Chemours-ISCEON-39TC-MSDS-v3 (1)

SAFETY DATA SHEET according to Regulation (EC) No 1907/2006
and 453/2010
DuPont™ ISCEON® 39TC® (R-423A) refrigerant

Version 3.0
Revision Date 22.11.2012 Ref. 130000027358
This SDS adheres to the standards and regulatory requirements of Great Britain and may not meet the regulatory
requirements in other countries.
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1. Product identifier
Product name : DuPont™ ISCEON® 39TC® (R-423A) refrigerant
Types : ASHRAE Refrigerant number designation: R-423A
Synonyms : R-423A
ISCEON® 39TC®
1.2. Relevant identified uses of the substance or mixture and uses advised against
Use of the Substance/Mixture Refrigerant
1.3. Details of the supplier of the safety data sheet
Company : Du Pont de Nemours (Nederland) B.V.

Baanhoekweg 22
NL-3313 LA Dordrecht
Netherlands
Telephone : +31-78-630.1011
E-mail address : sds-support@che.dupont.com
1.4. Emergency telephone number
Emergency telephone number : +44-(0)8456-006.640
SECTION 2: Hazards identification

2.1. Classification of the substance or mixture
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.
2.2. Label elements
Special labelling of certain Contains: 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-Heptafluoropropane /

substances and mixtures Contains fluorinated greenhouse gas covered by the Kyoto Protocol., HFC-
134a, HFC-227ea
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.
2.3. Other hazards
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Vapours are heavier than air and can cause suffocation by reducing oxygen available for breathing.
Rapid evaporation of the liquid may cause frostbite.
Misuse or intentional inhalation abuse may cause death without warning symptoms, due to cardiac effects.
May cause cardiac arrhythmia.
SECTION 3: Composition/information on ingredients
3.1. Substances
not applicable
3.2. Mixtures
Registration number Classification Classification according Concentration
according Directive Regulation 1272/2008 (CLP)
67/548/EEC
1,1,1,2-Tetrafluoroethane (CAS-No.811-97-2) (EC-No.212-377-0)

01-2119459374-33 Press. Gas H280 52.5 %
1,1,1,2,3,3,3-Heptafluoropropane (CAS-No.431-89-0) (EC-No.207-079-2)

01-2119485489-18 Press. Gas H280 47.5 %
The above products are REACH compliant; Registration number(s) may not be provided because substance(s)
are exempted, not yet registered under REACH or are registered under another regulatory process (biocide uses,
plant protection products), etc.
For the full text of the H-Statements mentioned in this Section, see Section 16.
SECTION 4: First aid measures

4.1. Description of first aid measures
General advice : If unconscious place in recovery position and seek medical advice. Never give
anything by mouth to an unconscious person. If breathing is irregular or
stopped, administer artificial respiration.
: First aider needs to protect himself.
: If symptoms persist, call a physician.
Inhalation : Remove from exposure, lie down. Move to fresh air. Keep patient warm and at
rest. Artificial respiration and/or oxygen may be necessary. Consult a
physician.
Skin contact : Take off contaminated clothing and shoes immediately. Flush area with
lukewarm water. Do not use hot water. If frostbite has occurred, call a
physician.
Eye contact : Hold eyelids apart and flush eyes with plenty of water for at least 15 minutes.
Get medical attention.
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Ingestion : Is not considered a potential route of exposure.
4.2. Most important symptoms and effects, both acute and delayed
Symptoms : Misuse or intentional inhalation abuse may cause death without warning
symptoms, due to cardiac effects., Other symptoms potentially related to
misuse or inhalation abuse are:, Anaesthetic effects, Light-headedness,
dizziness, confusion, incoordination, drowsiness, or unconsciousness, irregular
heartbeat with a strange sensation in the chest, heart thumping, apprehension,
feeling of fainting, dizziness or weakness
: Skin contact may provoke the following symptoms:, Frostbite, Irritation,

