MCQ

A patient who must take verapamil for hypertension and angina has become constipated. Which of
the following drugs would be most suitable as a long term laxative?

A. Aluminum hydroxide

B. Diphenoxylate

C. lactulose

D. Metoclopramide

E. Mineral oil

A pregnant woman with 28 weeks gestation complaining of distressing constipation. Which of the
following drugs can be prescribed safely?

A. Ondansteron

B. Lactulose

C. Senna

D. Magnesium sulphate salt

E. Castor oil

Bisacodyl frequently can cause:

A. Abdominal cramps

B. Constipation

C. Skin rashes

D. Dizziness

E. Nauseas
Castor oil is classified as which type of laxative?

a- Lubricating laxative

b- Anthraquinone laxative

c- Irritant laxative

d- Stool softening laxative

e- Bulk producing laxative

Which one of the folowing drugs is NOT a laxative agent?

a- Methyl cellulose.

b- Diphenoxylate.

c- Liquid paraffin.

d- Lactulose.

e- Bisacodyl.

Apatient who is taking verapamil for hypertension and angina has become constipated. Which of
the following drugs is an osmotic laxative that could be used ot treat the patient's constipation?

a- Aluminum hydroxide

b- Diphenoxylate

c- Magnesium hydroxide

d- Metoclopramide

The bulk laxative is one of the following :

a) Mg sulfate

b) Castor oil

c) Bran

d) Liquid paraffin

e) Senna
Irritant laxative include all the following except :

a) Castor oil

b) Bisacody!

c) Diphenylmethane

d) Lactulose

e) Anthraquinone derivative

70 year old patient presented with weakness, tiredness and ms cramps. the ECG shows QT
prolongation, Flatting of T wave and occasional A-V block. his serum K was low ( 2.8 mequ/I) . he
admitted taking laxative every day for the past several months, which laxative could be responsible
for the above condition:

a) Bisacodyle

b) Liquid paraffin

c) Methycellulose

d) Bran

Patient presented with abdominal pain and frequent unsatisfactory bowl movement, for the last
one year has been using purgative twice weekly to open his bowl, on clonscopy, the colon was
found to be atonic with bluish pigmentation of mucosa . which of the following the most likely
purgative that patient has using :

a) Liquid paraffin

b) Ispaghula

c) Senna

d) Lactulose

The following laxative lower the blood ammonia level in hepatic encephalopathy :

a) Biscodyle

b) Liquid paraffin

c) Lactulose

d) Mg sulfate
All of the following drugs are generally well tolerated for the treatment of constipation except:

A. Castor oil.

B. Methylcellulose.

C. Polyethylene glycol.

D. Docusate.

A27-year-old woman who is 34 weeks pregnant is on bed rest and visits her obstetrician. During the
visit, she informs her physician that she has been experiencing mild constipation. Which of the
following medications NOT recommended to her?

A. Castor oil.

B. Lactulose.

C. Mineral oil.

D. Loperamide.

E. Bisacodyl

A27-year-old woman who is 34 weeks pregnant is on bed rest and visits her obstetrician. During the
visit, she informs her physician that she has been experiencing mild constipation. Which of the
following medications will most likely be recommended to her?

A. Castor oil.

B. Lactulose.

C. Mineral oil.

D. Loperamide.

E. Bisacodyl
Select the mechanism by which stimulant laxatives increase defecation ?

a) Soak up water and distend the large intestine and so, stimulation of peristalsis.

b) Irritate the mucosal lining of the intestine and directly stimulate peristalsis.

c) Coat the fecal matter and prevents water absorption from it.

d) Facilitate incorporation of water into the intestinal contents and soften the fecal mass

e) Retain water by their osmotic effect and so, stimulation of peristalsis.

45-years old patient taking verapamil for hypertension and angina for several months. He
complains today of constipation manifested by decreased stool frequency and often needs to
strain to evacuate his bowels. An abdominal radiograph reveals large amounts of stool in the colon
with no signs of obstruction. The patient try to treat his condition by increasing the fiber in his diet
but it is no longer effective. Which of the following drugs is an osmotic laxative that could be used
to treat the patient’s constipation?

A-Aluminum hydroxide

B-Diphenoxylate

C-Magnesium hydroxide

D-Metoclopramide

E-Ranitidine.

Written
Enumerate the 6 Types of Laxatives

Mention the mechanism of action and therapeutic uses of:

1-Senna
2- Bisacodyl
3- Castor oil
4- Bulk laxatives
5- Saline and osmotic laxatives
6- Stool softeners

7- Lubricant laxatives

8- Chloride channel activators