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Sayan Misra · Follow

Honours/Distinction marks in Anatomy &
Biochemistry · 1y

RelatedWhat are the most important topics to

be remembered in biochemistry (1st year
MBBS)?
Thanks for requesting

So, once again, NOTE — It's going to be a long

answer as you all must be knowing , but again if
you cover up these topics well, then you can be very
sure of getting a good grade in Biochem too.

See, for most of the students, Biochem becomes the

most neglected subject in 1st yr (It was the same for
me too). The reason is because, most of us keep on
studying the mammoth, ie. Anatomy for the majority
of the time & then we give 2nd most importance to
Physio. Thus Biochem keeps on getting neglected &
we finally end up reading it just a few days before the
exam

Now, if I talk about the syllabus, it's Not that tough as

compared to the other two. Moreover, a lot of it is
already known to you from your class 11& 12. So, this
subject seems very easy. It really is easy & you can do
it few days before the exam only. But how?

THAT'S WHAT I'LL BE TELLING YOU HERE.

You just have to read all these topics (as it includes all
the important topics & the topics from which
questions have come in previous years) only from any
of the “Standard textbooks". That's it. And revise
them frequently & try writing them down somewhere.
This will help you out immensely.

So, let's start with the important topics chapter—

wise.

BIOCHEMISTRY

Protein Metabolism

SN

1. Metabolism of Tyrosine

2. Biogenic Amines

3. Metabolism of Glycine

4. Alkaptonuria

LAQ

1. Inborn Errors of Metabolism of Tyrosine* and

Phenylalanine

2. Formation and Fate of Ammonia**

3. Urea Cycle and Abnormalities***

4. Alkaptonuria - Biochemical Basis, Tests for

Diagnosis

5. Glycine - synthesis, inhibition, specialised

products formed

6. Transamination, Deamination, Ammonia

Toxicity

Nucleotide Metabolism

SN

1. Purine Salvage Pathway**

2. Hyperuricemia

3. Gout**

4. Catabolism of Purines

Hemoglobin

SN

1. Hemoglobinopathies and examples

2. Abnormal Hemoglobin** - changes in AA

sequence

LAQ

1. Catabolism of Heme*, Hemolytic Jaundice

2. Formation and Fate of Bilirubin; Jaundice

3. Biosynthesis and Degradation of Heme

4. Heme - biosynthesis, regulation*; Intermittent

Porphyria

Vitamins

SN

1. Coenzymes of Thiamine of Pyridoxine - two

biochemical functions of each

2. Functions of Folic Acid

3. Deficiency Manifestation of Vitamin A

4. Coenzyme Function of Folic Acid and B12

5. Wald's Visual Cycle

6. Activation of Cholecalciferol, Justification as a

Hormone

LAQ

1. Vitamin D

2. Vitamin A**

3. Vitamin B12 and Folic Acid

4. Vitamin C

5. Thiamine*

Enzymes

SN

1. Isoenzymes and Clinical Application***

2. Enzymes and Isoenzymes in Myocardial

Infarction**

3. Enzymes of Diagnostic, Analytic and

Therapeutic Importance*

4. Km Value

5. Activation Energy of Enzyme - E-S Complex

LAQ

1. Enzymes - definition, factors affecting enzyme

activity*

2. Enzyme inhibition - Competitive and Non-

Competitive

3. Enzymes - classification, examples,

Isoenzymes

4. Types of Enzyme Inhibitors

Biological Oxidation

SN

1. Substrate Level Phosphorylation

2. Oxidative Phosphorylation*** and

Thermogenin

3. Malate Aspartate Shuttle*

4. Inhibitors of ETC

5. Uncouplers of Oxidative Phosphorylation

6. Difference between Oxidative and Substrate

Level Phosphorylation

LAQ

1. Explain ETC, Mention Sites of

1. ATP Synthesis and Inhibitors of ETC**

2. Oxidative Phosphorylation

3. Explain ETC, Inhibitors and Uncouplers of

Oxidative Phosphorylation

Molecular Biology

SN

1. Genetic Code***

2. Mutation* - Causes and Types

3. Recombinant DNA Technology Application*

4. Reverse Transcription

5. DNA Replication

6. PCR

7. Lac Operon

LAQ

1. Protein Biosynthesis* and Inhibitors,

Regulation

2. DNA Replication, Two Inhibitors of Replication

3. Genetic Code- salient features, Wobble's

Hypothesis

4. Transcription, Post-Transcriptional
Modification, Two Antibiotics Inhibiting the
process

Proteins

SN

1. Biologically Important Peptides*

2. Secondary and Tertiary Structure of

Proteins**

3. TRNA And Its Functions***

4. Secondary Structure of Protein

5. Functional Classification of Proteins

6. Conjugated Proteins

Nucleotides

SN

1. Four Biochemical Functions of Nucleotides*

Free Radicals and Antioxidants

SN

1. Antioxidants

2. Antioxidant Enzymes*, Vitamins and Minerals