Discomfort, Itching, Redness, Swelling of tissue
: Eye contact may provoke the following symptoms:, Frostbite, Irritation, Tearing,
redness, or discomfort.
4.3. Indication of any immediate medical attention and special treatment needed
Treatment : Do not give adrenaline or similar drugs.
SECTION 5: Firefighting measures
5.1. Extinguishing media
Suitable extinguishing media : Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2. Special hazards arising from the substance or mixture
Specific hazards during : Pressure build-up. Fire or intense heat may cause violent rupture of packages.
firefighting
: Hazardous thermal decomposition products:
: Carbon oxides
: Hydrogen fluoride
: Fluorinated compounds
: Exposure to decomposition products may be a hazard to health.
5.3. Advice for firefighters
Special protective equipment : In the event of fire, wear self-contained breathing apparatus. Use personal
for firefighters protective equipment. Wear neoprene gloves during cleaning up work after a
fire.
Further information : Cool containers / tanks with water spray.
SECTION 6: Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures
Personal precautions : Evacuate personnel to safe areas. Ventilate area, especially low or enclosed
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places where heavy vapours might collect. Refer to protective measures listed
in sections 7 and 8.
6.2. Environmental precautions
Environmental precautions : Should not be released into the environment.
In accordance with local and national regulations.
6.3. Methods and materials for containment and cleaning up
Methods for cleaning up : Evaporates.
6.4. Reference to other sections
For disposal instructions see section 13.
SECTION 7: Handling and storage

7.1. Precautions for safe handling
Advice on safe handling : Avoid breathing vapours or mist. Avoid contact with skin, eyes and clothing.
Provide sufficient air exchange and/or exhaust in work rooms. For personal
protection see section 8.
Vapours are heavier than air and may spread along floors.
Advice on protection : The product is not flammable in air under ambient conditions of temperature
against fire and explosion and pressure. When pressurised with air or oxygen, the mixture may become
flammable. Certain mixtures of HCFCs or HFCs with chlorine may become
flammable or reactive under certain conditions.
7.2. Conditions for safe storage, including any incompatibilities
Requirements for storage : Do not drag, slide or roll cylinders. Never attempt to lift cylinder by its cap. Use
areas and containers a check valve or trap in the discharge line to prevent hazardous back flow into
the cylinder. Keep at temperature not exceeding 52°C. Keep containers tightly
closed in a dry, cool and well-ventilated place. Protect from contamination.
Protect cylinders from damage. Keep away from direct sunlight. Store only in
approved containers.
Advice on common storage : No materials to be especially mentioned.
For further information see Section 10 of the safety data sheet.
Storage temperature : < 52 °C
7.3. Specific end use(s)
no data available
SECTION 8: Exposure controls/personal protection
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8.1. Control parameters
If sub-section is empty then no values are applicable.
Components with workplace control parameters

Type Control Update Basis Remarks
Form of exposure parameters
1,1,1,2-Tetrafluoroethane (CAS-No. 811-97-2)

TWA 4,240 mg/m3 2007 EH40 WEL
1,000 ppm
Derived No Effect Level (DNEL)
● 1,1,1,2-Tetrafluoroethane : Type of Application (Use): Workers

Exposure routes: Inhalation
Health Effect: Chronic effects, Systemic toxicity
Value: 13936 mg/m3
: Type of Application (Use): Consumers

Value: 2476 mg/m3
● 1,1,1,2,3,3,3- : Type of Application (Use): Workers

Heptafluoropropane Exposure routes: Inhalation
Value: 61279 mg/m3
: Type of Application (Use): Consumers

Value: 6533 mg/m3
Predicted No Effect Concentration (PNEC)
● 1,1,1,2-Tetrafluoroethane : Value: 0.1 mg/l

Compartment: Fresh water
: Value: 0.01 mg/l

Compartment: Marine water
: Value: 1 mg/l
Compartment: Water
Remarks: Intermittent use/release
: Value: 0.75 mg/kg dry weight (d.w.)

