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Biology: Science for Life with Physiology, 4e (Belk)
Chapter 9 Genetically Modified Organisms: Gene Expression, Mutation, and Cloning

1) A DNA molecule consists of


A) amino acids.
B) nucleotides.
C) fatty acid chains.
D) polysaccharides.
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

2) Which of the following pairs with adenine in a DNA molecule?


A) cytosine
B) thymine
C) uracil
D) guanine
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

3) A sequence of DNA codes for a


A) protein.
B) lipid.
C) monosaccharide.
D) nucleotide.
Answer: A
Diff: 2
Topic: 9.1
Skill: Conceptual

4) The structure of a protein is determined by


A) the number of amino acids it contains.
B) the sequence of the amino acids it contains.
C) the function of the nucleic acids it contains.
D) the number of fatty acids it contains.
Answer: B
Diff: 2
Topic: 9.1
Skill: Factual

1
Copyright © 2013 Pearson Education, Inc.
5) A molecule of RNA (ribonucleic acid) contains the bases
A) adenine, guanine, thymine, and uracil.
B) uracil, adenine, guanine, and adenosine.
C) thymine, adenine, guanine, and cytosine.
D) adenine, guanine, cytosine, and uracil.
Answer: D
Diff: 1
Topic: 9.1
Skill: Factual

6) Which molecule remains in the nucleus during protein synthesis?


A) DNA
B) tRNA
C) mRNA
D) rRNA
Answer: A
Diff: 1
Topic: 9.1
Skill: Factual

7) The sequence of events in the process of protein synthesis is usually


A) Protein → RNA → DNA.
B) RNA → DNA → protein.
C) DNA → RNA → protein.
D) RNA → protein → DNA.
Answer: C
Diff: 2
Topic: 9.1
Skill: Conceptual

8) Which of the following complementary base pairings occur between DNA and RNA?
A) A to T and C to G
B) T to C and A to G
C) G to C and A to U
D) C to U and A to T
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

9) The process of copying a sequence of DNA nucleotides into a complementary sequence of RNA
nucleotides is called
A) translation.
B) mutation.
C) transcription.
D) excision.
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual
2
Copyright © 2013 Pearson Education, Inc.
10) The RNA molecule that carries the sequence of nucleotides needed to determine the order of amino
acids in a protein is
A) transfer RNA.
B) ribosomal RNA.
C) messenger RNA.
D) translator RNA.
Answer: C
Diff: 2
Topic: 9.1
Skill: Conceptual

11) RNA polymerase binds to the ________ to begin the process of transcription.
A) promoter
B) structural gene
C) codon
D) anticodon
Answer: A
Diff: 1
Topic: 9.1
Skill: Factual

12) Which of the following is not directly involved in the process of translation?
A) ribosome
B) tRNA
C) mRNA
D) DNA
Answer: D
Diff: 2
Topic: 9.1
Skill: Conceptual

13) The rate of production of cellular proteins within each cell is regulated through which of the
following?
A) redundancy in the genetic code
B) frameshift mutations
C) gene expression
D) ambiguity in the genetic code
Answer: C
Diff: 2
Topic: 9.1
Skill: Factual

3
Copyright © 2013 Pearson Education, Inc.
14) Milk production in modern dairy cows has been dramatically increased because of
A) the insertion of Ti plasmids in the cow genome.
B) recombinant bovine growth hormone.
C) frameshift mutations in the DNA of the cows.
D) the use of gene guns to insert rBGH genes into the mammary tissues of cows.
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

15) Which of the following is found in the nucleotides of DNA but NOT in RNA?
A) a sugar
B) a phosphate group
C) deoxyribose
D) a nitrogen-containing base
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

16) RNA differs from DNA in that RNA


A) is contained in the nucleus.
B) doesn't contain a sugar.
C) is single-stranded.
D) takes part in transcription.
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

17) When genes are copied (in transcription), the resulting copy is in the form of a
A) complementary strand of DNA.
B) strand of mRNA.
C) molecule of tRNA.
D) palindrome.
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

