Institute of Chemistry

College of Science
University of the Philippines, Diliman, Quezon City

COURSE SYLLABUS
CHEM 26 INTRODUCTION TO QUANTITATIVE CHEMICAL ANALYSIS

A. Course Catalogue Description

1. Course Number Chem 26

2. Course Title Introduction to Quantitative Chemical Analysis

3. Course Description Principles and techniques of analysis with emphasis on volumetric

methods and stoichiometry; survey on common instrumental
methods

4. Prerequisite Chem 16 and Chem 16.1

5. Semester Offered Midyear Term 2023-2024

6. Course Credit 3.0 u

7. Number of Class Hours 48 hours

8. Meeting Type Blended (face-to-face and online)

9. Course Goal To develop sufficient understanding of the key concepts and skills
to solve quantitative chemical analysis problems.

B. Course Content

No. of
Course Topics Class Learning Objectives
Hours

I. Review 2.0

□ To explain heat effects and heat

a. Solution Thermodynamics changes in chemical reactions
occurring in solution phase.

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 □ To calculate heat changes in
common solution processes.

□ Compute concentrations of
substances in various ways and
b. Concentration Expressions units.
□ Apply the concept of dilution in
solutions.

II. Chemical Kinetics 4.5

□ Explain the concept of chemical

a. Factors affecting the rate of chemical reaction
kinetics and reaction rate.

b. Reaction Rate and Rate Law □ Explain the effect on

1. Rates of Reaction concentration of reactants based
2. Rate and Concentration on the order of reaction.
3. Rate and Stoichiometry □ Apply the different methods in
4. Rate Measurements determining the reaction orders
5. Rate Law and Reaction Order and rate law.

c. Rate Theories
□ Explain the theories of chemical
1. Collision Theory
kinetics.
2. Transition State Theory

□ Assess the effect of temperature

d. Temperature and Rate: Arrhenius Equation
on reaction rate.

e. Catalysis
□ Differentiate homogeneous and
1. Homogeneous Catalysis
heterogeneous catalysis.
2. Heterogeneous Catalysis

III. Dynamic Chemical Equilibrium 3.0

□ Explain the principles of

a. Concept of Equilibrium
chemical equilibrium.

b. Equilibrium Constant Expression, Keq

□ Derive Keq in terms of Kc, and
1. Concentration, Kc
Kp.
2. Pressure, Kp
□ Evaluate the extent of a reaction
3. Magnitude of Keq
based on the magnitude of Keq
4. Reaction Quotient, Q
and Q.
5. Heterogeneous Equilibria

□ Apply the concept of Le

Chatelier’s Principle in
c. Le Châtelier’s Principle
equilibrium systems.
1. Concentration, Pressure & Volume,
□ Determine the effect of changes
Temperature Changes
in the equilibrium system.
2. Catalyst Effect
□ Determine the effect of a
catalyst to the equilibrium

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 system.

IV. Acid-Base Equilibrium 4.5

a. Acids and Bases

1. Arrhenius Theory
□ Explain and differentiate the 3
2. Brønsted-Lowry Theory
theories of Acids and Bases.
i. Hydronium Ion
□ Apply Brønsted-Lowry Theory
ii. Proton-transfer Reactions
to Acid-base Equilibria.
iii. Conjugate Acid-Base Pairs
3. Lewis Theory

b. Acid-Base Behavior
1. Strengths of Conjugate Acid-Base
□ Evaluate strengths of conjugate
Pairs
acid-base pairs based on
2. Molecular Structure and Strength
molecular structure and Ka and
i. Binary Acids
Kb.
ii. Oxoacids
iii. Carboxylic Acids

c. Autoionization of Water: Ion Product of □ Explain relationship of Kw, pH

Water and pH and H3O+ concentration.

d. Acid-Base Systems
1. Strong Acids and Bases
2. Weak Acids
□ Calculate pH of acids and bases
3. Polyprotic Acids
given Ka and Kb, and vice versa.
4. Weak Bases
□ Apply ICE method to calculate
5. Ka and Kb Relationship
equilibrium concentrations.
6. Acid-Base Properties of Salt
□ Determine acid-base properties
Solutions
of salt solutions.
i. Monofunctional Acids and
Bases
ii. H3PO4, H2SO4, H2CO3

□ Explain how a buffer system

works.
e. Buffers
□ Calculate components of buffer
1. Composition and Action
system using
2. Buffer Capacity
Henderson-Hasselback
equation.

