Professional Documents
Culture Documents
Pharmacology
Pharmacology
Pharmacology
1. Acetaminophen
Class: Analgesics (pain relievers) and Antipyretics (fever reducer)
Temporary relief of mild to moderate pain, headache, and fever.
Mechanism of Action:
o Analgesic: Activates descending serotonergic inhibitory pathways in CNS.
o Antipyretic: Inhibits hypothalamic heat- regulating center.
Therapeutic Effect: Results in antipyresis. Produces analgesic effect.
Nursing Considerations:
o Assess onset, type, location, duration of pain.
o Assess for Fever.
o Assess LFT (liver function tests) in pts with chronic usage or history of hepatic impairment, alcohol abuse.
o Do not exceed maximum daily recommendation dose: 4g/day.
Side Effects:
o Hypersensitivity Reaction.
Adverse Effects of Acetaminophen Toxicity:
o Anorexia, Nausea, Diaphoresis, Fatigue within first 12-24 hours.
o Vomiting, RUQ tenderness, elevated LFTs within 48-72 hours.
Patient Teachings:
o Avoid alcohol.
o Do not take more than 4g/day.
o Severe recurrent pain, or fever may indicate serious illness.
2. Acetylsalicylic Acid (Aspirin)
Class: NSAIDs
Treatment of mild to moderate pain, fever.
Reduces inflammation related to arthritis.
Used in the prevention of TIAs, cerebral thromboembolism, MI or reinfarction.
Mechanism of Action:
o Irreversibly inhibits cyclo-oxygenase enzyme, resulting in a decreased formation of prostaglandin precursors.
o Irreversibly inhibits formation of thromboxane, resulting in inhibiting platelet aggregation.
Therapeutic Effect: Reduces inflammatory response, intensity of pain; decreases fever; inhibits platelet aggregation.
Nursing Considerations:
o Do not give to children or teenagers who have or have recently had viral infections.
o Assess history of GI bleed, peptic ulcer disease, OTC use of products that may contain aspirin.
o Inspect appearance of affected joints for immobility, deformities, skin condition.
o Monitor urinary pH (pH from 6.5 to 5.5, may result in toxicity).
Side Effects:
o GI distress and allergic reaction.
Adverse Effects:
o Reye’s syndrome.
Patient Teachings:
o Do not chew, crush, dissolve or divide enteric-coated tablets.
o Avoid alcohol.
3. Amiodarone
Class: Antiarrhythmics
Management of life-threatening recurrent ventricular fibrillation, (VF), or recurrent hemodynamically unstable
ventricular tachycardia (VT).
Treatment of atrial fibrillation, paroxysmal supraventricular tachycardia (SVT) and ventricular tachyarrhythmias.
Mechanism of Action:
o Inhibits adrenergic stimulation; affects Na, K, Ca channels; prolongs action potential and refractory period in
myocardial tissue. Decreases AV conduction and sinus node function.
Therapeutic Effect: Suppresses arrhythmias.
Nursing Considerations:
o Obtain BP, apical pulse. (Withhold if pulse is less than 60bpm, or systolic BP is less than 90mmHg).
o Obtain baseline serum ALT, AST, alkaline phosphatase, ECG.
o Monitor for symptoms of pulmonary toxicity.
Side Effects:
o Expected: Corneal microdeposits.
o Occasional: Constipation, headache, decreased appetite, nausea, vomiting, paresthesia, photosensitivity,
muscular incoordination, hypotension, nausea, fever, bradycardia.
o Rare: Bitter or metallic taste, decreased libido, dizziness, facial flushing, blue-gray coloring of skin (face, arms,
and neck), blurred vision, bradycardia, asymptomatic corneal deposits, rash, visual disturbances, halo vision.
Adverse Effects:
o Pulmonary Toxicity:
May begin with progressive dyspnea and cough with crackles.
Patient Teachings:
o Protect against photosensitivity reaction.
o Restrict salt, alcohol intake.
o Avoid grapefruit products.
4. Amlodipine
Class: Calcium Channel Blockers
Management of hypertension, coronary artery disease (chronic stable angina, vasospastic [Prinzmetal’s or variant]
angina).
Mechanism of Action:
o Inhibits calcium movement across cardiac and vascular smooth muscle cell membranes during depolarization.
Therapeutic Effect: Dilates coronary arteries, peripheral arteries/arterioles. Decreases total peripheral vascular
resistance and B/P by vasodilation.
