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Full download Test Bank for Basic Immunology, 3rd Edition: Abul K. Abbas file pdf free all chapter
Full download Test Bank for Basic Immunology, 3rd Edition: Abul K. Abbas file pdf free all chapter
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Test Bank
MULTIPLE CHOICE
ANS: C
The immune system has evolved in the setting of selective pressures imposed by
microbial infections. Although immune responses to cancer may occur, the concept that
“immunosurveillance” against cancer is a principal function of the immune system is
controversial. Repair of injured tissues may be a secondary consequence of the immune
responses and inflammation. Although the immune system has regulatory features that are
needed to prevent excessive inflammation, prevention of inflammatory diseases is not a
primary function. The immune system can protect against microbial toxins, but it
generally does not offer protection against toxins of nonbiologic origin.
2. Which of the following infectious diseases was prevented by the first successful
vaccination?
A. Polio
B. Tuberculosis
C. Smallpox
D. Tetanus
E. Rubella
ANS: C
In 1798, Edward Jenner reported the first intentional successful vaccination, which was
against smallpox in a boy, using material from the cowpox pustules of a milkmaid. In
1980, smallpox was reported to be eradicated worldwide by a vaccination program.
Effective vaccines against tetanus toxin, rubella virus, and poliovirus were developed in
the 20th century and are widely used. There is no effective vaccine against
Mycobacterium tuberculosis.
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-2
3. A previously healthy 8-year-old boy is infected with an upper respiratory tract virus
for the first time. During the first few hours of infection, which one of the following
events occurs?
A. The adaptive immune system responds rapidly to the virus and keeps the viral
infection under control.
B. The innate immune system responds rapidly to the viral infection and keeps the
viral infection under control.
C. Passive immunity mediated by maternal antibodies limits the spread of infection.
D. B and T lymphocytes recognize the virus and stimulate the innate immune
response.
E. The virus causes malignant transformation of respiratory mucosal epithelial cells,
and the malignant cells are recognized by the adaptive immune system.
ANS: B
The innate immune response to microbes develops within hours of infection, well before
the adaptive immune response. B and T lymphocytes are components of the adaptive
immune response, and they would not be able to respond to a newly encountered virus
before the innate immune response. An 8-year-old boy would no longer have maternal
antibodies from transplacental passive transfer and is unlikely to be breast-feeding, which
is another potential source of maternal antibodies. Malignant transformation takes months
or years to develop.
ANS: A
Highly diverse repertoires of specificities for antigens are found only in T and B
lymphocytes, which are the central cellular components of the adaptive immune system.
Both the innate and the adaptive immune systems use cell-associated and soluble
receptors to recognize microbes, display some degree of self-nonself discrimination, and
protect against viruses. On repeated exposure to the same microbe, the adaptive immune
response becomes more rapid and of greater magnitude; this is the manifestation of
memory.
5. Antibodies and T lymphocytes are the respective mediators of which two types of
immunity?
A. Innate and adaptive
B. Passive and active
C. Specific and nonspecific
D. Humoral and cell-mediated
E. Adult and neonatal
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-3
ANS: D
Both B and T lymphocytes are principal components of adaptive immunity. B
lymphocytes produce antibodies, which are the recognition and effector molecules of
humoral immune responses to extracellular pathogens. T cells recognize and promote
eradication of intracellular pathogens in cell-mediated immunity. Passive and active
immunity both can be mediated by either B or T lymphocytes. Specific immunity is
another term for adaptive immunity. Both B and T lymphocytes participate in adult
adaptive immunity but are still developing in the neonatal period.
6. A standard treatment of animal bite victims, when there is a possibility that the animal
was infected with the rabies virus, is administration of human immunoglobulin
preparations containing anti–rabies virus antibodies. Which type of immunity would be
established by this treatment?
