than in the investiga-
earlier investigation of Brown et al. tions of the authors mentioned above, who
(1972), Vaughn and Leff (1976 b), and examined patients on admission, when they
Miklowitz et al. (1983), who reported no as- normally all have severe symptoms.
sociation between clinical symptoms on ad-
References
AMPD. (1982). Das AMPD-System. Manualzur suchung zum EE-Index. Aktuelles Forum Psy-
Dokumentation psychiatrischer Befunde (4th cho (Suppl. I). (pp. 9-10). Erlangen: Perimed.
ed.). Berlin Heidelberg New York: Springer. Mikiowitz, D., J., Goldstein, M. J., and Falloon,
[English translation: Guy, W., and Ban, T. A. J. R. H. (1983). Premorbid and symptomatic
(Eds.) The AMDP system, Berlin, Heidelberg, characteristics of schizophrenics from families
New York: Springer (1982)]. with high and low levels of expressed emotions.
Brown, G. W., Birley, J. L., and Wing, J. K. Journal of Abnormal Psychology, 92,
(1972). Influence offamily life on the course of 359-367.
schizophrenic disorders: A replication. British Siillwold, L. (1977). Symptome schizophrener
Journal of Psychiatry, 121,241-58. Erkrankungen. Uncharakteristische Basissto-
Buchkremer, G., and Fiedler, P. (1982). Ange- rungen. Berlin, Heidelberg, New York: Sprin-
hOrigentherapie bei schizophrenen Patienten. ger.
In Helmchen, H., Linden, M., and Ruger, U. Siillwold, L. (1983). Schizophrenie. Stuttgart:
(Eds.), Psychotherapie in der Psychiatrie. Ber- Kohlhammer.
lin, Heidelberg, New York: Springer. Vaughn, C., and Leff, J. (1976 a). The measure-
Buchkremer, G., and Lewandowski, L. (1984). ment of expressed emotion in the families of
Therapeutische Gruppenarbeit mit AngehOri- psychiatric patients. British Journal of Social
gen schizophrener Patienten. In: C. Anger- and Clinical Psychology, 15, 157-165.
meyer, and A. Rinzuen (Eds.), Die AngehOri- Vaughn, C., and Leff, J. (1976 b). The influence
gengruppe. Stuttgart: Enke. of family and social factors on the course of psy-
Buchkremer, G., Lewandowski, L., and Fiedler, chiatric illness: A comparison of schizophrenic
P. (1982). Emotionale Interaktionsmuster in and depressed neurotic patients. British Jour-
Familien schizophrener Patienten. Eine Unter- nal of Psychiatry, 129, 125 -137.
7. The Marriages and Interaction Patterns
of Depressed Patients and Their Spouses:
Comparison of High and Low EE Dyads
J. M. Hooley and K. Hahlweg
Introduction
Although we can now be relatively confi- titude expressed during an interview has a
dent that there is indeed a reliable associa- corresponding behavioral analogue in na-
tion between family levels of expressed turalistic patient-relative interactions. Only
emotion (EE) and relapse rates in schizo- in recent years has the validity of this as-
phrenic and depressed patients, a word of sumption actually been subjected to empiri-
caution is perhaps appropriate. Despite the cal scrutiny (see Chap. 4). Results of a study
encouraging results of recent intervention published in 1983 by Valone, Norton,
work, we are still some distance from a full Goldstein, and Doane first suggested that
understanding of what EE actually is and there might indeed be differences between
how it might operate to influence the pro- the interactions of families which varied ac-
cess of relapse. Discussions of the content of cording to EE level. Using a sample of 52
interviews conducted with high and low EE disturbed but non psychotic adolescents
relatives, such as the one provided by and their families, these investigators were
Vaughn in Chap. 8, are of clear value in in- able to demonstrate that in affectively
creasing our knowledge of the emotional charged situations, parents who expressed
responses of families and in enhancing our high EE attitudes made significantly more
understanding of how they cope with a psy- criticisms during face-to-face interaction
chiatrically ill individual. with their offspring than parents who were
A second approach to understanding EE low in EE.1
concerns systematic investigation of the be- Valone et al.'s results are important be-
havior of high and low EE relatives, in an cause they indicate that a high EE attitude
effort to learn more about what goes on might be associated with high levels of criti-
when family members are involved in direct cal behavior toward a patient. Additional
interactions with an ill patient. Despite the but rather weak support for behavioral dif-
importance of this avenue of research, only ferences between high and low EE relatives
in very recent years have investigators also comes from a study conducted by Kui-
turned their attention toward the study of
the behavioral correlates of high and low 1 While such data are encouraging, two minor
EE attitudes. methodological issues should be noted. First, the
Clearly though, if high EE relatives have subjects used in the study were not adult psychia-
a negative influence on the course of a pa- tric patients (the population on which all previous
tient's illness, it is likely that some differ- EE research has focused) but were disturbed and
ences between high and low EE families possibly "preschizophrenic" adolescents.
must exist to trigger the relapse process. Second, the assessment of levels of EE was made
Indeed, this is an assumption implicit in all by rating the UCLA parental interview and not
EE work. At the present time, however, we the CFI which is the standard EE assessment
instrument. How much effect the use of a dif-
have relatively little information about the ferent interview has on the ratings of EE is not
types of behavior or behavior patterns as- clear, but nevertheless this is a feature of the
sociated with high and low EE attitudes. study which should be borne in mind in any inter-
The EE literature assumes that a critical at- pretation of the data.
86 J. M. Hooley and K. Hahlweg
pers, Sturgeon, Berkowitz, and Leff that some real difficulties do exist within the
(1983), which investigated rates of talking relationships of patients and high EE family
and durations of looking in high and low EE members. The physiological data referred
relatives. Although no differences between to earlier (see Chap. 2) also lend further
patients were apparent, high EE relatives support to this view. Since there is now evi-
did spend more time talking to patients and dence that high family levels of EE are asso-
less time looking at them than their low EE ciated with elevated rates of relapse in de-
counterparts. Such findings are consistent pressed patients (see Chap. 2), it is becom-
with the view of Berkowitz, Kuipers, Eber- ing clear that EE influences are not specific
lein-Vries, and Leff (1981) that low EE rel- to schizophrenia. Information about the in-
atives are better listeners. terpersonal relationships and interaction
To date, perhaps the best study of the in- patterns of depressed individuals and their
teractional correlates of EE in the families relatives is thus important and worthy of
of schizophrenics is that of Miklowitz and discussion here because of its potential val-
his coUegues (Miklowitz, Goldstein, Fal- ue for furthering our understanding of the
loon, and Doane, 1984). In this investiga- nature of EE. Since no data currently exist
tion, not only did high EE parents differ which examine such issues in schizophrenic
from low EE parents - the former showing samples, a chapter on depressed patients
more emotional negativity toward their off- has consequently been included in this
spring during face-to-face interactions - book.
but within the high EE group differences One principal difference between schizo-
were also found between high EE critical phrenics and depressed patients, however,
and high EE overinvolved parents. Over- is that the latter are much more likely to be
involved parents were much more likely to married. Their key relative is thus most
use neutral-intrusive statements than high likely to be a spouse. This provides an ideal
EE critical parents. Thus, the pattern of in- opportunity for the assessment of the rela-
teraction exhibited in schizophrenic fami- tionship between the patient and relative
lies may differ not only according to the EE using psychometrically sound inventories of
level of the relatives, but also according to marital satisfaction and for examining the
whether there is marked evidence of emo- association between marital harmony and
tional overinvolvement. levels of EE. This chapter will focus on the
All three studies of the behavioral corre- marital satisfaction levels reported by high
lates of EE described above were con- and low EE dyads2 within a depressed sam-
ducted using schizophrenic (or "preschizo- ple. In addition, data will be presented con-
phrenic") patients and their families. The cerning the interaction styles typical of such
behavioral data from these samples, togeth- groups. Finally, some remarks relevant to
er with the interview data presented by intervention work with high EE families
Vaughn in Chap. 8, clearly suggest that all is will be made, based on the results describ-
not well within high EE families and imply ed.
Subjects
The data presented in this chapter are based videotaped subgroup and the full sample
on a total sample of 44 patients and their (see Hooley, 1984) revealed that there was
spouses, all of whom were recruited while no tendency for the 30 videotaped couples
the patients were in a hospital suffering
from an episode of major depressive dis-
2 Throughout this chapter, the term high EE cou-
order. Since not all of these couples agreed
ple or high EE dyad will be used to refer to a part-
to be videotaped, however, behavioral data nership involving a depressed patient and a high
are available on only 30 dyads. Demo- EE spouse. The term low EE couple will be used
graphic data and data concerning EE levels in a similar way to denote the relationship be-
and marital satisfaction ratings are based on tween a depressed patient and his/her low EE
the full sample. Comparisons between the spouse.
The Marriages and Interaction Patterns 87
Table 1. Demographic Characteristics of Patients and Spouses Contributing Data to the Study
Group M SD
Patients (n = 44)
Age 48.2 11.7
DAS 103.6 17.8
Beck 26.0 11.0
Social class 19.6 11.1
Children 2.3 1.1
Length of marriage (years) 21.8 13.0
Spouses (n = 44)
Age 48.8 11.9
DAS 106.0 16.6
Beck 5.6 3.9
to be in any way untypical of the total re- from three psychiatric hospitals in or near
search sample in their EE levels or their Oxford, England and, as can be seen from
level of reported marital satisfaction. Table 1, are fairly representative of a mid-
All participating patients were recruited dle-aged, middle-class population.
Inclusion Criteria
To be accepted into the study, patients were tory (BDI) scores (Beck, Ward, Mendel-
required to meet the criteria of the Present sohn, Mock, and Erbaugh, 1961) confirm
State Examination (PSE; Wing, Cooper, that the patients recruited were generally
and Sartorius, 1974) and be cases of depres- severely depressed, their mean BDI score
sion at ID level 5 or above. In addition, it being 26.0. In contrast, their spouses
was also necessary for each patient to meet showed the low BDI scores typical of non-
the Research Diagnostic Criteria (Spitzer, depressed individuals (mean BDI for
Endicott, and Robbins, 1978) for major de- spouses = 5.6).
pressive disorder. Beck Depression Inven-
LevelsofEE
Spouses were assigned to the high or the tape data were available actually made ex-
low EE groups by a median split of the num- actly six critical comments, the median split
ber of critical comments made. Thus, resulted in high and low EE groups near-
spouses were placed into the high EE group ly identical to those recognized by Brown,
if they made seven or more critical com- Birley, and Wing (1972) and Vaughn and
ments; those who made six comments or Leff (1976) and found to be significantly as-
less were categorized as being low in EE. sociated with relapse rates in schizophrenic
Since none of the spouses for whom video- populations.
HighEE LowEE
Measure (n = 24) (n = 18) P
Age M 44.4 53.3 <0.02
SD 9.5 12.8
Length of marriage M 17.7 25.6 <0.05
SD 10.4 14.6
Children M 2.3 2.4 NS
SD 0.9 1.5
Social class M 17.9 21.7 NS
SD 11.2 11.1
BDIofspouse M 5.7 5.1 NS
SD 4.4 3.1
BDlofpatient M 25.9 26.2 NS
SD 11.1 11.3
Warmth" M 1.9 3.9 <0.001
SD 1.4 1.1
Hostility" M 1.6 0.4 <0.001
SD 1.1 0.9
Positive remarks" M 1.7 2.6 NS
SD 2.3 1.7
D AS of spouse M 99.2 112.4 <0.02
SD 16.0 13.7
DAS of patient M 97.4 111.6 <0.05
SD 12.5 20.7
"CFI rating.
ment Scale (DAS), a self-report inventory spouses also did not differ according to EE
of marital satisfaction developed by Spanier level. Thus, high EE spouses do not appear
in 1976, high EE spouses reported being to be critical simply because they have more
less satisfied with their marriages than low severely depressed partners or because they
EE spouses. This is reflected by their lower themselves feel more depressed than low
DAS scores (99.2 vs 112.4, t = -2.52, P < EE spouses, nor does having a highly criti-
0.02). cal spouse seem to influence the level of de-
Some variables, on the other hand, did pressed mood reported by the patient. The
not discriminate between spouses differing correlation between the BDI score of the
in EE levels. These variables included so- patient and the number of critical remarks
cial class, number of children, and also the made by the relative was 0.14 (NS). The
BDI scores of both patients and spouses. correlation between the BDI score of the
The findings for BDI scores are interesting spouse and the number of critical comments
since they suggest that the intensity of the he or she makes is even lower (r = -0.05,
depression reported by the patient is not it- NS). The amount of criticism made by the
self directly related to the number of criti- spouse thus seems to be independent of
cisms made by the spouse. Moreover, the both the BDI score of that spouse and ofthe
level of the depressed mood reported by BDI score of their patient-partner.
60
50
40
30
20
10
-10 Patient
- 20 Spouse
- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 1. Low EE dyad: Positive interaction pattern.
HEE ST01
10
60
50
40
30
20
10
-10 Patient
- 20 Spouse
- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140
60
50
40
30
20
10
-10 ---Patient
- 20 ---Spouse
- 30 Change
0 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 3. High EE dayd: Asymmetric interaction pattern.
HEE GRA2
10
60
50
40
30
20
10
-10 Patient
- 20 Spouse
30 Change
- ~---.--.---.---.---.---.---r---r-~~~---.---.--~~~
o 10 20 30 40 50 60 10 80 90 100 110 120 130 140
Fig. 4. High EE dyad: Neutral interaction pattern.
The Marriages and Interaction Patterns 93
Table 3. Relationship Between EE and Interaction Pattern
Interaction pattern
Neutral, negative,
EE Positive or asymmetric Total
Low 9(30.0%) 3(10.0%) 12
High 5(16.7%) 13(43.3%) 18
Total: 14 16 30
x = 6.5 (P < 0.01)
Percentage agreement = 73.3%
References
Beck, A. T., Ward, C. H., Mendelsohn, M., H., and Doane, J. A. (1984). Interactional cor-
Mock, J., and Erbaugh, J. (1961). An invento- relates of expressed emotion in the families of
ry for measuring depression. Archives of Gen- schizophrenics. British Journal of Psychiatry,
eral Psychiatry, 4, 561-571. 144,482-487.
Berkowitz, R., Kuipers, L., Eberlein-Vries, R., Spanier, G. B. (1976). Measuring dyadic adjust-
and Leff, J. (1981). Lowering expressed emo- ment: New scales for assessing the quality of
tion in relatives of schizophrenics. In M. J. marriage and similar dyads. Journal of Mar-
Goldstein (Ed.), New developments in inter- riage and the Family 38,15-28.
ventions with families of schizophrenics. Lon- Spitzer, R. L., Endicott, J., and Robbins, E.
don: Jossey-Bass. (1978). Research Diagnostic Criteria for a se-
Brown, G. W., Birley, J. L. T., and Wing, J. K. lected group of functional disorders. New
(1972). Influence of family life on the course of York: Biometric Research Unit, New York
schizophrenic disorders: A replication. British State Psychiatric Institute.
Journal of Psychiatry, 121,241-258. Strodtbeck, F. L. (1951). Husband wife interac-
Hahlweg, K., Reisner, L., Kohli, G., Vollmer, tion over revealed differences. American
M., Schindler, L., and Revenstorf, D. (1984). Sociological Review, 16,468-473.
Development and validity of a new system to Valone, K., Norton, J. P., Goldstein, M. J., and
analyse interpersonal communication (KPI: Doane, J. A. (1983). Parental expressed emo-
Kategoriensystem fUr partnerschaftliche Inter- tion and affective style in an adolescent sample
aktion). In K. Hahlweg and N. S. Jacobson at risk for schizophrenia spectrum disorders.
(Eds.), Marital interaction: Analysis and mo- Journal of Abnormal Psychology, 92 (4),
dification. New York: Guilford. 399-407.
Hooley, J. M. (1984). Criticism and depression. Vaughn, C. E., and Leff, J. P. (1976). The in-
Unpublished D. Phil. thesis, University of Ox- fluence of family and social factors on the
ford. course of psychiatric illness. British Journal of
Kuipers, L., Sturgeon, D., Berkowitz, R., and Psychiatry, 129, 125 -137.
Leff, J. (1983). Characteristics of expressed Wing, J. K., Cooper, J. E., and Sartorius, N.
emotion: Its relationship to speech and looking (1974). The description of psychiatric symp-
in schizophrenic patients and their relatives. toms: An introduction manual for the PSE and
British Journal of Clinical Psychology, 22 (4), cat ego system. London: Cambridge University
257-264. Press.
Miklowitz, D. J., Goldstein, M. J., Falloon, I. R.
8. Patterns of Emotional Response
in the Families of Schizophrenic Patients
C. E. Vaughn
Introduction
In Chap. 2, Hooley succinctly summarizes medication) and others did not. The origins
the history of expressed emotion (EE) re- of schizophrenia were assumed to be bio-
search and its principal findings to date. She logical; there was considerable scepticism
reviews the considerable body of evidence regarding some theorists' views of the fami-
which suggests that the EE index has pre- ly's role in the etiology of the illness. Never-
dictive validity where relapse patterns in theless, a series of anomalous findings early
schizophrenia are concerned and refers to on in the research suggested that influences
the content and concurrent validity studies from within the home might affect the
which offer further proof that EE is concep- course of a schizophrenic illness. One such
tually sound. However, she also acknowl- anomaly was the link between relapse and
edge the existence of unresolved questions type of living group; another was the fact
and issues raised by the EE investigations. that male patients apparently did well even
The intention of this chapter is to take up if unemployed as long as the mother went
some of these questions and issues and ex- out to work (Brown, Carstairs, and Top-
plore them in the light of unpublished data ping, 1958; Brown, 1959). Both anomalies
from relatives' interviews - rich sources of could be explained, the investigators rea-
information concerning patterns of emo- soned, if patients were reacting to close ties
tional response and family interaction in the because of a sensitivity related to the dis-
months preceding a psychiatric admission. ease process. Theories of sensory overload
The material to be presented suggests some and emotional overarousal in schizophrenia
directions for further research and tentative perhaps were relevant. It therefore seemed
guidelines for clinical interventions in the appropriate to try to identify aspects of fam-
future. ily life which might contribute to a better or
A recurrent criticism of the EE research worse psychiatric outcome. There was no
is that it has failed to indicate precisely what suggestion that the qualities or characteris-
the concept measures, how it manifests it- tics to be identified were necessarily deviant
self, or how it operates to influence the vul- or that they were unique to the relatives of
nerable individual. While it appears to tap schizophrenic patients. This important
qualities of family life which can either pro- point is emphasized by Brown (1985) in a
tect patients against relapse or make relapse recent account of the path to the "discov-
more likely by the exacerbations of symp- ery" of EE. He recalls:
toms, the process by which this happens has
remained unclear. It seemed important that the occasional presence
Hints as to what might be going on ap- of deeply disturbed or unusual relationships be-
tween parent and patient should not be allowed
peared in the early epidemiological studies
to dominate our thinking. If I had any hunch
of schizophrenia conducted by Brown and about what was going on, it was that it involved
his group. This work began as a search for something a good deal less fundamental, indeed
environmental explanations of why some everyday. Therefore one way forward would be
patients relapsed after discharge (despite to develop an instrument capable of recording
the protection afforded by antipsychotic the range of feelings and emotions to be found in
98 C. E. Vaughn
ordinary families. Indeed, the family instrument behavior occurred and how they coped at
used to record "expressed emotion" was not de- the time. During the course of the interview
veloped with the families of schizophrenic pa- the focus shifts from symptom behaviors to
tients and it did not occur to me that there was more general patterns of family interaction,
anything amiss in this. such as the occurrence of irritability and
Brown and his colleagues' initial attempts quarreling and the amount and intensity of
to identify features in the home environ- contact between the patient and other fam-
ment predictive of relapse produced hun- ily members. There are specific questions
dreds of rating scales concerning different too about the quality of the relationship be-
aspects of family life. Of all these scales, tween patient and relative: Can you get
only three showed independent relation- close to him? Have your feelings for him
ships with the course of schizophrenia: changed since the trouble came on? Addi-
relative's critical comments, hostility, and tional questions concern the impact of the
emotional overinvolvement. These three illness: What difference has this hospitaliza-
scales together comprise the index of EE, tion made to you and the family? What has
which essentially is an indicator of a rela- been the most disturbing aspect of the trou-
tive's negative affect or intrusive overcon- ble for you? Although the interviewing pro-
cern toward the patient. Two additional EE cedure is governed by rigorous guidelines,
scales, warmth and positive remarks, are the approach is a flexible one and the tone
measures of positive affect which undoubt- that of an informal conversation rather than
edly contribute to the emotional atmos- an interrogation. The result almost always
phere in the home. They were not included is a rich picture of family life during the pre-
in the EE index, however, because oftheir admission period. The quality of informa-
complex interrelationships with the other tion obtained in most instances provides
EE scales and with relapse. For example, quite a good idea of relatives' characteristic
high warmth toward the patient is associa- responses in a time of crisis and their re-
ted with a good outcome only when the rel- ported impact on the patient, as well as
atives score low on emotional overinvolve- more general patterns of family interaction.
ment (EOI). Where high warmth is found While EE researchers generally have ac-
in combination with high EOI, relapse is cepted relatives' accounts as valid, until re-
very likely. cently the assumption of veracity was based
The EE index is rated on the basis of both primarily on the usefulness of the EE index
feelings expressed during the inverview and as a predictor of symptomatic relapse. An
reported behavior outside it. The Camber- element of doubt lingered: in the absence of
well Family Interview (CFI) was designed more direct evidence, one could not be sure
to elicit two kinds of information: objective that a relative's interview behavior or re-
information concerning life in the house- ported reactions necessarily reflected what
hold in the months leading up to the pa- went on in the patient's presence. How-
tient's admission and subjective information ever, recent independent investigations of
concerning the relative's attitudes and feel- direct interactions between patient and rel-
ings toward the patient and the illness. ative have confirmed the impressions glean-
Brown believed that if the relative were ed from relatives' interviews, suggesting
asked in a neutral fashion about quite spe- that in a majority of cases there is a corres-
cific details of the illness and related events, pondence between these different sources
information about feelings would naturally of information (Miklowitz, Goldstein, Fal-
follow. A number of different interviewing loon, and Doane, 1984). Reassured by this
techniques help to ensure that this happens. knowledge, let us now consider some of the
Questions about the occurrence of patient ways in which low EE and high EE house-
behaviors cover many different aspects of a holds differ. The discussion of qualitative
particular behavior: onset, severity, fre- data which follows is based on interviews
quency, social contact, reactions of every- with several hundred relatives of patients in
one who witnessed the behavior. Relatives England, America, and Australia.
are asked to give examples of the last time a
Patterns of Emotional Response 99
EE as an Indicator of the Pre-illness Relationship
A detailed analysis of the interview data for when stressed, however, frequently found
78 relatives in the 1976 Vaughn and Leff the strain of coping with someone who was
study established a link between the con- psychiatrically ill intolerable. Feelings of
tent of relatives' criticism and the quality frustration and helplessness commonly re-
of the pre-illness relationship, for both schi- sulted in expressions of anger toward the
zophrenic and depressed samples of pa- patient. However, these relatives' criti-
tients (Leff and Vaughn, 1985). For this cisms invariably were directed at specific
analysis, a distinction was made between symptom behaviors for which the patient
critical remarks concerning symptom was not held responsible.
behaviors which first appeared in the con- Where there appeared to be a poor rela-
text of an illness episode (for example, de- tionship between patient and relative prior
lusional behaviors, changes in levels of ac- to the onset of the illness episode, critical
tivity or irritability) and critical remarks remarks were almost exclusively about
about more general, enduring personality long-standing behaviors. For both the schiz-
traits of the patient. Results revealed that ophrenic and depressed groups, approxi-
for both diagnostic groups a major deter- mately 70% of all critical remarks fell into
minant of a relative's current response to this category. Criticism tended to center on
the patient and the illness was the way in aspects of the relationship with which the
which patient and relative got along before relative was markedly dissatisfied, partic-
the present illness episode. ularly communication and the amount of af-
If the pre-illness relationship was good, fection and interest shown by the patient.
the relative at interview tended to either The relatives concerned did not identify
make no critical remarks or to confine criti- these behaviors as manifestations of illness,
cism to comments about florid symptom but considered them to be integral charac-
behaviors. A critical response seemed to teristics of the patient's personality.
depend less on the degree of the patient's Thus, it seems that the kind of remarks
disturbance than on the relative's own per- made by a relative at a crisis point (time of
sonality. Relatives who described them- admission) can provide important clues as
selves as generally tolerant and easygoing to how patient and relative get along in nor-
persons tended to be noncritical. Those mal circumstances.
who admitted to being tense or moody
Determinants of EE
At a given point in time, determinants of ployment; and cross-cultural differences in
the relative's degree of EE are likely to in- societal responses to the illness. The last of
clude the patient's behavior (degree of these factors is discussed by Jenkins et aI.,
disturbance and extent of secondary handi- in Chap. 3. With the exception of the pa-
cap); the relative's perceived ability to cope tient's behavior, none of these influences
and related problem-solving skills; idiosyn- on EE has been studied in a systematic fas-
cratic personality factors; the amount and hion, but relatives' accounts suggest that
quality of information available concerning each is of some importance and warrants
the illness; external stresses such as unem- further investigation.
References
Brown, G. W. (1959). Experiences of discharged I. R. H. (1983). Premorbid and symptomatic
chronic schizophrenic mental hospital patients characteristics of schizophrenics from families
in various types of living group. Millbank Me- with high and low levels of expressed emotion.
morial Fund Quarterly, 37, 105 - 13l. Journal of Abnormal Psychology, 92,359- 367.
