DLP DRAFT 3RD QUARTER

Republic of the Philippines
Department of Education
REGION III – CENTRAL LUZON
SCHOOLS DIVISION CITY OF MALOLOS
BULIHAN, CITY OF MALOLOS
CITY OF MALOLOS INTEGRATED SCHOOL
Sto. Rosario, City of Malolos
A DETAILED LESSON PLAN IN SCIENCE 10
Learning Area: SCIENCE 10 Modality: FACE-TO-FACE

Date of Observation: Quarter: THIRD
Name of Teacher: Position: PRACTICE TEACHER
I. OBJECTIVES
The learners demonstrated understanding of
A. Content Standards 1. The information stored in DNA as being used to make proteins.
The learners should be able to
B. Performance Standards Explain how protein is made using information from DNA; S10LT - IIId -37
C. Learning Explain how protein is made using information from DNA

Competencies /
Objectives
• describe the structure of DNA and RNA;
• identify the functions of DNA and RNA;
D. Unpacked Learning
Competency • compare and contratst DNA and RNA interms of structure, location and
function;
II. CONTENT
How protein is made using information from DNA
III. LEARNING
RESOURCES
A. References
1. Teacher’s Guide TG, pp.
Pages
2. Learners’ Materials Self-Learning Module (SLM) in Science 10, p. 1-16
Pages
3. Textbook Pages
4. Additional Materials
from the Learning
Resource portal
(LR)
B. Other Learning PowerPoint Presentation, Laptop, Chalk and board, Cards, Activity sheets, and
Resources Visual aids
TEACHER’S ACTIVITY STUDENT’S
ACTIVITY
IV. PROCEDURE Daily Class Routine
 Greetings:
“Good morning, Class.” “Good morning,

Ma’am.”
 Prayer:
“Dear Lord, make
“Before we begin, let’s have the opening prayer. us mentally alert. O
Who’s assigned to lead the prayer for today?” God, inspire us as
we start our classes
today. Increase our
wisdom and
develop our
character according
to what is good and
acceptable. We ask
this in Jesus’ name,
Amen.”
 Reminders:
“Pick up the trash under your table and arrange
your chairs properly before you sit down. Students proceeded to
tidy up their area and
“Sit properly, and If you want to answer, just arrange their seats.
raise your right hand.”
 Checking of Attendance:
“For the checking of attendance, Miss

Secretary, who are our absentees for today?”
“There are no absentees

for today, ma’am.”
The teacher marks the absent.
A. Reviewing the PRE- TEST
previous lesson or
presenting the new Directions: Choose the letter of the correct answer. Write
lesson your answers on a separate sheet
of paper.
(ELICIT)
1. It is a double-stranded nucleic acid.
a. amino acid b. protein c. DNA d. RNA
2. Which among the nitrogenous bases below can only be
found in RNA?
a. adenine b. cytosine c. guanine d. uracil
3. It is a large molecule that is composed of many
repeated sub-units.
a. calipher b. decipher c. monomer d. polymer
4. It acts as a storage of genetic information.
a. DNA b. RNA c. protein d. amino acid
5. It is a molecule that can undergo polymerization
thereby contributing constitutional units of
a macromolecule.
6. According to the base-pairing rule in DNA, which of
the choices below would be
complementary to this strand ** TATGCA ** ?
a. ATAGGT b. ATACCA c. ATACGT d. TATGCA
7. In DNA replication, adenine (A) always pairs with
_________.
a. Adenine (A) b. Cytosine (C) c. Guanine (G) d.
Thymine (T)
8. Which nitrogenous bases represent for the DNA
component?
a. A-T-C-U b. A-T-C-G c. T-U-C-G d. A-T-U-C
9. The chromosome can be found in the ________of the
cell.
a. cell wall b. cytoplasm c. mitochondria d. nucleus
10. In which organism you can find DNA molecules?
a. butterfly b. human c. tree d. all of the choices
11. This is the building block of protein that can link
together in a variety of processes to create
different forms.
a. fat b. glucose c. amino acid d. nucleic acid
12. The site of protein synthesis in the cell is
__________.
a. chloroplast b. mitochondrion c. nucleus d.
ribosome
13. Which sequence on the mRNA corresponds to the
DNA template “ATA”?
a. UAU b. ATA c. TUT d. UCU
14. Which of the following is attached to the transfer
RNA (tRNA) to build a growing chain of
polypeptide in the ribosomes?
15. It functions in the synthesis of protein from DNA in
the nucleus to the ribosomes.
a. mRNA b. tRNA c rRNA d. DNA
B. Establishing a purpose Before we start, I prepared a game.

