Download as pdf or txt
Download as pdf or txt
You are on page 1of 48

Biology 12th Edition Mader Test Bank

Go to download the full and correct content document:


https://testbankdeal.com/product/biology-12th-edition-mader-test-bank/
More products digital (pdf, epub, mobi) instant
download maybe you interests ...

Human Biology 12th Edition Mader Test Bank

https://testbankdeal.com/product/human-biology-12th-edition-
mader-test-bank/

Biology 12th Edition Mader Solutions Manual

https://testbankdeal.com/product/biology-12th-edition-mader-
solutions-manual/

Biology 10th Edition Mader Test Bank

https://testbankdeal.com/product/biology-10th-edition-mader-test-
bank/

Biology 11th Edition Mader Test Bank

https://testbankdeal.com/product/biology-11th-edition-mader-test-
bank/
Human Biology 13th Edition Mader Test Bank

https://testbankdeal.com/product/human-biology-13th-edition-
mader-test-bank/

Human Biology 14th Edition Mader Test Bank

https://testbankdeal.com/product/human-biology-14th-edition-
mader-test-bank/

Human Biology 15th Edition Mader Test Bank

https://testbankdeal.com/product/human-biology-15th-edition-
mader-test-bank/

Essentials of Biology 4th Edition Mader Test Bank

https://testbankdeal.com/product/essentials-of-biology-4th-
edition-mader-test-bank/

Essentials of Biology 5th Edition Mader Test Bank

https://testbankdeal.com/product/essentials-of-biology-5th-
edition-mader-test-bank/
Chapter 09 - The Cell Cycle and Cellular Reproduction

Chapter 09
The Cell Cycle and Cellular Reproduction

Multiple Choice Questions

1. What structure will code for the proteins that will promote the normal cell cycle and
prevent apoptosis?
A. tumor suppressor genes
B. oncogenes
C. caspases
D. proto-oncogenes

Proto-oncogenes code for proteins that promote the normal cell cycle and prevent apoptosis.

Bloom's Level: 1. Remember


Learning Outcome: 09.04.03 Distinguish between the roles of the tumor suppressor genes and proto-oncogenes in the regulation of the cell
cycle.
Section: 09.04
Topic: Cancer

True / False Questions

2. Viruses and chemical exposure can cause mutations in proto-oncogenes which can lead to
cancer.
TRUE

Bloom's Level: 3. Apply


Learning Outcome: 09.04.03 Distinguish between the roles of the tumor suppressor genes and proto-oncogenes in the regulation of the cell
cycle.
Section: 09.04
Topic: Cancer

9-1
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Essay Questions

3. Write an essay that explains how a geneticist could attempt to prevent cancer by
manipulating a persons proto-oncogenes.

Answers may vary but the essay should discuss that when mutations occur in proto-
oncogenes they can become oncogenes. It is the oncogene that is the cancer causing gene. So
if a geneticist was wishing to prevent cancer they could find a way to genetically manipulate
the proto-oncogenes to prevent them from mutating into oncogenes.

Bloom's Level: 6. Create


Learning Outcome: 09.04.03 Distinguish between the roles of the tumor suppressor genes and proto-oncogenes in the regulation of the cell
cycle.
Section: 09.04
Topic: Cancer

Multiple Choice Questions

4. Which of the following is NOT true concerning mitosis?


A. Plant cells lack centrioles while animal cells do not.
B. Both plant and animal cells undergo cytokinesis.
C. Mitosis allows growth and increase in size in both plants and animals.
D. Animal cells form a cell plate during cytokinesis while plant cells do not.

Bloom's Level: 2. Understand


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-2
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

5. Cancer cells require many nutrients, which are supplied by blood vessels. The growth of
new blood vessels to cancerous tissue is called
A. angiogenesis.
B. metastasis.
C. carcinogenesis.
D. apotosis.

The growth of new blood vessels to cancerous tissue is called angiogenesis.

Bloom's Level: 1. Remember


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

6. Apoptosis
A. is programmed cell death.
B. is a process that acts to decrease the number of somatic cells.
C. frees the fingers and toes of the human embryo from their ‘webbed' structure to
independent structures.
D. All of the choices are correct.

All of the choices are correct about apoptosis.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.02 List the checkpoints that regulate the progression of cells through the cell cycle.
Section: 09.01
Topic: Apoptosis

9-3
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

7. The region that contains the genetic information in a bacterial cell is called the
A. nucleus.
B. nucleoid.
C. nucleolus.
D. nucleosome.
E. nucleoprotein.

The region that contains the genetic information in a bacterial cell is called the nucleoid.

Bloom's Level: 1. Remember


Learning Outcome: 09.05.01 Distinguish between the structures of a prokaryotic and eukaryotic chromosome.
Section: 09.05
Topic: Prokaryote Reproduction

8. Virtually all specialized cells of multicellular organisms


A. develop through mutation from less specialized cells of the organism.
B. contain more genetic material than less specialized cells of the same organism.
C. contain less genetic material than less specialized cells of the same organism.
D. have the same amount of DNA and the same number of chromosomes as all other cells of
the organism and develop from the same basic stem cells.

Virtually all specialized cells of multicellular organisms have the same amount of DNA and
the same number of chromosomes as all other cells of the organism and develop from the
same basic stem cells.

Bloom's Level: 2. Understand


Learning Outcome: 09.03.03 Discuss why human stem cells continuously conduct mitosis.
Section: 09.03
Topic: Mitosis

9-4
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

9. If a parent cell has 48 chromosomes, how many chromosomes will each daughter cell have
after mitosis and cytokinesis occurs?
A. 24 chromosomes
B. 48 chromosomes
C. 12 chromosomes
D. 96 chromosomes

If a parent cell has 48 chromosomes, each daughter cell have 48 chromosomes after mitosis
and cytokinesis.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

10. Interphase:
A. occupies the majority of the cell cycle
B. includes G1, S and G2 stages
C. results in an increase in cell size
D. All of the answer choices are correct.
E. None of the answer choices are correct.

