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 Overview: "Pharmacology: A Patient-Centered
Nursing Process Approach, 10th Edition" by Linda E.
McCuistion is a comprehensive textbook designed to
provide nursing students and professionals with a
thorough understanding of pharmacology within a
patient-centered framework. This edition
emphasizes the nursing process and patient-
centered care, focusing on the safe and effective
use of medications. The textbook covers drug
classifications, mechanisms of action, therapeutic
effects, side effects, and nursing considerations,
preparing nurses to deliver high-quality, evidence-
based care.
Structure and Organization: The textbook is
organized into twelve units, each focusing on
different aspects of pharmacology. Each chapter
includes learning objectives, key terms, drug tables,
nursing process summaries, critical thinking
exercises, and review questions to facilitate
understanding and application of the material.
Unit I: Introduction to Pharmacology
1. Pharmacology and the Nursing Process:
 • Overview of pharmacology and its
importance in nursing practice.
• The nursing process (assessment,
diagnosis, planning, implementation,
evaluation) as a framework for medication
administration.
• Principles of patient-centered care in
pharmacology.
2. Pharmacologic Principles:
• Basic concepts of pharmacokinetics
(absorption, distribution, metabolism,
excretion) and pharmacodynamics
(mechanisms of action, therapeutic effects).
• Factors affecting drug action, including age,
weight, genetics, and health status.
• The importance of understanding drug
interactions and adverse effects.
Unit II: Drugs Affecting the Autonomic Nervous
System
3. Adrenergic Drugs:
• Overview of adrenergic agonists and
antagonists.
 • Mechanisms of action and therapeutic uses
of adrenergic drugs.
• Nursing considerations for patients receiving
adrenergic drugs.
4. Cholinergic Drugs:
• Overview of cholinergic agonists and
antagonists.
• Mechanisms of action and therapeutic uses
of cholinergic drugs.
• Nursing considerations for patients receiving
cholinergic drugs.
Unit III: Drugs Affecting the Central Nervous
System
5. Central Nervous System Stimulants:
• Overview of CNS stimulants, including
amphetamines, anorexiants, and analeptics.
• Mechanisms of action and therapeutic uses
of CNS stimulants.
• Nursing considerations for patients receiving
CNS stimulants.
6. Central Nervous System Depressants:
• Overview of CNS depressants, including
sedatives, hypnotics, and anxiolytics.
 • Mechanisms of action and therapeutic uses
of CNS depressants.
• Nursing considerations for patients receiving
CNS depressants.
7. Antidepressants and Mood Stabilizers:
• Overview of antidepressants (SSRIs, SNRIs,
TCAs, MAOIs) and mood stabilizers.
• Mechanisms of action and therapeutic uses
of these medications.
• Nursing considerations for patients receiving
antidepressants and mood stabilizers.
Unit IV: Drugs Affecting the Cardiovascular
System
8. Antihypertensive Drugs:
• Overview of antihypertensive drug classes,
including ACE inhibitors, ARBs, beta-
blockers, and diuretics.
• Mechanisms of action and therapeutic uses
of antihypertensive drugs.
• Nursing considerations for patients receiving
antihypertensive drugs.
9. Antianginal Drugs:
 • Overview of antianginal drugs, including
nitrates, beta-blockers, and calcium channel
blockers.
• Mechanisms of action and therapeutic uses
of antianginal drugs.
• Nursing considerations for patients receiving
antianginal drugs.
10. Anticoagulants, Antiplatelets, and
Thrombolytics:
• Overview of anticoagulants, antiplatelets,
and thrombolytics.
• Mechanisms of action and therapeutic uses
of these medications.
• Nursing considerations for patients receiving
anticoagulants, antiplatelets, and
thrombolytics.
Unit V: Drugs Affecting the Respiratory System
11. Drugs for Respiratory Disorders:
• Overview of medications used to treat
respiratory disorders, including
bronchodilators, corticosteroids, and
mucolytics.
 • Mechanisms of action and therapeutic uses
of respiratory drugs.
• Nursing considerations for patients receiving
respiratory drugs.
Unit VI: Drugs Affecting the Gastrointestinal
System
12. Drugs for Gastrointestinal Disorders:
• Overview of medications used to treat
gastrointestinal disorders, including
antacids, laxatives, and antiemetics.
