Professional Documents
Culture Documents
Needstick Injuries and Exposures
Needstick Injuries and Exposures
Cover Story
Needlestick injuries in dentistry
Time to revisit
Anjali Ravi, BDS; Priyanka K. Shetty, BDS, MDS; Preetha Singh, BDS, PGDipPH;
Dipti Wakode, BDS, PGDipPH; Stephen F. Modica, MLS;
Priyanka Kodaganallur Pitchumani, BDS; Davis C. Thomas, BDS, DDS, MSD, MSc Med, MSc
ABSTRACT
Background. Blood-borne pathogens (BBPs) are infectious microorganisms that are found in
human blood and can cause diseases in humans. Health care workers such as physicians, surgeons,
nurses, dentists, dental students, dental assistants, laboratory technicians, personnel handling in-
fectious waste, and other health care employees are at increased risk of exposure to these pathogens.
Percutaneous injuries from needles or other sharp objects are the major sources of BBPs in the
workplace. Needlestick injuries (NSIs) have the most potential to transmit and have the easiest
mode of transmission of BBPs.
Types of Studies Reviewed. The authors searched electronic databases (PubMed, Web of
Science, Google Scholar, Scopus, Embase, MEDLINE-Ovid) for studies and articles focused on the
various aspects of NSIs, their possible causes, prevention, and management protocols.
Results. There is a lack of literature on the global prevalence of NSIs among dental practitioners and
underreporting of NSIs by clinicians. The authors also found that dental students and inexperienced
practitioners were the most vulnerable. They found apparent inconsistencies in guidelines and rec-
ommendations from various regulatory and statutory agencies in charge of limiting and managing NSIs.
Conclusion. The most significant occupational risks for health care workers globally are NSIs.
Dentists are recognized as one of the high-risk groups for exposure to NSIs. Although the reporting
rate was noticeably low, the frequency of NSIs among dental students was alarmingly high.
Practical Implications. Appropriate and succinct training of dental health care workers is crucial
for prevention and management of NSIs. It is recommended that dentists familiarize themselves
with recommendations from such agencies and organizations as the Center for Disease Control and
Prevention, Occupational Safety and Health Administration, and American Dental Association.
Key Words. CDC; OSHA; state dental board; ADA; needlestick injury; blood-borne pathogen.
JADA 2023:154(9):783-794
https://doi.org/10.1016/j.adaj.2023.06.004
H
ealth care workers (HCWs) in general, and dental health care workers (DHCWs) in
particular, are prone to experiencing needlestick injuries (NSIs), thereby increasing their
risk of exposure to more than 20 types of infections.1-4 Because specific data on
DHCWs are scant in the literature, for the purpose of our review they are included under
HCWs, unless otherwise specified. The incidence of NSIs among HCWs has been reported to
be 43% globally, which is a substantial percentage in terms of World Health Organization
(WHO) statistics.5 NSIs were brought to light in the early 1980s, after the discovery of the
HIV. Exposure to hepatitis B virus (HBV) and hepatitis C virus (HCV) via an NSI incident is
now more of a concern than exposure to HIV.1 Agencies such as the Centers for Disease
Control and Prevention (CDC), WHO, and Occupational Safety and Health Administration
(OSHA) have formulated guidelines to decrease the incidence of NSIs and protect HCWs.
Although these universal guidelines have reduced the risk of NSIs, these incidents still occur.1 Copyright ª 2023
American Dental
A 2020 investigation on the global prevalence of NSIs reported that dentists and nurses are Association. All rights
more likely than other HCWs to have an NSI.4 reserved.
METHODS
We searched electronic databases (PubMed, Web of Science, Google Scholar, Scopus, Embase,
MEDLINE-Ovid) for studies and articles focused on the various aspects of NSIs, their possible
causes, and prevention and management protocols. The time range was 40 years, from January 1980
through March 2023. The key words included in the search were but were not limited to needle,
needlestick, needlestick injury, dentist, dental practice, dentistry, public health dentistry, and
community dentistry. All articles selected were in the English language and with access to the full
article. All other articles were excluded.
