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Hazzard's
GERIATRIC MEDICINE
and GERONTOLOGY
EIGHTH EDITION
Hazzards
Geriatric Medicine
and Gerontology
Editors Mark A. SupianorMD
I). Keith Barnes, MD and Dottic Barnes Presidential
Jeffrey B. Halter, MD Endowed (.'hair in Medicine
Professor Emeritus Professor and Chief, Division of Geriatrics
Deportment of Internal Medicine University of Utah School of Medicine
Division ofGeriatric andPalliativeMedkine Executive Director, University of Utah Center on Aging
University of Michigan Salt lake City, Utah
Parkway Visiting Professor in Geriatrics
Department of Medicine .
Christine S. Ritchie, MD MSPH
Yong Loo Lin School of Medicine .
Kenneth L Minaker Endowed Chair in Geriatric Medicine
National University of Singapore .
Director Mongan Institute Center for Aging and Serious Illness
Ann Arbor, Michigan Professor of Medicine
Massachusetts General Hospital and
Joseph G. Ouslander, MD Harvard Medical School
Professor of Geriatric Medicine Boston, Massachusetts
Senior Advisor to the Dean tor Geriatrics
.
Charles E Schmidt College of Medicine Kenneth Schmader, MD
.
Professor ( Courtesy ), Christine E Lynn College of Nursing Professor of Medicine-Geriatrics
Florida Atlantic University Co- Director, Pepper Older Americans Independence ('enter
Boca Raton, Florida Duke University Medical Center
Editor- in-Chief, Journal of the American Geriatrics Society .
Director Geriatric Research Education and Clinical Center
Durham YA Health Care System
Stephanie Studenski,MD, MPH
Professor Emeritus
.
Durham North Carolina
New York Chicago San Francisco Athens London Madrid Mexico City
New Delhi Milan Singapore Sydney Toronto
Copyright © 2022 by McGraw Hill LLC. All rights reserved. Except as
permitted under the United States Copyright Act of 1976, no part of this
publication may be reproduced or distributed in any form or by any means, or
stored in a database or retrieval system, without the prior written permission
of the publisher.
ISBN: 978-1-26-046446-7
MHID: 1-26-046446-6
The material in this eBook also appears in the print version of this title:
ISBN: 978-1-26-046445-0, MHID: 1-26-046445-8.
All trademarks are trademarks of their respective owners. Rather than put a
trademark symbol after every occurrence of a trademarked name, we use
names in an editorial fashion only, and to the benefit of the trademark owner,
with no intention of infringement of the trademark. Where such designations
appear in this book, they have been printed with initial caps.
TERMS OF USE
Part I
Principles of Gerontology
1 Biology of Aging and Longevity
David B. Lombard, Richard A. Miller, Scott D. Pletcher
2 Demography and Epidemiology
Michelle C. Odden, Kendra D. Sims, Anne B. Newman
3 Immunology and Inflammation
Albert C. Shaw, Thilinie D. Bandaranayake
4 Psychosocial Aspects of Aging
Steven M. Albert, Cynthia Felix
5 Sex Differences in Health and Longevity
Steven N. Austad
6 Social Determinants of Health, Health Disparities, and Health Equity
Laura Block, W. Ryan Powell, Andrea Gilmore-Bykovskyi, Amy J. H. Kind
Part II
Principles of Geriatrics
SECTION A: Assessment
7 Decision Making and Advance Care Planning: What Matters Most
Daniel D. Matlock, Hillary D. Lum
8 Principles of Geriatric Assessment
David B. Reuben, Ryan J. Uyan, Valerie S. Wong
9 Mental Status and Neurologic Examination
James E. Galvin, Michelle M. Marrero
10 Assessment of Decisional Capacity and Competencies
Margaret A. Drickamer, Sarah Stoneking
11 Prevention and Screening
Ashwin A. Kotwal, Sei J. Lee
SECTION B: Age-Friendly Care Across Settings
12 Age-Friendly Care
Terry Fulmer, Maryama Diaw, Chaoli Zhang, Jinghan Zhang, Wendy Huang, Amy Berman,
Tara Asokan, Kedar S. Mate, Leslie Pelton
13 Geriatrics Around the World
Hidenori Arai, Jacqueline C. T. Close, Len Gray, Finbarr C. Martin, Luis Miguel Gutierrez
Robledo, Stephanie Studenski
14 Models of Hospital and Outpatient Care
Jonny Macias Tejada, Michael L. Malone
15 Emergency Department Care
Christopher R. Carpenter, Ula Hwang
16 Institutional Long-Term and Post-Acute Care
Joseph G. Ouslander, Alice F. Bonner
17 Community-Based Long-Term Services and Support, and Home-Based Medical Care
Jessica Colburn, Jennifer Hayashi, Bruce Leff
18 Transitions of Care
Elizabeth N. Chapman, Andrea Gilmore-Bykovskyi, Amy J. H. Kind
19 Value-Based Care
David J. Meyers, Heidi Wold, Joseph G. Ouslander
20 The Role of Social Workers
Ruth E. Dunkle, Jay Kayser, Angela K. Perone
21 The Patient Perspective
Preeti N. Malani, Erica S. Solway, Jeffrey T. Kullgren
SECTION C: Special Management Issues
22 Medication Prescribing and De-Prescribing
Paula A. Rochon, Sudeep S. Gill, Christina Reppas-Rindlisbacher, Nathan M. Stall, Jerry H.
