Presented the abstract as a poster during the FIP Pharmacy Practice Research Summer Meeting held at Granada, Spain on 3rd-4th July 2023.
Nasir A. A study on drug utilisation evaluation of Bronchodilators using a defined daily dose method. Pharmacy Education Journal [Internet]. 2023 Aug;23(5):23–24. Available from: https://doi.org/10.46542/pe.2023.235.138
Presented the abstract as a poster during the FIP Pharmacy Practice Research Summer Meeting held at Granada, Spain on 3rd-4th July 2023.
Nasir A. A study on drug utilisation evaluation of Bronchodilators using a defined daily dose method. Pharmacy Education Journal [Internet]. 2023 Aug;23(5):23–24. Available from: https://doi.org/10.46542/pe.2023.235.138
Presented the abstract as a poster during the FIP Pharmacy Practice Research Summer Meeting held at Granada, Spain on 3rd-4th July 2023.
Nasir A. A study on drug utilisation evaluation of Bronchodilators using a defined daily dose method. Pharmacy Education Journal [Internet]. 2023 Aug;23(5):23–24. Available from: https://doi.org/10.46542/pe.2023.235.138
Astudy on drug utilisation evaluation of
bronchodilators using a defined daily dose
method
Afreen Nasir
Acharya & BM Reddy College of Pharmacy, India
afreenn.official@gmail.com
Introduction: Drug therapy is crucial to promoting human
health by increasing the quality of life and extending lifespan.
A drug utilisation study is a method to assess and improve
drug use. The defined daily dose (DDD) concept is a drug
quantification approach. Drug utilisation, in terms of DDD,
aids in converting the available volume of medications into
medically relevant units, allowing estimations of the number
of people exposed to a certain medicine or class of medicines.
The unit DDD per 100 bed-days in a hospital context indicates
the proportion of inpatients who may receive a DDD. It is a
reasonably simple and affordable approach for comparing
medications in the same therapeutic class. DDD in
23FIP Pharmacy Practice Research summer meeting 2023
bronchodilators assists in discovering the consumption of
prescribed drugs and analysing the drug usage pattern. As the
rational burden of respiratory disease rises, so does the use
‘of medications such as bronchodilators in hospitalised
patients, Such research alded in the effective management of
bronchodilators in the ward.
Objectives: This study aimed to assess the drug utilisation of
broncho-dilating agents prescribed to patients admitted to
‘the General Medicine ward.
Methods: A prospective observation study was conducted six
‘months in ESIC MC-PGIMSR, Rajajinagar, Bengaluru. A total of
216 in-patients from the General Medicine ward who were
prescribed broncho-dilating agents were included in the
study. Patients’ case sheets were collected, and data were
entered in a self-designed date collection form. These data
were entered into the MS Excel sheet. Drugs were classified
according to ATC classification, and consumption of broncho-
dilating agents was calculated in terms of DDD & DDD/100
bed days, and descriptive statistical analysis was performed.
Results: During the study period, 216 patients were enrolled
and had an average length of 9.90 hospital stay days. The
highly utilised bronchodilator during the study period in the
‘general medicine ward was theophylline with 469.54
DDD/100 bed days, and its PDD:DDD was 4.35. The current
study found that the total consumption of broncho-dilating
‘agents in the general medicine ward was 2696.35 DDD; and
872.91 in terms of DDD/100 bed days.
Conclusions: This study concludes that the most common
reason for admission was respiratory system-related
complaints, and the most commonly _ prescribed
bronchodilators were ipratropium bromide and salbutamol in
2 fixed-dose combination. The study found that
bronchodilators were mostly prescribed as combination
therapy, with 87.36% of prescriptions comprising
combination therapy. The study population had a high
prevalence of hypertension and diabetes melitus, with
36.57% and 33.80% of patients, respectively, being known
cases, The study also found that the number of smokers and
alcoholics was higher than non-smokers and non-alcoholic.
Bronchodilators in a general medicine ward were classified
Using ATC classification. Theophylline was the most utilised
bronchodilator, with 46954 DDD/100-bed days. Total
consumption was 2696.35 DDD and 872.91 DDD/100 bed
days, indicating 872.91% of in-patients received 1 DDD of
bronchodilator on average dally. Methylxanthines were over-
utilised with a PDD:DDD ratio of 4.35 and 3.26 for
theophylline and etofylline tablets, respectively.
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