for the lesson
(ENGAGE) This game is called “CHARADES”
Who knows this game?
The students will raise
their hands
Okay, class in this game I need two groups

consisting of 3 members.
The students will play
the game.
Leaders of each group will pick a word and act it out
while the members will guess what is being acted
upon by the leader.
You will be given 3 minutes to guess all the pictures.
The group with the highest number of correct

answers will be declared as winner.
Is that clear?
Yes ma’am!
Given pictures.
A representative from
1. ROPE each group will act out
2. EGG the given word and
3. HAIR members will guess it
4. FAMILY correctly
5. HALLOW BLOCKS
6. PUZZLE
C. Presenting examples/ NUCLEIC ACID
instances of the new
lesson Nucleic acids are high-molecular weight polymers
(ENGAGE) composed of chain nucleotides. Nucleic acids are
generally classified as information macromolecules,
due to their roles in the storage, transmission and
expression of genetic information. It has two types,
the DNA (Deoxyribonucleic Acid) and the RNA
(Ribonucleic Acid).
“How can we relate our cells to a vast library, where

each book represents DNA? Yes, Student A?”
Student A: “Our cells
are like a library, where
each book represents
our DNA containing
instructions for our
body's functions.
"Very Good, Student A! So, just like in a library

where each book holds valuable information, our
cells are like a vast library, and inside them, there are
countless "books" called DNA. DNA, short for
deoxyribonucleic acid, is like the special ink on
those pages that holds all the instructions for our Students listen
bodies. Just as a book has chapters with stories or attentively
instructions, DNA has genes that act like chapters,
giving directions on how to make the proteins our
bodies need to function properly.
Pyrimidine is one of the 2 classes of nitrogenous

bases found in the nucleic acids. It has three types,
namely: cytosine, thymine, and uracil. In DNA, the
pyrimidines are cytosine and thymine, while in
RNA, it has also cytosine, but the uracil replaces
thymine. Meanwhile, purine is the other class that

includes adenine and guanine, which participate also
in the DNA and RNA formation
“Why is pyrimidine like a foundation brick when

building with LEGO? Yes, Student B?”
Student B: “Pyrimidine
is like a foundation
brick in LEGO because
it's a basic block for
making DNA, which is
like instructions for our
bodies. It's like starting
with a strong base
before adding more
pieces.”
Very good, Student B!
Before we continue our discussion, I've hidden paper

pieces under your desks, and you'll have three
minutes to find their matching pairs.
The students started

searching for their
partners.
Based on the letters written on the paper you
retrieved from under the desk, what do you think
these letters mean and what do the paper pieces you
formed represent?
Student C: In my
opinion, these letters
represent the
nitrogenous bases, and
the assembled paper
Exactly right! Student, C! Okay, now let’s proceed pieces represent the base
to our discussion. pairs.
STRUCTURE OF DNA
Usually, the DNA is made up of molecules called
nucleotides. But what are they consist of? Each
nucleotide is made up of a phosphate group, a five-
carbon sugar called deoxyribose and a nitrogenous
base. The DNA molecules have antiparallel
structures (double-helix) that run in opposite
directions of one another.
The DNA (Deoxyribonucleic Acid) is a double-

stranded nucleic acid located in the nucleus of the
cell. It is referred as the “blueprint of life” acting as a
long-term storage of genetic information.
STRUCTURE OF RNA
Similar to DNA, RNA is also made up of molecules
known as nucleotides. Each molecule contains a
phosphate group, a five-carbon sugar called ribose,
and a nitrogenous base too. These are the four types
of nitrogenous bases according to their
complementary pairing:
The RNA (Ribonucleic Acid) is a single-stranded

nucleic acid that plays different roles in the
expression of information throughout the human
body.
“What do you think are the differences between

