rdre thrtomniomal nhercidencA/ CYtoplamal hhertuHeunc

The topAumse hhettonca due to tho Puma

genes DARO cn ceu Otgauns 9RAOd+tol mitochonclea\

() Rauuprocod oleronce ho

onpureH aennou Ahe

fLma Aenes rom ony
ena o e t or ArdndmeHeof s hondmenon,
n narantey enherutanu
Le dArAH)
P.
donot hDw
a ustoLubnoituy thhir
rcot. reaakttr4aaAeR) s*perttnteN tt4eLQo,

urAuur segeachorD h be'pawnted ch horce'Heant

T

HrcanmuHea Ao H jrogeny had unoca9

loren

sPomu aene genrta aho sirtgeut guwuna

N
mtor ncondttct u u ( oranaui rhale
N

Accocoicbneth oHane ONR

.

DNA fort e-
Oo ued weh , ep oNA Aemyolsmocw
uptomytuh rentani cuc L DLA
cweh
UtesNOM gomemutesenoor QsL hhlulumbreinue

nuciLa eies art AD oHetes ly am.Inclurndn d

Lak aLocder) wtth a purtotnde, dm kebnt Ort Vercu
hheut chartaar
munyM COLs a tytofaomut o
vekus frat
es ouko dfe twtth a pcursie, bpnblont ort

Anaun cee fdr Uttolpmt'cchkieejana

r mgtocheonglru'al
Ice conurenioeth 2itHOrthlortoC

Suh ctAQJ ferto

ari ortaneuu dhhotteLnd
tnhorelancA.
on l04dd thhUrl4en_ ort mgto thontlrida
PLcwtto thhorttteunig
been a plonAo nhoryeadk
AU ocut npwLage Culo0ut Lotd ed hortzexnca d based
Lornhyu

LQs.

orur outt)in 0'co pLunt

Leaes mirtotloud Jeutpa, he qo'clocA L0unt
mOH lhAren, cuhuH G trtuaJeo&o m rttrch
n a n on cuhi brt onky varuLgeLed

a.maps+h Tloeuru Froduc o ho 3 p rtnches

when DuRH, rom a rli) brtonch eulr
use ouomal H a Praeny cöere r l crropetive
hPanApe er, uhle or vadue geuted thsmGLl
euund. 3chidsurtly t-Datny rom th ertose ahwkbthy
AowOru com u n orun thes th femal ardt
eora uah truroitie of ho mauu Loweris bouh
Htom egrclnehiR o a n t t o brtounch. ethha
froan ioith ou4. Cris ay nvwlbchglorer trom
acilAlebrcanchy aus he temoul
fltntACg Arikn
 CAay the phenotY
furon u r . veLrtu geeo. "theJe roruld may bo eulountg

axAMong4 thot
nmureobx jdpa ccleo{ h pAiUAea. conopot
dd4erandadrrom fro flwkHo| ro posHblU houvchg the
mutat pLoLm anaouHertn-koLR «hto eorrtli
onDrmay chiDrtDplCLt whi'l hoR hacny dho nrema
a u olONLDp thto nDrUnau Araan thi ocdp\0ut

RLet hÜNote
ortanh Uptol dh brtanchuseel
meil fcurten mall pCLrnt

. re Cnrcoo
Cnraer
a. while Onr ) )
3.vcruegeukeo Cnro

cuh .nreN
. uhie cn
3.vCUugoueo ceh
N
-0
WOUru seuteol 1. nrcO CnrD, chuJa,
yartiesaeot
3.varujato
vau'ae ceuh
 Conclw
foreftutdutthg- bool koralrzeal t h a HdofAoLh. ThkOuk
tnown o PAtom. TheRL Arandneleo genrtoatten
Ouf-terr onUrat hrogh haa uyo plam courtudeol o
th DNUUL.
Mctochonolray n horuleun n ye00
yeost muBoehomoloul gpnome es Jutprcuchgy 1 u

EdoNho oluton can ocu9

dn4h nm dtz

mu4o-thDAdrulau unton, they suV th a t h _

Onrow anairohteai.oerert lo mlochoralu

ARN muteatom hat abtus mtochonalri funotd).

A1Culfoi Paaiue Rbo

Hooustng m D NA.Tha 4hR
onurunrtkb9 represen)
ruuiR th nou4an.
SeLrute paihes (Rhot-J
Heaernp0ru ALtgenbe Fraing from
-a 7 36 of #nortna
thopatraN
m ntaun arH S9tna cfs
ONA thosLERL
Coco.hi cofs ma cQS@Nt out sartol
as a
mulmarut csixe) tn Chdeh tho arie
aur hon eransod ch tanolky
olArtoc OHerded
sape,Som PlitH oLraddecblaAnu
ron&ebu tuhot UnRO hoinsesjpna

wwn a thok) a Croneo wh cudolthe2

r R MP from Korapuf
 ONA uSapfeary wmthom. hs a i t cc0oi
sures) tha o r t e o n of gre@gen in uhleh supun

m.ONA. Y0A nt 0NA ha E Jpeiulfet daquenu

ALhg ouna CA duruee.Thes hduteathot

enNcopnolin repukatao eiha an sejnti af

0 NA tan bprent a pRAKIR

Malerrna ofuen n Sh cerUng en Sneu

aLAn hreouyh fert fmocluco hren

tnduh f

teeeuests oiLtoCLroU ruht ou NBen OL

sheu

aThoR coeo douurtou ha uft are setotrcu.

domuhant ano
The I c a Lotung
DVOrtneo ly ho en
D. D hyA-eou esckuhy
u &teremuheo ot tha d'.
T LARrihan of bqycoB,eluler &cuu k
tanaeby giveca ldeurtved: cnolce -heut hg
dRgna he_
har akert uf coelina 'ollteremtneo N

F o ollretemu c o wh sthyttxa ma
Ol ha f- dray foHR alltroa -thau. even th ha
tho otYaprahy Poney ollsvre holl
-celp al
 dlxa m au Aa
olteprin donol des

au otrpresnys doelo ora Eoe'2ing.