4
Copyright © 2013 Pearson Education, Inc.
18) If the process of protein synthesis in a cell is analogous to a politician's speech being written down
by a reporter and then converted into a different language before being published, then the initial step
(being written down by a reporter) corresponds to
A) transcription.
B) translation.
C) genetic recombination.
D) cloning.
Answer: A
Diff: 2
Topic: 9.1
Skill: Conceptual

19) The nucleotide sequence on a section of DNA where transcription begins is called a
A) polymerase.
B) palindrome.
C) promoter.
D) codon.
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

20) Which of the following serves as the template during transcription?


A) DNA
B) mRNA
C) tRNA
D) polymerase
Answer: A
Diff: 1
Topic: 9.1
Skill: Conceptual

21) Which of the following serves as the template during translation?


A) DNA
B) mRNA
C) tRNA
D) polymerase
Answer: B
Diff: 1
Topic: 9.1
Skill: Conceptual

5
Copyright © 2013 Pearson Education, Inc.
22) Ribosomes are made of subunits that are composed of
A) mRNA and DNA.
B) tRNA and mRNA.
C) rRNA and proteins.
D) DNA and proteins.
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

23) What is the function of tRNA molecules during translation?


A) They unzip double-stranded mRNA.
B) They serve as the starting point for RNA polymerase.
C) They carry amino acids to the ribosome.
D) They encode the instructions for protein synthesis.
Answer: C
Diff: 1
Topic: 9.1
Skill: Conceptual

24) Which of the following always contain three nucleotides?


A) tRNA
B) an anticodon
C) mRNA
D) ribosome
Answer: B
Diff: 1
Topic: 9.1
Skill: Conceptual

25) What type of bond is formed between amino acids at the ribosome during translation?
A) peptide
B) ester
C) phosphodiester
D) hydrogen
Answer: A
Diff: 1
Topic: 9.1
Skill: Factual

26) What signal when present at the ribosome causes protein synthesis to end?
A) DNA
B) tRNA
C) a stop codon
D) RNA polymerase
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

6
Copyright © 2013 Pearson Education, Inc.
27) Which amino acid always begins a polypeptide (protein) during translation?
A) valine
B) phenylalanine
C) methionine
D) arginine
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

28) When a mutation results in no significant change in the production of a functional protein, it's called
a
A) frameshift mutation.
B) substitution mutation.
C) normal mutation.
D) neutral mutation.
Answer: D
Diff: 1
Topic: 9.1
Skill: Conceptual

29) Activators present near a gene that can be "turned on" will result in
A) increased transcription.
B) decreased gene expression.
C) unwinding of the DNA double helix.
D) a shift in the reading frame.
Answer: A
Diff: 1
Topic: 9.1
Skill: Factual

30) Which of the following would allow gene expression to proceed?


A) X-chromosome inactivation
B) an increase in proteases
C) an increase in repressor proteins
D) a reduction in nucleases
Answer: D
Diff: 1
Topic: 9.1
Skill: Conceptual

31) A double-stranded DNA molecule that has 22% guanine will have
A) 22% thymine.
B) 22% cytosine.
C) 44% adenine.
D) 48% thymine.
Answer: B
Diff: 2
Topic: 9.1
Skill: Conceptual
7
Copyright © 2013 Pearson Education, Inc.
32) Imagine that a mutation in a DNA molecule results in the codon CCU being changed to CCC. Both
of these codons code for proline. The fact that more than one codon can code for the same amino acid is
referred to as
A) the ambiguity of the genetic code.
B) the redundancy of the genetic code.
C) the universality of the genetic code.
D) mutations in the genetic code.
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

33) A point mutation results in the incorporation of a new amino acid in a protein. Which of the
following would be the most likely result?
A) an incomplete protein that still functions normally
B) an altered protein, which could result in a genetic disease
C) two proteins produced instead of one
D) no change to the function of the protein
Answer: B
Diff: 2
Topic: 9.1
Skill: Conceptual

34) Which of the following could be incorporated into a protein?


