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Package Title: Testbank
Course Title: pap14
Chapter Number: 06
a) communication
b) support
c) protection
d) mineral homeostasis
e) blood cell production
Answer: a
Difficulty: Easy
Study Objective 1: SO 6.1 Describe the six main functions of the skeletal system.
Section Reference 1: Sec 6.1 Functions of Bone and the Skeletal System
a) diaphysis
b) epiphysis
c) metaphysis
d) periosteum
e) marrow
Answer: b
Difficulty: Easy
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
a) diaphysis
b) epiphysis
c) metaphysis
d) periosteum
e) marrow
Answer: a
Difficulty: Easy
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
4) Which a layer of hyaline cartilage reduces friction between bones involved in a joint?
a) periosteum
b) distal epiphysis
c) nutrient foramen
d) articular cartilage
e) epiphyseal plate
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
a) periosteum
b) distal epiphysis
c) nutrient foramen
d) articular cartilage
e) epiphyseal plate
Answer: e
Difficulty: Medium
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.2 Explain how bone grows in length and thickness.
Section Reference 1: Sec 6.2 Bone formation
6) What is the region of long bone found between the diaphysis and the epiphysis called?
a) epiphyseal plate
b) epiphyseal line
c) metaphysis
d) diaphyseal line
e) diaphyseal plate
Answer: c
Difficulty: Easy
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
7) What is the fibrous covering on the surface of bone that is involved in thickening of the bone
called?
a) periosteum
b) endosteum
c) marrow
d) epiphysis
e) metaphysis
Answer: a
Difficulty: Medium
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
8) Which of following selections lists bone cells in the order from unspecialized stem cell to
highly specialized mature bone cell?
Answer: b
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
a) fibroblasts
b) osteoclasts
c) osteocytes
d) osteoblasts
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
a) osteogenic cells
b) osteoclasts
c) osteocytes
d) osteoblasts
e) all of these choices
Answer: b
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
12) What are the extracellular fluid filled extensions of the lacunae called?
a) perforating (Volkmann’s) canals
b) central (Haversian) canals
c) osteons
d) canaliculi
e) periosteum
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
Answer: c
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.3 Compare the structural and functional differences between compact
and spongy bone tissue.
Section Reference 1: Sec 6.3 Histology of Bone Tissue
Answer: e
Difficulty: Easy
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
15) Which of the following activities has the greatest effect on bone remodeling and bone
deposition?
a) walking
b) sleeping
c) running.
d) jumping.
e) both c and d
Answer: e
Difficulty: Medium
Study Objective 1: SO 6.8 Describe how exercise and mechanical stress affect bone tissue.
Section Reference 1: Sec 6.8 Exercise and Bone Tissue.
Answer:
Difficulty: Medium
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
Solution: during bone deposition, osteogenic cells develop into osteoblasts. The osteoblasts
secrete collagen fibers and other organic substances to begin formation of matrix. Within the
spaces between fibers, calcification occurs to form a solid matrix that eventually surrounds the
osteoblast and some extracellular fluid. The osteoblast in its new lacuna is isolated and becomes
an osteocyte. The osteocyte continues to secrete matrix but at a lower level.
Answer:
Difficulty: Medium
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
Solution: during bone resorption, an osteoclast attaches tightly to the endosteum or periosteum of
the bone and forms a leak proof seal at the edges. Then it releases protein-digesting lysosomal
enzymes and several amino acids into the sealed pocket. The enzymes digest collagen fibers and
other organic substances while the acids dissolve the bone materials. Working together several
osteoclasts carve out a small tunnel in the old bone. The degraded bone proteins and extracellular
matrix minerals enter an osteoclast by endocytosis, cross the cell in vesicles, and undergo
exocytosis on the side opposite the ruffled border. Now in the interstitial fluid, the products of
bone resorption diffuse into nearby blood capillaries. Once a small area of bone has been
resorbed, osteoclasts depart and osteoblasts move in to rebuild bone in that area.
18) Which of the following two minerals are needed in large quantities when bones are growing?
Answer: c
Difficulty: Hard
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
19) Which of the following correctly lists the order of the four zones of cartilage found within
the growth plate starting at the epiphysis and extending to the diaphysis?
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
20) During adulthood, which of the following does NOT significantly contribute to bone
remodeling and growth?
a) parathyroid hormones
b) vitamin D
c) epinephrine
d) sex steroids
e) human growth hormone
Answer: c
Difficulty: Hard
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.3 Describe the process involved in bone remodeling.
Section Reference 1: Sec 6.5 Bone Formation.