Gurwitz
23 Substance Use and Disorders
Benjamin H. Han, Alexis Kuerbis, Alison A. Moore
24 Integrative Medicine and Health
Julia Loewenthal, Gloria Y. Yeh, Darshan H. Mehta, Peter M. Wayne
25 Patient-Centered Management of Chronic Diseases
Caroline S. Blaum, Aanand D. Naik
26 Legal Issues
Marshall B. Kapp
SECTION D: Surgical Management
27 Perioperative Care: Evaluation and Management
Shelley R. McDonald
28 Anesthesia
Leanne Groban, Chandrika Garner
29 Surgical Quality and Outcomes
Hiroko Kunitake
SECTION E: Nutrition
30 Nutrition Disorders, Obesity, and Enteral/Parenteral Alimentation
Dennis H. Sullivan, Larry E. Johnson, Jeffrey I. Wallace
31 Disorders of Swallowing
Nicole Rogus-Pulia, Steven Barczi, JoAnne Robbins
32 Oral Health
Joseph M. Calabrese, Judith A. Jones
SECTION F: Sensory Function
33 Low Vision: Assessment and Rehabilitation
Gale R. Watson, Katharina V. Echt
34 Hearing Loss: Assessment and Management
Su-Hua Sha, Kara C. Schvartz-Leyzac, Jochen Schacht
SECTION G: Gender and Sexuality
35 Sexuality, Sexual Function, and the Aging Woman
Monica Christmas, Kaitlyn Fruin, Stacy Tessler Lindau
36 Gynecologic Disorders
Thomas Clark Powell, Russell Stanley, Holly E. Richter
37 Sexuality, Sexual Function, and the Aging Man
J. Lisa Tenover, Alvin M. Matsumoto
38 Benign Prostate Disorders
Catherine E. DuBeau, Christopher D. Ortengren
Part III
Geriatric Conditions
39 Systems Physiology of Aging and Selected Disorders of Homeostasis
George A. Kuchel
40 Applied Clinical Geroscience
Sara E. Espinoza, Jamie N. Justice, John C. Newman, Robert J. Pignolo, George A. Kuchel
41 Managing the Care of Patients with Multiple Chronic Conditions
Stephanie Nothelle, Francesca Brancati, Cynthia Boyd
SECTION A: Geriatric Syndromes
42 Frailty
Luigi Ferrucci, Jeremy D. Walston
43 Falls
Stephen R. Lord, Jasmine C. Menant
44 Sleep Disorders
Armand Ryden, Cathy Alessi
45 Syncope and Dizziness
Ria Roberts, Lewis A. Lipsitz
46 Pressure Injuries
Joyce M. Black
47 Incontinence
Camille P. Vaughan, Theodore M. Johnson, II
48 Elder Mistreatment
Mark S. Lachs, Tony Rosen
SECTION B: Mobility
49 Muscle Aging and Sarcopenia
Alfonso J. Cruz-Jentoft
50 Mobility Assessment and Management
Valerie Shuman, Caterina Rosano, Jennifer S. Brach
51 Osteoporosis
Gustavo Duque, Mizhgan Fatima, Jesse Zanker, Bruce R. Troen
52 Osteoarthritis
Michele R. Obert, Ernest R. Vina, Jawad Bilal, C. Kent Kwoh
53 Hip Fractures
Ellen F. Binder, Simon Mears
54 Therapeutic Exercise
Kerry L. Hildreth, Kathleen M. Gavin, Christine M. Swanson, Sarah J. Wherry, Kerrie L.
