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    Dược lý lâm sàng (1)

    Uploaded by

    Anh Minh Nguyen Vo

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    © All Rights Reserved
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    TRUONG DH ¥ DI CAN LBMDUGELY. DUGCLAN oes en aig NA aa acon Diituomg deh VAS S00 mg/ vitamin D 400 TU a0 LS m ng 72K Ch abT {Wo trong erm anh gn Le én pron hay ‘wong ee eee cogornaer eee Peel oy vi omg. fwong ky xay r2 bén ngodi co thé vA tung tic dy. ruben tong co thd 1b. Chi cd tg ky mdi dun dén didu bit Ioi Ki phi ‘hop thude Thong shige tne mi vk tani viene Troms be tnt al ann be hed Scent ye eke te TRAM ee [Dn 9 pict | wi oe. 238 EAGe nes tata cruised sgn ‘ghy 31/12/2020 “Hudng dim there hign gel dg hog nro ah Te aN Mn NE ip hoy i tg ayn sang dung wing i hing sinh cO sinh kb dg dung wg cao Ge thetic arte utng tiem (do dng nap ta -tSeten) sinh ¢6 sinh Kb dung dung, ung thip aig ida tip hon dg tiem (how ns ata gy cr rime TRAM3 - sone ian 7] yr ci du ding Cau 32, Nhigm vy cia HG thing Canh gle ‘Durge tai Vigt Nam: ‘ ‘a. Phat hién va g6p phin gidm thiéu cfc sai s6t trong ké dom, sao chép y Kgnh, cp phat va str EL ay cin ao in guy 0 vi qin cundatte ape bog ot tcc ve db win ‘Cau 37. Thude oé tic dung lim ting coving the quan audi: aa a.Trimebutin dltoprid .Sulpitid Tat ci déu ding ‘Cu 38. Cin phai diin bénh niin didu gi khi sir ding sucralfat a8 aidu tri bénh trho nguye ‘dg diy — thye quan: a ‘Ciu 43. Theo Hurimg din Quéc gia vé Canh ‘hie Dirge (2021), khi xy ra pha tng o6 hat ‘nghiém trong gy ti vong hose de doa tinh ‘mang, thoi gian dé git bio céo tinh tir thot ‘xy ra phi ing iz a Trong vong 3 ney lim vige rong ving 7 ngiy lim viee ¢.Trong ving 15 ngiy lim vige 4.C6 thé ip hop gt hing thing, ude ney ‘ming Sci thing ket (Cin 4, Ngo thing tin thude 6d in c¥y a0 cin. Chenguyta wt Chena hin hye og 4G Hn ah ml eco quan hfe cna cn ma F 1 King din bp se e shidsaie Tht ek ds St Pht igw no dr iy KHONG DUNG auinolon dye ot me yeu 18 ng co ey pit {ince ching VK Gr) Hing bg ‘bTrenln sng pt} AUCINOC > 30 cba sch hi fuoroeialon age tm fre PRIPD ae tia oda 0% hn ng ong it em Bees Tae pee eee. Warr natcoaister Pee ern TEES, Sabicea biecaea bb. 6 Nauta the co tak nesses picetonn pee oe ite eet, Pier eee eS cecakas ‘> PHU LUC: Dae ing sah ign ‘es sin PA LUC: Ts exe nh ng bet 80 ob Sept ag ih oo ene ng “4 PHU LUC, Dank me Rpg sion chyna tia tnpeasang debs wg (PO) ‘cau $3, Theo I Tim mph bee Qube ga Viet "Nam GOB) thu tage Smhm the chin I tuba sou ki ngung corticoid b. 2 4tuin sau khi ngung conicoid , > | thing sau Khi ngung coricoid 3 thing sau Ki ngumg contcoid uS. Myc tifa kiém sodt during huyét cho Adi thio atng type 20 ngudi cao tubl tink treng ste Kkhde trung binh theo ADA2020 IA: 1. Glucose huyét mao mach tre tn < 160mp/dL bb, Glucose huydt mao mach sau &n 80 -130mg/db ‘cOlucose huye mao mach tude ngi 80-130me/dL @rrnie cr co cas gona fu 6. Chga myc tu HbALe theo hutng nghitm ‘EH (6%) bp dyng eho bfah nbn di thio dudug, theo ADA2020: a fe tul thd dit, ft ong Ive sing be. Nhidu béah nog mie kém HQC KY I ui VAM HOC 2021-2022 WYLAM SANG MABE: LOD Kes fe bean 61 situ nam ‘Thdi gian mic bénh di théo dising _ (@ New carte dang hay td, kek nig tat cae ih mhdin Gai Cau 7, Logi inst itn khési tr] eho bént {ho dvdng type 2 theo Khuyén cdo ADA2020 la: onstin gular ene slaraia B:isuinpremid Dinsiinaspart Glu. Nguyéa te sirdyng ahr gluco-corticoid: hg ding corto Ki e6 suy 6 hép ning 1 Ding conicid ko di >2 thing kh ngung Kang cin git Qc chem bio gitp gn log corticoid phi hop véi chi dink iu 9. Chon corticoid dé digu trj hoi chémg than bw nguyén phat: Fudrocorison @ Prednisoton Birscvivn 1. Bethamethason a 10, Mots hinh thie lién quan dén sai st trong sr dyng thube: a. Sa du ding «. Sai thei diém ding 8. Sai ding ding it ch du ding Ce 11. Cin gid dye a «Phat ign bin of bt loi xdy a trong qué tinh