Long Exam 1 2.0

V. Solubility Equilibria 3.0

□ Determine the solubility

a. Solubility Product Constant, Ksp, and
product expression for partially
Solubility
soluble salts.

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b. Factors Affecting Solubility
1. Common-Ion Effect
□ Predict the effect of factors that
2. pH
affect the solubility equilibrium
3. Formation of complex ions and the
of substances.
concept of Kf
4. Amphoterism

□ Solve problems on selective

c. Precipitation and Separation of Ions
precipitation

VI. Introduction to Coordination

2.0
Compounds

□ Explain the formation of

coordination compounds using
Lewis acid-base theory.
a. Structure of Complexes □ Solve the effective charge of
1. Charges, Coordination Numbers complex given the charges of
2. Chelates metal and ligand and vice versa.
□ Classify ligands based on the
number of ligand’s binding sites
for complex formation.

□ Determine the name of the

coordination compound given
b. Nomenclature
its chemical formula, and vice
versa, using IUPAC.

VII. Electrochemistry 3.5

a. Electrochemical Cells
□ Differentiate galvanic and
1. Galvanic cell
electrolytic cells.
2. Electrolytic cell

b. Cell Potentials □ Assess the reactivity of

1. Standard Reduction Potentials oxidants/reductants based on
2. Oxidizing and Reducing Agents standard reduction potential.

□ Assess the spontaneity of

c. Spontaneity of Redox Reactions
processes based on cell
1. Free Energy Change
potential.

d. Cell EMF and Concentration

1. Nernst Equation □ Calculate the cell potential
2. Concentration Cells through the Nernst Equation.
3. Equilibrium Constants

□ Determine the amount of

e. Electrolysis
species reduced or oxidized
1. Molten Salts and Aqueous Solutions
after passage of current through
2. Faraday’s Law
Faraday’s Law.

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Long Exam 2 2.0

VIII. Introduction and Gravimetry 1.5

□ Explain the theoretical basis of

gravimetric analysis.
□ Make use of gravimetric factor
a. Stoichiometry in gravimetric calculations.
1. Calculations in Gravimetric Analysis □ Determine moisture content in
2. Calculations in Volumetric Analysis samples to calculate analyte
i. calculations with mmoles concentration in dry or as
received basis.
□ Perform calculations involving
millimoles.

IX. Volumetric Analysis 4.5

a. Introduction
1. Equivalence Point and End Point
□ Explain principles behind
2. Primary Standards
titrimetric analysis.
3. Standard Solutions
4. Titration Curves

□ Make use of titration data to

calculate concentrations and
determine the species involved
at various points during titration
(initial, pre- equivalence,
equivalence and post
b. Acid-Base Titration equivalence points).
1. Acid-Base Indicators □ Calculate pH as a function of
2. Titration Curves added titrant.
i. Strong Acids and Strong □ Evaluate the feasibility of
Bases titration based on Ka and Kb.
ii. Weak Acids and Weak □ Construct a pH titration curve.
Bases □ Identify the factors that affect
o Concentration Effects the shape of a pH titration
o Completeness of curve.
Reaction Effects □ Distinguish the titration curve
o Feasibility of Titration for a monoprotic and polyprotic
3. Applications and calculations acids and its equivalent bases.
□ Distinguish the various forms of
titrations curves for polyprotic
systems.
□ Perform calculations to
determine amount of analyte
from titration data.

c. General Principles of Redox Titrations □ Explain the principle of redox

1. Determining equivalence point titrations.
2. Applications and example □ Perform calculations to
calculations determine amount of analyte

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 from titration data.

X. Introduction to Potentiometry 2.5

□ Explain the principle behind

a. General Principles
potentiometry.

b. Reference Electrodes
□ Explain the function of
1. Calomel Electrode
reference electrode.
2. Silver/Silver Chloride Electrode

□ Explain the function of

Indicator electrode.
c. Indicator Electrodes
□ Distinguish the different types
1. Metallic Electrodes
of indicator electrodes and their
2. Membrane Electrodes
applications.
i. pH glass electrode
□ Learn the construction,
functions and applications of
the pH glass electrode.