A. Active humoral immunity
B. Passive humoral immunity
C. Active cell-mediated immunity
D. Passive cell-mediated immunity
E. Innate immunity
ANS: B
Humoral immunity is mediated by antibodies. The transfer of protective antibodies made
by one or more individuals into another individual is a form of passive humoral
immunity. Active immunity to an infection develops when an individual’s own immune
system responds to the microbe. Cell-mediated immunity is mediated by T lymphocytes,
not antibodies, and innate immunity is not mediated by either antibodies or T
lymphocytes.
ANS: D
Protection against infections after vaccination is due to immunologic memory of the
adaptive immune system. Memory is manifested as a more rapidly developing and
vigorous response on repeat exposure to an antigen compared with the first exposure.
Specificity and diversity are properties related to the range of antigenic structures
recognized by the immune system, and specialization is the ability of the adaptive
immune system to use distinct effector mechanisms for distinct infections.
8. A vaccine administered in the autumn of one year may protect against the prevalent
strain of influenza virus that originated in Hong Kong that same year, but it will not
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-4
protect against another strain of influenza virus that originated in Russia. This
phenomenon illustrates which property of the adaptive immune system?
A. Specificity
B. Amnesia
C. Specialization
D. Cultural diversity
E. Self-tolerance
ANS: A
Adaptive immune responses are highly specific for distinct molecular structures, which
may be present in a vaccine and be produced by one strain of virus but not by a closely
related strain. Amnesia, although generally not used in immunology, implies lack of
memory, but the efficacy of the vaccine against the Hong Kong strain implies it has
induced memory. The same effector mechanisms would be required to combat different
strains of influenza, and therefore failure of a vaccine to protect against two different
strains of virus is not related to specialization of effector functions.
ANS: A
T cells can be classified into effector subsets that perform different effector functions.
Most effector T cells are either helper T lymphocytes, which promote macrophage and B
cell responses to infections, or cytotoxic T lymphocytes, which directly kill infected cells.
Natural killer cells are not T lymphocytes. Antigen-presenting cells usually are not T
cells. Memory T cells are not effector T cells.
10. Which of the following cell types is required for all humoral immune responses?
A. Natural killer cells
B. Dendritic cells
C. Cytolytic T lymphocytes
D. B lymphocytes
E. Helper T lymphocytes
ANS: D
Humoral immune responses are antibody-mediated immune responses, and all antibodies
are made by B lymphocytes and by no other cell type.
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-5
A. Recognition phase
B. Activation phase
C. Effector phase
D. Homeostatic phase
E. Memory phase
ANS: C
The effector phase of an immune response occurs when cells or molecules eliminate the
microbe or microbial toxin. In a humoral immune response, the effector phase includes
secretion of antibody, binding of the antibody to the microbe or toxin, and subsequent
antibody-dependent elimination of the microbe or toxin. The recognition phase is the
initial binding of the antigen by the naive lymphocyte. The activation phase includes
proliferation and differentiation of lymphocytes in response to antigen recognition. The
homeostatic phase follows the effector phase, during which the response wanes. In the
memory phase, memory B cells and antibodies secreted by long-lived antibody-secreting
cells are “waiting” for a repeat exposure to the microbe.
12. Which of the following statements is consistent with the process of clonal selection?
A. The specificity of a lymphocyte antigen receptor changes to accommodate the
structure of an antigen that binds to it.
B. Many different antigen receptors with different specificities are expressed on each
lymphocyte.
C. Lymphocytes do not express antigen receptors on their cell surfaces until after
exposure to antigen.
D. The diversity of the lymphocyte repertoire for antigens is very small before
exposure to antigen but increases significantly after antigen exposure.
E. The diversity of the lymphocyte repertoire for antigens is very large before
exposure to antigen, with millions of different clones of lymphocytes, each having a
different specificity.
ANS: E
The clonal selection hypothesis accurately predicted that individuals possess large
numbers of different clones of lymphocytes before antigen exposure, with cells in each
clone expressing antigen receptors with a single identical specificity, but with different
specificities from other clones. Thus, the diversity of the lymphocyte repertoire is very
large even before antigen exposure. These receptors are expressed before antigen
exposure, and their specificities generally do not change in response to antigen.