Nursing Consideration:
o Assess baseline renal/hepatic function tests, B/P, apical pulse.
o Assess B/P (if systolic B/P is less than 90 mm Hg, withhold medication, contact physician).
o Assess for peripheral edema behind medial malleolus.
Side Effects:
o Frequent: Peripheral edema, headache, flushing.
o Occasional: Dizziness, palpitations, nausea, unusual fatigue or weakness.
o Rare: Chest pain, bradycardia, orthostatic hypotension.
Adverse Effects:
o Overdose may produce excessive peripheral vasodilation, marked hypotension with reflex tachycardia, syncope.
Patient Teachings:
o Do not ingest grapefruit products.
5. Atorvastatin (Lipitor)
Class: HMB – CoA Reductase Inhibitor *statin*
Primary prevention of cardiovascular disease in high-risk pts.
Reduces risk of stroke and heart attack.
Mechanism of Action:
o Inhibits HMG-CoA reductase, the enzyme that catalyzes the early step in cholesterol synthesis. Results in an
increase of expression in LDL receptors on hepatocyte membranes and a stimulation of LDL catabolism.
Therapeutic Effect: Therapeutic Effect: Dilates coronary arteries, peripheral arteries/arterioles. Decreases total
peripheral vascular resistance and B/P by vasodilation.
Nursing Considerations:
o Obtain baseline cholesterol, triglycerides, LFT.
o Monitor for headache.
o Assess for rash, pruritus, malaise.
o Monitor cholesterol, triglyceride lab values for therapeutic response.
Side Effects:
o Frequent: Headache.
o Occasional: Myalgia, rash, pruritus, allergy.
o Rare: Flatulence, dyspepsia, depression.
Adverse Effects:
o Potential for cataracts, photosensitivity, myalgia, rhabdomyolysis.
Patient Teachings:
o Follow special diet.
o Do not chew, crush, dissolve, or divide tablets.
o Report dark urine, muscle fatigue, and bone pain.
o Avoid alcohol and large quantities of grapefruit products.
6. Apixaban
Class: Anticoagulant.
Reduces risk for stroke, systemic embolism in pts with nonvalvular atrial fibrillation.
Treatment of DVT and PE.
Mechanism of Action:
o Selectively, directly, and reversibly inhibits free and clot-bound factor Xa, a key factor in the intrinsic and
extrinsic pathway of blood coagulation cascade.
Therapeutic Effect: Therapeutic Effect: Dilates coronary arteries, peripheral arteries/arterioles. Decreases total
peripheral vascular resistance and B/P by vasodilation.
Nursing Considerations:
o Obtain baseline CBC, stool for occult blood.
o Obtain health history.
o Assess for any sign of bleeding.
Side Effects:
o Rare: Nausea, ecchymosis.
Adverse Effects:
o Increased risk for bleeding/hemorrhagic events.
Patient Teachings:
o Avoid alcohol.
o Avoid aspirin, NSAIDs, herbal supplements.
o Avoid grapefruit products.
7. Bisoprolol
Class: Beta1 Selective Adrenergic Blocker (Antihypertensive)
Management of hypertension.
Mechanism of Action: Selectively blocks beta1-adrenergic receptors.
Therapeutic Effect: Slows sinus heart rate, decreases B/P.
Nursing Considerations:
o Obtain B/P, apical pulse. (Withhold if pulse is less than 60bpm, or systolic BP is less than 90mmHg).
o Assist with ambulation if dizziness occurs.
o Assess for peripheral edema.
o Monitor daily pattern of bowel activity, stool consistency.
o Assess neurologic status.
Side Effects:
o Frequent: Fatigue, headache.
o Occasional: Dizziness, arthralgia, peripheral edema, URI, rhinitis, pharyngitis, diarrhea, nausea, insomnia.
o Rare: Chest pain, asthenia, dyspnea, vomiting, bradycardia, dry mouth, diaphoresis, decreased libido,
impotence.
Adverse Effects:
o Overdose may produce bradycardia and hypotension.
o Abrupt withdrawal may result in diaphoresis, palpitations, headache, tremors.
Patient Teachings:
o Do not use nasal decongestants, OTC cold preparations (stimulants) without physician’s approval.
o Restrict salt, alcohol intake.
8. Candesartan
Class: Angiotensin II Receptor Blockers (ARB) (Antihypertensive)
Treatment of hypertension.
Mechanism of Action: Blocks vasoconstriction, aldosterone-secreting effects of angiotensin II, inhibiting binding of
angiotensin II to AT receptors.
Therapeutic Effect: Produces vasodilation; decreases peripheral resistance, B/P.