21) Which type of fracture is considered a partial fracture and is only seen in children?
a) open
b) comminuted
c) impacted
d) greenstick
e) stress
Answer: d
Difficulty: Easy
Study Objective 1: SO 6.6 Describe common types of fractures and the process of fracture repair.
Study Objective 2: SO 6.6.1 Describe several common types of fractures.
Section Reference 1: Sec 6.6 Fracture and Repair of Bone.
a) rib
b) clavicle
c) humerus
d) ulna
e) tibia
Answer: e
Difficulty: Hard
Study Objective 1: SO 6.6 Describe common types of fractures and the process of fracture repair.
Study Objective 2: SO 6.6.1 Describe several common types of fractures.
Section Reference 1: Sec 6.6 Fracture and Repair of Bone.
a) calcitriol
b) calcitonin
c) human growth hormone
d) parathyroid hormone
e) insulin
Answer: d
Difficulty: Medium
Study Objective 1: SO 6.7 Describe the importance and regulation of calcium in the body.
Study Objective 2: SO 6.7.2 Explain how blood calcium level is regulated.
Section Reference 1: Sec 6.7 Bone’s Role in Calcium Homeostasis
Answer: b
Difficulty: Medium
Study Objective 1: SO 6.7 Describe the importance and regulation of calcium in the body.
Study Objective 2: SO 6.7.2 Explain how blood calcium level is regulated.
Section Reference 1: Sec 6.7 Bone’s Role in Calcium Homeostasis.
Answer:
Difficulty: Easy
Study Objective 1: SO 6.6 Describe common types of fractures and the process of fracture repair.
Study Objective 2: SO 6.6.2 Describe the sequence of events involved in fracture repair.
Section Reference 1: Sec 6.6 Fracture and Repair of Bone
Solution: after the break in the bone occurs, blood vessels in that area are damaged and blood
surrounds the fracture. The blood solidifies to form a clot, which reduces bleeding. White blood
cells migrate into the area to remove bacteria and damaged cells. Osteoclasts migrate in to
remove dead bone matrix. Secondly, fibroblasts migrate into the fracture to form a plate of
cartilage to prevent further movement and damage at the fracture site. Thirdly, osteoblasts invade
to replace the cartilage with bone matrix in the form of spongy bone. Lastly, the bone matrix will
be remodeled as compact bone replaces spongy bone.
26) Briefly describe the processes by which bone increases in length and diameter.
Answer:
Difficulty: Medium
Study Objective 1: SO 6.5 Describe the process and purpose of bone remodeling.
Study Objective 2: SO 6.5.2 Explain how bone grows in length and thickness.
Section Reference 1: Sec 6.5 Bone Formation.
Solution: The only means by which bone can increase in length (interstitial growth) is by activity
at the epiphyseal plate. Until full height is reached, the plate consists of layers of chondrocytes,
which generate matrix that is then calcified and replaced by bone matrix secreted by osteoblasts
on the diaphyseal side of the plate. Around ages 18-20 the cartilage is replaced completely by
bone and no more lengthwise growth can occur. Bone increases in diameter via appositional
growth as new bone matrix is laid down by osteoblasts in the periosteum.
27) Patient X has a tumor of the parathyroid glands that causes a hypersecretion of PTH from
these glands. Predict the effect this hypersecretion would have on the skeletal system and on the
secretion of calcitonin from the thyroid gland.
Answer:
Difficulty: Hard
Study Objective 1: SO 6.7 Describe the importance and regulation of calcium in the body.
Study Objective 2: SO 6.7.2 Explain how blood calcium level is regulated.
Section Reference 1: Sec 6.7 Bone’s Role in Calcium Homeostasis
Solution: High levels of PTH would cause high levels of osteoclast activity, thus removing
calcium from bones. Bones would become weak and soft. Excess phosphate would be lost from
the kidneys. High levels of calcium ions in blood may disrupt nerve and muscle function.
Calcitonin levels would probably be high, trying to restore homeostasis by increasing deposition
of calcium into bone.
28) An archeologist and an anthropologist are studying two skeletons from an ancient tomb that
had apparently been looted in an earlier time. Both skeletons are females and both are
approximately the same height. However, the anthropologist is absolutely certain that one
skeleton is the remains of someone from the privileged class while the other skeleton is the
remains of a servant or slave.
How could the anthropologist be so sure of the economic status of the individuals based solely
on their skeletal remains?
Answer:
Difficulty: Hard
Study Objective 1: SO 6.8 Describe how exercise and mechanical stress affect bone tissue.
Section Reference 1: Sec 6.8 Exercise and Bone Tissue.