13. Which of the following best describes clonal expansion in adaptive immune
responses?
A. Increased number of different lymphocyte clones, each clone specific for a
different antigen during the course of an infection
B. Increased number of different lymphocyte clones, each clone specific for a
different antigen during development of the immune system, before exposure to
antigen
C. Increased number of lymphocytes with identical specificities, all derived from a
single lymphocyte due to nonspecific stimuli from the innate immune system
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-6
ANS: D
Clonal expansion occurs during the activation phase of an adaptive immune response. A
single lymphocyte is stimulated to divide by antigen, and the progeny go through several
rounds of division until there are many lymphocytes, all with identical specificities, all
derived from one cell. The number of different clones is not influenced by antigen
exposure. Expansion does not refer to the size of the cells, although activated
lymphocytes are larger than their naive precursors.
14. The estimated number of distinct structures that can be recognized by the mammalian
adaptive immune system is
A. 1-10
B. 102-103
C. 103-105
D. 107-109
E. ∞
ANS: D
Although the theoretical number of antigen specificities of the adaptive immune system is
higher, estimates of the actual number of different antibody and T cell antigen receptor
specificities are in the range of 107-109. This number is large enough to accommodate
most of the diversity in molecular structures that the microbial world is capable of
producing.
15. Which of the following statements best describes the “two-signal requirement” for
naive lymphocyte activation?
A. Lymphocytes must recognize two different antigens to become activated.
B. Lymphocytes must recognize the same antigen at two sequential times to become
activated.
C. Lymphocytes must recognize antigen and respond to another signal generated by
microbial infection to become activated.
D. Both naive B and naive T lymphocytes must simultaneously recognize antigen for
either to be activated.
E. When lymphocytes recognize antigen, the antigen receptors must activate two-
signal transduction pathways to become activated.
ANS: C
Naive lymphocytes will not become activated by antigen alone (signal 1). In addition,
they require “costimulatory” signals (signal 2), which are either microbial products or
molecules on host cells induced by microbial infection. The molecules that provide signal
2 bind to receptors on the lymphocytes that are distinct from the clonally distributed
antigen receptors. Each lymphocyte cannot generally recognize more than one antigen.
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
Test Bank 1-7
16. In addition to T cells, which cell type is required for initiation of all T cell–mediated
immune responses?
A. Effector cells
B. Memory cells
C. Natural killer cells
D. Antigen-presenting cells
E. B lymphocytes
ANS: D
T cell–mediated immune responses are initiated when naive T cells are activated.
Antigen-presenting cells, such as dendritic cells, are required to display antigens (peptide-
MHC molecule complexes) for naive T cell recognition and to express costimulatory
molecules also needed for T cell activation. Memory cells, cytotoxic T cells, and B
lymphocytes are not involved in the initial activation of naive T lymphocytes.
Copyright © 2014, 2011, 2009, 2006, 2004, 2001 by Saunders, an imprint of Elsevier Inc.
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morrow, and will make it my charge to see that she is educated by
the Sisters as I have promised.’
“Excellency, it was a wise answer, putting off at once the burden of
his reproaches. He replied to me with your English word.
“‘Verdammt!’ said he, bringing his fist heavily upon the table, ‘she
shall go to no convent! You hear that, old man? Then speak no more
of it.’
“‘Herr Count,’ said I, ‘your wish is a command to me. Yet there is one
by whom it might not be so regarded. I speak of Christine’s husband,
Ugo Klun.’
“‘Her husband, Signor Andrea!’ he cried with a start of surprise. ‘But
he was shot in the mountains five months ago!’
“‘So the word goes,’ I answered; ‘but there is another story. Few
know the hills like Ugo, Herr Count.’
“It was plain that this suggestion came very ill to him. He got up from
his chair and paced the room twice before he spoke again.
