Lyceum of the Philippines University

College of Nursing

DRUG STUDY

Drug Name Classification Indication Contraindication Side Nursing Monitoring

and Mechanism Effects/Adverse Responsibilities Parameters
of Actions Reaction

Brand Name: Benzimidazole Short-term Hypersensitivity to  Headaches  Monitor V/S  V/S

treatment of other proton pump  Diarrhea  Monitor I&O  I&O
Prilosec erosive inhibitors. May  Abdominal Pain  Monitor pain  QRST
Inhibits hydrogen- esophagitis, increase risk  Nausea management  CBC with platelet
potassium symptomatic fractures,  Dizziness  Assist to the  Urinalysis
Generic Name: adenosine gastroesophageal gastrointestinal  Asthenia diagnostic tests  Pregnancy test
triphosphatase, an reflux disease infections. Hepatic  Vomiting  Chest Xray
Omeprazole
enzyme on the (GERD) poorly impairment, pts of  Constipation  Plain-abdomen
surface of gastric responsive to Asian descent.  Upper Xray
parietal cells. other treatment. respiratory tract  Sodium,
Dosage: Long-term infection Potassium
treatment of  Back pain electrolytes
pathologic  Rash  Dengue test
Therapeutic
hypersecretory  Cough  Stool Exam with
Effect: Increases
conditions, occult blood
Route: gastric pH,
treatment of active
reduces gastric
duodenal ulcer or
acid production
 active benign
gastric ulcer.

Frequency:
Duodenal ulcer,
gastric ulcer,
hypersecretory
conditions, H.
pylori eradication,
GERD, erosive
esophagitis
 DRUG STUDY

Drug Name Classification and Indication Contraindication Side Nursing Monitoring

Mechanism of Actions Effects/Adverse Responsibilities Parameter
Reaction s

Brand Name: Mechanism of Action:  It can be a  It is CNS: Vertigo,  Notify physician  Height
replacement contraindicate headache, or nursing staff  Weight
Hydrocort,  Enters target therapy in d to those paresthesias, immediately if  CBC
Alphosyl, cells and it binds adrenal cortical with allergy to insomnia, thrombosis is  Vital
Aquacort, o cytoplasmic insufficiency. any seizures, suspected Signs
Cortef, receptors;  Allergic States- components psychosis  Use minimal
Corteman, and initiates many severe or of the drug, dose for minimal
Solu-Cortef complex incapacitating fungal CV: Hypotension, duration to
reactions that allergic conditions infections, shock, minimize
are responsible  Hematologic amebiasis, hypertension and adverse effects.
Generic for it anti- Disorders- hepatitis B, heart failure  Do not give IM
Name: inflammatory, thrombocytopenic vaccinia, or secondary to fluid injections if
imunosuppressiv , purpura, varicella, and retention, patients
Hydrocortison e (gluocoticoid), thromboembolis
erythroblastopeni antibiotic- thrombocytopeni
e and salt-retaining m,
a. resistant c purpura.
(mineralocorticoi infection, thrombophlebitis,
d) actions. immune- fat embolism,
Dosage: suppression. cardiac
Drug Classification: arrythmias
 it is also
 Corticosteroids contraindicate secondary to
(short-acting) d to those electrolyte
Route:
 Hormone retention disturbances.
 Adrenocortical enemas, Hematologic:
Steroid intrarectal Na and fluid
Frequency: foam, with retention,
systemic hypokalemia,
fungal hypocalcemia,
infections, increased blood
recent sugar, increased
intestinal serum
surgery, cholesterol,
extensive decreased serum
fistulas. T3, and T4
levels.
 DRUG STUDY

Drug Name Classification and Indication Contraindication Side Nursing Monitoring

Mechanism of Effects/Adverse Responsibilities Parameters
Actions Reaction

Brand Name: Mechanism of  It is  It is  Dehydration  Assess fluid  Monitor BP

Action: indicated for contraindicated  Electrolyte status  Input and
Lasix treatment of in patients with imbalance  Monitor daily Output
 It works to edema anuria. It  Muscle weight
Generic Name: increase the associated should be Cramps  Assess and
Furosemide excretion of with used  Weakness monitor amount
Na+ and congestive cautiously in  Unusual and location of
Dosage: water by the heart failure, any patient tiredness edema, lung
kidneys by cirrhosis of with renal  Confusion sounds, skin
inhibiting the liver, and disease such  Severe turgor, and
Route: their renal as severe dizziness mucous
reabsorption disease, renal  fainting membranes
from the including the impairment or  drowsiness  Assess
proximal nephrotic renal failure.  unusual dry electrolytes:
Frequency:
and distal syndrome, in mouth/thirst potassium and
tubules, as adults and  nausea magnesium
well as the pediatric vomiting  Notify health care
loop of patients.  fast/irregular professional of
Henle. It  As the heartbeat thirst, dry mouth,
work as patient is lethargy
directly acts receiving
on the cells blood
of the
 nephron transfusion,
and furosemide
indirectly can help to
modifies the reduce the
content of vascular
the renal overload
filtrate. that may be
imposed by
Classification: the
 Diuretics additional
blood
volume
delivered
during
transfusion.
 DRUG STUDY

