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LAKSHYA (NEET)
BIOLOGY COMPREHENSIVE ASSIGNMENT DPP-11

1. An organism or cell having a chromosome (3) All the heterochromatin in female cells
number exactly multiple of haploid number (4) One of the two X–chromosomes in
is known as somatic cells of females.
(1) Aneuploid (2) Euploid 7. Mustard gas is a
(3) Hyperploid (4) Hypoploid (1) Primary air pollutant
2. Triticale, a new crop plant has been (2) A chemical mutagen
produced by a cross between (3) A poisonous gas
(1) Wheat and maize (4) All of the above
(2) Wheat and barley 8. Both sickle cell anaemia and Huntington’s
(3) Wheat and rye chorea are
(4)Wheat and sugarcane (1) Bacteria-related diseases
3. Pick out the correct statements (2) Congenital disorders
(i) Haemophilia is a sex- linked recessive (3) Pollutant-induced disorders
disease (4) Virus-related diseases
(ii) Cystic fibrosis is an autosomal dominant 9. Inversion without involving the centromere
gene disorder is called
(iii) Phenylketonuria is an autosomal (1) Paracentric
recessive gene disorder (2) Monosomy
(iv) Sickle cell anemia is an X–linked (3) Pericentric
recessive gene disorder
(4) Tautomerization
(1) (i) and (iii) are correct
10. Aneuploidy which results in loss of a
(2) (ii) and (iv) are correct complete homologous pair of chromosome is
(3) (i), (iii) and (iv) are correct (1) Trisomy (2) Tetrasomy
(4) (i), (ii) and (iii) are correct (3) Nullisomy (4) Euploidy
4. Which is a trisomic condition ? 11. Loss or gain of a segment of DNA results in
(1) 2n–1 (2) 2n + 1 (1) Frame - shift mutation
(3) 2n + 2 (4) 2n + 3 (2) Point mutation
5. Polyploidy means : (3) Polyploidy
(1) Occurrence of haploid set of (4) Chromosomal aberration
chromosomes
12. In which of the following disorder a single
(2) Occurrence of diploid set of protein that is a part of the cascade of
chromosomes proteins involved in blood clotting is affected
(3) Occurrence of more than diploid set of ?
chromosomes (1) Thalassemia
(4) None of the above (2) Sickle cell anaemia
6. Barr body in mammals represents (3) Haemophilia
(1) All the heterochromatin in male and (4) Phenylketonuria
female cells 13. Mark the correct statement (w.r.t. stickle cell
(2) The Y-chromosome in somatic cells of anaemia)
male
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(1) Homozygous individuals for HbS are recessive mutation. The first child of a couple
apparently unaffected with normal skin pigmentation was an
(2) Heterozygous individuals exhibit sickle albino. What is the probability that their
cell trait second child will also be an albino ?
(3) Heterozygous individuals are affected as (1) 50% (2) 75%
well as carrier (3) 100% (4) 25%
(4) Homozygous individuals for HbA show 20. A woman with two genes for haemophilia
the diseased phenotype and one gene for colour blindness on one of
14. The defect sickle–cell anaemia is caused by the ‘X’ chromosomes marries a normal man.
the of glutamic acid by valine at the 6th How will the progeny be ?
position of the globin chain of the (1) 50% haemophilic colour–blind sons and
haemoglobin molecule 50 haemophilic sons
(1) Substitution, b (2) Deletion, a (2) 50% haemophilic daughters and 50%
(3) Duplication, b (4)Translocation, a colour blind daughters
15. A normal woman, whose father had colour (3) All sons and daughters haemophilic and
blindness, married a normal man. What is colour–blind
the chance of occurence of colour blindness (4) Haemophilic and colour–blind daughters
in the progeny ? 21. The chromosome constitution 2n-2 of an
(1) 25% (2) 50% organism represents
(3) 100% (4) 75% (1) Monosomic (2) Nullisomic
16. In phenylketonuria (3) Haploid (4) Trisomic
(1) Break down of phenylalanine is rapid 22. A man whose father is a colourblind, marry a
(2) Accumulation of phenylalanine in body woman, who is a daughter of colourblind
(3) Chromosomal consitution of patient mother. The offspring of this couple will be
changes (1) All daughter and sons are colourblind
(4) TSD gene situated on chromosome 15 (2) 50% colourblind and 50% normal son
undergoes mutation (3) Carrier normal-daughter and colourblind
17. A species has 2n = 16 chromosomes. How sons
many chromosomes will be found per cell in (4) Colourblind sons and normal daughter
each of the following mutant species ? 23. Christmas disease is another name of
I. Monosomic II. Autotriploid (1) sleeping sickness
III. Trisomic (2) Down’s syndrome
IV. Double monosomic (3) hepatitis
V. Nullisomic (4) Haemophilia – B
The correct sequence of chromosomes for (I 24. The ‘Christmas disease’ patient lacks
to V) are antihaemophilic
(1) 15, 24, 17, 14, 14 (1) homogentisic acid oxidase
(2) 24, 32, 18, 40, 12 (2) factor VIII
(3) 16, 22, 14, 21, 16 (3) factor XI
(4) 26, 34, 20, 42, 14 (4) factor IX
18. Albinism is a congenital disorder resulting 25. An abnormality which is not due to recessive
from the lack of the enzyme gene is
(1) Tyrosinase (1) phenylketonuria (2) alkaptonuria
(2) Xanthine oxidase (3) polydactyly
(3) Catalase (4) Tay-Sach’s syndrome
(4) Fructokinase 26. Sickle cell anaemia
19. Albinism is known to be due to an autosomal