“‘Pshaw!’ he exclaimed at last; ‘this is all nonsense. I have read the
corporal’s report with my own eyes. He killed the fellow himself, and
helped to bury him. Your tongue wags too fast, my friend; see that
you keep it still when the girl comes back.’
“I bowed my head, excellency, being careful to lose nothing of my
dignity before him. But when Christine came running back again, and
I observed the restlessness of his hands and the flush upon his face,
the whole of his secret was mine, and no longer was anything hid
from me.
“And in my heart I said: ‘God help them both if Ugo Klun is living still
in the cave above the Verbas.’”
CHAPTER XII
ANDREA PUTS THE QUESTION
“Signor, I did not take Christine back to Zlarin, as you may well
imagine. Rather, I laughed away her scruples, telling her that she
was worthy of any man’s love, and that it was her plain duty to
remain at the château. For the matter of that, though it was not
hidden from me that the Count loved her, none the less did I deem
any change in her condition impossible for months—nay, for years to
come. Paul Zaloski was not one to marry the first that he picked off
the roadside, without mature deliberation and a long-confirmed
resolve. It was even possible that no thought of marriage would enter
his head. The honour of a woman is a cheap commodity in Bosnia.
Things which would shame Western eyes are there without
significance. If the Count chose to offer love to the child, and to seek
no sanction of the Church, the world, I said, would applaud him. Nor
was it to be expected that the last of the Zaloskis should link his
name and his fortune with one whose story was like a fable from a
book and whose birthright was poverty. The very suggestion would
have been scouted in the market-place—the idea scoffed at as the
idea of a fool.
“As this was my thought, so was it the thought of others. Scarce had
I comforted the child, making merry over her suggestion that I should
take her back to Zlarin, when the priest met me in the garden of the
house, and asked me to his room, there to drink a glass of prune
brandy with him. I went the readier because he had shewn me some
friendship from the first, and I had found him to be a large-minded
man, very able to read the future; and when we had settled
ourselves near to his big fire of logs, and he had placed a bottle of
the liqueur, with cigars, at my elbow, we began to talk of many
things, but chiefly of Christine and of her prospects.
“‘We owe you hearty thanks, Signor Andrea,’ said he, while he filled
my glass and lighted a cheroot; ‘this is no weather to be out on the
hills, though your desire to see little Christine must have helped you
on the journey.’
“‘Diamine,’ replied I, ‘that is so; yet what says the proverb, “la
povertà è la madre di tutte le arti”—the poor must dance when the
rich pipe. Father, I could not refuse the Count’s invitation, and I doubt
not that he will hold the fact in remembrance. Three days of labour
have I lost in the coming, to say nothing of peril by the way. But this
would I do again to-morrow, and more, if little Christine could be
helped thereby.’
“He looked at me curiously, knocking the ashes off his cigar with
much deliberation.
“‘Undoubtedly,’ said he, ‘the child owes much to you. It is your
intention now, I understand, to carry her to Sebenico, and there to
place her with the Sisters of the Perpetual Adoration. That would be
a work of much merit.’
“‘Per nulla,’ said I, ‘all that is old talk. It is true that I mentioned the
matter to the Count when he saw fit to make a charge of neglect
against me; but he would not hear of it, and I confess that the burden
would be heavier than my shoulders could bear. She has a good
home here; why should I seek to check the providence of God and to
take her from it?’
“He heard me out, and then, going first to see that the door of the
room was shut, he drew his chair closer to mine, and unfolded his
scheme.
“‘Signor Andrea,’ he said, ‘we are both men of the world. If others
blind their eyes, that is no reason why we should walk in the
darkness with them. You especially should be very ready to hear of
any plan by which one you love may be snatched from the danger
which is threatening her soul and the soul of a man whose every
action I may not approve, but who is bound to me, nevertheless, by
many ties of affection. You follow me?’
