Human Pedigree

Group members:
Alpha, Mahathir A.
_______________________________
Halid, Nurhaliza P.
_______________________________
_______________________________

A.
Problems
1. Given the following, describe the phenotypes (normal or albino)
Normal(Homozygous dominant)
▪ AA = __________
Normal(Heterozygous)

▪ Aa = __________
Albino (Homozygous recessive)

▪ aa = __________

2. Fill out the blanks on the pedigree below. Remember that gray squares indicate
that the person has two recessive alleles (aa) and is an albino aa x Aa = Aa, A,
aa

aa Aa

Aa aa
Aa

3. How many children does this family have?

-There are 3 children in this family.
4. What are the sexes of the children?
-They are all female.
5. Fill out the banks of the pedigree below (AA, Aa, aa)
 AA Aa

aa AA Aa

aa Aa aa Aa
aa
6. How many children does the original couple have?
-They have 3 children
7. How many grandchildren?
-They have 3 grandchildren
8. What are the sexes of the children?
-The original couple has 1 male and 1 female, and their grandchildren
comprises of 2 female and 1 male.
B.
Find out which family members (as many as you can; siblings, parents, grandparents,
aunts, uncles, cousins, great=grandparents, etc.) with listed traits. (Collective answer)
Traits Characteristics you mom dad Sibling Sibling Sibling G- G-dad
mom

Finger Having finger hair

Hair (between
knuckles) is
x x x x x x x x
dominant over
lacking finger hair.

Tongue Ability to roll

rolling your tongue into
a “u” shape is x x x x x x x x
dominant over
not being able to
roll your tongue

✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Earlobes Free earlobes
are dominant
over attached
earlobes

Shape of Widow’s peak is x x x x x x x x

hairline dominant over no
widow’s peak

✔ ✔ ✔
Dimple Dimples are x x x x x
dominant over no
dimples

✔ ✔ ✔ ✔ ✔ ✔
Roman A nose with a x x
nose bump is dominant
over a straight
nose

✔ ✔ ✔ ✔ ✔ ✔ ✔ ✔
Eye Brown eyes over
blue
color
C.
Trait: Falconi anemia
Forms of the traits:

● The Dominant form is normal bone marrow function- in other words, no anemia

● The recessive form is Falconi anemia. Individuals affected show slows growth, heart

defects, possible bone marrow failure and a high rate of leukemia.

A typical pedigree for a family that carries Falconi anemia. Note that carriers are not indicated
with half-colored shapes in this chart.

Lino Maria

Liza Tony Peter Ann Diane John

Ff

Cora
ff
 Belen Ronel Rose
Ff

Ron
F

QUESTIONS:

To answer questions number 1 -5, use the letter “f” to indicate the recessive Falconi
anemia allele, and the letter “F” for the normal allele.

ff genotype
1. What is Maria’s genotype? ___________________________________
2. What is Lino’s genotype? FF genotype
___________________________________
Ff genotype
3. What are Diane and John’s genotypes? ____________________________
Ff genotype
4. Most likely, Liza’s genotype is _______________________________________