ding 1 . Bia gi mdi tin quan gia bidn of thule dugeding = 6. Phong tro bin bb Ri ti i nee SR dng be “du 12. Nhigm vy cia Hé théng Cink ie tpl Vige Nam: pe — 4 Pt higo vA gp ph gdm thu che sis tron 8 don, sao chép y ln, cdp phit vast dong tobe Feet eid neuy cova quin ty nguy co itn quan dén “Truydnthéng ob hi Y Gusts itu qua fc vin 48 anton thade ‘TRAM2 (Clu 13. Sipxép theo this ty vd mgt thd gian ede Durie trong quy triah host dng cia be thong Ch gti drge tai Vigt Nam lit 4. Dinh gid nguy co-< Truydn thing < Ra quyét inh ean thigp 50% LDL-« kh ding lidu >20me/ngay fu 28. Chién re tm intr cde nguds thong tin thube trong thye hah di tri? a. Nén tim tir nguin efp | trudc, sau 5 din efp 2 vi ‘cubi cling méi cdp 3 , Néa tim th nguéa elp 2 tude, su 45 din ebp3 vi i cing mdi cp | 2 Xen tm tr nguba el 3 trvbe, sau db dén cp 2 vi i cing msi ep 1 4. Nén tim od 3ngebn cing lie (Cin 29. Khitrs eu trong the thube tron website DRUGS.COM, théng tin ban 5 thé tra eiru duoe: (Mie 69 trong th; (Il) Che nghién edu chimg minh tong te; (IT) Corehé teong the; (1V) Hg ‘qua teomg the? &. Chi() ding be) vi V) ding <.(), (tH) va (IV) ing {n.ai) tev) ding 0. Trong Khuyéa cio vé Chin dodn vi Didu ing huyEt dp nim 2018 cia Hpi Tim Mych hoe Quie gia Vigt Nam, mie ching ei B cho bit dr uo tet & Nhids nghien ca lim sing aglu nhién hoje ee aa cass Setaeene ¢. Cie nghién efru nbd, ede nghién ciu hdi ciru ting thugn céc chuyén gi@ " ete co 7 alb en dau nhs ce ae ee sree Aron aA ra) evo. Ketek eo ‘T-score la - 0,94. Két lon ld: Tygon Weeping 1b Giim mat d6 xuong_ — &Bénh long xuong ning ‘Chu 32, Mot bémb nhfin nit 70 tudi, bj gay xem chu va céchi's6 T BMD ~2,6 ¢ 66 xuong dil va— 2.1 é xuong sing, nbgn dja! b. Gidm mgt 4 xuong & xuoms Ati gcotng nuns ume @ ‘ong xuong ning 6 xuong Abi a 33. Cb mt dom thud, bso gdm phosphatugel vi levofloxacin: néu bgah abin uéng dng thet hal tude trén,e6 thé lam gidm eke dyng eda clprofioxacia, do: 1.Clm Gng enzym chuybn héa tube Bam yap cin ich vi Gin két canh tranh trén protein huyét trong 'g0 phic n6i chelat ben vig, cin te hip tha au 3, Xe phi Marker chu chuyéa seg, dah gi dap emg didu tri sau 3-6 thang didu tr ip chin doin fodag xuomg «Dah gid tinh tring bah lotng xuong 4. Phit ign nguyén nhdn gly Lodng sarong thé pht Cfu 3S. Khi mlo chn chi dink do raft 45 xuvog, ‘bing phirong php hip phy fia X ning ling kép? ‘a. Phy nd'> 65 tubi hoje nam gidi> 70 te ®. Phy nd <65 tdi dd min kinh vA nam gigi 50 —69 tudi 6 ede yu nguy og , Gidn si dit tr gen beh nhdn dang duge ida tr} eh otag avong Gia iu 36, Trong dtu tr odag rung, thude nto sau Aly vic the dng ting to rung view 6 the dyn, tteché hiy rong 2. Teriparatid Strontium ranelat *. Acid Zoledronic 4. Calcitonin TRAM 4 (Cin 37. Nhém thube SGLT2i (empagliNozin, sz, eapagliozin) dye wu ies eb inh trong trwime hyp 4 Di thio ding tzpe? bién chime tn thuone diy rit Di thio duimg type? bién ching suy thin ning thio dst type2 cb binhthgn manhole uy 4, Déithio duimng type 2 big chimg nhifm ting bin chin (Clu 38. Thue dite tr béah tro neuye da diy — {hye quia nio sau diy ckn thn trong kil ding che bah nbin sy tin sung huyEt vd soy th Suc . Dompeidon Oren 3.topta 39. Phavog php lim sing nh su diy dirge em lie chute ving di chin doin bak tro nguge dy dy ~ the quan: ENGI soi thy gun O. Xeqang thpe quia «Do tp ie co vong thgequtn dud FH hve guin 24 gio fab. Thad che dng lira tog trcongye covong thvequin dv: Ss Metaelpranid rpeidon bttopaa or ch du ding (Caw $1. Dé tng niu qua ait tr bfnh tho gue dx day hye qudn,lrdag dfn fa ah ‘king thobe Khdng cid (antacid) tio th ddan Nay tude Ki te @ie sau 3 Ban chinh vA mt Bat: gi cc. Ubng mot lin duy nhit trade khi ngs 6.30 - 60 phir trvoe ki aa sing (Chu 42 Kh bfah nhge €6 ed tigu chang adn hinh (7 néng, tré), bénh nbn cé thé duge chin oan bing cich dit tr thir bing thube Ge bom proton v6i itu ghp d6i trong that a. Mot tun, ¢ Batuin i tun 4. BBn