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Screenshot 2024-04-04 at 11.08.35 PM
Screenshot 2024-04-04 at 11.08.35 PM
Dr BASSEY, A E
ORTHOPAEDICS & TRAUMA
UATH, ABUJA
OUTLINE
• Introduction
• Types of bone healing
• Stages of bone healing
• Regulation of bone healing
• Factors affecting bone healing
• Assessment
• Complications
• Current trends
• Conclusion
Introduction
• Bone healing refers to complex and sequential
events that occur to restore injured bone to pre-
injury state
• Radiological
Complications
• Malunion
• Delayed union
• Non-union
• Infection
• Post-traumatic arthritis
• Growth abnormalities
Current trends
• rBMP
– Delivered locally at 10-1000x natural expression
– Enhance # healing
– Decrease infection in GA IIIa & b #s
– Useful in recalcitrant non-unions
• Pulsed electromagnetic field (PEMF)
– Used in treatment of nonunions
• Low-intensity pulsed ultrasound (LIPUS)
– Increases gene expression, enhances blood flow,
enhances remodelling
– Reverses anti-angiogenic effect of nicotine
Conclusion
• Despite major advancement in understanding
of bone healing, problems/complications still
continue to arise.