All of the choices are true. Interphase occupies the majority of the cell cycle, includes G1, S
and G2 stages and results in an increase in cell size.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.01 List the stages of interphase, and describe the major events that occur during each stage in preparation for cell
division.
Section: 09.01
Topic: Cell Cycle

9-5
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

11. Eukaryotic chromosomes


A. consist of both DNA and protein.
B. may occur as chromatin.
C. contain histones responsible for packaging DNA to fit into a small space.
D. All of the choices are correct.

Eukaryotic chromosomes consist of both DNA and protein, may occur as chromatin and
contain histones responsible for packaging DNA to fit into a small space. All choices are
correct.

Bloom's Level: 2. Understand


Learning Outcome: 09.05.01 Distinguish between the structures of a prokaryotic and eukaryotic chromosome.
Section: 09.05
Topic: Chromosome Structure

True / False Questions

The enzymes that bring about apoptosis are:

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Apoptosis

12. called caspases.


TRUE

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Apoptosis

9-6
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

13. are ordinarily held in check by inhibitors.


TRUE

It is true that the enzymes that bring about apoptosis are ordinarily held in check by inhibitors.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Apoptosis

14. can be unleashed by internal or external signals.


TRUE

It is true that the enzymes that bring about apoptosis can be unleashed by internal or external
signals.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Apoptosis

15. are only present in the cell immediately before apoptosis begins.
FALSE

The enzymes that bring about apoptosis are always present in the cell, but are controlled by
internal and external signals.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Apoptosis

9-7
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Multiple Choice Questions

16. Generally, animals build an organism using the diploid number of chromosomes.
However, insects in the order of ants, wasps and bees can use a haploid-diploid system where
adults of one sex are formed with a haploid number of chromosomes. This would mean that
A. a single set of chromosomes is sufficient to code for a functional individual.
B. a female could determine the sex of the offspring by fertilizing or not fertilizing an egg.
C. the males and females are not equally "related" to their mothers considering the proportion
of genes held in common.
D. All of the choices are true.
E. this system in no way differs from regular diploid organisms.

All of the choices are true.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

17. What is the result of a cell not meeting the criteria to pass the G1 checkpoint?
A. The cell cycle halts.
B. The cell may enter the G0 stage.
C. The cell may undergo apoptosis.
D. All of these.
E. None of these.

The result of a cell not meeting the criteria to pass the G1 checkpoint is the cell cycle halting,
and the cell may enter the G0 stage or undergo apoptosis.

Bloom's Level: 2. Understand


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Cell Cycle

9-8
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

18. Which is NOT true about the chromosomes of a multicellular organism?


A. They are made up of DNA and protein.
B. Each chromosome is replicated into two chromatids during the S phase of interphase.
C. Each chromosome separates into two daughter chromosomes by binary fission.
D. All cells contain chromosomes that carry the same genetic information.

Bloom's Level: 2. Understand


Learning Outcome: 09.03.01 Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Section: 09.03
Topic: Chromosome Structure

19. The function of mitosis is:


A. growth of the organism and tissue repair.
B. to ensure that each new cell receives a complete set of genetic information.
C. asexual reproduction in some species.
D. All of the choices are correct.

The function of mitosis includes all of the choices: growth and repair, to ensure that each new
cell receives a complete set of genetic material and asexual reproduction in some species.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

20. Which statement is NOT true about eukaryotic chromosomes?


A. There is only one chromosome of each type in each body cell.
B. Chromosomes contain both DNA and associated histones.
C. Chromosomes condense from chromatin at the start of mitosis.
D. Chromosomes disperse back into chromatin at the end of mitosis.
E. Chromosomes are not located within the nuclear envelope during mitosis.

It is not true that there is only one chromosome of each type in each body cell. There are two
chromosomes of each kind, one maternal and one paternal chromosome.

Bloom's Level: 2. Understand


Learning Outcome: 09.05.01 Distinguish between the structures of a prokaryotic and eukaryotic chromosome.
Section: 09.05
Topic: Chromosome Structure

9-9
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

21. The diploid (2n) number of chromosomes for a human being is


A. 23.
B. 24.
C. 44.
D. 46.
E. 48.

The diploid (2n) number of chromosomes for humans is 46.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.01 Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Section: 09.03
Topic: Chromosome Structure

22. The haploid (n) number of chromosomes for a human being is


A. 23.
B. 24.
C. 44.
D. 46.
E. 48.

The haploid (n) number of chromosomes for humans is 23.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.01 Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Section: 09.03
Topic: Chromosome Structure

9-10
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

23. Which statement is NOT true about mitosis?


A. Mitosis is a process that duplicates and divides the nuclear contents only.
B. Mitosis produces two daughter cells that contain the same number of chromosomes as the
parent cell.
C. Mitosis produces two daughter cells that contain the same kinds of chromosomes as the
parent cell.
D. Mitosis uses a diploid (2n) parent cell to form daughter cells containing a haploid
number(n) of chromosomes.
E. Mitosis is involved in development of a fertilized egg into a multicellular organism.

It is not true that mitosis uses a 2n parent cell to form daughter cells containing n
chromosomes. Mitosis produces two daughter cells that contain the same number of
chromosomes as the parent cell.

Bloom's Level: 2. Understand


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

24. Which represents the correct sequence of stages in the cell cycle?
A. G1, G2, S, M
B. G1, G2, M, S
C. G1, M, G2, S
D. G1, S, G2, M

The correct sequences of stages in the cell cycle is: G1, S, G2, M.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.01 List the stages of interphase, and describe the major events that occur during each stage in preparation for cell
division.
Section: 09.01
Topic: Cell Cycle

9-11
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

25. Below the skin are "stem cells" that divide, with some cells continuing the stem cell line
and others being pushed toward the surface to flatten and die and be sloughed off. In the bone
marrow other stem cells produce erythrocytes that lose their nucleus and function for a few
months in the bloodstream before they too die. Such "dead end" cells that reproduce no
further
A. leave the cell cycle in a G0 phase, which immediately follows telophase.
B. leave the cell cycle in a G3 phase, which immediately follows G2.
C. halt in the midst of the S phase.
D. continually cycle but simply fail to go through cytokinesis.
E. reverse from G2 to G1.