DEFINITION
Various government agencies, such as the National Occupational Research Agenda and Great
Britain’s Health and Safety Executive, describe a sharps injury as a piercing or puncturing stab injury
resulting from medical instruments like a scalpel, needle, and other sharp objects. This percutaneous
injury in turn causes exposure to body fluids, especially blood.11,12 The CDC has estimated that, in a
hospital-based health care setting, more than 50% of these sharps injuries are caused by a
needlestick.11
NSIs are defined by the Canadian Centre for Occupational Health and Safety and the CDC
either as an injury from the piercing of needle equipment such as a hypodermic syringe or as an act
of puncturing intact skin, resulting in exposure to blood and body fluids.13-15
EPIDEMIOLOGY
Most of the literature on NSIs pertain to the medical field. The WHO estimates that 3 million of
the 35 million HCWs are exposed to NSIs annually.16 The probability of contracting infectious
diseases in the descending order of prevalence is HBV, HCV, and HIV after a single encounter with
virus-infected blood from an NSI.2,17,18 The occurrence of these infections after an NSI was esti-
mated to be higher in number in lower-income countries than in higher-income ones.2 NSIs are
more common in women than in men.5,19 It has been determined that factors such as less work
experience and being younger than 30 years are shown to be connected to HCWs’ being more
prone to NSIs.16 Lack of familiarity with the work environment, lack of training, and inadequate
risk awareness are a few possible explanations.16 The incorporation of NSI-prevention programs,
availability of training sessions and accurate information regarding the management of NSIs,
awareness programs for encouraging reporting of NSI cases in hospitals, classification of NSIs as a
ABBREVIATION KEY priority, and introduction of the use of new equipment to reduce NSIs are among the factors that
contribute to the lower prevalence of NSIs in higher-income countries.2,4
BBP: Blood-borne
pathogen. Frequent BBP exposure in dentistry is attributed to factors such as close proximity of patients,
CDC: Centers for Disease frequent patient movements, and constant use of various sharp instruments. This perpetual threat of
Control and exposure to contaminated needles imperils dentists to contracting blood-borne infections and
Prevention.
experiencing emotional trauma.20 A Washington state study found that dental professionals
DHCW: Dental health care
worker. accounted for approximately 20% of percutaneous injuries sustained by HCWs. In addition, local
HBV: Hepatitis B virus. anesthetic syringe use and inappropriate recapping technique were responsible for NSIs in dentists
HCV: Hepatitis C virus. and dental hygienists. The most prevalent tasks that resulted in percutaneous injuries among dental
HCW: Health care worker.
NSI: Needlestick injuries.
assistants were cleaning the equipment, changing the anesthetic carpule, and recapping.21 In a
OSHA: Occupational Safety survey conducted in Germany, approximately 60% of dentists had at least 1 NSI encounter in their
and Health professional lifetime. The NSI incidents recorded in this study represent both lack of safe working
Administration. environment and strenuous working practices.22 According to a survey of Malaysian health care
PEP: Postexposure
professionals, dental care employees had the second highest frequency of NSI exposures country-
prophylaxis.
WHO: World Health wide.23 A systematic review conducted among DHCWs in Pakistan reported that the frequency of
Organization. NSIs among DHCWs was found to be varied, ranging from approximately 30% through 70%.24
OTHER EXPOSURES
Hypodermic syringes are known to be the most prevalent cause of NSIs among HCWs.85 There is a
reported higher occurrence of NSIs among oral maxillofacial surgeons during intermaxillary fixation
procedures.92
PREVENTION
The WHO underlines the need for HCWs to have appropriate training to reduce the occurrence of
NSIs in a hospital context and the adoption of universal infection prevention measures.8 There is
an emphasis on following infection control standards and various prevention protocols in an
attempt to eliminate or minimize percutaneous exposure incidences.93-95 However, NSIs are a major
concern in the dental workplace, particularly among less experienced dentists and dental stu-
dents.16,27,93 The preventive measures as per recommendations from the various agencies are
summarized below.
Virus
Viral hemorrhagic fever viruses57,61
Dengue57,58
Hepatitis B9
Hepatitis C9
Hepatitis D57,62
Hepatitis G57,63
Herpes simplex 13,57,64,65
HIV1,66
Cytomegalovirus9
Epstein-Barr virus9
Kyasanur virus57,67
Varicella-zoster virus57,68
Bacteria
Corynebacterium diphteriae57,64
Leptospira icterohaemorrhagiae57,69
Mycobacterium leprae57,70
Mycobacterium tuberculosis57,64
Mycoplasma caviae71
Rickettsia rickettsii (Rocky Mountain spotted fever)57,72
Rickettsia typhi (typhus)57
Staphylococcus aureus57,73
Treponema pallidum9,57,64
Clostridium tetani1
Parasite
Leishmania species57,74
Plasmodium cynomolgi57,75
Plasmodium malariae3,57,76,77
Plasmodium vivax57,75
Plasmodium falciparum78
Trypanosoma brucei57,74
Yeast
Cryptococcus neoformans57,79
Sporotrichum schenkii57,80
OSHA
In the United States, OSHA decides the standards related to prevention and postexposure man-
agement of NSIs in employees.61,96 Percutaneous injuries accounted for most of the BBP trans-
mission in employees covered under OSHA. Thus in 2000, the OSHA BBP standard was revised to
include the Needlestick Safety and Prevention Act (HR 5178).61,97 A summary of the components
of the OSHA 2000 NSI prevention act is given in Figure 1. Although OSHA has mandated
abstinence from needle recapping, it has an apparent exemption for the special setting of dentistry.