twin iu 43, Theo Quyét djah s6 5631/QD-BYT ngay (31/12/2020 “Huong din thyc hi¢n quan ly si yng kbdng sink trong bg via” cia BOY «, lehdng sinh NHOM 1 Sp dyng cho chuyén tr 9g tiem truyen sang dtm ubng Bs hing sinh c6 sinh Kh dyng duome wbngeao 3) hp th tv dang nap td i tong ty Tit duengiigm sang sinh 06 sinh kha dung duémg ubng thd Pe ‘roar hung 6 thé bit tr bing wang lid siah vbr Lee sic inh ka dng dng ng coo (790%) nhung co Lecce ot a - * Ceres em (do ung ep eon Ke bes ery ‘sinh khd dung dude wong thip hon va ligu 16i 4a thdp hon dung tiém ‘Cau 14, Mot bah nhdin nif 68 tudi, 6 chi s6 T Sui 24 ecb suong dui vi2-1 8 xromg bog, nnd dn ato sau hy 960g ‘a. BMD binh thydng 8 xuomg 01 fim mo xuong © xu oargnume oxceng@ CL Lot ong ng Ontong iw 4s: Cie ngutn hag habe inch i bi tthe dung thar Kho trone ‘() MIMS; (1D) VIDAL; (11) Te hung dia Np Dune dfn Vigt Nam? a sirdung th a. Chi () ding (va (i aing 1, At) vi (I) eng (, (UD, (UD va 0) ding (Chu 46. BE ting higu qua didu ti trto nguge da day —thye quia, nén udog omeprazol vio thi dite: 2. Nhal trade kh ung b.Ubng vio thor dim 1 sau khi an ¢. Uéeg mgtlln duy nhdt rude khi nga (Ging vio Ide 30 phi — 66 hit sre ki An sng Clu 47. C6 mgt dom thube bao gm: ciprofloxacin me emetiy (mets, Ki bnh nbin ube adn u ube trén, sE Lim glim hip thu ciprofloxacin do: . é Tao phe lam giém hp tha thube in tro eo ge Lam gidm hp thu thabe im thd gin lam Bing dp dy lm gi oe °8. da dy lim gidm hdp thu 4: Lm thay sp td iy ‘Cau 48. C6 mgt don thude, bao gbm: clopidogrel YBoneprazol . Kh binh nbdn ung dng thot co bj gidm tac dyng ciia clopidogrel, Meet enzym chuyén héa thude CYP2C19 ‘ing enzym chuyén hoa thube C’ ¢-Tpo phée lim thube khéng hip thu ee 4, Lam tings toh qua ha cia cc tube dng ching peo Sia VME omeprazole kéo dai eb thé say diy: NSE itamin Bie Min 86 inPP cheung scant romn one man kind thedng tn 8. Dit D7 ubre G DB +b Débt = xubng LA- LS trés xu Canney eto salag eI Bov ache theo avons GR “Touprofen~ Warfarin” dng tht "Ung nguy c xudt hay Ih dr To tongue garecey aa eve 20 ToNg he trong ran pin Kd rn prten hast Gee Maes the wrong tanh gin ht ten 4. Ibuprofen pty can edhdp Gs Weck (Ciiu 52, Mt dow thabe gon c6:"Manlox vA Isoniazid, khi uéng dng thoi xay ra tuong the thuée ld giim hp thu isoniazid, 1a do: 4. Tang di that isoniazid qua éng thin JCenh tanh gin ket ten protein huyé tong, tng pH da diy ‘Lim gidm pH do diy Chu 3. Theo hung dn i dg hg sinh ban ‘anh kém theo Quyét djnh s6 700QD-BYT ngay 02/03/2015, nguyen the si dyag khang sink gm eo: a 12Neuyinieey thé c.6 Nguyen tie cvthd Neuen tic cuthe dd Nguyéa te ev the iu 54. Cie nguyén tic sirdyng khing sinh theo ‘dim sirdyng khdng sinh, ban hah kem theo Quyét ojnn 36. 708/Q0-BYT ngiy 021092015 cin BO NGOAI TRU a Lys chon khing sis va liu bxong b. Sitdung kg sinh dy phng Sir dung Khiag sink didu tj theo kinhnghitm ng nei sy 8 Kndng Kndag sinh fu 85, Suedyng Meiroaidazole cho nhimg ng “Gang wing regu c6 thé dura én tink trang non mea, ‘hu, &6 mbt, do ea ché: ‘Metronidizol ic ché enzyme aleol dehydrogenase by. Rugu gly Geché enzym Cytochrome Paso gu Hy cam ing enzym Cyiochrome Paso {evoridacol de ché enzyme neeuldehyde drogensse ‘ce. Tim edu SAT: Us tin ya chon dung din thudced kbéng sah bing ding éog do: Darn bio a tan tr 20a ngs bgab, ahi 18 khiog Sinn €8 sy hip thu 8b] én het boi ti Bn b, Tube cd sink Kh dang i208 ud en age eat hp ha twomg ty tém tuyln nh mech ‘TRAMS \@ hn hgp v6iligu php xa thang dye khuyde ho vs Tink in ng. an env ith 30. Te Jynghdu Khang sinh-PAE (pos boi eee) ATC de ne i tong nd ish tro 1g PALE (Patani Lecoeyt Eahaseemert Efe eth amd 6 Khlng Sih ning age dng tv i ct thyc botrong cath vt eho 0 ché do vi Whuin cin tain td op Sezyne mitre Wi tng treme Lhe dng de be tng sind vk i lp Sie wih ng sinh & ning odie tthe hap ‘Gloss, rhat ida ado duct day 1a KHONG DUNG chioBPHOPD cin sng sinh sb ToMIC ela chiém 40.50% dbi viele Flan