3. Free Radicals and Antioxidants

Nutrition

SN

1. Explain the Role of Dietary Fibres*

2. BMR - definition, factors

3. Protein Energy Malnutrition***

4. Kwashiorkor* - Biochemical Alterations and

Treatment

Carbohydrate Metabolism

SN

1. Significance of HMP Shunt*

2. Rapaport Leubering Cycle, Significance

3. Glycogen Storage Disease* - enzyme defects,

clinical manifestation

LAQ

1. Glycolytic Pathway in Erythrocytes,

Significance, Difference from Glycolysis

2. Glycogenolysis, Regulation, Glycogen Storage

Diseases*

3. TCA Cycle, Amphibolic Nature*

4. HMP Shunt*, Significance

5. Metabolism of Glycogen, Hormonal

Regulation*

Lipid Metabolism

SN

1. Cholesterol - biomedical importance

2. Cholesterol - metabolism, function

3. Lipoproteins*

4. Fatty Liver* and Lipotroptic Factors*

5. Ketosis

LAQ

1. Cholesterol Synthesis *** - name regulatory

enzyme, normal level, functions, explain

role in Atherosclerosis

2. Ketosis, Synthesis and Fate of Ketone Bodies

3. Beta Oxidation of Palmitic Acid, Regulation,

Energetics**

4. Roles of LDL, HDL in Cholesterol Transport,

Role in Atherosclerosis

5. Fate of Acetyl CoA, Fatty Acid Synthesis

Mineral Metabolism

SN

1. Regulation of Serum Calcium Level

2. Role of Calcium as Second Messenger

3. Absorption of Iron

LAQ

1. Plasma Calcium Level - hormonal regulation,

function, deficiency manifestation

2. Iron*

3. Calcium*

4. Calcium and Phosphorus

5. Copper and Zinc

6. Iron and lodine

7. Factors Influencing Calcium Absorption,

Functions

Integration of Metabolism

SN

1. Short Term Starvation - metabolic changes

2. Biochemical Changes in Starvation**

3. Most Severe Phase of Starvation -

biochemical changes

LAQ

1. Starvation Metabolism*

Acid-Base Balance

SN

1. Buffers**

2. Role of Kidney in Acid Base Balance

3. Any Two Buffer Systems

4. Metabolic Acidosis*, Its Compensation

LAQ

1. Metabolic Acidosis* - causes, explain

compensatory role of blood buffers and kidney

2. Blood PH - maintenance, disorders associated

with acid base balance

3. Water and Electrolyte Balance

4. Acid Base Balance, Imbalance, Causes

Plasma Proteins

SN

1. Immunoglobulin - diagram, describe any one

Ig in detail*

2. Functions of Albumin

Insulin, Glucose Homeostasis and DM

SN

1. DM - metabolic changes*

LAQ

1. Hormonal Regulation of Blood Glucose Level**,

Significance, Note on Glycosuria

Organ Function Tests

SN

1. Creatinine Clearance Test**, Explanation,

Significance

2. Urea Clearance

LAQ

1. Liver Function Tests** - enumerate, describe

LFT based on excretory function

Carbohydrates

SN

1. Hyaluronic Acid - biomedical importance

2. GAGS, Significance***

LCD

SN

1. Electrophoresis* - application, principle

2. Chromatography* -principle, application,

type*

3. Flame Photometer - principle, parts,

importance

Overview of Biophysical Chemistry

SN

1. Radioisotopes - diagnostic, therapeutic

significance, application**

Lipid

SN

1. Phospholipids - classify, examples, one

importance of each

2. Essential Fatty Acids

Digestion and Absorption

SN

1. Digestion and Absorption of Lipids

Hormones

SN

1. Group II Hormones - diagram, mechanism,

example

2. Name Different Types of Messenger

Hormones, Role of CAMP*

3. Mechanism of Hydrophilic Hormones

4. Mechanism of Steroid Hormones*

Cancer

SN

1. Tumour Markers*** - four examples

2. Oncogenes** and Proto-oncogenes*

3. Chemical Carcinogens*

Detoxification

SN

1. Conjugation** - examples

2. Detoxification by Oxidation and Hydrolysis

3. Metabolism of Xenobiotics - phase 1 reaction*

So, this is all. Again, you can take an ss of this or

bookmark this answer for your future reference.

Also, I repeat again, do these topics thoroughly &

revise them frequently with all the relevant cycles &
diagrams. I can tell you, you'll definitely do very well in
your exams.

So, that's all. Do mention in the comments if you have

any doubts

Also, I've already written answers regarding the

important topics which you have to read & remember
in Anatomy & Physiology. I've also mentioned the way
you have to go about these subjects so that it
becomes easier for you. I'm giving the links here. You
can go & check them out if you haven't seen them. I
can guarantee you, they'll definitely help you

Sayan Misra's answer to What are the most important

topics to be remembered in anatomy (1st year
MBBS)?

Sayan Misra's answer to What are the most important

topics in physiology for the professional exams?