Such "dead end" cells that reproduce no further leave the cell cycle in a G0 phase, which
immediately follows telophase.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.03 Discuss why human stem cells continuously conduct mitosis.
Section: 09.03
Topic: Mitosis

26. What factors are evaluated before a cell is allowed to proceed through the G1 checkpoint?

A. growth signals
B. availability of nutrients
C. the integrity of cellular DNA
D. all of these
E. none of these

Growth signals, availability of nutrients and the integrity of DNA are evaluated before a cell
is allowed to proceed through the G1 checkpoint.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Cell Cycle

9-12
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

27. The critical checkpoints that control the cell cycle are the
A. M to G1 stage and G2 to M stage.
B. S to G2 stage and G2 to M stage.
C. G1 to S stage and G2 to M stage.
D. M to G1 stage and S to G2 stage.

The critical checkpoints that control the cell cycle are at the G1 to S stage and G2 to M stage.

Bloom's Level: 2. Understand


Learning Outcome: 09.01.02 List the checkpoints that regulate the progression of cells through the cell cycle.
Section: 09.01
Topic: Cell Cycle

28. During which stage of the cell cycle is cell growth and replication of organelles most
significant?
A. M phase
B. G1 phase
C. G2 phase
D. S phase
E. G0 phase

During the G1 stage of the cell cycle, cell growth and replication of organelles is significant.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.01 List the stages of interphase, and describe the major events that occur during each stage in preparation for cell
division.
Section: 09.01
Topic: Cell Cycle

9-13
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

29. Which stage is most associated with a cell that is unable to divide again, such as a muscle
or nerve cell?
A. M phase
B. G1 phase
C. G2 phase
D. S phase
E. G0 phase

Nerve and muscle cells typically do not complete the cell cycle, have entered the G0 stage
and are permanently arrested.

Bloom's Level: 2. Understand


Learning Outcome: 09.01.01 List the stages of interphase, and describe the major events that occur during each stage in preparation for cell
division.
Section: 09.01
Topic: Cell Cycle

30. Which sequence of stages in mitosis is correct?


A. prophase, anaphase, prometaphase, metaphase, telophase
B. prophase, telophase, anaphase, prometaphase, metaphase
C. prophase, prometaphase, metaphase, anaphase, telophase
D. telophase, anaphase, prophase, prometaphase, metaphase
E. anaphase, prometaphase, metaphase, prophase, telophase

The sequence of stages in mitosis is: prophase, prometaphase, metaphase, anaphase,


telophase.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-14
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

31. In some organisms, mitosis occurs without cytokinesis. This results in


A. cell death.
B. a multinucleated cell.
C. cells arrested in the G0 phase.
D. cells with no nucleus.
E. uncontrolled cell division.

If mitosis occurs without cytokinesis, then the cell will be multinucleated.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

32. What occurs in anaphase?


A. Centrioles move to opposite poles.
B. Chromosomes move to opposite poles.
C. Chromosomes line up along the equator of the dividing cell.
D. The nuclear envelope disappears.
E. The nuclear envelope is constructed.

In anaphase, chromosomes move to opposite poles.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

33. Which does NOT occur in telophase?


A. Cytokinesis is under way.
B. The nuclear envelope is being reconstructed.
C. The centromeres split apart.
D. Chromosomes de-condense into chromatin.
E. The nucleolus reforms.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-15
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

34. Cytokinesis in plant cells differs from this process in animal cells because
A. the plant endoplasmic reticulum forms a cell plate.
B. microtubules are laid down in a plywood-like cell plate pattern.
C. the Golgi apparatus produces vesicles that migrate along microtubules and fuse to become
a cell plate.
D. the inner plasma membrane divides by cytokinesis as in animal cells and then secretes a
cellulose cell wall.
E. asters coalesce to form a fibrous plate that reinforces with cellulose.

Cytokinesis in plant cells differs from this process in animal cells because the Golgi
apparatus produces vesicles that migrate along microtubules and fuse to become a cell plate.

Bloom's Level: 2. Understand


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

35. Binary fission in bacteria differs from mitosis because


A. the chromosome copies attach to the plasma membrane and are pulled apart by cell growth.
B. the chromosome is a simple DNA strand without complex proteins and no spindle forms.
C. there is no nuclear membrane to break down and rebuild.
D. All of the choices are correct.
E. None of the choices are correct.

Bloom's Level: 2. Understand


Learning Outcome: 09.05.02 Describe the events that occur during binary fission.
Section: 09.05
Topic: Prokaryote Reproduction

9-16
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

36. Oncogenes are all of the following EXCEPT


A. mutated proto-oncogenes.
B. cancer causing genes.
C. genes that stimulate uncontrolled cell divisions.
D. tumor suppressor genes.

Oncogenes are mutated proto-oncogenes, cause cancer and stimulate uncontrolled cell
divisions. They are not tumor suppressor genes.

Bloom's Level: 2. Understand


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

37. Which of the following is NOT true about cancer cells?


A. They never fully differentiate.
B. They exhibit contact inhibition.
C. They exhibit uncontrolled growth.
D. They exhibit disorganized growth.
E. They may undergo metastasis.

Bloom's Level: 2. Understand


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

38. Which is NOT correctly associated with cancer?


A. Angiogenesis forms new blood vessels and brings nutrients and oxygen to the tumor.
B. The disorganized mass of cells is encapsulated and does not invade adjacent tissue.
C. Metastasis establishes new tumors distant from the site of the primary tumor.
D. Cells have receptors to adhere to basement membranes, then secrete proteinase enzymes
to invade underlying tissues.