duge x tye guy co BA PR ida ie ching VK Gr) khing king si, “ie ln sng git] AUCMIC 2 30 king hrm iorequinolondige xem ld me PK/PD, nue tis a ct 290% thn cOngtrong i tr nhiém ulndo Sieptccoceus prewmaria ELVGLPNG vh cephalosporin, Te cla chide 40- Sov ong bch ea the 4: Veicnapenea dng idm Kubo va dit had tn dt th dah TOMIC ln lag 18 20% vi 0% Phin 08 dint cho lu 59 vi 60: g-nhip vign donhim ring ah gentamicin, tém apd TV “Tobe ot? gi Che 6 ib dng Si zeta thube, gig ban ul 5-10 perl i. cno eng tube Ot cay ong mau ay tebe i digg du thi A tho glan thud 441 age nbng 6 bn nk rong miu. sme vi Said. 187mg va dé 10 si Smeg vi lO gi 4. 200mg vas din 10 gid ‘F Bit those nly cb by trick 6 go Ey =4 ‘leu heyng mtu qua gaa 1 1200mUphok Tin eu 1 dyeg tan dh (iu ohm) cho idm traytn 08 {qt dug nbog 6 thube Bi hye trong b Whoingtrilige 2 Sog/mL LOuphat 203 12003 8 5655 Ex 1200 x8,3)/0693 ©. (120% 12 + 0,093 4. Kh 6 60g inh terme |g ERYONG DIY DUDE CAN THO. RO-MON DUGE LY: DUE TAM SANG | — | pbs2 ‘Cau 1, Chi tage ton tn tr ede nad thing thn tube trong the hah did to]? én tim te ng edp 3 ta, sand Abn ey 2 va 5404 etng min ep 1 (0) Neo tim tenga ep 1 ads, sad dn ep 2 vi aa ing mi lp 3 ©. Nén tim tir ngudin cp 2 nade, sa dé dénedp 3 vii | cui cing moi ci | | 4. Nén tm ef 3 ngudin eng hie Cu 2. Khi tra eta trong the thus ten website DRUGS.COM, thing tin bye c4 thé ten eu durg UD Mite 6 treme the: (1) Page logh mite chim cit trong te; (IND Ce ohé wrong tds (IV) Hu qua foram the? © Chi Aang (6/4, (1D, CIN vA UV) ding bd AV)ding GB. uy vs avy ding Cau 3. Cae ngudn thong tin thude tin ety ngwet Inte si e6 thé sie dyng trong ké dom: (1) MIMS; (11) VIDAL; (111) Tir huromg dln sir dyn. thude; (LV) Durge dién Vigt Nam? a Chi(D ding /(D),(N, (NI) vA AV) ding b (vi ca) ding @), va (tt) ding Ciiu 4. Thude di dirge ching minh giam che bién 8 do tim mach vA bao vé thin. a. Saxagliptin Metformin @ Empogiinogin ‘et Pioglitazon Chu S. Duge thus Quée gin Vigt Nam thude nguén ‘thong tin thuée fp? ‘a Cipt cap b Capit 4d. Cap IV Ciu 6. Théng tin thude cho bénh nhin khie voi cho nin vitn y & didm nto, CHQN CAU SAI? Nglin gon vi dom gids hon @© reer sin cow: eu tam kao hon , Sir dung that ngt dé higu hon DE TIE NOC KY HLNAM HER m1 70,16 TRAM T 4, Cung cdp thang tin vé tén thude va chi dinh JC LY LAM SANE a medi RAD Tt po han |mAve: 24 & Ci 7 Aeon ce mga Oh te chy 1 dyn OHi8U AE atte ec whe es ace § tN eH ‘hus nghm ny sing neh mbit ed shown eben Ty Su dling thuin cus ec ehuyin pads npn ce Nghién eta bon chain «4. Nghien eiru doan he Ci 8, DE tw vn sie dung tude nyu didu tr} nn thm dye np chp my? chp! Ocinn & Cép mt Cip lv, Cau 9, Ngo the dyn bug thi, Hydrochtorothiazid con e6 the dyng: @ are cox sia do giam ths canni qua dem gu (8) Ge ené ing hor men carbonic anhydrase kh dang ligu tnip «Git that kal qua dng hind Comach Chu 10. Loi ich eda Gee ché men chuyén trong di te tang huyét ip, NGOAT TRU: a Heep do gidn mach — @Tang kali maw b. itgay phan xa giaocdm Cau 11, Rosana jam dam niu, 8. Co thd gian bie thai ngin (.b. Chuyén hoa qua CYP3A4 €. Khong clin gism liéu khi suy thin néng © Gide >50% LOL-ckhi ding lidu >20mgingay Ciu 12, Phdi hop 2 thude (khoi du) dirge Khu céo ctia VSH (phan hoi ting huySt 4p Vigt nan 2018 Adi v6 Ling huy&t kp 45 11, NGOALTRU (4. Chen kénh cana’ va lo tig (hiazidey b, Ue ehé men chuyén va to du pidng Vhiazide Ue che men chuyén vi ehen thy thé angiotens d, Chen thy thé angiotensin va loi tiéy gidne Thiazide Scanned with CamScanner be: Cau 13. Statin €6 tie dng ghim LDI-e do: 4 Kich hoat mes Lipoprotein lipase b./ Gidim ting hop thy thé LDL-¢ Ting phong thick VLDL. tir gan @ Le ché ting top cholesterol igi gan Clu 14, Thude sit dung efp ciru ting huyét ap khan edp: (BFurosemide (itm tiah mach) b.Nicardipin (tiém tinh mach) «¢ Nitroglyeerin (igen tinh mgeh) @§oprepxt wngy (Caw 15. Statin ft gay tHe dyng khong mong mubn u co do urge chuyén hod