“‘Perfectly,’ I replied, ‘remembering always my own exceeding
poverty.’
“‘As I remember it, and think of it in all I would do. It must be plain to
you that the Count, my master, is not the one to entertain, even for a
moment, the thought of marrying a little peasant girl out of Dalmatia
——’
“‘And why not?’ cried I.
“At this, excellency, he fidgeted upon his chair, and made a little
gesture of impatience.
“‘There are a hundred reasons,’ said he.
“‘Body of my soul,’ said I, ‘but I would like to hear them! And if it
comes to that, Father, let me tell you that I can conceive no greater
happiness for my child than a union so exalted, so noble, so worthy
of her beauty, as this would be. A hundred reasons! Santa Maria,
what talk!’
“I made my answer so, not believing a word I said, but intending to
hide from him any appearance of falling in too readily with his
suggestions. And in this I succeeded beyond my expectations. His
tone became less confident; he filled my glass again and drew his
chair yet nearer.
“‘You misunderstand me, my friend,’ said he. ‘It may be as you say;
he may even contemplate a step so disastrous to his ambitions and
his house. It lies upon us who have his interests at heart—and with
his interests the interests of the child also—to save him from himself
and his reckless will. We can do that in one way only—by sending
her to Sebenico.’
“I nodded my head gravely, and he proceeded:
“‘You, I am well aware, are in no way able to bear so heavy a
burden. That knowledge makes me the more willing to contemplate
some personal sacrifice in any proposal I have to make. I am not a
rich man, but if you, demanding the charge of Christine as a right,—
and I believe such guardianship was conferred upon you by her
brother’s will,—should carry her to the convent of the Perpetual
Adoration, I on my part will pay all the charges incurred by her
education there, and, moreover, will ask you to accept a thousand
francs a year for any expense you may be put to in the matter. Thus
alone can we save the Count from himself and the child from the
peril. You follow me, signor?’
“I followed him well enough, excellency, for my brain was very busy
as he spoke. And one thing was plain to me from the first. If Count
Paul meant to marry Christine, then could I look for something more
than a thousand francs a year from her. ‘She will never forget the
hand which gave her bread,’ I thought; ‘she may even appoint me to
some place about the house wherein the weight of my years may be
made light.’ On the other hand, if there was danger to be faced, then
was it my duty to accept the priest’s offer; ‘for,’ said I, ‘in that case
my presence will be a reproach to them, and they will turn me away
from their gates.’ But my difficulty was to read the Count’s intention
aright; and until I had so done it was not prudent that I should either
reject or accept the offer of the priest.
“‘Father,’ said I, ‘your words are the words of a righteous man. Let
me think upon them until to-morrow, and then you shall have my
answer. Meanwhile there is one possibility we have both forgotten in
weighing up these chances. I refer to the man Ugo Klun, who before
the law, if not before God, is Christine’s husband. How do we know
that he is dead?’
“This was my saying to him; yet, God knows, I had done better to
have cut off my right hand than to have spoken so foolishly. No
sooner had he heard the words than his face flushed with the blood
which ran up to it, and clutching me by the arm so that his fingers
seemed to touch my bone, he asked:
“‘My friend, do you think that Ugo Klun still lives, then?’
“‘How should I think it?’ replied I, for now I saw my folly; ‘it is at the
most an old woman’s tale. Was he not shot in the woods above the
Verbas? You have read the corporal’s report with your own eyes.
Accidente, Father, is not that enough?’
“He was walking about the room now, muttering to himself and
snapping his fingers. I do not think he heard my answer, for presently
he came and stood opposite to me, and with a great beat of his fist
on the table he cried:
“‘If the man lives, God helping me, I will find him.’
“He would have said more, but even as he was repeating his words
there was a loud knocking on the door of the room, and when we
opened quickly we found Hans, the steward, breathless with news
which sent us running to the park and crying for help as we ran.”