Nursing Considerations:
o Obtain B/P, apical pulse immediately before.
o Obtain health history.
o Maintain hydration.
o Assess for upper respiratory infection.
Side Effects:
o Occasional: Upper respiratory tract infection, dizziness, back/leg pain.
o Rare: Pharyngitis, rhinitis, headache, fatigue, diarrhea, nausea, dry cough, peripheral edema.
Adverse Effects:
o Overdosage may manifest as hypotension, tachycardia.
o Bradycardia occurs less often.
o May increase risk of renal failure, hyperkalemia.
Patient Teachings:
o Inform female pts regarding potential for fetal injury, mortality with second- and third- trimester exposure to
candesartan.
o Avoid task that require alertness.
9. Clopidogrel
Class: Antiplatelet
To reduce rate of MI and stroke.
Mechanism of Action: Active metabolite irreversibly blocks P2Y12 component of ADP receptors on platelet surface,
preventing activation of GPIIb/IIIa receptor complex.
Therapeutic Effect: Inhibits platelet aggregation.
Nursing Considerations:
o Perform platelet counts before drug therapy.
o Obtain baseline chemistries, platelet count, PFA.
Side Effects:
o Frequent: Skin disorders.
o Occasional: Upper respiratory tract infection, chest pain, flu-like symptoms, headache, dizziness, arthralgia.
o Rare: Fatigue, edema, hypertension, abdominal pain, dyspepsia, diarrhea, nausea, epistaxis, dyspnea, rhinitis.
Adverse Effects:
o Agranulocytosis, aplastic anemia/pancytopenia, thrombotic thrombocytopenic purpura (TTP).
Patient Teachings:
o It may take longer to stop bleeding during drug therapy.
o Report any unusual bleeding.
10. Dalteparin
Class: Anticoagulant
A blood thinner indicated to prevent ischemic complication in unstable angina and non-Q-wave myocardial infarction.
Used for the prevention of deep vein thrombosis.
Mechanism of Action: Antithrombin in presence of low molecular weight heparin inhibits factor Xa, thrombin. Only
slightly influences platelet aggregation, PT, aPTT.
Therapeutic Effect: Produces anticoagulation.
Nursing Considerations:
o Obtain baseline coagulation studies, CBC, esp. platelet count.
o Periodically monitor CBC, stool for occult blood.
o Assess for any sign of bleeding.
o Monitor for DVT.
Side Effects:
o Occasional: Hematoma at injection site.
o Rare: Hyper-sensitivity reaction (chills, fever, pruritus, urticaria, asthma, rhinitis, lacrimation, headache); mild,
local skin irritation.
Adverse Effects:
o Overdose may lead to bleeding complications ranging from local ecchymoses to major hemorrhage.
Patient Teachings:
o Usual length of therapy is 5–10 days.
o Do not take any OTC medication (esp. aspirin) without consulting physician.
o Rotate injection sites daily.
o Teach proper injection technique.
o Excessive bruising at injection site may be lessened by ice massage before injection.
o Monitor for symptoms of blood clots in the leg or blood clots in the lungs.
11. Diclofenac
Class: NSAIDs
Treatment of arteritis and mild-to-moderate pain.
Mechanism of Action: Reversibly inhibits cyclo-oxygenase-1 and -2 (COX-1 and COX-2) enzymes, resulting in
decreased formation of prostaglandin precursors.
Therapeutic Effect: Produces analgesic, antipyretic, anti-inflammatory effects.
Nursing Considerations:
o Obtain baseline B/P.
o Monitor CBC, renal function, LFT, urine output, occult blood test, B/P.
Side Effects:
o Frequent: Headache, abdominal cramps, constipation, diarrhea, nausea, dyspepsia. Ophthalmic: Burning,
stinging on instillation, ocular discomfort.
o Occasional: PO: Flatulence, dizziness, epigastric pain. Ophthalmic: Ocular itching, tearing.
o Rare: PO: Rash, peripheral edema, fluid retention, visual disturbances, vomiting, drowsiness.
Adverse Effects:
o Overdose may result in acute renal failure.
Patient Teachings:
o Swallow tablets whole; do not chew, crush, dissolve, or divide.
o Avoid aspirin, alcohol during therapy (increases risk of GI bleeding).
o If GI upset occurs, take with food, milk.
o Ophthalmic: Do not use hydrogel soft contact lenses.
12. Diltiazem
Class: Calcium Channel Blocker.
Treatment of angina and hypertension.