DNA and RNA? Anyone?”
Student D raise his/her

hand
Student D: “DNA is the

long-term blueprint,
while RNA is the
temporary messenger.
DNA stays in the
nucleus and gives
instructions, while RNA
carries those
instructions to where
they're needed in the
cell.”
“Now, in this table you can see the different types of

RNA”
All of these three types of RNA together with DNA

work to build the proteins that the body needs. Thus,
the DNA and RNA are intertwined with each other.
But how are the two different in their structures? Let
us examine the table below.
“Based on this table, what do you think are the

differences between the types of RNA? Yes, Student
E?”
Student E: “Based on
this table, mRNA
carries instructions from
DNA to make proteins,
tRNA brings amino
acids to the ribosome
during protein synthesis,
and rRNA helps form
the structure of
ribosomes.”
D. Discussing new “After learning about the DNA have you ever
concepts and wondered, how can the DNA result in a trait?”
practicing new skills
#1
(EXPLORE)
“So let’s have an example by playing a puzzle game,
this activity called 'Find Your Piece,' where I will
distribute puzzle pieces. Participants need to find the Student will perform the
matching parts of their puzzle pieces. Once a group activity.
completes their puzzle. The first group to complete
the object will post it on the board and explain their
knowledge about the formed object."
Puzzle Pictures:
“What do you observe about the picture that you’ve

formed?”
Student F: “Different
Eye colors”
“Very Good! why do you think we have different

eye colors?”
Student G: “Sir because

we have different type
of genes”
“Great! Your DNA has genetic information that

codes the color of your eyes. Your eye color is based
on the pigment that inside of your eyes. But to have
that pigment, you have genes which are the portion
of a DNA that can code for PROTEINS which help
to make that pigment”
“So now let’s talk about how DNA can lead to the
making of a protein, Do you have any idea what do
you call this process?”
Student H: “Protein
synthesis, Sir”
“Superb! Why do you think protein important in the

human body?”
Student I: “Transport,
Structure in acting as
enzymes that make all
kinds of materials, in
protecting the body.”
“Protein is essential for you to live”

E. Developing “Now let’s talk about the two major steps in protein
Mastery (Leads to synthesis.”
formative
Assessment) WISPHER THE KNOWLEDGE
(EXPLAIN)
"Now we will have an activity. This activity requires
two groups, with each group having 5
representatives."
Mechanics of the game.

1. The two groups will line up in the middle.
The last member in line will bring a piece of
paper and a ballpen.
2. The last member of each group will go to the
back to see the question and write down the
jumbled letters containing the answer.
3. I will give one minute to answer the question. Student will perform the
When the 1 minute is up and the word "GO" activity.
is heard...
4. Members can move to the line and pass the
question or the answer to the fourth member
until it reaches the first member.

5. The first member will go to the blackboard to
write down their answer.
NSCRRATTPNIOI- is the process that rewrites the

genetic code in the DNA into messenger RNA
(mRNA). It follows the base pairing principle,
except that in DNA, adenine pairs with thymine,
while in RNA adenine pairs with uracil.
SLTTRAIONSL- is the second step in the gene

expression wherein the codons (three nitrogen bases)
are translated. It is the process by which the
information in the mRNA is translated into the
sequence of amino acids in proteins.
“Great job everyone!! What did you observe about

the game that we had?”
Student J: “In the

activity we did, I
observed that we passed
our answers or
knowledge until it
“Very good! To be able to answer in the board you reached the last
have a step to answer the questions” group.”
“In protein synthesis, we have 2 major steps the first

one is transcription and the second is translation.
Take note that C comes first before L in the alphabet
so you can remember transcription comes first.
Transcription- is when we’re going to transcribe

the DNA into a message.
In cell the DNA is in the nucleus so therefore

there is a transcription in the nucleus. In the steps
of transcription an enzyme called RNA
polymerase will connect complementary RNA
bases to the DNA. These RNA bases are bonded
together to form a single stranded mRNA.
“Remember that m in mRNA strands for messenger.