• Mechanisms of action and therapeutic uses
of gastrointestinal drugs.
• Nursing considerations for patients receiving
gastrointestinal drugs.
Unit VII: Drugs Affecting the Endocrine System
13. Drugs for Diabetes Mellitus:
• Overview of medications used to treat
diabetes mellitus, including insulin and oral
hypoglycemics.
• Mechanisms of action and therapeutic uses
of diabetes medications.
 • Nursing considerations for patients receiving
diabetes medications.
14. Drugs for Thyroid Disorders:
• Overview of medications used to treat
thyroid disorders, including thyroid
hormones and antithyroid drugs.
• Mechanisms of action and therapeutic uses
of thyroid medications.
• Nursing considerations for patients receiving
thyroid medications.
Unit VIII: Drugs Affecting the Reproductive
System
15. Drugs for Reproductive Health:
• Overview of medications used for
reproductive health, including
contraceptives, hormone replacement
therapy, and drugs for erectile dysfunction.
• Mechanisms of action and therapeutic uses
of reproductive health medications.
• Nursing considerations for patients receiving
reproductive health medications.
Unit IX: Anti-Infective Drugs
 16. Antibiotics:
• Overview of antibiotic classes, including
penicillins, cephalosporins, and macrolides.
• Mechanisms of action and therapeutic uses
of antibiotics.
• Nursing considerations for patients receiving
antibiotics.
17. Antivirals and Antifungals:
• Overview of antiviral and antifungal
medications.
• Mechanisms of action and therapeutic uses
of these medications.
• Nursing considerations for patients receiving
antivirals and antifungals.
Unit X: Drugs for Pain and Inflammation
18. Analgesics:
• Overview of analgesics, including opioids,
non-opioids, and adjuvant analgesics.
• Mechanisms of action and therapeutic uses
of analgesics.
• Nursing considerations for patients receiving
analgesics.
19. Anti-Inflammatory Drugs:
 • Overview of anti-inflammatory drugs,
including NSAIDs and corticosteroids.
• Mechanisms of action and therapeutic uses
of anti-inflammatory drugs.
• Nursing considerations for patients receiving
anti-inflammatory drugs.
Unit XI: Drugs for Immune System Modulation
20. Immunosuppressants and
Immunostimulants:
• Overview of immunosuppressants and
immunostimulants.
• Mechanisms of action and therapeutic uses
of these medications.
• Nursing considerations for patients receiving
immunosuppressants and
immunostimulants.
Unit XII: Special Topics in Pharmacology
21. Pediatric Pharmacology:
• Overview of pharmacological principles in
pediatric patients.
• Differences in drug absorption, distribution,
metabolism, and excretion in children.
 • Nursing considerations for pediatric
medication administration.
22. Geriatric Pharmacology:
• Overview of pharmacological principles in
geriatric patients.
• Differences in drug absorption, distribution,
metabolism, and excretion in older adults.
• Nursing considerations for geriatric
medication administration.
23. Pregnancy and Lactation:
• Overview of pharmacological principles
during pregnancy and lactation.
• Drug safety and teratogenicity.
• Nursing considerations for medication
administration in pregnant and lactating
patients.
Pedagogical Features:
• Case Studies: Real-world scenarios illustrating
key concepts and applications in pharmacology.
• Critical Thinking Exercises: Activities
designed to enhance analytical and problem-
solving skills.
 • Drug Tables: Detailed tables summarizing drug
classifications, mechanisms of action,
therapeutic uses, and side effects.
• Nursing Process Summaries: Summaries of
the nursing process for specific drug classes,
including assessment, diagnosis, planning,
implementation, and evaluation.
• Reflective Questions: Questions at the end of
each chapter to encourage reflection and
application of concepts.
• Glossary: Definitions of key terms and concepts
in pharmacology.
Conclusion: "Pharmacology: A Patient-Centered
Nursing Process Approach, 10th Edition" is an
essential resource for nursing students and
professionals. Its comprehensive coverage of
pharmacological principles, integration of the nursing
process, and emphasis on patient-centered care
prepare readers to navigate the complexities of
medication administration in diverse patient
populations. The textbook's focus on critical thinking,
evidence-based practice, and effective
communication ensures that nurses are equipped
with the knowledge and skills necessary to provide
 safe and effective pharmacological care and
improve patient outcomes.

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