Compartment: Fresh water sediment
: Value: 73 mg/l
Compartment: Water
Remarks: Sewage treatment plants
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● 1,1,1,2,3,3,3- : Value: 0.1 mg/l

Heptafluoropropane Compartment: Fresh water
: Value: 1 mg/l
Compartment: Water
Remarks: Intermittent use/release
: Value: 1.3 mg/kg

Compartment: Fresh water sediment
: Value: 1.73 mg/kg

Compartment: Water
Remarks: Sewage treatment plants
8.2. Exposure controls
Engineering measures : Ensure adequate ventilation, especially in confined areas. Local exhaust should
be used when large amounts are released.
Eye protection : Wear safety glasses or coverall chemical splash goggles.

Eye protection complying with EN 166.
or
ANSI Z87.1
Additionally wear a face shield where the possibility exists for face contact due
to splashing, spraying or airborne contact with this material.
Hand protection : Material: Leather gloves

The suitability for a specific workplace should be discussed with the producers
of the protective gloves.
: Material: Low temperature resistant gloves
:
Protective gloves complying with EN 374. or US OSHA guidelines
:
The choice of an appropriate glove does not only depend on its material but also
on other quality features and is different from one producer to the other. Please
observe the instructions regarding permeability and breakthrough time which
are provided by the supplier of the gloves. Also take into consideration the
specific local conditions under which the product is used, such as the danger of
cuts, abrasion, and the contact time.
Skin and body protection : Wear suitable protective equipment. Wear as appropriate: impervious clothing
Protective measures : Self-contained breathing apparatus (SCBA) is required if a large release occurs.
The type of protective equipment must be selected according to the
concentration and amount of the substance at the specific workplace.
Hygiene measures : Handle in accordance with good industrial hygiene and safety practice.
Respiratory protection : For rescue and maintenance work in storage tanks use self-contained breathing
apparatus. Vapours are heavier than air and can cause suffocation by reducing
oxygen available for breathing. Respiratory protection complying with EN 137.
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SECTION 9: Physical and chemical properties
9.1. Information on basic physical and chemical properties
Form : Liquefied gas
Colour : colourless
Odour : slight, ether-like
pH : neutral
Boiling point/boiling range : ca. -25 °C at 1,013 hPa
Flash point : does not flash
Upper explosion limit/ upper : not applicable

flammability limit
Vapour pressure : ca. 6,400 hPa at 25 °C
Relative density : 1.28 at 25 °C

9.2. Other information
no data available
SECTION 10: Stability and reactivity
10.1. Reactivity : Decomposes on heating.
10.2. Chemical stability : The product is chemically stable.
10.3. Possibility of : Polymerization will not occur. Stable under recommended storage conditions.
hazardous reactions
10.4. Conditions to avoid : Avoid open flames and high temperatures. The product is not flammable in air
under ambient conditions of temperature and pressure. When pressurised with
air or oxygen, the mixture may become flammable. Certain mixtures of HCFCs
or HFCs with chlorine may become flammable or reactive under certain
conditions. Pressurized container: Do not pierce or burn, even after use. Keep
at temperature not exceeding 52°C.
10.5. Incompatible materials : Alkali metals

Alkaline earth metals
Powdered metals
Powdered metal salts
10.6. Hazardous : Hazardous thermal decomposition products may include:

decomposition products Hydrogen fluoride
Carbon oxides
Fluorocarbons
Carbonyl fluoride
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SECTION 11: Toxicological information
11.1. Information on toxicological effects
Acute oral toxicity
• 1,1,1,2,3,3,3-Heptafluoropropane
not applicable
Acute inhalation toxicity
• 1,1,1,2-Tetrafluoroethane
LC50 / 4 h rat :567000 ppm
Low Observed Adverse Effect Concentration (LOAEC) / dog :75000 ppm

Cardiac sensitization
No Observed Adverse Effect Concentration (NOAEC) / dog :50000 ppm

LC50 / 4 h rat :> 788698 ppm
Low Observed Adverse Effect Concentration (LOAEC) / dog :105000 ppm