qua CYP2C9: @ Roswvasiain cc Atorvetatin “b. Lovastatin Simvastatin Cau 16, Phdi hop thude giip ting tie dung he dp, te dyng khéng mong mun "phi chi: @ Veissrtan = amtodipin Perindopril ~ hydrochlorothiazide © Lisinopril ~ Spironolacton 4, Valsartan + metoprolol Clu 17. Thude nio gay tie dyng khing mong mudn "46 bing": 2. Atorvastatin c. Fenofibate , Gemfibrsil @ Acit ricoinie ‘Cau 18, TIM CAU SAI: Phéi hop khing sinh chi edn iniét: a. Nhim giém nguy co xudt hign cde chung vi khuin dé khéng thudc khi digu tr} kéo dai. b. Néu chimg minh c nhi&m dng thoi n vada nda ein phbi bop mdi db phd. . Nhim det ay higp Ive digt khuin khi gép vi khudn nang thud mann. \Han ché déc tinh cia khang sinh do rit nein thai pian diéu tr. Ciu 19. Ting huyée ép di kam ny thn ning néa phéi hyp te ché men chuyén v6i Igi tiéu no: loi vi TRAM2 MADE: 25 4 4 Hydochlorothiazide _¢. Indapamide Furosemide CAdSpirorotacten CAv 20. ir dyng Metronidazole cho nhitng nau dang ubng regu cé thé dua dén tinh trong adn mnifa, dau din, 66 mat, do eo ché: 8, Metronidazol te ché enzym aleol dehydrogenas 1, Rurqu iy itech enaym Cytochrome Pia «&- Rua gily eam sng en2ym Cytochrome Paso @"erorisro ie eh eazy actly dehydrogenase Cau 21, M91 khsing slob c6 hg shy trfeh gh gat 1) 18 0,8 66 nga Bs @ {ia git v4 0 chin trong chuyén nea sind ne 1a thude trong earth (20% hub bi gan chuyén a nay ts di \/ ma khéng dén durge noi tie dng, ¢. 20% thude s? divge do thai qua thin, 4, Thude 5806 che teinh ganna Cu 22. Trong nghign eit in vitro by ToMIC It chi s6 dy bao higu qui diéu tr cia khang sinh nhom: a. Aminoglycosid ‘@berstactan. b, Fluorequinolon ( } Tit cé nhom khéng sin! Cau 23. Tht cf ede you t6 sau dy dda Lam tin nnguy cer gy de tinh eta gentamicin, NGO TR (© ing cing ie vs Parosemia . Diu i bang gentamicin kéo dai @ Nang 46 day cia gentamicin < 2 g/ml 4. Chi dinh 6 ngudi trén 70 tudi Chu 24, Céich ding xird thube 4, Pha lodng bing nurde trade Ki ding bb. Kh6ng sir dyng cho bénh nin c6 ba td duong cc. Lie du trade khi dling ua va bding DE: 2 TRAM 3 Cau 25. Sir dyng Thiazide ch theo dai Ha dung huyét (ee canxi mia He kali miu Vong nati ma Cf 26, Dang db khang eos Acinetobacter chi edn shay chm vid Colistin drge gol ls @ xox (hing ring) b MDR (Da khéng thud) © POR(Khing win bo). d. Thi ea ding Chu 27, Co mt don thube bao gbm: Maalox vi Ciproftoxacin, Kh wbng ding thot hal thude trén 6 thé lam ghim hdp thu tetracyctin do: a. Tang pH ds diy lim tetracyclin gidm boa tan ‘Tao phute chit ndi chelat ben viene khdnge tan Lam chim car ché dy thude Khoi dy dy 4. Cam img enzyme chayén héa thud Ciu 28, C6 mpt don nude bao bm: “Aspirin — Giipicia”, khi ubng edn thor hai thude c6 thé fy tng nguy co he dirdmg huyét quit mire ta do: 2. Tao twong tie @ giai doan tha tre Too wong tc tuome rank gin ké wn protein Taye twomg, ©. Aspirin gay edn tri hip thu Glipizid 4 Aspirin de ché enzym chuyén hoa thuds eyt-P4S0 Clu 29. Rifampicin lam gidm the dyng eda thube gira thai dutmg ubng 1a do: 2. Ueché enzym chuyén hoa thude ‘cam img enzym chuyén hoa thude Tao tuome tic trong trank gin két trén protein huyét trong . Gay cn tri hp thu Cha 30, Thube aide tr] bfah trho ngeye dp day — hye quan nao sau day cin thon trong Kh ding cho bgnh nhiin suy tim sung huyét va suy thin? a, Sucralfat @Aiginae b, Domperidon 4. Nopeid Chu 31. Dé ting higu qua tr] lols dp dhy — 14 trang, nén ubng Esomeprazok: a. Nhai trude khi ubng. ». Udng ngay bira an «. Ubng m6! lin day nhit rude khi ng (sng vio hive 30 — 60 phi trusse khi An sins 254 ‘Chu 32, MOC phy nd 74 tu6) than daw hire ddiu swang, vit et wbog, kem theo co cimg co doi ot sing, duge chi dinn do mit a6 sarang, ket q ehisé Fe Mt 0.94 6 eb xwong dit. Két lug, xuomg ©. Gidm mét dd xuomy, (Linh uimg Long xuamg nang MOL ba cy 71 Ludi khéng hat thy ing Fugu, vA tép thé dye 30 phiit mbi 148) Vin, Ba ey ubng calcium 500 mp/ vitamin 1 401 AU ngiy 3 tin, Ba ey ex0 1.75 m ngng 72 Ke. © SOT AMD cia ba ey 1A 1.9 & xwomg dai vi — 6 et sbng. Phit bibu ndo saw diy ding? 4 BMD dinh thucimg o cot song i Moancnmena so0 bed @ 01mg scone sect sing 1. Lotng xuomp dag dinh ghia id xty wong (Cau 34. Diéu trj nao sau day thich hop nhat ¢! baeu nay? t.ho did ir hd, dp tye ear vd jamin D G scsesises 19s0¢:0hs ln c.