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(I) Follows the same inheritance pattern as Deficiency

that of hemophilia (3) Colour blindness
(II) Follows the same inheritance pattern as (4) Sickle- cell anaemia
that of albinism 34. Progressive degeneration of brain cells
(III) Is a sex–limited trait results from
(IV) Is due to a single recessive point (1) cystic fibrosis
mutation (2) Marfan syndrome
leading to the substitution of a single amino (3) thalassemia
acid in the b–chain of hemoglobin. (4) Huntington disease
The correct statements are 35. An inborn error of metabolism which
(1) All are correct eventually affects mental development is
(2) All except (I) are correct (1) albinism
(3) All except (III) are correct (2) phenylketonuria
(4) (II) and (IV) are correct (3) anaemia
27. Individuals with albinism lacks the dark (4) Bleeder’s disease
pigment in 36. I. Haemophilia II. Cystic fibrosis
(1) skin (2) hair III. Sickle-cell anaemia
(3) iris (4) All of these IV. Colour blindness
28. In phenylketonuria, the phenylalanine gets V. Cancer VI. Plague
converted to
VII. Phenylketonuria VIII. Thalassaemia
(1) acetic acid Choose the correct options for Mendelian
(2) phenyl acetic acid disorders :
(3) phenyl pyruvic acid (4) pyruvic acid (1) I, II, III, IV, VI, VIII
29. Haemophilia is due to mutation in (2) I, II, III, IV, VII, VIII
(1) X and Y - chromosomes (3) I, II, III, IV, V, VI
(2) Y-chromosomes (4) I, II, III, IV, V, VIII
(3) X-chromosomes 37. ‘Gigantism’ is mostly found in
(4) autosomal chromosome (1) Autopolyploids (2) Allopolyploids
30. Which of the folloiwng is not a hereditery (3) Haploids (4) None of these
disease ?
38. Which of the following are correct ?
(1) Cretinism (2) Haemophilia
I. An inversion is produced, when there
(3) Thalassemia (4) Cystic fibrosis are two breaks in a chromosomes and the
31. Polyploid derived from two different species intercalary segment reunites in reverse order
is called II. Reciprocal translocations involve mutual
(1) autopolyploid (2) triploid exchange of chromosome segments
(3) allopolyploid (4) monoploid between two pairs of non–homologous
32. A man who carries holandric gene in his Y- chromosomes
chromosome, marries a normal woman, the III. In paracentric inversion, inverted
said gene will transmitted to segment includes centromere
(1) all their sons IV. In pericentric inversion, inverted
(2) 50% of their sons segment does not included centromere
(3) all their daughters Codes
(4) 50% of their daughters (1) I and II (2) III and IV
33. Select the hereditary disease which is carried (3) II and III (4) Only IV
on autosomes ?
(1) Haemophilia (2) G–6–PD 39. Match the following Columns.

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Column I Column II A B C D
A. Non-disjunction 1. A segment of (1) 4 3 1 2
the sequence is (2) 4 3 2 1
turned over and (3) 1 2 3 4
reinserted (4) 2 3 1 4
B. Translocation 2. Exchange of 41. In b–thalassaemia, the affected chromosome
material between is
non- homologousc (a) 16th (b) 14th
hromosomes (c) 13th (d) 11th
C. Inversion 3. A portion of 42. Thalassaemia is
the message is (1) autosomal recessive disease
completely lost (2) autosomal dominant disease
D. Duplication 4. Certain (3) sex–linked dominant disease
sequences are (4) sex–linked recessive disease
copied more often 43. Polyploidy can be induced by the application
than other of
E. Deletion 5. Chromosomes (1) auxin (2) kinetin
fail to sort (3) colchicine (4) ethylene
properly during 44. Match the following columns.
meiosis Codes Column - I Column - II
A B C D E A. Sickle-cell anaemia 1. Sex - linked
(1) 5 2 1 4 3 B. Colour blindness 2. Autosomal
(2) 4 1 5 2 3 chromosome-7
(3) 3 2 1 4 5 C. Phenylketonuria 3. Autosomal
(4) 2 3 4 1 5 chromosome-11
40. Match the following Columns D. Cystic fibrosis 4. Autosomal
Column I Column II chromosome - 12
(Chromosome aberrations) (Consequences) Codes
A. Intercalary deletion 1. Transfer of A B C D
part of
chromosome (1) 3 4 1 2
to non–homologous (2) 4 1 2 3
chromosomes (3) 4 1 4 2
B. Duplication 2.Centromere is (4) 3 1 4 2
not involved
C. Paracentric inversion 3. Presence of 45. More men suffers from colour blindness
same genes in than women because
chromosome in (1) women are more resistant
more than two (2) male sex hormone testosterone causes
doses the disease
D. Translocation 4. Two breaks (3) the colourblind gene is carried by Y–
followed by chromosome
deletion and (4) men are hemizygous and one defective
reunion Codes gene is enough to make colourblind

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35. (4)
Answer key- 36. (2)
1 (2) 37. (1)
2. (3) 38. (1)
3. (1) 39. (1)
4. (2)
40. (2)
5. (3)
6. (4) 41. (4)
7. (4) 42. (1)
8. (2) 43. (3)
9. (1) 44. (4)
10. (3) 45. (4)
11. (4)
12. (3)
13. (2)
14. (1)
15. (1)
16. (2)
17. (1)
18. (1)
19. (4)
20. (1)
21. (2)
22. (1)
23. (4)
24. (4)
25. (3)
26. (4)
27. (4)
28. (3)
29. (3)
30. (1)
31. (3)
32. (1)
33. (4)
34. (4)

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