Brown, G. W. (1985). The discovery of "ex- Miklowitz, D. J., Goldstein, M. J., Falloon, I. R.
pressed emotion": Induction or deduction? In H., and Doane, J. A. (1984). Interactional cor-
J. Leff and C. Vaughn (Eds.), Expressed emo- relates of expressed emotion in the families of
tion in families: Its significance for mental ill- schizophrenics. British Journal of Psychiatry,
ness. New York: Guilford. 144,482-487.
Brown, G. W., Birley, J. L. T., and Wing, J. K. Vaughn, C. E., and Leff, J. P. (1976). The in-
(1972). Influence of family life on the course of fluence of family and social factors on the
schizophrenic disorders: A replication. British course of psychiatric illness: A comparison of
Journal of Psychiatry, 121, 241-258. schizophrenic and depressed neurotic patients.
Brown, G. W., Carstairs, G. M., and Topping, British Journal of Psychiatry, 129, 125-137.
G. G. (1958). The post-hospital adjustment of Vaughn, C. E., Snyder, K. S., Jones, S., Free-
chronic mental patients. Lancet, 2, 685-689. man, W. B., and Falloon, I. R. H. (1984).
Leff, J. P., and Vaughn, C. E. (1985). Expressed Family factors in schizophrenic relapse: Replic-
emotion in families: Its significance for mental ation in California of British research on ex-
illness. New York: Guilford. pressed emotion. Archives of General Psychi-
Miklowitz, D. J., Goldstein, M. J., and Falloon, atry, 41,1169-1177.
B. Modification of the Course of Schizophrenia
by Family Interventions
9. Working with Families of Acute Psychotics:
Problems for Research and Reconsideration
L. C. Wynne
References
Anderson, C. M., Hogarty, G. E., and Reiss, D. ington, D. C.: American Psychiatric Associa-
J. (1980). Family treatment of adult schizo- tion.
phrenic patients: A psychoeducational ap- Fox, H. A. (1981). The DSM-II1 concept of schi-
proach. Schizophrenia Bulletin 6: 290-505. zophrenia. British Journal of Psychiatry 138:
Brockington, I. F., Kendell, R. E., and Left, J. 60-63.
P. (1978). Definitions of schizophrenia: Con- Helzer, J. E., Brockington, I. F., and Kendell,
cordance and prediction of outcome. Psycho- R. E. (1981). Predictive validity of DSM-II1
logical Medicine 8: 387-398. and Feighner definitions of schizophrenia: A
Carpenter, W. T., McGlashan, T. H., and comparison with research diagnostic criteria
Strauss, J. S. (1977). The treatment of acute and CATEGO. Archives of General Psychia-
schizophrenia without drugs: An investigation try 38: 791-797.
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nal of Psychiatry 134: 14-20. clinical and genetic investigation. Acta Psychi-
Carpenter, W. T., and Strauss, J. S. (1974). atrica Scandinavica, Supplement 259: 13-133.
Cross-cultural evaluation of Schneider's first- Perlmutter, R. A. (1983). Family involvement in
rank symptoms of schizophrenia: A report psychiatric emergencies. Hospital and Com-
from the International Pilot Study of Schizo- munity Psychiatry 34: 255-257.
phrenia. American Journal of Psychiatry 131: Scott, R. D. (1976). Closure in family relation-
682-687. ships and the first official diagnosis. In J. J(Ilr-
DSM-II1. (1980). Diagnostic and Statistical stad and E. Ugelstad (Eds.), Schizophrenia 75,
Manual of mental disorders (3rd ed.). Wash- pp. 265-281. Oslo: Universitetsforlaget.
Working with Families of Acute Psychotics 115
Strauss, J. S., and Carpenter, W. T. (1974). The Archives of General Psychiatry 39: 778-783.
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Vaillant, G. E. (1964). An historical review of (1974). The measurement and classification of
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Vaughn, C. E., and Leff, J. P. (1976). The in- Wynne, L. C. (1983). A phase-oriented approach
fluence of family and social factors on the to treatment with schizophrenics and their
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10. Family Education as a Component
of Extended Family-Oriented Treatment
Programs for Schizophrenia
L. J. Cozolino and 1\1. J. Goldstein
Introduction
The desire for knowledge in relatives of beginning to evaluate family education, it
schizophrenic patients has stimuled the de- seems appropriate to start with such pro-
velopment of long-term intervention pro- grams because of the wealth of information
grams which include an initial phase of fam- that is available from the broader research
ily education. The present paper reviews project. This context allows us to have an
four family intervention programs designed accurate understanding of the information
for these relatives, which were summarized made available and the type of information
in a recent volume (Goldstein, 1981). These and treatment received by the patient and
programs were developed in the context of provides an opportunity for direct assess-
clinical research studies headed by Falloon ment of the interpretation and utilization of
and Liberman in Los Angeles, Leff and his information and practical management ad-
associates in England, and Anderson and vice.
Hogarty in Pittsburgh. Each program con- While all of these programs attempt to
tains a component specifically designed to delineate a family education phase from a
transmit some basic information about schi- long-term intervention phase, it is impor-
zophrenia and to answer questions concern- tant to note that long-term interventions
ing diagnosis, etiology, prognosis, and the have the opportunity to continue the edu-
relatives' role in the recovery process. cational process throughout the treatment
Family and patient education programs periods which range from 9 weeks with a 3-
did not begin with these newer family inter- month follow-up (Snyder and Liberman,
vention programs but have been developed 1981) to 2 years (Falloon, Boyd, McGill,
during the last 20 years throughout the Uni- Strang, and Moss, 1981). Thus, it is some-
ted States, Canada, and England in both what arbitrary to delineate an "educational
medical and community settings. They have component" in isolation from the rest of the
grown with the support of physicians, thera- program. In all of these programs, the edu-
pists, community workers, and family mem- cational component can be interpreted as a
bers to serve the needs of relatives and to seeding process or as an opportunity to be-
explore ways of getting information and gin with a common language and set of as-
support to a wide audience. Information is sumptions rather than expecting to transmit
delivered in many forms, ranging from information which will be understood and
books, pamphlets, and daylong courses to used by itself. In subsequent group meet-
being transmitted as part of ongoing family ings, Berkowitz, Kuipers, Eberlein-Fries,
therapy programs or mutual support or- and Leff (1981) found that although many
ganizations. The family education pro- participants seemed to need to hear the in-
grams analyzed in this paper have drawn formation given during the educational
heavily on this prior work. component a number of times, it did seem
The four family education programs out- " ... to have served the purpose ... of help-
lined in this paper are part of long-term ing relatives formulate questions that they
family intervention programs established may not have been able to ask before."
for research purposes in medical settings. In (p. 38). All program descriptions stress the
118 L. J. Cozolino and M. J. Goldstein
importance of exercising a great deal of ficacious methods of transmitting informa-
flexibility in both the educational and long- tion to the families has yet to be done. It is
term intervention phases because of the hoped that this comparison will serve as a
individual needs of particular families. starting point in the delineation of research
Because this is a relatively new move- questions to be addressed in the future de-
ment, systematic assessment of the most ef- velopment of family education programs.
Similar to the Liberman and Snyder pro- Two initial home sessions comprise the
gram in theoretical assumptions, Anderson family education component of treatment
et al. base their model on research in which take place with the patient present.
arousal/attention dysfunction and deviant Interaction and sharing are encouraged be-
family communication as well as on re- tween the patient and their family. Thera-
search on EE. pists often return to education later during
Anderson et al. introduce certain social therapy as the need arises.
work concepts, stressing a period of con- Family education and therapy are con-
necting with the family, which the other ducted in the home, which increases atten-
programs do not emphasize. Anderson dance and is thought to improve the gener-
et al. also refer to their daylong educational alizability of behavioral interventions. The-
component as a survival skills workshop for rapists are on 24-h call.
relatives, which underscores their emphasis This program is the most behaviorally
on pragmatic, day-to-day issues of coping oriented program reviewed here. Assess-
and management. Their overall goal is to ment begins with a behavioral analysis of
increase the predictability and stability of each individual and then of the family
the home environment, to increase adher- group. The interviewer attempts, through
ence to medication, and to provide support this process, to define a number of core
for the family, as well as the patient, communication and problem-solving defi-
through the recovery process. cits which become the focus of the com-
Like the Berkowitz et al. project, there is munication and problem-solving training.
a strong emphasis on the use of support Consistent with behavioral theory, assess-
groups and on the expansion of the family ment is carried on throughout the process,
and the patient's social support network. and the specific behavioral interventions
Their interventions focus on present prob- can be subsequently modified to meet new
lems during family therapy, postponing or changing needs.
long-term issues until after the immediate The Falloon et al. program is perhaps the
crisis of the schizophrenic episode is resolv- most extensive of all the approaches in
ed. While family therapy in this program terms of actual family involvement and
does not appear to be explicitly behavioral length of treatment, with 40 family sessions
in orientation, it does seem to be pragmatic being held over a 2-year period. Sessions
and problem focused. Communication are conducted in the home for the first 9
skills and problem-solving skills are pre- months and are either continued through
sented in a less structured manner than in the next 15 months or the family has the
the more behaviorally oriented programs. option of participating in community-based
family groups. Monthly medication evalua-
tions are conducted with the patient.
in the Falloon et al. program (Falloon, Participation of the patient at this point may
Boyd, McGill, Strang, and Moss, 1981). not be fortuitous, and family members may
The programs do differ in one important need an opportunity to consider matters in
factor and that is whether the patient is pre- a less emotionally charged context. In the
sent or not at these educational settings. In Falloon project, the patient has been dis-
two of the programs they are and in two charged and stabilized on medication for
they are not. One ofthe key issues for future 4-6 weeks before family education is car-
investigation is whether this particular com- ried out in the home with only the patient
ponent of a family program is inhibited or and significant relatives present. Is it the
facilitated by patient participation. This is level of remission, the home context, or the
not as simple an issue to resolve as it might focus on the single family unit that deter-
seem as the programs outlined in Table 1 mines the patient's participation? Some of
vary considerably in important parameters the projects use a group format while
which would affect the value of patient par- others, such as Leff et al. and Falloon et aI.,
ticipation. For example, the Anderson meet with an individual family unit. In
et al. family education program (survival what way do these contextual factors affect
skills) begins shortly after the patient is ad- the impact of a family education unit, if at
mitted to the hospital and still very psychotic. all? Further research is needed to clarify
Family Education as a Component of Treatment 121
whether the timing, group composition, or tape. An issue not clarified in Table 1 is that
site (home vs clinic) affect the impact of a in each of the treatment programs the fami-
family education program. ly education program was delivered, in
Note that those programs that involve part, by one of the persons who was involv-
relatives only do not appear to provide sep- ed in the longer term family program. Thus,
arate education for the patient. It remains it was not simply a case of a mental health
to be demonstrated whether separate pro- professional imparting information and
grams targeted specifically toward patients withdrawing from future contact from the
will enhance the impact of the programs family. Any future research on the impact
directed at the relatives. of these family education programs needs
To date, none of these family education to consider not only the issue of live vs
units have been prepared for mass media videotape format, but whether the person
distribution to be utilized in other settings. or persons who provide the information are
Clearly this represents a distinct possibility likely to be involved in the subsequent sup-
as there has been sufficient experience with port provided to the families who receive
the administration of these programs that the family education.
scripts could be created and put on video-
Besides attempting to "normalize" their ex- Falloon et al. (1980) Liberman et al. (1979)
perience to some degree, information Symptoms Symptoms
about diagnosis allows relatives to be better Disturbances of Thought broad-
thinking casting
able to communicate with professionals
Delusions Thought with-
they may encounter both in and outside of drawal
the program. Perhaps the biggest initial ob- Hallucinations Thought insertion
stacle in explaining the diagnosis of schizo- Incoherent talk Paranoid
phrenia is overcoming preconceptions delusions
based on movies and news reports and to Inappropriate Social with-
allay the fears of the patient and their fami- feelings drawal
lies based upon these misconceptions: Bizarre habits Work behavior
Self-care
· .. Schizophrenia means a disintegration of the Feelings
personality where a person finds it difficult decid- (flat affect)
ing what is real and what is not real. It is a little Thoughts
like having dreams when you are wide awake ... Conversation
We describe schizophrenia as a major mental ill- and speech
ness because it has a great effect on nearly every
aspect of a person's life. Everything that is im- While Leff and his group describe the above
portant in our lives may be affected by schizo- symptoms, their descriptions are less pa-
phrenia. The symptoms of schizophrenia are not tient centered and more focused on the in-
identical for every person, but they nearly always teraction between the patient and their rel-
produce a handicap in many aspects of everyday atives, as seen in the following excerpt:
living. (Taken from "What is Schizophrenia", Schizophrenia can also affect feelings .. . You
Falloon, McGill, and Boyd, 1980). may have noticed that he doesn't seem to care for
· .. a person suffering from schizophrenia has a you as he did before, or show his love for you in
different experience of reality than other people. the same way. There may be fewer and fewer
This means that the person with schizophrenia times when you can really talk to each other, and
sometimes relates to persons and events in a man- you may sometimes wonder whether he still feels
ner that is different enough from what most anything for you at all. He can't help this, be-
people usually expect that it can be said that the cause his usual feelings have been swamped by
schizophrenic has a split with reality. (Liberman the illness and he has become very wrapped up in
et al. 1979). himself.
Family Education as a Component of Treatment 123
Leff also describes: tions to the person with schizophrenia - is crucial
in the development and outcome of schizophre-
1. Instability of mood where the patient is at
times "miserable or desperate" and others nia.
when he is "very excitable and overactive" Thus, an important task of the information-
2. Social isolation al content is to shift focus from past fears
3. Reduced energy and blaming to a realistic and positive view
4. Apathy for the recovery process, involvement in the
5. Personal hygiene issues
program, and maintenance of the well-
Some of the programs go into an explora-
being of all family members.
tion of the phenomenology of a schizophre-
The problem of how to handle theories
nic psychosis. In the Hogarty/Anderson
concerning genetic factors is frequently ad-
survival skills workshop, excerpts of first-
dressed by developers of family education
person report of the inner experience of a
programs. The Liberman handout states,
psychotic break are read aloud and hand-
"Many people want to know if schizophre-
outs of such accounts are also provided to
nia comes from parents, they want to know
relatives. In the Falloon sessions, which are
carried out in the home with the patient pre- if they have to worry that someone else in
sent, both patient and relatives are asked to the family will get it. The heredity of schizo-
share their experience of the psychotic bre- phrenia is a complicated business, but it is
akdown. In both instances, it is reported clear that it sometimes runs in families and
that relatives report more sympathetic atti- sometimes does not." In other programs,
tudes toward the patient after such a session the genetic data are dealt with more expli-
as they appreciate that their relative's expe- citly. Any presentation of genetic theories
riences and behavior are not as unique as is likely to stimulate considerable discussion
they formerly believed. of risk factors for other offspring as well as
revive family arguments concerning whose
side of the family passed on the "bad"
Etiology and Course genes. Therefore, it is a topic that is covered
Although the etiology and course of schizo- in most family education programs but
phrenia may be the aspect of the illness needs to be handled with great care and sen-
which is least understood, it is perhaps the sitivity.
most important for the attitudes and morale Similarly, with regard to the stress side of
of the relative. Counteracting guilt con- the stress-diathesis theories covered in
cerning the cause of the illness and balanc- these programs, theories concerning the
ing realistic expectations for the future with family etiology of schizophrenia are either
a sense of hope is an important component played down or presented as unproven.
of these programs. All four programs are Stress, particularly during the post-dis-
grounded in a diathesis stress model of charge, aftercare period, is presented as a
schizophrenia, and they describe the genet- trigger of relapse, and family conflict is
ic as well as the environmental factors identified as a particularly potent stressor
which may contribute to the development during that period. Since a number of the
of schizophrenia. To the question "What is family education units are part of more ex-
the cause of schizophrenia?" Liberman et tended aftercare programs targeted spe-
al. explain: cifically for high EE family units, the im-
It is probably a better idea to think of the causes portance of reducing criticism and emotion-
of schizophrenia rather than a single cause. And al overinvolvement is emphasized as a
it is also important to think of factors which can mechanism for reducing family stress.
make the symptoms and life functioning better or While hope must be maintained, realistic
worse in a person who already has schizophrenia. expectations must also be supported. "Pre-
Since medication can improve the symptoms of paration" for relapse may serve as a stress
schizophrenia, it is likely that brain chemistry
changes are part of the problem. On the other inoculation as well as a sensitizer to a wor-
hand since psychotherapies and behavior thera- sening of symptomatology before another
pies which focus on the patient's environment episode.
also produce therapeutic change, it is felt that the In the Leff et al. syllabus, the following is
environment ... especially other people's reac- stated:
124 L. J. Cozolino and M. J. Goldstein
Some people only have one attack of schizophre- substitute with the dopamine and sneak-in there.
nia; they recover from this and never have anoth- The effect is to tone down the strength of the mes-
er. Others, luckily only a small number, do not sage, not as much can get through. This whole
respond to treatment at all. However, most pa- process of being excited and distracted and too
tients although they recover from the attack are much coming in at one time. This is a chemical
likely to have other attacks. These may occur way of enhancing the ... toning down process in
within weeks of recovery, or may happen years the cell which is not working at the moment. It
later. During further attacks new kinds of odd helps the body tone down and get equilibrium
behavior can appear, but often the same pattern back. It's the tune up - we're playing a trick on
will repeat itself. the receptors with medication. That's all we're
Although all of the family education pro- doing.
grams present material about etiology, they A key issue that is still unresolved is what
vary greatly in the detail covered. For ex- relatives and/or patients retain from the in-
ample in the handout Some Plain Facts formation provided. In some instances, lit-
about Schizophrenia, distributed by the tle of a technical nature is retained; in other
Liberman group as part of the family educa- cases, a key concept is retained which is
tion program, the section on causes of schi- found helpful. Consider the following
zophrenia states, "It is clear that schizo- quote from one of the relatives described in
phrenia involves a chemical problem in the the preface of this book who was sharing
brain. This is a problem that the person is her experience of family education:
born with and it's no one's fault." Contrast What helped was when you explained what hap-
this brief explanation with the extensive pens when there is a chemical imbalance or what
presentations by Hogarty, which covers is it, a dopamine flow? What happens inside their
some brief facts of neuroanatomy, neutro- head, I always had the idea that he could control
transmitter theory, the dopamine hypo- his symptoms, but we found that day that they
thesis, and the relationship ofthis model to really cannot control it. It is something that you
a hyperarousal theory of cognitive dysfunc- have no control over. It helped a greal deal, it
tion on schizophrenia. Hogarty states: really did, to know that he had no grip over real-
What you see on the board are two things that ity.
look like a star fish ... this is my feeble attempt to Or as another parent stated:
represent a neuron ... a neuron doesn't look that The number one point is that it is a chemical im-
big, in your brain right now there are the better balance like sugar diabetes that can be treated
part of ten billion neurons, and they are tightly with medication. He (the lecturer) went on to ex-
packed in ... I'm going to tell you a little bit about plain how this chemical imbalance bombarded
how the neuron works ... The center of the neu- with stimuli on the receiving end of the synapse
ron is the cell body and those little branches that made all kinds of sounds and sights magni-
which come out are ... called dendrites, and this fied - so the medication would screen out the
is a very important part ofthe cell body, the axon, dopamine that was bombarding your senses and
these are the nerve fibers ... There are messages eliminated some of the frightening sounds or sce-
that go through the body ... These ten billion nes or colors and they were brought down to nor-
neurons are connected but they are not physically mal perception and became more realistic.
wired together .. , and the message travels
through a very complex process ... Neuroanato- Even when retention is not great, relatives
mists refer to the message coming in as the af- often express appreciation that mental
ferent, they are affecting the cell and this would health professionals share with them the
be efferent ... (the spaces between cell) are cal- latest knowledge in this field. It is the be-
led synapses. After a description of dopamine ginning of an alliance, a building process
transmission, Prof. Hogarty continued: My guess than can facilitate relatives' investment in
is that everyone in this room has a family member the longer and more demanding phases of a
that has been ill who is receiving some form of sustained aftercare treatment program.
medication which we call antipsychotic medica- Difference in detail are also evident with
tion or antischizophrenic medication. You may regard to information provided about prog-
hear them referred to as tranquilizers. It turns out
that they don't tranquilize people, they operate nosis. Some programs are extremely ex-
on this (dopamine transmission) process ... They plicit in providing figures about relapse po-
put back the chemical balance. Those molecules tential while others are more vague One
look like the dopamine and they take its place, advantage of providing explicit figures
they block the crevice ... They'll compete and about relapse is that they provide a natural
Family Education as a Component of Treatment 125
segue into material concerning the protec- Maintenance drug
tive value of antipsychotic medication, a therapy
point emphasized in all four programs. Relapses rates and
medication
Symptoms likely
Treatment to improve
Symptoms likely not
All four educational components divide to improve
their treatment emphasis between pharma- Reasons patients
cological and psychosocial interventions re- stop taking
flecting the synthesis between these two medication
orientations, which until recently have Getting the right
dose
often been seen in opposition. The goal of Role of the family
this information is to increase drug com- in sustaining drug
pliance and stress the importance of both therapy
chemical and environmental components of
the illness.
Falloon et al. summarize their sessions on
medication thusly:
Medication 1. Regular tablet taking is the mainstay of
The Leff program describes medication: treatment of schizophrenia.
2. Major tranquilizers are very effective
These play an important part in the treatment of medicine for the treatment of schizo-
schizophrenia. They help to stop the voices in the
patient's head, they make him less anxious and phrenia.
restless and help him to think more clearly. They 3. In low doses they also protect a person
protect him against stresses coming from his own from a relapse of symptoms.
experiences and his everyday life. The effects 4. Side effects are usually mild and can be
cannot always be seen straight away. Some pa- coped with.
tients are not given tablets but are put on injec- 5. Street drugs make schizophrenia worse.
tions. These have the same effect as tablets but For the Liberman and Falloon projects, the
can be given less often. two sessions of education are followed by
interactive problem solving and communi-
In contrast to this minimal explanation of cation skills training, the actual details of
medication, the Falloon and Liberman pro- which are not described during education.
grams offer in-depth explanations of the The Leff and Anderson educational com-
range of medication and the benefits and ponents, however, include advice as to
risks of drugs used to combat side effects. what the families can do to assist the patient
The Leff et al. syllabus contains a single and themselves during the recovery pro-
page of drug information, while the Fal- cess. Their advice centers around reduction
loon, McGill, and Boyd syllabus is ten of contact, lowering EE, gaining support
pages long. Some of the psychopharmacol- from other families, and taking care of
ogical material provided by these investiga- yourself (the relative).
tors is summarized below. From the Leff et al. syllabus:
Falloon Liberman
Biochemical theory of Types of drugs The best thing for your to do in this situation is
schizophrenia Neuroleptics firstly, not to spend so much time with him so that
Types of medication Mood stabilizers you don't get on each other's nerves. It is impor-
Benefits of medication Antidepressants tant that the patient leads as independent a life
Reduced relapse Stimulants as possible ... If you have to be together a lot of
rates Types of neuroleptics the time, the best thing to do is not to shout or cri-
Relapse worse and effects ticize or get too involved.
without medication Generic names
Dosages Trade names The Anderson et al. psychosocial treatment
Warning signals Equivalent doses emphasizes both patient management and
Side effects Who is likely to concern for the relatives. The topics em-
Drugs/alcohol improve phasized are as follows:
126 L. J. Cozolino and M. J. Goldstein
Management ward understanding the experience of the
Benign indifference illness and contain information focused on
Realistic expectations
Normalization of family life
the long recovery period.
"Setting limits" The differences in detail offered and
manner of presentation may, in some cases,
Concern For Self be more an artifact of the authors presenta-
It may be a long process tion in their syllabi than of actual differ-
Take care of yourself ences in their programs. A great deal of
Mutual support between families flexibility is necessary to accomodate the
Families asked to share their wide range of needs and interests of the
gains with other families new to the project
various families of which these syllabi are
Written suggestions as to how to
start a parent's group are handed out as well merely a general format for presentation.
as information about parent of adult Thus, a program with a very detailed sylla-
schizophrenic (PAS) groups bus may omit detailed information to an
upset or low functioning family, while an-
With these foci, the Anderson et al. family other program with little technical informa-
education session remains true to its title of tion offers the opportunity for relatives with
survival skills workshop. a greater need for detailed information to
Throughout the educational component, have their questions answered.
each program maintains its basic perspec- It would seem that assessing the needs
tive. While they are all balanced with a mix- and abilities of the participants and match-
ture of didactic and experiential materials, ing information to these needs is crucial. In
the Falloon and Liberman programs take a program development, it may be best to
more information-oriented stance, which is have the ability and facilities to use these
separated from the rest of the treatment various modes of offering information
program. The Leff and Anderson programs about schizophrenia so that a wide range of
on the other hand seem more directed to- needs could and would be met.
References
Anderson, C. M., Hogarty, G., and Reiss, D. J. and Moss, H. (1981). Family management
(1981). The psychoeducational family treat- training in the community care of schizophre-
ment of schizophrenia. In M. J. Goldstein nia. In M. J. Goldstein (Ed.), New develop-
(Ed.), New developments in interventions with ments in interventions with families of schizo-
families of schizophrenics (pp. 79-94). San phrenics (pp. 61-78). San Francisco: Jossey-
Francisco: Jossey-Bass. Bass.
Berkowitz, R., Kuipers, L., Eberlein-Fries, R., Goldstein, M. J. (Ed.) (1981). New develop-
and Leff, J. (1981). Lowering expressed emo- ments in interventions with families of schizo-
tion in relatives of schizophrenic. In M. J. phrenics. San Francisco: Jossey-Bass.
Goldstein (Ed.), New developments in inter- Liberman, R. P., Aitchison, R. A., and Falloon,
ventions with families of schizophrenics (pp. I. (1979). Family therapy in schizophrenia: Syl-
27-48). San Francisco: Jossey-Bass. labus for therapists. Unpublished Manuscript.