Thanks & do upvote if you like my efforts & share with

your friends Also do follow me for more such
contents

Sayan
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Upvote · 282 30 26

AiR - Atman in Ravi · Follow

Spiritual Philosopher, Author, Singer · Fri

Promoted How does everyone have a different

soul?
The Soul, SOUL stands for a Spark Of Unique Life,
which means that your Soul is unique to you and my
Soul is unique to me. Think of light in a bulb. The light
in a bulb comes from the same source. But that light
in one bulb and electricity in the TV is different. As
long as it is in the bulb, it cannot light another bulb. It
is unique to that bulb. So, our Soul gives us life from
the moment of conception till the moment of death.
Do all the Souls come from the same source? Yes,
they come from SIP, the Supreme Immortal Power. At
the end, will they all go back to the supreme? Yes,
therefore the … Read more

Upvote · 5

Akshat Srivastava · Follow

MBBS in Bachelor of Medicine and Bachelor of
Surgery Degrees, All India Institute of Medical
Sciences Rae Bareli (Expected 2024) · 2y

Well if we have a look over the entire syllabus of

biochemistry for first year, then we will come across a
very good number of structures especially in the
metabolism part. Remembering all those structures is
physically not possible. So what to do now.?

Well, first of all while reading about any cycle or

aomerhing you can have a look at the structures to
identify how the changes are happening.

The basic biomolecules taught in the initial days gives

a good idea about structures. Focus more on them
including the anomers, epimers
Continue and such homologous
Reading
structures. They are asked in viva to boggle you

Upvote · 5

Sharmila · Follow
MBBS from GMC, Tamilnadu (Expected 2025) ·
Updated 10mo

What are some study plans for the

Related
MBBS 1st year?
Felicitations!!

I recently gave my first year proffesional exams.

Lemme share my experiences with three amazing

subjects!!

There's something common, to get noticed in all of

them.

Study from day 1, Don't grind. Be consistent

in learning, so that, you'll not have to stress
out at the end.

Continue Reading

Upvote · 343 12 14

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1. buy the book

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 4. let the guilt build up

5. when guilt reaches the threshold open the

book

6. read a few pages

7. remember why you weren’t able to read it

8. close the book

9. watch it

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ANATOMY

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Aiswarya Nair · Follow

MBBS in Bachelor of Medicine and Bachelor of
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No they are not necessary except for few exceptions

like nucleotides, basic structure of cholesterol, fatty
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phospholipid, glucose, fructose are some which I can
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But if you want you can go with structures ,I learnt

lipids and proteins along with the structures ,so I still
remember most of it

Upvote · 1

Aditya · Follow
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starting the journey of becoming a doctor .

In MBBS you cannot satisfy your hunger of knowledge

by reading a specific book.

It is a continuous process and in this process medicos

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of the writer.

Coming to first year:-

There are 3 subjects ,

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Upvote · 134 3 structures
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Swapnil · Follow
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I am not the best person to answer this. Biochem was
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Still.

To fight a war, you need

1. Tools : Good, standard textbooks. Harper is

one the best textbooks I have ever read. Very
clear in concepts. Though you may need
additional books too. Vasudevan is a good
Indian author. Or use any other book which
your seniors recommend since your final
proff paper is to be set from it. Keep reading
books regularly and make notes for last
minute revision. Those notes actually help
for the small topics which would otherrwise
get off
Signing ignored for the lack of time later.
Lippincott if you like Reading
Continue

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Amatullah Merchant · Follow

Medico, write to express. · Upvoted by Aishik Kundu,
MBBS Medical School & Medicine and Healthcare,
Medinipore Medical College (2022) · 4y

RelatedWhat is best possible way to do well in

exams when you are a 1st year student in
MBBS?
Thanks for A2A.

I'll segregate this answer in two parts, Do’s and

Don'ts.

Do’s.

1. Read standard books.

2. Complete your journals on time.

3. Pay proper attention during dissection. Learn

most of your practical anatomy here.

4. Concentrate on physiology practicals. Make

sure you know the calculations and methods
of hematology experiments.

5. Biochemistry practicals are sure shot. Learn

principle, observation and conclusion by
heart. You cannot afford
Continue to lose marks here.
Reading

6. Make notes of important topics. Notes

Upvote · 161 3 3

Rajah AR · Follow
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For exams, structures are not as such important.

But, studying them will be helpful for your

understanding of the subject.

Cycles are very much important for the exams.

Having said this, one can never predict the nature of

questions asked in university exams. So though the
probability is less, questions may come from
structures.

Hope this helps.

ATB

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Pushpanjali Juluru · Follow

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Thanks for the A2A.

I bought vasudevan despite my sister telling me it'll

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book and bought it anyway.

Deep inside I knew I bought it just for the glossy

pages *cringing*.

But by the time of exam I studied satyanarayana

meticulously. It is a fact that any information that is
read 4 times makes you way better than most
people in the room.

I did just that for biochemistry. I was second highest

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