Bloom's Level: 2. Understand


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

9-17
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

39. Angiogenesis
A. is the growth of blood vessels into the tumor.
B. is directed by additional mutations in tumor cells.
C. brings nutrients and oxygen to a tumor.
D. all of these.
E. none of these.

All of the choices are correct. Angiogenesis, which is directed by additional mutations, is the
growth of blood vessels into the tumor. It brings nutrients and oxygen to a tumor.

Bloom's Level: 1. Remember


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

40. Although cancer may originate in many regions of the body, many patients die from
cancerous growth in the lungs, lymph glands, or liver. This is most readily explained as
A. spreading of cancer by angiogenesis.
B. metastasis occurring more commonly in organs that have a filter effect.
C. proteinase enzymes making cancer particularly damaging to these tissues.
D. growth anywhere but in these organs is called benign.
E. due to these organs simply being more susceptible to cancer.

This is most readily explained as metastasis occurring more commonly in organs that have a
filter effect.

Bloom's Level: 3. Apply


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

9-18
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

41. Apoptosis refers to cell death and


A. is always biologically detrimental to an organism.
B. is merely the accumulation of genetic errors.
C. is any failure of the genetic machinery to work properly.
D. is a failure in the translation or transcription mechanism.
E. can be programmed and is essential to normal development.

Apoptosis refers to cell death, can be programmed and is essential to normal development.

Bloom's Level: 1. Remember


Learning Outcome: 09.01.03 Explain the mechanisms within the G1 cell cycle checkpoint that evaluate growth signals, determine nutrient
availability, and assess DNA integrity.
Section: 09.01
Topic: Cell Cycle

42. The purpose of therapeutic cloning is


A. to produce an individual to the donor of the nucleus.
B. to produce specialized tissue cells.
C. to stimulate cells that have been arrested in the S phase.
D. None of the answer choices are correct.

The purpose of therapeutic cloning is to produce specialized tissue cells.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.03 Discuss why human stem cells continuously conduct mitosis.
Section: 09.03
Topic: Mitosis

9-19
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

43. What phase of mitosis is pictured?

A. prophase
B. prometaphase
C. metaphase
D. anaphase
E. telophase

Bloom's Level: 4. Analyze


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-20
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

44. What is (are) the structures designated by the letter ‘A'?

A. spindle fibers
B. centrioles
C. chromosomes
D. kinetochore microtubules

These are chromosomes aligned along the metaphase plate.

Bloom's Level: 4. Analyze


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-21
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

45. What phase of mitosis is pictured?

A. prophase
B. prometaphase
C. metaphase
D. anaphase
E. telophase

This is metaphase. The chromosomes are all at the metaphase plate.

Bloom's Level: 4. Analyze


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

Short Answer Questions

9-22
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

46. Name the labeled structures in the figure and answer the following questions.

A. _______________
B. _______________
C. _______________
D. When the structures labeled A separate, what are they called?
E. What is the function of the structure labeled C?

A. Sister chromatids
B. Centromeres
C. Kinetochore
D. As the sister chromatids separate, they are called daughter chromosomes.
E. The kinetochores link each sister chromatid to the mitotic spindle.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.01 Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Section: 09.03
Topic: Chromosome Structure

9-23
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Multiple Choice Questions

47. Generally, complex organisms do require more genes to control their synthesis and
organization than do primitive organisms. However, the numbers of chromosomes vary from
ants with 2, molds with 8-14, humans with 46, potatoes with 100 and the crayfish with 200!
Some birds and insects have chromosomes that dwindle in size into obscurity, so it is not
possible to establish a diploid number. How do you explain this situation?
A. There must be no relationship between amount of genetic information and complexity of
the organism.
B. The number of genes per chromosome may vary among organisms, preventing a simple
relationship between chromosome number and complexity.
C. Birds and insects probably cannot follow the same mitotic laws as other organisms.
D. All of the choices are correct.

Given this information, then the number of genes per chromosome may vary among
organisms, preventing a simple relationship between chromosome number and complexity.

Bloom's Level: 3. Apply


Learning Outcome: 09.03.01 Explain how the cell prepares the chromosomes and centrosomes prior to nuclear division.
Section: 09.03
Topic: Chromosome Structure

9-24
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Short Answer Questions

48. Answer the following questions concerning the following figure.

A. Name the structure labeled A.


B. What process is occurring in the figure?
C. Is this an animal or plant cell? Explain

A. ‘A' is the cleavage furrow.


B. Cytokinesis is occurring.
C. This is an animal cell, which is forming a contractile ring in the process of cytokinesis.
Plant cells have a rigid cell wall, are not as flexible as animal cells and do not form cleavage
furrows. Plant cells form cell plates and lay down new cell walls between the daughter cells
during cytokinesis.

Bloom's Level: 4. Analyze


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-25
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Multiple Choice Questions

49. The event that signals the start of anaphase is


A. division of the centromeres to separate sister chromatids.
B. migration of the centrioles to opposite poles of the nuclear space.
C. a cleavage furrow starts to form.
D. asters disappear.

The event that signals the start of anaphase is division of the centromeres to separate sister
chromatids, giving rise to two daughter chromosomes.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

True / False Questions

50. Cloning can only be carried out using adult stem cells.
FALSE

It is not true that cloning can only be carried out using adult stem cells. Embryonic stem cells
can be used as well.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.03 Discuss why human stem cells continuously conduct mitosis.
Section: 09.03
Topic: Mitosis

9-26
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

51. Contact inhibition stops normal cells from dividing when they come in contact with
neighboring cells, but this is not functional in cancer cells.
TRUE

It is true that normal cells exhibit contact inhibition, but cancer cells do not.

Bloom's Level: 2. Understand


Learning Outcome: 09.04.01 Describe the basic characteristics of cancer cells.
Section: 09.04
Topic: Cancer

52. Generally, brain and nerve cells are not able to regenerate after injury because they have
left the cell cycle and are unable to return.
TRUE

It is true that, generally, brain and nerve cells are not able to regenerate after injury because
they have left the cell cycle and are unable to return.