Falloon, I., McGill, c., and Boyd, J. (1980). Snyder, K., and Liberman, R. (1981). Family as-
Treatment of Schizophrenia - Part II: Medica- sesment and intervention with schizophrenics
tion. Unpublished Manuscript. at risk for relapse. In M. J. Goldstein (Ed.),
Falloon, I., McGill, c., and Boyd, J. (1980). New developments in interventions with famil-
What is schizophrenia? Unpublished Manu- ies of schizophrenics (pp. 49-60). San Fran-
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Falloon, I., Boyd, J. L., McGill, C., Strang, J.,
11. Pilot Study of the Impact of a
Family Education Program on Relatives
of Recent-Onset Schizophrenic Patients
L. J. Cozolino and K. Nuechterlein
Introduction
It is assumed that advances in the technolo- ponent analyses may allow program coor-
gy of family education gained from broad dinators to direct available resources in
psychosocial research programs with schi- ways which will benefit the most clients.
zophrenic patients and their relatives (this However, there may be a tendency to enth-
volume, Chap 10, Goldstein, 1981) will be usiastically adopt family education, ab-
adapted and utilized in a variety of settings. stracting it from broader intervention pro-
Hospitals, professional training centers, grams, without understanding that the fam-
community mental health centers as well as ily's experience of education may be very
relative and patient support groups all de- different when such material is presented as
sire new and more impactful ways of de- a self-contained unit. Thus, as the technol-
livering information to their members. Spe- ogy of family education develops in the con-
cific analysis ofthe educational components text of broader intervention programs, par-
of these long-term treatment programs may allel research focused on family response to
be especially important for programs in education in the absence of family therapy
hospitals or community settings which can will increase our knowledge of the effects of
offer family education but may not have the family education programs in different the-
resources to conduct a full-scale family the- rapeutic or support contexts.
rapy program. In theory, educational com-
Pilot Study
As a first approach to this and more general sessions near the beginning of the outpa-
issues of family education, ten relatives tient program within 1-2 months of hospi-
from six different families with a schizo- tal discharge. Family members met with
phrenic member were interviewed. All rel- two UCLA Aftercare Clinic staff members,
atives participated in a family education usually on 3 consecutive weeks. They were
program in the context of an extended indi- given information about schizophrenia,
vidual patient aftercare treatment program. medication, and family stress management
All schizophrenic patients in this sample and discussed particular problem areas they
were enrolled in the Developmental Pro- were experiencing. The information given
cess in Schizophrenic Relapse Project (P. I. , to these families was adapted by Nuechter-
Keith Nuechterlein, Ph.D.) of the UCLA lein and Snyder from the programs of the
Clinical Research Center for the Study of earlier Liberman and Snyder (1981) project
Schizophrenia. The patients were all young, and the ongoing Anderson, Hogarty, and
recent-onset cases who were relatively early Reiss (1981) program. The information in-
in their contact with the mental health sys- cluded the sections on symptoms, possible
tem. The patients received medication and causal factors, and medication from the
individual and group therapy, while the Liberman and Snyder outline and those on
families were given three family education management of stress and communication
130 L. J. Cozolino and K. Nuechterlein
from the Anderson et al. outline. The fami- fects of stress, symptoms, the family role in
ly components of these programs were de- rehabilitation, family causes, medication,
liberately excluded because one focus of the and prognosis. If content was remembered
project was a medication-controlled exa- in each area, the usefulness and their reac-
mination of familial, behavioral, and psy- tion (i.e., if they found the information
chophysiological predictors of the course of comforting or disturbing) were discussed.
schizophrenic disorders and their predictive Ratings of usefulness of information
interrelationships. Thus, the family educa- were done on 8-point Likert scales where 1
tion program was purposely not an intensive was most useful and 8 was not useful at all.
attempt to change levels of expressed emo- Families were also asked to state what in-
tion (EE) or other familial factors and can formation they would have liked to have re-
serve as an example of the presentation of ceived which they were not given. Overall
family education without family therapy. program ratings were taken as well as rat-
These relatives were generally the same ings of specific management tips they re-
age and level of education as samples taken membered being told. Interviews were con-
by Hatfield (1981), and none were partic- ducted in the home because it was felt that
ipating in mutual support family groups in home interviews would afford families
the community. Thus, these people were more freedom of expression than the hospi-
generally isolated from others who shared tal environment. Families were assured of
their difficulties and, as a result of the ge- confidentiality and told that no feedback
ography of Los Angeles, most lived a good would be given to the clinic staff except
distance from UCLA. after it was combined with data from other
A semistructured consumer satisfaction families. The interviewer (L.J.C.) was in-
interview was conducted at their homes by troduced to the family by a telephone call
the senior author. The interview form is from the family's case manager and describ-
presented in Appendix A. While the format ed as an independent researcher who had
was somewhat structured, open-ended que- the support of the aftercare program but
stions allowed families a wide range of re- was in no way part of the treatment pro-
sponse. Relatives were first asked about the gram. This was done due to our concern
information they possessed prior to the ses- that they would feel that negative feedback
sions, where they obtained this informa- might jeopardize their relative's treatment.
tion, and how they reacted to it. Focusing The interview was conducted an average of
on the content of the program, they were 8.2 months after the last family education
then asked if they remembered specific con- session with a range from 5 months to 1
tent in the areas of diagnosis, cause, the ef- year.
Preliminary Results
General Reactions beginning the interviews, listening to step-
by-step detailed accounts of their relative's
While there were numerous suggestions for decompensation, their search for assist-
improvement, there was also consistent ance, or, more often, a description of some
praise for the program. Most felt that they current difficulty. Relatives also used us as
had finally found an ally after terrifying and a resource, asking for books, telephone
frustrating experiences with police, hospital numbers of family organizations, and refer-
staff members, and doctors. While the in- rals for therapists.
terview was fairly structured, relatives took Five of ten subjects remembered being
over for the most part and seemed to have a given practical tips, such as calling the
strong need to describe the details of their emergency number for assistance in a crisis,
family's difficulties. The interview had a reducing contact, and not pressuring the pa-
cathartic function for many as they vented tient. Of all the information remembered,
concerns and frustrations. We would often these tips were rated as the most useful. Of
have to wait between 15 and 30 min before the eight content areas, information con-
Pilot Study of the Impact of a Family Education Program 131
cerning medication was the most consist- I don't think it bothered us, we had already been
ently remembered and thought to be useful. bothered previously. (How?) When you go to the
hospital every day for a month and you see no
Relatives rated the data they were given change in your son - that bothers you ... so we
concerning cause and prognosis especially had already been bothered before. No it (the in-
unhelpful, describing it as too general and formation during the program) didn't bother us
vague. Especially in these areas, they felt at all.
that general information about schizophre-
nia was of little use as they went to the ses- On the other hand, some relatives who
sions expecting information specifically came expecting a rapid recovery period
about their ill relative. were distressed by the information that re-
It was found that the numerical ratings of covery would likely occur over a period of 1
relative usefulness had little meaning for year or 2. This raises an important issue
most of the categories beyond practical tips concerning the role of family education in
and medication because of the wide variab- fostering hope as well as instilling realistic
ility and the different mindsets with which expectations for the recovery process. A
the relatives were answering them (because delicate balance may need to be struck to
of this and in light of the small sample size at keep families actively and positively en-
the time of writing this report, statistical gaged in the treatment process. The impor-
evaluation has been omitted). Some rela- tance of maintaining this balance supports
tives took the stance that all of the informa- the notion of assessing the relative's expect-
tion was useful in contrast to total igno- ations prior to family education.
rance:
Anything is useful, you see, these questions are Did You Find the Information Pitched
really slanted from our context because - useful? at the Right Level for You?
Well God! Tell me anything - anything is useful.
I want to know! We have no backbone of infor- Another point of interest for us was wheth-
mation. er relatives found the information overly
technical, too elementary, or pitched at the
Others who really wanted extensive specific right level. None found it to be too techni-
information concerning their relative tend- cal, while those desiring more specific infor-
ed to rate all but the specific tips and infor- mation rated it as too elementary. While, in
mation on medication as too general to be general, relatives liked having the technical
useful: information about the possible role of neu-
We felt it was too general and a waste of time - it ral transmission abnormalities, "Its com-
got to the point where we didn't want to go back. forting to know that its something electri-
cal," their versions of what they were told
Was There Any Information Which You often caught us off guard:
Found Disturbing? Schizophrenia is like a tear in the brain - too
much chemical in the brain.
One goal of these interviews was to deter- There is a spot here (points to the center of the
mine whether any of the information dis- top of his head), she is missing this particular
turbed the family in any way. We thought thing and the medication can kind of work on that
that hearing the diagnosis of schizophrenia, area ... I can see that the medication has not
finding out about a prolonged recovery pe- made the gap any better.
riod, or hearing of the possible side effects And there are always the diehards even
of the medication might be particularly dis- after family education: "Schizophrenia is a
turbing during the family educational pro- split personality, isn't it?"
gram. In general, relatives reported that
they were so disturbed by their relative's
Did the Program Change the Way You Felt
behavior and the things they heard from po-
About Your Relative's Treatment?
lice and hospital staff prior to the educa-
tional program that they did not find the in- When asking relatives about the positive ef-
formation in the program to be particularly fects of family education, they found it diffi-
disturbing. One father stated: cult to separate the effects of the education
132 L. J. Cozolino and K. Nuechterlein
from the broader treatment program. Con- Would You Be Interested in Participating
cerning the sessions, one mother stated that in Relatives's Groups?
" ... they made me feel much more secure
None of these ten relatives were participat-
about the treatment. It also made me feel
ing in support groups, and only one expres-
that there was someone I could call." Thus,
the flesh and blood presence of a concerned sed even an interest in attending one ("but
professional seemed at least as important as only if it was close"). One said she was
the information. The information, while "anti-group" and another was quite upset
poorly remembered in many cases, repre- by the thought, saying:
sented a gesture of the establishing of a life- I don't want groups, I don't go for groups, I never
line, which was extremely positive. Rela- did go for groups, I don't want it ... I find that I'm
tives unanimously expressed their gratitude just not ready to go swap stories with other
and positive feelings toward the good inten- people. I don't feel that that is going to help me in
any way ... or just to know misery loves company
tions of the staff for offering their time. . .. NoWay!
None had ever been really given this sort of
attention before. A mother, when asked While previous research has addressed the
whether she found any of the information needs of members of relatives' groups,
comforting, keyed on the word comforting there is probably a still larger population of
and stated: relatives who have never participated in
Everything was a feeling of relief because we felt groups of any kind. It is interesting to con-
so isolated - once you get talking with other sider that the needs of these less social, less
people who deal with these problems and that interactive (if we can call them that) rela-
there was some place to tum for help - that's tives, may differ in significant ways from
what gave me relief - not so much the informa-
tion ... this program was a godsend.
those who will join groups and involve their
broader social network in the process of re-
Another mother was comforted by the fact covery. At the very least, it suggests that the
that other forms of treatment were explain- form of support and treatment that is view-
ed to her as well as the one offered by the ed as most desirables for families with schiz-
clinic. She said it made her feel as though ophrenic members may differ from one
she wasn't "up against an institution." population to the next.
Family Interview
Do you recall the session(s) at UCLA (or at your forting or' reassuring?
home) in which you were given information 10. Why do you feel that it was comforting or
about the causes and treatment of your relative's reassuring to you?
mental illness?
I would like to ask you some questions con-
cerning your experiences during these sessions. UCLA Sessions/General Impressions
This is not a test in any way! It is a consumer sur- 11. Generally, what do you recall being told
vey designed to find out whether or not these ses- about the nature of your relative's disorder
sions served your needs. All of this information is during the family education sessions?
confidential and will not be shared with clinic 12. Overall, did you find this information useful?
staff except after it is combined with responses Yes No
from others who have participated in the pro- 1..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
gram.
13. What information stands out in your mind as
Previous Knowledge being particularly useful in some fashion?
14. What kinds of information stand out in your
1. Before we discuss the sessions, I would like mind as not so useful?
to get an idea of how much you had learned 15. Overall, did the information you were given
about your relative's illness before you par- during the sessions seem to agree with your
ticipated in this program. How would you experience with your relative?
rate the amount of information you had Completely In large part About half
prior to these sessions? Somewhat Not at all
A Great Deal Nothing
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 16. In what ways did it seem to agree?
17. In what ways did it disagree?
2. What prior information did you find useful? 18. Overall, did the information tend to agree
3. What prior information did you find not so with the information you knew or believed
useful? prior to the sessions?
4. Where did you obtain this information? Completely In large part About half
Previous doctors _ _ Somewhat Not at all
Books _ _
Friends _ _ 19. What stands out in your mind in this regard?
Others __________________________ 20. Were any of the things you were told disturb-
5. Was any of the information you received be- ing to you?
fore you participated in the session(s) dis- 21. (If yes), what were they and how were they
turbing to you? disturbing?
6. (If yes), what information did you find dis- 22. Overall, do you feel the information was pit-
turbing? ched at the right level for you?
7. Why do you feel that it was disturbing to Too elementary Right Too technical
you? 1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
8. Was any of the information you received be-
fore you participated in the session(s) com- 23. What stands out in your mind as being too
forting or reassuring to you? elementary?
9. (If yes), what information did you find com- 24. What do you remember as being too tech-
142 Appendix A
nical? ing the causes of mental illness comforting or
25. What things do you remember that seemed reassuring?
just right? 46. (If yes), what did you find comforting and
26. As a result of the program do you feel that reassuring and why?
you have a greater or lesser understanding of 47. What weren't you told about the causes of
your relative's illness? mental illness that you would have liked to
Greater understanding Lesser understanding have been told?
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
27. Overall, what weren't you told about that Effects of Stress
you would have liked to have known?
48. Do you recall being told anything about the
effects that stress may have on mental ill-
Diagnosis ness?
28. Many sessions include a discussion of diagno- 49. What stands out in your mind in this regard?
sis, you know, words like schizophrenia, 50. How useful have you found this information
schizophreniform, psychotic reactions, or to be?
other mental disorders. Do you recall di- Useful Not useful
agnosis being discussed during your ses- 1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
sion(s)?
29. What stands out in your mind in this regard? 51. What information did you find most useful?
30. Do you find that this information is useful to 52. What information did you find to be not so
you? useful?
Useful Not useful 53. Did you find any of the information comfort-
1 ..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 ing or reassuring?
54. (If yes), how was it comforting and reassur-
31. In what ways do you find this information ing and why do you think that it had this ef-
useful? fect?
32. Are there ways in which you feel it is not use- 55. Did you find any of this information disturb-
ful? ing?
33. Was there anything in the discussion of di- 56. (If yes), how was it disturbing and why do
agnosis which you found comforting or re- you think that it was disturbing to you?
assuring? 57. What weren't you told about the effects of
34. (If yes), what did you find comforting or re- stress that you would have liked to have
assuring and why? known?
35. Was there anything in the discussion of di-
agnosis which you found disturbing?
36. (If yes), what did you find disturbing and
Symptoms
why?
37. Was there anything about diagnosis that you 58. Do you recall during the sessions discussing
would have liked to have been told that the various symptoms your relative may be
wasn't included in the sessions? experiencing?
59. What stands out in your mind in this regard?
Etiology 60. Did you find the information useful?
Useful Not useful
38. Often, the cause of mental illness are dis- 1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
cussed in these sessions, do you recall this
being discussed? 61. What did you find to be most useful?
39. What stands out in your mind in this regard? 62. What information was least useful?
40. Did you find this information useful? 63. Was any of the information concerning
Useful Not useful symptoms disturbing to you?
1 ..... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8 64. (If yes), what did you find disturbing and
why?
41. What information did you find most useful? 65. Was any of the information concerning
42. What information did you find least useful? symptoms comforting or reassuring to you?
43. Did you find any of the information concern- 66. (If yes), what did you find comforting and
ing the causes of mental illness disturbing? reassuring and why?
44. (If yes) , what did you find disturbing and why 67. Are there things which weren't discussed
do you feel it disturbed you? that you would have liked to know more
45. Did you find any of the information concern- about?
Appendix A 143
Family Role in Rehabilitation 89. Did you find this information useful?
Useful Not useful
68. Many sessions include advice to relatives as
1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
to how they can best help the patient during
the recovery process. Did your sessions con-
90. What do you recall as being useful?
tain any information in this area?
91. What do you recall as being not so useful?
69. What stands out in your mind in this area?
92. Do you recall being told about the possible
70. Have you found this information to be use-
side effects of the medication?
ful?
93. Did knowing about the possible side effects
Useful Not useful
help you keep your relative on medication?
1. .... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
94. Was there anything discussed concerning
medication which was disturbing to you?
71. What do you recall as being most useful?
95. (If yes), what did you find disturbing and why
72. What information seems to be least useful?
do you feel that it disturbed you?
73. Was any of this information comforting or
96. Was there anything discussed concerning
reassuring to you?
medication which was comforting or reas-
74. (If yes), what did you find comforting or re-
suring to you?
assuring and why do you feel that it had this
97. (If yes), what did you find comforting or re-
effect on you?
assuring and why do you feel that it was reas-
75. Was any of the information disturbing to
suring to you?
you? 98. What weren't you told about medication that
76. (If yes), what was disturbing and why do you
you would have liked to have known?
feel that it was disturbing to you?
77. Are there issues concerning the family's role
in rehabilitation that you would have liked to Prognosis/Recovery Period
discuss that were overlooked during the ses-
99. One session may have included advice con-
sions? cerning your relative's convalescence or
recovery period. What do you remember in
Family Etiology this regard?
100. Was this information useful?
78. Many times when a family member is stric- Useful Not useful
ken with a psychological illness, close relati- 1 ..... 2 ..... 3 ..... 4 ..... 5 ..... 6 ..... 7 ..... 8
ves may feel that they are in some way to
blame or that there may have been some- 101. Was this information comforting or reas-
thing that they could have done to prevent suring in any way?
the illness. Did you experience any of these 102. (If yes), what did you find comforting and
feelings when your relative became ill? reassuring and why?
79. What kinds of feelings did you have in this 103. How did you react to this information, was
regard? it disturbing to you in any way?
80. Was this discussed in the sessions at all? 104. (If yes), what did you find disturbing and
81. Was anything said that was disturbing to why?
you? 105. Was there any discussion concerning your
82. (If yes), what was disturbing to you and why? relative's future?
83. Was anything said that was reassuring or 106. What do you recall being discussed?
comforting to you? 107. How did you react to this information, was
84. (If yes), what was comforting and why do feel it disturbing to you in any way?
it was comforting to you? 108. (If yes), what did you find disturbing and
85. What do you remember being said about why?
these issues? 109. How useful did you find information con-
86. As a result of your attending the sessions, cerning your relative's future?
have your thoughts and/or feelings changed Useful Not useful
in regard to this issue? 1.. ... 2 ..... 3 .... .4 ..... 5 ..... 6 ..... 7 ..... 8
114. What things have you learned about how to Other Participants
deal with your relative's illness which might 120. Were there members from other families
be useful to other families? with you when you went through the pro-
115. Were there practical sorts of advice that you gram?
weren't given that you would have liked to 121. How many others were there?
have gotten?
Introduction
In recent years, several models of family dropping out after only a few visits. It has
treatment have been developed which at- become important, therefore, to develop
tempt to include an educational component treatment programs which would help fam-
as part of a larger program of intervention ilies to perform this caretaking role, pro-
for schizophrenic patients and their famil- grams which are not dependent solely upon
ies. These models can be generally classi- the motivation of patients.
fied as psychoeducational family therapies. Second, recent British studies of expres-
They aim to keep patients out of hospitals sed emotion (EE) have confirmed long held
and return them to productive life in the clinical impressions that families have an
community by teaching patients and famil- impact on the course of the patients' illness.
ies about the illness and its management, These studies demonstrate that measures of
treating the family as a resource rather than high EE in family members is correlated
as a stress, focusing on concrete problem with high relapse rates for patients. (Brown
solving and specific helping behaviors for and Birley, 1968; Brown, Birley, and Wing
coping with stress, and working in tandem 1972; Vaughn and Leff, 1976; Hooley,
with medication programs. These models Chap. 2). These findings have stimulated
emphasize the likelihood of a biological increased interest in attempting to develop
basis of the illness and the negative impact ways of modifying family systems to de-
of stress on patient ability to function. The crease family intensity and thus the likeli-
underlying assumption of the interventions hood of patient relapse.
used in psychoeducational models is that Third, the first controlled study which in-
giving families information about the na- cluded an attempt to provide patients and
ture of the illness, along with specific sug- families with some understanding of the ill-
gestions for coping with it effectively, can ness and ways to cope with had dramatic re-
decrease tIie intensity and conflict inherent sults. Michael Goldstein and his colleagues
in family life, and thus decrease the likeli- from UCLA (Goldstein, Rodnick, Evans,
hood that patients will relapse. May, and Steinberg, 1978) designed a 6-
There seem to be a number of reasons week program of family therapy in which,
why these models are attracting so much following hospitalization, patients were
attention today. First, major changes have randomly assigned within a 2x2 design:
occurred in patterns of mental health care high- or low-dose drug therapy, and family
for severely disturbed patients. Policies therapy or no therapy. The Goldstein
supporting deinstitutionalization have cau- model of family intervention was brief, con-
sed minimally functioning patients to be re- crete, and problem focused. The goals of
turned to the community after very brief the program were to identify the events that
hospitalizations. Consequently, families were stressful to the patient and then to pre-
have become long-term primary care agents vent the occurrence of these events or to
for very disturbed patients. Many of these mitigate their destructive impact. Family
patients do not cooperate with plans for af- sessions began by exploring the psychotic
tercare treatment, failing to attend at all or experience, with the therapist helping the
146 C. M. Anderson
patient and the family to discuss the illness family therapy and high doses of medica-
and its symptoms. Out of these discussions, tion. In other words, this intervention pro-
the therapist helped the family and patient gram achieved its primary goal of helping
to identify and agree on two to three specif- patients to maintain themselves in the com-
ic stresses that were of particular current munity during the high-risk period immedi-
concern. Conflicts with significant others or ately following hospitalization through the
other stresses, that are viewed as potential- provision of only six sessions of family ther-
ly precipitating a psychosis were emphasiz- apy. Although the differences between the
ed. Although symptoms themselves were groups were less dramatic at long-term fol-
often labeled as stressors, attempts were low-up points (Goldstein and Kopeikin,
made to focus on the interpersonal conse- 1981), the impact of this program was dra-
quences of symptoms rather than symptoms matic enough to inspire increased optimism
perse. regarding attempts to intervene with fami-
Following the identification of stressors, lies of schizophrenic patients.
the therapist helped families to develop This paper will describe the psychoedu-
strategies to avoid these stresses or methods cational model developed in Pittsburg as a
of coping with them when they occurred. part of a larger research project, which is
With the therapists guidance, the need for both attempting to replicate the British
both the family and the patient to accomo- work on EE and attempting to investigate
date to the other was emphasized. Once the impact of various strategies of interven-
coping strategies were developed, the ther- tion in the aftercare of patients with schizo-
apist helped the patient and the family to phrenia.! The larger research project
implement them. When necessary, coping screens patients to insure they meet Re-
skills were developed using direct teaching, search Diagnostic Criteria for schiz-
coaching, and practice. When problems ophrenia, rates the level of EE of their
arose in the implementation of these new family members, and randomly assigns
coping strategies, obstacles to the imple- patients with high EE families to one of four
mentation process were analyzed and the treatment cells: family therapy, social skills
strategies were modified. Finally, thera- training, family therapy and social skills
pists helped families and patients to antici- training, or medication alone. Patients and
pate and plan how they would handle future their families are followed in these treat-
stress. ment modalities for 2 years with various
The results of this short-term program measures of individual and family function-
were extremely positive. After 6 weeks of ing taken at periodic intervals. This paper
treatment, the low medication-no family will briefly note the assumptions and goals
therapy group had a relapse rate of 24% of the family program, describe its compo-
while the high medication-family therapy nents and stages, present some preliminary
group had no relapses at all. After 6 findings about its effectiveness alone and in
months, the relapse rate increased to 48% combination with social skills training, and
for the low dose-no family therapy group, discuss some of the common elements of
but remained at 0% or those receiving this and four similar programs.
Assumptions
It is assumed that whatever the "cause" of Tecce and Cole, 1976; Venables, 1964,
schizophrenia, patients with schizophrenia 1978). This patient vulnerability is probably
appear to have a "core psychological defi- exacerbated by the range of behaviors and
cit," which appears to increase their vul- emotions that their families are likely to dis-
nerability to internal and external stimuli
(Broen and Storms, 1966; Lang and Buss, 1 This research project, under the direction of
1965; Payne, Mattussek, and George, 1959; Gerard Hogarty, is partially funded by Grant No.
Rabin, George, Doneson, and Jentons, MH 30750 from the National Institute of Mental
1979; Shakow, 1962; Silverman, 1972; Health.
