Mannitol

Drugs
Urea
Chlorothiazide
treat increased intracranial thiazide
Osmitics agents
pressure
Hydrochlorothiazide

clinical uses Drugs

Acute renal failure
Indapamide
thiazide like
acute angle-closure Glaucoma
Metolazone

Mountain sickness Acetazolamide

Increase sodium excretion

Carbonic anhydrase
Open-angle glaucoma Dorzolamide Drugs
Inhibitors Increase potassium loss

Open-angle glaucoma Brinzolamide

Increase magnesium loss

They act promptly even in poor Actions Decrease calcium excretion

renal function

Reduce peripheral vascular

Increase Na+, K+, Ca+2 renal
resistance
excretion

Actions
NSAID’s can reduce the diuretics
Hypocalcemia doesn’t occur Thiazides (Low ceiling action
Diuretics)
Enhance renal blood perfusion
mild to moderate hypertension

NSAIDs reduce there action

heart failure
Diuretics
Therapeutic uses
For pulmonary edema
idiopathic hypercalciuria
Acute/chronic peripheral edema

nephrogenic diabetes insipidus

Emergency pulmonary edema
Therapeutic uses
hypokalemia
With hydration to treat
hypercalcemia
Loop diuretics Hypernatremia
(High ceiling
Treat hyperkalemia Diuretics)
Hyperurecemia
Ototoxicity Adverse effects
Volume depletion
Hyperuricemia
Hypercalcemia
Acute hypovolemia Adverse effects
hyperglycemia
Hypoklalemic alkalosis
Spironolactone
Hypomagnesemia Aldosterone antagonists
Eplerenone
Potassium sparing Diuretics
Furosemide (Decrease potassium Elimination)
Amiloride
Bumetanide Sodium channels blockers
Drugs Triametrene
Torsemide

Ethacrinic acid