XI. Introduction to Absorption Spectroscopy 2.0

□ Discuss the theory behind

a. Interaction of Radiation and Matter
molecular absorption
1. Electromagnetic Spectrum
spectrophotometry.
2. Spectroscopic Measurements

b. Radiation Absorption
1. Absorption Process □ Apply Beer’s law in
2. Spectra quantitative analysis.
i. Qualitative Information: λmax □ Discuss the limitations of
ii. Quantitative Information: Beer’s law.
absorbance
o Beer’s Law
o Beer’s Law Deviations

c. Instrumentation
1. Basic Components
2. UV-Vis Instruments □ Distinguish components of a
i. Single Beam UV-Vis spectrophotometer.
ii. Double Beam
iii. Multichannel Instruments

XII. Introduction to Separation Techniques 2.5

□ Explain the basic principles of

solvent extraction of analytes
a. Separation by Extraction
from simple matrices.
1. Principles
□ Perform calculations to
2. Distribution Coefficient
determine amount of analyte
from solvent extraction data.

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 □ Explain the basic principles in
b. Chromatographic Separation chromatography as described in
1. General Description and the simple column
Classification chromatography.
2. Elution and Column □ Know the standard
Chromatography chromatographic techniques and
3. Chromatograms the common stationary and
i. Qualitative Information: mobile phases.
Retention Time □ Make use of chromatographic
ii. Quantitative Information: data and information in the
Peak Area or Peak Height identification and quantitation
of analytes in a mixture.

Long Exam 3 2.0

Final Exam 2.0

C. Course Requirements and Assessment

Assessment Points Type of Assessmnet

Lecturer’s choice
Low Stakes Assessment 150 points Can be short quiz, assigned tasks
/problem sets, others

Not Departmental
Long Examination 1 100 points
Multiple Choice Questions and
(Topics 1 to 4)
Problem Solving

Not Departmental
Long Examination 2
100 points Multiple Choice Questions and
(Topics 5 to 7)
Problem Solving

Not Departmental
Long Examination 3 100 points
Multiple Choice Questions and
(Topics 8 to 12)
Problem Solving

Departmental
Final Examination 200 points
Multiple Choice

Pre-final grade of ≥
Exemption Grade
65% (≥ 292.5)

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 Passing 55%

D. Grade Equivalent

Class standing UP Grade Equivalent

95-100 1.00

90-94 1.25

85-89 1.50

80-84 1.75

75-79 2.00

70-74 2.25

65-69 2.50

60-64 2.75

55-59 3.00

49-54 4.0

≤48 5.0

E. Class Policies

1. Dropping Consent

Consent for dropping may be witheld if the student's standing is passing. If dropping for health reasons,
kindly ask your physician to make an explicit recommendation for you to drop the course in your
medical certificate.

2. Long Examinations

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 a) Examinations will be administered on-site. Each Long Exam will be divided into 2 parts, Multiple
Choice and Problem Solving.
b) Missed Examinations and Other Requirements:
i) There are no make-up exercises for missed quizzes, homework, or problem sets. A zero grade
will be given whether the reason is excused or unexcused.
ii) If the student misses one long examination:
(1) The student should present a proof of the relevant excuse for the absence—a medical
certificate issued by UP Health Service, force of nature, official university activity or
other reasons that the Chem 26 committee deemed acceptable—no later than the 2nd
class session following his/her return. A zero grade will be automatically given to the
student in the absence of such proof.
(2) The student will not be exempted from the Final examination.
(a) The Final Examination score scaled to 100 will be used for the missed exam if
the student prefinal grade standing is equal or above 65%. The Final
Examination score will be scaled to 300 if the student prefinal grade standing is
below 65%. This score will be used for Finals and missed exam.
(b) If the student misses more than one long examination even with a reasonable
excuse, a grade of zero will be given to the second missed long examination.
c) A student who misses the Final Examination shall be given a grade of INC if his pre-final grade
standing is passing (55%), otherwise the student will be given a grade of 5. For completion of INC,
the student has the option to take the completion exam during the schedule for removal examination
given within the semester or take the completion exam during the schedule for removal examination
within the semester or take the Final Examination in the following semesters within one academic
year.