CHAPTER XIV
THE WHIRLING FIRE
“A word from Hans had carried us from the house, but the great
measure of his news we had while we drew our cloaks about us, and
armed ourselves with the guns which stood always in the hall of the
château.
“‘God of Heaven! that I did not tell her!’ gasped the trembling
steward. ‘She set off an hour ago to wait for my master in the park. I
never thought that she would pass the gates—how should I?—but
now comes the news that she is on the Jajce road! May the day be
black that sends me with such tidings to my master!’
“You, excellency, who are a stranger to the mountain land about
Jajce, may well know nothing of the meaning of such words as
these; yet to us, fed from our childhood on knowledge of the woods,
the message of Hans was like tidings of death itself. Even the
peasants in their numbers scarce dare venture out upon the hills
when the sun has set and the howling of the wolves makes dismal
music of the night. I, who know the passes as I know these waters,
would as soon cast myself down from yonder campanile as put
horses to my sleigh when the light of the sunshine is no longer upon
the snow. For if I did so, then might I look to leave my bones upon
the road—to be torn limb from limb by hungry beasts before the
lamps of the village were lost to my view. Christine was aware of no
such dangers. She had heard tales in the summer time of travellers
who had been devoured in the desolate places of the mountains by
ravenous packs; of bridal parties whose wedding journey had been a
journey to the terrible death which the hills hold in store for the
reckless. But that peril should await her within a stone’s throw of the
Count’s park was a thing she had not dreamt of. Eager to greet
again the man who was more dear to her than anything in the world,
thinking to please him by meeting his sleigh when it was yet some
distance from the house, she had ventured beyond the gates, and
had disappeared at last down the road to Jajce. A peasant had
remonstrated with her almost at the lodge of the park; but, his tongue
being unknown to her, she had laughed at his gesticulations, and
had gone on—God knew to what peril or to what fate.
“You may be sure that tidings of all this were spread abroad very
quickly by the men of the Count’s household. So fast did the news
run that we found quite a little company at the gates of the park, the
grooms being come from their stables, the woodlanders from their
huts. Of these some had torches in their hands, for it was now full
dark; some carried sticks, some lanterns. It was agreed quickly, even
above the babble of the talk, that we should strike all together down
the road to Jajce; and we trusted that the flare of our torches and the
sound of our voices would help to keep danger from the path. In this
we were not disappointed, though we had not gone more than half a
mile from the house when the need for our journey was made
manifest to us. We could see by the moon’s light, which shone
gloriously upon the whitened hills, the creeping forms of packs upon
the heights. From wood to wood they skulked—scores, nay
hundreds, of the famished beasts; and their howling was like a very
dirge of the dead. Mournfully, weirdly, now with a ferocity which
chilled the heart, now long-drawn as the sighs of damned spirits, the
haunting wail went up. That was a heavy winter—a winter when the
frost made the hills like domes of iron; when the snow lay heavy and
deep upon the grass; when the cattle died in the fields and the bears
came down even to the gardens of the houses. It was a season
when the wolf was to be found at the very gates of the city: when the
flesh was torn from the woodlanders’ bones as they sat in their huts;
a season spoken of now in hushed whispers, remembered by a
people born and bred to such perils.
“We could see the wolves skulking in the thickets, excellency, and
we drew the closer together at the sight, raising our voices and
kindling new torches. Yet so great was the hunger which the beasts
suffered that presently they became bolder, and began to collect in
little groups at the side of the path; while here and there one would
leap out, snapping his teeth and shewing us eyes which flashed red
in the dim light. And at this some of the grooms began to lose heart
and to cry out that our errand could end only in disaster to ourselves.
Even the steward was shaking with terror, and alternately
reproaching himself and assuring us that we were out on a fool’s
business.
“‘Holy Saints,’ he would cry, ‘how they bark; it is like the howling of
souls in hell! Did you hear that, Father? The Virgin pray for us. Yet
what can we do? That I should go to the Count with such a tale!