Messenger RNA consist of a message made of RNA
that has been based on the DNA”
In eukaryotes, mRNA can get out of the nucleus.

The mRNA can go out of the nucleus into
cytoplasm where it’s going to attach to a
ribosome.
RIBOSOMES MAKE PROTEIN.
“Do you have any idea what is the meaning of r in
rRNA?”
“Nice! The ribosome is going to build our protein in

the next step called translation” Student K: “Ribosomal
RNA”
“Now do you have any idea what is the meaning of T

in tRNA?”
TRNA carries an amino acid. Amino acids is the

monomers for a protein. It is a building block for
protein. Student L: “Transfer,
Sir”
“Since we’re making proteins, we are going to need

those amino acids to build it.”
“What do you think can build if you have a bunch of

amino acids?”
All of these tRNA are looking for complementary

bases.
When tRNA brings in the amino acids, it reads Student M: “A protein”

the bases EXAMPLE OF COMPLEMENTARY
BASES IS PRESENTED BY THIS LETTERS
UAC
AUG
“Remember that its is doesn’t read on letter at a

time; it reads it in triplets” That’s called a CODON,
A sequence of three consecutive nucleotides in a

DNA or RNA molecule that codes for a specific
amino acid. Certain codons signal the start or end
of translation.
“One of these tRNAs contains a complementary

anticodon”
UAC represent anti codon. UAC is called
methionine.
“A tRNA with the UAC anticodon comes in to pair

with complementary AUG codon on the mRNA.”
It transfers the amino acid it carries, methionine.

The tRNA will eventually leave, but it will leave
behind its amino acid.
“Have you ever wondered how I can get the name
of the tRNA or AUG codon called methionine?
Now let’s take a look in codon chart”
You can see on a codon chart that the AUG codon

on the mRNA codes for methionine. AUG is also
considering a start codon as methionine is
typically going to be your first amino in proteins.
“Let’s try another example, try to answer that name

of this codon CCA”
“Remember that careful to use a codon chart for

mRNA codons”
“Very Good!! Proline how do you come up in that

answer?”
“Superb! Do you have any questions?”

Student N: “Proline,
Sir”
Student N explains
his/her idea.
In unison: None, sir.

F. Finding practical Try to imagine the scenario I will provide, and after,
applications of try to answer the following questions.
concepts and skills in
daily living
(EXTEND) Scenario:
David is a fitness enthusiast who is passionate about
optimizing his nutrition and exercise routine to
achieve his fitness goals. He recently learned about
the protein synthesis process in his biology class and
is intrigued by how it relates to his daily life.
David decides to apply his understanding of protein
synthesis to improve his fitness regimen and overall
health.
Guide Questions:
1. After a intense workout, David experiences
muscle soreness and fatigue. How does his
knowledge of protein synthesis inform his post-
workout recovery strategy? Student O:
David's knowledge of
protein synthesis
informs his post-
workout recovery
strategy by reminding
him to consume protein-

rich foods or shakes
shortly after exercise to
help his muscles repair
and grow, reducing
muscle soreness and
fatigue.
2. What protein sources might be most beneficial for

supporting muscle growth and recovery after
workouts?
Student P: Protein
sources that might be
most beneficial for
supporting muscle
growth and recovery
after workouts. He can
also choose from top-
quality protein sources
like eggs, fish, and dairy
to meet his nutritional
needs effectively.
To elaborate our topic for today, I prepared a game which
G. Making is the “DNA AND PROTEIN SYNTHESIS BINGO”
generalizations and
abstractions about the Objective:
lesson During the game session, students will identify the correct
(ELABORATE) words on their BINGO card.
Materials: (per student)