No Observed Adverse Effect Concentration (NOAEC) / dog :90000 ppm
Acute dermal toxicity
not applicable
Skin irritation
rabbit
Classification: Not classified as irritant
Result: slight irritation
Not expected to cause skin irritation based on expert review of the properties of the substance.
human
Result: No skin irritation
Not tested on animals
Result: No skin irritation
Not expected to cause skin irritation based on expert review of the properties of the substance.
Eye irritation
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rabbit
Result: slight irritation
Not expected to cause eye irritation based on expert review of the properties of the substance.
human
Result: No eye irritation
Result: No eye irritation
Not expected to cause eye irritation based on expert review of the properties of the substance.
Sensitisation
guinea pig
Classification: Not a skin sensitizer.
Result: Did not cause sensitization on laboratory animals.
Not expected to cause sensitization based on expert review of the properties of the substance.
Did not cause sensitization on laboratory animals. There are no reports of human respiratory sensitization.
Classification: Not a skin sensitizer.
Result: Does not cause skin sensitization.
Not expected to cause sensitization based on expert review of the properties of the substance.
Did not cause sensitization on laboratory animals. There are no reports of human respiratory sensitization.
Repeated dose toxicity
Inhalation rat
No toxicologically significant effects were found.
Inhalation rat
No toxicologically significant effects were found.
Mutagenicity assessment
Animal testing did not show any mutagenic effects. Tests on bacterial or mammalian cell cultures did not
show mutagenic effects.
Animal testing did not show any mutagenic effects. Tests on bacterial or mammalian cell cultures did not
show mutagenic effects.
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Carcinogenicity assessment
Not classifiable as a human carcinogen.
Not classifiable as a human carcinogen.
Toxicity to reproduction assessment
No toxicity to reproduction
No toxicity to reproduction
Further information
Avoid skin contact with leaking liquid (danger of frostbite).
SECTION 12: Ecological information
12.1. Toxicity
Toxicity to fish
LC50 / 96 h / Oncorhynchus mykiss (rainbow trout): 450 mg/l
LC50 / 96 h / Danio rerio (zebra fish): > 200 mg/l
Information given is based on data obtained from similar substances.
LC50 / 96 h / Oncorhynchus mykiss (rainbow trout): > 81.8 mg/l

Toxicity to aquatic plants
EC50 / 72 h / Algae: > 118 mg/l
EC50 / 72 h / Pseudokirchneriella subcapitata: > 114 mg/l
Toxicity to aquatic invertebrates
EC50 / 48 h / Daphnia magna (Water flea): 980 mg/l
EC50 / 48 h / Daphnia magna (Water flea): > 200 mg/l
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12.2. Persistence and degradability
Biodegradability
/ 28 d
Biodegradation: 3 %
Not readily biodegradable.
aerobic 8.49 mg/l / 28 d
Biodegradation: 1 %
Method: OECD Test Guideline 301
aerobic 17.4 mg/l / 28 d
Biodegradation: 5 %
Method: OECD Test Guideline 301
12.3. Bioaccumulative potential
Bioaccumulation
Bioaccumulation is unlikely.
12.4. Mobility in soil
no data available
12.5. Results of PBT and vPvB assessment
no data available
12.6. Other adverse effects
Ozone depletion potential
Global warming potential (GWP)
2280
Additional ecological information
IPCC - AR4 (Fourth Assessment Report of the Intergovernmental Panel on Climate Change) - 2007
SECTION 13: Disposal considerations

13.1. Waste treatment methods
Product : Can be used after re-conditioning. If re-conditioning is not practicable, dispose

of in compliance with local regulations.
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Contaminated packaging : Empty pressure vessels should be returned to the supplier.
If recycling is not practicable, dispose of in compliance with local regulations.
SECTION 14: Transport information

ADR
14.1. UN number: 1078
14.2. UN proper shipping name: Refrigerant gas, n.o.s. (1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-
Heptafluoropropane)
14.3. Transport hazard class(es): 2
14.4. Packing group: not applicable
14.5. Environmental hazards: For further information see Section 12.
14.6. Special precautions for user:
Tunnel restriction code: (C/E)
IATA_C
14.1. UN number: 1078
Heptafluoropropane)
14.3. Transport hazard class(es): 2.2
14.5. Environmental hazards : For further information see Section 12.
no data available
IMDG
14.1. UN number: 1078
Heptafluoropropane)
14.3. Transport hazard class(es): 2.2
14.5. Environmental hazards : For further information see Section 12.
no data available
14.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
not applicable
SECTION 15: Regulatory information

15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
Other regulations : Take note of Directive 98/24/EC on the protection of the health and safety of
workers from the risks related to chemical agents at work.
15.2. Chemical Safety Assessment
Chemical Safety Assessments have been carried out for these substances.
SECTION 16: Other information

Full text of H-Statements referred to under section 3.
H280 Contains gas under pressure; may explode if heated.