Think you that she is on the Jajce road? God help her, then. Yet she
might as well have looked towards Jézero. Fool that I was to think of
coming abroad!’
“‘You speak well, Master Hans,’ cried one of the grooms; ‘this is no
errand for men with wives and children to look to them. Not that I am
afraid. Who says that lies. I never yet feared man or beast—the Lord
have mercy on my soul.’
“A loud amen followed the rogue’s words, and we went on a little
further, descending deeper into the gorge and the darkness of the
woods. Here the road was very lonely, the trees bridging it over with
their branches, and the mountains above seeming to be fleecy
vapours hanging in the dome of the heavens. We could hear the
pursuing beasts pattering in the thickets at our side, and they howled
no longer—a sure sign that they were making ready to spring out
upon us. Presently Hans, who was in the van of the company,
stopped running altogether, and stood crying to us to listen to him.
“‘One word,’ said he; ‘we are going too fast for Father Mark—I can
see it by his step—and this is no place to rest in. It is my advice that
we return to the park and then venture a little way down the road to
Jézero. Had she passed by here, surely we had overtaken her
before this.’
“‘Aye, truly,’ cried another; ‘I am with Master Hans. Go back, say I,
and try towards Jézero. It’s here that Gozzo, the shepherd, was torn
last year, with his horse. You don’t forget that, Father? Not that I am
afraid—who says that lies.’
“They stood now clamouring round the priest, who, be it said to his
credit, was the best man among them. I can see him in my mind
now, excellency, panting heavily for want of his breath, and raising
his stick to bring them to silence.
“‘Who goes back,’ he said presently, ‘him will I bring to account here
upon the spot. Louts! do you leave a woman in her peril? What tale
will you carry to your master? That I should call such carrion my
children! Go on, I say, or you shall feel my cudgel on your shoulders!’
“They were a little shamefaced at this, all hanging very closely
together, and cocking their guns in readiness to fire. Even I, to whom
the bark of a wolf is no more than the clatter of a pebble in a brook,
found some comfort in the fact that I stood at the priest’s side, and
was thus in the centre of the group. As for the pack in the thicket, it
had become bolder at our halt, and we could now see the brutes,
some snarling in the bushes at our side, some jumping before us
from the wood to the road, and again from the road to the wood,
others dogging our steps and waiting for that moment when one
beast more bold than the rest should spring to the attack and a
hundred should follow him. So closely did they press upon us at last
that we formed a ring in the centre of the path, and fired a rattling
volley into them, a great flame of fire lighting the black place of the
thicket, and sending them howling and rolling in the depths of the
snow. Then, with another loud shout, we ran on through the wood,
and found ourselves, to our infinite satisfaction, again upon the open
road.
“You may imagine how, in all these trying moments, my thoughts had
turned upon Christine. If we, fifteen good men, with torches to light
us and guns in our hands, must press together to turn the peril from
our path, how, I asked, had it fared with an unarmed girl knowing
nothing of the peril or the road. One hope only I had, and it was this
—that Christine had passed through the wood while it was yet
daylight, and had taken shelter ultimately in the village lying between
the great house and Jajce. Yet I knew that this was unlikely; and it
was ever in my head that the child had perished already, and that we
must go to the Count with the story of her death in our mouths. Nor
could I imagine any man so bold that he should bear such news,
though it was my consolation that some other than myself must be
the messenger.
“I was pluming myself upon this, and telling myself that I, at any rate,
should be excused, even if I lost hope of recompense for my care of
the child, when Father Mark of a sudden stopped us in our walk and
raised his hands warningly.
“‘Hush!’ said he; ‘I thought that I heard a woman’s cry!’
“We all listened with bent ears, but so loud was the howling of the
brutes about us that we caught no sound, and the priest spoke
again.
“‘I am sure that I was not deceived,’ said he; ‘it was a cry that I
heard, and it came from the hamlet yonder.’”
CHAPTER XV
THE APPARITION IN THE CLOISTERS