Pharmaceutics MCQs_27442249_2024_05_13_23_28

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1. Which one is not the mechanism of size separation?


(a) Agitation
(b) Brushing
(c) Centrifugation
(d) Compression

2. The ........... Samhita includes reference to drugs of animals, plants and mineral
origin used until the first century AD
(a) Ebers
(b) Charaka
(c) Hippocrates
(d) Shushruta

3. Cyclone separator works on the principle of


(a) Centrifugation
(b) Agitation
(c) Vibration
(d) Gyration

4. The efficiency of a ball mill is maximum at


(a) high speed
(b) low speed
(c) 2/3rd of speed
(d) very high speed

5. Which mill depends on the principle of combined impact and attrition


(a) ball mill
(b) hammer mill
(c) roller mill
(d) disintegrator mill

6. Size reduction is also known as


(a) communition
(b) diminution
(c) Pulverization
(d) all of the above

7. Reduction in particle size


(a) increases surface area
(b) decreases surface area
(c) decreases rate of absorption
(d) decrease in site of action for solvent

8. Hammer mill works on the principle of


(a) Impact
(b) Attrition
(c) Compression

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(d) Cutting

9. Fluidized bed dryer has an advantage of


(a) Attrition is not observed
(b) Entire material is continuously exposed to heat source
(c) Fluffy mass is formed
(d) Humidity can be increased

10. Which one of the following dryer is also known as Lyophiliser?


(a) Fluidised bed dryer
(b) Freeze dryer
(c) Spray dryer
(d) Vaccum dryer

11. How the liquid gets separated in freeze dryer?


(a) Boiling
(b) Distillation
(c) Freezing and crystallization
(d) Evaporation

12. Silverson mixer is used for the preparation of


(a) Elixir
(b) Emulsion
(c) Mouth wash
(d) Syrup

13. Filter aids are mainly used when


(a) Liquid is required as product
(b) Filter medium is not available
(c) Solid and liquid are required as products
(d) Solids are required as product

14. Which one of the following is not a mechanism of filtration?


(a) Entanglement
(b) Impact
(c) Impingement
(d) Straining

15. The efficiency of filtration increases if


(a) Compressibility of solids is high
(b) Filter aid is added to the slurry
(c) Filter medium is used
(d) Size distribution of solids is wide in slurry

16.Which one of the following is not an example of filter aid?


(a) Activated charcoal
(b) Bentonite

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(c) Kaolin
(d) Talc

17.The slurry is
(a) A suspension to be filtered
(b) A porous membrane used to retain the solids.
(c) A clear solution
(d) None of the above

18.What do you mean by filter cake?


(a) The cake which is to be filtered
(b) A porous membrane used to retain the solids
(c) The solids which are present on the filter
(d) A suspension to be filtered

19. Which of the following process is used to separate insoluble particles from
liquids?
(a) Filtration
(b) Extraction
(c) Drying
(d) Sieving

20. Which of the following does not influence filtration?


(a) Temperature
(b) Density
(c) Viscosity
(d) pH

21. Size classification is also known in one of the following terms


(a) Size analysis
(b) Size distribution
(c) Size reduction
(d) Size separation

22. Size separation is not based on


(a) Particle density
(b) Particle Shape
(c) Particle size
(d) Particle texture

23. Which one of the following indicates the nominal size of aperture
(a) Area of mesh as percentage
(b) Distance between two adjacent wires
(c) Number of meshes per linear length
(d) Wire having specified diameter that suitable aperture

24. During size separation, the movement of particles can be enhanced by


(a) Agitation

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(b) Attrition
(c) Gravitation
(d) Mixing

25. Who is the father of medicine?


(a) Ebers
(b) Hippocrates
(c) Egyptian
(d) Pontus

26. Use of formulations made up of various constituents of a plant is referred as


(a) Galenicals
(b) Parenteral
(c) Plant Vehicles
(d) Generics

27. The first pharmacy shop was opened in


(a) London
(b) Bagdad
(c) Bangalore
(d) Damascus

28. The first edition of IP was published in


(a) 1965
(b) 1975
(c) 1955
(d) 1985

29.The "Pharmacy Act" came in force in


(a) 1947
(b) 1948
(c) 1949
(d) 1950

30. Pharmacy Council of India (PCI) was established in


(a) 1947
(b) 1948
(c) 1949
(d) 1950

31. What is USP?


(a) The United States Pharmacology
(b) The United States Pharmacy
(c) The United States Pharmacopoeia
(d) The United States Pharmaceuticals

