Drug name

Generic:AMOXICILLIN Brand:Apo-Amoxi

Action: antiinfective; antibiotic; aminopenicillin System:

Mechanism of action Side effects Adverse effects

Amoxicillin is bactericidal to susceptible microorganisms. It inhibits cell wall synthesis.

Side Effects of Amoxicillin

GI disturbances (mild diarrhea, nausea, or vomiting) Headache Oral and Vaginal Candidiasis Generalized Rash Urticaria

Adverse Reactions of Amoxicillin

Superinfections Severe hypersensitivity reactions (anaphylaxis, acute interstitial nephritis) Potentially fatal antibiotic colitis ( abdominal cramps, watery svere diarrhea, fever) Nursing Implication Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy, start drug pending results; periodic assessments of renal, hepatic, and hematologic functions should be made during prolonged therapy. Monitor for S&S of an urticarial rash (usually occurring within a few days after start of drug) suggestive of a hypersensitivity reaction. If it occurs, look for other signs of hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately. Report onset of generalized, erythematous, maculopapular rash (ampicillin rash) to physician. Ampicillin rash is not due to hypersensitivity; however, hypersensitivity should be ruled out. Closely monitor diarrhea to rule out pseudomembranous colitis. Patient & Family Education Take drug around the clock, do not miss a dose, and continue therapy until all medication is taken, unless otherwise directed by physician. Report onset of diarrhea and other possible symptoms of superinfection to physician (see Appendix F). Do not breast feed while taking this drug without consulting physician

Drug name

Generic:Clindamycin Brand: Klindex

Action: antiinfective; antibiotic System:

Mechanism of action

Bacteriostatic. Clindamycin binds to bacterial ribosomal receptor sites. Topically, it decreases fatty acid concentration on skin. It inhibits protein synthesis of bacterial cell wall and prevents outbreak of acne vulgaris.
Side Effects of Clindamycin Abdominal pain Nausea and Vomiting Diarrhea Vaginitis and itching Dry scaly skin Phlebitis, thrombophlebitis with IV administration Pain, induration, at the IM injection site Allergic reaction, urticaria, pruritus Headache and dizziness Contact dermatitis Hypersensitivity reaction

Side effects Adverse effects

Adverse Reactions or Toxic Effects of Clindamycin Antibiotic-associated colitis (Severe abdominal pain, tenderness, fever, watery and severe diarrhea) Blood dyscrasias (Leukopenia and thrombocytopenia) Nephrotoxicity (Proteinuria, azotemia, oliguria)

Nursing Implication

Store capsules at room temperature After reconstitution, oral solution is stable for 2 weeks at room temperature. Do not refrigerate oral solution to avoid thickening. Give with 8 oz water. Question patient for history of allergies, particularly to clindamycin, lincomycin, and aspirin. Avoid concurrent use of neuromuscular blocking agents. Monitor bowel activity, stool consistency; report diarrhea promptly due to potential for serious colitis. Assess skin for rash with topical application. Assess for superinfection: severe diaarhea, genital/anal pruritus, increase fever, and change of oral mucosa.

Continue therapy for full length of treatment. Doses should be evenly spaced. Oral doses should be taken with 8 oz water. Caution should be used when applying topical clindamycin concurrently with peeling/abrasive acne agents, soaps, alcohol-containing cosmetics to avoid cumulative effect Do not apply topical preparations near eyes, abraded areas. If accidental contact with eyes, rinse with cool tap water. Do not engage in sexual intercourse during treatment.

Drug name Mechanism of action

Generic:Ferrous sulfate Brand: Feosol

Action: supplemental vitamins System:

Ferrous Sulfate is an essential component in the formation of hemoglobin, myoglobin and enzymes. It is necessary for effective erythropoiesis and transport or utilization of oxygen.
Side Effects of Ferrous Sulfate Mild, transient nausea Heartburn Anorexia Constipation Diarrhea Adverse Reactions of Ferrous Sulfate Large doses may aggravate peptic ulcer, regional enteritis, and ulcerative colitis. Severe Iron Poisoning: Vomiting Severe abdominal pain Diarrhea Dehydration Hyperventilation Pallor or cyanosis Cardiovascular collapse

Side effects Adverse effects

Nursing Implication

Store all forms at room temperature. Give between meals with water but may give with meals if gastrointestinal discomfort occurs. Transient staining of mucous membranes and teeth will occur with liquid iron preparation. To avoid, place liquid on the back of the tongue with dropper or use straw. Avoid simultaneous administration of antacids or tetracycline. Do not crush sustained-release preparations. Eggs and milk inhibit absorption. Monitor serum iron, total iron-binding capacity, reticulocyte count, hemoglobin, and ferritin. Monitor daily pattern of bowel activity and stool consistency. Assess for clinical improvement, record of relief of symptoms (fatigue, irritability, pallor, paresthesia, and headache). Expect stools to darken in color. If gastrointestinal discomfort occurs, take after meals or with food.

Drug name Mechanism of action Side effects Adverse effects Nursing Implication

Generic: Brand:

Action: System:

Drug name Mechanism of action Side effects Adverse effects Nursing Implication

Generic: Brand:

Action: System: