DRUG ORDER (Generic name, brand name, classification, dosage, route, frequency) Generic name: omeprazole Brand name:

Omeprazole Classification: Therapeutic: Antiulcer drug Pharmacologic: Proton pump inhibitor Route: IVTT Dosage: 1 gm Frequency: q 24h

CONTRAINDICATIONS MECHANISM OF ACTION INDICATIONS ADVERSE EFFECTS OF THE DRUGS

NURSING RESPONSIBILITIES/ PRECAUTIONS

Reduces gastric acid secretion and increases gastric mucus and bicarbonate production, creating protective coating on gastric mucosa and easing discomfort from excess gastric acid

-To reduce risk of duodenal ulcers caused by Helicobaster pylori -Short term treatment of active duodenal ulcer

Contraindicated in: -Hypersensitivity to drug or its components -Hepatic disease

CNS: dizziness, headache, asthenia GI: nausea, vomiting, diarrhea, constipation, abdominal pain Derm: rash Musculoskeletal: back pain Respiratory: cough, upper respiratory tract infection

 Tell patient to take 30 to 60 minutes before a meal, preferably in morning.  Instruct patient to swallow capsules or tablets whole and not to chew or crush them. If he can t swallow capsule, tell him he may open it, carefully sprinkle and mix entire contents into 1 tbsp of cool applesauce, and swallow immediately with glass of water.  Inform patient taking OTC delayed release tablets for heartburn that full effect may take 1 to 4 days. Advise him not to take tablets for more than 14 days without consulting healthcare professional.

DRUG ORDER (Generic name, brand name, classification, dosage, route, frequency) Generic name: cefuroxime Brand name: Ceftin Classification: Therapeutic: Antiinfective Pharmacologic: Secondgeneration cephalosporin Route: IVTT Dosage: 2gram Frequency: q OD

CONTRAINDICATIONS MECHANISM OF ACTION INDICATIONS ADVERSE EFFECTS OF THE DRUGS

NURSING RESPONSIBILITIES/ PRECAUTIONS

Interferes with bacterial cell-wall synthesis and division by binding to cell wall, causing cell to die. Active against gram negative and gram positive bacteria, with expanded activity against gramnegative bacteria.

Moderate to severe infections, including those of skin, bone, joints, urinary or respiratory tract, gynecologic infections

-Hypersensitivity to cephalosporins or penicillins -Carnitine deficiency - renal or hepatic impairment

CNS: headache, hyperactivity, hypertonia, seizures GI: nausea, vomiting, diarrhea, abdominal pain, dyspepsia, pseudomembranous colitis GU: hematuria, vaginal candidiasis, renal dysfunction, acute renal failure Hematologic: hemolytic anemia, aplastic anemia, hemorrhage Hepatic: hepatic dysfunction Metabolic: hyperglycemia Skin: toxic epidermal necrolysis, erythema multiforme, Stevens-Johnson syndrome Other: allergic reaction, drug fever, superinfection, anaphylaxis

 Advise patient to immediately report rash or bleeding tendency. Instruct patient to take drug with food every 12 hours as prescribed.  Teach patient how to recognize signs and symptoms of superinfection. Instruct him to report these right away.  Advise patient to report CNS changes.  As appropriate, review all other significant and lifethreatening adverse reactions and interactions, especially those related to the drugs, tests, and foods mentioned above.

DRUG ORDER (Generic name, brand name, classification, dosage, route, frequency)

CONTRAINDICATIONS MECHANISM OF ACTION INDICATIONS ADVERSE EFFECTS OF THE DRUGS

NURSING RESPONSIBILITIES/ PRECAUTIONS

Stimulate smooth Generic name: castor muscle of bowel, oil increasing Brand name: laxatives intestinal contractions; increase Classification: stool bulk by causing Therapeutic: water retention Pharmacologic: and inhibiting digestion in Route: stomach. Also soften Dosage: 60ml hard feces, promoting their passage through Frequency: q 60ml lower intestine.

Treatment of constipation, prevention of constipation in patients who should not strain during defecation (for example, after anorectal surgery or myocardial infarction), colonic evacuation for rectal and bowel examination

Contraindicated in hypersensitivity to drug or its components, intestinal obstruction, undiagnosed abdominal pain, suspected appendicitis, and fecal impaction Use cautiously in severe cardiovascular disease, anal or rectal fissures, enteritis, ulcerative colitis, diverticulitis, pregnant or breastfeeding patients,

GI: nausea; vomiting; diarrhea; esophageal, gastric, small-intestine, or rectal obstruction (with dry form of drug); abdominal cramps in severe constipation; anorexia GU: reddish-pink discoloration of alkaline urine, yellow-brown discoloration of acidic urine Metabolic: alkalosis, fluid and electrolyte imbalances Musculoskeletal: tetany Other: laxative dependence (with excessive long-term use)

 Monitor fluid and electrolyte balance.