N141 Pharmacology

Pharmacology- Definitions- Week 1

Match each definition with its corresponding term- Note: Not all terms will be used.
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A. Synergistic
B. additive
C. enterohepatic circulation
D. first-pass effect
E. peak effect
F. onset of action
G. maintenance therapy
H. palliative therapy
I. tolerance
J. dependence
K. idiosyncratic
L. duration
M. generic name
N. trade name
O. carcinogenic
P. teratogenic
Q. mutagenic

1. ___N____ Also known as the proprietary name of a drug

2. ___L_____ The length of time that a drug concentration is sufficient to elicit a therapeutic response.
3. ____E_____ The time it takes for a drug to reach its maximum therapeutic response in the body.
4. ___F_____ The time it takes for drug to elicit a therapeutic response
5. ___J_____ A physiologic or psychological need for a drug
6. ___I_____ A decreasing response to repeated drug doses
7. ____A_____ Drug interaction where the drugs interact in such a way that their combined effects are
greater than the sum of the effects for each drug given alone. Potentiate the effect – two different
mechanisms of action.
8. ___B_____ Drug interaction in which the effect of a combination of two or more drugs with similar
actions is greater than or equal to when the drug is given alone.
9. ____P____ These drug effects result in structural defects in the unborn fetus.
10. _Q______ These drug effects are permanent changes in the genetic composition of living
organisms.
11. __O_____ These drug effects cause cancer.
12. ___G____ Drug therapy used for the treatment of chronic illnesses
13. ___H____ Therapy that is used to make a patient as comfortable as possible, and often used in
the end stages of an illness
14. __K_____ A genetically determined abnormal response to ordinary doses of a drug
15. ____D____ The initial metabolism in the liver of a drug that is absorbed from the gastrointestinal
tract, before the drug reaches systemic circulation through the blood stream
 N141 Pharmacology

References

Adams, M., Urban, C. Q., Sutter, R. E., El-Hussein, M., & Osuji, J. (2020). Pharmacology for

nurses: A pathophysiological approach. Toronto: Pearson Canada.

Roell, K. R., Reif, D. M., & Motsinger-Reif, A. A. (2017). An Introduction to Terminology and

Methodology of Chemical Synergy—Perspectives from Across Disciplines. Frontiers

in Pharmacology, 8. doi:10.3389/fphar.2017.00158