Mechanism of Action: Inhibits calcium movement across cardiac, vascular smooth-muscle cell membranes (causes
dilation of coronary arteries, peripheral arteries, arterioles) during depolarization.
Therapeutic Effect: Relaxes coronary vascular smooth muscle, and coronary vasodilation increases myocardial oxygen
delivery in pts with vasospastic angina.
Nursing Consideration:
o Assess B/P, apical pulse immediately before drug is administered.
o Obtain baseline ECG in pts with history of arrhythmia.
o Assist with ambulation if dizziness occurs.
o Assess for peripheral edema.
Side Effects:
o Frequent: Peripheral edema, dizziness, light-headedness, headache, bradycardia, asthenia.
o Occasional: Nausea, constipation, flushing, ECG changes.
o Rare: Rash, micturition disorder (polyuria, nocturia, dysuria, frequency of urination), abdominal discomfort,
drowsiness.
Adverse Effects:
o Overdose produces nausea, drowsiness, confusion, slurred speech, profound bradycardia.
Patient Teachings:
o Avoid alcohol (may increase risk of hypotension or vasodilation).
13. Digoxin
Class: Antiarrhythmic
Treatment of mild to moderate HF, can also treat atrial fibrillation.
Mechanism of Action:
o HF: Inhibits sodium/potassium ATPase pump in myocardial cells. Promotes calcium influx.
o Supraventricular arrhythmias: Suppresses AV node conduction.
Therapeutic Effect:
o HF: Increases contractility.
o Supraventricular arrhythmias: Increases effective refractory period/decreases conduction velocity, decreases
ventricular heart rate of fast atrial arrhythmias.
Nursing Consideration:
o Assess apical pulse (if pulse is 60 or less/min (70 or less/min for children), withhold drug, contact physician).
o Monitor pulse for bradycardia, ECG for arrhythmias for 1–2 hrs after administration.
Side Effects:
o Dizziness, headache, diarrhea, rash, visual disturbances.
Adverse Effects:
o GI disturbances, neurologic abnormalities, facial pain, personality change, ocular disturbances.
Patient Teachings:
o Wear/carry identification of digoxin therapy and inform dentist, other physician of taking digoxin.
14. Fondaparinux
Class: Factor Xa Inhibitors (Anticoagulant)
Prevention of venous thromboembolism.
Treatment of acute deep vein thrombosis (DVT) and acute pulmonary embolism.
Mechanism of Action:
o Factor Xa inhibitor that selectively binds to antithrombin and increases its affinity for factor Xa, inhibiting
factor Xa, stopping blood coagulation cascade.
Therapeutic Effect:
o Indirectly prevents formation of thrombin and subsequently fibrin clot.
Nursing Considerations:
o Assess CBC, renal function test.
o Evaluate potential risk for bleeding.
o Obtain health history.
o Monitory BP and pulse.
Side Effects:
o Frequent: Anemia, fever, nausea.
o Occasional: Edema, constipation, rash, vomiting, insomnia, increased wound drainage, hypokalemia.
o Rare: Dizziness, hypotension, confusion, urinary retention, injection site hematoma, diarrhea, dyspepsia,
headache.
Adverse Effects:
o Bleeding complications.
Patient Teachings:
o Do not take OTC medications.
o Report swelling or unusual bleedings.
15. Furosemide
Class: Diuretics
Treatment of edema associated with HP and renal/hepatic disease; acute pulmonary edema.
Treatment of hypertension.
Mechanism of Action:
o Inhibits reabsorption of sodium, chloride in ascending loop of Henle and proximal/distal renal tubules.
Therapeutic Effect:
o Increases excretion of water, sodium, chloride, magnesium, calcium.
Nursing Considerations:
o Check BP, pulse for hypotension before administration.
o Assess baseline renal functions.
o Assess hydration status.
o Obtain baseline weight.
o Initiate I&O.
Side Effects:
o Expected: Increased urinary frequency/volume.
o Frequent: Nausea, dyspepsia, abdominal cramps, diarrhea or constipation, electrolyte disturbances.
o Occasional: Dizziness, light-headedness, headache, blurred vision, paresthesia, photosensitivity, rash, fatigue,
bladder spasm, restlessness, diaphoresis.
o Rare: Flank pain.
Adverse Effects:
o Profound water loss/electrolyte depletion, resulting in hypokalemia, hyponatremia, dehydration.
o Increased risk of thrombosis, circulatory collapse, and sudden death.
Patient Teachings:
o Increased urination.
o Eat foods high in potassium.
o Avoid sunlight, sunlamps.