• 1 bingo card
• 25 bingo markers (I recommend using 25
pennies)
Procedures:
1. I will call out the questions.
2. From the question, determine the correct. Mark
your card appropriately. For example, if the
question is “It is a double-stranded nucleic acid.”,
you may mark your card only if you have "DNA"
3. The game winner is the first to
have 5 correct answers marked. The winner
should shout "Bingo!" to indicate a winning card.
Questions:
1. located in the nucleoplasm with DNA as the Answer key:
template
2. picks up amino acids in the cytoplasm to the 1. messenger RNA
ribosomes and matches them to the coded mRNA
2. transfer RNA
message
3. forms the important structural components of the 3. ribosomal RNA
ribosomes
4. has ribose as its pentose sugar 4. RNA
5. stores the genetic information
5. DNA
6. The fundamental building block of protein is
__________. 6. Amino acid
7. DNA and RNA have building blocks called
__________. 7. Nucleotide
8. __________ is one of the two classes of
8. Pyrimidine
nitrogenous bases that include cytosine, thymine,
and uracil. 9. __________ is one of the two classes 9. Purine
of nitrogenous bases that includes adenine and
guanine. 10. DNA
10. It is a double-stranded nucleic acid. 11. Protein Synthesis

11. It is the process by which polypeptide chains are
constructed from the coded combinations of single 12. Transcription
amino acids within the cell. 13. Translation
12. What is the process that rewrites the genetic code
in the DNA into messenger RNA (mRNA)? 14. base pairs
13. What is the process by which the information in
mRNA is translated into the sequence of amino acids 15. RNA
in proteins? 16. Guanine
14. C=G AND T=A are known as __________.
15. It is a single-stranded nucleic acid. 17. Double-helix strand
16. In DNA replication, cytosine (C) always pairs
with _________. 18. Deoxyribonucleic
17. The structure of DNA is a __________ strand. Acid
18. What does the acronym "DNA" represent? 19. Thymine
19. In DNA replication, adenine (A) always pairs
with _________. 20. Uracil
20. Which among the nitrogenous bases below can
only be found in RNA? 21. Polymer
21. It is a large molecule that is composed of many 22. Ribosome
repeated sub-units.
22. The site of protein synthesis in the cell is 23. Ribonucleic Acid
__________.
23. What does the acronym "RNA" represent? 24. Nucleus
24. The chromosome can be found in the
________of the cell.
H. Evaluating POST- TEST

Learning
Directions: Choose the letter of the correct answer.
(EVALUATE)
Write your answers on a separate sheet
of paper.
1. It is a double-stranded nucleic acid.
a. amino acid b. protein c. DNA d. RNA
2. Which among the nitrogenous bases below can
only be found in RNA?
a. adenine b. cytosine c. guanine d. uracil
3. It is a large molecule that is composed of many

repeated sub-units.
4. It acts as a storage of genetic information.
a. DNA b. RNA c. protein d. amino acid
5. It is a molecule that can undergo polymerization
thereby contributing constitutional units of a
macromolecule.
6. According to the base-pairing rule in DNA, which
of the choices below would be
complementary to this strand ** TATGCA ** ?
a. ATAGGT b. ATACCA c. ATACGT d. TATGCA
7. In DNA replication, adenine (A) always pairs with
_________.
a. Adenine (A) b. Cytosine (C) c. Guanine (G) d.
Thymine (T)
8. Which nitrogenous bases represent for the DNA
component?
a. A-T-C-U b. A-T-C-G c. T-U-C-G d. A-T-U-C
9. The chromosome can be found in the ________of
the cell.
a. cell wall b. cytoplasm c. mitochondria d. nucleus
10. In which organism you can find DNA
molecules?
a. butterfly b. human c. tree d. all of the choices
11. This is the building block of protein that can link
together in a variety of processes to create
different forms.
12. The site of protein synthesis in the cell is
__________.
a. chloroplast b. mitochondrion c. nucleus d.
ribosome
13. Which sequence on the mRNA corresponds to
the DNA template “ATA”?
a. UAU b. ATA c. TUT d. UCU
14. Which of the following is attached to the transfer
RNA (tRNA) to build a growing chain of
polypeptides in the ribosomes?
15. It functions in the synthesis of protein from DNA
in the nucleus to the ribosomes.
a. mRNA b. tRNA c rRNA d. DNA
I. Additional To apply the lesson, let’s have additional activities
Activities for for that.
application or
remediation List down examples of helpful mutations in health,
agriculture, and industrial fields. Explain each of
them briefly. Write your answer on a separate sheet
of paper.
That’s all for today's class. See you tomorrow.
In unison: Goodbye and