-Miacalefe bom vao mii 1 xit mbi ngaiy 4, Estrogen lién hgp + medroxyprogesteron 0.625/5 mg méi ngity (Clu 35. Néu ba ey trén ed chi sh T BMD —1.6 uromg dit va 2.1 6 xwong séng, nhin djnb + sau diy ding? a. BMD binh thuing @ xvemg dat @ iar min 46 40mg 0 xen di © Loting xtrong o xuemg di 4 Lodng strong dude dinh neha Khi pay xwom xiy Clu 36, Ba ey trée ntn didu tr] bing cdch nd a. Alendronate @"p twe dang caterum va vitamin D Teriparatid 4. Miacaleie bom vito mai hin nd npng SoKg, ahép viga do nhiém tring Gr(-) ngng, duye echt djnh gentamicin, Wom wuyeo IV trong 1 gly vet nbng a trong 1g nube ge Buia biét cio Hu eh dnt ta bao nn bide Vad eit thade ta 0,201/K 8 (200 x 0,8) » 160 my/ke 200 x 8)~ 1600 perky, © (200 x8) ~ 1600 mp/Ky 4 (200 508) 160 pike Ci 38, Thube e6 tia Mt 2H; 6 pl sau khi tiem mgt du duy midi, ndng 49 thube en Iai trong, cer thé a 40 emi b 2 ym ©) em (Cu 39, Phat biéu nio dudi diy la SAL: Véi lite ban dw duye chi dinh li 2mp/Kg, Nguyén the sie dyng khiing sinh duye thé hig &: 4 Céc aminoside c6 phi tie dng ci yéu trén vi Khulin Gri-) Ciin luru § thud 66 déc tinh khéng hdi phuc 1rén tai va thin © Clin gid dinh ty ligu do day a khang sinh khoang tr hiéu hep. d Lidu chi dinh trén 4a dat duoc néng 46 dinh hr mong mudn Tie ctu 40 dén chu dd Mot thube duye ding bing durtmg durrng 1V inhanh v6 tity 100mg. Sy glim nbng ad thube trong huyét trong duge bitu difn qua phirong trinh dwéd day, vé“ C tinh bling gies Calte* Chiu 40, Dibn bikn dong hye cia thude ti: Dong hoe Michaelis Menten, © do60g hoe dt nyan-tuyén tinh € Déng hoe mbt ngéin-bio hia 4. Dong hye hangin Chu 41, The a thal trir eas a, Tren 90% trong. 1 pies be Wi%etrone 1 810, thube @ 20% trong | pis 4.7,1% trong | gi TRAM 4 nat dich v.46 nhay ‘cam cua vi Khuin tai dia phuong. by. Liga chon khing sinh c6 ph hep nit gn vei huh hit ete tae nhin gay bénh 16 wing lly miu bEnk phim d8 phn lp vi ‘hua sau kh digu i dé digu chinh phihop «Dieu t Ahi chua eb bang chime vé wi Khun do hg 66 dig kign madi cay i Khun Ciu 43. Chon ya tie ehé bets sav dy cho bah nha Ling huyét ap ¢6 nhip tim aban vi suy thin: 4. Atenolol Metoproto! bb Acebutolol d Sotalol (Ciu 44, Dje tinh chon toe ed mit khiing sinh Ha qui trioh: 4 Tae nhin piy bénh wie dng Wen thude Thude tae dng én tae nh. ply ben © Co thé tae dng én thude 4. Thude the dng trén co thé Cau 45, Vign kim iy gi rio sau diy do tgo phir a. Lincomyein Ciprofloxacin ‘Cin 46, Sucratfat tam Kkhé Kehie khi ude dng tha a JFapphite chit khd tan 1 Lam thay di pI da cy Anh hung nh ing da diy ~ rude hp thy cia thude hen ving? Amoxiclin 4 Metronidazcle ip thu ci thud Cn tr 0 ig ‘Chu 47, Sy ie ehé ph trib vi Khu ko di sau ki ip aie vi Kg sinh ge got Mi: Sv higp bag bo ne (@ can sau khang inh (PAE) Diet khvén phy thupe thir gian 1 Digt Khun phu thude ndng dO. ‘Cw 48, Cite chi sb PRIPD trong sirdyng khan, sinh, NGOAI TRE a. PMIC @incane bb Cpeak/MIC . AUCooaMIC. DEs2 TRAM 5 49. Ngubn thong tin thube thud e6 tinh tin ey exo nbkt: (1) Chp 15 an) Cip 2; aH) chp 2 & Chi() ding, @caicry ding . Chi lit) ding 4.0, (1) vi (at) dong Cf $0. Pht hop thude nio sau diy khdng hyp 1 4. Metformin + Glyburid >. Dulaghtid + Empaglitogin ¢. Glimepirid + Linagliptin Cfiu $1. Bgoh ahin 44% thio during type 2 6 thé trang bée phi, nén cin ahic ira chpn thuée nto sau diy 4. Linagliptin © Alibiglutid . Dapagliftogin @ sulin NPH (Cau 52. Insulin nhanh diing dé kiém soa duirng. ryt sau an 06 je diém ©C¥ aint we ng sem va ic dune ngin b. Khdng c6 dinh va tée dung kéo dai © Hip thu vio méu nhanh, khéng e6 dinh The dung nga vi khing 66 dinh (Ciw 83, Trong Khuyén cho ve Chin doan va Didu ‘ej Tang huy&t 4p nam 2018 cia Hi Tim Mach hye Quée gia Vigt Nam, mite ching cir A cho biét ir ligu 66 tir? @ Niu nghien cite tam sing ngdu nhién hod phan tich gp . MBt nghién edu lim sang ngdu ahién hode cic nnghién ci 1én khsing ng nhién ©. Cée nghién eéru nho, ede nghién céru hdi tru 4. Su ddng thud cde chuyén gia (Céw 54 Thuée wu tin Iya chon phdi hop cho bénh nnhin dai thao dung type 2 ¢6 bénh tim mgeh do xovia 2. lnsulin ispro ‘e, Saxagliptin (DPP-4i) ‘Semaglutid (GLPI-RA)—d.Glyburid (SU) fu SS. Béah nhin dai thao duimg type 2, chi phi 12 vdn a? 6m 64 bgnh ahin, thube nio sau diy khong nén chon | uk ot & Glitand (sty Larglutid (LPL RAY « Pioghitazon (1719) @ tisutin sens Cha 86, Thube dit tr) 4 thio auirny the yng bio vf thhe nburng ph chm ahibe ding | 6 Ige edu thn cho phip. 2 Insslin regular by Metformin (Biganid) inagptin (DFP) @ Canapinogs (sei. 1-24) Cau $7. CHON CAL DUNG 4D chinh lgu insulin, ud xét wehigen dtm huyét2 kin Trinh kiém soat duimg huyét chde w hénh ahd i thio during gid 06 nhidu bike ching «Binh nhin dai théo dui dung huyét cha ¢ mnge tiga digo, mdi nam act nghiém HbA le | d. Khdng nén tiém insulin nén che lin tiém tree ni iu $8. Phbi hyp 2 thube nay sé ting mpuy cor ic a Dexamethason + Ibuprofen @Prednison + terbutain © Hydroconisol » Laratadin 4 ‘Tnamcinolon + Amoxil Cau 59, Ph6i hyp 2 thude nay s& ting nguy ea 9 diy a Dexamethason + Cefuroxim » Prednison + Salbutama ©. Hydroconisol + Fexofenadin @®Tiameinoton + indomethacin Cau 60, CHON CAU DUNG 4. Prednisolon phai wéng true khi in b. Hydroconison liéu ve ché min dich 20me/nga @ Hysrocortison diéu wi suy v6 thoome thés ip 4. Dexamethason luén pha: véng vio budt sing nurses UU Can tm | wo MONDLOCLY: DYE ASG eee DEz Cle 1.8 mt don habe bao gbm: Ciprofexacia vi Diosmectc (Smects), AM abng ‘ng thbttam kno Adp emu Clprefforacn dor “Teo phic ehle ho tan inte co bee Lin thay pd ty ‘Caen rg enzyme chuyén hou thabe Cyt PASO ‘Cle 2.4 me dom thube bao gbm: Ciprofloxacin va Vidn ktm, ki lag dbng thet ety plim hdp ‘ie Ciprofexacin th do: Teo phic cht kbs tan b Cintdcoboe ©. Canh tanh pi kd ra protein buy room 4 Anh hutagnbs ding da diy ~ ro (Clu 3.Statin 6 te dag ghim LDL-C do: 4 Kich hoot men Lipoprotein lipase >. Gidm dag hop thy thé LDL-C €. Ting phing thich VLDL gan @ Ue chk ne hep croteteot wigan vd tog ting hap sSluone tha thé LDL-C (Cha 4. t4t om habe phn c6: Omeprazole vi Clopidogrel, khtudng ang thitndy eu tress the MW elim tde dyng chdog kdttpp tidu elu eda ‘Clopldoere. do Omeprasse: 4 Lamting pt ds diy Ting di thi Clopdogrelqus dng thin @ cn enzyme cvPrcis Chm img enzyme CYP2CI9 (C40, Sucratfat tim kbs Mp thu ede hube unde Nit ubog én eth 4. Tap phe chit thé tan @ cin ro cove ¢ Lam thay di pit ds diy <4 Anh ing hu dag da dy - rust Ci 6. Ubag Omeprazole tia ngiy trong ila tf ‘vidi de dy ~td tring o6 nguy co ply thide Mtamin nbo sau iy? Vearin BI ‘Vitamin BS Ovinme 8 4 Vitarsin D Oco (DE THIHOC KY I NAMHOC 20202001; Uae ‘Mise thi DUOC LY LAM SANG | Diana dete YEA Thiigietphinwgm TRAM + MADE: 232 Chu 7.6 mt dom thube b Gtipizid”, Kh ulng ddag tho Gurbog buy qui mite ik das & Gly te ché enzyme chuyén bia thule 66 gan (Cytochrome Pay) Tyo ong te treme tranh pn ket trén protern yt trong © Trotaong the tzong tranh pls kee trén mo 4. Aspirin gly céntrd hip thu Glipizid ‘Cu & Simvastatin két hop vet ezetimibe nhdim: 4 Trinh tuomg ti thube qua CYP3A4 i the ding gid LDL-C ©. Guim de tinh ten thin 4. Ting tng bop thy thé LDL-C ‘Cin 9.Co cht tie dyng cis Domperidon trong (iu tr] Dinh trho nguye dy diy - thye quia Hi: & Liming trrong Wve co ving thye quin didi . The dy co cht Lim tring da diy -. Bang vét ltt thive qui, va dung (C4a 10. Thuée itu tr] bfnh trio nguye dg day — ‘thye quan mao sau Gly cin thin trong khi ding 4. opr (Cn 11, DE ting higu qua cidutrjbfah trio ‘gwys de dy thye quin, ubng Esomeprazole vio