Moreau
55 Rehabilitation
Cynthia J. Brown
SECTION C: Mentation
56 The Aging Brain
Luigi Puglielli
57 Cognitive Changes in Normal and Pathologic Aging
Bonnie C. Sachs, Brenna Cholerton, Suzanne Craft
58 Delirium
Matthew E. Growdon, Tanya Mailhot, Jane S. Saczynski, Tamara G. Fong, Sharon K.
Inouye
59 Dementia Including Alzheimer Disease
Cynthia M. Carlsson, Nathaniel A. Chin, Carey E. Gleason, Luigi Puglielli, Sanjay Asthana
60 Behavioral Symptoms of Dementia and Psychoactive Drug Therapy
Carol K. Chan, Constantine G. Lyketsos
61 Parkinson Disease and Related Disorders
Vikas Kotagal, Nicolaas I. Bohnen
62 Cerebrovascular Disease
Nirav R. Bhatt, Bernardo Liberato
63 Other Neurodegenerative Disorders
John Best, Howie Rosen, Victor Valcour, Bruce Miller
64 Traumatic Brain Injury and Chronic Traumatic Encephalopathy
Ann C. McKee, Daniel Kirsch
65 Major Depression
Whitney L. Carlson, William Bryson, Stephen Thielke
66 General Topics in Geriatric Psychiatry
Ellen E. Lee, Jeffrey Lam, Dilip V. Jeste
Part IV
Part V
In Fig. 5, the look-out man with his pole is also seen forward; the
crew are gathered round the mast to haul at the halyards, and get in
the sheets and braces; for now that the sail does not reach right
down to the deck, sheets have become indispensable. It will also be
remarked that the boom has been introduced to make the sail set
better. The amount of sheer given to the boat is enormous, although
the curve-in of the top of the stern is exceedingly attractive.
Assuming that the dimensions of the model are proportionate she
must have had precious little grip of the water, and if, when on an
expedition to the land of Punt, the Egyptians ever encountered a
beam wind, their ships must have made a terrible lot of lee-way. For
even a light breeze, coming at right angles to those overhanging
bows with no great draught amidships, would drive her head right off
the wind. The steersman would naturally stand to leeward, to get a
pull on his steering-thong or lanyard in order to luff her up, and
prevent her sagging too much to leeward. At a later date, when, as
we shall see, an oar was used each side for steering in place of only
one at the extreme stern, the helmsman stood on the lee side and
worked the lee steering oar. By reason of its size, this would have
some of the effects of the leeboards on a Thames Barge or
Dutchman.
Although these two models are the finest tomb group that have yet
reached England, yet others have been found at Sakkara, and
elsewhere, sometimes with a hull painted yellow and a cabin with an
awning painted to imitate leather, in which the proprietor, more
carefully made and of better wood than his sailors, sat with his box
by his side. Another boat model was of light papyrus with flower-
shaped prow and stern. It was painted green, and carried a light
shelter under which the owner usually stood.[4]
These ships of the Twelfth Dynasty have an additional interest for
us, since they belong to the time when Egypt was enjoying the fullest
prosperity, and had reached its highest degree of civilisation in its
capital of Thebes. But it is in the illustrations of ships afforded by
excavations in connection with the Temple of Deir-el-Bahari that we
find the most detailed information. The south wall of the middle
terrace of this building is most informative, depicting as it does the
naval expedition to the land of Punt. In Egyptian history various
expeditions are mentioned to Punt. One occurred as early as the fifth
Dynasty, for it is recorded in a tomb of a dynasty later. During the
eleventh Dynasty, a similar expedition was made under Sankh-kara,
and Ramases III. also sent an expedition. These last two voyages
are said to have started from a harbour on the Red Sea which was
reached from Koptos, probably the modern Kosseir, and to have
returned there.
Although it is now thought by some Egyptologists that Queen
Hatshopsitu did not send an expedition to Punt, but that she was
only copying the expedition of the eleventh Dynasty, and that these
Punt reliefs are merely replicas of other reliefs still to be discovered
in the older temple, depicting an expedition under Nebkheruna, yet it
is a doubtful point and by no means settled by critics.