16. Gabapentin
Class: Anticonvulsant
Used to prevent and control partial seizures and relieve nerve pain following shingles.
Mechanism of Action:
o Binds to gabapentin binding sites in brain and may modulate release of excitatory neurotransmitters, which
participates in epileptogenesis and nociception.
Therapeutic Effect:
o Reduces seizure activity, neuropathic pain.
Nursing Considerations:
o Obtain health history.
o Provide safety measures.
o Monitor for signs of depression or unusual behaviour.
Side Effects:
o Frequent: Fatigue, drowsiness, dizziness, ataxia.
o Occasional: Nystagmus, tremor, diplopia, rhinitis, weight gain, peripheral edema.
o Rare: Anxiety, dysarthria, memory loss, dyspepsia, pharyngitis, myalgia.
Adverse Effects:
o Abrupt withdrawal may increase seizure activity.
o Hypersensitivity reactions.
Patient Teachings:
o Avoid tasks that require coordination.
o Avoid alcohol.
o Wear medical ID band.
17. Gliclazide
Class: Sulfonylurea
Used to control high blood sugar in people with Type 2 Diabetes.
Mechanism of Action:
o Gliclazide binds to the β cell sulfonyl urea receptor (SUR1). This binding subsequently blocks the ATP sensitive
potassium channels. The binding results in closure of the channels and leads to a resulting decrease in potassium
efflux leads to depolarization of the β cells. This opens voltage-dependent calcium channels in the β cell
resulting in calmodulin activation, which in turn leads to exocytosis of insulin containing secretorty granules.
Therapeutic Effect:
o Increases the amount of insulin released by the pancreas and helps the body use insulin more effectively.
Nursing Considerations:
o Monitor liver and renal functions.
o Observe for signs and symptoms of hypoglycemia.
o PO: Administer with meals at the same time every day.
Side Effects:
o Frequent: Stomach-ache, Nausea, Vomiting. Diarrhea, Constipation.
Adverse Effects:
o Yellow eyes or skin.
o Paler than usual, prolonged bleeding and bruising.
Patient Teachings:
o Proper technique for monitoring.
o Encourage prescribed diet and exercise.
o Avoid sun exposure.
18. Heparin
Class: Anticoagulant
Used to decrease the clotting ability of the blood and help prevent harmful clots from forming in blood vessels.
Prophylaxis and treatment of thromboembolic disorders and thromboembolic complications.
Mechanism of Action:
o Potentiates action of antithrombin III. Interferes with blood coagulation by blocking conversion of prothrombin
to thrombin and fibrinogen to fibrin.
Therapeutic Effect:
o Prevents further extension of existing thrombi or new clot formation. No effect on existing clots.
Nursing Considerations:
o Cross-check dose with co-worker.
o Obtain CBC, PT/INR.
o Obtain health history.
Side Effects:
o Occasional: Pruritus, burning (particularly on soles of feet) caused by vasospastic reaction.
o Rare: Pain, cyanosis of extremity 6–10 days after initial therapy lasting 4–6 hrs, hypersensitivity reaction
(chills, fever, pruritus, urticaria, asthma, rhinitis, lacrimation, headache).
Adverse Effects:
o Bleeding complications or life-threatening thromboembolism.
Patient Teachings:
o Use electric razor, soft toothbrush to prevent bleeding.
o Report red or dark urine, black or red stool, coffee-ground vomitus, blood-tinged mucus from cough, signs of
stroke, nosebleeds, or increase in menstruation.
o Do not use any OTC medication without physician approval (may interfere with platelet aggregation).
o Wear or carry identification that notes anticoagulant therapy.
o Inform dentist, other physicians of heparin therapy.
o Limit alcohol.
19. Lisinopril
Class: Angiotensin Converting Enzyme (ACE) Inhibitor
Treatment of hypertension and acute MI.
Mechanism of Action:
o Competitive inhibitor of angiotensin- converting enzyme (ACE) (prevents conversion of angiotensin I to angio-
tensin II, a potent vasoconstrictor; may inhibit angiotensin II at local vascular, renal sites). Decreases plasma
angio-tensin II, increases plasma renin activity, decreases aldosterone secretion.
Therapeutic Effect:
o Reduces blood pressure.
Nursing Considerations:
o Obtain BP, apical pulse before dose.
o Auscultate lungs.
o Weigh daily.