Drug Name Classification and Indication Contraindication Side Nursing Monitoring

Mechanism of Effects/Adverse Responsibilities Parameters
Actions Reaction

Brand Name: Mechanism of  Treatment of  It is Hypersensitivity:  Assess for history  CBC

Action: megaloblasti contraindicated Allergic reactions of allergy to folic  Monitor vital
Folvite c anemias with allergy to acid signs
 Required for due to sprue, folic acid Local: Pain and preparations;  HgB
Generic nucleoprotein discomfort at
Name: nutritional preparations; pernicious,  Hct
synthesis and deficiency, pernicious, injection site aplastic,  Schilling
Folic acid maintenance of pregnancy, aplastic, normocytic Tests
normal infancy, and normocytic anemias;  Monitor
erythorpoiesis childhood. anemias. lactation serum folate
Dosage: Drug Classification:  Test using levels and
Schilling test and serum
 Folic Acid serum vitamin vitamin B12.
 Vitamin B12 levels to rule
Route:
Supplemental out pernicious
anemia.
 Notify physician
Frequency: for any signs
adverse effects.
 DRUG STUDY

Drug Name Classification Indication Contraindication Side Nursing Monitoring

and Mechanism Effects/Adverse Responsibilities Parameters
of Actions Reaction

Brand Name: Mechanism of  It is indicated  It is  bone or joint  Notify physician if  BP

Action: to those with contraindicated pain there are any sign  HgB
Epoetin Alfa anemia for those with  General adverse effects  CBC
 It interacts secondary to acute feeling of  Interrupt  Monitor
Generic Name: directly with chronic kidney correction of tiredness or treatment if blood electrolyte
Erythropoietin the EPO disease and severe anemia weakness pressure counts.
receptor on chemotherapy or emergency  Heartburn of becomes
the blood cell -induced transfusion. belching uncontrollable
(RBC) anemia in  Shivering  Exclude other
Dosage:
surface, patients with causes of anemia
triggering the cancer. and give iron
activation of supplements
Route: several signal where
transduction appropriate.
pathways,  Assess patient’s
Frequency: resulting in BP.
the
proliferation
and terminal
differentiation
of erythroid
 precursor
cells and
providing
protection
from RBC
precursor
apoptosis. It
also works by
causing the
bone marrow
(soft tissue
inside the
bines where
blood is
made) to
make more
red blood
cells.

Drug
Classification:

Erythropoiesis-
stimulating
agents (ESAs).
 DRUG STUDY

Drug Name Classification Indication Contraindication Side Nursing Monitoring

and Mechanism Effects/Adverse Responsibilities Parameters
of Actions Reaction

Brand Name: Mechanism of  It is indicated  It is  Allergic - Routinely  Monitor liver

Action: to relieve mild contraindicate reaction, which monitor the function
Dymadon®, or moderate d for those can cause rash effectiveness  Urea
Lemsip®,  Paracetamol pain, such as who had had and swelling of  Electrolytes
Panadol®, has a central headaches, an allergic  flushing, low paracetamol  Creatinine
Panamax®, analgesic toothache or reaction to blood pressure by assessing  Monitor Vital
Tylenol® effect that is sprains, and paracetamol or and fast pain levels Signs
mediated reduce fevers any other heartbeat and fever
through caused by medicine, have reduction.
Generic Name: activation of illnesses such liver problems. - For patients
descending as colds and who are at
Paracetamol serotonergic flu. risk for
pathways. Paracetamol hepatotoxicity
Debate exists is often or renal
Dosage: about its recommended toxicity, the
primary site of as one of the nurse should
action, which first closely
may be treatments for monitor AST
inhibition of pain, as it's and ALT
Route: prostaglandin safe for most levels and
(PG) people to take BUN and
 synthesis or and side creatinine
through an effects are
active rare
Frequency: metabolite
influencing
cannabinoid
receptors.

Drug
Classification:

- Analgesic
and
Antipyretic
drugs.