32. Drugs converted to suitable form are known as


(a) Excipient

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(b) Source of drug


(c) Dosage form Full form of "MDI"
(d) API

33.full form of
(a) Metered Dose Inhaler
(b) Metered Dose Inhalation
(c) Metered drug ingestion
(d) Metered drug infusion

34. Every dosage form is a combination of drug and different kind of non-drug
components are called
(a) Additives
(b) Non-Additives
(c) New chemical entity
(d) All of these

35. Capsules in which powders are enclosed are made up of


(a) Gelatin
(b) Rice flour
(c) Fructose
(d) Dextrose

36.Concentration of Simple syrup USP is


(a) 85% W/V
(b) 76% W/V
(c) 95% W/V
(d) None of these

37. In purified water the concentration of sugar according to IP is


(a) 67% w/w
(b) 66.7 % w/w
(c) 77% w/w
(d) 65% w/w

38.The syrup is a nearly saturated solution of


(a) Sucrose
(b) PEG
(c) Glycerine
(d) Sorbitol

39. The syrup is in nature


(a) Aqueous
(b) Non aqueous
(c) Gas
(d) Solid

40. Elixirs are

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(a) Hydroalcoholic solutions


(b) Aqueous
(c) Viscous
(d) Semi solids

41. Liniments must not be applied on the skin


(a) Swelled
(b) Broken
(c) Painful
(d) Normal

42. Which vehicle is used in a throat paints?


(a) Glycerine
(b) Water
(c) Syrup
(d) Solutions

43. Posology is a branch of pharmacy which deals with


(a) Study of dosage forms
(b) Study of doses
(c) Study of drug interaction
(d) All of the above

44. Pediatric doses are lesser than normal doses because


(a) Of their lower body size
(b) Of their lesser body weight
(c) Their immunity system is not well developed
(d) Immature state of their hepatic and renal function by which drugs are inactivated
and eliminated from the body

45. Some drugs are advised before meals to


(a) Avoid dose dumping
(b) Avoid interaction with foo(d)
(c) Improve absorption.
(d) Both B & C

46. A lesser dose is required if the drug is given by


(a) Oral route.
(b) Topical route.
(c) Intravenous route
(d) None of the above

47. The prescription is an order written by a registered medical practitioner to


(a) Patient
(b) Pharmacist
(c) Compounder
(d) Nurse

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48. In which language the abbreviations in the prescription writing is very


common especially in dosage Instruction
(a) Latin
(b) Greek
(c) French
(d) French

49. The superscription is represented by a symbol


(a) Rx
(b) De
(c) Doc
(d) Ph

50. In the day of mythology, the symbol Rx, was considered as a prayer to
(a) Jupiter
(b) Jesus.
(c) Neptune
(d) Dhanvantari

51. The abbreviation of Latin word Rx, is


(a) You take
(b) To make
(c) To sold
(d) To use

52. Powders used for external use are


(a) Dusting powder
(b) Bulk powder
(c) Divided powder
(d) Effervescent powders

53. Bulk powders are


(a) Potent
(b) Non-potent
(c) Both a and b
(d) None

54. Insufflations are introduced into which of these body cavities Non-potent
(a) Nose
(b) Throat
(c) Ears
(d) All of the above

55. Powders are more stable than


(a) Syrup
(b) Tablet
(c) Capsule
(d) Elixirs

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56. A suitable is added to maintain the powders until the mass becomes coherent
but not too damp
(a) Colouring agent
(b) Flavouring agent
(c) Sweetening agent
(d) Granulating agent

57. What will increase the bulk of product?


(a) Processing aid
(b) Diluent
(c) Granulating Agent
(d) Organoleptic additive

58. According to IP 2007, oral powders are


(a) Finely divided
(b) Bulk powders
(c) Effervescent powders
(d) Douche powders

59. Which powder must be sterilized before their use?


(a) Medicated dusting powders
(b) Non medicated powders
(c) Natural dusting powder
(d) Surgical dusting powders

60. The monophasic liquid dosage form is ________ solutions.


(a) True
(b) Course
(c) Fine
(d) Micro

61. The component present in solution in small quantity is known as


(a) Solvent
(b) Solution
(c) Solute
(d) Liquid

62. The component present in solution in large quantity is known as


(a) Solvent
(b) Solution
(c) Solute
(d) Liquid

63.Solutions are dosage form


(a) Monophasic
(b) Biphasic

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(c) Triphasic
(d) Solid

64. Nasal drops should have pH


(a) 5-6
(b) 6-7
(c) 7-8
(d) 8-9

65. Nasal drops are


(a) Isotonic
(b) Hypertonic
(c) Hypotonic
(d) None

66. Buffering agent is also called as


(a) Sweetening agent
(b) Thickening agent
(c) pH modifiers
(d) Wetting agent

67. Saccharin is an example of


(a) Natural sweetening agent
(b) Flavouring agent
(c) Artificial sweetening agent
(d) Humectant

