- Fertilization is the process where a single sperm unites with an egg to form a
new human life.
- During sexual intercourse, approximately 300 million sperm enter the vagina. - Protective elements in the fluid surrounding sperm help many survive in the acidic vaginal environment. - Sperm must pass through the cervix, which opens during ovulation, facilitated by thinned cervical mucus. - Muscular uterine contractions aid sperm on their journey, although some are destroyed by the woman's immune system. - Half of the remaining sperm head for the empty fallopian tube, while the rest swim toward the tube containing the egg. - Tiny cilia in the fallopian tube push the egg toward the uterus, while sperm must surge against this motion to reach the egg. - Chemical changes in the reproductive tract make sperm hyperactive, aiding in their journey to the egg. - Only a few dozen sperm out of the original 300 million reach the egg, covered with a layer of cells called the corona radiata. - Sperm attach to specialized receptors on the egg's surface, releasing enzymes to burrow into the zona pellucida. - Inside the zona pellucida, the first sperm to make contact fertilizes the egg. - After fusion with the egg cell membrane, the egg releases chemicals to prevent other sperm from attaching. - The male and female genetic material join together, forming a unique genetic code—the zygote. - The zygote is swept toward the uterus by cilia in the fallopian tube, where it implants in the uterine lining to grow and mature for nine months until birth.