The corresponding OSHA regulation published in 2001 indicates this exemption for dentistry and
recommends the use of a 1-handed technique or a mechanical device.98 One of the techniques
recommended for recapping needles in dentistry is shown in Figure 2.
Needlestick Safety
and Prevention Act
Occupational Safety and
Health Administration
2000
Figure 1. Main components of the Needlestick Injury Prevention Act by the Occupational Safety and Health
Administration.99
European Agency for Safety and Health at Work is given in Figure 3, and the hierarchy of controls
recommended by the same organization is given in Figure 4. The recommendations from various
regulatory agencies for prevention of NSIs for HCWs in general, and dentists in particular, are
summarized in Box 2.101-107
Consistent The
overall restriction
prevention against
policies Adequate recapping
training; use
of personal
protective
equipment;
providing
vaccination
Figure 3. Risk management measures recommended by the European Agency for Safety and Health at Work.101,102
Gloves
exposed area to express blood out. Application of harsh chemical agents including disinfectants at
the exposure site is not recommended.81 Prompt reporting to the appropriate chain of command of
any exposure to BBPs is crucial. A thorough examination of the exposure and exposure source is
required. The exposure routes and how the exposure occurred should be documented. Employees
must be evaluated medically as soon as possible owing to the imminent nature of succinct
chemoprophylaxis within a short time. Depending on the type and source of the exposure, follow-up
evaluations at an occupational clinic should take place at recommended regular intervals. Usually,
the interval sequence is 1 week, 12 weeks, 6 months, and 12 months. During these visits, the
HCW’s health is evaluated, and repeat testing may be required depending on the infection. Ac-
curate recording of the incident description and postexposure management should be part of the
employee’s confidential medical record.61 The following are the PEP measures for the 3 most
common infections contracted after an NSI.
HCV
The CDC has updated the recommendations for treating acute HCV infections. These recom-
mendations stipulate that baseline testing of the source patient and HCW should be performed
within 48 hours after exposure. There are 2 recommendations when testing the source patient.
The source patient can first be tested for HCV RNA using a nucleic acid test. This method is
favored, especially if the source patient has engaged in behaviors that raise the risk of contracting
HCV (such as using an injectable drug within the past 4 months) or if risk cannot be estimated
accurately. The second option is to first check the source patient for HCV antibodies and, if the
results are positive, to check for HCV RNA. A detailed procedural protocol with specifics can be
found in Moorman and colleagues.114
HBV
The risk of developing occupationally acquired HBV infection among HCWs remains high, owing
primarily to exposure to patients with chronic HBV infection. HBV vaccination is recommended
for at-risk HCWs. Postvaccination serologic testing is also highly recommended for the same group.
The importance of timely vaccinations and prompt postexposure protocols can be found in Schille
and colleagues.115
CLINICAL PEARLS
HCWs in general, and dentists in particular, are vulnerable to NSIs. Considering even higher
susceptibility of dental students, specifically in their third and final years, to NSIs, they may need
to be retrained in prevention, reporting, and management of NSIs. Emphasis should be given on
prevention using succinct education and training of the entire dental team. Prompt reporting is
crucial in an attempt to update the available statistics on NSIs. The dental team should be
educated and in compliance with immunization and prompt postexposure protocols. The dental
team should be well versed in proper instrument handling and sharps disposal protocols. The
dental team needs to understand the importance of avoiding prolonged and hectic procedures
toward the end of their daily work schedule, in an attempt to minimize NSIs secondary to fatigue.
The apparent incongruence of guidelines and recommendations may need to be addressed at the
level of the regulatory agencies. With a view that further pandemics such as COVID-19 are only
a question of when and not if, HCWs should be aware of and prepare for the high possibility of
NSIs during such events. HBV, HCV, and HIV reportedly carry a single exposure risk of 6%
through 30%, 0% through 7%, and 0.2% through 0.5%, respectively, when a person is exposed
to virus-infected blood.17
Dr. Ravi is a clinical preceptor, General Dentistry and Comprehensive Care, Dr. Kodaganallur Pitchumani is a postgraduate resident, Department of
Rutgers School of Dental Medicine, Newark, NJ. Periodontology, The Ohio State University College of Dentistry, Columbus,
Dr. Shetty is an assistant professor, Department of Oral Pathology and OH.