68. Suspending agent imparts


(a) Solubility
(b) Viscosity
(c) Absorption
(d) Wetting

69. Disodium EDTA is an example of


(a) Sweetening agent
(b) Flavouring agent
(c) Chelating agent
(d) Preservative

70. Which of the following is natural colorant?


(a) Amaranth
(b) Erythrosine
(c) Tartrazine
(d) Eosin

71. Cochineal is a
(a) Flavouring agent

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(b) Sweetening agent


(c) Coloring agent
(d) Thickening agent

72. Which of the following is anti-foaming agent?


(a) Methyl cellulose
(b) Aspartame
(c) Sucrose
(d) Simethicone

73. Which of the following is not a vehicle?


(a) Glycerol
(b) Water
(c) Butylated hydroxyl toluene
(d) Rose water

74. Cetrimide and Macrogols are an example


(a) Sweetening agent
(b) Colouring agent
(c) Emulsifying agent
(d) None of these

75. What type of emulsion is a w/o/w emulsion?


(a) Primary emulsion
(b) Micro-emulsion
(c) Multiple-emulsion
(d) Monoemulsion

76. The tail of a surfactant molecule is oil-loving or known as


(a) Hydrophilic
(b) Lipophobic
(c) Lipophilic
(d) Hydrophilic

77. In the stability of emulsion, which important instability step should be


prevented?
(a) Breaking
(b) Coalescence
(c) Flocculation
(d) Creaming

78. Which dye is used to identify type of emulsion?


(a) Scarlet red
(b) Scarlet green
(c) Crystal violet
(d) Methylene blue

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79. In conductivity test, if bulb glows on passing electric current so what would be
the type of emulsion?
(a) W/O emulsion
(b) O/W emulsion
(c) Micro emulsion
(d) Multiple emulsion

80.In micro emulsion, the size of globules are


(a) 1 um
(b) 0.1 μm
(c) 0.01 μm
(d) 10 μm

81. If viscosity of continuous phase increase so creaming


(a) No change
(b) Increase
(c) Decrease
(d) None of the above

82. In case of coalescence


(a) Dispersed droplet does not fuse
(b) Globules size decrease
(c) No of globules increase
(d) Dispersed droplets tend to fuse

83. Which of the following is not an example of a water-in-oil emulsion?


(a) Cod liver oil
(b) Butter
(c) Cold cream
(d) Milk

84. Which of the following statements regarding emulsions is false?


(a) Emulsions cannot be separated into their constituent liquids
(b) Emulsions show Brownian motion
(c) Emulsions show Tyndall effect
(d) Emulsions exhibit properties like

85. Creaming is
(a) Reversible
(b) Irreversible b
(c) Both a and
(d) Difficult to predict

86. Upward creaming is observed in


(a) W/O
(b) O/W
(c) Both
(d) Micro

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87. The particle size in suspension is


(a) less than 10 nm
(b) 102 nm
(c) Greater than 10 nm
(d) 10 nm

88. Pharmaceutical suspensions are generally


(a) Flocculated
(b) De-flocculated
(c) Both
(d) None

89. Rate of sedimentation is high in?


(a) Flocculated suspension
(b) De-flocculated suspension
(c) Both
(d) None

90.Cake formation is characteristic feature of


(a) Flocculated suspension
(b) De-flocculated suspension
(c) Thixotropic suspension
(d) Structured suspension

91. For ideal suspension, the sedimentation volume should be


(a) Zero
(b) Equal to one
(c) More than one
(d) Less than one

92.Immiscibility of oil and water can be overcome by


(a) Formulating an emulsion
(b) Formulating suspension
(c) Formulating an insufflation
(d) Formulating an elixir

93. Suppository bases


(a) Cocoa butter is an example
(b) Helps in insertion into the body cavity
(c) Theobroma oil is an example
(d) All of the above

94. Which of the following is an advantage of suppositories?


(a) Need to store at low temp.
(b) It's cost
(c) Drug may be degraded by microbial
(d) Can be given to unconscious patient

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95. A suppository is generally intended for use in


(a) Rectum
(b) Vagina
(c) Urethra
(d) All the above

96. Vaginal suppositories also called as


(a) Pessaries
(b) Simple suppositories
(c) Bougies
(d) None

97. Which of the following method is used to manufacture suppositories


(a) Hand moulding
(b) Compression moulding
(c) Pour moulding
(d) All the above

98. Which of the following is most commonly used suppository base


(a) Cocoa butter
(b) PEG 1000
(c) PEG + Hexanetrioly
(d) None

99. Which of the following method is simple and oldest method of preparation of
suppositories?
(a) Pour moulding
(b) Hand moulding
(c) Compression moulding
(d) All the above