3. Student Participation

To ensure productive learning of students, participation of student will be monitored via output from
formative assessments per module. Instructors will contact students who have missed assignments/activity
to check their reason of non-submission and aid as needed.

4. Attendance policy

University rule on attendance, no more than 20% of the total class hours may be missed. In a regular
semester, this is equivalent to exceeding 6 absences. Beyond this, a grade of 5.0 shall be given to the
student.

5. Photos and Videos

Taking photos or videos of lecture material and the instructor, especially during face-to-face classes, is
prohibited.

6. Cheating and Plagiarism

Any student found to violate University rules on intellectual dishonesty shall be subject to the
investigation process as prescribed by existing University guidelines.

Intellectual dishonesty – any fraudulent act performed by a student to achieve academic advantage or gain
for oneself or others, including but not limited to:

a) Plagiarism, defined as “the appropriation of another person’s ideas, processes, results or

words without giving appropriate credit”;
b) Fabrication, defined as “making up data or results”; falsification, or “manipulating research
materials, equipment, or processes or changing or omitting data or results such that the

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 research is not accurately represented in the research record”; distortion and/or destruction of
data;
c) Copying or providing the means or accessing means to copy exam answers, homework,
projects, laboratory experiments, term papers, etc.; possession and/or use of cheat devices
during an examination; allowing another person to take an examination in one’s name, and/or
impersonating another student or allowing someone to impersonate oneself in an academic
activity; and manipulating a corrected exam paper;
d) Submission of the same work in two or more courses without the instructors’ consent; and
e) Other acts analogous to a, b, c, and/or d (2012 Student Handbook).

Acts of Misconduct and Corrective Measures are also contained in the Student Handbook.

F. References

1. Brown, T.L., LeMay, H.E., Bursten, B.E., Murphy, C.J., Woodward, P.M. and Stoltzfus, M.W. (2017).
Chemistry The Central Science 14th ed. UK: Pearson Education
2. Christian, G. D., Dasgupta, P.K. and Schug, K.A. (2013) Analytical Chemistry, 7th ed. Wiley Global
Education.
3. Harris, D.C., Lucy, C.A. (2015) Quantitative Chemical Analysis, 9th ed. New York: W. H. Freeman
and Company.
4. Petrucci R., Hering F., Madura J. and Bissonette C. (2017). General Chemistry: Principles and Modern
Applications, 11th ed. Boston, MA: Pearson Learning Solutions
5. Silberberg M.S. (2013). Principles of General Chemistry, 3rd ed. USA: McGraw-Hill Companies, Inc.
6. Skoog, D.A., West, D.M., Holler, F. J. and Crouch, S. R. (2021) Fundamentals of Analytical
Chemistry, 10th ed. Belmont, CA, USA: Brooks Cole Cengage Learning
7. Skoog, D.A., West, D.M., Holler, F. J., Crouch, S. R. and Chen, S.C. (2012) Introduction to Analytical
Chemistry, 8th ed. Singapore: Cengage Learning Aisa Pte. Ltd.
8. Zumdahl S. S., Zumdahl S. A. and De Coste, D. J. (2018). Chemistry, 10th ed. Boston MA, USA:
Cengage Learning.

G. SCHEDULE FOR MIDYEAR TERM

Course Topics Dates

Orientation July 02

Review July 02

Chemical Kinetics July 03-05

Dynamic Chemical Equilibrium July 08-09

Acid-Base Equilibrium July 10-12

Long Exam I July 15

Solubility Equilibrium July 16-17

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Introduction to Coordination
July 18
Compounds

Electrochemistry July 19, 22

Long Exam II July 23

Introduction and Gravimetry July 24

Volumetric Analysis July 23-25

Potentiometry July 26

Absorption Spectroscopy July 29

Separation Techniques July 30-31

Long Exam III August 2

Final Exam August 6/7

**NOTHING FOLLOWS**

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