A) alanine
B) ribonucleic acid
C) thymine
D) uracil
Answer: A
Diff: 3
Topic: 9.1
Skill: Conceptual

35) Gene regulation in eukaryotic cells includes


A) activators that help RNA polymerase bind to the promoter.
B) repressors that prevent DNA polymerase from binding.
C) activation of the X chromosome.
D) degradation of nucleases by mRNA.
Answer: A
Diff: 2
Topic: 9.1
Skill: Conceptual

8
Copyright © 2013 Pearson Education, Inc.
36) If a DNA sequence of a gene reads, in part, TAACAGGTCA, what is the sequence of the
complementary strand of DNA?
A) ATTGTCCAGT
B) AUUGUCCAGU
C) UUACAGGUCC
D) CTTGTGGACC
Answer: A
Diff: 2
Topic: 9.1
Skill: Conceptual

37) As shown in this figure, which of the following is a difference between DNA and RNA?
A) the presence of a nitrogen-containing base
B) the presence of a phosphate group
C) the type of sugar present
D) the presence of guanine
Answer: C
Diff: 1
Topic: 9.1
Skill: Factual

9
Copyright © 2013 Pearson Education, Inc.
10
Copyright © 2013 Pearson Education, Inc.
38) Which of the following pairs includes items that aren't analogous according to this figure?
A) protein; cake
B) amino acids; flour, sugar, and eggs
C) tRNA; copy of recipe
D) genome in nucleus; cookbook on shelf
Answer: C
Diff: 1
Topic: 9.1
Skill: Conceptual

39) What is the sequence of the mRNA made from the gene TTACAGGTCC?
A) UUACAGGUCC
B) AATGTCCAGG
C) AAUGUCCAGG
D) GGAGTGGACC
Answer: C
Diff: 2
Topic: 9.1
Skill: Conceptual

40) Which of these is a polymer made of nucleotides?


A) nuclease
B) mRNA
C) proline
D) RNA polymerase
Answer: B
Diff: 1
Topic: 9.1
Skill: Factual

11
Copyright © 2013 Pearson Education, Inc.
41) Which of the following "unzips" the double helix of DNA?
A) an anticodon
B) mRNA
C) tRNA
D) RNA polymerase
Answer: D
Diff: 1
Topic: 9.1
Skill: Conceptual

42) As a result of a frameshift mutation,


A) one or two nucleotides are added or deleted in a DNA strand.
B) amino acids are assembled into normal, functional proteins.
C) the DNA is always modified in such a way that protein synthesis is prevented.
D) the substitution of one amino acid for another with similar chemical properties has no effect on
protein synthesis.
Answer: A
Diff: 2
Topic: 9.1
Skill: Conceptual

43) Recombinant proteins refer to proteins that have been made in which manner?
A) from chemicals in the lab
B) by genetically modified bacteria
C) more potent or more highly concentrated before their use
D) directly from deoxyribonucleic acids, thus bypassing transcription and translation
Answer: B
Diff: 1
Topic: 9.2
Skill: Factual

44) Which statement best describes how the FDA regulates the food industry?
A) All new foods developed by industry, whether they contain new products or old products, are put
through a rigorous testing program by the FDA.
B) Newly developed foods or food additives must be certified safe by the FDA before they can be
marketed to the public.
C) Foods must be clearly labeled in accordance with FDA guidelines to indicate whether they're
naturally occurring or genetically modified food products.
D) New foods can be marketed without FDA approval until there is a clear health issue with the food.
Answer: B
Diff: 2
Topic: 9.2
Skill: Conceptual

12
Copyright © 2013 Pearson Education, Inc.
45) All the genes in an organism constitute its
A) palindrome.
B) genome.
C) genetic code.
D) reading frame.
Answer: B
Diff: 1
Topic: 9.2
Skill: Factual