Solution: A person who is from the privileged class probably has better nutrition but doesn’t
have to do as much physical labor (exercise) as a person from the servant or slave class. The
anthropologist probably notes a difference in bone density in the two skeletons—especially on
parts of bones where muscles attached. The skeleton of the servant probably has more density
than the skeleton of the privileged class at those points. It is also possible that the servant
suffered from malnutrition during life. If so, her skeleton might show evidence of rickets or
osteopenia.
29) Describe the signs and symptoms of osteoporosis and describe the risk factors for developing
osteoporosis.
Answer:
Difficulty: Medium
Study Objective 1: SO 6.9 Describe the effects of aging on bone tissue.
Learning Objective 1: LO 6.10 Describe the disorders that affect bone tissue.
Section Reference 1: Sec 6.9 Aging and Bone Tissue
Section Reference 1: Sec Disorders: Homeostatic Imbalances that Affect Bone Tissue
Solution: In osteoporosis, bone resorption outpaces bone deposition so that bone mass is
depleted, sometimes to the point of spontaneous fracture. Pain and height loss may occur as
vertebrae shrink. Postmenopausal women are especially at risk due to dramatically reduced
estrogen levels after menopause. Family history may play a role, as does ethnicity (white and
Asian women have a higher rate of disease), inactivity, cigarette smoking, excessive alcohol
consumption, and a diet low in calcium and vitamin D.
30) Which of the following hormones is the most important for Ca2+ regulation?
a) parathyroid hormone
b) calcitriol
c) thyroid hormone
d) calcitonin
e) aldosterone
Answer: a
Difficulty: Easy
Study Objective 1: SO 6.7 Describe the importance and regulation of calcium in the body.
Section Reference: 1: 6.7 Bone’s Role in Calcium Homeostasis
31) In which region of the diagram would you find the medullary cavity?
a) A
b) B
c) C
d) D
e) E
Answer: c
Difficulty: Medium
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
32) Where in the diagram can you find red bone marrow in an adult?
a) D
b) A and B
c) A and C
d) C
e) E
Answer: b
Difficulty: Medium
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
33) Where in the diagram is the metaphysis?
a) A
b) B
c) C
d) D
e) E
Answer: b
Difficulty: Easy
Learning Objective 1: 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
34) What structure in the diagram is the only place on a long bone NOT covered by the
periosteum?
a) A
b) B
c) C
d) D
e) E
Answer: e
Difficulty: Easy
Study Objective 1: SO 6.2 Describe the structure and functions of each part of a long bone.
Section Reference 1: Sec 6.2 Structure of Bone
35) What type of bone cell starts forming the bone matrix?
a) A
b) B
c) C
d) D
Answer: b
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
a) A
b) B
c) C
d) D
Answer: d
Difficulty: Easy
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
37) Which bone cell in the diagram below is a mature bone cell that helps maintain bone tissue?
a) A
b) B
c) C
d) D
Answer: c
Difficulty: Easy
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
a) A
b) B
c) C
d) D
Answer: a
Difficulty: Easy
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.2 Describe the cellular composition of bone tissue and the functions
of each type of cell.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
a) C
b) A
c) E
d) F
e) D
Answer: c
Difficulty: Medium
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.3 Compare the structural and functional differences between compact
and spongy bone tissue.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
40) In the diagram, where is the osteon?
a) A
b) B
c) C
d) D
e) E
Answer: c
Difficulty: Easy
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.3 Compare the structural and functional differences between compact
and spongy bone tissue.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
41) In the diagram, where is the trabeculae?
a) B
b) C
c) D
d) E
e) F
Answer: a
Difficulty: Easy
Study Objective 1: SO 6.3 Compare the properties of compact and spongy bone tissue.
Study Objective 2: SO 6.3.3 Compare the structural and functional differences between compact
and spongy bone tissue.
Section Reference 1: Sec 6.3 Histology of Bone Tissue.
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and ‘quight’ as advb., ‘And cover them (i.e. the lands) quite.’ The
second explanation involves a difficult parenthesis of ‘And fire
deuoure the ayre’: ‘hell’ does not occur elsewhere in F. Q. as a verb,
even in the form ‘hele’, though ‘vnhele’ = uncover is found in II. xii.
64 l. 8; hence it has been proposed to read ‘mell’ = confuse. But the
first line of interpretation seems the more satisfactory.
IV. xi. 4 l. 6. seuen] three Malone 616 and G. 11557 in B. M. All other
copies of 1596 ‘seuen’. This is another instance of correction at
press. See above on IV. x. 23. 1609 reads ‘three’. I cannot say which
reading represents the poet’s second thought.