Microbiology, A. J. Institute of Dental Sciences, Mangalore, India. Dr. Thomas is an associate clinical professor, Center for
Dr. Singh is a clinical preceptor, General Dentistry and Comprehensive Temporomandibular Disorders and Orofacial Pain, Department of
Care, Rutgers School of Dental Medicine, Newark, NJ. Diagnostic Sciences, Rutgers School of Dental Medicine, Newark, NJ.
Dr. Wakode is a clinical preceptor, General Dentistry and Comprehensive Address correspondence to Dr. Thomas, Center for Temporomandibular
Care, Rutgers School of Dental Medicine, Newark, NJ. Disorders and Orofacial Pain, Department of Diagnostic Sciences, Rutgers
Mr. Modica is a librarian, Information and Education Services, George F. School of Dental Medicine, 110 Bergen St, Newark, NJ 07103, email
Smith Library of the Health Sciences, Rutgers Biomedical and Health davisct1@gmail.com.
Sciences, Newark, NJ. Disclosures. None of the authors reported any disclosures.
1. King KC, Strony R. Needlestick. StatPearls. Stat- 14. The National Surveillance System for Healthcare pathogens and management of exposure incidents in
Pearls Publishing; 2022. Workers (NaSH). U.S. Department of Health and Human Nigerian dental schools. J Dent Educ. 2007;71(6):832-837.
2. Mengistu DA, Tolera ST, Demmu YM. Worldwide Services, Centers for Disease Control and Prevention; 2007. 27. Huang J, Li N, Xu H, Liu Y, An N, Cai Z. Global
prevalence of occupational exposure to needle stick injury 15. Needlestick and Sharps Injuries. Canadian Centre for prevalence, risk factors, and reporting practice of needlestick
among healthcare workers: a systematic review and meta- Occupational Health and Safety; 2018. and sharps injuries among dental students: a systematic re-
analysis. Can J Infect Dis Med Microbiol. 2021;2021: 16. Hassanipour S, Sepandi M, Tavakkol R, et al. view and meta-analysis. J Hosp Infect. 2022;129:89-101.
9019534. Epidemiology and risk factors of needlestick injuries 28. Zachar JJ, Reher P. Percutaneous exposure injuries
3. Saadeh R, Khairallah K, Abozeid H, Al Rashdan R, among healthcare workers in Iran: a systematic reviews amongst dental staff and students at a university dental
Alfaqih M, Alkhatatbe O. Needle stick and sharp injuries and meta-analysis. Environ Health Prev Med. 2021;26(1): clinic in Australia: a 6-year retrospective study. Eur J Dent
among healthcare workers: a retrospective six-year study. 43. Educ. 2022;26(2):288-295.
Sultan Qaboos Univ Med J. 2020;20(1):e54-e62. 17. Xu X, Yin Y, Wang H, Wang F. Prevalence of 29. Shaghaghian S, Golkari A, Pardis S, Rezayi A.
4. Bouya S, Balouchi A, Rafiemanesh H, et al. Global needle-stick injury among nursing students: a systematic Occupational exposure of Shiraz dental students to patients’
prevalence and device related causes of needle stick in- review and meta-analysis. Front Public Health. 2022;10: blood and body fluid. J Dent (Shiraz). 2015;16(3):206-213.
juries among health care workers: a systematic review and 937887. 30. Pavithran VK, Murali R, Krishna M, Shamala A,
meta-analysis. Ann Glob Health. 2020;86(1):35. 18. Cheng HC, Su CY, Yen AM, Huang CF. Factors Yalamalli M, Kuma AV. Knowledge, attitude, and prac-
5. Hosseinipalangi Z, Golmohammadi Z, Ghashghaee A, affecting occupational exposure to needlestick and sharps tice of needle stick and sharps injuries among dental
et al. Global, regional and national incidence and causes of injuries among dentists in Taiwan: a nationwide survey. professionals of Bangalore, India. J Int Soc Prev Community
needlestick injuries: a systematic review and meta-analysis. PLoS One. 2012;7(4):e34911. Dent. 2015;5(5):406-412.
East Mediterr Health J. 2022;28(3):233-241. 19. Matsumoto H, Sunakawa M, Suda H, Izumi Y. 31. Smith WA, Al-Bayaty HF, Matthews RW. Percu-
6. Al-Zoughool M, Al-Shehri Z. Injury and infection Analysis of factors related to needle-stick and sharps in- taneous injuries of dental personnel at the University of
in dental clinics: risk factors and prevention. Toxicol Ind juries at a dental specialty university hospital and possible the West Indies, School of Dentistry. Int Dent J. 2006;
Health. 2018;34(9):609-619. prevention methods. J Oral Sci. 2019;61(1):164-170. 56(4):209-214.