46) The GRAS designation made by the FDA stands for


A) "genetic research and support."
B) "genome recognized and studied."
C) "genetically recombined and synthesized."
D) "generally regarded as safe."
Answer: D
Diff: 1
Topic: 9.2
Skill: Factual

47) Which of the following foods or food ingredients come under the FDA jurisdiction for ensuring food
safety?
A) vitamin tablets
B) cheese
C) sirloin steaks
D) chicken wings
Answer: B
Diff: 2
Topic: 9.2
Skill: Conceptual

48) The "highly specific molecular scissors" that cut DNA are called
A) plasmids.
B) anticodons.
C) codons.
D) restriction enzymes.
Answer: D
Diff: 2
Topic: 9.2
Skill: Factual

49) In genetics, palindromes refer to


A) the types of DNA sequences that are cut out by restriction enzymes.
B) the A-T complementary bases of DNA.
C) the C-G complementary bases of DNA.
D) the A-U base pairing between DNA and mRNA.
Answer: A
Diff: 2
Topic: 9.2
Skill: Factual
13
Copyright © 2013 Pearson Education, Inc.
50) The molecular structure that geneticists use to insert foreign DNA into a recipient bacterial cell
where it can be replicated is called a(n)
A) codon.
B) anticodon.
C) genome.
D) plasmid.
Answer: D
Diff: 1
Topic: 9.2
Skill: Factual

51) Which of the following is least likely to be genetically modified?


A) microwave popcorn
B) potato chips
C) a candy bar
D) a head of broccoli
Answer: D
Diff: 2
Topic: 9.3
Skill: Conceptual

52) Genetically modifying crop plants can do which of the following?


A) decrease pesticide resistance in the plants.
B) make the plants more resistant to freezing.
C) reduce the amount of fat in the plants.
D) increase the incidence of galls in the plants.
Answer: B
Diff: 1
Topic: 9.3
Skill: Factual

53) Genetically modified foods have resulted in


A) rice that allows greater synthesis of vitamin A.
B) calorie-free potato chips.
C) a tomato that tastes like a melon.
D) lettuce that doesn't require water to grow.
Answer: A
Diff: 2
Topic: 9.3
Skill: Conceptual

14
Copyright © 2013 Pearson Education, Inc.
54) A recombinant Ti plasmid can be used to
A) insert genes from any source into a bacterium.
B) insert bacterial genes into a human.
C) insert genes from any source into a plant.
D) remove specific genes from a plant.
Answer: C
Diff: 1
Topic: 9.3
Skill: Conceptual

55) The possibly harmful environmental effects of GM foods include which of the following?
A) the decreased use of herbicides when GM foods are herbicide-resistant
B) the transfer of genetically modified genes to weedy relatives
C) the reduction of genetic diversity in all crops
D) an increase in allergic reactions in sensitive humans
Answer: B
Diff: 1
Topic: 9.3
Skill: Factual

56) Genetically modified tomatoes have been designed with which purpose in mind?
A) improving absorption of vitamins in the human body
B) continuing growth even after temperatures fall below freezing
C) killing insect pests on contact
D) having a longer shelf life in grocery stores
Answer: D
Diff: 1
Topic: 9.3
Skill: Factual

57) The β-carotene was inserted into GM golden rice to allow a person to
A) better synthesize proteins in the body.
B) see better under low light conditions.
C) more efficiently digest his or her starchy diet.
D) better synthesize vitamin A in the body.
Answer: D
Diff: 1
Topic: 9.3
Skill: Factual

58) The Ti plasmid originated from


A) the baker's yeast Saccharomyces cerevisiae.
B) the bacterium Agrobacterium tumefaciens.
C) the fungus Candida albicans.
D) the bacterium E. coli.
Answer: B
Diff: 1
Topic: 9.3
Skill: Factual

15
Copyright © 2013 Pearson Education, Inc.
59) What are genetically modified organisms (GMOs) also called?
A) artificial crop plants
B) artificially selected organisms
C) transgenic organisms
D) mutant crop plants
Answer: C
Diff: 1
Topic: 9.3
Skill: Factual

60) Approximately ________ of the foods in American grocery stores contain at least small amounts of
GMOs.
A) less than 10%
B) 25%
C) 50%
D) over 75%
Answer: C
Diff: 2
Topic: 9.3
Skill: Factual

61) To what does the "Ti" in Ti plasmid refer?


