SOP for Sieve Analysis

Standard operating procedure to perform the sieve analysis of various samples.

1.0 OBJECTIVE
To lay down the procedure for sieve analysis.
2.0 SCOPE
This procedure is applicable for sieve analysis of various granules and in-process sample.
3.0 RESPONSIBILITY
3.1 Doing: Technical Assistant
3.2 Checking: Executive /Manager

4.0 ACCOUNTABILITY
Head of the Department
5.0 PROCEDURE
5.1 Use 16, 20, 40 and 60 mesh sieve for sieve analysis.
5.2 Keep in ascending order on each other.
5.3 Weigh 10 to 15 gm of the sample and put it on 16 mesh sieve.
5.4 Stir the granules with stainless steel spatula so that granules above 16 mesh remain on the sieve and finer particles pass through 16 mesh
sieve.
5.5 Note down the weight of finer particles retained above 20 mesh.
5.6 Weigh the granules retained above 40 mesh sieves and stir the granules with a stainless steel spatula.
5.7 Note down the weight of granules collected above 60 mesh sieve and below 60 mesh sieve.
5.8 Calculate the percentage of granules collected below 16 mesh, between 16 to 20 mesh and between 20 to 40 mesh, between 40 to 60 and below
60 mesh sieve. Record the results.
Related: Different Mesh Sizes Used in Pharmaceuticals and Their Conversion
6.0 ABBREVIATIONS
6.1 SOP - Standard Operating Procedure

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