Psychoeducational Family Therapy 147
play. For instance, communication in fami- ture, and specific coping mechanisms of use
lies of schizophrenic patients often includes in dealing with a psychotic family member.
communicative behaviors that are vague, A highly structured and directive approach
unclear, amorphous, tangential, or lacking was used to increase the predictability and
in acknowledgment (Goldstein and Rod- stability of the family environment. An ed-
nick, 1975; Jacob, 1975; Jones, 1977; Jones ucational component was included to in-
et aI., 1977; Singer and Wynne, 1965,1966; crease family knowledge about the illness
Wynne, 1961). Whether or not these com- and confidence in coping with it, thus de-
munication patterns predate the illness or creasing family anxiety about the patient
contribute to its etiology, it would seem log- and their ability to react helpfully. The pro-
ical that patients who have problems con- gram has four basic overlapping phases,
trolling and processing stimuli would have separated here for the sake of clarity. Since
difficulties coping with these complicated the entire program is discussed in more de-
and confusing family communications. tail elsewhere (Anderson, Hogarty, and
Furthermore, when patients have be- Reiss, 1980), only the major points will be
come acutely psychotic, families usually re- stressed.
port feelings of anxiety, guilt, anger, and
sadness (Hatfield, 1978; Kreisman and Joy,
Phase I: Connecting with the Family
1974). These emotions are likely to increase
the intensity of family life, and, since the ill- Based on the assumption that no interven-
ness is a chronic one, this intensity is likely tion can succeed unless the family can hear
to increase over time as family members are or use it constructively, the first phase of
unable to find ways to help the patient. It treatment, which emphasizes the establish-
might be hypothesized that family members ment of an allliance with the family, begins
in such chronic crises would come to re- immediately after the patient's admission to
spond to patients in one of the two ways the hospital. Since all families begin the
Brown describes as components of high program during a serious crisis, and most
EE: becoming overinvolved, attempting to have had multiple unsuccessful contacts
constantly monitor and protect patients with other hospitals and professionals, spe-
from themselves or the environment, or be- cial attention is given to the creation of an
coming frustrated, angry, rejecting, and atmosphere which increases the family's re-
withdrawn from patients and treatment sys- ceptivity to treatment intervention. Phase I
tems. Either of these emotional responses interventions first involve joining the family
would appear to both decrease family abil- by eliciting their reactions to the patient's
ity to cope with patient behaviors and to be illness and to past attempts to cope with it,
problematic to a patient vulnerable to in- as well as eliciting their perceptions of their
tense stimuli. In summary then, these two own current needs and problems. Hope-
forces (the patients vulnerability and the fully, these discussions communicate to
turmoil of families) probably interact to the families that therapists care about what
patient's disadvantage in a spiraling man- they have been through, are not critical
ner; the patient's vulnerability to stimuli about how families have attempted to cope
causing symptoms which upset family mem- with patients, and genuinely want to know
bers, who in turn upset the patient, and so family ideas and views of what is helpful.
on. Once the family has begun to form a rela-
Because of this hypothesized relationship tionship with the therapist, the therapist is
between patient vulnerability and family established as the family's ombudsman or
anxiety or behaviors, this program of family representative in relationship to the hospi-
intervention was designed to accomplish tal system. Since the staff of inpatient facili-
two goals: (1) to decrease the patient's vul- ties are primarily involved with the patient
nerability to stimuli through a program of on a daily basis, it is easy for them to neglect
maintenance chemotherapy and (2) to de- families or fail to see family needs. The
crease the intensity of the family environ- creation of a family representative serves to
ment through a program of providing the balance this skewed perspective and pre-
family with support, information, struc- vent the alienation of families from the tre-
148 C. M. Anderson
atment team. Thus, the family ombudsman therapy, pharmacology, megavitamins,
keeps the family informed of ward decisions homeodialysis. Every attempt is made to
about the patient, ensures the input offam- discriminate between the facts, theory, and
ily concerns and needs into treatment plan- opinion about each ofthese issues. Because
ning, and provides the family with structure medication compliance is viewed .as a cru-
and concrete help in coping with the illness cial component of the program, the impor-
and the hospitalization. In this way, the the- tance of antipsychotic medication is given
rapist also begins to mobilize the family's special attention. Mechanisms of action,
concern and involvement into constructive possible negative side effects, and the use of
attempts to help themselves and the pa- antiparkinsonian agents are explained and
tient. By the end of the hospitalization statistics about the risk of relapse on and off
(which usually is less than 3-4 weeks), the medication are shared. In particular, the
family, patient, and therapist arrive at a tre- critical importance of family support for
atment contract which roughly specifies the and feedback about the medication pro-
goals, content, length, rules, and methods gram is stressed.
of the aftercare family program. This pro-
gram, then, continues for 1-2 years after
Information About Management
patient discharge from the hospital.
of the Illness
Following the presentation of general facts
Phase II: Survival Skills Workshop
and theories, families are introduced to a
Based on the assumption that people are series of techniques for managing patients.
more anxious about what they do not un- Based on the assumption that families can-
derstand, the survival skills workshop seeks not accept staff suggestion unless they
to provide the family with as much informa- genuinely believe that the staff know how
tion as possible about the nature of schizo- hard it has been to cope with this illness, this
phrenia. The education workshop was de- discussion begins with a description of what
signed as a multiple family enterprise to families have probably done over the years
simultaneously promote deisolation of the that has not worked.
family and desensitization about the subject Following this description, families are
of mental illness. It is a daylong event at- told that while there is no firm evidence that
tended by all the members of four or five families cause schizophrenia, there is rea-
families who are new to the program. (The son to believe that families have the power
patient does not attend.) Every attempt is to influence the course of the illness. They
made to encourage an informal atmosphere are helped to see the need to create barriers
in which families can question professionals to overstimulation of the patient by estab-
and interact with one another. The work- lishing firm, clear, and approximate bound-
shop is held as early in the treatment pro- aries. Families are encouraged to set limits
cess as possible because it also serves to on unacceptable behaviors, while allowing
establish the basic themes of the entire fam- patients to set their own pace toward recov-
ily program. The workshop focuses on the ery. This theme is translated into specific
following categories of information. suggestions for responding to the patient's
fears, delusions, paranoid thoughts, obses-
sive rituals, or threats of violence. Finally,
Information About the Illness
families are strongly encouraged to avoid
The most recent data about the phenome- centering their lives around patients. They
nology, onset, treatment, course, and out- are asked to attend to their own needs, the
come of schizophrenic disorders is present- needs of other family members, and to mo-
ed in clear, understandable language. bilize a social support network to maintain
Theories of etiology, ranging from genetic their own ability to cope and survive over
and biochemical to family and cultural, are time.
explained. What is known about the pro-
gnosis of the illness is also outlined, as are
various methods of treatment: psycho-
Psychoeducational Family Therapy 149
Phase DI: Reentry and Application their expectations of patients. Since pro-
of Workshop Themes gress on these issues is exceedingly slow, a
great deal of support is given to family
Highly structured low-key individual family members to enable them to tolerate inactiv-
sessions are held as soon as the acute phase ity, amotivation, and apathy.
of the illness has been controlled sufficient-
ly to enable the patient to attend. Once pa- Phase IV: Continued Treatment
tients have left the hospital, these sessions or Disengagement
occur once every 2-3 weeks. The interven-
tions of these sessions are based on the Once the goals for effective functioning
themes established in the survival skills have been attained (and these goals differ
workshop and relate largely to the reinfor- depending on the patient's abilities, the
cement of family boundaries and the gradu- length of impairment, and tolerance level of
al resumption of responsibility by the pa- families), the model calls for the family to
tient. be presented with two possible options for
Three kinds of boundaries are stressed on treatment: (1) more traditional family-
an ongoing basis. The interpersonal bound- oriented treatment to resolve long-term
aries between family members, the gener- family conflicts of unfinished business or (2)
ational boundaries between parents and periodic supportive maintenance sessions
offspring, and the family boundary with the of gradually decreasing frequency.
larger social community support system. The first three phases of this model of
The first two types of boundaries are rein- family intervention do not offer families the
forced, largely by encouraging families to opportunity to deal with family issues and
establish clear expectations, rules, and problems that do not immediately relate to
limit-setting processes. The third type of the patient's survival in the community. In
boundary, that between the family and the fact, the model specifically discourages the
community, is minimized by stressing the discussion of upsetting topics, such as mari-
family's need for the development of a tal discord, unresolved losses, or major
support system beyond the nuclear family. moves toward emancipation. Nevertheless,
Over time, patients are gradually en- some of these issues could interfere with the
couraged to assume more responsibility for ongoing growth and development of family
their lives and functioning. Initially, the en- members, and once the crisis has passed,
tire treatment focus is on the patient's sur- family members are offered the opportuni-
vival outside of the hospital. As signs of life ty to devote their energies to resolving
begin to occur in patients, the sessions gra- them. Unless it is thought that the issues
dually emphasize a return to effective work have direct and immediate impact on the
and social functioning. This is initially ac- patient's progress, families are to be offered
complished by the assignment of small hou- a choice about this phase of treatment since
sehold tasks or tasks which involve a mini- contracting to help the patient is. not
mal amount of socialization with outsiders. thought to give the right to unilaterally de-
Later, more ambitious tasks are assigned, termine the family's general goals or meth-
and families are encouraged to increase ods of attaining them.
Preliminary Results
Results for the 1st year of treatment using no patient in the treatment cell which re-
this model have been encouraging. Among ceived both family therapy and social skills
treatment takers (n = 88), 19% ofthose re- training experienced a relapse. In contrast,
ceiving family therapy alone experienced a nearly 36% of those receiving chemothera-
psychotic relapse in the year following hos- py and support relapsed. When all assigned
pital discharge. Twenty-one percent of patients were studied (n = 102), only a sig-
those receiving an individual behavioral nificant effect for family therapy could be
therapy (social skills training) relapsed, but identified in lowering relapse. Most impor-
150 C. M. Anderson
tant, when patients who were entirely faith- feel that investigators familiar with the EE
ful in adhering to their maintenance chemo- method and associated family therapists
therapy were included, a clear and signifi- (ourselves included) have succumbed to a
cant effect for family therapy was observed. profound error in judgment in limiting
Analyses regarding the adjustment of these these modern interventions to high EE pa-
patients are not complete as of this writing, tients and their families. High EE, it seems,
but in general, there is no evidence that has become the exclusive definition of high
family therapy or social skills training are risk in these studies. Admitting patients to
simply maintaining poorly adjusted patients studies who come from high EE houses por-
in the community just to make the relapse tends to place under observation essentially
rates "look good". If anything, clinical a group of unmarried males living in paren-
judgments regarding the "degree of illness" tal homes. In our own studies, this group
and "change in clinical state" pre- and post- represents but a subsample of the "at risk"
treatment reveal a significant effect for fam- schizophrenic population. Other samples,
ily therapy. (There is also a trend suggesting including married and unmarried females,
better role performance for social skills pa- are also at high risk for relapse, and we
tients as well.) Studies conducted at the believe these subgroups might also profit
University of Southern California by Fal- from these interventions.
loon's group (Chap. 14) and in London by We surmise from the results we have
Leff's group (Chap. 13) revealed that 6% achieved so far that the primary effect of
and 9% of family therapy-treated patients, family treatment is a prophylactic one and
respectively, experienced a relapse by 9 that these experimentally treated patients
months, but that 44% and 50% of controls are not simply being maintained in the com-
treated with drug and individual therapy munity in a more impaired condition. Al-
had relapsed by 9 months. Thus, there ap- though both family treatment and social
pears to be an increasingly broad validation skills training are useful, a limitation of the
of the effectiveness of family approaches, at social skills training approach seems to be
least in the forestalling of a psychotic re- its inability to engage or maintain patients
lapse. This, in turn, increases the potential who are actively psychotic at the time of
for helping the patients to be integrated discharge. The family approach, however,
within the communities. appears to buy time for patients, permitting
We do not, however, wish to be intem- them to more fully recover by decreasing
perate in our claims. The results, at least family distress, educating them about the
from our own study, have demonstrated illness, reducing their expectations and uni-
that these approaches forestall relapse but tary views of the illness, and otherwise in-
in no way provide "prevention" per se. To corporating new coping strategies. How-
date, relapse rates continue to rise as pa- ever, in facilities with long-term hospital-
tients near the end of their 2nd year of treat- izations or who otherwise discharge pa-
ment. An uncensured estimate of relapse tients in a more clinically stable condition,
into the 2nd year of treatment reveals that both family therapy and social skills trai-
25% of family therapy alone patients, 35% ning might well be effective interventions in
of social skills training alone patients, 22% significantly lowering schizophrenic re-
of the combined treatment patients, and lapse. The combined treatment approach
57% of drug-treated controls have ex- provides an additional and important pro-
perienced a relapse to date. Further, we phylactic advantage.
References
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Schizophrenia Bulletin, 6 (3), 490-505. and lifes change and the onset of schizophrenia.
Broen, W. E., and Storms, L. H. (1966). Lawful Journal of Health and Social Behavior, 9,
disorganization: The process underlying a schi- 203-214.
Psychoeducational Family Therapy 151
Brown, G. W., Birley, J. L. T., and Wing, J. H. Payne, R. W., Mattussek, P., and George, E. I.
(1972). The influence of family life on the (1959). An experimental study of schizophren-
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Goldstein, M., and Kopeikin, H. (1981). Short (1979). Studies of psychological functions in
and long term effects of combining drug and schizophrenia. In: Bellak, L., (ed.). Disorders
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May, P. R., and Steinberg, M. (1978). Drug Singer, M. T., and Wynne, L. C. (1965). Thought
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(5),355-359. search Reports, 20, 25-38.
Jacob, T. (1975). Family interaction in disturbed Tecce, J. J., and Cole, J. O. (1976). The distrac-
and normal families: A methodological and tion-arousal hypothesis, CNV and schizophre-
substantive review. Psychological Bulletin, 82, nia. In: D. I. Mostofsky (ed.). Behavior control
33-65. and modification of physiological activity. Eng-
Jones, J. E. (1977). Patterns of transactional style lewood Cliffs, NJ: Prentice-Hall.
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nics. Family Process, 16,327-337. fluence of family and social factors on the
Jones, J. E., Rodnick, E., Goldstein, M., course of psychiatric illness. British Journal of
McPherson, S., and West, K. (1977). Parental Psychiatry, 129, 125-137.
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Kreisman, D. E., and Joy, V. D. (1974). Family pp. 1-47). New York: Academic Press.
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Lang, P. J., and Buss, A. H. (1965). Psychologic- Press.
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tivation. Journal of Abnormal Psychology, 70, gnments and splits in exploratory family thera-
77-106. py. In N. Ackerman, F. Beatmen, S. Sherman
Leff, J., and Vaughn, C. (1980). The interaction (Eds.), Exploring the base for family therapy
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in schizophrenia and depressiv neurosis. Brit- sociation of America.
ish Journal of Psychiatry, 135, 146-153.
13. Controlled Trial of Social Intervention in the
Families of Schizophrenic Patients
J. Leff, L. Kuipers, R. Berkowitz, R. Eberlein-Vries, and D. Sturgeon
Introduction
A robust association has been established these results is reproduced here (Figure 1).
between the level of expressed emotion These issue of the direction of cause and ef-
(EE) shown by relatives and the outcome of fect in the relationship between relatives'
schizophrenia in patients living with them EE and patients' relapse has been ap-
(Brown, Monck, Carstairs, and Wing, proached by using statistical techniques to
1962; Brown, Birley, and Wing, 1972; define the role of possible mediating fac-
Vaughn and Leff, 1976a; Leff and Vaughn, tors, such as patient's disturbed behavior.
1981). Relapse of schizophrenia is more The possibility that such behavior might
likely if patients live with relatives who are lead both to high EE in relatives and to re-
excessively critical and/or overinvolved. lapse in the patients was eliminated by a
Such relatives are designated as high EE. variety of statistical approaches (Brown et
Two factors appeared to operate in a pro- aI., 1972; Vaughn and Leff, 1976a). How-
tective manner for patients living whith ever, a causal relationship between high EE
high EE relatives. These were regular and schizophrenic relapse and low EE and
maintenance therapy with neuroleptic patients remaining well can only be de-
drugs and the establishment of a social dis- monstrated convincingly by an experiment
tance between patient and relative, as mea- in which relatives's EE is manipulated and
sured by the amount of face-to-face contact patients' relapse rate is monitored. The
during a typical week. Furthermore, these same argument applies to the possible pro-
two factors seemed to be additive in their tective nature of low face-to-face contact,
protective effect. The evidence for these which can only be established beyond doubt
conclusions was derived from an analysis of by an experimental approach. This paper
pooled data from the two most recent stu- reports an experiment directed at both
dies (Brown et aI., 1972; Vaughn and Leff, these issues.
1976a). The relevant figure setting out
Method
and a staff member, however trivial, has
Design
therapeutic potential, even a standardized
The problems to be surmounted in design- assessment procedure. We recognize that
ing a controlled trial of any social therapy there is no ideal solution to all the inherent
have been explored in detail by Leff (1981). problems, but present our design as the op-
The double-blind placebo controlled drug timum under the circumstances.
trial is a sound basis to start from, but a We chose to study patients at highest risk
number of modifications are necessitated of relapse, represented by subgroup 6 in
by the nature of social treatments. For ex- Figure 1. Virtually all these patients not
ample, there is no placebo for a social treat- taking regular medication and living in high
ment. Any interaction between a patient contact with high EE relatives relapsed
154 J. Leff et al.
Subgroups
LowEEI3%
Face-to-face contact
! 1. On drugs
2 Not on drugs
12%
15%
!
Total group 3. On drugs 15%
<35h28%
!
HighEE51%
>35 h 69% 5. On drugs 53%
over the course of 9 months. In view of the the effect on relapse rate of altering rela-
proven efficacy of maintenance neuro- tives' EE from high to low (compare sub-
leptics in preventing relapse of schizophre- groups 1,2, and 3). Hence, the aims of so-
nia (Leff and Wing, 1971; Hogarty and cial intervention were to reduce face-to-
Goldberg, 1973), we considered it unethical face contact below the crucial level of 35 hi
to withhold such drugs from these high-risk week (Brown et aI., 1972) and/or to change
patients. Our strategy then was to ensure relatives' EE from high to low. A range of
that all patients entering the trial received strategies that might be expected to achieve
maintenance neuroleptics in the form of these aims has been set out by Leff (1976).
long-acting injections, to eliminate prob- One possible design for our trial was to as-
lems with compliance. Patients were then sign experimental families randomly to a
randomly assigned to an experimental variety of social interventions, for example,
group, which received the social interven- an educational program, family sessions, or
tion, and a control group, which received behavioral modificaton. We decided that
routine outpatient care. In considering the this was too ambitious in terms of the num-
design, we were faced with the choice of bers required and instead compiled a pack-
administering a nonspecific social treat- age of social interventions which was to be
ment of the control group or allowing their applied flexibly according to the needs of
responsible clinicians to treat them accord- each family. Thus, we set out to compare
ing to their usual practice. Both procedures the relative effectiveness of this package
have their drawbacks, and we chose the lat- with routine outpatient care with the expec-
ter, recognizing that we would need to es- tation that if it did prove to be superior, the
tablish that the treatment experiences of ex- individual elements could be evaluated sep-
perimental and control families were sub- arately in a subsequent trial.
stantially different (cf. Orford and Ed- The intervention basically consisted of
wards, 1977). three elements: an education program, a
relatives' group, and family sessions.
Package of Social Interventions
Education Program
It can be seen from Figure 1 that, provided
low social contact is genuinely protective, This consisted of four lectures on the etiol-
reduction in face-to-face contact between ogy, symptoms, course, and treatment and
high EE relatives and patients on medica- management of schizophrenia. We put a lot
tion should reduce the relapse rate from of thought into the writing of these lectures,
53% to 15%. This would be equivalent to which incorporated our consensus opinions
Controlled Trial of Social Intervention 155
on the above topics, couched in everyday curred after each group meeting.
language with a strict avoidance of jargon. Other reasons for setting up the group in-
The lectures were read out from a type- cluded the need to counter the sense of
script to each relative in his or her home. isolation felt by many relatives of schizo-
Initially four visits were made, one for each phrenic patients, the possibility that the
topic, but after a few relatives had been in- group would allow relatives to discharge
structed in this way, we decided it would be emotions that would otherwise be directed
preferable to give two lectures at a time. at the patients, and the fact that it was eco-
Following each lecture, we allowed unlimit- nomical of resources. The group was con-
ed time for the relative to ask questions. structed to be flexible both in regard to
This element in the package was in fact membership and attendance. Relatives
evaluated separately by means of a knowl- were inducted into the group as the patients
edge interview, administered before and entered the study. The group met every 2
after the education program. This is pres- weeks in a large, comfortable room in the
ented in detail under "assessments." Institute of Psychiatry for 1.5 h, and rela-
tives attended when they could. They were
encouraged to attend for the 9 months of
Relatives' Group the study period, but were free to continue
This was originally conceived of as a way of thereafter if they wished, and a number car-
bringing together high EE and low EE rela- ried on coming for over 1 year. The group
tives. In addition to the family emotion stu- had a maximum of seven members at any
dies, we had evidence from psychophysio- one time and included two professionals for
logical studies (Tarrier, Vaughn, Lader, most of the study, but latterly only one. Our
and Leff, 1979; Sturgeon, Kuipers, Berko- experience with the group is presented in
witz, Turpin, and Leff, 1981) that low EE more detail elsewhere (Berkowitz, Kui-
relatives had found way of coping with the pers, Eberlein-Fries, and Leff, 1981). Each
everyday problems of living with schizo- session was taperecorded, with permission
phrenic patients that not only avoided dis- of the relatives, for future analysis.
tressing the patients but provided them with
active support. Family Sessions
It was our intention to use the group as
a means of altering the coping styles of high Because the relatives' group was not ap-
EE relatives so as to resemble more closely propriate for dealing with the whole range
those of low EE relatives. Some of the of problems or for dynamic work and be-
problems that relatives face were known cause patients were excluded from it, we
from Creer and Wing's (1975) study. Priest- felt that it needed to be complemented by
ley's experiences with a similar group of rel- sessions with the whole family. Conse-
atives were also valuable (Priestley, 1979). quently, we saw each family in their own
Given this information, the group was de- home on a minimum of 1 and a maximum of
liberately set up so that the therapists acted 25 occasions. The sessions, which lasted
as facilitators. Both high EE and low EE 1 h, were conducted by two professionals, a
relatives were encouraged to bring their male psychiatrist and a female psychologist.
problems and their solutions to the meeting Where the key relative was a spouse, we
and share them with others in a similar posi- saw the patient and spouse together. Where
tion. The purpose of this was to enable parents were involved, we saw the patient
them to learn about coping strategies of with both parents if available, and adult sib-
which they were unaware and finally to help lings were also encouraged to participate.
them try a different approach at home. The At the beginning of the study, the value
focus of the group was thus on potential or of family therapy was not well established,
actual difficulties that relatives experienced particularly for the families of schizophreni-
and not primarily on interpretations of the ic patients. Consequently, we adopted a
relatives' own behavior. This latter was pragmatic approach, guided by our princi-
more useful in discussions between the pro- pal aims of reducing EE and/or social con-
fessionals about the group process that oc- tact. Techniques used to achieve these aims
156 J. Leff et al.
Admission Discharge
'V V
1st 2nd 3rd
Proce- knowledge Education knowledge Relatives' Family Follow-up knowledge
dures PSE EE interview interview program interview group sessions EEandPSE interview
Experimental + + + + + + +
High
Control + + + +
Experimental + + + + + +
Low
Control + + + +
_ _ _ _ _ _ _-'9 months..s_ _ _ _ _ __
in family sessions varied from dynamic in- Having passed these screens, patients
terpretations to behavioral interventions. then entered the study, and demographic
Before each session, we discussed and for- and historical data were collected with a
mulated our objectives, but we could be standardized schedule. Relatives in high
diverted from these if other important is- face-to-face contact with the patient (al-
sues emerged in the course of the visit. Each most invariably a spouse or parents) were
session was discussed afterward and a quite interviewed with the abbreviated form of
detailed account written up. the Camberwell Family Interview (Vaughn
In addition to these formal contacts, and Leff, 1976b). Ratings of the four main
some relatives phoned up one or other of us components of EE, criticism, hostility,
on several occasions. We kept careful rec- warmth, and overinvolvement, were made
ords of all such contacts to calculate the from taperecordings of the interviews. Rel-
total amount of professional time taken up atives with a score of six or more critical
by each family. comments, any degree of hostility, or a rat-
ing of 3 or more on overinvolvement1 were
assigned to a high EE group. The further
Assessments
assessments and procedures than ensued
All patients between the ages of 16 and 65 are shown on a flow chart in Figure 2.
admitted to the Bethlem and Maudsley The knowledge interview was specially
Hospital, the Southwestern Hospital, and constructed to test the effect of the educa-
the North Wing at St Pancras Hospital were tion program. It consisted of 21 questions
screened regularly. If they had lived with directly related to the basic information
relatives continuously for 3 months before given in the program. It was administered
admission, resided within reasonable com- before and after the program to experimen-
muting distance from the hospital con- tal high EE and low EE relatives and at the
cerned, and appeared from the case notes same interval to the control relatives. The
to be suffering from a functional psychotic knowledge interview was given a third time
illness, they were interviewed with the Pres- to all relatives at the end ofthe 9-month fol-
ent State Examination (PSE) (Wing, Coo- low-up.
per, and Sartorius, 1974). The PSE data Immediately following the first knowl-
were processed by the CATEGO program, edge interview, a joint interview was held
and those patients assigned a diagnosis of with the relative and patient in a studio.
schizophrenia were included in the trial if in This allowed us to make a videotape record-
addition they spent more than 35 hlweek in ing of the interview, during which certain
face-to-face contact with one or more rela-
tives. This was determined by constructing 1 The crucial level of overinvolvement was lower-
a time budget of a typical week from an in- ed from 4 to 3 prior to the study in the light of
terview with the patient, or failing that with more extensive experience with this rather in-
a relative (Brown et al., 1972). frequent attitude.