A) tumor inducing
B) transcription initiating
C) translation initiating
D) tumefaciens inclusion
Answer: A
Diff: 1
Topic: 9.3
Skill: Factual

62) Plant galls are


A) tumors caused by Ti plasmids in nature.
B) the result of neutral mutations.
C) pellets of foreign DNA inserted into the plants with a gene gun.
D) transgenic organisms containing foreign DNA of plant origin.
Answer: A
Diff: 1
Topic: 9.3
Skill: Factual

63) Roundup Ready soybean plants


A) produce fewer amino acids than regular soybean plants.
B) are extremely sensitive to herbicides but have a greater yield of soybeans.
C) have been modified to resist certain chemicals applied by farmers to control weeds.
D) manufacture very high levels of β-carotene.
Answer: C
Diff: 1
Topic: 9.3
Skill: Conceptual
16
Copyright © 2013 Pearson Education, Inc.
64) Data from the Human Genome Project might help scientists
A) understand who might be susceptible to certain diseases.
B) clone humans more easily.
C) understand the effects of genetically modified foods on the human body.
D) cure most human diseases.
Answer: A
Diff: 1
Topic: 9.4
Skill: Factual

65) The raw data from the human genome project consists of
A) the order of the bases A, T, G, and C in human DNA.
B) a list of all the genes expressed in each human cell type.
C) the disease conditions associated with each human chromosome.
D) the length of the DNA molecule making up each human chromosome.
Answer: A
Diff: 1
Topic: 9.4
Skill: Factual

66) Which of the following is an example of gene therapy?


A) replacing a failing heart with a new heart from a genetically matched donor
B) injecting human factor VIII protein into hemophiliacs with a defective factor VIII gene
C) infecting a cystic fibrosis patient with a virus carrying a working copy of the cystic fibrosis gene
D) providing therapeutic drugs to a patient experiencing high blood pressure
Answer: C
Diff: 2
Topic: 9.4
Skill: Conceptual

67) Which type of disease condition would most likely be successfully treated by gene therapy?
A) a disease caused by a nonfunctional enzyme in the body
B) a disease caused by excess fat intake
C) a disease caused by bacterial infection
D) a cancer caused by uncontrolled cell division
Answer: A
Diff: 2
Topic: 9.4
Skill: Conceptual

68) The undifferentiated cells that can be used in therapeutic cloning are
A) plasmid cells.
B) stem cells.
C) somatic cells.
D) transgenic cells.
Answer: B
Diff: 1
Topic: 9.4
Skill: Factual
17
Copyright © 2013 Pearson Education, Inc.
69) Therapeutic cloning aims to produce ________ from stem cells.
A) healthy tissues
B) genomes
C) model organisms
D) reproductive clones
Answer: A
Diff: 1
Topic: 9.4
Skill: Factual

70) The famous sheep "Dolly" was the result of


A) therapeutic cloning.
B) the Human Genome Project.
C) stem cell research.
D) nuclear transfer.
Answer: D
Diff: 3
Topic: 9.4
Skill: Conceptual

18
Copyright © 2013 Pearson Education, Inc.
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ÄITI

Jos olen poissa, olet vierelläin, sa seuraat teitäni mun silmin


suruisin. En sulle mitään kertonut, mut kuitenkin sun silmäs
kaiken tiesivät, ma näin.

Voi äiti, kaiken olen pettänyt,


sa mitä kerran toivoit ylpein sydämin,
ja petän uudelleen, — mut kuitenkin
mua rakastat, et mua hyljännyt.

Et tuomitse, ma vaikka pahoin teen.