Bloom's Level: 2. Understand


Learning Outcome: 09.01.01 List the stages of interphase, and describe the major events that occur during each stage in preparation for cell
division.
Section: 09.01
Topic: Cell Cycle

53. Organisms produced as a result of mitosis exhibit a great deal of genetic variation.
FALSE

It is not true that organisms produced as a result of mitosis exhibit a great deal of genetic
variation.

Bloom's Level: 1. Remember


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-27
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

Multiple Choice Questions

54. Which statement below best describes the difference between mitosis and cytokinesis?
A. Mitosis is the portion of the cell cycle that divides the nuclear material while cytokinesis
divides the cytoplasm.
B. Mitosis is the portion of the cell cycle that divides the cytoplasm while cytokinesis divides
the nuclear material.
C. Mitosis is the portion of the cell cycle that uses a contractile ring to divide the nuclear
material while cytokinesis uses the contractile ring to divide the cell membrane.
D. Mitosis is the portion of the cell cycle that uses a cell plate to divide the cell membrane in
plant cells while cytokinesis uses a contractile ring to divide the cell membrane in animal
cells.

Bloom's Level: 5. Evaluate


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

55. Which statement below lists the correct steps for binary fission?
A. 1. attachment of chromosome to the plasma membrane, 2. enlargement of cell volume, 3.
DNA replication occurs, 4. cell elongates and chromosomes are pulled apart, 5. a new cell
wall and plasma membrane divide the cell in half
B. 1. attachment of chromosome to the plasma membrane, 2. enlargement of cell volume, 3.
DNA replication occurs, 4. a new cell wall and plasma membrane divide the cell in half, 5.
cell elongates and chromosomes are pulled apart
C. 1. a new cell wall and plasma membrane divide the cell in half, 2. attachment of
chromosome to the plasma membrane, 3. enlargement of cell volume, 4. DNA replication
occurs, 5. cell elongates and chromosomes are pulled apart
D. 1. enlargement of cell volume, 2. attachment of chromosome to the plasma membrane, 3.
DNA replication occurs, 4. cell elongates and chromosomes are pulled apart, 5. a new cell
wall and plasma membrane divide the cell in half

The correct steps are: 1. attachment of chromosome to the plasma membrane, 2. enlargement
of cell volume, 3. DNA replication occurs, 4. cell elongates and chromosomes are pulled
apart, 5. a new cell wall and plasma membrane divide the cell in half.

Bloom's Level: 5. Evaluate


Learning Outcome: 09.05.02 Describe the events that occur during binary fission.
Section: 09.05
Topic: Prokaryote Reproduction

9-28
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Chapter 09 - The Cell Cycle and Cellular Reproduction

56. Which of the following statements applies to mitosis but not to cytokinesis?
A. it contains a checkpoint that will evaluate the quality of the cell
B. requires a large amount of ATP in order for the cellular mechanisms to function
C. if it is disrupted it can lead to an abnormal cell
D. it results in two daughter cells that are half the size of the original cell

Bloom's Level: 5. Evaluate


Learning Outcome: 09.03.02 Summarize the major events that occur during mitosis and cytokinesis.
Section: 09.03
Topic: Mitosis

9-29
Copyright © 2016 McGraw-Hill Education. All rights reserved. No reproduction or distribution without the prior written consent of
McGraw-Hill Education.
Another random document with
no related content on Scribd:
Ristiriitaiset tunteet, toivo ja epätoivo repivät häntä, Mistä saada
varmuus? — Mitä oli vartija sanonut. Tiesikö hän ihmisuhreista?

Irja joutui jälleen epätoivoon. Hän ei nähnyt mitään pelastumisen


mahdollisuutta.

Silloin puhkesivat kyynelten lähteet…

Yön tunnit kuluivat. Hänellä oli vain tuska, itsesyytös, epätoivo,


kärsimys… Näinä hetkinä oli hän elämänsä elänyt, taistelunsa
taistellut. Poissa oli hän, joka siihen sisällön olisi antanut.

Viettäessään näitä raskaita hetkiä oli hän kuullut, kuinka


ratapihalla oli ollut liikettä. Veturi oli liikkunut toisessa päässä ja
kadonnut. Mitkä viestit sillä oli mukanansa palatessaan? Hän oli ollut
jo monta kertaa aivan pukeutumaisillaan lähteäkseen asemalle,
mutta häntä oli peloittanut kuulla pahinta. Hän ei olisi voinut kestää
sitä. Epätoivoisena virui hän vuoteellaan.

Taivaan rantaan kohosi päivän kajastus…

Hän katsoi sitä rukoillen ja sielussaan toivoi sen tuovan mukanaan


toivon säteen…

Ja niinkuin sen elähdyttämänä alkoi hän pukeutua, itsekään


tietämättä, miksi. Konttoriin ei hän voisi mennä nyt, hän oli liiaksi
järkytetyllä mielellä kohdataksensa ketään. Ehkä yövartijoilta voisi
jotakin kuulla. Hän läksi ulos ja etsi katseellaan yövartijan lyhtyä,
löytämättä sitä.

Tuuli vihelsi puiden paljaissa oksissa. Yhtäkkiä hän pysähtyi:


loihtiko hermostunut mielikuvitus harhailevia ääniä esiin vai yhtyikö
todellakin myrskyn pauhuun junan vihellys? Irja pysähtyi. Ilma puhui
pitkään, yhtämittaa, kunnes eräässä virtansa käänteessä lennätti
tutun kolinan… Miltä suunnalta? Sieltä, sieltä… Seurasi uusi toivon
ja epätoivon kamppailu. Vapisten seisoi Irja koettaen katsoa, peljäten
näkevänsä. Tulomerkistä junan saapumiseen tuntui olevan
kokonainen iankaikkisuus, jonka kestäessä mitä synkimmät ja
ihanimmat kuvat vaihtelivat hänen mielessään…

Vihdoin ilmestyi veturi tenderi edellä, häämöittivät


matkustajavaunut. Irja kerkesi parahiksi sille paikalle, jonne veturi
pysähtyi. Hän ei tahtonut nähdä kyyneliensä läpi, ja kun Erkki hänet
huomattuaan tuli alas, täytyi Irjan tarttua häneen pysyäkseen
pystyssä.