Controlled Trial of Social Intervention 157
psychophysiological measures of the pa- a more subjective judgment than the first
tient's respones were made. The data from kind of relapse and hence may be influ-
these interviews will be presented else- enced by the interviewer's bias. Unfortun-
where. ately, it was not possible to maintain blind-
The next step was to give the education ness to each family's status as experimental
program to the experimental high EE and or control because the research team was
low EE relatives. When this was com- both conducting the intervention and mak-
pleted, the relatives were invited to join the rng the assessments. This deficiency in the
relatives' group. At about this time, most design could only have been remedied by a
patients were close to discharge from the considerable increase in staff, which was
hospital. For all high EE families, the clin- not feasible. However, there were a num-
icians responsible for the patients were in- ber of safeguards against the influence of
formed of their high risk of relapse and bias. The key assessments, EE and the
were asked to prescribe long-acting neuro- PSE, were made by researchers who were
leptic medication if possible. It must be extremely experienced in the use of the
appreciated that patients remained under techniques and had been trained to a high
the care of their usual clinician. Our thera- level of interrater reliability.
peutic interventions with the experimental The assessment of EE was usually con-
families were conducted in parallel with the ducted independently by two raters. Where
patients' ordinary clinical care and de- they disagreed or where the rating was par-
pended on a close liaison with the clinical ticularly crucial, the recording was sent to
team. This was usually, but not invariably, a Dr Christine Vaughn, who rated it blindly.
successful arrangement. In addition, a representative selection of
Just before discharge, the patient's clin- eight follow-up interviews was rated blindly
ical state was assessed. If it was clear that by Dr R. Gosh, who had been trained in the
the psychosis had completely resolved, an assessment of EE. His reliability with the
informal assessment was carried out. How- definitive raters was calculated using the
ever, if there were any residual pychotic product moment correlation coefficient and
symptoms, a full PSE was conducted and was found to be 0.88 for critical comments
served as a baseline for any subsequent and 0.90 for overinvolvement. He agreed
change. Following discharge, virtually all with the definitive raters on the assignment
the patients attended outpatient clinics on a to high or low EE in seven of the eight
regular basis. A note was affixed to their cases. In the eighth case, he rated one ex-
case records asking the responsible clini- perimental mother as marginally high on
cian to contact the research team if there criticism whereas she had been rated as low
was any suggestion of an impending or by both definitive raters independently.
actual relapse. As a result, it was possible to With regard to the PSE ratings, these
see all but one of the patients who suffered were not done blindly in the case of a type 1
a recrudescence of symptoms at an early relapse. However, for possible type 2 re-
stage in their relapse. A full PSE was per- lapses, an independent rater, Dr Paul Beb-
formed at the time and a history of life bington, was recruited to make the assess-
events taken for the 3 months prior to re- ments blindly. He did not always concur
lapse (Brown and Birley, 1968). with the view of the patient's clinician that a
For the purposes of the research, relapse relapse had occurred.
was defined as a recurrence of schizophren-
ic symptoms as detected by the PSE, in pa-
Follow-up
tients who had been free of them at dis-
charge (type 1 relapse of Brown et al., All patients in the trial were followed up at
1972). For the small proportion of patients 9 months after discharge. If they had not al-
who still had active schizophrenic symp- ready relapsed, a PSE and life events his-
toms at discharge (two experimental, three tory were administered. The relative or rel-
control), relapse was defined as a marked atives were reinterviewed with the Camber-
increase in the number or intensity of symp- well Family Interview, if possible by the
toms (type II relapse). This clearly involves same person as on the first occasion, and
158 J. Leff et al.
EE was rated. The time budget was also A 2-year follow-up has also been initia-
repeated. A history of medication taken by ted, the results of which will be presented
the patient during the preceding 9 months when it is completed.
was obtained.
Subjects
nificant difference between the two groups,
Characteristics of Patients
once more confirming the truly random
Over the course of 4 years, 49 patients pas- nature of patient assignment. In terms of
sed the screening criteria for the trial. The CATEGO classes, 11 patients in each
number is so small because our selection group were labeled S+ (schizophrenia),
procedures for high-risk patients eliminated while the remaining patient in each group
more than two of every three admissions for was classified as P+ (paranoid psychosis).
schizophrenia. Of those families ap-
proached, nine (18%) refused to take part
Characteristics of Relatives
in the study. Of the remainder, 24 lived with
high EE relatives and actually participated In the experimental group, six patients
in the trial. The randomization procedure, lived with a spouse and six with parents. In
using a table of random numbers, segregat- the control group, six lived with a spouse,
ed them into 12 control and 12 experimental five with parents, and one with her sister.
families. Relatives who were found to be Some patients in both groups lived with a
low EE from the Camberwell Family Inter- single parent, and in some households one
view were also randomly assigned to ex- of the parents was in low face-to-face con-
perimental and control groups for the pur- tact with the patient, in which case they
pose of assessing the effects of the educa-
tion program (see Figure 2). In addition,
the low EE experimental families were en- Table 1. Demographic and Historical Charac-
couraged to join the relatives' group, in ac- teristics of Patients
cord with the principal therapeutic aim of Experi- Control
identifying and using their coping skills as a mental
model.
Number 12 12
Male/female 6/6 6/6
Demographic and Historical Data Living group: parents 6 6
spouse/sibling 6 6
The experimental and control patients were Mean age 39 30
compared on a large number of demo- Education: CSE or above 4 4
graphic and historical features as shown in Ever married 6 7
Table 1. Except for unemployment, which Ever divorced or separated 1 2
was worse in the experimental group, none Mean number of children 0.8 1.3
of the items differed significantly between Drop from highest sociosexual
the two groups, endorsing the effectiveness achievement 3 2
ofthe randomization procedure. Occupation: nonmanual or
above 6 2
Mean length of unemployment
Clinical Data before admission in months 16.5 4.8'
Employed at admission 4 7
The PSE data were processed by the Abnormal premorbid
CATEGO program and a print-out ob- personality 8 5
tained of syndromes and of diagnostic clas- First admission 4 4
ses. The experimental and control patients Mean number of previous
were compared for the presence or absence admissions 2.3 1.2
of each of the 38 syndromes using Fisher's Age at first onset 33 27
exact test. For no syndrome was there a sig- • P<0.05.
Controlled Trial of Social Intervention 1S9
Table 3. Overinvolvement Scores of Experimental and Control Relatives
Number of relatives Mean number of critical comments
with six or more
critical comments At9-month
initially Initially follow-up
were not interviewed for an EE assessment. scores for these individuals are shown in
A total of 13 relatives in the experimental Tables 2 and 3. There were no significant
group and 13 in the control group were differences between the groups on these
rated on EE. The mean number of critical measures.
comments and the mean overinvolvement
Results
Social Intervention
only one family had as many as 25 sessions.
Two relatives did not attend the group at In addition to the formal contacts of the
all. One, a wife, attended for the first time relatives' group and family sessions, rela-
on the only occasion when no other rela- tives were encouraged to phone members
tives turned up. She was given a one-to-one of the team whenever they felt the need.
session with the therapist and declined This facility was not abused as a total of 10
further attendance or contact. She was the relatives used this method of contact be-
only relative who did not receive the educa- tween 2 and 19 times, the mean being 7.5
tion program. The other, a husband, was times.
managing a business which demanded his Apart from our own efforts to work with
presence at the time the group met. The re- the relatives in the experimental group, the
maining 11 high EE relatives attended the clinical team responsible for the patient's
group an average of 9.1 times ranging from care provided some input in two cases. For
6- 21 times over the 9-month follow-up pe- one married couple, the clinical team's so-
riod. The number of relatives present at cial worker acted as a co-therapist with
each session varied from two to seven, with one of the research psychologists, as he
a mode of four. wished to gain experience of mariti thera-
Family sessions in the home wee held for py. Another married couple received mari-
all families. The number of sessions ranged tal therapy from the clinical psychiatrist in
from 1 to 25 with a mean of 5.6. However, parallel with our own family sessions. We
160 J. Leff et al.
took pains to maintain a close liaison with went through the planned assessment pro-
this therapist. cedures at the 9-month follow-up. 2-year
The therapeutic experiences of the con- follow-up has been completed and will be
trol relatives were studied by consulting the presented elsewhere (Leff, Kuipers, Ber-
case notes of the patients as well as ques- kowitz, and Sturgeon, in press).
tioning the relatives at follow-up. The control relatives were not as cooper-
ative as their experimental counterp!lrts,
probably because we offered them no help.
Treatment Experiences of Control
Two of the 13 originally interviewed re-
Relatives
fused a second EE interview, and one, a
In eight cases, no therapeutic help was husband, had left his wife and was unob-
given to the relatives. In two cases, the rela- tainable. Thus the success rate for follow-
tives themselves were seen by a psychiatrist up was 77%.
to receive treatment for overt symptoms. The mean number of critical comments
One relative, the mother of a schizophrenic and the overinvolvement scores obtained at
girl, was discovered to suffer from schizo- follow-up are shown in Tables 2 and 3. It is
phrenia herself and was treated as an outpa- evident that there has been a highly signifi-
tient with a neuroleptic drug. She attended cant reduction in criticism in the experi-
a total of 11 times in the course of 9 months, mental group over the 9-month period of
but the focus of treatment was on her psych- social intervention. Five experimental rela-
iatric condition rather than on her attitudes tives changed from high to low criticism,
toward her daughter. The other relative to while three others showed some decrease.
receive treatment was a husband who be- Only three critical relatives remained vir-
came depressed and was seen as an outpa- tually unchanged. By contrast, there was a
tient on several occasions over 2 months. small and nonsignificant reduction in the
Two further families received help from number of critical comments made by the
social workers. In one family, this took the control relatives. This was entirely account-
form of a single family session held during ed for by two relatives, one a spouse and
the 9th month after the patient was dis- one a sister, who changed from high to low
charged with the aim of persuading him to criticism. As neither relative had received
attend a day hospital. In the second family, any therapeutic help from professionals,
the wife of a schizophrenic patient was seen this almost certainly represents a spontane-
every 2 weeks by a psychiatric social work- ous alteration in attitude.
er, and one family session was held during We can conclude from these data that our
the 9 months. The social worker wrote that package of social interventions met with
"my interviews with her have had the object considerable success in ameliorating critical
of providing her with some support through attitudes in the experimental relatives. The
helping her to share her feeling of responsi- same cannot be said for emotional overin-
bility for maintaining her husband's pro- volvement. There was a drop in the mean
gress." He gave her some advice on how to overinvolvement score for the experimental
handle her husband's behavior that stem- relatives, as can be seen from Table 3, but
med from his delusions. It is only in this this failed to reach an acceptable level of
single case of the 12 controls that profes- significance. In terms of individuals, two
sional help to the relatives approximated relatives altered from high to low scores on
that received by the experimental families. overinvolvement. One of these, the only
It is worth noting that in this control case spouse to show overinvolvement in the ex-
the wife's level of overinvolvement actually perimental group, underwent a particularly
rose during the follow-up period, although dramatic change from a score of 4 to zero.
her husband reduced his contact with her to Two others achieved a lower score, but did
a low level. not drop below 3, while one relative showed
no change. By contrast, none of the overin-
volved control relatives fell below 3 on this
FoUow-up Relatives
scale, while one relative actually changed
All relatives in the experimental group from low to high during the follow-up period.
Controlled Trial of Social Intervention 161
At follow-up, face-to-face contact had of neuroleptics and received these regularly
fallen below 35 hlweek in six experimental as prescribed. One control patient with a
relatives, two being the parents of one pa- first episode of a paranoid psychosis was
tient. In one patient, this reduction resulted prescribed oral trifluoperazine, which he
from his getting a full-time job and in anoth- took religiously, while one experimental
er from attendance at a day hospital, while patient could not tolerate the side effects of
the remaining three made alterations in the injections and was transferred to oral med-
ways they spent their leisure time. Low con- ication. She also adhered meticulously to
tact was also found at follow-up in three her drug regime.
control families, which is not significantly
During the 9-month follow-up, relapse
different from the proportion in experi-
occurred in seven patients, six of them in
mental families. However, in two of these,
the control group. All relapse were type 1 in
the way in which this was achieved was dif-
nature. In six patients, the relapse took the
ferent from that in the experimental group.
form of a florid episode, similar if not ident-
One patient's husband left her during the
ical to the previous one. Three of these pa-
follow-up period, while another patient
tients were readmitted to the hospital. The
began spending most of his leisure time
seventh patient, a control case, had been
alone in his room. The third patient de-
free of auditory hallucinations, which re-
veloped more leisure interests which took
turned abruptly. The relapse rate in the
him out of the parental home.
control group was 50%, while the rate in the
As stated earlier, the aims of the social in-
total experimental group was 8% (exact
tervention were to lower EE and/or face-to-
P = 0.032). Hence, the package of social
face contact below certain crucial levels. interventions produced a significant reduc-
Reduction of EE was achieved in five famil- tion in relapse rate of schizophrenia. Furth-
ies and reduction of contact also in five fam-
er light is thrown on the specificity of the
ilies, but there was some overlap, as can be
interventions by comparing the relapse rate
seen in Table 4.
in the control group with that of the patients
As a consequence, one or both of our
in whose families we achieved one or both
aims were met in 9 of the 12 families with
of the aims of social intervention. In fact, in
follow-up completed to date. Hence, social
these nine families not a single patient re-
intervention was successful with 75% of
lapsed, a difference from the relapse rate in
families. the control group of even greater signifi-
cance (exact P = 0.017).
FoUow-up Patients The single experimental patient who re-
In each group, all but one of the patients lapsed was living in high contact with her
were maintained on long-acting injections mother, who was both highly critical and
Discussion
The screening procedure for our trial was Rodnick, Evans, May, and Steinberg
calculated to select patients with schiz- (1978), Hogarty, Goldberg, Schooler, and
ophrenia who were at high risk of relapse. Ulrich (1974) and Hogarty, Schooler,
The effectiveness of the procedure was sub- Ulrich, Mussare, Ferro, and Herron (1979)
stantiated by the relapse rate of 50% over 9 satisfy reasonably stringent scientific crite-
months in the control group, despite the ria. Goldstein and his colleagues studied
fact that they were all maintained regularly schizophrenic patients in their first or se-
on neuroleptic drugs. The significantly and cond admission so that it is inevitable that
substantially lower relapse rate of 8% in the their average age, 23, was considerably
experimental group provides evidence for lower than that of our sample, 35. Their pa-
the therapeutic effectiveness of our pack- tients were discharged after an admission of
age of social interventions. However, we only 1-2 weeks on long-acting injections of
did not achieve our aims of lowering EE fluphenazine. The experimental subjects
and/or social contact in every family, but received six sessions of crisis-oriented fami-
only in three-quarters of them. It is notable ly therapy, with the primary goal of helping
that in this smaller group of nine families no the patient and significant others use the
patient relapsed. The single relapse of an events of the psychosis to adjust to the ill-
experimental patient occurred in one of the ness. At a 6-month follow-up, no patient in
three families in which neither EE nor so- the drug plus family therapy group had re-
cial contact was lowered to the target level. lapsed, whereas the relapse rate among pa-
This shows that the achievement of one or tients who received the drug alone was 18%
both of our stated aims was crucial for a (P = 0.04). The interpretation of this result
therapeutic effect. is slightly clouded by the fact that the thera-
The specificity of our therapeutic en- py received by both groups was not stand-
deavor in totally preventing relapse of schi- ardized after the initial6-week trial period.
zophrenia in a high-risk group over 9 In the two studies of Hogarty and his col-
months provides unequivocal evidence leagues, social therapies were also added to
both for the causal influence of high EE rel- maintenance neuroleptic drugs in a con-
atives on relapse and for the protective ef- trolled design. Their patients were more
fect of lowered social contact between pa- like ours than were Goldstein's, being
tient and relative. Our tentative interpreta- mainly chronic and having a median of
tion of the data in Figure 1 (Vaughn and three previous hospital admissions. In the
Leff, 1976a) now takes on a definitive sta- first study, the social therapy was a com-
tus, all the more so because the relapse bination of intensive social casework and
rates predicted from the Figure were so vocational rehabilitation counseling, while
close to the actual rates (53% cf. 50%,15% in the second it comprised intensive individ-
cf.8%). ual and family social casework. In neither
It needs to be emphasized that our find- study did the social intervention significant-
ings not only constitute evidence for the ly reduce the relapse rate when added to
causal influence of relatives' EE on the maintenance drugs. However, it did appear
schizophrenic process in patients, but also to confer an advantage on the patients in
substantiate the effectiveness of a form of the 2nd year of the follow-up, no relapse oc-
social intervention with these families. To curring during this period among patients
date, the evidence for this has been some- receiving social therapy and drugs in both
what sparse. Only the studies by Goldstein, studies.
Controlled Trial of Social Intervention 163
Our result is thus closer to that of Gold- detectable by monitoring the patients' auto-
stein et aI., although we were studying a nomic responses (Tarrier et aI., 1979; Stur-
more chronic population in remission rath- geon et aI., 1981). An "arousal" hypothesis
er than in the throes of a psychosis, and fur- has been proposed to accommodate these
thermore our subjects were selected to re- findings and work has recently begun using
present a particularly high-risk group. This this paradigm to study cortical psycho-
difference is pointed up by comparing the physiology.
relapse rate of our control group over 9 There are a number of practical issues,
months, 50%, with that of Goldstein's con- the first of which concerns our failures in
trol patients over 6 months, 18%. the experimental group. With hindsight
Our findings have important implica- could we have been more effective in work-
tions, both theoretical and practical. On the ing with the three families concerned, bear-
theoretical side, now that the role of rela- ing in mind our lack of experience with
tives' emotional attitudes has been firmly these kinds of families when we began the
established in the causation of schizophren- study? The answer for one family is possibly
ic relapse, the question arises of whether yes. This was a marital couple where the
they operate in a similar manner prior to the husband was the patient. They received
first episode. It is logically inadmissable to marital therapy from the clinical psychia-
extrapolate our findings backward in time trist in parallel with our sessions of family
to before the first attack of illness since this therapy. It is possible that this diversifica-
itself may dramatically alter relatives' at- tion of effort weakened the potency of the
titudes. However, evidence exists linking two sets of therapists, and more would have
one emotional attitude we found to be in- been achieved with a single set.
fluential, with maternal overprotectiveness The other two families shared a number
antedating the onset of schizophrenia. This of features in common: they both had multi-
evidence, which derives from child guid- ple problems, the patient was a single girl in
ance clinic studies, was reviewed by Hirsch both, and the key relative was a mother who
and Leff (1975) who concluded that over- was both excessively critical and overin-
protective attitudes were more commonly volved. In one family, already, referred to,
shown by mothers of children who later the patient had Turner's syndrome in addi-
develop schizophrenia than mothers of con- tion to schizophrenia, and the mother had
trol children. There is a clear link between shown overinvolved attitudes to her almost
this early overprotectiveness and an aspect from birth. In the other, the mother was Ita-
of overinvolvement, as measured in the stu- lian and spoke broken English, and it was
dies of EE. This suggests that the overpro- doubtful, in retrospect, whether she took in
tective component of overinvolvement much of what went on in the relatives'
develops very early in the child's life, and group and family sessions.
indeed we have anecdotal evidence of this In the first of these two families, the pa-
from several of our families. It is likely that tient relapsed after only 2 months at home
the long-standing nature of this component and before her mother had started to attend
of maternal overinvolvement accounts for the relatives' group. This was an unusual
the lesser degree of success we had in alter- delay and may have been symptomatic of
ing this attitude when compared with our the mother's resistance to therapy. In fact,
effect on criticism. The single dramatic dis- we continued working with the family fol-
appearance of overinvolvement was not in a lowing the patient's relapse, and after a
mother but in a wife, who would of neces- year or more there are some indications of
sity have held this attitude for a much short- change in the mother's attitudes. These will
er period of time. be assessed at the 2-year follow-up. The
The other theoretical consideration is the second of these two families, with the ita-
mechanism by which relatives' attitudes lian mother, we felt would probably have
produce a recurrence or exacerbation of resisted the efforts of the most experienced
schizophrenic symptoms in the patients. therapist. However, someone who was
Previous studies have established that the bilingual in English and Italian might well
effect of high EE relatives on patients is have breached the communication barrier.
164 J. Leff et al.
The other two practical issues are closely requires no special training and could read-
connected: which element in our package ily be introduced as part of the history tak-
was the most effective, and what should be ing. In choosing between the strategies of
taught to professionals who intend to work attempting to reduce face-to-face contact or
with the families of schizophrenic patients? to lower EE, it might be assumed that the
We cannot answer the first question fully former was the easier and less time-con-
since we did not evaluate the individual ele- suming option. Indeed, we began the trial
ments of our package, apart from the edu- with this explicit assumption. However, we
cation program. In the absence of this infor- found that a number of families were very
mation' we have to assume that the rela- reluctant to spend less time together and yet
tives' group and family sessions are of equal responded to our attempts to reduce EE. In
importance. Working with families would other families, we felt that a reduction in
appear to require a longer training than the contact only became possible when the
running of relatives' groups, but it must be emotional bonds tying them together had
appreciated that we had little experience in been loosened. As it turned out, we were
either form of therapy with families of schi- equally successful in achieving both aims so
zophrenic patients when we started and yet would recommend their joint adoption by
managed to achieve a high success rate in clinicians.
meeting our aims. We consider that part of From the beginning, we have been sensi-
the formula for success is the setting out of ble of the need to keep our interventions
clear aims from the beginning, and anyone within the scope of everyday clinical prac-
entering this area of clinical work should tice. We attach such great practical impor-
have as a target the reduction of face-to- tance to the result of our trial that we see
face contact and of critical and overin- our next task as the compilation of a train-
volved attitudes in the relatives. ing program that will make the necessary
The clinician is faced with the problem skills available to social workers, clinical
of deciding which families need this kind of psychologists, and psychiatric nurses.
approach. Unfortunately, the training re-
quired to rate EE is a long and arduous pro-
cess so that the Camberwell Family Inter- Acknowledgment. We are grateful to the consult-
ants at the Bethlem and Maudsley Hospital, the
view cannot be incorporated routinely into Southwestern Hospital, and the North Wing at St
clinical assessment. However, most high Pancras Hospital who allowed their patients to
EE families are readily identified by clin- take part in this study. Our thanks are due to Dr.
icians, even those unfamiliar with the con- Bebbington for carrying out PSE assessments on
cepts of criticism and overinvolvement. some patients and to Dr. Vaughn and Dr. Ghosh
Families with borderline levels on these sca- for conducting EE assessments on some relatives'
les are likely to be missed in clinical prac- interviews.
tice, but the clinician should be alerted to An extended version of J. Leff, L. Kuipers, R.
the possibility that relatives are high EE if Berkowitz, R. Eberlein-Vries, and D. Sturgeon,
"A Controlled Trial of Social Intervention in the
patients living with them require frequent Families of Schizophrenic Patients". British
readmissions despite prophylactic medic- Journal of Psychiatry, 1982, 141, 121-134. Copy-
ation. right 1982. The Royal College of Psychiatrists.
The determination of the degree of face- Reprinted by permission of authors and pub-
to-face contact is a simple procedure which lisher.
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Appendix
Experimental Families
Case 1 Mother I: Cll, 03; F: Cl, 02. Case 3 Wife I: C26; F: Cll.
Stepfather I: C9; F: C2.
The patient, a married man of 42, had been
The patient, a man of 23 living with mother, step- admitted six times before the current episode of
father, and a younger brother, suffered a first at- schizophrenia. He had not been able to work in
tack of schizophrenia. Mother had always seen the preceding 18 months. There were three chil-
him as the weaker of her two sons and appeared dren, with the eldest of whom, a daughter, he had
to have been overinvolved with him virtually had an incestuous relationship some years previ-
from birth. He slept in her bed till the age of 15. ously. This had come to light and he had served a
He was discharged from the hospital to a hostel, prison sentence. His wife was very intolerant of
but left after a few weeks to return home. How- his handicaps and extremely critical of his inabili-
ever, he attended a day hospital so that contact ty to playa man's role in the family. She used the
remained low. Family sessions included his par- group to vent a great deal of anger. Family ses-
ents and brother and focused on the marital rela- sions were held, sometimes including the chil-
tionship, which was initially poor, but improved. dren, but our attempts to persuade patient and
The patient was free of psychotic symptoms on wife to spend less time together were unsuccess-
discharge and remained so throughout the 9 ful. Although she welcomed the opportunity to
months. go out in the evening, he both refused to ac-
company her and made her feel guilty about leav-
ing him. At follow-up, her criticism had consid-
Case 2 Husband I: C9; F: CO. erably abated, although not below the crucial
The patient, a married woman of 53, experienced level, and they remained in high contact. Never-
a second episode of schizophrenia. Her husband, theless, he remained free of psychotic symptoms,
a retired professional and an intelligent, emo- although he continued to exhibit a significant de-
tionally inhibited man, was extremely intolerant gree of depression.
of her irrationality when she was ill. He attended
the group regularly, and in addition we conduct-
Case 4 Wife I: C7, 01; F: C2, 01.
ed joint sessions in the home, but we were never
able to explore the emotional roots of his in- The patient, a married man of 47, was admitted
tolerance. Nevertheless, his critical attitude had on the second occasion for an episode of paranoid
disappeared at follow-up, and his wife remained schizophrenia. He believed that the neighbors
free of all symptoms. They continued to be in downstairs were interfering with his apartment in
high contact despite her joining day classes, and various ways, a belief that his wife shared, thus
his taking up a part-time teaching job. exhibiting folie Ii deux. He had retired from his
Appendix 167
job as a caterer 3 years earlier on account of phy- Case 7 Mother I: C16, 01; F: C3, 02.
sical ill health. One conjoint marital session was
held, following which his wife attended the group The patient, a divorced woman of 42, lived with
on a single occasion, but as no other relatives ar- her elderly mother and was admitted for the first
rived that time, she was given an individual ses- time with an episode of schizophrenia. A younger
sion by the psychologist. She refused to come to sister had suffered from schizophrenia for many
the group again. The patient lost his paranoid de- years and had eventually committed suicide. The
lusions while in the hospital, and his wife's abnor- patient slept in the same bedroom as her mother,
mal beliefs also disappered. He remained well who was very critical of her. The patient was also
and at follow-up was found to be in low contact as physically disabled by chronic bronchitis and was
he had increased the time spent going out on his unable to work. Her mother attended the group
own. regularly, and sessions were also held in the
home. In particular, we attempted to persuade
the patient to move into a bedroom of her own
and to influence her mother to allow her to do
Case 5 Wife I: C8; F: C9. more for herself in the home. We made efforts to
The patient, a married man of 55, was admitted get the patient to attend a day center, but she was
for the first time with an acute and florid attack of very resistant to this, so instead we arranged for
schizophrenia. He had been unemployed for 3 her to come to the hospital daily as a day patient.
years having lost his job as a chauffeur through a At follow-up, she was spending much less time
drinking and driving offence. He had married his with her mother, although still in high contact.
wife when she was pregnant with another man's Her mother had become much less critical,
child, and they had had four children of their though was slightly more overinvolved and they
own. His wife was critical of him and showed little still slept in the same room. At discharge, the
warmth. She attended the group regularly, and patient was hearing voices continuously despite a
we held several conjoint marital sessions, but at high dose of a phenothiazine. The voices gradual-
follow-up her critical attitudes were unaltered ly attenuated over the course of 9 months and
and the marital relationship appeared to be were much less insistent and frequent at follow-
unchanged. However, the patient had taken on a up.
job as a security guard and because of the shifts he
worked was in low contact for 5 of every 6 weeks.