Saitek ung 5. Udngngay boa an 6. Ubog mf ln day ae re Ki ng (@ sg vo ic 30 ~60 pi rte Hh ng Cte 12. cha phil din ofan nbd die glkA st ing Sarat a atu ata tke ngeye dy day thye quin? 4 Ubog ls ng no (wong tog ngy sou boa in) Niairbin ving Oia siispiecmy 4 Udg mbt ln te Rn ps DE:2 TRAM2 GiB. Rese ah te trong quy tinh hog ddng cis BE théng Cin glde duye tal Vift Na 2 Dank gin eag nA uye tt VI Nam Tuyen truydn ed sai pnam Ra quyét dink can thin 80 oho Cau 14 Bade cult cangtrongquy teah hont Aton cin bf thing Can gid dre ta Vgt Nam Dinh gi nguy co @ trytnthong . Ra quyét dinh can thigp 4. Bloke (CA 18. Mot ba cy 71 tuél khong iit thubesft kh ubng range, va tip thé dye 30 phit mBi tun 3 thn Ba cy wéng calcium 500 mg/ vitamin ‘D400 TU ngiy 3 Min. Ba cy 20 1.75 mi nding 72 Kg. Chi sb ‘T-score cia ba ey lh—1.9 6 swomg dil vi T-score ~ 2.64 cbt séng. Phat biéu nio sau diy ang? a. Mit 6 song binh thyéng & cbt sing. b. Khdi lyon xuong tip @ eét sing @iroing xvore d 61 sing 4. Loiing xvomg duge dinh nghia khi 43 xiy ra gby wong (Ci 16. Diku tr] nao sau day thich hyp nbdt cho bi epaly? 1, Khong cl didw er thé. Tidp tye vbng catium vavitunin D @Atenaronat 70 mg véng mi tuba 1 tin ¢. Calcitonin 200 UI bom vao mii | xit mdi ng’y 4d, Teriparatid 20 meg tiém du6i da mdi ngay Chu 17. Néa ba cy tréneé chi s6 T-score lh -1.9 ‘& xurong Gal va T-score la -2.1 6 wrong sng, nhjn djnh mio sau diy ding? 2. Mit 6 xuomg binh thuimg 8 xuomg At @ Knbi tog xv09g hip d xvong di «. Lolagnumgé mong ii 4. Loang xuong duye inh nghts Ki ghy suong 43 xiyra ‘ cae 18, BA cp trong chu TZnée aida] bing rich nio? septpe ding calcium va vitamin D OLE Ear 70mg wos msi rein Lin Ser ay a wiof 79] €-Calctninbom vio m0200 Ul mii ely 4 Terpaatid 20:meg ism dui da mi rgiy (Chu 19. Chum gite duge nhim: '® Phit hin bidn 66 bt toi xdy ding thude. '. Dinh git mb tien quan pita bin eb bit let vi thebe dupe ding Jc. Phong tranh bin of bai it kh ‘di str dung thube Weiccis tin ding (Clu 20. Nguytn nbn nto sav. Gay €6 the gy ra ‘ido of bie igs Wen quan Gén vige ding thube: 4 Phin Gogo ha cha nae Sai sé edangedi dda ty Km tuln tn id rj eu Bah thn @ céccte ren ding ‘to 21. Pha on pn eg ea habe bo ebm: ‘8. Théi gian khoi phir va tin suit xudthign . Mite dtr wong v8 bu hia i sag ©. Tinh chit dage 1g ca thube (© cic ctu ven ging Cu 22: Nguin thong tn thute thuénge tinh ‘Ap nngtehgm at () Chip 1; () Cdp 25 (119) chat 4. Chi (1) dang Chi (tN ing ¢. (D va (Ill) ding 4. (D, CD) va (1) ding (Civ 23. Binh nhin si dyng Metformin vélida ¢61 én 3 thing vin chva dgt mye tu HbAe theo hung cd thé héa, néu chon phd hop thube thi 2 ThAnsulin hay chen loa! insulin thich hop a Tasulialispro Insulin regular Qlesutin g: argin Incline Cau 24. Thube itu tr] 441 tho tng type? wu ttn cho bfah suy tim va bénh thfn men, a, Sitagliptin 1b. Metformin . Pioglitazon @ Enpxzitogin ng gus inh DE:2 TRAM3 (Cau 25 Rifampetn to phim te dng edn thud ‘gen thal ing ung do: a. Ue cht enzym chayén héa thude (@ ie ing enzym euyEn athe ©. Teo turong tie tung tranh pin két trtn protein hy trong 4. Giycin trp ts (Chu 26 TIM CAU SA: Nedy may, sfety ph hep King sah Khéng due khuyén keh da: 4. Cit homed Khing sith phon king ed ng cd le tinh dupe dng hoe phi op. ©6508 ep wong st ego cho ‘hing sah cing mt ung ren «. Khdng phai ty If phdi hop nao cing cho the dung, higp dng tht, 4 Di cd mhidu dang ché phim phdihopebsin (Ciu27, Chon phit btu aing vt Eztimibe: 8 Phdi hop v6i statin efy men transaminase Ting vinchayén npc colesterl v gan jim hip thu cholesterol qua nigm mpc rugt (ti mit vi tir nguda ngogi sinh) 44 Ting qudtith oh eng hpi rt (Ci 28. Thode the dng kichthich Lipoprotein pat, ting Wek thude LDL-C nh dim de: ‘Atorvastatin Fevofbate Rein Aad ote Cin 29, Thode tpo phe vad mfte hese Mecfornin (Ci 44: Che ngudn thong tn thu tn ety nguit Fay ght sie dng trong ké don: () MIMS;

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