Side Effects:
o Frequent: Headache, dizziness, postural hypotension.
o Occasional: Chest discomfort, fatigue, rash, abdominal pain, nausea, diarrhea, upper respiratory infection.
o Rare: Palpitations, tachycardia, peripheral edema, insomnia, paresthesia, confusion, constipation, dry mouth,
muscle cramps.
Adverse Effects:
o Excessive hypotension.
o Angioedema, hyperkalemia occurs rarely.
Patient Teachings:
o Limit alcohol.
o Limit salt intake.
o Maintain hydration.
20. Losartan
Class: Angiotensin II Receptor Blocker (ARB)
Treatment of hypertension and diabetic nephropathy.
Causes blood vessels to tighten.
Mechanism of Action:
o Blocks vasoconstrictor, aldosterone- secreting effects of angiotensin II, inhibiting binding of angiotensin II to
AT1 receptors.
Therapeutic Effect:
o Causes vasodilation, decreases peripheral resistance, decreases B/P.
Nursing Considerations:
o Obtain BP, apical pulse prior.
o Maintain hydration.
o Assess for evidence of upper respiratory infection, cough.
o Assist with ambulation.
Side Effects:
o Frequent: Upper respiratory tract infection.
o Occasional: Dizziness, diarrhea, cough.
o Rare: Insomnia, dyspepsia, heartburn, back/ leg pain, muscle cramps, myalgia, nasal congestion, sinusitis,
depression.
Adverse Effects:
o Overdosage may manifest as hypotension and tachycardia. Bradycardia occurs less often.
Patient Teachings:
o Avoid pregnancy/ report pregnancy ASAP.
o Report signs of infection.
o Avoid tasks that require alertness.
o Limit salt intake.
o Do not take OTC medications.
21. Metoprolol
Class: Beta Blockers
Treatment of acute myocardial infarction, and acute angina.
Management of hypertension.
22. Morphine
Class: Opioid Analgesic
Used in pain management.
23. Metformin
Class: Biguanide Antihyperglycemic
Used to treat high blood sugar levels that are caused by diabetes (type 2).
24. Metolazone
Class: Diuretics
Treat fluid retention (edema) and swelling that is caused by congestive heart failure, kidney disease, and other medical
condition.
Treats hypertension.
25. Nitrates
Class: Nitrates
Prevent chest pain (angina), relieve the pain of a current attack, or treat the symptoms of heart failure.
26. Perindopril
Class: Angiotensin Converting Enzyme (ACE) Inhibitor
Treats hypertension and heart failure.
27. Pantoprazole
Class: Proton Pump Inhibitor
Treatment of healing erosive esophagitis associated with gastroesophageal reflux disease (GERD).
Reduction of relapse rate of heartburn.
28. Polyethylene Glycol
Class: Osmotic Laxatives
Used in the management and treatment of constipation.
29. Ramipril
Class: Angiotensin Converting Enzyme (ACE) Inhibitor
Treats hypertension and failure.
30. Rosuvastatin
Class: HMB-CoA Reductase Inhibitor
Lowers bad cholesterol (LDL) and triglycerides (fats) in the blood, and to increase your good cholesterol (HDL)
31. Risedronate
Class: Bisphosphonates
Treatment of Paget’s disease of the bone.
Prevent and treats osteoporosis (thinning of the bone) in women after menopause.
32. Rivaroxaban
Class: Anticoagulants
Prophylaxis of deep vein thrombosis (DVT).
Prevents pulmonary embolism (PE).
33. Spironolactone
Class: Aldosterone Antagonist
Treats hypertension and heart failure.
Management of edema.
34. Simvastatin
Class: HMB-CoA Reductase Inhibitor
Treats high cholesterol and triglyceride (fat) levels in the blood.
35. Salmeterol
Class: Long-acting Beta2-Adrenergic
Medication used in the management and treatment of asthma and COPD.
36. Terazosin
Class: Alpha Blockers
Lowers blood pressure.
Also treats the enlargement of the prostate (benign prostatic hyperplasia)/
37. Telmisartan
Class: Angiotensin II Receptor Blocker (ARB)
Treats hypertension.
38. Ticagrelor
Class: Antiplatelet
Prevents a serious or life-threatening heart attack or stroke, or death in people who have had a heart attack or stroke, or
who have acute coronary syndrome.
39. Tiotropium Bromide
Class: Anticholinergics
Treats chronic obstructive pulmonary disease (COPD).
40. Tinzaparin
Class: Anticoagulant
Treats serious blood clots, usually in the legs or the lungs.
41. Valsartan
Class: Angiotensin II Receptor Blocker (ARB)
Treats hypertension.