But supposing these are the ships of the Egyptian Queen of the
eighteenth Dynasty, they are seen with fifteen oarsmen a side, whilst
two look-out men are standing forward in a kind of open-work
forecastle. The general shape of the ship by now has become
considerably modified. Whilst there is still considerable overhang
both at bow and stern, yet she is long on the waterline. The bow
resembles nothing so much as that of a modern gondola. There is a
beautiful line sweeping up aft to a raised poop with an ornamentation
curving gracefully inboard to another open-work castle or cabin.
These illustrations of the eighteenth Dynasty show how thoroughly
the Egyptians had mastered the art of shipbuilding. When a ship is
sailing on the sea, she is thrown up by the motion of the waters till
she rests pivoted on the crest of a wave. The middle of the ship is
thus supported, but the bow and stern, not being waterborne, have a
tendency to droop while the centre of the ship tends to bulge up.
This is technically known among naval architects as “hogging.” In the
case of ships with an enormous overhang, unsupported by water,
such as was the case of the Egyptian ships and is now the fashion
with our modern yachts, this hogging would need to be guarded
against. Only recently the writer saw on the south coast a modern
yacht with no beam but considerable length and overhang. She had
been badly built and the “hogging” was very noticeable a little
forward of amidships. Her skipper gave her a very bad name
altogether.
In the Hatshopsitu ships we see the “hogging” strain guarded
against by a powerful truss of thick rope. This truss leads from
forward, sometimes being bound round—undergirding—the prow:
sometimes it is made fast inside, perhaps to the deck or to the floors.
It then leads aft, being stretched on forked posts until it reaches the
mast, where it is wound round in a sort of clove-hitch, and then
continues aft again being stretched on other forked posts until it is
finally girded round the counter. This truss was as large as a man’s
waist, and has been calculated by Commander T. M. Barber of the
United States’ Navy to have been able to withstand a strain of over
300 tons.[5]
The manner of steering from the centre of the stern with one oar
has given way to that of using an oar on each quarter. Each oar rests
on a forked post rising above the head of the steersman who works
the oar with a thong loop. As already pointed out, it is noticeable that
he uses the lee steering oar always. It is probable that going to the
land of Punt, the prevailing North wind favoured them. But returning,
if the wind was foul, they would have to row. Even had they
understood the art of tacking at this time they would have had some
difficulty. As far as one can gather from the look of a ship of this kind,
as soon as ever the lee oar was pushed over so that she came up
into the wind, she would get into stays and not pay off on to the other
tack except with the aid of the oarsmen.
In these Punt pictures, too, will be noticed the fact that the rowers
have their oars in thongs instead of the later invention—pins or
rowlocks. These ships were certainly decked, but that was probably
only down the centre, for though we see the ship crowded with all
sorts of merchandise, yet the rowers’ bodies are only visible from the
knees upwards. They were probably placed on a lower platform.
Just as in the course of time the double and treble mast gave way
to the single spar, and the deep, narrow sail to the broad, shallow
square-sail, so later, about the year 1250 b.c., we find that the boom
was discarded, and therefore at any rate, by now, sheets must have
been introduced. But before we pass from Hatshopsitu’s ships
(about 1600 b.c.) let us examine the sail of that time. So much
confusion exists in the mind of many who see occasional pictures of
these early vessels that it may be well to make an effort to clear this
matter up. The yard was of two pieces lashed together in the middle;
the same statement applies to the boom. Pulleys not being yet
invented, the two halyards that raised the yard, led through two
empty squares formed by a framework of wood acting as fair-leads.
These halyards led aft, and being belayed well abaft the mast were
used as powerful stays to the latter. Let it be understood at once that
the boom remained fixed, being lashed to the mast by thongs. From
the top of the mast below the yard depended a series of topping lifts
about seventeen in number. These coming out from the mast at
varying angles spread over the whole length of the boom, and took
the weight of the latter, supporting also the sail and yard when
lowered. Contrary to the subsequent practice of the Greeks and
Romans, the yard was the spar that was raised or lowered by the
halyards. Thus, when sail was struck the two halyards would be
slacked off, the yard would descend on to the boom, the sail would