Nähdessään Irjan äkkiä koneensa vieressä, välähti Erkin


mielessä: mistä tämä huomaavaisuus? Samalla hän myöskin vilkaisi
konttorin akkunoihin. Mutta silloin hän tunsi Irjan kosketuksen ja
hänen sielunsa täytti valtavan voimakas tunne.

"Erkki", sanoi Irja, koettaen itseään hillitä, "olen kärsinyt tänä


aamuyönä niin etten voi sitä sanoa; tiedot tulivat niin epämääräisinä,
enkä ole voinut tietää, oletko sinä kuollut vai oletko elossa vielä…"

Erkki kuunteli Irjan sanoja ihmeissään. Sitten hänestä tuntui kuin


olisi hän herännyt pitkästä unesta.

"Oletko sinä ollut minusta huolissasi?" kysyi hän miltei katkerasti.

Mutta kuvaamaton, kyyneleinen katse vastasi hänelle enemmän


kuin sanat. Lämmin aalto tulvahti hänen sydämeensä. Hän puristi
hentoa, vavahtelevaa kättä ja hänen äänensä soi kuin riemukas
laulu, kun hän hiljaa sanoi:
"Odota, Irja, odota hetkinen!"

Hän nousi veturiinsa, katsoakseen, että kaikki oli kunnossa. Mutta


sydän jyskytti ja suonet tykkivät kuumeessa.

"Hän rakastaa minua, hän rakastaa minua", soi riemuunsa


pakahtuva sävel hänen rinnassaan.
*** END OF THE PROJECT GUTENBERG EBOOK VAIHTEISSA ***

Updated editions will replace the previous one—the old editions will
be renamed.

Creating the works from print editions not protected by U.S.


copyright law means that no one owns a United States copyright in
these works, so the Foundation (and you!) can copy and distribute it
in the United States without permission and without paying copyright
royalties. Special rules, set forth in the General Terms of Use part of
this license, apply to copying and distributing Project Gutenberg™
electronic works to protect the PROJECT GUTENBERG™ concept
and trademark. Project Gutenberg is a registered trademark, and
may not be used if you charge for an eBook, except by following the
terms of the trademark license, including paying royalties for use of
the Project Gutenberg trademark. If you do not charge anything for
copies of this eBook, complying with the trademark license is very
easy. You may use this eBook for nearly any purpose such as
creation of derivative works, reports, performances and research.
Project Gutenberg eBooks may be modified and printed and given
away—you may do practically ANYTHING in the United States with
eBooks not protected by U.S. copyright law. Redistribution is subject
to the trademark license, especially commercial redistribution.

START: FULL LICENSE


THE FULL PROJECT GUTENBERG LICENSE
PLEASE READ THIS BEFORE YOU DISTRIBUTE OR USE THIS WORK

To protect the Project Gutenberg™ mission of promoting the free


distribution of electronic works, by using or distributing this work (or
any other work associated in any way with the phrase “Project
Gutenberg”), you agree to comply with all the terms of the Full
Project Gutenberg™ License available with this file or online at
www.gutenberg.org/license.

Section 1. General Terms of Use and


Redistributing Project Gutenberg™
electronic works
1.A. By reading or using any part of this Project Gutenberg™
electronic work, you indicate that you have read, understand, agree
to and accept all the terms of this license and intellectual property
(trademark/copyright) agreement. If you do not agree to abide by all
the terms of this agreement, you must cease using and return or
destroy all copies of Project Gutenberg™ electronic works in your
possession. If you paid a fee for obtaining a copy of or access to a
Project Gutenberg™ electronic work and you do not agree to be
bound by the terms of this agreement, you may obtain a refund from
the person or entity to whom you paid the fee as set forth in
paragraph 1.E.8.

1.B. “Project Gutenberg” is a registered trademark. It may only be


used on or associated in any way with an electronic work by people
who agree to be bound by the terms of this agreement. There are a
few things that you can do with most Project Gutenberg™ electronic
works even without complying with the full terms of this agreement.
See paragraph 1.C below. There are a lot of things you can do with
Project Gutenberg™ electronic works if you follow the terms of this
agreement and help preserve free future access to Project
Gutenberg™ electronic works. See paragraph 1.E below.
1.C. The Project Gutenberg Literary Archive Foundation (“the
Foundation” or PGLAF), owns a compilation copyright in the
collection of Project Gutenberg™ electronic works. Nearly all the
individual works in the collection are in the public domain in the
United States. If an individual work is unprotected by copyright law in
the United States and you are located in the United States, we do
not claim a right to prevent you from copying, distributing,
performing, displaying or creating derivative works based on the
work as long as all references to Project Gutenberg are removed. Of
course, we hope that you will support the Project Gutenberg™
mission of promoting free access to electronic works by freely
sharing Project Gutenberg™ works in compliance with the terms of
this agreement for keeping the Project Gutenberg™ name
associated with the work. You can easily comply with the terms of
this agreement by keeping this work in the same format with its
attached full Project Gutenberg™ License when you share it without
charge with others.

1.D. The copyright laws of the place where you are located also
govern what you can do with this work. Copyright laws in most
countries are in a constant state of change. If you are outside the
United States, check the laws of your country in addition to the terms
of this agreement before downloading, copying, displaying,
performing, distributing or creating derivative works based on this
work or any other Project Gutenberg™ work. The Foundation makes
no representations concerning the copyright status of any work in
any country other than the United States.