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Further information
®
DuPont's registered trademark, Before use read DuPont's safety information., For further information contact the
local DuPont office or DuPont's nominated distributors.
Significant change from previous version is denoted with a double bar.
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at
the date of its publication. The information given is designed only as a guide for safe handling, use, processing,
storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The
above information relates only to the specific material(s) designated herein and may not be valid for such material(s)
used in combination with any other materials or in any process or if the material is altered or processed, unless
specified in the text.
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SAFETY DATA SHEET according to Regulation (EC) No 1907/2006

DuPont™ ISCEON® 39TC® (R-423A) refrigerant

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1. Product identifier

Product name : DuPont™ ISCEON® 39TC® (R-423A) refrigerant

Types : ASHRAE Refrigerant number designation: R-423A

Use of the Substance/Mixture Refrigerant

1.3. Details of the supplier of the safety data sheet

Company : Du Pont de Nemours (Nederland) B.V.

E-mail address : sds-support@che.dupont.com

1.4. Emergency telephone number

Emergency telephone number : +44-(0)8456-006.640

SECTION 2: Hazards identification

Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.

2.2. Label elements

Special labelling of certain Contains: 1,1,1,2-Tetrafluoroethane, 1,1,1,2,3,3,3-Heptafluoropropane /

Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.

2.3. Other hazards

DuPont™ ISCEON® 39TC® (R-423A) refrigerant

SECTION 3: Composition/information on ingredients

1,1,1,2-Tetrafluoroethane (CAS-No.811-97-2) (EC-No.212-377-0)

1,1,1,2,3,3,3-Heptafluoropropane (CAS-No.431-89-0) (EC-No.207-079-2)

SECTION 4: First aid measures

: First aider needs to protect himself.

: If symptoms persist, call a physician.

DuPont™ ISCEON® 39TC® (R-423A) refrigerant

Ingestion : Is not considered a potential route of exposure.

: Skin contact may provoke the following symptoms:, Frostbite, Irritation,

Treatment : Do not give adrenaline or similar drugs.

SECTION 5: Firefighting measures

5.1. Extinguishing media

: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2. Special hazards arising from the substance or mixture

5.3. Advice for firefighters

Further information : Cool containers / tanks with water spray.

SECTION 6: Accidental release measures

DuPont™ ISCEON® 39TC® (R-423A) refrigerant

6.2. Environmental precautions

Environmental precautions : Should not be released into the environment.

In accordance with local and national regulations.

6.3. Methods and materials for containment and cleaning up

Methods for cleaning up : Evaporates.

6.4. Reference to other sections

For disposal instructions see section 13.

SECTION 7: Handling and storage

7.2. Conditions for safe storage, including any incompatibilities

Advice on common storage : No materials to be especially mentioned.

For further information see Section 10 of the safety data sheet.

Storage temperature : < 52 °C

7.3. Specific end use(s)

SECTION 8: Exposure controls/personal protection

DuPont™ ISCEON® 39TC® (R-423A) refrigerant

8.1. Control parameters

If sub-section is empty then no values are applicable.

Components with workplace control parameters

1,1,1,2-Tetrafluoroethane (CAS-No. 811-97-2)

Derived No Effect Level (DNEL)

● 1,1,1,2-Tetrafluoroethane : Type of Application (Use): Workers

: Type of Application (Use): Consumers

● 1,1,1,2,3,3,3- : Type of Application (Use): Workers

: Type of Application (Use): Consumers

Predicted No Effect Concentration (PNEC)

● 1,1,1,2-Tetrafluoroethane : Value: 0.1 mg/l

: Value: 0.01 mg/l