Pre-conception Antenatal Newborn

Blood for haemoglobin, group, rhesus and Blood for syphilis, hepatitis B and HIV For babies of hepatitis B positive
antibodies as early as possible, or as soon as a as early as possible, or at any stage of mothers, give hepatitis B vaccination
woman arrives for care, including labour the pregnancy, including labour +/- immunoglobulin within 24 hours

Commence Blood for sickle Blood for T21, Blood for T21 Reoffer screening for Repeat Newborn physical Newborn Infant physical
folic acid cell and T18 and T13 (quadruple infectious diseases if haemoglobin examination hearing examination
thalassaemia (combined test) test) initially declined and antibodies by 72 hours screen at 6 to 8 weeks

Week 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 +1 +2 +3 +4 +5 +6

BIRTH
Early pregnancy Detailed ultrasound scan for Give and discuss newborn Newborn blood spot screens
Women with type 1 or
scan to support structural abnormalities, screening information (ideally on day 5) for:
type 2 diabetes are
T21, T18 and T13 including T18 and T13 sickle cell disease (SCD),
offered diabetic eye (DE)
screening cystic fibrosis (CF), congenital
screening annually. In
pregnancy women with hypothyroidism (CHT) and inherited
type 1 or type 2 Further DE metabolic diseases (PKU, MCADD,
diabetes are offered a Follow-up DE screen for screen for MSUD, IVA, GA1 and HCU)
DE screen when they women with type 1 or 2 women with Note that babies who missed the
first present for care diabetes found to have type 1 or 2 screen can be tested up to one year
diabetic retinopathy diabetes (except CF offered up to 8 weeks)

Give
screening
information
as soon as
possible
Key to screening programmes
• Fetal anomaly (Down’s syndrome/T21, Edwards’ • Newborn and infant
syndrome/T18, Patau’s syndrome/T13, and fetal physical examination
anomaly ultrasound) • Newborn blood spot
• Infectious diseases in pregnancy • Newborn hearing
• Sickle cell and thalassaemia • Diabetic eye

Antenatal and newborn screening timeline – optimum times for testing

Screening should be a personal informed choice. Women and their families should be supported to understand the tests and choose what’s right for them.
Version 8.4, January 2019, Gateway ref: 2014696, www.gov.uk/phe/screening