IV. xi. 17 l. 6. times] age Todd. But see Introduction, p. viii.
IV. xi. 34 l. 5. Grant] Guant 1596, 1609: corr. Child. ‘Grant’ is for
Granta, i.e. the Cam, as Upton noted.
IV. xi. 52 l. 7. but] both conj. edd. The text is sound. Floods and
fountains, though originally all derived from ocean, are yet akin to
sky and sun.
IV. xii. 13 ll. 1, 2. For the significance of these variants see
Introduction, p. xix.
IV. xii. 23 l. 9. That no old sore it was 16(11)-12-13.
V. Proem 2 l. 2. at earst] as earst 16(11)-12-13. But cf. S. C. Dec.
105, where there is the same contrast between ‘first’ and ‘at earst’.
Also F. Q. VI. iii. 8 l. 7; 39 l. 1.
V. Proem 2 l. 9. degendered] degenerd 16(11)-12-13.
V. Proem 7 l. 8. thirtie] thirteen conj. Child. Child’s ‘thirteen’ is said to
be astronomically correct, or nearly so, for Spenser’s date.
V. Proem 9 l. 4. ne], no 16(11)-12-13.
V. Proem 11 l. 2. stead] place 1596. On this substitution see
Introduction, p. viii. This is the only correction of this nature in 1609,
and I have accepted it for reasons given in Introduction, p. xix.
V. ii. Arg. 3. Munera] Momera 1596, 1609: corr. Hughes. As a rule I
do not accept such corrections in proper names. But this is a
printer’s not an author’s error.
V. ii. 11 l. 4. Who] Tho conj. Church: When Morris. But such changes
of construction are not uncommon when a clause intervenes as
here.
V. ii. 46 l. 9. way] lay 1609. But identical rhymes, especially of
homonyms, are not uncommon in this part of the stanza. See,
however, note on III. xi. 47 l. 9.
V. iii. 11 ll. 7, 9. Th’other ... th’other 1596, 1609. Erroneous
apostrophation occurs again at V. vi. 19 l. 3. Cf. also note on V. v. 18
l. 4.
V. iii. 19 l. 1. the azure] th’azure 1609. See note on I. i. 15 l. 6.
V. iv. 1 l. 3. Had neede haue] Had neede of 16(11)-12-13.
V. iv. 22 l. 2. pinnoed] pinniond 16(11)-12-13.
V. iv. 36 l. 8. Ere long their Queene her selfe, halfe like a man] selfe
halfe, 1596: self, arm’d 1609. 1609 may be right; ‘halfe’ in 1596 may
have been repeated by parablepsy from ‘selfe’: the punctuation of
1596 points to that.
V. iv. 37 l. 1. neare] newe conj. Church. 3 so few] to feare conj.
Collier. Imperfect rhymes are not rare in F. Q., but scarcely in this
form; here there is no assonance. Nor does this seem to be one of
the ‘substitutions’ discussed in Introduction, p. viii. Of conjectures,
Church’s is the best.
V. iv. 37 l. 6. there] their 16(11)-12-13.
V. iv. 39 l. 3. So cruell doale amongst her maides diuide] ... doile ...
dauide 1596. There are two words ‘dole’ in Spenser, (a) portion, (b)
mourning. This is (a): for the phrase cf. Shakespeare, 2 Hen. IV, 1. i.
169, ‘That in the dole of blows your son might drop.’ Spenser does
not elsewhere use ‘dole’ in sense (a); in sense (b) it is common in F.
Q., and is spelt ‘dole’ or ‘doole’. The spelling ‘doile’ (Fr. deuil)
belonged rather to sense (b), but no sixteenth century instance is
quoted in N. E. D. It is not impossible that Spenser wrote ‘doile’ in
sense (a), intending a play upon the two meanings. But more
probably ‘a’ and ‘i’ have simply been interchanged, as 1609 takes it.
(1596 generally has ‘deuide’; but ‘diuide’ also occurs.)
V. iv. 48 l. 7. yesterday] yeester day 1596. Morris keeps ‘yeester’; but
Spenser has ‘yester’ elsewhere, and a misprint is probable. The
latter part of this canto, as these notes show, is unusually full of such
difficulties.
V. v. 18 l. 4. to’a] The apostrophation shows synezesis, though the
vowel is not omitted.
V. v. 38 l. 8. And, though (vnlike)] And, though vnlike 1596. The
meaning is, ‘And even if (as is unlikely) they should last, &c.’
V. vi. 5 ll. 6, 7.
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