He remained free of psychotic symptoms
throughout the 9 months.
Case 6 Wife I: C3, 04; F: C1, 00. Case 8 Husband I: C26; F: C15.
The patient, a married man of 56, was admitted The patient, a married woman of 44, was admit-
for the tenth time with a psychotic illness. In the ted for the sixth time with an attack of schizo-
past, his diagnosis had varied between schizo- phrenia. She and her husband ran a hotel and
phrenia, mania, and schizoaffective psychosis. both abused alcohol. However, there was no
On this occasion, he had first-rank symptoms as doubt of the schizophrenic nature of her illness.
well as grandiose delusions and was diagnosed by He was exceedingly critical of her, and they often
CATEGO as S+. His wife had been a social had physical fights. Because of their work, the
worker and gave up her job on marrying him 6 husband could not attend the group, so instead
years previously. It was evident that she treated regular conjoint marital sessions were arranged
him as though he was her client, and this was re- to fit in with the couple's working hours. These
flected in her overinvolvement with him. He had were conducted by a female research psycholo-
given up his job as a commercial artist 7 years gist and a male staff social worker. After a while,
previously and did clerical work part-time. His it was decided that each therapist would see the
wife attended the group regularly, and in addi- same-sex client on an individual basis in place of
tion, we held one conjoint marital session in the joint sessions. The couple owned a house in
which the patient's feelings of inadequacy and his addition to living in the hotel and were encour-
wife's need to protect him were explored. This aged to spend more time in their house, where
appeared to have a significant effect as shortly they tended to occupy separate rooms. As a con-
afterward she returned to full-time work. He con- sequence, at follow-up they were in low contact.
tinued to work part-time at home and remained The husband's criticism had abated considerably
in high contact with his wife, but at follow-up her but was still well above the safe level. The patient
overinvolvement had completely dissipated. The had no recurrence of symptoms during the 9
patient remained well. months.
168 Appendix
Case 9 Mother I: C41, 04; F: Cll, 03. spoke broken English, while the patient was
Father - low contact. bilingual. Her father, a caretaker, spent long
hours away from the home. The patient was ad-
The patient, a youth of 20, lived with his parents mitted for the third time with an acute episode of
and two siblings. His father, an engineer, worked schizophrenia. Her mother had few friends, took
long hours, and they spent little time together. the patient with her wherever she went, and
He was admitted with a first episode of schizo- clearly treated her as her principal companion.
phrenia and was markedly overactive, running They slept in the same bed, while the father was
away from the hospital on several occasions. His banished to another room. Her mother joined the
mother was one of the most critical relatives in group and several family sessions were held, in-
the study and was also highly overinvolved. She cluding the brother. Communication in these ses-
attended the group regularly, and we also held sions were held, including the brother. Com-
several sessions with the patient and both his munication in these sessions was very disrupted,
parents. Although he recovered from the acute and we put a lot of effort into clarifying it. It pro-
episode, the patient continued to complain of ved very difficult to engage her father in the
apathy and anhedonia throughout the follow-up therapeutic program. At follow-up, the mother's
period. He improved very slowly, began to at- attitudes were unaltered, and she remained in
tend the hospital as a day patient, and started high contact with the patient. Nevertheless, there
playing squash and taking up the piano again. At had been no relapse.
follow-up, his mother showed a reduction in both
elements of EE, but not below the crucial levels.
However, the patient was found to be in low con- Case U Mother I: C27; F: C3, 02.
tact with her, as well as with his father, and suf- The patient, a single woman of 41, lived with her
fered no return of the florid symptoms of his ill- mother. She was admitted for the second time
ness. with an episode of schizophrenia. The patient's
mother was extremely critical of her, but she
spent all her leisure time with her. Her mother
Case 10 Mother I: C15, 05; F: C14, 03. received the education program and was a regu-
The patient, a woman of 25, lived with her lar attender at the group. The group terminated
mother and mother's boyfriend, her father hav- before the follow-up was due, and a research psy-
ing committed suicide in a psychiatric institution. chologist saw the mother and daughter every 2
The patient suffered from Turner's syndrome re- weeks for the rest of the follow-up period. This
sulting in dwarfism, as well as schizophrenia. She patient was in the hospital for nearly 1 year and
was admitted for the third time. Her mother had appeared at times to be at risk of becoming in-
always been overprotective, and this had been stitutionalized. At discharge, she was free from
intensified with the advent of schizophrenia. Her florid symptoms but showed blunting of affect
mother was also excessively critical. It proved dif- and no spontaneous speech. She had been work-
ficult to get the mother to attend the group and ing prior to her admission, but was too handi-
before she did so, the patient relapsed with a re- capped to resume work and attended a day hospi-
currence of florid symptoms during a weekend tal three times a week and a day center twice a
together at a holiday caravan. This occurred 2 week. Much of the therapeutic work was aimed at
months after discharge and was the only relapse enabling the patient to become more active, to
in the experimental group. Following this, her get up in the morning at a reasonable hour, and to
mother began to attend the group regularly, and do some household tasks. In addition, our aim
we held several family sessions. At follow-up, the was to help the mother to encourage her daughter
mother's criticism was unchanged, though she in these activities and to persevere with her ef-
was considerably less overinvolved. However, forts. At the 9-month follow-up, the mother sho-
she and the patient were still in high contact. wed very little criticism although she was a little
more emotionally overinvolved. The patient ex-
perienced no recurrence of florid symptoms dur-
Case 11 Mother I: C6, 04; F: C7, 04. ing the 9-month follow-up period. Her affect re-
Father - low contact. mained rather restricted, but she showed much
more spontaneous speech, had resumed some
The patient, a woman of 23, lived with her par- hobbies such as knitting, helped with chores, and
ents and a brother. Her mother was Italian and in particular kept her own room clean and tidy.
Appendix 169
Control Families
Introduction
Behavioral family therapy represents a focus on manifest weaknesses. It is assumed
clear departure from the focus on "ab- that in very situation each family member is
normal" family interaction patterns that has doing his or her best to cope with the stres-
played a prominent role in the psycho- sors that they are experiencing. Their abil-
dynamic and non behavioral family theories ity to achieve ideal solutions and goals is
of schizophrenia. Research and clinical limited by a broad range of personal and en-
practice, especially with psychodynamic vironmental constraint, such as intelli-
and systemic methods, have sought to gence, past experience, education, social
examine the detrimental effects of family learning, interpersonal role patterns, and
transactions upon the family member who finances. It is assumed that they will en-
is experiencing the symptoms of schizo- deavor to fashion the most effective re-
phrenia (Fromm-Reichmann, 1948; Lidz, sponses from all the resources within their
Fleck, and Cornelison, 1965; Jackson and group. However, it is recognized that under
Weakland, 1960; Wynne, Ryckoff, Day, the added strain of having one (or more)
and Hirsch, 1958). Despite formulations to family member(s) suffering from a major
the contrary, the paradoxical approaches of illness that the capacity for efficient prob-
the Milan group (Selvini-Palazzoli, Ce- lem solving will be eroded, sometimes to
chin, Prata, and Boscolo, 1978) have tend- the point where other individuals in the
ed to instigate change through the parents family may decompensate and become phy-
of disturbed index patients, indirectly im- sically or mentally ill under the burden.
plicating their behavior as detrimental. On This is particularly so when the symptoms
the other hand, the behavioral family thera- are persistent and disruptive to the usual
py approach proposes that the family is the pattern of family interaction. Thus, it may
basic unit for the promotion of the healthy not be sufficient for the family of a chron-
functioning of all its members, and it is a ically ill person to function as an average
crucial determinant in the recovery and re- problem-solving unit; indeed, they may
habilitation of those suffering from illness. need to achieve much greater than "nor-
This natural care giving function of families mal" family functioning to preserve their
is considered to be the greatest resource own health as well as restore the health of
available to the mental health services. the sick member. This paradigm of effective
For this reason, the behavioral family problem solving in families alters, in a fun-
therapy approach seeks first to evaluate the damental fashion, the way we assess family
healthy elements of family communication functioning and subsequently formulate
in solving everyday problems before assist- our therapeutic interventions. The goal is
ing the family to enhance their problem- not merely to ameliorate symptoms through
solving efficiency. Minimal attention is reducing stress in the environment, but also
accorded to patently ineffective problem- the enhance the functioning of each mem-
solving strategies. The aim is to build upon ber of the family unit.
pre-existing family strenghts, rather than
172 I. R. H. Falloon
Behavioral Analysis of Family Functioning
The first step in behavioral family therapy This is the first time the family is brought
involves an assessment of the strenghts and together as a group. Previous assessments
weaknesses of the family as a problem-solv- of individual family members may have re-
ing unit. Particular note is made of the pre- vealed reports of problem-solving efforts,
cise manner in which they tackle the prob- but such reports provide only a sketchy
lems of everyday life together, as well as view of family discussions from highly sub-
their responses to significant life events. jective viewpoints. We have employed
Life problems include the personal goals of several methods to obtain naturalistic ob-
individual family members. servation of family problem-solving behav-
Initially, family members are interviewed ior. Perhaps the best has been obtained
individually to establish their unique assets from observing the family in their home.
and deficits, their personal life goals, and Occasionally this is not feasible, and clinic-
the assistance they obtain from other family based analogues have been used. It is im-
members in their attempts to achieve these portant to realize that families may not pro-
goals. Their feelings and attitudes toward vide valid evidence of their functioning
other family members are discussed. The within the constraints of the clinic and that
Camberwell Family Interview (CFI) provi- at least one home visit is crucial in their as-
des a useful adjunct to this individual analy- sesment. The problem-solving test that we
sis, although in its abbreviated form have found most useful involves carefully
(Vaughn and Leff, 1976a) it focuses on re- choosing a "hot issue" that concerns all
lationships with the index family member family members and leaving them to at-
and his or her behavioral disturbance. tempt to resolve the problem within a 10-
The second step in behavioral analysis of min period. This time interval is often too
a family unit involves an assessment of the brief to allow detailed planning to be achie-
relationships between the various goals and ved but provides a surprisingly good insight
problems of individual family members. It into the structure and strategies the families
is clear that the aspirations of individual employ in their discussions. The strengths
family members may conflict at times with and weaknesses of the family's communica-
the wishes and values of other family mem- tion and problem-solving skills can be relia-
bers. An insecure mother may not want her bly coded for clinical and research analysis.
son or daughter to leave her and go to work Once these steps have been undertaken,
or a day center every day. often over several weeks, and up to 20 h of
Strictly religious parents may be upset by intensive assessment, the behavioral family
social activities that involve drinking or therapist is in a position to formulate a
sexual contact. Such conflicts with individ- management plan that is uniquely structur-
uals' goals for themselves and one another ed to enhance the problem-solving efficien-
may undermine progress unless they can be cy of each family unit. The current efforts of
resolved by effective problem solving. families to cope with their problems and
Seemingly positive changes, from a thera- achieve their goals are documented, and
pist's perspective, may be perceived dif- these serve as the basis upon which to con-
ferently by the family as a whole. It is, struct increasingly effective problem solv-
therefore, crucial that the therapist can for- ing. This base line behavioral analysis is
see these potential problems at the onset of merely the initial phase of the program, and
intervention and can help the family to seek throughout the course of treatment similar
creative solutions at an early stage. This assessment of family functioning continues,
analysis of how the family fits together as a enabling strategies to be modified as new
system is described as functional analysis by information is gathered. The therapist is
behavioral therapists. It has much in com- constantly addressing his or her own prob-
mon with the systemic analysis of ap- lem of "How can I assist this family to con-
proaches based on systems theory. duct their own problem-solving functions
The third step involves observation of the more efficiently?"
family having a problem-solving discussion.
Behavioral Family Therapy for Schizophrenia 173
Treatment Program
The most important component of the tre- continuing drug treatment that is carefully
atment program is the behavioral analysis. monitored throughout. Index patients play
The initial and continuous pinpointing of a crucial role in this education. They are en-
specific deficits of family problem solving couraged to describe their own experiences
enables the therapist to assist the family to of schizophrenia and its management to
achieve gradually more fluent strategies for their families. Usually, this is the first oc-
coping with the wide variety of difficulties casion on which the nature of the patient's
they encounter, while at the same time con- symptoms has been discussed among the
tinuing to promote their personal life goals. family. The patient assumes the "expert"
Many families show considerable compe- role, although at times other family mem-
tence in problem solving, but through a lack bers may report similar episodes of schizo-
of understanding of the nature of schizo- phrenic symptoms in the past or even the
phrenia may seek solutions that provoke present. These sessions are delayed until
excessive stress for the index patient. Other the index patient is stabilized after an acute
families may have difficulties conducting a episode and is usually able to discuss his ex-
calm discussion within their family group. periences in an objective manner.
One person may assume dictatorial control A questionnaire is administered before
and prevent the flow of ideas and sugges- and after these initial sessions to assess the
tions from others; another may not listen to amount of information acquired and to note
what others are saying; in many cases, fam- areas where further education may be ne-
ilies do not sit down in a relaxed setting, cessary. Prior to this education, half of all
free from distractions to discuss important patients and family members knew the di-
issues; still other families who reach agree- agnosis of the patient's condition; after-
ment on what appears to be the optimal so- ward, 95% agreed with the primary diagno-
lution to resolving a problem fail to imple- sis of schizophrenia. A 50% increase in
ment that solution owing to inadequate scores on a multiple-choice questionnaire
planning. There are no familial defects that about schizophrenia has been observed
are specific to schizophrenia. However, the consistently (McGill, Falloon, Boyd, and
unusual nature of the disorder and the Wood-Siverio, 1983).
stress that ensues for patients and their
caregivers tend to provoke inefficiencies of
Communication Training
problem solving.
The major interventions employed in the At times of crisis, ineffective patterns of
behavioral family therapy program can be communication substantially impede cop-
divided into four broad categories: ing efforts and contribute to the stress that
1. Education about schizophrenia may trigger exacerbations of schizophrenia.
2. Communication skills training Effective communication is the basis for ef-
3. Problem-solving skills training ficient problem solving. The major com-
4. Behavioral strategies for specific prob- ponents of family communication that are
lems assessed involve the ability to listen em-
pathically to one another when discussing
problem issues, mutual communication of
Education About Schizophrenia
positive and negative feelings, and making
Although the mutual sharing of information constructive requests for behavior change.
about the nature, course, and treatment of The nonverbal and verbal components of
schizophrenia is a continuous process, two interpersonal communication are addres-
sessions at the onset of family therapy are sed, particularly where major deficits
devoted to discussion about the diagnosis, detract from the clarity of such expression.
etiology, management, course, and drug Improved communication is shaped
and psychosocial treatment of the disorder. through skills-training procedures, where-
These initial sessions provide a rationale for by brief segments of interaction are re-
the subsequent family therapy and for the hearsed repeatedly with instructions,
174 I. R. H. Falloon
modeling, social reinforcement, and per- 2. List Alternative Solutions. Once the
formance feedback from the therapist and problem has been specified, a brain-storm-
family members. Homework assignments ing approach is used to generate a list of po-
are employed so that family members con- tential solutions. Discussion about the rela-
tinue to practice these skills outside the tive merits of each solution is postponed,
therapy sessions. and both "good" and "bad" ideas are re-
No specific attempts are made to prevent corded. Reticent family members are en-
family members from expressing criticism, couraged to express their thoughts, and
hostility, rejection, or overinvolved com- every idea is acknowledged by adding it to
munication in their discussions. These pat- the list.
terns of expression, directed toward the in- 3. Discuss Merits of Each Solution. Each
dex patient, have been considered predic- solution is discussed in tum. The advan-
tive of symptom exacerbations (Vaughn tages and disadvantages of each are high-
and Leff, 1976b). Nevertheless, effective lighted.
training of modes of communicating posi- 4. Choose the Optimal Solution. The fam-
tive and negative feelings is likely to reduce ily chooses that solution (or combination of
the frequency with which these potentially solutions) that best fits the needs of the
destructive comments are made. Families problem and the resources of the family.
are encouraged to express their feelings of 5. Plan How to Implement the Solution.
anger, frustration, and guilt within a con- Detailed plans are drawn up to map out the
structive problem-solving framework. In steps through which the solution will be im-
this way, their negative expressions become plemented. Strategies for ensuring that the
the initial steps in identifying and resolving solution is implemented smoothly are de-
difficult problems, thereby relieving stress vised. Major roadblocks are anticipated,
in the family. and ways of coping with these and other im-
portant consequences are discussed. At
Problem-Solving Training
times, families may rehearse the steps
among themselves in a dry run; often
Families are encouraged to adopt a struc- merely talking through the procedures step-
tured approach to their problem-solving by-step is sufficient.
discussions. This involves arranging specific 6. Review All Efforts. Any genuine at-
times when the whole family can meet, free tempt to implement the plan is acknowl-
of distractions, to discuss important issues. edged and praised, even if a successful out-
The frequency of such family meetings, come was not achieved. The family is en-
their duration, and the choice of topic for couraged to review their efforts and to use
discussion is left to the discretion of the all knowledge gained to construct a more
family. However, they are advised to meet effective plan. The notion that successful
at least once a week, to limit the time spent, problem solving requires persistent and re-
and to choose relatively straightforward peated efforts is clearly instilled.
problem issues for their initial meetings. The therapy sessions enable families to
The family therapy sessions examine the practice their problem solving under the
progress of their family discussions and pro- supportive guidance of the therapist. Initi-
vide a workshop for enhancing their ef- ally, and at times of crisis, he or she may
fectiveness. A six-step model of problem need to provide clear direction for the fami-
solving is advocated as a guide for the fami- ly. Guidesheets that list all the steps of
ly meetings. The six steps include: problem solving are used during the ses-
1. Identify a Specific Problem. This step sions and in family discussions at home.
entails active listening to each person's de- One family member "chairs" the discus-
scription of the problem, seeking clarifica- sion, recording notes on the sheets of each
tion when necessary, and avoiding giving problem-solving step. As soon as the family
premature advice or reassurance. The aim begins to master the approach, therapist
is to be able to specify the problem in clear involvement is withdrawn.
operational terms that are readily under-
stood by all family members.
Behavioral Family Therapy for Schizophrenia 175
Behavioral Strategies for Specific Problems setting, and skill training.
The burden of management of severe,
Few families have an adequate repertoire of persistently handicapped individuals can be
coping behavior to manage all the problems substantially reduced when families can
that arise in the course of schizophrenia. learn to make effective use of supportive
Although the problem-solving structure persons and agencies in their social net-
helps facilitate creative resolution of diffi- works.
cult problems, there are times when ad- At all times, the therapist remains clearly
ditional professional assistance may be em- aware that his role is that of a facilitator of
ployed. Behavioral strategies that have family problem solving and that the goal of
been validated in research studies to assist therapy is to enhance the family's own ef-
with symptoms of anxiety, depression, ob- forts in the most efficient manner possible.
sessive-compulsive disorders, persistent de- Thus, additional behavioral strategies are
lusions or hallucinations, medication com- not introduced until the families have failed
pliance, or enhancing social and sexual inter- to achieve a satisfactory outcome with their
action are taught within the family prob- own attempted strategies.
lem-solving context. In addition to teaching A detailed manual of the behavioral
methods of dealing more efficiently with family therapy methods that have been de-
symptomatic states, families may learn a veloped for the community care of schizo-
broad range of general management skills, phrenia are provided in Family Care of
such as operant reinforcement strategies, Schizophrenia (Falloon, Boyd, and McGill,
contingency contracting, role playing limit 1984).
Results
Thirty-six patients (18 in each condition) exacerbations of psychopathology in each
completed the initial 9 months of intensive treatment condition during the first 9
management. In a few cases, pharmaco- months of management: a total of 40 epi-
therapy was not optimal for periods, but in sodes in the family condition and 43 with in-
every case this issue was resolved, obviating dividual therapy. However, of the 18 epi-
the need for withdrawal of cases from the sodes of schizophrenia experienced with
data analysis. family management only, 3 were consider-
ed of major significance. Family cases had
10 further major episodes of nonschizo-
Clinical Morbidity
phrenic symptoms, thereby totaling 13
Patients experienced a similar number of major exacerbations. This contrasted with
Behavioral Family Therapy for Schizophrenia 177
i
130 DAYS
80
60
40
20
Fig. 1. Exacerbations of all symp-
toms (0-9 months).
Individual Family
management management
29 major episodes in the individual condi- parison between the coefficients of varia-
tion, 21 of which involved florid schizophre- tion of the total BPRS scores of each patient
nia . Furthermore , the duration ofthe major over the first 9 months. Family cases sho-
episodes that occurred in the family mana- wed significantly lower coefficients of varia-
gement averaged less than half that of indi- tion than individual cases (P < 0.009).
vidual management: 30 days vs 69. To date, the focus of our assessment has
Figure 1 summarizes the differences in been on florid symptoms. It is possible that
psychopathology between the two condi- the lowered morbidity associated with fam-
tions. Individual management maintained ily management was accomplished at the
symptom stability about half the time , expense of an increase in the deficit , or neg-
whereas family management cases remain- ative, symptoms of schizophrenia. This did
ed stable for about 80% of the time. These not appear to occur. Indeed, there was a
trends were maintained during the less in- trend for deficit symptoms to be reduced
tensive follow-up phase. more with family management. The BPRS
These clinical observations were sup- "withdrawal" factor, which was comprised
ported by rating scale data provided by of the items "motor retardation," "blunted
blind raters and subjected to a repeated affect," "emotional withdrawal," and
measures analysis of covariance. Monthly "grandiosity" (scaled negatively), favored
serial ratings of each patient's specific schiz- family management (P < 0.09) .
ophrenic target symptoms were signif- Qualitative blind ratings of psycho-
icantly lower for family management pathology using the PSE interview showed
(P < 0.003) throughout the 24 months (see no differences in the neurotic symptoms in
Figure 1). A similar trend was observed for the two conditions. At 9 months, ten (56%)
the BPRS "schizophrenic thought" factor of the family-managed cases were in full re-
that combined ratings of thought disturb- mission from schizophrenic compared to
ance, delusions , and hallucinations three (17%) of the individual group. At 2
(P < 0.04). The greater stability with fami- years, 12 (67%) of the family cases showed
ly management was supported by a com- no evidence of schizophrenia, with 9 (50%)
178 I. R. H. Falloon
free from any psychiatric symptoms. In con- tional performance; individual manage-
trast, 14 (83%) of the individual cases sho- ment succeeded in maintaining previous
wed persistence of schizophrenic or para- levels of functioning.
noid symptoms. The results of rating scales of social func-
Thus, there was substantial evidence that tioning showed a similar pattern, although
family management was associated with in- some deterioration of social adjustment was
creased clinical stability related to all evident during the first 9 months of individ-
sources of psychopathology. Furthermore, ual management (Falloon, McGill, Boyd,
there was a trend toward a gradual reduc- and Pederson, in press b). On the self-
tion of clinical morbidity to the extent that report measure (SAS-SR) (Weissman et
half the patients who received family man- al., 1978), an analysis of covariance, using
agement were free of any signs of mental ill- the base line scores as covariates, greater
ness at the end of 2 years. As a result of this overall social adjustment was reported with
reduction in clinical morbidity, substantial- family management (P < 0.02). Significant
ly less hospital care was required. Over the advantages were seen for the family ap-
2 years, family cases averaged 4 days in the proach on scales of leisure activity (P <
hospital and individual cases 23 days. 0.01), and family relationships (P < 0.04).
Seven items from the SBAS social per-
formance scales were examined (Platt,
Social Morbidity
Weyman, Hirsch, and Hewett, 1980).
The determinants of social functioning are These were derived from blind assessor in-
varied, not all associated with illness fac- terviews with key family members. Figure 2
tors. Both the family and individual thera- summarizes these ratings of social perform-
pies endeavored to enhance the social per- ance as well as relatives' dissatisfaction with
formance of the index patient. This was at- the impairment they observed. Small, but
tempted through direct therapist-patient significant, gains in social performance
goal setting and planning in the individual were evident in the first 9 months for family
condition and through teaching the family management cases, whereas some overall
as a whole how to use their problem-solving deterioration in social functioning was evi-
discussions to address similar issues for the dent in half the individually managed pa-
index patient as well as other family mem- tients at 9 months, with improvement
bers. occurring in the 2nd year of the program.