7. Mahboobi N, Mahboobi N, Oliaei P, Alavian SM. 20. Huang J, Li N, Xu H, et al. Epidemiology of nee- 32. Stewardson DA, Burke FJ, Elkhazindar MM, et al.
Hepatitis C virus: its implication for endodontists. Iran dlestick injury exposures among dental students during The incidence of occupational exposures among students
Endod J. 2014;9(3):169-173. clinical training in a major teaching institution of China: in four UK dental schools. Int Dent J. 2004;54(1):26-32.
8. AlDakhil L, Yenugadhati N, Al-Seraihi O, Al- a cross-sectional study. J Dent Sci. 2022;17(1):507-513. 33. Stewardson DA, Palenik CJ, McHugh ES, Burke FJ.
Zoughool M. Prevalence and associated factors for nee- 21. Shah SM, Merchant AT, Dosman JA. Percuta- Occupational exposures occurring in students in a UK
dlestick and sharp injuries (NSIs) among dental assistants neous injuries among dental professionals in Washington dental school. Eur J Dent Educ. 2002;6(3):104-113.
in Jeddah, Saudi Arabia. Environ Health Prev Med. 2019; State. BMC Public Health. 2006;6:269. 34. Hbibi A, Kasouati J, Charof R, Chaouir S, El
24(1):60. 22. Wicker S, Rabenau HF. Occupational exposures to Harti K. Evaluation of the knowledge and attitudes of
9. Utkarsha L, Srinidhi D, Sudhakara Reddy K. bloodborne viruses among German dental professionals dental students toward occupational blood exposure ac-
Post exposure prophylaxis to occupational injuries for and students in a clinical setting. Int Arch Occup Environ cidents at the end of the dental training program. J Int Soc
general dentist. J Indian Prosthodont Soc. 2014;14(suppl Health. 2010;83(1):77-83. Prev Community Dent. 2018;8(1):77-86.
1):1-3. 23. Ishak AS, Haque MS, Sadhra SS. Needlestick in- 35. Halboub ES, Al-Maweri SA, Al-Jamaei AA,
10. Gaballah K, Warbuton D, Sihmbly K, Renton T. juries among Malaysian healthcare workers. Occup Med Tarakji B, Al-Soneidar WA. Knowledge, attitudes, and
Needle stick injuries among dental students: risk factors and (Lond). 2019;69(2):99-105. practice of infection control among dental students at
recommendations for prevention. Libyan J Med. 2012;7. 24. Pervaiz M, Gilbert R, Ali N. The prevalence and Sana’a University, Yemen. J Int Oral Health. 2015;7(5):15-
11. Stop Sticks Campaign. Centers for Disease Control underreporting of needlestick injuries among dental 19.
and Prevention. February 26, 2019. Accessed March 6, healthcare workers in Pakistan: a systematic review. Int J 36. Wu L, Yin YL, Song JL, Chen Y, Wu YF, Zhao L.
2023. https://www.cdc.gov/nora/councils/hcsa/stopsticks/ Dent. 2018;2018:9609038. Knowledge, attitudes and practices surrounding occupa-
sharpsinjuries.html 25. Pournaghi-Azar F, Mohseni M, Ghojazadeh M, tional blood-borne pathogen exposure amongst students
12. The Health and Safety (Sharp Instruments in Health- Derakhshani N, Azami-Aghdash S. Prevalence and causes in two Chinese dental schools. Eur J Dent Educ. 2016;
care) Regulations 2013: Guidance for Employers and of needlestick injuries among dental care providers: a 20(4):206-212.
Employees. Health and Safety Executive; 2013. systematic review and meta-analysis. Research Square. 37. Machado-Carvalhais HP, Martins TC, Ramos-
13. Wicker S, Cinatl J, Berger A, Doerr HW, Gott- November 8, 2019. Preprint, Version 1, active. https://doi. Jorge ML, Magela-Machado D, Paiva SM, Pordeus IA.
schalk R, Rabenau HF. Determination of risk of infection org/10.21203/rs.2.17028/v1 Management of occupational bloodborne exposure in a
with blood-borne pathogens following a needlestick injury 26. Sofola OO, Folayan MO, Denloye OO, dental teaching environment. J Dent Educ. 2007;71(10):
in hospital workers. Ann Occup Hyg. 2008;52(7):615-622. Okeigbemen SA. Occupational exposure to bloodborne 1348-1355.