Code No: 248AA R17

JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD

B. Pharmacy IV Year II Semester Examinations, September-2021
BIOSTATISTICS AND RESEARCH METHODOLOGY
JN
Time: 3 Hours Max. Marks: 75
Answer any Five Questions
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All Questions Carry Equal Marks
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1. What are called measures of central tendency? List them. How the R and S.D are
calculated for a data derived for pharmaceutical formulation. Write your answer with
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suitable illustration. [15]

2. Discuss the following term with respect to biostatistics.

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a) Sample
b) Population
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c) Large sample
d) Small sample
e) Null hypothesis [15]
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3. Explain in detail about one-way ANOVA and two-way ANOVA in calculating the
level of significance and prove the hypothesis. [15]
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4. Write short notes on the following.
a) Wilcoxon Rank Sum Test
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b) Mann-Whitney U test
c) Kruskal-Wallis test. [5+5+5]

5. Elaborate the application of SPSS software in the clinical trails of pharmaceutical

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products. Write your answer with graphs and illustration. [15]

6. What is the need for research, need for design of experiments, experiential design
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techniques including plagiarism in pharmaceutical research? Write its importance.
[15]
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7. Highlights the application of
a) Histogram,
b) Pie Chart,
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c) Cubic Graph. [5+5+5]
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8. Give a short note on
a) Central composite design
b) Historical design
c) Optimization Techniques. [5+5+5]

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