100. Suppositories are generally evaluated by


(a) Melting range test
(b) Breaking test
(c) Liquefaction
(d) All the above

101. Advantages of plastic containers


(a) Poor conductor of heat
(b) Sufficient mechanical strength
(c) Easily transported
(d) All of the above

102. Methods of Extraction


(a) Infusion
(b) Decoction
(c) Maceration

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(d) All of the above

103. Advantages of water as a solvent for Extraction


(a) Non-toxic
(b) Non inflammable
(c) Suitable for various types of constituents
(d) All of the above

104. Menstrum is a drug residue which remains after extraction


(a) True
(b) False

105. Capsules are a solid dosage form in which the drug substances are enclosed
in a water-soluble shell
(a) True
(b) False

106. pH of small intestine is


(a) 1-2
(b) 3-4
(c) 6
(d) 7-8

107. Perforated pan is used for


(a) Sugar coating
(b) Film coating
(c) Both a and b
(d) None of the above

108. Empty capsule has moisture content in the range of


(a) 60%
(b) 12-15
(c) 50-70%%
(d) 30%

109. Soft gelatin capsule should not contain more ppm of iron as impurity than
(a) 5
(b) 15
(c) 40
(d) 60

110. Enteric resin used for coating is


(a) Cellulose acetate Pthalate
(b) Zein
(c) Shellac
(d) All of the above

111. Base for chewable tablets include

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(a) Mannitol
(b) Glucose
(c) Lactose
(d) None

112. Enteric coated tablet disintegrate in


(a) Stomach
(b) Liver
(c) Intestine
(d) Mouth

113. Hardness of tablet is measured by


(a) Pfizer tester
(b) Erweka Tester
(c) Strong Cobb
(d) All of the above

114. Whiskering (a tablet defect) is observed with the use of punch


(a) Convex
(b) Flat
(c) Concave
(d) Biconvex

115. Shells of gelatin capsules is made elastic by adding


(a) Sorbitol
(b) PEG
(c) Povidone
(d) Lactose

116. How much amount is accepted to dissolve in a dissolution medium in 20


minute at 50 rpm?
(a) Not less than 70%
(b) Not more than 80%
(c) Not less than 80%
(d) 80%

117. What's the role of cam tracks in tablet compression machines?


(a) For proper movement of the punches
(b) For proper movement of the granules
(c) For proper movement of both (granules and punches)
(d) For movement of granules and hopper

118. Which tablet compression machine is best for compression of granules?


(a) Single Press
(b) Longitudinal Press
(c) Rotary Press
(d) Stamping press

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119. Which capsule size number has the maximum capacity?


(a) 5
(b) 1
(c) 0
(d) 000

120. The 000 size capsules can fill the volume of


(a) 1000 g
(b) 500 mg
(c) 250 mg
(d) 750 mg

121. is used for bulk handling, warehouse storage and transport shipping. The
most common form is a palletized unit load that packs tightly into containers
(a) Primary packaging
(b) Tertiary packaging
(c) Quaternary packaging
(d) Secondary packaging

122. Packaging Testing includes


(a) Shock test and drop test
(b) Vibration test
(c) Inclined Impact test
(d) All of the above

123. Disadvantages of plastic material in packaging


(a) Release alkali to aqueous preparation
(b) It is fragile so easily broken
(c) They react with certain chemicals
(d) Absorption permeable to moisture

124. Which is a capsule filling machine?


(a) Osaka
(b) Jaansun
(c) Macofar
(d) All of the above

125. Gelatin is hydrolysed product of


(a) Pectin
(b) Tannin
(c) Shellac
(d) Collagen

126. Which of the following industrial dryer is used to dry tablet granules?
(a) Drum Dryer
(b) Fluidized bed dryer
(c) Spray dryer

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(d) Freeze Dryer

127. Process control is carried out


(a) before production
(b) during production
(c) after production control
(d) All of the above

128. A lipid bilayer structure that encloses an internal aqueous volume is known
as
(a) Niosome
(b) Liposome
(c) Solid lipid nanoparticle
(d) Nanoparticle

129. A spherical solid lipid particle prepared from physiological lipid, dispersed
in water or in aqueous surfactant solution
(a) Solid lipid nanoparticle
(b) Liposome
(c) Niosome
(d) Nanoparticle