Sen tiedän: puolestani paljon rukoilet
ja joka aamu toivot uudelleen.
Sa itket salaa vain, mut mulle hymyilet.

Et tuomita voi, sillä tiedäthän:


on sydämeni sairas, kovin levoton.
Sa tiedät kohtaloni, miten käynyt on —
Mun toivot kerran rauhan löytävän.

Voi äiti, tiedä, sua rakastan.


Muut ristiinnaulitsevat, sinä siunaat vain
ja anteeks annat, kuljet rinnallain.
Voi äiti, tiedä, sua rakastan.

Muu hämärtyi ja sammui multa pois,


vain rakkautes taivas rajaton
mun tieni yllä valoisana on.
Sun hyvyyttäsi unhoittaako vois —
RANNALLA

Mereltä tuulee. Kävelen rantaa.


Saaria ei näy aavalla.
Joskus tuuli korviini kantaa
tiiran huutelun kaukana.

Mereltä tuulee. Kävelen rantaa.


Rantakukka taipuu tuulessa.
Autuus on ulapan tuulen antaa
sydämeen asti suudella.

Mereltä tuulee. Ulappa avoin


kutsuu, kun tullut on hämärä.
Sieluni harhaa tiiran tavoin
jossakin kaukana merellä.
OTA MUN KÄDESTÄNI KIINNI

Elämäni on lehti, jota tuuli nopeasti kuljettaa.


Rakas, ota mun kädestäni kiinni!
Ma pelkään kylmyyttä ja yksinäisyyttä — kuolemaa.

Painajaisunet mua ahdistavat ja levottomuus ajaa.


Rakas, ota mun kädestäni kiinni
ja saata mua matkalla kohti tuntematonta rajaa.

Ma pelkään kylmyyttä ja yksinäisyyttä — kuolemaa.


Rakas, ota mun kädestäni kiinni!
Ma vapisen. Mua virran nopeus kammottaa —
SISARELLE

Hyvin silmin katselit silmiini mun kätes lempeä viipyen


kädessäin. Minä himmeän, avaran taivaan näin ja valkeat
tähdet ylläsi sun.

Ihan hiljaa ja huomaamatta vaan


sinä hengitit auki sydämein
kuin perhosen kotelokuorestaan,
sinä vieras äsken, nyt sisarein.

Sinä tiesit: toisen sydämen


kivikovaksi murheesta muuttuneen
vain sydämen tulella hiljalleen
voi avata, herättää henkiin sen.

Olin kylmä ja vieras, tylykin.


Miten lämmetä saatoit, sisarein —?
Minä tyhjin silmin katselin.
Miten löysit kuitenkin sydämein —?

Olen kärsinyt ehkä syvemmin.


Tilin elämän kanssa selväksi tein,
Minä kuljin sydämin kivisin
kovin kauan myöskin, sisarein —»
AMETISTI

Nään yllä äänettömän ulapan yöpilven varjon sinipunaisen


kuin unen herkän, olemattoman tai unohtuneen siiven, ohuen,

Ma pelkään hiljaisuuteen hengittää —


Ah, hengityskin merta myöten pois
kuin aavelaiva voisi viilettää,
ja joku jossakin sen nähdä vois.

Ma läsnäoloasi vapisen, sa kirkkain onni, saavuttamaton.


Pian herätessä jälleen tuulien taas unet särkyy, etähällä on —
VALKEA HÄMÄRÄ

Meren suuri ja harmaa rauha


minun sieluuni selkenee.
Vesi pitkästä aaltoilusta
meren rannoilla hiljenee.

On ulappa kevyen kirkas:


Karit etäiset lähellä nään.
Kivet rannoilla selvinä piirtyy
meren valkeaan hämärään.

Olen lentänyt uupuvin siivin


meren pitkää pimeää
kuin harmaa haahkojen rivi,
jota silmä ei sumusta nää.

Nyt suuri ja harmaa rauha


yli kaiken selkenee,
ja väsynyt, levoton vesi
meren rannoilla hiljenee.
S
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