thank you, Ma’am Gia.
V.REMARKS
VI.REFLECTION
A. No. of learners who earned
80% on the formative
assessment
B . No. of learners who
require additional activities
for remediation
C. Did the remedial lessons
work? No. of learners who
have caught up with the class.
D. No. of learners who
continue to require
remediation
E. Which of my teaching
strategies worked well? Why
did this work?
F. What difficulties did I
encounter that my principal or
supervisor can help me solve?
G. What innovation or
localized materials did I use
to discover which I wish to
share with other teachers?
Prepared by:
Practice Teacher
Checked by:
MIRASOL B. SANDOVAL
Master Teacher I
Approved by:
NOVA B. SANTIAGO, EdD.

School Principal IV

Region III – Central Luzon
Schools Division of Bulacan
District of Bulakan
GEN. GREGORIO DEL PILAR INTEGRATED SCHOOL
Sta. Ana, Bulakan, Bulacan

Fb page: DepEd Tayo-Gen. Gregorio del Pilar Integrated School-501633
email: ggpesbulakan@gmail.com / 501633@deped.gov.ph

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A DETAILED LESSON PLAN IN SCIENCE 10

Learning Area: SCIENCE 10 Modality: FACE-TO-FACE

The learners should be able to

C. Learning Explain how protein is made using information from DNA

A DETAILED LESSON PLAN IN SCIENCE 10

“Good morning, Class.” “Good morning,

“For the checking of attendance, Miss

A DETAILED LESSON PLAN IN SCIENCE 10

“There are no absentees

A DETAILED LESSON PLAN IN SCIENCE 10

B. Establishing a purpose Before we start, I prepared a game.

Okay, class in this game I need two groups

You will be given 3 minutes to guess all the pictures.

The group with the highest number of correct

A DETAILED LESSON PLAN IN SCIENCE 10

“How can we relate our cells to a vast library, where

"Very Good, Student A! So, just like in a library

Pyrimidine is one of the 2 classes of nitrogenous

A DETAILED LESSON PLAN IN SCIENCE 10

thymine. Meanwhile, purine is the other class that

“Why is pyrimidine like a foundation brick when

Very good, Student B!

Before we continue our discussion, I've hidden paper

The students started

A DETAILED LESSON PLAN IN SCIENCE 10

The DNA (Deoxyribonucleic Acid) is a double-

A DETAILED LESSON PLAN IN SCIENCE 10

The RNA (Ribonucleic Acid) is a single-stranded

“What do you think are the differences between

Student D raise his/her

Student D: “DNA is the

“Now, in this table you can see the different types of

All of these three types of RNA together with DNA

A DETAILED LESSON PLAN IN SCIENCE 10

“Based on this table, what do you think are the

A DETAILED LESSON PLAN IN SCIENCE 10

“What do you observe about the picture that you’ve

“Very Good! why do you think we have different

Student G: “Sir because

“Great! Your DNA has genetic information that

A DETAILED LESSON PLAN IN SCIENCE 10

“Superb! Why do you think protein important in the

“Protein is essential for you to live”

Mechanics of the game.

A DETAILED LESSON PLAN IN SCIENCE 10

until it reaches the first member.

NSCRRATTPNIOI- is the process that rewrites the

SLTTRAIONSL- is the second step in the gene

“Great job everyone!! What did you observe about

Student J: “In the

“In protein synthesis, we have 2 major steps the first

Transcription- is when we’re going to transcribe

A DETAILED LESSON PLAN IN SCIENCE 10

In cell the DNA is in the nucleus so therefore

“Remember that m in mRNA strands for messenger.

In eukaryotes, mRNA can get out of the nucleus.

“Nice! The ribosome is going to build our protein in

“Now do you have any idea what is the meaning of T