130. A non-ionic surfactant based multilamellar or unilamellar vesicular


structure
(a) Microspheres
(b) Liposome
(c) Niosome
(d) Nanoparticle

131. This particulate system is also known as bodies of water


(a) Aquasome
(b) Liposome
(c) Niosome
(d) Dendrimer

132. What does QA and QC stand for?


(a) Quality assurance and Queuing control
(b) Quality adjustment and Quality completion
(c) Quality assurance and Quality control
(d) Quality adjustment and Queuing control

133. What is QA?


(a) It is the measurement of degree to which a product satisfies the need
(b) Any systematic process used to ensure quality in the process
(c) Process of identifying defects
(d) It is a corrective tool

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134. Standard unit volume in metric system is


(a) Microlitre
(b) Millilitre
(c) Centilitre
(d) Litre

135. Colloidal mill is suitable for manufacturing of


(a) Emulsion
(b) Ointment
(c) Tooth paste
(d) Suspension

136. Indicate which of the following statements is true. Oil soluble surfactants:
(a) Have high HLB values
(b) Are hydrophilic
(c) be used as emulsifiers to produce water-in-oil emulsions
(d) Are efficient solubilizing agents

137. Which of the following properties are characteristic of microemulsions?


(a) High surfactant content
(b) Droplet size greater than 1 nm
(c) Transparent systems
(d) Thermodynamically stable

138. Which of the following properties are characteristic of deflocculated


suspensions?
(a) Close packing of the sediment to form a cake
(b) Higher sedimentation rate
(c) Formation of flocs
(d) Rapid clearance of supernatant

139. In micro-emulsion pan coating process size solid particles are used
(a) 35-5000 micron
(b) 2-600 micron
(c) 5-300 micron
(d) 600-5000 micron

140.Bloom strength of gelatin ranges from


(a) 50 to 150 g
(b) 100 to 200 g
(c) 150 to 250 g
(d) 200 to 300 g

141.The viscosity of gelatin can range from


(a) 25 to 45 millipoise
(b) 30 to 50 millipoise
(c) 30 to 50 poise

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(d) 25 to 45 poise

142. A polysorbate has a molecular weight of 1300, an ethylene oxide weight


percentage of 68 and a sorbitol weight percentage of 14. The HLB of this
surfactant is
(a) 15.0
(b) 13,6
(c) 16.4
(d) 2.8

143. Following statement is true for lotion except;


(a) Aqueous/alcoholic solution/suspension in aqueous media
(b) Applied with fraction
(c) Applied on broken skin
(d) None of the above

144. An elixir contain 38% v/v alcohol, what is proof spirit according to USP?
(a) 76%
(b) 70%
(c) 66.61%
(d) 64.35%

145. Which of the following is used as suspending agent in parenterals?


(a) Gelatin
(b) Pectin
(c) Both (a) and (b)
(d) None of the above

146. 1 ml is equal to how much minim?


(a) 30
(b)15
(c) 1
(d) 10

147. In Clerk's formula, weight is mentioned as


(a) Pound
(b) Gram
(c) Kilogram
(d) Grain

148. Cold cream is also known as


(a) Foundation cream
(b) Soft cream
(c) Skin moisturizer
(d) Skin protective

149. Plasticizers are added in nail liquors to provide to film


(a) Hardness

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(b) Flexibility
(c) Toughness
(d) Softness

150. Which of the following test is performed for lipsticks?


(a) Breaking
(b) Washability
(c) Elasticity
(d) None of the above

151. Which of the following is not moulding-related problem in lipstick?


(a) Laddering
(b) Cratering
(c) Deformation
(d) Sweating

152. Product size of 1-30 microns may be obtained using


(a) Roller mill
(b) Hammer mill
(c) Fluid energy mill
(d) Cutter mill

153. Particle size reduction will not enhance the absorption of


(a) Hydrophobic compounds
(b) Hydrophilic compounds
(c) Weak acids
(d) Weak bases

154. Following are the examples of O/W emulsion except


(a) Milk
(b) Shaving cream
(c) Cold cream
(d) Vanishing cream

155. Following ratio is used for the preparation of emulsion


(a) Fixed oil: Water: Gum (4:2:1)
(b) Volatile oil: Water: Gum (4:4:2)
(c) Both of the above
(d) None of the above

156. Young rule is


(a) Child dose = (Age in year/age + 12) × Adult dose
(b) Child dose = (Age in year/20 +12) × Adult dose
(c) Child dose = (Age in month/150+12) × Adult dose
(d) Child dose = (Age in month/20+12) × Adult dose

157. 1 drop is equal to how much ml


(a) 0.6

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