Q1. Cystic fibrosis (CF) is a recessive genetic disorder.

The recessive allele is

shown as f and the dominant allele as F. The family pedigree shows the inheritance
of cystic fibrosis (CF). Both parents are heterozygous for CF.

(i) State what is meant by the term heterozygous.

(1)
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(ii) Explain why Rebecca does not have CF.

(2)
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Q2. The earlobes of an individual are detached or attached. This is determined by
the alleles inherited from their parents.

An individual with attached earlobes must have inherited two recessive alleles
from each of their parents and will have the genotype ee.
(i) State the genetic term used to describe an individual with the genotype ee for
attached earlobes.
(1)
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(ii) A female with the genotype ee has attached earlobes and a male with the
genotype Ee has detached earlobes.
Complete the Punnett square to show the gametes and genotypes of the
offspring for this female and male.
(2)

(iii) State the probability of the offspring having detached earlobes.

(1)
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(iv) What is the percentage probability of a homozygous dominant mother and

homozygous recessive father producing a child with attached earlobes?
Put a cross ( ) in the box next to your answer.
(1)
A 0%
B 25%
C 75%
D 100%
Q3.

(a) Complete the sentence by putting a cross ( ) in the box next to

your answer. Sperm cells and egg cells contain sex chromosomes. Egg
cells contain
(1)
A one X chromosome
B one Y chromosome
C two X chromosomes
D two Y chromosomes

(b) (i) Complete the Punnett square to show how the sex of a child is
inherited.
(2)

(ii) Calculate the percentage chance that a child will be female.

(1)

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Q7.
Eye colour inheritance
The diagram below shows the inheritance of eye colour in a family.
The allele for brown eyes is (B) and the allele for blue eyes is (b).

* Explain why two parents with the alleles BB and bb for eye colour are unlikely to
produce offspring with blue eyes. You should draw a genetic diagram or Punnett
square to help with your explanation.
(6)

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