In the initial phase of psychosocial treat- An analysis of covariance, using the base
ment, patients with good premorbid social line scores as covariates, showed significant
adjustment and schizophrenia of recent between-group differences on the combin-
onset tended to have less difficulty re- ed social performance score at 9 and 24
establishing work and social activities. months (P < 0.02). The interaction be-
Eight patients (44%) in each management tween the groups over time was not signif-
condition were paid for work during the icant.
first 9 months. All had been working at the The relatives' dissatisfaction with social
onset of their index episode. Over 24 performance tended to parallel their re-
months, family cases were engaged in func- ports of impairment. During the first 9
tionally useful daily activities (i.e., full- or months, family management appeared to
part-time work, sheltered workshops, ed- reduce dissatisfaction in several cases
ucational or training programs) for an aver- where high levels of impairment remained.
age of 12.6 months. This compared with 7.2 This suggested that the family approach
months for individual cases. During the 24 may have assisted in instilling more tolerant
months prior to the study, patients subse- attitudes in the face of persisting handicaps.
quently assigned to family management had Individual management relatives tended
been occupied in similar constructive activ- toward less tolerant attitudes. The com-
ity for 7.0 months, and those assigned to in- bined dissatisfaction ratings over the 24
dividual management averaged 7.4 months. months significantly favored family man-
Family management was, therefore, as- agement (P < 0.0002). It was possible that
sociated with a substantial increase in func- more tolerant attitudes accounted for re-
Behavioral Family Therapy for Schizophrenia 179
• f l .·· ·
% Family management Individual management
impairment dissatisfaction
100: fimljPairm*ent dissatisfaction
Household 5
tasks
...:;:;:;:;
~... ;:;:;:;:
.. ....
,
~~~~~ ~----~~~~~
o 9 mo 0 9 mo 0 9 mo o 9 mo
100~
oil •
Leisure
activity 50 *
o 9 mo o 9 mo o 9 mo o 9 mo
Work/study
activity
o 9 mo o 9 mo o 9 mo o 9 mo
Decision
making
.u:=.-**
o 9 mo
-----Lt.~~_
0 9 mo
I
0 9 mo
Friendliness/
affection
Everyday
conversation
.~'~I
o 9 mo o 9 mo o 9 mo
100 ~
ti
Relationships ~ ......
outside family s:~
....
o 9 mo o 9 mo o 9 mo o 9 mo
indicates proportion of family-treated patients significantly less
than individually treated, p < .01
* indicates p < .05, Fisher's Exact Test
Fig. 2. Social role impairment and parental dissatisfaction with index patients' performance.
180 I. R. H. Falloon
duced reporting of social impairment. The ysis of covariance, using the base line scores
consistency of clinician, patient, and rela- as covariates, supported the superiority of
tive reports makes this unlikely, as well as the family approach (P < 0.0005).
the fact that the relatives reported continu- Benefits in terms of reductions in the clin-
ing impairment in those same areas of func- ical and social morbidity of family members
tioning where their dissatisfaction had be- other than the index patient were more dif-
come minimal. Therefore, despite the dif- ficult to demonstrate. Although a few fami-
ficulties in assessing social functioning, ly members were suffering from significant
there appeared to be good evidence for the levels of morbidity at base line, the overall
superiority of family management in reduc- levels of distress and burden did not appear
ing the social morbidity associated with to induce measurable impairments in the
schizophrenia. majority of family members. In those family
members where notable morbidity was evi-
dent, family therapy appeared more bene-
Family Morbidity
ficial. Consistent with the trend toward
We have already noted that family toler- slightly increased morbidity for individual
ance toward social deviance may have been management at 9 months, more family
increased by the family approach. Further members in this condition had significant
evidence for benefits to the family members impairment at this point.
who received behavioral family therapy in- It is important to note again that behav-
cluded significant reduction' in the distress ioral family therapy does not aim primarily
they expressed toward the patients' endur- to reduce clinical morbidity; rather, the fo-
ing clinical and social morbidity and reduc- cus is on achievement of positive functional
tion in the overall burden they associated changes. The scales used to assess change in
with having the index patient living in the this study were restricted to measuring im-
household (Falloon, Doane, and Pederson, paired functioning. As a result, positive
in press c). Figure 3 summarizes the functional goals that were achieved in the
changes in family burden in both manage- lives of our patients and families were less
ment conditions. A repeated measures anal- evident in the rating scale data. Approxi-
100 %
Family management
50
o L..-_KU.
Baseline 9 Months 24 Months
100
Individual management
I!?
.!l1
(5
"0
"0
I/)
"0
C
tOO
'":>
I/)
=
0
.!;
I/)
1ii
0
u
10
8
Q)
Cil 7
u
en
Ol
c: 6
'0.
0
()
5
Months
o Individual treatment
• Family treatment
Behavioral Family Therapy for Schizophrenia 183
to attribute the added benefits associated bidity in individual management cases.
with family management to any specific fac- It was tentatively concluded that the
tor. However, detailed data collected dur- major source of the increased efficacy of
ing the course of the study enabled us to family management probably resided in the
consider the probable effects of a number of behavioral family therapy component. Spe-
potential factors on the outcome (Falloon, cific changes resulted from the family edu-
1985). cation (McGill et al., 1983) and coummuni-
First, there was little support for the pro- cation and problem-solving training
position that random assignment had pro- (Doane, Falloon, Goldstein, and Mintz,
duced a bias that favored family man- 1985) that were the core ingredients of
agement. The two conditions were well behavioral family therapy. The coping ef-
matched on prognostic factors. Family ficiency of the family unit was specifically
management patients tended to comply enhanced by the behavioral family therapy.
more readily with medication, but skillful Figure 5 shows a highly significant linear in-
deployment of depot preparations and pro- crease in the effectivieness of the family
grams to improve adherence would seem to unit to resolve the wide range of stressful
have counteracted the potential clinical situations with which they were faced over
morbidity that may have accrued from in- the three trimesters of the intensive phase
adequate pharmacotherapy. Overall there of therapy. No such change in coping was
was a tendency for family cases to ingest evident for family units in the individual
lower amounts of neuroleptic medication condition. This increase in coping remained
than those receiving individual manage- stable after the intensive phase of behav-
ment. The impact of life events that were ioral family therapy had been completed.
not clearly associated with the patient's This improved ability to resolve stress while
condition appeared similar in both condi- achieving functional goals was attributed to
tions. Therapists favored employing family the behavioral family therapy. Further dis-
management in general, but when faced cussion of the process through which ef-
with specific patients and their families, fectiveness of the family therapy appeared
showed no differences in their attitudes to- to have been mediated is provided in Chap.
ward the patient and his assigned form of 15.
management. Conducting family therapy We have concluded that a family man-
sessions in the home on a regular basis con- agement approach that combines optimal
tributed to the very efficient delivery of this pharmacotherapy with comprehensive care
treatment, but rescheduling of missed ap- management, family education, and behav-
pointments and home sessions when neces- ioral family therapy is a cost-effective
sary enabled both conditions to receive a method of producing sustained reductions
similar amount of scheduled therapy. in the clinical, social, and family morbidity
Indeed, extra therapy time and effort was associated with schizophrenia.
required to prevent clinical and social mor-
References
Anderson, C. M., Hogarty, G. E., and Reiss, D. of Geneal Psychiatry, 42, 34-42.
J. (1980). Family treatment of adult schizo- Falloon, I. R. H. (ed.) (1985). Family manage-
phrenic patients: A psycho educational ap- ment of schizophrenia: Clinical, social, family
proach. Schizophrenic Bulletin, 6, 490-505. and economic benefits. Baltimore: Johns Hop-
Cardin, V., McGill, C. W., and Falloon, I. R. H. kins University Press.
(1985). An economic analysis: Costs, benefits, Falloon, I. R. H., Boyd, J. L., and McGill, C. W.
and effectiveness. In Falloon, I. R. H. (ed.), (1984). Family care for schizophrenia: A prob-
Family management of schizophrenia: Clinical, lem-solving treatment for mental illness. New
social, family and economic benefits. Balti- York: Guilford Press.
more: Johns Hopkins University Press. Falloon, I. R. H., Boyd, J. L., McGill, C. W.,
Doane, J. A., Falloon, J. R. H., Goldstein, M. J. Razani, J., Moss, H. B., and Gilderman, A. M.
and Mintz, J. (1985). Parental affective style (1982). Family management in the prevention
and the treatment of schizophrenia. Archives of exacerbations of schizophrenia: A control-
184 I. R. H. Falloon
led study. New England Journal of Medicine, McGill, C. W., Falloon, I. R. H., Boyd, J. L.,
306,1437-1440. and Wood-Siverio, C. (1983). Family educa-
Falloon, I. R. H., Boyd, J. L., McGill, C. W., tional intervention in the treatment of schizo-
Williamson, M., Razani, J., Moss, H. B., Gil- phrenia. Hospital and Community Psychiatry,
derman, A. M., and Simpson, G. M. (in press 34, 934-938.
a). Family versus individual management in the Platt, S., Weyman, A., Hirsch, S., and Hewett,
prevention of morbidity of schizophrenia. I. S. (1980). The social behaviour assessment
Clinical outcome of a two-year longitudinal schedule (SBAS): Rationale, contents, scoring
study. Archives of General Psychiatry. and reliability of a new -intervention schedule.
Falloon, I. R. H., McGill, C. W., Boyd, J. L., Social Psychiatry, 15, 43-55.
and Pederson, J. (in press b). Family versus Selvini-Palazzoli, M., Ceechin, A., Prata, G.,
individual management in the prevention of and Boscolo, L. (1978). Paradox and counter-
morbidity of schizophrenia: II. Social outcome paradox. New York: Jason Aronson.
of a two-year longitudinal study. Psychological Vaughn, C. E., and Leff, J. P. (1976a). Theinflu-
Medicine. ence of family and social factors on the course
Falloon, I. R. H., Doane, J. A., and Pederson, J. of psychiatric illness: A comparison of schizo-
(in press c). Family versus individual manage- phrenic and depressed neurotic patients. Brit-
ment in the prevention of morbidity of schizo- ish Journal of Psychiatry, 129, 125-137.
phrenia: III. The adjustment of the family unit. Vaughn, C. E., and Leff, J. P. (1976b). The
Psychological Medicine. measurement of expressed emotion in families
Fromm-Reichmann, F. (1948). Notes on the de- of psychiatric patients. British Journal of Social
velopment of treatment of schizophrenics by and Clinical Psychology, 15, 157-165.
psychoanalytic psychotherapy. Psychiatry, 11, Weissman, M. M., Prusoff, B. A., Thompson,
263-273. W. D., Harding, P. S., Myers, J. K. (1978). So-
Jackson, D. D., and Weakland, J. H. (1961). cial adjustment by self-report in a community
Conjoint family therapy: Some consideration sample and in psychiatric outpatients. Journal
on theory, technique, and results. Psychiatry, of Nervous and Mental Disease, 166,317-326.
24 (2) (Supplement), 30-35. Wing, J. K., Cooper, J. E., and Sartorius, N.
Leff, J., Kuipers, L., Berkowitz, R., Eberlein- (1974). The measurement and classification of
Vries, R., and Sturgeon, D. (1982). A control- psychiatric symptoms. London: Cambridge
led trial of social intervention in the families of University Press.
schizophrenic patients. British Journal of Wynne, L. C., Ryckoff, I., Day, J., and Hirsch,
Psychiatry, 141, 121-134. S. (1958). Pseudo-mutuality in the family rela-
Lidz, T., Fleck, S., and Cornelison, A. (1965). tions of schizophrenics. Psychiatry, 21,
Schizophrenia and the family. New York: In- 205-220.
ternational Universities Press.
15. Impact of Family Intervention Programs on
Family Communication and the Short-Term
Course of Schizophrenia
M. J. Goldstein and A. M. Strachan
Introduction
Recent interest in the role of the family in Now, if there are stress-producing as-
the course of schizophrenia has focused on spects of the family environment which in-
aspects of the family environment which in- crease the likelihood of a relapse, then inter-
fluence the short-term course of the disor- vention programs designed to modify these
der once an episode of schizophrenia has aspects of the family environment should
occurred. One research strategy has been to produce a more favorable course. This has
measure aspects of the family environment been the rationale underlying four major
and then follow the natural course of the pa- studies, three of which have been com-
tient's psychiatric and social functioning. pleted (Chaps. 13,14; Goldstein, Rodnick,
This strategy has successfully demonstrated Evans, May, and Steinberg, 198) and one
that relatives' expressed emotion (EE) which is close to completion (Chap. 12).
about the patient is predictive of relapse in This chapter will provide a brief overview
both British and American samples (Chaps. of the outcome of these four studies and will
2, 8). Further, it has been demonstrated then describe in depth the impact of one in-
that this measure of emotional attitudes re- tervention program on family interactional
lates to direct observational measures of variables hypothesized to be important in
communication with the patient (Chap. 4). indexing family status: affective communi-
cation, problem solving, and coping.
Family intervention
[]:ID No family intervention
18
16
14
o
OIl
~ 14
.,
s::
.0 10
~
"8 16
u
~ 6
4
Fig. 2. Total number of critical and intrusive
statements at 3 months post-test, by therapy 2
group (adjusted means).
Family Individual
F = 8.052 . dl 1/29. therapy therapy
P< 0.008
For treatment group
188 M. J . Goldstein and A. M. Strachan
24
20
18
rn ~ Pre-therapy assessment
0
.;::; 16 _ 3 Month post-the rapy assessment
«l
.r::
<Il
.D 14
"0
<Il
"0
0
12
(.)
(f)
« 10
'0
Q; 8
.D
E
;:)
c:
6
(ij
(5 4
I-
the parents in the family or individual treat- tween the reduction of negative affective
ment groups was valid for both types of fam- communication in a parent, or parents, and
ilies. Figure 3 gives pre- and post-AS data the likelihood of relapse in the patient off-
for both types of family structures by treat- spring. To deal with these two questions,
ment condition. We see that there is a com- the 33 families were divided into three
parable reduction in the sum of criticisms groups based on the patterns of pre- and
and intrusions for both types of family post-AS scores. Since the British work on
structures in the family treatment condi- EE treats criticism and overinvolvement as
tion. Interestingly, while there was little or independent dimensions in defining EE sta-
no change in the level of negative AS state- tus, we considered the rate of change in crit-
ments for single parents in the individual icism separate from the rate of change in in-
treatment condition, there are suggestions trusiveness. Families were thus classified
of a worsening affective climate in the dual- into three categories: (1) dual increase, in
parent families when only the patient is which both criticism and intrusiveness in-
treated. This was quite intriguing, but un- creased from pre- to posttest, (2) dual de-
expected, as we had anticipated that the crease, in which both declined during the
single parents, because of their limited same period, and (3) a mixed group in
marital support system, might deteriorate which one attribute increased while the
more without family treatment. other decreased. Figure 4 presents the fre-
The pattern of group means suggests the quency of each type of family change pat-
Falloon family management approach does tern by treatment group, and it also pre-
indeed reduce the average level of negative sents the number of relapse cases that oc-
affective communication in parents of curred in each of these pattern-based cate-
schizophrenics. However, an average does gory groups. First, we see that the dual in-
not tell us how many families reduced this crease pattern is found in half of the individ-
behavior in each treatment condition nor ual therapy families but only rarely appears
does it establish a precise association be- in the family therapy group. Conversely,
Impact of Family Intervention Program 189
Family therapy Individual therapy
(n = 17) (n = 16)
10
(/)
Q)
6 o No relapse
(/) • Relapse
C1:l
0 4
0
01 MX 00 01 MX 00
Change in criticism/intrusiveness
Fig. 4. Patterns of change in AS in individual and family therapy. DI = dual increase; MX = mixed;
DD = dual decrease.
the dual decrease pattern is prominent in cently been reported by Doane et a1. (1985)
the family-treated cases, but less frequent which involved the ratings of coping effec-
in the individual therapy condition. The fre- tiveness alluded to earlier. Doane et a1.
quency of the mixed pattern does not vary classified families at the 3-month assess-
by treatment groups. Thus, there is a clear ment as relatively benign or negative in AS,
trend for reduction in one or both forms of on the basis of parental behavior in the in-
the negative AS behaviors in the family tre- teraction task. Her classification was based
atment condition. on whether the parent(s) reduced the num-
All but one of the relapses occurred in the ber of harshly critical remarks (personal cri-
individual therapy condition, and all but ticisms, guilt-inducing remarks, or critical
one occurred in the dual increase or mixed intrusions) or reduced the number of in-
groups. The probability of relapse for indi- trusions below a previously determined cut-
vidually treated patients in or of these two ting score of six. Within the family therapy
groups is 67% compared with 25% for the condition, negative AS status was associat-
dual decrease group. These data show that ed with lower coping than the benign AS
88% of families in family therapy have a re- families at the 3-month point. However,
duction in one or both dimensions of AS in after 3 more months of family therapy, the
contrast to 50% of those in the individual differences between the two AS groups had
therapy condition. Increases in AS are as- disappeared and both, in fact, showed sig-
sociated with relapse in that condition as nificantly higher levels of coping than either
well. What is puzzling is that there are some AS group in the individual therapy condi-
cases in the family therapy condition who tion, who had in fact deteriorated in coping.
show the dual increase pattern (n = 2) or Thus, while there are some families who
the mixed pattern (n = 6) who did not re- had not reduced their negative AS by 3
lapse. Of course, this reassessment of the months, they did show improvement with
families occurred after only 3 months of sustained family therapy, and this improve-
family therapy, and it is possible that with ment in coping is associated with a signifi-
sustained therapeutic contacts over the sub- cantly lower rate of patient relapse than was
sequent 6 months, changes in the affective found in the individual therapy condition.
climate of these families did occur which In the latter condition, there seemed to be
prevented relapse. little change in family coping effectiveness
Data supporting this hypothesis have re- following the 3-months assessment.
190 M. J. Goldstein and A. M. Strachan
Discussion
The various studies summarized in this form of problem solving takes the place of
chapter indicate that the affective climate of the negative interaction patterns of criti-
the family with a schizophrenic young adult cism, blaming, and intrusiveness into the
offspring relates to the short-term course of inner state of the patient. When a large re-
the disorder. Further, when family-based duction in the negative AS behaviors (in the
interventions are associated with a longer form of redcutions in both criticism and
period of community tenure for the patient, intrusiveness) has occurred, a major shift in
parallel reductions in this negative affective this more affectively neutral, task-centered
climate are noted in direct observations of behavior is observed; the reverse is noted
family behavior. The optimum results were when heightened levels of both forms of AS
found when both components of the AS are evident. These data suggest a marked
system, criticism and intrusiveness, were reciprocity between uncontrolled negative
reduced in frequency from pre- to a 3- affective expression focused upon the pa-
month posttest assessment, although be- tient and more controlled, cognitive form of
nefits were observed when only one com- behavior focused upon common family
ponent was attenuated. problems. Since we have only two points in
Whenever one type of family behavior is the Falloon study where direct interaction
reduced in frequency, it naturally raises the data were obtained, we cannot speak to the
question of what characterizes the new pat- sequential linkage between these two di-
tern of family transactions. A key objective mensions of family behavior. Does family-
of the Falloon et al. study was to train family based intervention first inhibit negative af-
members in a defined set of strategies for fective expression, thereby permitting the
dealing with problems inside and outside of acquisition of problem-solving skills? Or,
the family. A coding system was developed does the early acquisition of problem-solving
by Doane et al. (1985) for recording in- skills simply replace negative affective ex-
stances in the direct family interaction tasks pression without any specific instructions to
where family members utilized these re- limit or inhibit these behaviors? Further
commended problem-solving strategies studies with repeated observation of the
(PSS). When pre- and 3-month direct in- family therapy process are needed to tease
teraction tasks data were contrasted in the apart these issues - issues that are critical to
number of PSS behaviors expressed, there understand if were are to plan more effective
was a highly significant difference between programs for optimizing family change.
treatment conditions at 3 months favoring An interesting finding was that family
the family-treated group (adjusted mean coping responses to external life events im-
FT = 24.59; adjusted mean IT = 10.39, F = proved over time in the family therapy con-
6.60, P < 0.02). Also, when the pattern of dition, particularly in the families with
change in AS presented in Figure 4 was negative AS profiles. Unfortunately, the
examined for PSS change levels, sharp dif- measure of coping was very global, and thus
ferences were found between the dual de- it is not known whether the improvement in
crease groups in family therapy and dual in- coping represents changes in behavioral,
crease group in individual therapy in the 3- cognitive, or emotional responses. Hatfield
month data (mean PSS for dual decrease FT (1981) studied coping in the families of the
= +20.0; mean dual increase IT = -0.20). mentally ill and found that coping varied
This means that in the former group there on a number of dimensions: emotional
were 20 more instances of PSS behavior mastery, cognitive skill in understanding
than was evident at pretest, while in the lat- the illness and learning management strate-
ter there was virtually no change from base gies, and the extent to which relatives main-
line. The remaining AS change groups sho- tained outlets for their own personal needs.
wed slight positive changes in scores that An important avenue of research would be
were similar in the two treatment condi- to understand the development of family
tions. member's abilities to cope over time and
These data suggest that a task-centered the interaction with their style of emotional
Impact of Family Intervention Program 191
expression. interventions typically cease or patients are
Much of this chapter has emphasized the transferred to some other clinical unit or
impact of a combined program of phar- service. What happens to those patients and
maco- and family therapy on relapse rate their families at this point? Do they start to
over a 9-month to I-year period after dis- relapse rather rapidly or do they continue to
charge for an episode of schizophrenia. It is hold the gains observed during the "offi-
obviously an important criterion for a suc- cial" treatment period? Evidence concern-
cessful maintenance program, but relapse ing maintenance or deterioration in both
prevention is a minimal criterion for a treat- the patient and intrafamilial relationships in
ment program. Can a family intervention general would be useful. If there is little re-
program extend beyond this minimal ob- tention of the gains observed during the
jective to facilitate improved social role controlled trials, it does not imply that these
functioning? The data here are far from drug and family programs are without
complete. Findings from the Falloon et al. value. Instead, they could suggest that the
study do suggest that significantly greater treatment of schizophrenia requires a type
improvements in social role functioning of longer-term commitment than most re-
were observed in the family than in the indi- search studies can typically guarantee.
vidually treated group. Also, the recent re- One final issue, because the emphasis of
port by Doane et al. (1985) indicates that a this chapter has been upon the family of the
reduction in negative AS from pre- to 3- schizophrenic and family-oriented treat-
month assessment was associated with high- ment programs, we have not emphasized
er levels of social functioning than when this issues concerning the long-term pharmaco-
was not the case. Also, Anderson et al. therapy of the patient. We should never for-
(this volume) report improvements in social get that all of the successful family pro-
role functioning when families were in the grams are built upon a foundation of regular
family therapy condition. Thus, it appears and continuous pharmacotherapy. How-
that modifications of the affective climate ever, the successful addition of family-
of the family achieves more than relapse based intervention programs to regular
prevention and is associated with greater pharmacotherapy raises the question of
social improvement as well. Despite these whether a potent social therapy permits
encouraging findings, it is still not clear alteration in the strategy of drug treatment
what level of social improvement is possible in terms of dose level and pattern of treat-
when such a multimodal program is con- ment. Given the evidence that a com-
tinued beyond the 9-month point of active prehensive family intervention program
treatment used in the Leff et al. and Falloon produces some degree of stabilization of the
et al. programs. Certainly, the optimistic stress level in the social environment, we
results to date warrant continued efforts to can now consider whether this stabilization
test the limits of efficacy of such programs. permits the use of lower dose levels of phe-
Along these lines, it would be very help- nothiazine medication or even more radical
ful to gather data concerning the long-term strategies, such as intermittent or targeted
impact of these family-focused programs use of medication. An ironic side effect of
after they officially cease. Most of the con- an effective family program may be that it
trolled trials described in this paper have permits greater latitude for experi-
offered drug and family interventions for mentation in the complementary area of
roughly half of their sample for a fixed time psychopharmacology.
period. At the end of the time period, these
References
Doane, 1. A., Falloon, 1. R. H., Goldstein, M. Doane, 1. A., Goldstein, M. 1., Miklowitz, D. 1.,
1., and Mintz, 1. (1985). Parental affective style and Falloon, 1. R. H. (in press). The impact of
and the treatment of schizophrenia: Predicting individual and family treatment on the affective
course of illness and social functioning. Ar- climate of families of schizophrenics. British
chives of General Psychiatry, 42, 34-42. 10urnal of Psychiatry.
192 M. J. Goldstein and A. M. Strachan
Goldstein, M. J., Rodnick, E. H., Evans, J. R., study. Journal of Psychiatric Treatment and
May, P. R. A., and Steinberg, M. R. (1978). Evaluation, 3. 11-19.
Drug and family therapy in the aftercare of Vaughn, C. E., and Leff, J. P. (1976). The influ-
acute schizophrenic. Archives of General ence of family and social factors on the course
Psychiatry, 35,1169-1177. of psychiatric illness: A comparison of schizo-
Hatfield, A. B. (1981). Coping effectiveness in phrenic and depressed neurotic patients. Brit-
families of the mentally ill: An exploratory ish Journal of Psychiatry, 129, 125 -137.
16. The Psychosocial Program of Treatment
of Schizophrenic Patients in the
Crakow Psychiatric Clinic
B. Barbaro, A. Cechnicki, A. Szymusik, K. Zawadzka, and J. Zadecki
Final Remarks
Psychosocial models have begun to play an ble onte to predict which patient will profit
increasingly important part in the treatment from a rehabilitation program (Klar, Fran-
of schizophrenia (Stierlin, Wynne, and Wir- ces, and Clarkin, 1982). It is a positive de-
sching, 1983). The model described here pro- velopment that various systems of therapy
vides more intensive treatment and re- take into account the patient's individual
habilitation than is possible in traditional needs. This permits therapists to compare
ambulatory treatment. Through its many their experiences and the results of research
links, such as the day hospital or the hostel, (Anthony, Cohen, and Ray, 1978; Katsch-
high expectations for change are rein- nig, 1985). The fairly homogeneous popula-
forced. tion of our patients in terms of age, the pre-
The greatest dilemma confronting the cli- cisely determined diagnostic criteria, and
nician preparing such a social treatment the specific description of various forms of
program is whether the patient can profit therapy used in our system permit further
from a less intensive ambulatory treatment, longitudinal research to evaluate both the
such as traditional individual psychothera- total model and the suitability of the various
py and supportive neuroleptic treatment. components for any given patient.
There are not patient attributes which ena-
References
Anthony, W. A., Cohen, M. R., and Ray, V. dology in evaluation of psychiatric treatment.
(1978). The measurement of rehabilitation out- Cambridge: Cambridge University Press.
come. Schizophrenia Bulletin, 4, (3). Kayser, and Mavers, W. (1973). Gruppenarbeit
Balint, M., and Balint, E. (1962). Psychothera- in der Psychiatrie [Group work in psychiatry].
peutische Techniken in der Medizin. Stuttgart: Stuttgart: Thieme.
Klett. Klar, H., Frances, A., and Clarkin, 1. (1982).
Brown, G. W., Birley, J. L. T., and Wing, 1. K. Selection criteria for partial hospitalization.
(1972). The influence of family life on schizo- Hospital and Community Psychiatry, 33,11.
phrenic disorders: A replication. British Jour- Kuipers, L. (1979). Expressed emotion. A
nal of Psychiatry, 121,241-258. review. British Journal of Social and Clinical
Cechnicki, A., Zawadzka, K., Rostworowska, Psychology, 18,237-243.
M., Zadecki, J., and Barbaro, B. (1984). Die Stierlin, H., Wynne, L. C, and Wirching, M.
sozialpsychiatrische Tagesklinik fUr schizo- (Eds.) (1983). Psychosocial intervention in
phreniereagierende Patienten [The Socio- Schizophrenia. An international view. Heidel-
psychiatric day clinic for patients with schizo- berg: Springer.
phrenic reactions]. Paper presented at the Szymusik, A., Cechnicki, A., and Zadecki, J.
XVth Symposium of the DAP, Munich. (1982). Die Entwicklung der Idee der dynami-
Goffman, E. (1961). Asylums. Essays on the schen Psychiatrie in der Psychiatrischen Klinik
social situation of mental patients and other der Medizinischen Akademie in Krakow
inmates. Chicago: Aldine. [Development of the idea of Dynamic Psychia-
Howells, J. G. (1968). Theory and practice of try in the Psychiatry Department of the Aca-
family. Edinburgh: Oliver and Boyd. demy of Medicine in Crakow]. Paper presented
Katschnig, H. (1985). Methods of measuring so- at the XIVth Symposium of the DAP, Munich.
cial adjustment. In T. Helgason (Ed.), Metho-
200 B. Barbaro et al.
Vaughn, C. E., and Leff, J. P. (1976). The influ- phrenic and depressed neurotic patients. Brit-
ence of family and social factors on the course ish Journal of Psychiatry, 129, 125-137.
of psychiatric illness. A comparison of schizo-
Epilogue
Introduction
Schizophrenia is not to be understood as nerable person from stress-related, bio-
psychopathology alone, or as a set of bio- medical determinants of schizophrenic re-
logical impairments or deficits; rather, the lapse. One major source of protection
nature of schizophrenia is to be found in the emerges from studies of the familyenviron-
interfaces among environmental, behav- ment where supportive, tolerant, and
ioral, and biological factors. Some of these understanding relatives who exhibit realis-
factors endure over time and change only tic expectations for social performance
slowly in response to changes in the en- from a schizophrenic member can reduce
vironment. Biobehavorial factors operate relapse to 15% in 9 months following dis-
on the person as vulnerability to episodes of charge from the hospital (Vaughn et aI.,
schizophrenic symptoms when they endure 1982). On the other hand, ambient levels of
through periods of remission as well as re- stress and tension within the family can
lapse. Abnormalities in information pro- negatively affect patients who suffer from
cessing and attention as well as autonomic schizophrenia. When individuals with the
reactivity have been implicated as enduring specific psychobiological vulnerability to
vulnerability factors across illness episodes schizophrenia experience stress and tension
as well as in children at risk for schizophre- from family transactions, relapse or exac-
nia (Nuechterlein and Dawson, 1984). In- erbation of symptoms is made more likely,
adequate learning opportunities during with relapse rates exceeding 50% in the 9
one's developmental years can also lead to months after hospitalization. Family pat-
subsequent, enduring deficits in social and terns of stress are interactional as schizo-
occupational capabilities that may increase phrenic persons also produce stress on their
a person's susceptibility to schizophrenic relatives by virtue of their symptoms and
symptoms. For example, certain schizo- social impairments. This interactional pat-
typal traits have been posited as vulnerabil- tern leads to emotional overinvolvement
ity factors in schizophrenia (Chapman, and excessive criticism from relatives in
Edell, and Chapman, 1980). Furthermore, about two-thirds of Anlgo-American fami-
studies have demonstrated that premorbid lies (Vaughn et aI., 1984). Thus, family
social and occupational deficiencies can interaction processes, both unfavorable
predict subsequent symptomatic status and and supportive, go in both directions and
rehospitalization of schizophrenic patients can affect patients and their relatives in re-
(Strauss and Carpenter, 1981). Enduring verberating cycles.
biobehavioral vulnerabilities interact with Brief cross-sectional views of course and
transient, time-limited stressful life events, outcome seen at anyone point in time in our
longer-term environmental potentiators of assessments and follow-ups of patients with
risk to symptoms, and protective factors schizophrenia can be interpreted from
that operate at the environmental and per- a vulnerability-stress-coping-competence
sonallevels. model. These are really not "outcomes" but
Progress has been made in recent years in rather momentary "snapshots" of how the
identifying factors that can protect a vul- family environment, the social network,
8 ~ Personal vulnerability factors
3~ f3
('1) I-' r-------------~i i
o .
;:;J> Reduced Autonomic
Schizotypal
g..g Dopaminergic available hyperreactivity
personality :;tl
N-= dysfunctions processing to aversive
o :::t_ traits .."
'1:1 '" capacity stimuli
0" O.
.... (")
('1) (")
~
('1)
~-g
f6 Intermediate states Outcomes 3
-g ::l
'"
Personal protectors
=
e.. ~--------~i ~i----------~
Processing Social
q> capacity functioning
Coping overload
Antipsychotic
and
medication
I self-efficacy
Q
* Tonic Schizophrenic
= Prodromal
autonomic psychotic
symptoms
~ Environmental Protectors hyperarousal symptoms
fa
8.5- Family Supportive
OQ problem psychosocial
g. solving interventions Deficient
('1) Occupational
< processing
functioning
:::t_
'" of social stimuli
2:
('1)
'"
[ T Enviro~menital potentiators and ~tressl"'io_r_s__________--,
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....
o emotionally stimulating Stressful
overinvolved social life events
§ family climate environment
;jl
('1)
Case Example
To elucidate the vulnerability-stress-cop- which was supportive, nurturing, warm,
ing-competence model of schizophrenia, and friendly. The staff were helpful to him
we might think of a farm boy, Michael, who and seemed to understand his needs for pri-
at the age of 18 is recruited into military vacy and quiet. They did not expect much
service. He has spent all of this life in a rural from him. He did not have to polish his
and serene pastoral county, without very shoes or make his bed in the morning. He
much contact with people. He went to a received antipsychotic medication and
small school but avoided contact with other slowly but surely his symptoms subsided.
children. Most of his time was spent on the He began to tentatively socialize, and his
slopes of his native mountains, tending level of function returned to its premorbid
sheep and cows. He has poorly developed level.
social skills with peers. His parents were At this point, he was discharged from the
also socially withdrawn and did not provide military hospital and returned to his family
opportunities to learn expressiveness or home. Unfortunately, the protective fac-
intimacy. There was, at the genetic level, a tors provided by the military hospital did
grandfather who spent many years in the not get communicated to Michael's after-
state pychiatric hospital, presumably for a care system. The psychiatrist in the milita-
schizophrenic disorder. ry did not talk to the psychiatrist respons-
At the age of 18, Michael entered military ible for the rural clinic near Michael's home
training. He lived in a barracks full of other nor to Michael's parents. As a result,
young men, most of whom came from lar- Michael returned home to family members
ger cities. They talked openly, fast, and who were baffled and confused about what
loud. He was not used to this active and had happened to him. He looked normal.
stimulating social intercourse and he expe- There were no outward signs of illness. He
rienced difficulty in processing the incoming was taking some pills, which his parents felt
information. He did not know how to make made him sleepy and were a sign of weak-
jokes with his fellow recruits. He did not ness. His parents told him that he did not
know how to brag about his sexual exploits really need to have those pills as long as he
because he did not have any. After several ate his ample farm meals and drank a lot of
stressful weeks of trying vainly to cope with good milk. His parents urged him to again
the rigorous military discipline and peer work on the farm. Their expectations for his
pressure, he experienced confusion in his work capacity were as high as before, if not
thinking and autonomic symptoms of anxie- higher, because they were frustrated and
ty. These prodromal symptoms of psychosis annoyed with him for having failed to com-
were quickly followed by ideas of reference plete his military service.
and then delusions that thoughts were being As the performance demands on the farm
put into his head by his officers. He showed and pressures within the family mounted,
lapses in attending his regular duty, was Michael experienced the return of weird
awake at night, and was brought to the mili- feelings. He felt unreal and became obses-
tary hospital with florid hallucinations and sed with concerns about bodily decay and
delusions where the psychiatrist pronounc- dying. The long-acting antipsychotic med-
ed him as suffering from a schizophrenic ication was slowly metabolized and ex-
disorder. creted, and Michael again developed the
Michael then went into a hospital ward symptoms of schizophrenia.
204 R. P. Liberman
Reference to Figure 1 will enable the rea- tive capacities and social functioning; how-
der to chart the evolution and course of ever, returning home to family members in
Michael's disorder and to identify points of a tense and unsupportive home environ-
departure for therapeutic intervention. The ment led quickly to relapse when the pro-
prototypical patient, Michael, had both tective benefits of medication were with-
genetic and schizotypal personal vulnerabi- drawn.
lity to schizophrenia. As he was exposed to Several entry points for therapeutic inter-
the stressors of leaving home and entering vention present themselves, including fam-
the military, his personal and coping skills ily education and management, mainte-
and environmental support were inade- nance neuroleptic drug therapy, social skills
quate to protect him from the emergence of training, and less demanding vocational
psychotic symptoms. Prodromal symptoms and peer settings. The diagram in Figure 1 is
were associated with autonomic hyper- meant to highlight the reverberating cycles
arousal and cognitive overload and were and interactions among factors influential
precipitated by an overstimulating environ- in the course of schizophrenia. Protective,
ment in the military. potentiating, vulnerability, and stress fac-
The supportive framework of the military tors interact to determine the symptomatic
hospital combined with neuroleptic med- and functional status of a person at anyone
ication temporarily reconstituted his cogni- time.
Table 1. Relapse Criteria Based on the PAS Psychotic Symptom Scale of Delusions, Hallucinations,
and Incoherence
Type I:
If a change from discharge rating occurs on only one of the three scales, a 2-point increase is designated
as a relapse, providing that a maximum severity score of 4 on that scale occurs. Thus, score increases
from 0 to 2 or from 1 to 3 would not be considered a relapse, but an increase from 2 to 4 would be a re-
lapse.
Type II:
A total increase of 3 points on one or more of the three scales is designated a relapse with the caveat
that single-point changes from 0 to 1 are not counted. (Zero represents symptoms absent, while 1 indi-
cates symptoms not clearly pathological. )
208 R. P. Liberman
Table 2. Interrater Reliabilities of the PAS Psychotic Symptom Scales
Table 3. BPRS Scales and Behavioral Anchors Used to Define Various Types of Relapse. Interrater
Reliability is Expressed as Median Intraclass Correlational Coefficients.
Psychotic Relapse
Modular Interventions
Cost constraints in the delivery of mental Medical Center in Los Angeles (Liberman
health service will move our interventions and Foy, 1983). The program focuses on
beyond minimum-maximum strategies to goal setting and problem solving. Modules
modular approaches that specify the ele- are provided for training these skills that a
ments of treatment that are best for certain patient lacks. A module is composed of a
patient needs. We know, for example, that category of skills falling within a major life
neuroleptics seem best for the positive domain and is constructed so that problem-
symptoms of schizophrenia. Workers in solving and interpersonal skills are taught
psychiatric rehabilitation also are develo- simultaneously.
ping methods for remediating specific social Each module is divided into separate skill
deficits through social skills training (Liber- areas with each area having specific behav-
man, Massel, Mosk, and Wong, 1985b). iors that are taught to achieve personal ef-
One example of a modular approach to fectiveness and competence. For example,
training social problem-solving skills to the module that teaches "medication self-
chronic mental patients comes from work at management" contains skill areas on (a)
the UCLA Clinical Research Center for learning about the benefits and side effects
Schizophrenia (Foy, Wallace, and Liber- of medications, (b) acquiring the skills of
man, 1983). Modules have been developed medication self-administration, and (c)
for training a variety of social and indepen- coping with the side effects of medication.
dent living skills, including personal hy- Patients proceed through each module in
giene, conversational skills, use of public sequence, starting with an "introduction"
agencies, job finding, leisure and recrea- that aims to highlight the values and advant-
tion, medication management, and money ages of the module to motivate subsequent
management. The modules are constructed participation. After acquiring requisite
to teach a patient specific functional skills, knowledge and skills in the "training"
to train the patient to solve problems that phase, patients learn how to gather the tan-
may be encountered while attempting to gible and social resources required to put
employ these new skills, and for practicing the skills to use. For example, to negotiate
the skills in vivo. medication side effects or dosage issues
Because most chronic mental patients with the prescribing physician, a patient
suffer from a spectrum of deficits in social must be able to use a telephone to make an
and independent living skills, a comprehen- appointment to see the doctor and find
sive yet modular program for remediating transport to take him to the doctor. After
these deficits has been designed and operat- solving such "resource management prob-
ed at a 500-bed Veterans Administration lems," patients anticipate "outcome prob-
N
I-'
N
(:i
:0
t::
cr'
(1)
Structured 3
Florid symptoms activities Intensive Il>
of schizophrenia psychopharma- ::I
graded
cotherapy
expectations
Specialized
behavior therapy
Sx's remit? token economy Increase dose
eod
social learning
Depot drugs
and
med education
Low dose drugs
0<
mtermittant
supportive, drugs
goal-oriented
psychosocial Ax 0'
drug-free trial
Vocrehab
Social skills
tramlng
Psychosocial rehab
and community support
program
(social prostheses)
Consider
drug-free
trial
Fig. 2. Decision tree for clinical management of schizophrenic disorders: drug and psychosocial
treatment strategies
Copying and Competence 213
lems" which might interfere with the suc- the physician at the appointment. Patients
cessful implementation of the skills in the can enroll in one or more of these modules,
natural environment. Thus, patients learn depending upon the extensiveness of their
how to deal with disappointing events, such deficits and the nature of the goals estab-
as the lateness or unpredicted absence of lished for their treatment.
References
Alevizos, P. N., DeRisi, W. J., Liberman, R. P., Backer, T., Liberman, R. P., and Kuehnel, T. G.
Eckman, T., and Callahan, E. (1978). The de- (1985). Living on the edge: An educational
velopment and application of a method of videotape for helping families cope with chro-
direct observation for program evaluation. nic schizophrenia. Available from Camarillo-
Journal of Applied Behavior Analysis, 11: UCLA Research Center, c/o Training Co-
243-257. ordinator, Box A, Camarillo, CA 93011.
Andreason, N. (1986). Schizophrenia update. In Banzett, L. K., Liberman, R. P. Moore, J. W.,
A. Frances (Ed.) Psychiatry 1986. Washington, and Marshall, B. D. (1984). Long-term follow-
D.C.: American Psychiatric Press. up of the effects of behavior therapy. Hospital
Annon, J. S. (1974). The behavioral treatment of and Community Psychiatry, 35: 277-279.
sexual problems, Honolulu: Enabling Systems, Carpenter, W. T., McGlashin, T. H., and
Inc. Strauss, J. S. (1977). The treatment of acute
Copying and Competence 215
schizophrenia without drugs. American Jour- and Cardin, V. (1985a). Resource book for
nal of Psychiatry, 134: 14-20. psychiatric rehabilitation. Available from
Chapman, L. J., Edell, W. S., and Chapman, J. Camarillo/UCLA Research Center, c/o Train-
P. (1980). Physical, anhedonia perceptual ing Coordinator, Box A, Camarillo, CA 93011.
aberration, and psychosis processes. Schizo- Liberman, R. P., Massel, H. K., Mosk, M. D.,
phrenia Bulletin, 6: 639-653. and Wong, S. E. (1985b). Social skills training
Falloon, I. R. H. (1984). Relapse: A reappraisal for chronic mental patients. Hospital and Com-
of assessment of outcome in schizophrenia. munity Psychiatry, 36: 396-403.
Schizophrenia Bulletin, 10: 293-294. Licht, M. H. (1984). Assessment of client func-
Foy, D. W., Wallace, C. J., and Liberman, R. P. tioning in residential settings. In M. Mirabi
(1983). Advances in social skills training for (Ed.) The Chronically mentally ill: research
chronic mental patients. In R. D. Craig and R. and services. New York: SP Medical and
J. McMahon (Eds.) Advances in Clinical. Scientific Books.
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Maze!. ethological analysis of behavioral change in
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(1977). A standardized psychiatric assessment son and E. Corson (Eds.) Ethology and non-
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Psychiatric Scandanavica, 55: 299-308. York: Pergamon Press.
Liberman, R. P. (1982). Assessment of social Mosher, L. and Keith, S. (1979). Research on the
skills. Schizophrenia Bulletin, 8: 62-84. psychosocial treatment of schizophrenia. Ame-
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ioral programs in institutions and community Nuechterlein, K. H. and Dawson, M. E. (1984).
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velopmental Disabilities, 3: 131-259. ophrenic episodes. Schizophrenia Bulletin,
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(1986). Dissemination and adoption of psycho- Overall, J. E., and Gorham, D. R. (1962). The
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Liberman, R. P., Kuehnel, T. G., Phipps, C. C.,
Subject Index
Acceptance 47, 79, 80, 82, 90 Camberwell Family Interview (CFI) 25. 26,
Acute phase 4 32. 38. 39.44. 51, 52. 59. 60. 61. 63. 73. 74.
- psychotics 111. 112 76.79,80.83.87,94.98,104. 110. 113. 158.
Adherence to medication 119 159,160,166.174,189.207,208,210.211,
Adopted children 3 212
Affection 47. 99 - Anglo-American 38. 39.41. 42. 43
Affective climate 193 Mexican-American 45
- communication 187. 190 - spanish 39
- relations 37 -. interrater reliability 63
- Style (AS) 52.53.55.57. 189. 190, 191. -. interviewing techniques 98
192.208 -, retest compliance 65
Aftercare X. 4 Catharsis 212
Aggression 102 Chicano 37
Alliance 124 Chronic patients 83
AMDP 82 Chronicity 2
Amotivation 151 Closeness 37
Anger 43.45.47.99.104. 113. 149 Cognitive overload 206
Anhedonia 197 Communication 99, 118, 119. 149. 174, 185.
Antiparkinsonian medication 150 187
Antipathy 43 - deficits 119
Antipsychotic medication 124. 125.210 - Deviance (CD) 104. 214
Anxiety 82. 135. 149 - skills 135
Apathy 105.151 - skills training 119. 125. 175
Approval 56 -. amorphous forms 112
Arousal 29 Community hostel 199
- hypothesis 165 - tenure 192
Assessment 119. 208 Competence 203, 205
Autonomic hyperarousal 206 Compliance 125. 126. 150. 156
- reactivity 203 Conceptual disorganization 210
Autonomy 31, 100 Conflict XI. 1. 118. 147
A voiders 136 Contact time 29
Conversational skills 212
Beck Depression Inventory (BDI) 87, 89 Convulsive treatment 2
Behavioral analysis 119. 174. 175 Coping XL 61. 82, 83,99, 101. 105. 119, 136.
- family therapy 173. 185 147.148.150.152.157.160, 185,187.191.
Belladonna 1 192, 203, 205, 206, 207, 212
Benefits 125 - skills 118
Benign criticism 53, 54 - styles 31. 46. 136. 139
Biobehavioral factors 203 Costs 184
- vulnerabilities 203 Cost-effectiveness 184. 185
Bizarre behavior 210 Crisis 149. 175
Blame 114. 135. 192 - intervention 113
Borderline 4 Critical 56
Brief Psychiatric Rating Scale (BPRS) 57. 179. - comments 39,43.44.45. 88. 90. 98. 161
209, 210 - comments. content analysis 44
Burnt-out 105 - remarks 32. 51. 52. 63
218 Subject Index
Criticism X. 26. 27. 45. 46. 51. 52. 53. 55, 57. - dual high 54
60. 79. 80, 81. 82, 83, 85, 89, 90, 99, 104, 123. - dual low 54
158. 165, 166. 189. 190. 192. 203 - high 27, 28, 29, 30. 31. 32, 33, 36, 41, 43,
- (CRIT) 65 45,46,47, 53, 55, 56, 57,59,60, 61, 63, 64,
65, 66, 67, 73, 74, 77, 85, 86, 88, 89, 90, 93,
94, 98, 99, 101, 102, 103, 104, 105, 113, 118,
Daily management 36
123, 147, 152, 155, 157, 158, 160, 161, 165,
DAS 90,93
188
Decompensation 209
- high, mothers 54
Deficit symptoms 112, 113
- low 27, 28, 29, 30, 31, 32, 33, 41, 43, 44, 45,
Deinstitutionalization 147.215
47, 53, 55, 56, 57, 60, 61. 64, 66, 67. 73. 74.
Delusions 32, 210
77, 85, 86, 88. 90. 93, 94, 98. 99. 100. 101.
Depression X. 32, 87. 89. 100. 208. 210
103, 104. 105. 118. 157, 158, 160
- endogenous 3
- modifications 95
Developing nations 35
- research 97
Diathesis stress model 123, 126, 187
Differential prognosis 35 - criticism 97
Disagreements 90 -. cross-cultural valididty 40. 41, 42
Discharge 14 -. determinants 103
-, development 33
-. psychopathological 16
Disengagement 151 -. ethnicity 42
Distress 43 -. fluctuation over time 103
Divorce 47 -. interactional correlates 51
Dominance 25 -. patient characteristics 42
Double-bind 104 -, psychophysiology 102, 118
-, response styles 31
Drugs antipsychotic 3
-, sociocultural context 47
-, antipsychotic X
- neuroleptic 4 -. socioeconomic status 41,42
DSM-III 109. 110. 111. 112 -. stability of 60
- Emotion, family 36
Dual-parent families 189. 190
- emotion. level of contact 25
Durations of looking 86
Dyadic Adjustment Scale (DAS) 89
Face-to-face contact 28.60. 74. 76. 155. 156.
158. 160. 163. 166
Economic benefits 184 - interaction 85. 86
Education 175 Familial commitment 47
- program 156, 158, 159, 160, 161, 166 - involvement 36
Educational program 131,212 Families mixed EE 54
- programs 109, 110, 112, 113, 114, 120 Familism 37
Electroconvulsive therapy 2 Family assessment 4
Electrodermal activity 29, 30 - assessment task 189
Emotinal overinvolvement 98 - bonds 45,47, 151
Emotional atmosphere 98 - burden 114.182
- Family Atmosphere (EFA) 79,80,81, - communication 119. 173
82.83 - Compliance Index (FCI) 72, 73
- overinvolvement (EOI) X. 25, 26, 27, 39. 53. - conflict 123
54. 55, 56, 57, 60. 63. 65. 68. 81. 83. 86. 98, - education IX, 117, 118, 119, 121, 126, 127,
99, 104, 123, 203 128, 129, 131, 133. 135, 136, 137, 138, 139,
- response 97 185, 206, 212
Empathy 100 - education program 120, 121, 123, 124, 134
Employment status 14 - education, live format 121
Ergotherapy 1 - education, mass media distribution 121
Ethnicity 38 - education, videotape format 121
Events 29 - etiology 123
Expectations 36, 123, 126, 135 - factors 208
Expressed emotion (EE) X, 5, 12,25,26.27, - functioning 30
28, 30, 32, 33, 36, 37, 38, 39,40, 41, 43, 51, - groups 119
52, 53, 57, 59, 61, 63, 65, 67, 73, 76, 77, 79, - interaction XI, 52, 80, 97, 98, 173, 203
85, 86, 89, 94, 97, 98, 102, 104, 105, 118, 119, - interaction, standardized situation 52
130, 147, 148, 149, 152, 155, 158, 159, 163, - intervention programs 113, 117
165, 166, 187, 190, 197, 207, 208, 211 - intervention. acute psychotics 113
Subject Index 219
- involvement 119 Interactions 30, 54, 85, 94
- life XL 97, 98, 104, 147 - direct 53, 98
- management 179, 180, 182, 185, 190 - pattern 90. 93. 94
- ombudsman 134 - style 93
- problem solving 175 - task 53, 57, 189
- programs XI Interactional behavior 52, 55
- stress 123 Intermittent medication, intermittent 193
- support groups 138 Intermorbid adjustment 33
- system 188 International Pilot Study of Schizophrenia
- tension 207 (IPSS) 13. 109
- therapy X, 76, 77, 83,117.119.130.148. Interpersonal boundaries 151
152 - skills 212
- therapy indirect 61 Interrater reliability 63
- therapy psychoeducational X. 60. 61 Intervention research 95
- transactions X Interviewing techniques 98
- treatment. models of X Intolerance 100
Flashbacks 111 Intrusion 189. 190
Flexibility 101. 126. 127 Intrusiveness 31. 46, 53. 55. 56, 57, 98.
Frankfurter Beschwerdebogen (FBF) 82 102. 192
Frustration 43,47.99,100. 102. 113. 133 Irritability 100
Functional analysis 174 Isolation IX. 157