S o m F t h MaL ahth art@ homatodee)tor

CStny roy coligkaue d t e coun durc o
hanott
(a) oota ánuw uhbh arca genny forr JAtecA
aray Cotuhg uha-Hg maLor,
mau 4ho sprethgs eropeaee

ettopaum dau
maRtartna nDyI throu bart H+8fLu) oluters

han oHang. 113,19

.. .
Inheradarc hamo furtletle cn rasamium
Gonnebous& hi cusoudee hoo oluorbeo
Htrnkmvetio9 4 m ytopkmwtpurtcl wnDun a

Aogpa pkticu k. roliton to nuctotrRna_)

partameciun rtttu, tteol Indtindlua o partetèuln
COLLR LeuRo

&th cndinduauU Lra cae KijDr4he duveluau

Thurounetidi f heor Hralg contath

LOrgRno ardtU Hhhoirt toptay.Thor porcttdy
CLrta nou) 0Kaya parttHRs
Jary ubo nuuur oudol h t h u l def duyuitsuehg &

tn 4he nucius Dut hoconMrLol heredIHeary Artout

4h_halle chDurcouut
ALcthou a e parthel qLR toplmi
arthtA S 4re0nd-dteo) strut *Nruh tha uftofcum,
here ounteinctna f reohuLtUy "

YcPamti oirt
CoHtoleo a dosnotARA
K Proent ch +ha quotuy
C alto Utrath. haeHvdra) fOM)4

Ohenprcoy heit no aplarmue erthnaR

N Tisd3 9,

duurtira 6oridgettm bauon *ha haR no onn 10utR

Pouruttu As a reAcut Hha Jeruet cl rmauy senaHtie

onusaiion &rtscluck) s0ntte prrogen

utuna mjugeteon & t Juh cmg) tooth hnmald

otd aruhe bebm A}lon Ait ytoplam coniaun

diaro oplataymundh

y topta r) 4tdhorut
Egp parte

rc.ou rioftcen) uthaf

LHlotatrcca) Sernle
fauraua rta

Shprtt olureli ton

enconset( fralyRnjugcu
wtho
toptame
dcheungR
ko Sendte tiopicttm

artltey
eive coc)
conugaieo
dh dgta4pinu,
|hitlest eDhdeeeroudtn dentil ounen
(nhenuleun tAr
Sente. Chaurcauèry olurtig

tulLe

,1
 inottvtouoD ho{ Vatn ben
4utort, Rnduetiuy may heesHAst_o i t o
Rurtfe l ort not

piot) mudrtebo.1 Ca0 MHhb

C10 mlkoc) th druoopht ta
Thu sehinoyua t oielageo Muulet. H eo
erto
B- Rngdes a denbinkaol domrn mulatc) (haoluuhy
oct-hope e . H uao o muther ortPlo
I-Strencd fort a ruterste utihal mutenB raent o
hO T-thruomobma emal olrcoophi1a hoMo?{tou
Fort heR JRNR mall hemuanpuy r nOn~vcbubli .
3. C { rfrruonB Ro vortnn h t preuents rcohy
a

OVet can the tvoruaol ueont, era T k ar

Lvoyo n hu inverdeol sedhant.
The & ard mhuutale Hoptko ch
tAL J&mo chrompom. ConuuenHA o eL temdley (
Tdotee ybanR haol) auruheTHvw For thes
A LDD donng fomathoiDEH0U tor tha Cib Urcompbme

o senuhuoo rrLiA ltPROLY muteuten hotuc t b

drtDophoua male. MullN mau a eroy b4) haRsco

Chromcbn caolsarteo maik.

ThaPert+ urto-eln resulkhy trum h2rem
h 'eLO bdiureoenmoul aermoute cuh a
A

butt no malo 1t im00 au mag3

6
birc 242e m a
wth Uhronorom
em uy Condtd).
w_uwr au maua h strraoLRo -Chrcomanr ao
nduicouteo hot mutelton has feLhan
loLea on ho -chromoOM_u rLOolbuHeol mlk fvoU
R M rtaoutr). ToraHora tne-Ckredpeta
riogeryonnitot on enmou m e t y ehdradeuas
yRootb nut
6oy. Suruveha mouot froery
 Gneu Co
MCLertna nuena d9 heu colng c)Snu
tnsra

00nra Scnirtra

(crtos derttLthattn) DD (Cron)

Jtrystra elutra

Dq
n4e
Crors
sinatra Dertray 0.enca
D
DD
DD

dendra dRradeu nustta

Dodtrro

DeNda d0kal 0tka 4tsko Ooutrca Dena 6eNdrco sntra

olNArca hudtKal aaikuhy

kanorCma nheu tane_
Dereara dhgruN A moLrena ehtuen
in snu cou