1.E. Unless you have removed all references to Project Gutenberg:

1.E.1. The following sentence, with active links to, or other


immediate access to, the full Project Gutenberg™ License must
appear prominently whenever any copy of a Project Gutenberg™
work (any work on which the phrase “Project Gutenberg” appears, or
with which the phrase “Project Gutenberg” is associated) is
accessed, displayed, performed, viewed, copied or distributed:
This eBook is for the use of anyone anywhere in the United
States and most other parts of the world at no cost and with
almost no restrictions whatsoever. You may copy it, give it away
or re-use it under the terms of the Project Gutenberg License
included with this eBook or online at www.gutenberg.org. If you
are not located in the United States, you will have to check the
laws of the country where you are located before using this
eBook.

1.E.2. If an individual Project Gutenberg™ electronic work is derived


from texts not protected by U.S. copyright law (does not contain a
notice indicating that it is posted with permission of the copyright
holder), the work can be copied and distributed to anyone in the
United States without paying any fees or charges. If you are
redistributing or providing access to a work with the phrase “Project
Gutenberg” associated with or appearing on the work, you must
comply either with the requirements of paragraphs 1.E.1 through
1.E.7 or obtain permission for the use of the work and the Project
Gutenberg™ trademark as set forth in paragraphs 1.E.8 or 1.E.9.

1.E.3. If an individual Project Gutenberg™ electronic work is posted


with the permission of the copyright holder, your use and distribution
must comply with both paragraphs 1.E.1 through 1.E.7 and any
additional terms imposed by the copyright holder. Additional terms
will be linked to the Project Gutenberg™ License for all works posted
with the permission of the copyright holder found at the beginning of
this work.

1.E.4. Do not unlink or detach or remove the full Project


Gutenberg™ License terms from this work, or any files containing a
part of this work or any other work associated with Project
Gutenberg™.

1.E.5. Do not copy, display, perform, distribute or redistribute this


electronic work, or any part of this electronic work, without
prominently displaying the sentence set forth in paragraph 1.E.1 with
active links or immediate access to the full terms of the Project
Gutenberg™ License.
1.E.6. You may convert to and distribute this work in any binary,
compressed, marked up, nonproprietary or proprietary form,
including any word processing or hypertext form. However, if you
provide access to or distribute copies of a Project Gutenberg™ work
in a format other than “Plain Vanilla ASCII” or other format used in
the official version posted on the official Project Gutenberg™ website
(www.gutenberg.org), you must, at no additional cost, fee or expense
to the user, provide a copy, a means of exporting a copy, or a means
of obtaining a copy upon request, of the work in its original “Plain
Vanilla ASCII” or other form. Any alternate format must include the
full Project Gutenberg™ License as specified in paragraph 1.E.1.

1.E.7. Do not charge a fee for access to, viewing, displaying,


performing, copying or distributing any Project Gutenberg™ works
unless you comply with paragraph 1.E.8 or 1.E.9.

1.E.8. You may charge a reasonable fee for copies of or providing


access to or distributing Project Gutenberg™ electronic works
provided that:

• You pay a royalty fee of 20% of the gross profits you derive from
the use of Project Gutenberg™ works calculated using the
method you already use to calculate your applicable taxes. The
fee is owed to the owner of the Project Gutenberg™ trademark,
but he has agreed to donate royalties under this paragraph to
the Project Gutenberg Literary Archive Foundation. Royalty
payments must be paid within 60 days following each date on
which you prepare (or are legally required to prepare) your
periodic tax returns. Royalty payments should be clearly marked
as such and sent to the Project Gutenberg Literary Archive
Foundation at the address specified in Section 4, “Information
about donations to the Project Gutenberg Literary Archive
Foundation.”

• You provide a full refund of any money paid by a user who


notifies you in writing (or by e-mail) within 30 days of receipt that
s/he does not agree to the terms of the full Project Gutenberg™
License. You must require such a user to return or destroy all
copies of the works possessed in a physical medium and
discontinue all use of and all access to other copies of Project
Gutenberg™ works.

• You provide, in accordance with paragraph 1.F.3, a full refund of


any money paid for a work or a replacement copy, if a defect in
the electronic work is discovered and reported to you within 90
days of receipt of the work.

• You comply with all other terms of this agreement for free
distribution of Project Gutenberg™ works.

1.E.9. If you wish to charge a fee or distribute a Project Gutenberg™


electronic work or group of works on different terms than are set
forth in this agreement, you must obtain permission in writing from
the Project Gutenberg Literary Archive Foundation, the manager of
the Project Gutenberg™ trademark. Contact the Foundation as set
forth in Section 3 below.

1.F.

1.F.1. Project Gutenberg volunteers and employees expend


considerable effort to identify, do copyright research on, transcribe
and proofread works not protected by U.S. copyright law in creating
the Project Gutenberg™ collection. Despite these efforts, Project
Gutenberg™ electronic works, and the medium on which they may
be stored, may contain “Defects,” such as, but not limited to,
incomplete, inaccurate or corrupt data, transcription errors, a
copyright or other intellectual property infringement, a defective or
damaged disk or other medium, a computer virus, or computer
codes that damage or cannot be read by your equipment.

1.F.2. LIMITED WARRANTY, DISCLAIMER OF DAMAGES - Except


for the “Right of Replacement or Refund” described in paragraph
1.F.3, the Project Gutenberg Literary Archive Foundation, the owner
of the Project Gutenberg™ trademark, and any other party
distributing a Project Gutenberg™ electronic work under this
agreement, disclaim all liability to you for damages, costs and
expenses, including legal fees. YOU AGREE THAT YOU HAVE NO
REMEDIES FOR NEGLIGENCE, STRICT LIABILITY, BREACH OF
WARRANTY OR BREACH OF CONTRACT EXCEPT THOSE
PROVIDED IN PARAGRAPH 1.F.3. YOU AGREE THAT THE
FOUNDATION, THE TRADEMARK OWNER, AND ANY
DISTRIBUTOR UNDER THIS AGREEMENT WILL NOT BE LIABLE
TO YOU FOR ACTUAL, DIRECT, INDIRECT, CONSEQUENTIAL,
PUNITIVE OR INCIDENTAL DAMAGES EVEN IF YOU GIVE
NOTICE OF THE POSSIBILITY OF SUCH DAMAGE.

1.F.3. LIMITED RIGHT OF REPLACEMENT OR REFUND - If you


discover a defect in this electronic work within 90 days of receiving it,
you can receive a refund of the money (if any) you paid for it by
sending a written explanation to the person you received the work
from. If you received the work on a physical medium, you must
return the medium with your written explanation. The person or entity
that provided you with the defective work may elect to provide a
replacement copy in lieu of a refund. If you received the work
electronically, the person or entity providing it to you may choose to
give you a second opportunity to receive the work electronically in
lieu of a refund. If the second copy is also defective, you may
demand a refund in writing without further opportunities to fix the
problem.

1.F.4. Except for the limited right of replacement or refund set forth in
paragraph 1.F.3, this work is provided to you ‘AS-IS’, WITH NO
OTHER WARRANTIES OF ANY KIND, EXPRESS OR IMPLIED,
INCLUDING BUT NOT LIMITED TO WARRANTIES OF
MERCHANTABILITY OR FITNESS FOR ANY PURPOSE.

1.F.5. Some states do not allow disclaimers of certain implied


warranties or the exclusion or limitation of certain types of damages.
If any disclaimer or limitation set forth in this agreement violates the
law of the state applicable to this agreement, the agreement shall be
interpreted to make the maximum disclaimer or limitation permitted
by the applicable state law. The invalidity or unenforceability of any
provision of this agreement shall not void the remaining provisions.

1.F.6. INDEMNITY - You agree to indemnify and hold the


Foundation, the trademark owner, any agent or employee of the
Foundation, anyone providing copies of Project Gutenberg™
electronic works in accordance with this agreement, and any
volunteers associated with the production, promotion and distribution
of Project Gutenberg™ electronic works, harmless from all liability,
costs and expenses, including legal fees, that arise directly or
indirectly from any of the following which you do or cause to occur:
(a) distribution of this or any Project Gutenberg™ work, (b)
alteration, modification, or additions or deletions to any Project
Gutenberg™ work, and (c) any Defect you cause.

Section 2. Information about the Mission of


Project Gutenberg™
Project Gutenberg™ is synonymous with the free distribution of
electronic works in formats readable by the widest variety of
computers including obsolete, old, middle-aged and new computers.
It exists because of the efforts of hundreds of volunteers and
donations from people in all walks of life.

Volunteers and financial support to provide volunteers with the


assistance they need are critical to reaching Project Gutenberg™’s
goals and ensuring that the Project Gutenberg™ collection will
remain freely available for generations to come. In 2001, the Project
Gutenberg Literary Archive Foundation was created to provide a
secure and permanent future for Project Gutenberg™ and future
generations. To learn more about the Project Gutenberg Literary
Archive Foundation and how your efforts and donations can help,
see Sections 3 and 4 and the Foundation information page at
www.gutenberg.org.
Section 3. Information about the Project
Gutenberg Literary Archive Foundation
The Project Gutenberg Literary Archive Foundation is a non-profit
501(c)(3) educational corporation organized under the laws of the
state of Mississippi and granted tax exempt status by the Internal
Revenue Service. The Foundation’s EIN or federal tax identification
number is 64-6221541. Contributions to the Project Gutenberg
Literary Archive Foundation are tax deductible to the full extent
permitted by U.S. federal laws and your state’s laws.

The Foundation’s business office is located at 809 North 1500 West,


Salt Lake City, UT 84116, (801) 596-1887. Email contact links and up
to date contact information can be found at the Foundation’s website
and official page at www.gutenberg.org/contact

Section 4. Information about Donations to


the Project Gutenberg Literary Archive
Foundation
Project Gutenberg™ depends upon and cannot survive without
widespread public support and donations to carry out its mission of
increasing the number of public domain and licensed works that can
be freely distributed in machine-readable form accessible by the
widest array of equipment including outdated equipment. Many small
donations ($1 to $5,000) are particularly important to maintaining tax
exempt status with the IRS.

The Foundation is committed to complying with the laws regulating


charities and charitable donations in all 50 states of the United
States. Compliance requirements are not uniform and it takes a
considerable effort, much paperwork and many fees to meet and
keep up with these requirements. We do not solicit donations in
locations where we have not received written confirmation of
compliance. To SEND DONATIONS or determine the status of
compliance for any particular state visit www.gutenberg.org/donate.

While we cannot and do not solicit contributions from states where


we have not met the solicitation requirements, we know of no
prohibition against accepting unsolicited donations from donors in
such states who approach us with offers to donate.

International donations are gratefully accepted, but we cannot make


any statements concerning tax treatment of donations received from
outside the United States. U.S. laws alone swamp our small staff.

Please check the Project Gutenberg web pages for current donation
methods and addresses. Donations are accepted in a number of
other ways including checks, online payments and credit card
donations. To donate, please visit: www.gutenberg.org/donate.

Section 5. General Information About Project


Gutenberg™ electronic works
Professor Michael S. Hart was the originator of the Project
Gutenberg™ concept of a library of electronic works that could be
freely shared with anyone. For forty years, he produced and
distributed Project Gutenberg™ eBooks with only a loose network of
volunteer support.

Project Gutenberg™ eBooks are often created from several printed


editions, all of which are confirmed as not protected by copyright in
the U.S. unless a copyright notice is included. Thus, we do not
necessarily keep eBooks in compliance with any particular paper
edition.

Most people start at our website which has the main PG search
facility: www.gutenberg.org.

This website includes information about Project Gutenberg™,


including how to make donations to the Project Gutenberg Literary
Archive Foundation, how to help produce our new eBooks, and how
to subscribe to our email newsletter to hear about new eBooks.

You might also like